Prolapse and hernia of ovary and fallopian tube

N14_PROHERNOV

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N83.4
  • Hospital discharge: ICD-9 6204
  • Hospital discharge: ICD-8 623
  • Cause of death: ICD-10 N83.4
  • Cause of death: ICD-9 6204
  • Cause of death: ICD-8 623

2 out of 7 registries used, show all original rules.

1546

4. Check minimum number of events

None

1546

5. Include endpoints

None

1546

6. Filter based on genotype QC (FinnGen only)

1546

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N83
Name in latin
Prolapsus et hernia ovarii et tubae uterinae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 32212 32212 -
Only index persons 17393 17393 -
Unadjusted period prevalence (%)
Whole population 0.92 0.92 -
Only index persons 0.64 0.64 -
Median age at first event (years)
Whole population - 53.57 -
Only index persons - 47.91 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1546 1546 -
Unadjusted period prevalence (%) 0.53 0.53 -
Median age at first event (years) 42.20 42.20 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1413
Matched controls
13944
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
62301
ICD-8 Finland
Uterovaginal prolapse, Cystocele alia
+∞
323.0
634
*
62398
ICD-8 Finland
Uterovaginal prolapse, Alia
+∞
323.0
349
*
62310
ICD-8 Finland
Uterovaginal prolapse, Rectocele
+∞
323.0
378
*
78629
ICD-8 Finland
Symptoms referable to genito-urinary system, Incontinentia urinae
75.7
323.0
459
88
N81.6
ICD-10 Finland
Rectocele
74.9
207.1
235
37
62300
ICD-8 Finland
Uterovaginal prolapse, Prolapsus vesicae
+∞
175.9
166
*
62399
ICD-8 Finland
Uterovaginal prolapse, Other and unspecified
+∞
162.9
154
*
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
412.5
152.5
151
*
N81.1
ICD-10 Finland
Cystocele
61.4
149.3
175
32
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
+∞
136.0
129
*
62699
ICD-8 Finland
Disorders of menstruation, Other
+∞
124.2
118
*
N81.5
ICD-10 Finland
Vaginal enterocele
585.1
111.9
110
*
62330
ICD-8 Finland
Uterovaginal prolapse, Vaginal enterocele
+∞
106.1
101
*
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
285.6
105.8
107
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
71.0
76.8
88
13
N95.0
ICD-10 Finland
Postmenopausal bleeding
26.1
76.6
108
44
62620
ICD-8 Finland
Disorders of menstruation, Excessive
+∞
75.3
72
*
N99.3
ICD-10 Finland
Prolapse of vaginal vault after hysterectomy
65.2
75.0
87
14
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
8.4
69.8
162
212
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
55.6
67.3
80
15
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
+∞
66.9
64
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.0
65.5
302
892
62670
ICD-8 Finland
Disorders of menstruation, Postmenopausal bleeding
+∞
63.7
61
*
8113
FHL
Fractional scraping
9.5
63.4
136
155
62392
ICD-8 Finland
NA
+∞
61.6
59
*
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
+∞
60.5
58
*
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
59.5
57
*
8432
FHL
Anterior and / or posterior colaphia
205.7
58.2
60
*
62391
ICD-8 Finland
Uterovaginal prolapse, Elongatio cervicis
+∞
54.2
52
*
LEF40
NOMESCO Finland
Vaginal repair of enterocele
+∞
53.2
51
*
62400
ICD-8 Finland
Malposition of uterus, Retroversion and retroflexion
+∞
53.2
51
*
6180C
ICD-9 Finland
Genital prolapse, Prolapse of vaginal walls without mention of uterine prolapse[RECTOCELE]
+∞
50.0
48
*
N84.0
ICD-10 Finland
Polyp of corpus uteri
63.8
48.3
56
9
62650
ICD-8 Finland
Disorders of menstruation, Irregular
+∞
47.9
46
*
62533
ICD-8 Finland
Other diseases of uterus, Adenomyosis uteri
+∞
45.8
44
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.3
44.6
978
6926
6256A
ICD-9 Finland
