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Chronic lymphocytic leukaemia, helper endpoint

HLP_C3_CLL

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9823
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

969

4. Check minimum number of events

None

969

5. Include endpoints

None

969

6. Filter based on genotype QC (FinnGen only)

969

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Similar endpoints

List of similar endpoints to Chronic lymphocytic leukaemia, helper endpoint based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 969 340 629
Unadjusted period prevalence (%) 0.22 0.12 0.28
Median age at first event (years) 68.70 67.83 69.16

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
878
Matched controls
8781
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
323.0
748
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
160.0
323.0
453
58
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
4503599627370496.0
323.0
776
*
XW000
NOMESCO Finland
Bone marrow biopsy
39.1
248.2
319
126
L03AA02
ATC
filgrastim; parenteral
1110.5
188.8
178
*
A04AA01
ATC
ondansetron; systemic, rectal
55.9
186.2
220
52
JN4BD
NOMESCO Finland
Extensive body CT
15.6
139.1
242
209
L01BB05
ATC
fludarabine; systemic
+∞
137.1
128
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
507.8
134.9
131
*
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
744.4
133.3
128
*
L01AA02
ATC
chlorambucil; oral
+∞
131.6
123
*
M04AA01
ATC
allopurinol; systemic
6.9
127.0
390
906
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
125.0
117
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
14.8
124.0
219
192
L03AA13
ATC
pegfilgrastim; parenteral
+∞
122.8
115
*
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
80.8
122.8
137
20
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
108.6
102
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
61.9
105.8
123
23
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.4
100.8
274
509
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
366.1
98.1
97
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
353.0
94.8
94
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
484.6
89.9
88
*
9823/3-C77.9
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of lymph node, NOS
+∞
86.9
82
*
390
Kela drug reimbursment
Ibrutinib
+∞
85.8
81
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
84.7
80
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
309.9
84.1
84
*
1512
Kela drug reimbursment
Ibrutinib
+∞
80.4
76
*
WW500
NOMESCO Finland
Blood transfusion
20.5
77.5
118
66
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
136.3
71.1
75
6
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
67.6
64
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
67.6
64
*
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
75.3
67.4
76
11
B73
ICPC
Leukaemia
698.3
66.8
65
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
21.1
66.7
100
53
R50.9
ICD-10 Finland
Fever, unspecified
5.3
66.5
232
557
A04AA02
ATC
granisetron; systemic, transdermal
686.6
65.8
64
*
JN4AD
NOMESCO Finland
Body CT examination
11.1
65.1
129
134
399
Kela drug reimbursment
Venetoclax
+∞
64.3
61
*
L01XE27
ATC
[U] ibrutinib; oral
+∞
64.3
61
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
11.2
63.0
124
127
H02AB02
ATC
dexamethasone; systemic
32.6
62.9
83
28
L01AA01
ATC
cyclophosphamide; systemic
120.6
62.8
67
6
ZX120
NOMESCO Finland
Intravenous
6.3
58.9
170
320
A03FA01
ATC
metoclopramide; systemic, rectal
5.0
54.7
196
474
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.9
54.5
201
502
116
Kela drug reimbursment
Prostate cancer
+∞
53.7
51
*
L01XX52
ATC
venetoclax; oral
+∞
53.7
51
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
36.7
53.1
68
20
JN6AD
NOMESCO Finland
CT of torso and neck
119.3
52.4
56
5
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.1
52.2
155
300
1XC02
NOMESCO Finland
NA
54.4
51.5
61
12
J05AB11
ATC
valaciclovir; oral
4.6
51.4
201
530
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
49.8
504
2768
PJA10
NOMESCO Finland
Exploration of lymph nodes
67.5
49.8
57
9
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
49.4
47
*
130
Kela drug reimbursment
Malignant tumour
+∞
48.4
46
*
L01EL01
ATC
ibrutinib; oral
+∞
45.2
43
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
45.2
43
*
1518
Kela drug reimbursment
NA
+∞
42.0
40
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
42.0
40
*
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
+∞
39.9
38
*
ZX108
NOMESCO Finland
Inhalation
42.2
38.8
48
12
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
36.7
35
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
35.6
34
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
34.6
33
*
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
59.7
34.5
40
7
ZX112
NOMESCO Finland
Subcutaneous
35.5
34.3
44
13
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.6
34.3
339
1712
D70.82
ICD-10 Finland
Drug-induced neutropenia
79.4
34.1
38
5
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
33.5
32
*
L57.0
ICD-10 Finland
Actinic keratosis
4.3
33.2
135
359
J01MA12
ATC
levofloxacin; systemic
2.9
32.9
235
970
C90.0
ICD-10 Finland
Multiple myeloma
328.1
32.1
32
*
372
Kela drug reimbursment
Idelalisib
+∞
31.4
30
*
212
Kela drug reimbursment
Gout
7.7
31.1
74
103
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
88.3
30.9
34
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
165.7
30.9
32
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
6.9
30.8
79
123
J01MA14
ATC
moxifloxacin; systemic
3.9
30.4
136
393
115
Kela drug reimbursment
Breast cancer
+∞
30.4
29
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
30.4
29
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.6
29.7
259
1199
L01XX47
ATC
[U] idelalisib; oral
+∞
29.3
28
*
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
29.3
28
*
Z51.5
ICD-10 Finland
Palliative care
8.3
29.2
66
85
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
301.1
28.9
29
*
WF002
NOMESCO Finland
Radical radiotherapy
82.9
28.9
32
*
2041A
ICD-9 Finland
Lymphoid leukaemia, Chronic
+∞
28.3
27
*
L02BB03
ATC
bicalutamide; oral
+∞
28.3
27
*
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
15.0
28.2
47
33
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
66.2
28.1
32
5
WF003
NOMESCO Finland
Adjuvant radiotherapy
103.3
27.8
30
*
L02AE02
ATC
leuprorelin; implant, parenteral
149.6
27.8
29
*
1AA09
NOMESCO Finland
NA
+∞
27.2
26
*
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
77.6
26.9
30
*
D72.9
ICD-10 Finland
Disorder of white blood cells, unspecified
77.6
26.9
30
*
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
99.8
26.8
29
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
26.2
25
*
J05AB01
ATC
aciclovir; systemic
2.7
25.9
212
935
R59.9
ICD-10 Finland
Enlarged lymph nodes, unspecified
31.1
25.1
33
11
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
25.1
24
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
27.1
25.0
34
13
ZZR00
NOMESCO Finland
Flap of skin
20.8
24.5
36
18
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.1
24.5
419
2642
9823/3-C77.8
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of lymph nodes of multiple regions
+∞
24.1
23
*
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
5.3
23.1
72
144
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
23.0
22
*
C91
ICD-10 Finland
Lymphoid leukaemia
+∞
23.0
22
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
23.0
220
1049
