Discitis, unspecified

M13_DISCITIS

discitis: Inflammation of an intervertebral disc or disk space which may lead to disk erosion. Until recently, discitis has been defined as a nonbacterial inflammation and has been attributed to aseptic processes (e.g., chemical reaction to an injected substance). However, recent studies provide evidence that infection may be the initial cause, but perhaps not the promoter, of most cases of discitis. Discitis has been diagnosed in patients following discography, myelography, lumbar puncture, paravertebral injection, and obstetrical epidural anesthesia. Discitis following chemonucleolysis (especially with chymopapain) is attributed to chemical reaction by some and to introduction of microorganisms by others.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M46.4
  • Cause of death: ICD-10 M46.4

2 out of 7 registries used, show all original rules.

618

4. Check minimum number of events

None

618

5. Include endpoints

None

618

6. Filter based on genotype QC (FinnGen only)

605

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M46
Name in latin
Discitis non specificata

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3832 1518 2294
Only index persons 3640 1453 2187
Unadjusted period prevalence (%)
Whole population 0.06 0.04 0.06
Only index persons 0.07 0.05 0.08
Median age at first event (years)
Whole population 64.99 67.41 63.41
Only index persons 64.70 66.94 63.21

-FinnGen-

Key figures

All Female Male
Number of individuals 605 237 368
Unadjusted period prevalence (%) 0.14 0.08 0.17
Median age at first event (years) 66.86 65.47 67.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
618
Matched controls
6180
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
190.3
307.7
167
12
M46.4
ICD-10 Finland
Discitis, unspecified
4503599627370496.0
307.7
617
*
M48.0
ICD-10 Finland
Spinal stenosis
63.6
265.6
150
31
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
27.5
264.9
198
104
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
36.0
198.3
129
45
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
33.3
194.8
130
49
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
47.4
193.8
116
30
M46.3
ICD-10 Finland
Infection of intervertebral disc (pyogenic)
+∞
153.7
141
*
M54.5
ICD-10 Finland
Low back pain
7.8
146.7
337
826
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.3
135.9
237
432
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
8.8
123.4
188
292
N03AX16
ATC
[U] pregabalin
7.0
114.5
236
503
M54.9
ICD-10 Finland
Dorsalgia, unspecified
11.2
113.0
133
148
M54.4
ICD-10 Finland
Lumbago with sciatica
8.6
106.8
159
238
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
59.2
104.5
59
11
N02AA05
ATC
oxycodone; systemic
6.0
99.4
250
633
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
25.3
97.5
70
31
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
28.3
95.9
66
26
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
269.6
92.3
92
*
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
28.1
88.6
61
24
N03AX12
ATC
[U] gabapentin; oral
7.0
88.0
161
298
N02AX02
ATC
tramadol; systemic, rectal
5.1
87.7
388
1534
J01FF01
ATC
clindamycin; systemic
5.0
87.4
313
1048
L03
ICPC
Low back symptom/complaint
5.2
83.0
240
672
A41.9
ICD-10 Finland
Sepsis, unspecified
10.6
81.7
96
105
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
7.2
77.9
132
224
J04AB02
ATC
rifampicin; systemic
27.5
76.6
53
21
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
18.7
74.8
61
36
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.1
71.4
122
208
R50.9
ICD-10 Finland
Fever, unspecified
5.1
70.5
193
509
J01MA12
ATC
levofloxacin; systemic
4.4
64.2
229
736
A40.8
ICD-10 Finland
Other streptococcal sepsis
21.2
64.0
49
25
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
125.0
63.2
67
6
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.2
61.6
227
744
A41.8
ICD-10 Finland
Other specified sepsis
14.9
61.2
56
41
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.2
60.7
149
355
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
27.4
59.3
41
16
ZXD05
NOMESCO Finland
Urgent procedure
3.8
57.2
297
1222
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
56.6
209
681
J01CF05
ATC
flucloxacillin; systemic
7.0
56.2
93
152
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
108.5
54.9
59
6
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.2
53.3
68
82
C03CA01
ATC
furosemide; systemic
3.5
51.9
310
1376
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.6
51.1
409
2169
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.3
50.2
157
449
N02AJ06