Pain and other symptoms associated with female genital organs, Stress incontinence, female
10.0
42.9
88
92
8433
FHL
Anterior and / or posterior colporal and cervical amputation (eg Manchester)
208.0
39.8
41
*
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
10.4
38.4
77
77
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
382.1
38.0
38
*
6180A
ICD-9 Finland
Genital prolapse, Prolapse of vaginal walls without mention of uterine prolapse[CYSTOCELE]
+∞
35.4
34
*
7434
FHL
Abdominal urethrocystopexy
10.3
34.5
69
69
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.0
34.1
226
844
N39.3
ICD-10 Finland
Stress incontinence
3.5
32.8
165
506
J01EA01
ATC
trimethoprim; systemic
2.0
31.7
612
3866
N83.4
ICD-10 Finland
Prolapse and hernia of ovary and fallopian tube
+∞
31.2
30
*
6262A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Excessive or frequent menstruation[HYPERMENORRHOEA]
+∞
30.2
29
*
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
29.7
459
2635
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
80.7
28.7
32
*
R15
ICD-10 Finland
Faecal incontinence
5.3
28.3
90
178
62698
ICD-8 Finland
Disorders of menstruation, Alia definita
+∞
27.0
26
*
LEF53
NOMESCO Finland
Vaginal colpopexy after previous hysterectomy
97.3
26.6
29
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
26.1
347
1851
62521
ICD-8 Finland
Other diseases of uterus, Hyperplasia glandularis cystica endometrii
+∞
26.0
25
*
6271A
ICD-9 Finland
Menopausal and postmenopausal disorders, Postmenopausal bleeding
+∞
26.0
25
*
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
+∞
26.0
25
*
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
24.2
25.6
36
15
J01MA02
ATC
ciprofloxacin; systemic
1.9
25.4
579
3791
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
14.2
24.7
42
30
8436
FHL
Vaginal hysterectomy and anterior cataract
70.2
24.7
28
*
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
+∞
23.9
23
*
6181A
ICD-9 Finland
Genital prolapse, Uterine prolapse without mention of vaginal wall prolapse
+∞
22.9
22
*
J01CA08
ATC
pivmecillinam; oral
1.8
22.8
897
6909
62530
ICD-8 Finland
Other diseases of uterus, Endometriosis ovarii
+∞
21.8
21
*
62532
ICD-8 Finland
Other diseases of uterus, Endometriosis retro-cervicalis sive retrouterina
+∞
21.8
21
*
62630
ICD-8 Finland
Disorders of menstruation, Painful
+∞
21.8
21
*
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.1
21.6
290
1537
LEG10
NOMESCO Finland
Vaginal urethrocystopexy
5.0
21.5
70
143
21899
ICD-8 Finland
Uterine fibroma
2.5
21.3
185
800
62320
ICD-8 Finland
Uterovaginal prolapse, Urethrocele
+∞
20.8
20
*
G04BD07
ATC
tolterodine; oral
2.7
20.4
152
601
6186A
ICD-9 Finland
Genital prolapse, Vaginal enterocele, congenital or acquired
+∞
19.7
19
*
6270A
ICD-9 Finland
Menopausal and postmenopausal disorders, Premenopausal menorrhagia
+∞
19.7
19
*
LEF50
NOMESCO Finland
Colpopexy after previous hysterectomy
199.9
19.5
20
*
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
9.9
19.5
39
40
J01DA01
ATC
[U] cefalexin; systemic
1.7
18.9
832
6441
JGC01
NOMESCO Finland
Laparoscopic rectopexy
12.8
18.8
33
26
G04BD04
ATC
oxybutynin; oral, transdermal
2.4
18.7
164
712
8435
FHL
Enterose selection (includes lapchotomy Moschowitz operation with modifications)
189.7
18.5
19
*
M48.0
ICD-10 Finland
Spinal stenosis
2.1
18.4
233
1200
A02BC03
ATC
lansoprazole; oral
1.7
18.2
458
3009
XKC03
NOMESCO Finland
Water cystometry
4.5
18.0
65
149
UJF32
NOMESCO Finland
Coloscopy
1.8
17.9
375
2324
G03CA04
ATC
estriol; systemic, vaginal
1.9
17.9
308
1786
N02AX02
ATC
tramadol; systemic, rectal
1.7
17.8
565
3967
N30.0
ICD-10 Finland
Acute cystitis
1.9
17.7
319
1882
UKC02
NOMESCO Finland
Cystoscopy
2.3
17.6
171
781
G04BD12
ATC
mirabegron; oral
2.2
17.5
183
865
ULC02