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
5.4
22.6
70
139
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.5
22.5
68
131
H02AB06
ATC
prednisolone; systemic
2.0
22.3
439
2893
TQW99
NOMESCO Finland
Other minor procedure on skin
5.3
22.2
70
142
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.3
22.1
60
101
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
8.5
21.9
48
59
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
20.9
20
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
112.6
20.6
22
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
15.5
20.3
33
22
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
20.2
117
407
WW200
NOMESCO Finland
Immunization
7.4
20.1
48
68
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
36.7
19.9
25
7
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
+∞
19.9
19
*
XX3DW
NOMESCO Finland
Time consuming IT work
4.3
19.2
73
181
R23.8
ICD-10 Finland
Other and unspecified skin changes
2.7
19.1
140
570
B01AB10
ATC
tinzaparin; parenteral
4.9
19.1
64
139
B02.9
ICD-10 Finland
Zoster without complication
3.9
19.1
82
227
WZC30
NOMESCO Finland
Teaching
3.1
18.9
112
398
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
18.8
18
*
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
+∞
18.8
18
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
18.8
18
*
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
+∞
18.8
18
*
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
193.8
18.6
19
*
Y77
ICPC
Malignant neoplasm prostate
193.8
18.6
19
*
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
30.8
18.4
24
8
JN4CD
NOMESCO Finland
Very extensive body CT
7.1
17.9
44
65
C91.7
ICD-10 Finland
Other lymphoid leukaemia
+∞
17.8
17
*
L01BC06
ATC
capecitabine; oral
+∞
17.8
17
*
A04AD12
ATC
aprepitant; systemic
+∞
17.8
17
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
17.8
17
*
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
17.8
17
*
L02BG04
ATC
letrozole; oral
96.9
17.6
19
*
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
183.3
17.6
18
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
16.7
16
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.0
16.6
68
181
A02BC02
ATC
pantoprazole; systemic
1.8
16.2
556
4259
TGC00
NOMESCO Finland
Bronchial lavation
5.1
16.2
51
104
6BA02
NOMESCO Finland
NA
48.4
16.1
19
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
+∞
15.7
15
*
JN4ED
NOMESCO Finland
Body CT examination with specail preparation
+∞
15.7
15
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
15.7
15
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
15.7
15
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
86.6
15.6
17
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.6
15.5
72
213
N02AA05
ATC
oxycodone; systemic
2.5
15.4
130
570
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
38.8
15.4
19
5
A41.9
ICD-10 Finland
Sepsis, unspecified
4.1
15.3
60
153
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
14.9
276
1705
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.1
14.8
47
97
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
7.0
14.8
36
53
HAB40
NOMESCO Finland
Wedge excision of mammary gland
25.5
14.7
20
8
H02AB07
ATC
prednisone; oral
2.3
14.7
153
744
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
14.6
14
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
14.6
14
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
14.6
14
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
27.7
14.3
19
7
A79
ICPC
Malignancy NOS
43.2
14.1
17
*
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
12.9
13.9
24
19
ZX070
NOMESCO Finland
Intensity modified radiotherapy
76.3
13.6
15
*
C90.1
ICD-10 Finland
Plasma cell leukaemia
+∞
13.6
13
*
1CX01
NOMESCO Finland
NA
+∞
13.6
13
*
B74
ICPC
Malignant neoplasm blood other
142.0
13.5
14
*
J02AC03
ATC
voriconazole; systemic
142.0
13.5
14
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
13.4
254
1569
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
11.7
13.3
24
21
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.4
13.3
117
523
B01AB05
ATC
enoxaparin; parenteral
1.9
13.3
252
1559
J01DB01
ATC
cefalexin; oral
1.8
13.3
656
5449
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
7.1
12.9
31
45
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
70.8
12.6
14
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
12.5
12
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
12.5
12
*
8070/3-C44.3
ICD-O-3
Squamous cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
12.5
12
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.7
12.3
84
327
J01CA04
ATC
amoxicillin; systemic
1.7
12.3
624
5152
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.1
12.1
47
120
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
27.1
12.1
16
6
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.1
12.0
46
116
ZXC50
NOMESCO Finland
Cryotherapy
4.9
11.9
38
80
HA1AA
NOMESCO Finland
X-ray mammography
5.0
11.8
37
76
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
65.8
11.6
13
*
8097/3-C44.9
ICD-O-3
Basal cell carcinoma, nodular of skin, NOS
+∞
11.5
11
*
C83.0
ICD-10 Finland
Small cell B-cell lymphoma
+∞
11.5
11
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
11.5
11
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
11.5
11
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
11.5
11
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
121.4
11.4
12
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
121.4
11.4
12
*
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
4.8
11.4
37
79
D06BB10
ATC
imiquimod; topical
3.9
11.4
46
122
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
6.0
11.3
30
51
PJD45
NOMESCO Finland
Excision of inguinal lymph nodes
43.8
10.9
13
*
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.4
10.7
89
386
L02BA01
ATC
tamoxifen; oral
60.7
10.6
12
*
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
10.6
46
130
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
111.2
10.4
11
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
10.4
10
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
10.4
10
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
10.4
10
*
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
+∞
10.4
10
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
10.4
10
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
10.4
10
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
+∞
10.4
10
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
6.9
10.4
25
37
L04.0
ICD-10 Finland
Acute lymphadenitis of face, head and neck
23.6
10.3
14
6
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
10.2
193
1177
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.3
10.2
30
58
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
10.1
75
308
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
7.3
10.0
23
32
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
4.1
10.0
38
96
S77
ICPC
Malignant neoplasm of skin
40.5
10.0
12
*
B02
ICPC
Lymph gland(s) enlarged/painful
20.3
9.8
14
7
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
20.3
9.8
14
7
B03XA01
ATC
erythropoietin; parenteral
8.9
9.8
20
23
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.3
9.8
89
404
S18
ICPC
Laceration/cut
1.6
9.8
349
2556
WX892
NOMESCO Finland
Monitored bed care
2.4
9.7
80
345
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
5.3
9.6
28
54
C50
ICD-10 Finland
Malignant neoplasm of breast
101.0
9.4
10
*
ZX080
NOMESCO Finland