ATC
codeine and paracetamol; systemic
3.4
49.9
318
1460
SPAT1255
SPAT
Intravenous administration of medicine
5.6
48.5
103
214
TPH04
NOMESCO Finland
Cathetrisation of vein
3.6
46.0
214
801
A46
ICD-10 Finland
Erysipelas
3.9
45.9
168
536
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.1
45.5
150
444
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.2
44.7
333
1648
L28
ICPC
Limited function/disability (L)
3.8
44.7
178
600
JN3AD
NOMESCO Finland
Abdominal CT examination
4.4
44.5
131
356
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.9
43.6
63
88
G06.1
ICD-10 Finland
Intraspinal abscess and granuloma
+∞
43.2
41
*
N02BF01
ATC
gabapentin; oral
6.8
43.1
72
118
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
41.1
39
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.5
39.9
69
117
S97
ICPC
Chronic ulcer skin
5.2
39.9
89
192
A02BC02
ATC
pantoprazole; systemic
3.5
38.5
484
3130
N06AX21
ATC
duloxetine; oral
4.8
37.7
93
218
M03BC01
ATC
orphenadrine (citrate); systemic
3.5
37.3
160
560
M54.8
ICD-10 Finland
Other dorsalgia
10.6
36.6
41
41
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
9.8
36.0
43
47
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.0
35.8
118
345
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
62.6
35.6
41
7
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.2
35.2
106
290
B01AB05
ATC
enoxaparin; parenteral
2.9
35.1
269
1309
N02BF02
ATC
pregabalin; oral
7.2
34.9
54
81
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
34.4
236
1080
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
127.2
34.1
36
*
M46.2
ICD-10 Finland
Osteomyelitis of vertebra
+∞
33.6
32
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.4
33.5
145
508
WX408
NOMESCO Finland
General anesthesy, balanced
2.9
33.3
217
964
H02AB06
ATC
prednisolone; systemic
2.7
33.1
350
1992
X59
ICD-10 Finland
Exposure to unspecified factor
3.3
33.1
158
587
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.8
32.6
235
1099
JN4AD
NOMESCO Finland
Body CT examination
3.6
32.5
123
394
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
340.3
32.2
32
*
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
56.1
31.6
37
7
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
31.5
30
*
N02BE01
ATC
paracetamol; systemic, rectal
7.5
31.4
591
4596
J01DB01
ATC
cefalexin; oral
4.2
31.4
550
4057
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
10.5
31.2
35
35
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.8
30.8
59
110
L86
ICPC
Back syndrome with radiating pain
6.3
30.5
53
90
J01MA02
ATC
ciprofloxacin; systemic
2.6
30.3
307
1690
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.3
29.6
135
485
M54.2
ICD-10 Finland
Cervicalgia
5.5
29.6
60
118
I50.9
ICD-10 Finland
Heart failure, unspecified
3.1
29.5
151
581
SPAT1254
SPAT
Administration of medicine
3.2
29.3
136
494
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
4.3
29.0
82
213
A01
ICPC
Pain general/multiple sites
4.4
28.6
78
197
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
10.8
28.2
31
30
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
30.2
27.9
37
13
S18
ICPC
Laceration/cut
2.5
27.7
334
1969
AA1AD
NOMESCO Finland
CT of head and brain
2.6
27.7
231
1146
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
27.6
254
1320
M04AA01
ATC
allopurinol; systemic
3.0
27.4
145
567
UJF32
NOMESCO Finland
Coloscopy
2.7
27.2
210
1001
M47.9
ICD-10 Finland
Spondylosis, unspecified
65.1
27.2
31
5
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.0
27.2
142
551
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
11.2
27.1
29
27
NF1AA
NOMESCO Finland
Hip X-ray examination
3.9
27.0
88
253
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
26.6
178
789
M13.9
ICD-10 Finland
Arthritis, unspecified
4.3
26.4
73
186
A28
ICPC
Limited function/disability NOS
2.9
26.4
161
679
R4110
NOMESCO Finland
Physiotherapy
2.6
26.2
217
1067
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
28.4
26.0
35
13
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.8
25.9
62
141
TQW11
NOMESCO Finland
Vacuum treatment of wound
8.2
25.8
35
45
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
25.5
284
1598
TKC20
NOMESCO Finland
Catheterisation of bladder
3.9
25.1
80
226
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
8.8
25.1
32
38
M54
ICD-10 Finland
Dorsalgia
3.8
25.1
85
251
M47.82
ICD-10 Finland
Other spondylosis, cervical region
24.6
25.1
35
15
M03BX02
ATC
tizanidine; oral
2.4
25.0
370
2355
M54.3
ICD-10 Finland
Sciatica
7.6
24.8
36
50
ZXE10
NOMESCO Finland
More than one and less than three hours
2.4
24.7
270
1501
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.6
