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This is a non-core endpoint: only basic statistics are computed.

Marginal zone B-cell lymphoma

C3_MARGINAL_ZONE_LYMPHOMA

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C83.80, C83.89
  • Cancer registry: Topography ICD-O-3 ANY
  • Cancer registry: Morphology ICD-O-3 9699
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

322

4. Check minimum number of events

None

322

5. Include endpoints

None

322

6. Filter based on genotype QC (FinnGen only)

314

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF8

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 314 158 156
Unadjusted period prevalence (%) 0.06 0.06 0.07
Median age at first event (years) 65.48 63.62 67.36

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
322
Matched controls
3220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
307.7
270
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
105.1
267.0
142
24
XW000
NOMESCO Finland
Bone marrow biopsy
67.5
217.7
125
30
JN4BD
NOMESCO Finland
Extensive body CT
32.6
182.4
133
68
A03FA01
ATC
metoclopramide; systemic, rectal
12.5
110.9
146
200
H02AB02
ATC
dexamethasone; systemic
48.7
105.5
63
16
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
+∞
88.7
81
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
24.9
88.6
66
33
WF002
NOMESCO Finland
Radical radiotherapy
287.2
87.1
85
*
JN4AD
NOMESCO Finland
Body CT examination
12.7
80.9
91
97
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
22.3
79.7
62
34
A04AA01
ATC
ondansetron; systemic, rectal
23.9
78.3
59
30
XX3DW
NOMESCO Finland
Time consuming IT work
12.4
67.8
75
77
JN6AD
NOMESCO Finland
CT of torso and neck
107.2
57.2
61
7
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
57.0
53
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
330.3
56.1
55
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
55.9
52
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
315.9
53.9
53
*
WZC00
NOMESCO Finland
Treatment plan or consultation
5.6
52.4
167
522
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
49.2
46
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
10.6
49.1
59
67
L03AA13
ATC
pegfilgrastim; parenteral
260.5
45.2
45
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
44.8
42
*
WW500
NOMESCO Finland
Blood transfusion
19.2
44.3
36
21
ZX120
NOMESCO Finland
Intravenous
8.2
44.2
66
98
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
477.4
43.2
42
*
9699/3-C77.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of lymph node, NOS
+∞
41.6
39
*
L03AA02
ATC
filgrastim; parenteral
451.2
41.1
40
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
39.4
37
*
C85.7
ICD-10 Finland
Other specified types of non-Hodgkin lymphoma
+∞
37.2
35
*
9699/3-C16.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of stomach, NOS
+∞
36.1
34
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
387.2
35.7
35
*
Z51.5
ICD-10 Finland
Palliative care
9.3
32.0
41
50
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
67.2
31.8
36
6
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
10.0
30.0
36
40
C83.89
ICD-10 Finland
Other types of diffuse non-Hodgkin's lymphoma
+∞
29.6
28
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
29.6
28
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
29.6
28
*
M04AA01
ATC
allopurinol; systemic
4.4
28.8
92
271
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.8
28.1
74
187
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
152.8
27.1
28
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.8
26.3
69
173
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.7
25.9
44
74
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
9.0
24.8
32
39
C83.8
ICD-10 Finland
Other non-follicular lymphoma
+∞
24.3
23
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
135.1
23.9
25
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.6
23.3
63
161
9699/3-C42.1
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of bone marrow
+∞
23.2
22
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
23.2
22
*
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
90.1
23.0
25
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
10.1
23.0
27
29
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
48.9
22.7
27
6
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
5.2
22.3
50
109
PJA10
NOMESCO Finland
Exploration of lymph nodes
67.5
22.2
25
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
22.1
21
*
130
Kela drug reimbursment
Malignant tumour
+∞
22.1
21
*
9699/3-C77.8
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of lymph nodes of multiple regions
+∞
22.1
21
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
22.1
21
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
123.4
21.9
23
*
HA1AA
NOMESCO Finland
X-ray mammography
8.7
21.2
28
35
1XC02, ,
NOMESCO Finland
64.6
21.2
24