Image guided radiotherapy
101.0
9.4
10
*
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
101.0
9.4
10
*
C44.42
ICD-10 Finland
Spinocellular carcinoma of the skin of the scalp and neck
101.0
9.4
10
*
NK6AN
NOMESCO Finland
Total body bone isotope imaging
30.3
9.4
12
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.5
9.4
32
73
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
9.4
9
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
9.4
9
*
X76
ICPC
Malignant neoplasm breast female
+∞
9.4
9
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
9.4
9
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
9.4
9
*
C44.20
ICD-10 Finland
Malignant tumor of the skin of the outer ear and of the outer ear canal without histology
+∞
9.4
9
*
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
+∞
9.4
9
*
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
+∞
9.4
9
*
B72
ICPC
Hodgkin Lymphoma
+∞
9.4
9
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
9.3
89
415
ZXC15
NOMESCO Finland
Use of photodynamic technique
7.8
9.2
20
26
A03
ICPC
Fever
2.2
9.0
98
482
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.3
8.9
44
140
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
3.5
8.8
40
119
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.3
8.7
43
136
WX402
NOMESCO Finland
General anaesthesia
2.1
8.7
102
518
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
50.4
8.7
10
*
R4190
NOMESCO Finland
Nutritional therapy
5.3
8.6
25
48
R4110
NOMESCO Finland
Physiotherapy
1.7
8.5
204
1331
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
27.8
8.5
11
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
90.8
8.4
9
*
122
Kela drug reimbursment
Aplastic anaemia
90.8
8.4
9
*
B99
ICPC
Blood/lymph/spleen disease other
12.9
8.4
14
11
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
8.3
8
*
D04.8
ICD-10 Finland
Carcinoma in situ: Skin of other sites
+∞
8.3
8
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
8.3
8
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
8.3
8
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
8.3
8
*
CBB50
NOMESCO Finland
Excision of lesion of eyelid and reconstruction using graft or flap
+∞
8.3
8
*
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
+∞
8.3
8
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
8.3
8
*
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
+∞
8.3
8
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
8.3
8
*
C83.01
ICD-10 Finland
Lymphoplasmacytic lymphoma
+∞
8.3
8
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
8.3
8
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
8.3
8
*
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
9.6
8.3
16
17
S29
ICPC
Skin symptom/complaint other
1.8
8.2
138
805
WX110
NOMESCO Finland
Local anesthesy
1.5
8.2
473
3820
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
14.6
8.2
13
9
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
8.2
8.1
17
21
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
22.2
8.0
11
5
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
22.2
8.0
11
5
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.5
7.8
60
250
D80.8
ICD-10 Finland
Other immunodeficiencies with predominantly antibody defects
45.3
7.7
9
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
45.3
7.7
9
*
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
4.6
7.6
25
56
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.8
7.6
129
754
J12.8
ICD-10 Finland
Other viral pneumonia
8.9
7.6
15
17
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.7
7.5
24
52
3AA02
NOMESCO Finland
NA
80.7
7.4
8
*
C50.99
ICD-10 Finland
Breast, unspecified
80.7
7.4
8
*
ZQZ00
NOMESCO Finland
Treatment of several skin areas
80.7
7.4
8
*
B59
ICD-10 Finland
Pneumocystosis
80.7
7.4
8
*
B03XA02
ATC
darbepoetin alfa; parenteral
4.6
7.4
24
53
KCD02
NOMESCO Finland
Transurethral resection of bladder
8.4
7.3
15
18
DAB00
NOMESCO Finland
Excision of lesion of auricle
11.0
7.3
13
12
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
7.3
7
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
+∞
7.3
7
*
C44.91
ICD-10 Finland
Unspecified localization of basocellular carcinoma of the skin
+∞
7.3
7
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
7.3
7
*
9823/3-C77.0
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of lymph nodes of head, face and neck
+∞
7.3
7
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
7.3
7
*
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
+∞
7.3
7
*
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
7.3
7
*
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
7.3
7
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
+∞
7.3
7
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
7.3
7
*
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
+∞
7.3
7
*
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.3
320
2418
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
7.2
124
730
DAB10
NOMESCO Finland
Partial excision of auricle
30.2
7.2
9
*
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
2.8
6.9
41
149
EBA10
NOMESCO Finland
Surgical removal of tooth
2.2
6.9
67
315
J35.1
ICD-10 Finland
Hypertrophy of tonsils
8.3
6.8
14
17
ZXC20
NOMESCO Finland
Use of chemical agents
4.6
6.8
22
49
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
6.8
88
466
B01.9
ICD-10 Finland
Varicella without complication
40.3
6.8
8
*
EMA10
NOMESCO Finland
Biopsy of tonsil
40.3
6.8
8
*
ZZA50
NOMESCO Finland
Full thickness skin graft
40.3
6.8
8
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
6.7
64
298
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
6.7
122
732
R06AE07
ATC
cetirizine; oral
1.5
6.6
284
2124
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.2
6.6
32
102
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.4
6.6
52
221
A02BC01
ATC
omeprazole; systemic
1.5
6.5
236
1703
L02BG03
ATC
anastrozole; oral
70.3
6.4
7
*
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.7
6.4
26
72
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
8.2
6.3
13
16
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
18.1
6.3
9
5
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
6.3
6
*
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
+∞
6.3
6
*
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
+∞
6.3
6
*
8090/3-C44.6
ICD-O-3
Basal cell carcinoma, NOS, of skin of upper limb and shoulder
+∞
6.3
6
*
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
+∞
6.3
6
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
6.3
6
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
+∞
6.3
6
*
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
6.3
6
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
6.3
6
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
6.3
6
*
C67.2
ICD-10 Finland
Malignant neoplasm: Lateral wall of bladder
+∞
6.3
6
*
8090/3-C44.2
ICD-O-3
Basal cell carcinoma, NOS, of external ear
+∞
6.3
6
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
6.3
6
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
+∞
6.3
6
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
6.3
6
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
6.3
6
*
C95.1
ICD-10 Finland
Chronic leukaemia of unspecified cell type
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
26.8
6.2
8
*
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
6.2
101
584
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.4
6.1
50
218
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.2
6.1
55
253