NOMESCO Finland
Hysteroscopy
8.7
17.3
37
43
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.8
17.2
366
2275
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.9
17.1
273
1534
G04BD08
ATC
solifenacin; oral
2.5
16.8
134
552
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
3.1
16.6
94
312
LEF51
NOMESCO Finland
Laparoscopic colpopexy after previous hysterectomy
+∞
16.6
16
*
62191
ICD-8 Finland
Other diseases of cervix, Dysplasia portionis uteri
+∞
16.6
16
*
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
89.9
16.5
18
*
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.2
16.3
88
284
K62.3
ICD-10 Finland
Rectal prolapse
5.0
16.0
51
103
N85.1
ICD-10 Finland
Endometrial adenomatous hyperplasia
+∞
15.6
15
*
LCA10
NOMESCO Finland
Curettage of body of uterus
26.2
15.5
21
8
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
84.8
15.5
17
*
N81.4
ICD-10 Finland
Uterovaginal prolapse, unspecified
22.0
15.4
22
10
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
15.0
327
2038
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
14.8
400
2653
62000
ICD-8 Finland
Infective diseases of cervix uteri, Cervicitis chronica
+∞
14.5
14
*
61521
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) corporis lutei ovarii
+∞
14.5
14
*
21900
ICD-8 Finland
Other benign neoplasm of uterus, Papiloma, polyp
4.4
14.0
50
114
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
13.8
415
2824
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.2
13.7
150
719
G04BD09
ATC
trospium; oral
3.1
13.7
76
251
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.8
13.6
87
314
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.3
13.5
130
589
R03AC02
ATC
salbutamol; inhalant
1.5
13.5
613
4621
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
+∞
13.5
13
*
62522
ICD-8 Finland
Other diseases of uterus, Polyposis non neoplastica uteri
+∞
13.5
13
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.0
13.5
80
277
A03FA02
ATC
cisapride; oral, rectal
2.0
13.4
170
872
G04AC01
ATC
NA
2.5
13.3
104
424
J02AC01
ATC
fluconazole; systemic
1.6
13.3
466
3294
N03AX16
ATC
pregabalin; oral
1.7
13.2
327
2105
LCA06
NOMESCO Finland
Biopsy of endometrium
3.0
13.2
77
264
Y4300
ICD-8 Finland
Preventive sterilization, Legal sterilization, medical reasons (illness or physical injury)
3.3
13.1
66
204
R03BA05
ATC
fluticasone; inhalant
1.8
13.1
227
1306
M01AX05
ATC
glucosamine; oral
1.6
13.0
424
2937
A02BC05
ATC
esomeprazole; systemic
1.6
12.9
519
3788
A02BA02
ATC
ranitidine; systemic
1.7
12.9
327
2119
J01FA06
ATC
roxithromycin; oral
1.5
12.7
541
3995
XLA10
NOMESCO Finland
NA
3.9
12.6
51
132
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
12.5
534
3946
XKD03
NOMESCO Finland
Urethral pressure profilometry
3.9
12.4
51
134
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
129.3
12.4
13
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
12.4
252
1527
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.2
12.2
126
592
7436
FHL
Combined lower upper upper surgery
18.0
12.0
18
10
M54.5
ICD-10 Finland
Low back pain
1.6
11.9
379
2602
M20.1
ICD-10 Finland
Hallux valgus (acquired)
2.0
11.8
154
799
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
11.8
491
3594
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.4
11.7
102
439
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.7
11.6
262
1638
LEF96
NOMESCO Finland
Other operation for prolapse of uterus or vaginal vault
64.6
11.5
13
*
XJH00
NOMESCO Finland
Transanal ultrasonography
7.7
11.5
26
34
J01DB01
ATC
cefalexin; oral
1.5
11.5
980
8352
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
11.4
341
2299
6210A
ICD-9 Finland
Disorders of uterus, not elsewhere classified, Polyp of corpus uteri
+∞
11.4
11
*
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