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
21.1
20
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
21.1
20
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
21.1
20
*
9699/3-C34.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of lung, NOS
+∞
21.1
20
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
21.1
20
*
R50.9
ICD-10 Finland
Fever, unspecified
3.9
21.0
72
219
9699/3-C07.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of parotid gland
+∞
20.0
19
*
WX402
NOMESCO Finland
General anaesthesia
3.4
19.6
86
308
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
7.2
19.5
30
45
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
18.9
18
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
18.8
139
670
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
18.2
110
474
C82.9
ICD-10 Finland
Follicular lymphoma, unspecified
+∞
17.9
17
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
17.9
17
*
WZC30
NOMESCO Finland
Teaching
3.7
17.9
65
205
D70.82
ICD-10 Finland
Drug-induced neutropenia
100.7
17.8
19
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
190.0
17.7
18
*
H02AB06
ATC
prednisolone; systemic
2.7
17.2
194
1146
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
67.0
16.9
19
*
C83.39
ICD-10 Finland
Diffuse non-Hodgkin's large cell lymphoma UNS
+∞
16.8
16
*
PJA12
NOMESCO Finland
Sentinel node biopsy
178.9
16.7
17
*
GD1AD
NOMESCO Finland
Thorax CT examination
5.2
16.6
36
76
CFA20
NOMESCO Finland
Biopsy of conjunctiva
42.5
16.5
20
5
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.0
16.3
37
81
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
26.1
16.2
22
9
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
18.4
15.9
24
14
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
15.8
15
*
9699/3-C69.0
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of conjunctiva
+∞
15.8
15
*
9699/3-C69.6
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of orbit, NOS
+∞
15.8
15
*
ZX112
NOMESCO Finland
Subcutaneous
24.8
15.3
21
9
Z3231
NOMESCO Finland
Registered nurse
2.7
15.1
113
537
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
14.2
183
1116
C88.4
ICD-10 Finland
Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lyphoma]
+∞
13.6
13
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
13.6
13
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
10.0
13.2
26
28
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
10.0
13.2
26
28
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
12.7
31
72
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
72.8
12.7
14
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
12.6
12
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
12.6
12
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
12.6
12
*
H02AB07
ATC
prednisone; oral
3.0
12.6
66
258
CAA30
NOMESCO Finland
Biopsy of orbit
135.1
12.5
13
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.8
12.3
40
116
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
48.6
12.0
14
*
JN4CD
NOMESCO Finland
Very extensive body CT
11.7
11.7
21
19
A02BC02
ATC
pantoprazole; systemic
2.5
11.6
244
1781
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
11.5
11
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
11.5
11
*
C83.1
ICD-10 Finland
Mantle cell lymphoma
+∞
11.5
11
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
11.5
11
*
115
Kela drug reimbursment
Breast cancer
+∞
11.5
11
*
9699/3-C44.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of skin, NOS
+∞
11.5
11
*
9699/3-C08.0
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of submandibular gland
+∞
11.5
11
*
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
9.4
11.5
23
26
D70.89
ICD-10 Finland
Neutropenic splenomegaly
62.1
10.7
12
*
B01AB05
ATC
enoxaparin; parenteral
2.3
10.6
116
641
116
Kela drug reimbursment
Prostate cancer
+∞
10.5
10
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
10.5
10
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
10.5
10
*
CBA10
NOMESCO Finland
Biopsy of eyelid
24.3
10.3
14
6
N02AA05
ATC
oxycodone; systemic
2.7
10.2
64
273
Z2221
NOMESCO Finland
Medical doctor
2.3
10.1
99
519
P01BA02
ATC
hydroxychloroquine; oral
3.2
9.9
42
144
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
56.7
9.7
11
*
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
56.7
9.7
11
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
9.6
145
901
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
9.6
68
308
9699/3-C80.9
ICD-O-3
Marginal zone B-cell lymphoma, NOS, of unknown primary site
+∞
9.4
9
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
9.4
9
*
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
9.4
9
*
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
9.4
9
*
1AA09, ,
NOMESCO Finland
+∞
9.4
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
9.4
9
*
A04AD12
ATC
aprepitant; systemic
+∞
9.4
9
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