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
230
84
35.59
307.65
8.1
3.0
0.23
1.47
%
1.80
184
59
504
442
22.68
307.65
4.4
2.1
7.81
11.02
g/l
25.05
481
404
315
201
22.74
307.65
1.7
1.2
—
—
—
0
0
601
1017
13.93
307.65
8.2
2.1
1.75
1.79
%
0.38
567
884
383
190
32.68
307.65
2.8
1.4
—
—
—
0
0
510
768
12.91
307.65
9.2
2.3
71.08
67.57
e9/l
1.13
398
597
253
110
30.77
307.65
1.5
1.5
—
—
—
0
0
245
53
61.53
307.65
1.5
1.1
—
—
—
0
0
301
284
14.92
292.34
1.3
1.4
—
—
—
0
0
320
386
11.88
261.45
3.4
1.6
1.23
1.53
g/l
5.08
282
329
363
556
9.84
245.10
10.9
3.6
0.16
0.75
%
7.41
271
129
339
486
10.19
241.30
1.4
1.4
—
—
—
0
0
710
2311
8.75
231.14
20.1
5.2
—
—
—
0
0
289
358
11.08
229.69
2.0
1.3
1.15
1.19
g/l
0.06
249
330
115
15
86.86
217.33
1.2
1.0
—
—
—
0
0
319
486
9.29
214.07
1.4
1.5
—
—
—
0
0
344
582
8.61
210.55
1.4
1.5
—
—
—
0
0
319
506
8.91
206.26
11.1
3.6
0.13
0.56
%
2.21
210
96
322
531
8.58
200.85
11.6
3.7
0.06
0.06
%
0.04
266
117
151
77
23.05
199.90
1.1
1.1
—
—
—
0
0
785
3179
8.74
191.41
18.9
5.4
1.58
3.00
%
69.42
759
2913
786
3190
8.75
191.09
20.7
5.6
6.06
8.96
%
63.36
759
2933
786
3243
8.54
185.83
19.7
5.5
54.99
26.21
%
143.26
758
2963
764
3088
7.97
184.03
17.9
5.3
0.41
0.67
%
31.97
738
2832
149
93
18.75
179.33
1.1
1.3
—
—
—
0
0
131
66
22.79
173.81
8.1
3.0
28.95
56.50
%
9.00
76
44
599
2052
6.03
170.15
9.6
2.6
765.83
8111.41
umol/l
7.07
571
1715
759
3217
7.27
167.70
16.7
5.4
35.40
58.40
%
132.77
729
2960
104
32
36.29
164.08
2.5
2.4
1.38
0.95
e9/l
1.32
58
18
282
503
7.50
161.08
11.0
3.8
0.05
0.85
%
0.46
221
103
124
67
21.08
159.32
12.2
3.3
—
—
—
0
0
102
34
33.41
157.01
2.7
2.1
23.92
42.39
%
2.44
24
12
96
27
39.36
155.17
2.6
1.5
542.31
1059.18
e6/l
1.36
36
11
99
33
33.30
152.32
2.2
2.2
—
—
—
0
0
96
33
32.18
146.20
1.1
1.1
—
—
—
0
0
122
79
17.52
143.48
1.1
1.4
106.16
106.87
u/ml
—
19
9
736
3429
5.77
133.36
14.8
5.1
0.74
0.62
e9/l
4.06
667
2917
738
3448
5.78
133.19
14.8
5.1
0.07
0.04
e9/l
0.78
669
2944
751
3570
5.91
132.32
19.1
5.2
0.17
0.21
e9/l
8.35
692
3084
301
691
5.87
130.67
2.3
1.6
63.94
66.94
g/l
6.26
286
616
740
3499
5.72
130.55
15.5
5.2
12.56
1.81
e9/l
31.06
686
3035
776
3829
6.15
129.42
29.9
5.9
3.40
4.47
e9/l
38.77
733
3286
78
21
40.31
127.18
2.7
2.5
2.89
0.18
e9/l
1.66
73
21
746
3598
5.66
126.97
15.2
3.8
12.32
12.50
umol/l
0.18
729
3356
70
13
57.96
123.94
1.2
1.0
—
—
—
0
0
128
117
12.45
123.02
1.2
1.2
—
—
—
0
0
269
609
5.73
117.56
2.1
1.5
—
—
—
0
0
74
25
31.96
112.90
1.8
2.8
10.19
14.38
%
—
21
8
134
150
10.21
111.67
1.3
1.2
—
—
—
0
0
346
1010
4.77
111.09
8.6
4.6
1.08
1.02
mmol/l
4.77
332
915
106
88
13.40
107.94
1.2
1.2
360.56
278.45
u/ml
0.96
52
44
185
317
6.98
107.36
2.1
1.4
2.98
3.12
g/l
1.00
158
247
191
346
6.63
104.87
2.1
1.4
6.68
7.45
g/l
6.27
158
250
191
346
6.63
104.87
2.1
1.4
3.09
3.95
g/l
6.51
158
245
95
69
15.16
104.51
1.3
1.1
—
—
—
0
0
166
275
7.08
99.17
2.1
1.3
39.24
37.30
g/l
3.07
156
227
181
328
6.56
99.09
2.1
1.4
8.28
10.62
g/l
7.51
163
273
338
1080
4.27
94.41
3.5
2.4
0.82
0.82
mmol/l
0.05
321
984
510
2204
3.77
91.09
7.6
4.1
—
—
—
0
0
337
1108
4.13
89.92
1.8
1.3
1.69
2.90
g/l
8.88
282
631
51
14
38.40
82.25
1.7
3.3
—
—
—
0
0
471
2053
3.52
80.63
3.1
1.7
—
—
—
0
0
399
1587
3.57
78.61
21.8
4.5
—
—
—
0
0
367
1388
3.65
78.14
15.3
4.1
—
—
—
0
0
684
3809
3.71
77.85
13.3
5.5
1.21
1.21
mmol/l
0.38
598
3195
242
705
4.24
74.91
4.5
2.3
8.81
9.31
umol/l
0.09
229
611
479
2198
3.33
73.83
9.8
3.1
7.40
7.40
ph
0.37
76
377
634
3489
3.36
70.90
11.8
5.1
1.21
1.21
mmol/l
0.06
604
3061
597
3201
3.25
69.18
7.0
3.8
34.74
35.03
g/l
0.52
568
2931
61
44
14.73
66.96
2.9
1.7
—
—
—
0
0
286
1031
3.52
63.88
2.8
2.5
23.24
22.85
%
0.16
251
860
182
483
4.41
63.07
1.7
1.1