1.6
11.4
413
2921
N84.1
ICD-10 Finland
Polyp of cervix uteri
34.8
11.2
14
*
R01AD08
ATC
fluticasone; nasal
1.7
11.1
282
1820
JG1JB
NOMESCO Finland
Defekography with X-ray
16.9
11.1
17
10
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
11.1
300
1972
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.1
11.0
127
624
J01MA06
ATC
norfloxacin; oral
1.7
11.0
275
1766
A02BC02
ATC
pantoprazole; systemic
1.5
11.0
857
7132
H02AB06
ATC
prednisolone; systemic
1.5
10.9
586
4513
N81.3
ICD-10 Finland
Complete uterovaginal prolapse
43.0
10.9
13
*
M70.6
ICD-10 Finland
Trochanteric bursitis
1.8
10.8
215
1292
U02
ICPC
Urinary frequency/urgency
1.7
10.6
227
1396
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.9
10.4
62
217
N80.0
ICD-10 Finland
Endometriosis of uterus
+∞
10.4
10
*
62341
ICD-8 Finland
NA
+∞
10.4
10
*
R32
ICD-10 Finland
Unspecified urinary incontinence
2.9
10.3
61
212
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.0
10.3
130
662
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
1.8
10.3
200
1191
J01AA02
ATC
doxycycline; systemic
1.5
10.3
984
8476
C05AA08
ATC
fluocortolone; rectal, topical
1.8
10.0
180
1045
R03DC03
ATC
montelukast; oral
1.8
10.0
178
1031
8204
FHL
Salpingo-oophorectomy
5.4
10.0
29
54
N02BE01
ATC
paracetamol; systemic, rectal
1.6
10.0
1179
10593
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.1
9.9
53
173
8431
FHL
Colpopexia
39.8
9.9
12
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
9.9
506
3835
M25.5
ICD-10 Finland
Pain in joint
1.6
9.9
296
1988
N06AA09
ATC
amitriptyline; systemic
1.8
9.8
161
907
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
9.8
180
1053
M02AA07
ATC
piroxicam; topical
1.4
9.8
601
4721
L03
ICPC
Low back symptom/complaint
1.6
9.8
301
2035
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
9.8
191
1139
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
9.8
169
970
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.6
9.7
67
257
A02BA04
ATC
nizatidine; systemic
1.9
9.6
148
818
M01AC06
ATC
meloxicam; systemic, rectal
1.5
9.5
500
3806
G04AB05
ATC
NA
2.3
9.5
85
373
R2110
NOMESCO Finland
Giving the first information
2.6
9.4
70
277
M01AB05
ATC
diclofenac; systemic, rectal
1.4
9.4
739
6070
62198
ICD-8 Finland
Other diseases of cervix, Alii definiti
+∞
9.3
9
*
6170A
ICD-9 Finland
Endometriosis of uterus
+∞
9.3
9
*
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
3.1
9.2
50
165
L08
ICPC
Shoulder symptom/complaint
1.6
9.2
229
1464
XKD00
NOMESCO Finland
Uroflowmetry
2.6
9.2
65
251
M01AE02
ATC
naproxen; oral, rectal
1.4
9.1
608
4834
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
1.7
9.0
223
1420
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
9.0
399
2923
J01XE01
ATC
nitrofurantoin; oral
2.6
9.0
62
239
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.3
8.9
84
377
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
3.5
8.9
40
115
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
8.9
272
1832
WX320
NOMESCO Finland
Spinalanesthesy
1.6
8.9
269
1809
JG1JG
NOMESCO Finland
MRI of rectal function (MR defecography)
23.8
8.8
12
5
M01AB55
ATC
diclofenac, combinations; oral
1.9
8.8
136
747
R96
ICPC
Asthma
2.0
8.8
119
625
U01
ICPC
Dysuria/painful urination
1.9
8.8
123
656
H02AB04
ATC
methylprednisolone; systemic
1.7
8.8
193
1192
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.4
8.8
70
292
M01AH05
ATC
etoricoxib; oral
1.4
8.7
578
4579
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
9.4
8.7
17
18
G03CC04
ATC
estrone; systemic
1.8
8.7
144
816
M01AX17
ATC
nimesulide; oral
1.5
8.6
372
2709
J01CA04
ATC
amoxicillin; systemic
1.4
8.6
922
7947
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.6
431
3234
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