9.4
9
*
L01AA02
ATC
chlorambucil; oral
+∞
9.4
9
*
C83.01
ICD-10 Finland
Lymphoplasmacytic lymphoma
+∞
9.4
9
*
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
11.1
9.4
17
16
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.7
9.4
21
29
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.5
9.3
23
54
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
9.0
80
400
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.0
9.0
43
158
A07AA02
ATC
nystatin; oral
3.7
8.9
29
84
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
51.4
8.7
10
*
TGE00
NOMESCO Finland
Needle biopsy of mediastinum
51.4
8.7
10
*
J05AB11
ATC
valaciclovir; oral
2.5
8.7
60
268
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.4
8.6
17
19
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
10.5
8.6
16
16
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
8.6
125
760
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
20.7
8.5
12
6
Z85.7
ICD-10 Finland
Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
+∞
8.4
8
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
8.4
8
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
8.4
8
*
D48.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other specified sites
+∞
8.4
8
*
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
8.4
8
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
8.4
8
*
WX002
NOMESCO Finland
Sedation and analgesia
2.3
8.4
79
405
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.7
8.2
26
74
HAB40
NOMESCO Finland
Wedge excision of mammary gland
34.3
8.1
10
*
ZX108
NOMESCO Finland
Inhalation
22.7
8.1
11
5
R06AE07
ATC
cetirizine; oral
2.0
8.0
134
851
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
7.8
222
1684
D31.6
ICD-10 Finland
Benign neoplasm: Orbit, unspecified
46.1
7.7
9
*
ELB30
NOMESCO Finland
Excision of submandibular gland
18.9
7.7
11
6
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
18.9
7.7
11
6
ZXE00
NOMESCO Finland
One hour or less
2.0
7.6
127
802
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.1
7.6
32
109
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
25.7
7.6
10
*
D37.00
ICD-10 Finland
Aryepiglottic fold marginal zone
25.7
7.6
10
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.2
7.5
31
105
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
7.3
95
548
HAC20
NOMESCO Finland
Total mastectomy
+∞
7.3
7
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
7.3
7
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
7.3
7
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
YJ1BD
NOMESCO Finland
Extensive CT examination of abdomen for dose design of radiotherapy
+∞
7.3
7
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
7.3
7
*
JFB00
NOMESCO Finland
Partial resection of small intestine
16.2
7.3
11
7
UJF32
NOMESCO Finland
Coloscopy
2.0
7.3
94
542
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.9
7.2
21
56
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
7.2
129
833
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
17.1
6.8
10
6
ZXA05
NOMESCO Finland
Left side
2.0
6.7
94
555
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
23.1
6.7
9
*
ED1AA
NOMESCO Finland
Mandibular X-ray examination
23.1
6.7
9
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
6.7
43
185
JMA10
NOMESCO Finland
Transabdominal total splenectomy
71.2
6.4
7
*
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.0
6.4
92
548
TDM10
NOMESCO Finland
Puncture of maxillary antrum
4.0
6.3
18
47
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.9
6.3
30
110
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
18.5
6.3
9
5
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.4
6.3
23
72
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.1
6.3
26
88
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
6.3
6
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
+∞
6.3
6
*
L01BC06
ATC
capecitabine; oral
+∞
6.3
6
*
KAC11
NOMESCO Finland
Total nephrectomy with capsule, transcutaneous
+∞
6.3
6
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
6.3
6
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
6.3
6
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
6.3
6
*
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
6.3
6
*
ELB00
NOMESCO Finland
Excision or exploration of lesion of salivary gland
+∞
6.3
6
*
YJ1AD
NOMESCO Finland
CT examination of abdomen for dose design of radiotherapy
+∞
6.3
6
*
C82.00
ICD-10 Finland
Follicular nodular non-Hodgkin's lymphoma, ungraded
+∞
6.3
6
*
D11.70
ICD-10 Finland
Gland sublingual
27.3
6.3
8
*
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
27.3
6.3
8
*
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
27.3
6.3
8
*
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
5.5
6.2
17
32
B02.9
ICD-10 Finland
Zoster without complication
2.9
6.1
30
112
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
6.0
47
221