24.5
61
143
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.1
24.5
72
192
JN4BD
NOMESCO Finland
Extensive body CT
3.1
24.4
119
442
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
24.0
113
411
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.5
23.9
91
290
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
249.3
23.8
24
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.3
23.8
103
356
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
8.5
23.7
31
38
N06AA09
ATC
amitriptyline; systemic
4.0
23.7
71
192
M79.6
ICD-10 Finland
Pain in limb
2.4
23.5
260
1446
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
23.1
22
*
NA1AD
NOMESCO Finland
Cervical spine CT examination
5.4
22.7
46
90
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.8
22.7
75
217
J01CF02
ATC
cloxacillin; systemic
7.1
22.3
34
50
ZXD35
NOMESCO Finland
Usual procedure
6.0
22.2
40
70
M46.5
ICD-10 Finland
Other infective spondylopathies
+∞
22.0
21
*
M54.6
ICD-10 Finland
Pain in thoracic spine
5.4
22.0
45
89
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
22.0
133
554
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.4
21.9
201
1024
A06AD11
ATC
lactulose; oral
2.8
21.8
129
531
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.2
21.8
98
346
B01AA03
ATC
warfarin; systemic
2.5
21.7
178
860
L70
ICPC
Infection of musculoskeletal system
45.1
21.6
26
6
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.8
21.4
70
201
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
21.1
201
1039
M43.1
ICD-10 Finland
Spondylolisthesis
22.4
21.0
30
14
NA1DG
NOMESCO Finland
Cervical spine very extensive MRI examination with high intensity magnet
+∞
21.0
20
*
NAS20
NOMESCO Finland
Incision and debridement of infection of vertebra, unspecified
+∞
21.0
20
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.6
20.9
73
219
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.4
20.8
42
82
A07EC01
ATC
sulfasalazine; oral, rectal
3.9
20.8
64
176
R60.0
ICD-10 Finland
Localized oedema
3.1
20.7
100
367
WX110
NOMESCO Finland
Infiltration anesthesia
2.4
20.6
441
3172
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.7
20.5
69
202
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
5.8
20.3
38
69
N06AX11
ATC
mirtazapine; oral
2.3
20.3
218
1183
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.5
20.2
52
125
M10.9
ICD-10 Finland
Gout, unspecified
3.4
20.1
78
251
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
19.9
19
*
SPAT1229
SPAT
Assessment of need for aid
3.6
19.6
70
213
TK800
NOMESCO Finland
Hemodialysis
6.0
19.5
35
61
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
27.1
19.3
26
10
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.6
19.2
69
211
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.0
18.8
56
150
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
72.2
18.8
21
*
L04AA13
ATC
[U] leflunomide
7.3
18.8
28
40
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
7.6
18.8
27
37
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.8
18.8
110
448
L17
ICPC
Foot/toe symptom/complaint
2.3
18.7
188
987
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.7
18.5
111
457
C07AB07
ATC
bisoprolol; oral
2.1
18.5
353
2380
J01XX08
ATC
linezolid; systemic
31.1
18.5
24
8
P19
ICPC
Drug abuse
45.5
18.3
22
5
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.2
18.3
51
130
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.7
18.2
108
442
WX892
NOMESCO Finland
Monitored bed care
3.2
18.0
76
257
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
27.7
17.9
24
9
Z3231
NOMESCO Finland
Registered nurse
2.2
17.6
195
1060
Z3226
NOMESCO Finland
Physiotherapist
2.5
17.6
131
599
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
5.8
17.6
33
60
I10
ICD-10 Finland
Essential (primary) hypertension
2.2
17.4
427
3136
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
16.5
17.2
27
17
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.3
17.1
156
781
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.1
17.0
218
1254
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.5
17.0
131
609
R06.0
ICD-10 Finland
Dyspnoea
2.2
16.8
191
1047
SPAT1211
SPAT
Application of soft bandage
3.1
16.8
74
257
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.9
16.7
51
139
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
16.7
16
*
NA3CM
NOMESCO Finland
Lumbar spine extensive MRI examination with 3 Tesla magnet
+∞
16.7
16
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
16.7
16
*
N05BA04
ATC
oxazepam; oral
2.2
16.7
172
905
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.2
16.7
191