—
—
—
0
0
43
17
26.42
61.76
1.5
1.3
—
—
—
0
0
566
3077
3.02
61.48
25.9
8.7
0.00
0.00
e9/l
0.21
485
2491
292
1099
3.37
60.49
2.7
2.4
2.23
2.25
g/l
0.16
278
1007
430
2082
2.92
56.67
5.5
2.2
—
—
—
0
0
36
11
33.95
56.06
2.1
1.0
—
—
—
0
0
68
79
9.18
54.41
1.8
1.4
—
—
—
0
0
68
79
9.18
54.41
1.8
1.4
—
—
—
0
0
68
79
9.18
54.41
1.8
1.4
—
—
—
0
0
68
79
9.18
54.41
1.8
1.4
—
—
—
0
0
298
1205
3.13
53.96
2.8
2.3
13.27
12.73
umol/l
0.52
285
1091
801
5564
3.54
51.72
21.3
5.4
83.22
77.92
u/l
2.84
778
5091
71
96
7.90
50.19
1.1
1.1
—
—
—
0
0
37
19
20.21
47.80
1.6
1.0
—
—
—
0
0
84
146
6.20
47.00
1.4
1.1
120.39
18.42
u/l
1.45
76
129
117
274
4.72
46.98
2.1
1.5
31.47
55.32
mg/l
0.59
107
222
359
1712
2.74
46.89
6.2
3.6
83.15
81.56
%
0.56
351
1660
117
275
4.70
46.76
2.2
1.5
62.56
48.37
mg/l
0.75
108
222
536
3146
2.57
45.20
7.9
3.7
—
—
—
0
0
66
93
7.54
44.96
1.1
1.1
—
—
—
0
0
129
348
4.12
43.04
2.3
1.7
1.02
1.69
ug/l
0.63
113
300
95
201
5.13
42.95
1.9
1.4
—
—
—
0
0
339
1642
2.64
42.12
4.8
2.1
—
—
—
0
0
70
114
6.54
41.70
8.3
2.9
30.13
59.64
%
19.12
70
114
62
90
7.29
41.10
1.1
1.0
—
—
—
0
0
479
2830
2.37
37.57
3.9
2.7
451.61
150.37
ug/l
1.58
440
2540
378
2039
2.40
36.20
2.7
2.2
4.06
2.96
mg/l
6.18
332
1696
132
408
3.59
36.01
3.4
1.4
8.55
3.70
ug/l
0.58
100
305
59
96
6.48
35.12
1.6
1.5
30.53
25.93
g/l
1.63
53
86
267
1242
2.59
35.12
2.3
1.8
29.40
30.05
s
0.95
257
1198
132
425
3.44
33.73
4.5
3.1
4.07
4.29
e9/l
0.24
87
294
653
4546
2.34
33.10
7.1
4.4
6.83
6.94
mmol/l
0.65
639
4256
414
2397
2.27
32.86
4.8
2.1
2.34
2.35
mmol/l
0.69
365
1933
398
2282
2.26
32.18
3.8
3.1
43.08
91.52
e6/l
0.93
325
1765
199
837
2.73
31.75
1.6
1.4
—
—
—
0
0
233
1083
2.52
30.18
2.1
2.0
—
—
—
0
0
32
32
10.31
28.39
2.0
1.8
5707.31
1327.41
u/ml
1.77
32
32
50
88
5.94
27.49
1.7
1.5
1952.61
1711.25
e6/l
0.15
41
61
53
100
5.55
27.09
2.7
2.6
—
—
—
0
0
47
79
6.20
27.06
1.7
1.6
91998.03
112832.13
e6/l
0.08
31
45
358
2090
2.13
26.51
3.7
3.0
0.38
0.53
e6/l
0.88
289
1583
717
5450
2.21
25.69
6.4
4.1
13.96
13.36
mm/h
0.35
675
4947
164
692
2.65
25.63
5.9
5.6
10.73
11.26
mmol/l
0.41
156
649
419
2623
2.05
25.48
4.5
3.5
77.92
97.51
e6/l
0.42
335
1884
339
1997
2.07
24.03
3.8
3.0
—
—
—
0
0
287
1602
2.12
23.38
3.2
2.4
3.94
4.62
e6/l
0.69
254
1396
39
64
6.31
22.97
1.8
1.5
—
—
—
0
0
272
1497
2.14
22.92
3.5
2.6
537.21
554.45
mosm/kgh2o
0.77
242
1250
41
76
5.59
21.34
1.6
1.5
—
—
—
0
0
644
4881
1.95
20.77
5.5
4.5
880.33
1791.11
e6/l
0.38
12
76
340
2103
1.95
20.31
1.9
1.6
20.83
20.45
nmol/l
0.17
310
1745
336
2070
1.95
20.31
5.8
2.6
37.47
35.09
u/l
0.33
325
1955
40
76
5.45
20.27
1.7
1.6
—
—
—
0
0
36
67
5.54
18.65
1.2
1.2
171.17
142.09
miu/ml
—
6
19
16
10
16.25
18.54
1.1
1.1
—
—
—
0
0
171
848
2.23
18.34
1.8
1.7
—
—
—
0
0
131
582
2.45
18.09
1.8
1.9
0.19
0.19
g/l
0.22
118
516
144
673
2.34
17.74
8.7
6.8
—
—
—
0
0
217
1195
2.05
17.71
3.1
2.8
1.71
2.02
e6/l
0.28
126
650
27
40
6.91
17.48
1.7
1.3
—
—
—
0
0
64
198
3.39
17.23
1.2
1.4
—
—
—
0
0
471
3369
1.77
16.80
11.4
11.2
1.30
1.40
inr
1.42
127
927
24
33
7.43
16.58
11.0
1.2
202.00
204.45
u/l
0.07
24
33
248
1468
1.93
16.31
1.8
1.6
1.90
1.28
mg/l
1.00
206
1136
125
575
2.35
15.90
2.1
2.1
34.19
33.84
u/l
0.04
115
460
270
1657
1.87
15.83
3.8
4.2
338.72
491.93
ng/l
0.42
235
1428
486
3548
1.74
15.80
2.6
2.1
93.83
92.61
pmol/l
0.22
303
1830
38
87
4.51
15.55
1.2
1.6
0.30
1.08
g/l
3.20
30
67
141
695
2.20
15.20
8.0
6.1
1.11
1.49
mmol/l
6.40
136
670
112
521
2.30
13.84
4.3
3.6
7.44
7.41
ph
1.59
15
60
113
530
2.28
13.69
4.3
3.5
4.99
5.15
kpa
1.23
99
486
178
995
1.97
13.63
9.1
6.0
104.25
104.37
mmol/l
0.13
171
969
237
1455
1.83
13.61
4.3
2.2
2.45
2.45
mmol/l
0.07
215
1241
26
49
5.42
13.30
1.3
1.2
—
—
—
0
0
17