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
157
79
37.83
219.14
2.0
1.3
—
—
—
0
0
166
119
27.73
196.94
1.2
1.3
—
—
—
0
0
179
202
18.70
161.47
1.3
1.5
—
—
—
0
0
184
221
18.09
159.13
1.3
1.4
—
—
—
0
0
194
264
16.97
153.48
1.4
1.6
—
—
—
0
0
85
20
57.38
146.39
1.4
1.1
—
—
—
0
0
130
171
12.07
100.95
3.5
2.2
9.68
10.72
g/l
1.24
125
157
111
141
11.49
87.52
2.5
1.4
2.10
1.23
g/l
1.68
106
130
64
31
25.52
86.94
1.4
1.4
—
—
—
0
0
74
7
136.66
71.37
1.5
1.0
—
—
—
0
0
273
1127
10.35
66.79
11.8
5.3
—
—
—
0
0
107
178
8.51
66.46
1.8
1.3
—
—
—
0
0
263
1089
8.72
62.57
10.9
5.0
0.75
0.69
%
0.99
258
1009
277
1215
10.16
61.70
10.4
4.8
0.58
0.59
e9/l
0.35
258
1053
266
1123
8.87
61.65
11.1
5.0
2.83
3.01
%
0.46
261
1042
276
1221
9.82
60.40
10.4
4.8
0.04
0.04
e9/l
1.56
258
1061
265
1129
8.61
60.31
11.5
5.3
9.93
8.67
%
7.21
260
1048
278
1241
10.08
60.18
10.4
4.9
1.86
1.84
e9/l
0.05
264
1097
266
1149
8.56
59.23
11.3
5.2
27.28
27.51
%
0.11
261
1072
265
1144
8.44
58.93
10.4
5.0
57.20
57.47
%
0.13
257
1068
277
1262
9.55
57.63
10.9
5.0
0.18
0.20
e9/l
0.85
259
1114
285
1346
10.72
56.71
19.2
5.7
3.53
4.28
e9/l
8.95
273
1180
249
1097
6.60
51.38
6.9
3.2
35.35
35.68
g/l
0.44
240
1012
90
165
7.18
50.11
6.0
3.7
0.68
0.77
%
0.16
52
41
84
159
6.79
45.03
6.3
3.8
0.11
0.06
%
0.19
44
35
81
150
6.88
44.33
6.0
3.8
0.46
0.30
%
0.59
41
37
92
200
6.04
42.62
2.1
1.6
66.98
67.42
g/l
0.18
85
176
193
802
4.51
39.46
2.6
1.6
—
—
—
0
0
111
307
4.99
38.68
3.7
1.9
1.89
1.70
%
0.62
105
277
42
7
68.66
37.16
3.7
1.3
0.33
0.25
e9/l
—
42
7
245
1255
4.98
36.74
8.8
5.2
1.22
1.21
mmol/l
0.29
210
1083
94
236
5.21
36.61
3.7
1.9
73.90
66.92
e9/l
0.72
82
187
74
154
5.94
35.50
6.3
3.8
0.00
0.03
%
0.49
33
30
43
49
9.97
35.37
1.5
1.3
—
—
—
0
0
40
43
10.48
34.29
1.3
1.3
—
—
—
0
0
41
10
46.78
34.00
2.9
1.6
30.88
44.87
%
—
41
10
185
834
3.86
31.72
4.9
2.0
2.35
2.36
mmol/l
0.36
173
697
34
33
11.40
31.20
1.3
1.3
—
—
—
0
0
127
455
3.96
30.42
2.0
1.2
2.28
2.81
g/l
1.22
101
256
77
189
5.04
30.40
1.4
1.1
—
—
—
0
0
221
1151
3.93
29.83
7.2
4.9
1.22
1.21
mmol/l
0.41
216
1025
31
31
10.96
27.81
2.1
1.3
33.71
33.42
pg
0.11
31
31
162
728
3.47
26.75
5.3
3.1
7.40
7.40
ph
0.01
41
117
149
648
3.42
25.73
5.6
3.6
—
—
—
0
0
61
142
5.07
25.40
2.1
1.4
2.46
2.69
ug/l
0.32
45
109
132
540
3.45
25.04
13.6
4.3
—
—