3.3
8.5
41
125
H02.3
ICD-10 Finland
Blepharochalasis
2.0
8.5
104
525
U71
ICPC
Cystitis/urinary infection other
1.9
8.4
116
614
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
8.4
695
5713
78679
ICD-8 Finland
Symptoms referable to genito-urinary system, Algos genitalium aliud sive NUD
27.3
8.4
11
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
8.4
432
3257
59502
ICD-8 Finland
Cystitis, Chronica
19.9
8.4
12
6
8449
FHL
Other measure in this category
89.3
8.4
9
*
G03CB01
ATC
dienestrol; oral, vaginal
1.9
8.3
119
637
C01DA14
ATC
isosorbide mononitrate; oral
1.5
8.3
349
2521
LEF54
NOMESCO Finland
Repair of apical defect with mesh
+∞
8.3
8
*
62700
ICD-8 Finland
Menopausal symptoms
+∞
8.3
8
*
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
+∞
8.3
8
*
62531
ICD-8 Finland
Other diseases of uterus, Endometriosis serosae pelvis
+∞
8.3
8
*
62801
ICD-8 Finland
Sterility, female, Sterilitas secundaria
+∞
8.3
8
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
8.3
384
2834
LCD10
NOMESCO Finland
Vaginal hysterectomy
6.2
8.2
21
34
A02BC01
ATC
omeprazole; systemic
1.5
8.2
395
2940
6185A
ICD-9 Finland
Genital prolapse, Prolapse of vaginal vault after hysterectomy
33.1
8.0
10
*
R01AD09
ATC
mometasone; nasal
1.4
7.9
416
3140
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.9
275
1904
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
7.8
224
1480
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.8
363
2676
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
3.2
7.8
39
123
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
7.8
376
2793
SPAT1325
SPAT
Vaccination
1.4
7.7
498
3902
N83.0
ICD-10 Finland
Follicular cyst of ovary
44.6
7.7
9
*
R06AX22
ATC
ebastine; oral
1.7
7.6
170
1054
Y0609
ICD-8 Finland
Examination of the urinary and genital organs, Genital organs
3.3
7.6
36
109
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
7.6
166
1020
204
Kela drug reimbursment
Leukemia lymphatica
2.0
7.5
93
473
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
7.5
327
2376
61620
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic congestion, female
24.8
7.5
10
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
7.5
190
1220
M79.6
ICD-10 Finland
Pain in limb
1.4
7.5
428
3276
ULA02
NOMESCO Finland
Kolposcopy
2.4
7.4
59
248
LDW96
NOMESCO Finland
Other operation on cervix uteri
79.4
7.4
8
*
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.1
7.3
83
409
K62.2
ICD-10 Finland
Anal prolapse
5.2
7.3
21
40
M03BX02
ATC
tizanidine; oral
1.4
7.3
572
4625
62538
ICD-8 Finland
Other diseases of uterus, Endometriosis alia
+∞
7.3
7
*
62110
ICD-8 Finland
Other diseases of cervix, Erythroplasia of cervix
+∞
7.3
7
*
62610
ICD-8 Finland
Disorders of menstruation, Hypomenorrhoea
+∞
7.3
7
*
N80.1
ICD-10 Finland
Endometriosis of ovary
+∞
7.3
7
*
62640
ICD-8 Finland
Disorders of menstruation, Frequent
+∞
7.3
7
*
6182A
ICD-9 Finland
Genital prolapse, Uterovaginal prolapse, incomplete
+∞
7.3
7
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
+∞
7.3
7
*
N03AX12
ATC
gabapentin; oral
1.6
7.3
180
1149
M02AA10
ATC
ketoprofen; topical
1.5
7.2
244
1677
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.0
7.2
84
417
LEG12
NOMESCO Finland
Transobturatoric tape
4.4
7.2
24
54
J05AB11
ATC
valaciclovir; oral
1.7
7.1
160
991
R35
ICD-10 Finland
Polyuria
2.5
7.1
54
221
N06AX21
ATC
duloxetine; oral
1.8
7.1
115
648
N81.8
ICD-10 Finland
Other female genital prolapse
19.8
7.1
10
5
E66.01
ICD-10 Finland
Obesity due to excess calories
2.6
7.1
50
197
99810
ICD-8 Finland
Other complications of surgical procedures, Postoperative haemorrhage or haematoma
6.5
7.0
17
26
A06AD11
ATC
lactulose; oral
1.5
7.0
295
2122
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
3.0