20
8.63
13.28
1.5
1.5
—
—
—
0
0
43
122
3.64
13.21
2.0
2.3
—
—
—
0
0
216
1300
1.85
13.17
3.1
2.6
0.92
1.39
e6/l
0.76
125
750
28
58
4.94
12.91
1.3
1.2
7.13
7.48
g/l
0.08
23
42
28
58
4.94
12.91
1.3
1.2
1.52
2.86
g/l
3.90
23
42
28
58
4.94
12.91
1.3
1.2
0.29
0.40
g/l
0.75
22
42
71
279
2.67
12.58
1.4
1.2
—
—
—
0
0
27
57
4.84
12.18
1.3
1.2
—
—
—
0
0
389
2812
1.64
12.11
3.0
3.0
1902.06
1668.35
ng/l
0.48
355
2422
255
1656
1.73
11.89
1.3
1.3
—
—
—
0
0
51
173
3.06
11.84
1.4
1.2
—
—
—
0
0
30
72
4.27
11.59
1.6
1.3
—
—
—
0
0
624
5097
1.63
11.55
5.1
4.3
—
—
—
0
0
57
211
2.81
11.33
2.6
3.1
24.63
25.04
mmol/l
0.27
45
183
167
976
1.86
11.03
8.0
6.5
1.15
1.23
mmol/l
0.11
133
751
155
888
1.89
10.88
8.5
6.6
93.96
95.11
%
0.82
150
853
28
68
4.21
10.67
1.1
1.3
—
—
—
0
0
812
7175
1.81
10.50
41.8
14.5
26.35
26.16
mg/l
0.06
751
5679
16
24
6.76
10.20
1.1
1.8
—
—
—
0
0
14
18
7.88
10.16
1.6
1.4
—
—
—
0
0
164
979
1.81
10.06
8.5
6.5
4.91
5.08
kpa
1.30
158
934
55
214
2.66
9.96
3.7
3.6
—
—
—
0
0
163
979
1.80
9.79
8.5
6.4
11.32
11.41
kpa
0.07
157
932
111
592
1.99
9.60
1.9
1.7
421.66
362.30
nmol/l
2.42
104
528
325
2352
1.57
9.54
3.5
3.3
—
—
—
0
0
30
86
3.57
9.13
2.5
1.8
19.83
61.55
u/ml
0.99
25
77
140
820
1.83
9.10
3.7
3.1
2.06
2.08
mmol/l
0.01
110
659
47
177
2.74
9.08
2.7
2.8
7.62
7.80
kpa
0.36
38
162
18
36
5.08
8.64
1.1
1.1
—
—
—
0
0
261
1835
1.58
8.52
2.0
1.8
1161.12
1173.54
nmol/l
0.07
201
1366
13
19
6.92
8.46
1.3
1.1
—
—
—
0
0
8
0
+∞
8.34
1.3
0.0
—
—
—
0
0
17
34
5.07
8.16
1.7
1.1
—
—
—
0
0
84
431
2.04
8.08
9.9
9.2
—
—
—
0
0
310
2287
1.52
8.08
2.4
2.3
55.66
58.70
u/l
0.67
285
2083
140
849
1.76
8.07
2.6
3.1
234.19
244.74
ng/l
0.11
124
788
661
5685
1.51
8.02
50.4
17.4
14.67
13.78
%
34.02
653
5520
78
392
2.08
7.94
5.1
3.6
—
—
—
0
0
513
4216
1.46
7.67
3.1
3.0
52.82
52.32
u/l
0.04
466
3789
11
6
18.52
7.61
1.2
1.0
—
—
—
0
0
42
165
2.62
7.51
2.9
2.3
13.36
16.06
%
2.23
19
81
16
33
4.91
7.42
1.1
1.0
—
—
—
0
0
62
293
2.19
7.39
2.3
1.8
—
—
—
0
0
22
59
3.79
7.38
1.1
1.1
—
—
—
0
0
11
16
6.94
7.16
1.2
1.1
176.84
1.37
ug/l
—
6
6
14
27
5.25
6.98
1.4
1.1
—
—
—
0
0
129
797
1.71
6.94
8.6
3.6
—
—
—
0
0
370
2922
1.43
6.52
2.1
2.2
83.88
79.09
nmol/l
2.47
327
2496
17
42
4.10
6.37
1.1
1.1
—
—
—
0
0
10
15
6.73
6.32
1.0
1.1
—
—
—
0
0
64
327
2.02
6.27
1.4
1.3
—
—
—
0
0
64
330
2.01
6.11
5.4
3.9
25.30
24.78
mmol/l
0.69
57
300
693
6169
1.43
5.87
42.5
16.2
37.42
39.14
%
4.32
451
3724
144
961
1.59
5.71
1.3
1.2
—
—
—
0
0
36
151
2.44
5.69
2.9
2.6
—
—
—
0
0
17
46
3.74
5.66
1.2
1.1
—
—
—
0
0
28
104
2.74
5.63
2.4
1.7
89.26
89.82
%
0.25
28
104
17
47
3.66
5.50
1.2
1.1
—
—
—
0
0
43
199
2.21
5.45
2.9
1.5
1.10
1.14
g/l
0.31
43
191
8
5
16.12
5.41
2.0
1.6
1.63
2.20
%
—
8
5
21
68
3.13
5.36
1.3
1.0
—
—
—
0
0
19
61
3.16
4.93
2.6
3.7
—
—
—
0
0
36
164
2.24
4.77
4.0
3.4
—
—
—
0
0
25
96
2.65
4.75
4.0
6.9
10.63
12.41
mg/l
1.05
17
91
38
179
2.17
4.65
2.5
2.1
107.69
131.24
g/l
4.04
26
135
121
825
1.53
4.36
1.5
1.3
586.67
605.77
titre
0.03
24
201
101
661
1.59
4.35
1.2
1.3
—
—
—
0
0
42
212
2.03
4.32
1.1
1.2
—
—
—
0
0
10
22
4.58
4.31
2.1
2.2
—
—
—
0
0
174
1289
1.43
4.14
23.7
30.9
1.51
1.46
inr
0.15
33
181
12
33
3.67
3.93
1.1
1.2
—
—
—
0
0
92
604
1.58
3.93
7.2
2.5
1.22
1.22
mmol/l
0.47
87
501
90
595
1.57
3.74
4.7
4.7
—
—
—
0
0
35
175
2.04
3.73
5.2
4.0
2.14
2.61
mmol/l
0.45
26
114
9
16
5.67
3.66
1.2
1.2
—
—
—
0
0
9
17
5.33
3.51
1.8
2.0
—
—
—
0
0
95
654
1.50
3.30
1.9
2.1
215.78
186.74
ug/g
0.17
75
507
18
72
2.53
3.22
1.1
1.2
1.83
7.17
u/ml
—
6
35
10
28
3.60
3.20
1.1
1.1
—
—
—
0
0
8
15
5.37
3.19
1.0
1.0
—
—
—
0
0
59
369
1.64
3.11
1.4
1.2
24.45
253.23
u/ml
9.60
39
335
40
226
1.80
3.03
3.5
3.3
0.78
0.81
nmol/l
0.12
26
176
44
257
1.75
2.99
3.2