—
0
0
202
1083
3.32
24.13
15.1
7.9
0.00
0.00
e9/l
0.48
184
894
128
575
3.04
19.93
5.5
3.2
87.33
87.57
%
0.04
118
560
24
6
43.08
19.79
1.5
1.0
—
—
—
0
0
25
31
8.66
19.02
2.6
1.3
—
—
—
0
0
190
1099
2.78
17.81
3.8
2.2
—
—
—
0
0
24
32
8.02
17.20
1.1
1.2
317.50
246.53
u/ml
0.42
16
17
140
708
2.73
16.90
3.8
2.0
—
—
—
0
0
20
6
35.39
15.93
4.4
1.5
15.81
30.23
u/l
—
20
6
115
545
2.73
15.55
3.3
1.9
—
—
—
0
0
204
1276
2.63
15.52
9.8
14.5
1.06
1.33
inr
9.66
61
361
26
47
5.93
14.07
1.2
1.2
—
—
—
0
0
23
39
6.27
13.25
1.0
1.0
—
—
—
0
0
78
329
2.81
12.94
2.4
2.2
24.47
23.33
%
0.18
68
280
85
379
2.69
12.64
1.9
1.2
—
—
—
0
0
54
192
3.18
12.09
2.0
1.9
0.20
0.21
g/l
0.38
48
169
79
350
2.67
11.83
2.3
2.1
2.21
2.29
g/l
0.61
73
321
83
390
2.52
10.94
2.6
2.1
13.39
13.32
umol/l
0.02
78
357
35
103
3.69
10.48
3.4
1.6
1.64
1.53
g/l
0.21
30
91
19
18
11.14
10.42
6.4
5.2
—
—
—
0
0
117
661
2.21
9.99
2.5
2.1
3.11
3.04
mg/l
0.11
108
553
21
30
7.41
9.18
1.7
2.6
—
—
—
0
0
79
393
2.34
9.03
2.5
1.7
29.88
29.37
s
0.28
74
380
58
254
2.57
8.73
3.7
2.0
4.91
6.62
umol/l
2.30
53
223
18
38
4.96
8.22
1.3
1.3
109.61
367.79
miu/ml
—
5
14
137
872
1.99
8.17
4.1
3.6
67.52
101.12
e6/l
0.47
96
605
157
1048
1.97
8.16
2.8
2.2
80.95
78.31
nmol/l
0.47
151
903
122
747
2.02
8.11
3.6
3.0
21.60
130.34
e6/l
0.66
94
563
20
33
6.39
7.98
1.1
1.0
—
—
—
0
0
47
195
2.65
7.86
6.7
6.5
—
—
—
0
0
112
678
2.00
7.60
3.8
2.9
0.27
0.44
e6/l
1.04
85
495
109
655
2.00
7.54
3.7
2.9
—
—
—
0
0
156
1059
1.92
7.53
3.5
2.6
262.54
124.01
ug/l
2.07
146
960
104
620
2.00
7.33
1.5
1.3
—
—
—
0
0
227
1756
1.99
7.28
5.2
4.2
—
—
—
0
0
15
20
7.81
6.98
2.1
2.2
—
—
—
0
0
15
20
7.81
6.98
1.1
1.1
—
—
—
0
0
75
404
2.12
6.91
2.8
2.9
2.39
2.54
e6/l
0.05
45
211
70
371
2.13
6.72
2.1
1.9
—
—
—
0
0
26
85
3.24
6.63
2.2
1.8
—
—
—
0
0
48
219
2.40
6.57
2.3
2.1
30.67
35.36
u/l
0.51
42
180
55
270
2.25
6.36
6.2
3.1
—
—
—
0
0
296
2592
2.76
6.16
31.1
12.3
20.30
23.81
mg/l
0.88
274
1991
24
79
3.20
6.06
1.3
1.2
2.66
2.22
u/ml
—
8
13
93
568
1.90
5.93
3.4
3.8
415.90
268.39
ng/l
0.19
74
461
84
498
1.93
5.85
3.1
2.7
508.79
532.86
mosm/kgh2o
0.58
77
411
31
122
2.71
5.73
5.3
8.4
—
—
—
0
0
12
16
7.74
5.68
1.2
1.0
—
—
—
0
0
44
208
2.29
5.55
5.8
5.5
1.20
1.41
mmol/l
0.80
44
203
89
551
1.85
5.39
1.7
1.7
1230.47
1164.13
nmol/l
0.27
70
417
83
505