7.0
40
136
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
7.0
400
3057
SPAT1216
SPAT
Assessment of functional ability
1.5
7.0
279
1990
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
7.0
510
4066
G47.3
ICD-10 Finland
Sleep apnoea
1.8
6.8
118
678
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
2.9
6.8
39
133
9271
FHL
Hallux surgery
2.1
6.8
70
330
R19.5
ICD-10 Finland
Other faecal abnormalities
4.0
6.8
25
62
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
2.7
6.8
42
154
J01MA12
ATC
levofloxacin; systemic
1.5
6.7
211
1426
X15
ICPC
Vaginal symptom/complaint other
3.3
6.7
31
93
LEF10
NOMESCO Finland
Colpoperineoplasty
39.6
6.7
8
*
9201
FHL
Anterior decompression surgery (also includes dees)
16.5
6.7
10
6
G04BD11
ATC
fesoterodine; oral
2.4
6.7
53
221
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
6.7
78
390
U05
ICPC
Urination problems other
2.2
6.6
62
282
8112
FHL
Scraping the cervix
22.3
6.6
9
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.6
287
2079
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
6.6
234
1626
359
Kela drug reimbursment
Mirabegroni
5.8
6.5
17
29
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
6.5
564
4607
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
6.5
113
650
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
6.5
205
1388
SPAT1285
SPAT
Provision of consultation response
2.1
6.5
72
352
L13
ICPC
Hip symptom/complaint
1.5
6.4
236
1650
R30.1
ICD-10 Finland
Vesical tenesmus
3.7
6.4
26
71
R30.0
ICD-10 Finland
Dysuria
2.6
6.4
42
160
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
2.2
6.3
60
275
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.2
6.3
30
93
N05CF01
ATC
zopiclone; oral
1.3
6.3
512
4137
A07AA02
ATC
nystatin; oral
1.8
6.2
111
645
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
+∞
6.2
6
*
6200A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Follicular cyst of ovary
+∞
6.2
6
*
6227A
ICD-9 Finland
Noninflammatory disorders of cervix, Mucous polyp of cervix
+∞
6.2
6
*
62130
ICD-8 Finland
Other diseases of cervix, Chronic erosion and ulceration of cervix
+∞
6.2
6
*
LEF06
NOMESCO Finland
Anterior colporraphy with mesh for recurrent cystocele
+∞
6.2
6
*
N84.2
ICD-10 Finland
Polyp of vagina
+∞
6.2
6
*
62551
ICD-8 Finland
NA
+∞
6.2
6
*
6171A
ICD-9 Finland
Endometriosis of ovary
+∞
6.2
6
*
N30.9
ICD-10 Finland
Cystitis, unspecified
1.7
6.2
124
745
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
6.2
296
2181
R05FB02
ATC
cough suppressants and expectorants
1.3
6.2
536
4366
5965D
ICD-9 Finland
Other disorders of bladder, Other functional disorders of bladder[URGE INCONTINENCE]
26.4
6.2
8
*
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.1
6.2
63
296
M01AX01
ATC
nabumetone; oral
2.0
6.2
72
359
R05
ICD-10 Finland
Cough
1.5
6.2
221
1540
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
6.1
133
817
A07DA03
ATC
loperamide; oral
2.3
6.1
55
244
8221
FHL
Sterilization of the laparotomy pathway
2.9
6.1
33
112
L28
ICPC
Limited function/disability (L)
1.4
6.1
282
2068
UJD02
NOMESCO Finland
Gastroscopy
2.1
6.1
67
327
ACC51
NOMESCO Finland
Release of median nerve
1.9
6.1
82
435
B01AB05
ATC
enoxaparin; parenteral
1.4
6.1
401
3129
J01FA09
ATC
clarithromycin; systemic
1.4
6.0
295
2183
A10BA02
ATC
metformin; oral
1.4
6.0
397
3096
J01XX05
ATC
methenamine; oral
2.5
6.0
43
171
E0000UV
ATC
NA
1.3
6.0
457
3644

Mortality – FinRegistry

Association

Association between endpoint N14_PROHERNOV and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_PROHERNOV.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_PROHERNOV – Prolapse and hernia of ovary and fallopian tube

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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