2.5
0.40
0.25
g/l
0.69
26
81
810
7673
1.34
2.87
27.7
9.4
24.05
25.48
u/l
2.11
792
7274
20
90
2.25
2.81
1.4
1.5
—
—
—
0
0
8
18
4.47
2.80
8.1
1.5
—
—
—
0
0
814
7725
1.34
2.78
39.8
17.9
139.44
139.73
mmol/l
2.11
798
7487
411
3609
1.24
2.76
3.9
3.7
0.00
0.00
estimate
0.00
83
609
170
2121
0.76
2.71
3.0
3.4
—
—
—
0
0
15
60
2.52
2.71
1.4
1.5
173.87
68.03
pmol/l
0.67
15
60
15
60
2.52
2.71
1.2
1.1
—
—
—
0
0
20
92
2.20
2.68
1.2
1.3
15.67
6.37
u/l
1.92
14
75
814
7741
1.32
2.61
43.4
18.0
4.04
4.01
mmol/l
2.74
795
7492
381
3336
1.23
2.58
4.2
4.1
172.43
72.37
ng/l
0.33
313
2563
8
20
4.02
2.57
1.0
1.9
—
—
—
0
0
69
471
1.50
2.54
1.9
2.3
11.04
15.30
nmol/l
3.11
55
410
408
3605
1.23
2.52
5.4
5.0
0.00
0.00
estimate
0.00
87
606
7
16
4.40
2.47
1.1
1.1
—
—
—
0
0
669
7118
0.81
2.45
4.4
4.9
1.26
1.42
mmol/l
16.30
595
6401
17
77
2.23
2.38
1.1
1.2
—
—
—
0
0
12
46
2.63
2.36
1.3
1.5
—
—
—
0
0
25
133
1.90
2.33
1.2
1.1
—
—
—
0
0
13
53
2.47
2.28
2.3
2.1
—
—
—
0
0
410
3657
1.21
2.24
3.9
3.8
0.04
0.01
estimate
0.40
85
591
6
14
4.31
2.15
1.2
1.1
—
—
—
0
0
681
7200
0.82
2.14
4.4
4.9
4.27
4.41
mmol/l
2.59
608
6522
5
10
5.02
2.07
1.2
1.1
—
—
—
0
0
6
15
4.02
2.04
1.2
1.2
—
—
—
0
0
84
623
1.38
2.03
3.0
3.6
79.00
93.80
ng/l
1.50
72
534
46
304
1.54
2.01
1.5
1.9
—
—
—
0
0
703
7387
0.82
1.93
5.0
5.6
2.56
2.55
mmol/l
0.12
625
6672
667
7037
0.83
1.87
6.0
6.7
39.06
41.19
mmol/mol
8.01
591
6416
9
34
2.66
1.86
2.1
4.0
—
—
—
0
0
5
12
4.18
1.82
2.8
1.2
—
—
—
0
0
5
13
3.86
1.71
2.2
1.3
—
—
—
0
0
11
48
2.31
1.71
1.8
1.7
12.73
15.11
umol/l
0.56
11
43
16
83
1.94
1.65
1.6
1.3
—
—
—
0
0
76
578
1.34
1.61
4.5
4.0
—
—
—
0
0
60
441
1.38
1.58
1.3
1.2
—
—
—
0
0
11
50
2.21
1.57
1.0
1.3
—
—
—
0
0
292
2596
1.18
1.55
1.8
2.2
153.28
279.01
u/l
1.86
268
2423
657
6899
0.85
1.54
4.0
4.4
1.31
1.29
mmol/l
0.36
584
6140
7
27
2.60
1.51
1.4
1.4
—
—
—
0
0
0
44
0.00
1.51
0.0
3.1
—
—
—
0
0
28
178
1.59
1.50
1.4
1.4
235.57
295.81
ug/g
0.93
19
107
28
179
1.58
1.47
1.1
1.1
—
1892.86
—
0
7
42
295
1.44
1.44
2.3
3.0
4.10
4.41
pmol/l
1.55
34
246
16
88
1.83
1.42
1.6
1.2
0.69
0.67
nmol/l
0.08
16
81
14
74
1.90
1.39
1.1
1.3
—
—
—
0
0
5
17
2.95
1.36
1.4
1.1
—
—
—
0
0
817
7912
1.21
1.35
59.4
21.3
124.12
135.46
g/l
60.08
804
7728
0
37
0.00
1.34
0.0
1.2
—
141.63
—
0
37
0
38
0.00
1.34
0.0
3.2
—
—
—
0
0
176
2030
0.84
1.34
1.6
1.6
1.42
1.33
mmol/l
0.66
147
1654
816
7910
1.20
1.28
58.8
21.1
30.55
30.54
pg
0.03
803
7726
816
7910
1.20
1.28
59.2
21.2
190.52
237.43
e9/l
54.36
800
7620
816
7910
1.20
1.28
58.9
21.1
93.51
91.79
fl
16.54
803
7726
5
18
2.79
1.28
1.0
1.1
—
—
—
0
0
816
7911
1.20
1.28
59.1
21.2
4.13
4.46
e12/l
42.93
798
7588
816
7912
1.20
1.27
59.2
21.2
20.85
6.87
e9/l
42.57
797
7591
567
5355
1.14
1.25
4.7
4.3
—
—
—
0
0
6
25
2.41
1.24
2.5
1.8
—
—
—
0
0
10
49
2.05
1.22
2.7
3.3
—
—
—
0
0
8
37
2.17
1.21
1.3
1.4
—
1819.30
—
0
10
10
50
2.01
1.16
1.0
1.3
—
—
—
0
0
5
20
2.51
1.15
1.6
2.7
—
—
—
0
0
87
1057
0.81
1.14
1.2
1.2
26.94
14.31
u/ml
0.32
19
356
228
2039
1.15
1.11
2.8
2.8
0.79
0.77
ug/l
0.09
170
1428
609
5805
1.13
1.10
53.0
19.6
326.90
332.21
g/l
28.21
603
5754
204
1813
1.16
1.08
4.1
3.5
—
—
—
0
0
38
279
1.38
1.07
4.0
4.2
3.92
3.93
mmol/l
0.04
33
261
10
52
1.93
1.06
1.0
1.3
—
—
—
0
0
10
52
1.93
1.06
1.0
1.3
—
—
—
0
0
43
325
1.34
1.02
4.0
3.9
1.24
1.47
mmol/l
0.85
43
318
270
2458
1.14
1.01
4.5
4.2
—
—
—
0
0
57
714
0.79
0.99
1.6
1.5
—
—
—
0
0
9
49
1.84
0.98
1.0
1.3
—
—
—
0
0
17
260
0.65
0.98
2.2
2.4
90.42
64.17
ug/min
—
9
153
7
36
1.95
0.97
1.0
1.7
—
—
—
0
0
393
3671
1.12
0.96
4.9
4.0
10.39
2.15
ug/l
0.51
352
3271
9
51
1.77
0.94
1.0
1.3
—
—
—
0
0
7
37
1.90
0.94
3.6
2.2
—
—
—
0
0
203
1824
1.14
0.93
3.5
3.6
—
—
—
0
0
26
184
1.42
0.92
1.0
1.1
—
—
—
0