1.87
5.30
3.1
2.3
4.66
5.41
e6/l
0.34
76
448
13
24
5.60
4.96
1.1
1.1
—
—
—
0
0
12
22
5.62
4.64
1.0
1.0
—
—
—
0
0
42
210
2.15
4.63
1.8
1.5
—
—
—
0
0
11
19
5.95
4.48
1.6
1.7
—
—
—
0
0
85
548
1.75
4.41
1.7
1.7
1.32
1.11
mg/l
0.38
68
430
15
38
4.09
4.36
6.6
2.7
55.93
57.08
%
0.09
15
38
15
38
4.09
4.36
5.3
2.2
2.96
4.58
e9/l
2.62
15
38
22
85
2.70
4.24
2.8
2.1
1.56
0.25
g/l
—
10
25
45
240
2.02
4.19
4.4
3.1
2.36
2.19
mmol/l
0.10
40
207
9
13
7.09
4.19
1.2
2.3
2.12
4.02
nmol/l
—
9
13
28
125
2.36
4.03
5.0
7.0
26.20
25.12
mmol/l
0.76
28
125
111
789
1.62
3.93
3.7
3.1
—
—
—
0
0
12
28
4.41
3.85
1.4
1.4
—
—
—
0
0
8
12
6.80
3.69
1.4
1.3
—
—
—
0
0
34
172
2.09
3.65
1.3
1.2
—
—
—
0
0
43
240
1.91
3.52
4.5
3.1
5.92
5.78
kpa
0.34
43
232
154
1211
1.52
3.38
2.3
2.0
92.54
95.48
pmol/l
0.33
92
603
7
10
7.13
3.38
1.0
1.0
—
—
—
0
0
7
10
7.13
3.38
1.0
1.0
—
—
—
0
0
7
10
7.13
3.38
1.0
1.0
—
—
—
0
0
224
1910
1.57
3.37
4.0
4.0
—
—
—
0
0
8
14
5.83
3.36
1.5
1.1
—
—
—
0
0
23
103
2.33
3.31
2.3
2.1
163.48
311.62
ug/l
1.03
23
96
10
24
4.27
3.22
1.1
1.2
—
—
—
0
0
7
11
6.48
3.20
1.3
1.5
25.78
11.27
ug/l
—
7
11
7
11
6.48
3.20
1.6
1.1
—
—
—
0
0
48
287
1.79
3.18
2.0
1.7
—
—
—
0
0
6
8
7.61
3.06
1.2
1.1
61.17
62.50
nmol/l
—
6
8
110
823
1.51
2.98
3.0
2.1
57.25
62.74
u/l
0.37
101
753
20
90
2.30
2.86
1.7
1.6
—
—
—
0
0
151
1222
1.44
2.69
3.5
3.6
0.00
0.00
estimate
-0.00
37
207
53
342
1.66
2.68
1.2
1.3
1224.44
533.01
titre
1.04
18
83
23
115
2.08
2.58
1.4
1.3
—
—
—
0
0
6
11
5.53
2.55
1.2
1.0
—
—
—
0
0
20
95
2.18
2.54
1.5
1.2
—
—
—
0
0
11
37
3.04
2.51
1.3
1.4
84.64
68.19
pmol/l
0.38
11
37
14
57
2.52
2.48
3.1
2.3
1.60
1.54
mg/l
0.13
14
51
299
2805
1.92
2.42
34.2
14.6
82.66
78.55
umol/l
1.04
299
2805
30
169
1.85
2.42
2.8
2.6
18.67
4.72
e9/l
0.65
24
122
43
270
1.68
2.42
1.3
1.2
—
—
—
0
0
233
2553
0.68
2.32
5.8
6.5
39.37
40.47
mmol/mol
1.15
213
2357
30
172
1.82
2.30
1.3
1.3
—
—
—
0
0
8
23
3.54
2.28
1.3
1.0
—
—
—
0
0
24
128
1.95
2.28
6.5
3.2
—
—
—
0
0
5
9
5.62
2.22
1.0
1.1
—
—
—
0
0
5
9
5.62
2.22
1.0
1.1
—
—
—
0
0
9
30
3.06
2.16
1.1
1.3
—
—
—
0
0
192
1661
1.39
2.15
3.5
2.9
48.41
48.64
u/l
0.02
180
1527
150
1247
1.38
2.15
3.7
3.6
0.00
0.00
estimate
-0.00
35
186
9
31
2.96
2.09
1.2
1.6
—
—
—
0
0
124
1003
1.38
2.08
3.3
3.4
4.80
5.84
ph
—
5
61
10
38
2.68
2.02
1.0
1.2
—
—
—
0
0
136
1122