1049
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
5.3
16.6
34
67
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
7.5
16.6
24
33
B18.2
ICD-10 Finland
Chronic viral hepatitis C
13.9
16.6
28
21
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
3.2
16.6
71
242
L88
ICPC
Rheumatoid/seropositive arthritis
5.2
16.4
34
68
J01MA14
ATC
moxifloxacin; systemic
3.0
16.3
79
289
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
16.3
150
752
N05CF01
ATC
zopiclone; oral
2.1
16.3
214
1238
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.7
16.3
55
161
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.5
16.2
32
61
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.3
16.2
24
34
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.3
16.2
161
834
M25.5
ICD-10 Finland
Pain in joint
2.2
16.2
180
976
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
16.2
201
1138
R60.9
ICD-10 Finland
Oedema, unspecified
3.9
16.0
49
134
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.9
16.0
29
51
N06AX16
ATC
venlafaxine; oral
2.9
16.0
84
322
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
15.0
16.0
26
18
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.4
16.0
32
62
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
15.9
66
221
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
15.7
15
*
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
15.7
15
*
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
+∞
15.7
15
*
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
15.7
15
*
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.5
15.7
39
91
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.3
15.7
64
212
ZX120
NOMESCO Finland
Intravenous
2.9
15.5
80
303
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
15.3
112
506
M54.1
ICD-10 Finland
Radiculopathy
13.5
15.3
26
20
I50.0
ICD-10 Finland
Congestive heart failure
3.0
15.3
74
271
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.9
15.2
76
283
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.0
15.1
33
69
ZXE00
NOMESCO Finland
One hour or less
2.0
15.0
257
1627
A03
ICPC
Fever
2.6
15.0
98
420
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
14.9
230
1403
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
14.8
139
700
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
14.8
313
2127
M01AH01
ATC
celecoxib; oral
2.4
14.8
112
514
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
25.8
14.8
20
8
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.9
14.8
44
118
C03DA01
ATC
spironolactone; oral
2.5
14.7
106
475
SAA03
NOMESCO Finland
Extended examination of mouth
2.0
14.7
229
1400
NA3DM
NOMESCO Finland
Lumbar spine very extensive MRI examination with 3 Tesla magnet
+∞
14.6
14
*
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
+∞
14.6
14
*
M03BC51
ATC
orphenadrine, combinations; systemic
2.2
14.6
158
843
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.2
14.4
30
60
ZXA05
NOMESCO Finland
Left side
2.1
14.4
172
953
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.3
14.4
38
93
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.9
14.4
32
68
D07AC01
ATC
betamethasone; topical
2.0
14.4
233
1443
SPAT1263
SPAT
Sampling
2.0
14.2
260
1677
C08CA01
ATC
amlodipine; oral
1.9
14.2
271
1773
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.1
14.2
64
225
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
14.0
90
382
205
Kela drug reimbursment
Chronic hypertension
2.0
13.9
206
1232
M45
ICD-10 Finland
Ankylosing spondylitis
54.6
13.9
16
*
N05AH04
ATC
quetiapine; oral
2.4
13.8
103
468
E66.8
ICD-10 Finland
Other obesity
4.2
13.8
38
96
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.1
13.8
61
212
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.3
13.8
28
55
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.6
13.6
26
48
WX872
NOMESCO Finland
Intensive care
3.2
13.6
56
186
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
5.4
13.5
27
52
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
26.4
13.4
18
7
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
10.8
13.3
25
24
M01AH05
ATC
etoricoxib; oral
1.9
13.3
344
2466
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.5
13.2
89
386
A29
ICPC
General symptom/complaint other
2.4
13.1
98
446
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.8
13.1
41
114
K02.1
ICD-10 Finland
Caries of dentine
1.9
13.1
330
2344
P01BA02
ATC
hydroxychloroquine; oral
3.1
13.0
56
191
R33
ICD-10 Finland
Retention of urine
2.7
13.0
77
313
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.7
13.0
30
66
SPAT1216
SPAT
Assessment of functional ability
2.3