0
6
28
2.15
0.91
2.3
2.2
—
—
—
0
0
708
7303
0.89
0.91
5.6
5.1
6.05
6.14
mmol/l
1.39
639
6489
8
42
1.91
0.88
1.0
1.4
—
—
—
0
0
17
111
1.54
0.88
2.7
2.3
—
—
—
0
0
10
56
1.79
0.88
1.2
1.3
—
—
—
0
0
6
31
1.94
0.84
1.2
2.0
2408.33
2213.85
ml
—
6
26
22
154
1.44
0.84
1.2
1.3
6.12
60.45
e6/l
0.84
16
127
6
113
0.53
0.83
1.8
2.8
—
—
—
0
0
21
294
0.71
0.81
20.3
11.5
—
—
—
0
0
263
2845
0.90
0.80
4.0
4.1
16.14
7.94
mg/mmol
0.97
172
1831
93
1079
0.85
0.80
1.3
1.3
43.19
42.20
iu/ml
0.03
29
334
557
5338
1.10
0.79
3.6
3.6
15.14
15.09
pmol/l
0.16
494
4706
11
66
1.67
0.79
1.2
1.1
—
65.60
—
0
5
761
7415
1.12
0.77
28.1
14.3
—
—
—
0
0
17
115
1.49
0.77
2.7
2.3
104.88
105.23
mmol/l
0.14
17
115
17
115
1.49
0.77
2.7
2.3
4.15
4.13
mmol/l
0.09
17
115
25
183
1.38
0.76
1.6
2.1
—
—
—
0
0
9
54
1.67
0.74
2.8
1.6
—
—
—
0
0
68
572
1.20
0.73
1.5
1.4
—
—
—
0
0
19
134
1.43
0.71
1.1
1.6
—
—
—
0
0
7
42
1.67
0.68
1.3
1.4
—
—
—
0
0
38
303
1.26
0.67
1.0
1.2
158.83
107.06
iu/ml
—
10
117
46
376
1.23
0.66
4.5
4.4
—
—
—
0
0
51
422
1.22
0.66
2.6
2.4
—
—
—
0
0
11
70
1.58
0.65
1.8
1.9
2.50
3.79
ug/l
0.59
11
65
10
62
1.62
0.65
1.2
1.2
—
—
—
0
0
7
44
1.60
0.65
1.1
1.1
—
—
—
0
0
176
1922
0.90
0.64
1.7
1.8
268613578.73
19313450.89
pmol/l
0.64
137
1543
5
29
1.73
0.64
1.0
1.1
—
18.43
—
0
7
12
79
1.53
0.62
1.3
1.3
—
—
nmol/l
—
0
0
8
49
1.64
0.62
1.6
1.4
1.12
0.93
g/l
—
8
49
5
30
1.67
0.61
1.2
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
10.2
—
0.67
—
0
20
0
20
0.00
0.60
0.0
1.1
—
232.25
—
0
12
11
160
0.68
0.56
1.5
1.5
—
—
—
0
0
159
1727
0.91
0.54
4.3
4.1
1.02
1.02
kg/l
0.56
18
265
63
547
1.16
0.51
1.6
1.5
—
—
—
0
0
17
224
0.75
0.50
1.4
1.5
—
—
—
0
0
7
49
1.43
0.46
3.1
1.5
—
—
—
0
0
12
86
1.40
0.44
2.8
1.8
—
—
—
0
0
15
113
1.33
0.43
1.3
1.1
—
—
—
0
0
16
122
1.32
0.42
1.0
1.1
—
—
—
0
0
676
6625
1.07
0.41
4.5
4.5
2.27
2.03
mu/l
2.65
609
5876
0
19
0.00
0.39
0.0
6.8
—
—
—
0
0
11
148
0.74
0.39
1.6
1.7
—
—
—
0
0
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
12
89
1.35
0.38
1.2
1.2
—
—
—
0
0
24
198
1.22
0.36
1.2
1.2
—
—
—
0
0
25
213
1.18
0.29
1.7
1.5
—
—
—
0
0
11
139
0.79
0.27
1.3
1.4
—
—
—
0
0
22
256
0.86
0.25
1.4
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
6.63
—
0
6
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
15.44
—
0
10
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
209
2018
1.05
0.21
4.3
4.1
0.00
0.01
estimate
0.50
85
578
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
5
43
1.16
0.21
1.2
1.0
—
1.11
—
0
19
134
1280
1.05
0.21
1.2
1.2
4.41
1.72
u/ml
0.31
15
341
261
2683
0.96
0.19
3.2
3.3
1219.54
168.01
mg/l
1.41
171
1723
10
122
0.82
0.19
1.0
1.3
—
—
—
0
0
21
236
0.89
0.17
8.6
4.6
—
—
—
0
0
5
69
0.72
0.17
1.0
1.8
11.66
10.61
%
—
5
69
14
121
1.16
0.15
1.1
1.9
3.04
4.51
iu/l
—
5
43
77
734
1.05
0.14
4.1
3.1
—
—
—
0
0
5
44
1.14
0.10
1.2
1.0
—
3.59
—
0
21
7
81
0.86
0.07
1.1
1.2
499.29
367.63
nmol/l
—
7
69
46
442
1.04
0.07
1.1
1.3
—
—
—
0
0
90
878
1.03
0.07
2.2
2.5
5.32
7.85
ug/l
0.94
72
766
9
100
0.90
0.06
3.4
4.3
371.11
343.78
umol/l
—
9
85
269
2719
0.99
0.06
3.2
3.2
7.27
7.50
mmol/l
0.41
225
2257
46
444
1.04
0.06
5.1
3.6
—
—
—
0
0
54
524
1.03
0.05
2.2
3.0
—
—
—
0
0
20
194
1.03
0.00
5.5
2.6
—
—
—
0
0
11
112
0.98
0.00
1.4
2.4
—
—
—
0
0
17
173
0.98
0.00
4.3
3.6
28.08
26.14
mg/l
0.08
11
116
13
129
1.01
0.00
1.6
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
4.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
21
210
1.00
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
6
64
0.94
0.00
1.0
1.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: HLP_C3_CLL – Chronic lymphocytic leukaemia, helper endpoint

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).