1.37
2.01
3.2
3.8
22.95
38.50
ng/l
2.73
100
838
111
888
1.38
1.98
2.6
3.1
1874.27
1415.41
ng/l
0.46
99
752
8
27
3.01
1.95
1.5
1.7
275.00
270.59
mosm/kgh2o
—
8
17
5
11
4.60
1.95
1.6
1.5
9.80
9.73
mmol/l
—
5
11
6
16
3.80
1.94
2.0
1.0
—
—
—
0
0
92
715
1.40
1.94
1.7
1.5
20.71
20.84
nmol/l
0.02
83
598
18
92
2.01
1.94
1.5
1.2
—
1.26
—
0
8
69
514
1.44
1.84
1.3
1.3
6.16
2.05
u/ml
0.54
15
138
146
1231
1.34
1.83
5.0
4.9
0.00
0.00
estimate
-0.00
34
188
12
53
2.31
1.83
2.0
1.1
—
—
—
0
0
106
856
1.36
1.75
2.2
2.2
222.63
210.36
u/l
0.05
95
796
5
13
3.89
1.72
1.0
1.0
—
—
—
0
0
10
41
2.48
1.66
1.0
1.1
—
—
—
0
0
69
879
0.73
1.56
3.0
3.2
—
—
—
0
0
14
72
1.99
1.51
1.4
1.2
—
—
—
0
0
43
305
1.47
1.48
2.0
1.5
—
—
—
0
0
29
190
1.58
1.43
3.4
3.3
—
—
—
0
0
25
159
1.62
1.39
2.3
2.5
—
—
—
0
0
76
606
1.33
1.34
3.5
3.5
—
—
—
0
0
102
859
1.27
1.20
4.4
4.1
—
—
—
0
0
8
38
2.13
1.19
1.4
1.2
—
—
—
0
0
6
26
2.33
1.19
1.0
1.1
—
—
—
0
0
26
175
1.53
1.17
1.3
1.4
—
35.53
—
0
11
0
33
0.00
1.17
0.0
2.8
—
—
—
0
0
8
39
2.08
1.16
1.4
1.6
—
—
—
0
0
11
58
1.93
1.13
1.3
1.1
—
—
—
0
0
260
2726
0.76
1.11
4.9
5.5
2.55
2.68
mmol/l
1.42
233
2484
12
66
1.85
1.10
1.9
3.6
—
—
—
0
0
251
2643
0.77
1.10
4.3
4.8
1.40
1.48
mmol/l
1.84
226
2405
5
21
2.40
1.09
1.2
1.3
—
—
—
0
0
254
2666
0.78
1.03
4.2
4.9
4.44
4.58
mmol/l
1.32
228
2440
79
936
0.79
1.01
3.1
3.3
2504.80
193.11
mg/l
1.00
51
586
283
2715
1.35
0.97
24.0
12.0
—
—
—
0
0
214
1988
1.23
0.96
4.0
3.8
14.89
14.93
pmol/l
0.08
200
1783
85
990
0.81
0.92
3.6
3.9
8.90
6.99
mg/mmol
0.18
50
605
6
28
2.16
0.92
1.2
1.2
—
—
—
0
0
299
2898
1.44
0.92
43.9
18.3
38.83
40.24
%
4.14
285
2669
77
652
1.24
0.86
3.9
3.8
0.00
0.00
estimate
-0.00
35
187
6
31
1.95
0.85
1.2
1.2
—
—
—
0
0
6
31
1.95
0.85
1.2
1.2
—
—
—
0
0
26
190
1.40
0.82
5.1
4.7
—
—
—
0
0
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
6
33
1.83
0.79
1.2
1.2
—
—
—
0
0
10
59
1.72
0.76
2.0
2.0
123.20
133.20
g/l
—
5
40
10
59
1.72
0.76
2.2
2.5
—
—
—
0
0
5
24
2.10
0.75
1.2
1.2
—
—
—
0
0
84
958
0.83
0.72
3.0
3.2
7.36
7.49
mmol/l
0.10
66
783
20
143
1.42
0.72
1.2
1.1
183.31
94.79
iu/ml
—
7
58
54
451
1.24
0.69
1.3
1.3
34.41
40.95
iu/ml
0.21
20
146
7
42
1.68
0.69
3.1
2.5
4.20
4.08
mmol/l
—
7
42
7
42
1.68
0.69
3.1
2.5
107.29
105.02
mmol/l
—
7
42
7
42
1.68
0.69
3.1
2.5
—
—
—
0
0
64
740
0.83
0.64
1.7
1.7
1.31
1.35
mmol/l
0.10
55
613
8
50
1.62
0.61
1.3
3.5
—
—
—
0
0
73
638
1.19
0.60
3.4
3.3
—
—
—
0
0
8
55
1.47
0.56
1.3
1.6
—
—
—
0
0
8
123
0.64
0.56
1.4
1.5
—
—
—
0
0
11
159
0.68
0.55
1.5
1.4
—
—
—
0
0
7
108
0.64
0.49
15.9
9.1
—
—
—
0
0
7
46
1.53
0.48
2.7
2.8
—
—
—
0
0
7
46
1.53
0.48
3.3
2.2
—
—
—
0
0
70
622
1.16
0.48
1.5
1.7
541.12
8032561.98
pmol/l
0.50
58
498
50
433
1.18
0.47
1.2
1.3
6.11
17.52
u/ml
1.25
18
152
11
77
1.44
0.46
1.2
1.1
—
—
—
0
0
7
50
1.41
0.45
1.1
2.8
5.60
5.01
kpa
—
7
50
7
50
1.41
0.45
1.1
2.8
7.86
8.45
kpa
—
7
50
63
560
1.16
0.43
3.1
2.6
0.74
0.73
ug/l
0.04
41
376
14
105
1.35
0.42
1.4
1.5
—
—
—
0
0
23
281
0.80
0.41
1.5
1.5
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
183.98
—
0
17
8
61
1.32
0.40
2.0
1.6
—
—
—
0
0
5
36
1.39
0.38
1.2
1.4
—
—
—
0
0
6
42
1.44
0.35
1.5
2.0
—
—
—
0
0
31
265
1.19
0.35
2.2
2.2
148.00
118.21
ug/g
0.32
26
202
250
2561
0.89
0.33
3.9
4.3
1.36
1.28
mmol/l
0.68
223
2311
250
2445
1.10
0.27
5.0
4.7
1.95
2.49
mu/l
0.54
230
2200
272
2672
1.12
0.26
5.0
4.9
5.91
6.06
mmol/l
1.39
246
2415
17
142
1.21
0.25
1.1
1.4
—
—
—
0
0
5
41
1.22
0.22
1.2
1.3
—
—
—
0
0
25
220
1.15
0.22
1.4
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
5.9
—
24.65
—
0
10
0
10
0.00
0.21
0.0
5.4
—
—
—
0
0
8
101
0.79
0.21
1.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
171.45
—
0
13
0
13
0.00
0.21
0.0
1.1
—
132.46
—
0
13
6
48
1.25
0.20
1.0
1.9
—
—
—
0
0
12
99
1.22
0.20
1.2
2.0
—
—
—
0
0
5
44
1.14
0.10
1.2
1.4
0.60
0.56
nmol/l
—
5
37
104
1015
1.04
0.08
4.8
4.0
2.51
1.94
ug/l
1.09
94
904
7
68
1.03
0.08
2.0
2.6
—
—
—
0
0
56
573
0.97
0.04
4.2
3.9
1.02
1.02
kg/l
0.01
11
86
14
149
0.94
0.03
3.1
3.5
—
—
—
0
0
12
117
1.03
0.00
4.3
4.9
—
—
—
0
0
19
185
1.03
0.00
1.8
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
10.4
—
0.70
—
0
8
0
5
0.00
-0.00
0.0
2.2
—
1.18
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
23
230
1.00
-0.00
5.0
2.9
—
—
—
0
0
8
81
0.99
-0.00
4.4
4.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
11.7
—
1171.71
—
0
7
0
7
0.00
-0.00
0.0
5.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
14.1
—
2071.71
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_MARGINAL_ZONE_LYMPHOMA – Marginal zone B-cell lymphoma

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).