12.9
115
564
SPAT1301
SPAT
No procedures
2.0
12.9
202
1227
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
51.1
12.9
15
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
51.1
12.9
15
*
UKC02
NOMESCO Finland
Cystoscopy
2.2
12.8
128
658
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.9
12.8
23
40
WX002
NOMESCO Finland
Sedation and analgesia
2.1
12.6
145
787
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.2
12.6
52
173
R06AE07
ATC
cetirizine; oral
1.9
12.6
236
1520
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
+∞
12.5
12
*
M46.0
ICD-10 Finland
Spinal enthesopathy
+∞
12.5
12
*
ZXA00
NOMESCO Finland
Right side
2.0
12.5
182
1076
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.3
12.5
49
158
WW200
NOMESCO Finland
Immunization
5.0
12.5
27
56
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
132.6
12.5
13
*
N06AB04
ATC
citalopram; systemic
2.2
12.4
126
653
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.3
12.3
25
28
NHQ40
NOMESCO Finland
Amputation of toe
6.0
12.3
22
38
J01CA04
ATC
amoxicillin; systemic
2.0
12.3
480
3891
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.5
12.3
82
353
SPAT1262
SPAT
Handing over of treatment supplies
2.1
12.3
133
705
L03.0
ICD-10 Finland
Cellulitis of finger and toe
3.0
12.3
58
209
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.3
12.2
48
155
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
12.2
65
250
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.3
12.2
47
150
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.4
12.1
44
135
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.1
12.1
54
188
M01AB05
ATC
diclofenac; systemic, rectal
1.8
12.0
379
2854
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
12.0
42
126
R5110, ,
SPAT
3.1
12.0
51
173
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
11.9
97
457
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.3
11.9
47
152
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
11.9
243
1602
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.3
11.9
45
142
S29
ICPC
Skin symptom/complaint other
2.1
11.8
126
663
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
11.8
116
591
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
10.8
11.8
22
21
R53
ICD-10 Finland
Malaise and fatigue
2.0
11.8
145
806
TQW80
NOMESCO Finland
Local dermatologic skincare
4.9
11.8
26
55
E0000UV, ,
ATC
1.8
11.7
246
1633
R1250
NOMESCO Finland
Evaluation of functional capability
5.7
11.7
22
40
A02BC05
ATC
esomeprazole; systemic
1.8
11.7
238
1566
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
66.2
11.6
13
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.9
11.6
190
1164
R06.2
ICD-10 Finland
Wheezing
3.8
11.6
35
95
127
Kela drug reimbursment
Transplant complication
5.8
11.5
21
37
M53.1
ICD-10 Finland
Cervicobrachial syndrome
3.2
11.5
46
150
E000001, ,
ATC
2.1
11.5
123
648
B01AF02
ATC
apixaban; oral
2.2
11.5
104
513
Z72.2
ICD-10 Finland
Drug use
122.2
11.5
12
*
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
10.8
11.3
21
20
L84
ICPC
Back syndrome without radiat pain
4.0
11.3
33
87
N05BA01
ATC
diazepam; systemic, rectal
2.4
11.3
86
393
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
11.3
126
675
XF600
NOMESCO Finland
Bloodpressure measurement
3.1
11.3
48
163
C09AA02
ATC
enalapril; systemic
2.0
11.2
149
849
WX213
NOMESCO Finland
Lower leg blockade
25.6
11.2
15
6
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
20.5
11.2
16
8
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
3.5
11.1
38
112
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.8
11.1
309
2221
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.9
11.1
163
961
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
11.1
75
325
M01AB55
ATC
diclofenac, combinations; oral
3.1
11.1
47
159
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
5.9
11.1
20
35
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
11.0
40
123
SPAT1252
SPAT
Overall medication plan or its review
2.8
11.0
58
222
Z01.2
ICD-10 Finland
Dental examination
1.8
11.0
240
1606
WX204
NOMESCO Finland
Axillary plexus blockaced
4.3
10.9
28
67
207
Kela drug reimbursment
Chronic arrhythmias
2.0
10.9
129
705
E66.9
ICD-10 Finland
Obesity, unspecified
4.4
10.9
27
63
N05CF02
ATC
zolpidem; oral
2.2
10.8
104
525
G47.3
ICD-10 Finland
Sleep apnoea
2.0
10.8
143
814
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
18.2
10.8
16
9
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
5.7
10.8
20
36
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
10.7
66
273
SPAT1260
SPAT
Consultation of another employee
2.1
10.7
116
614
NA2DG
NOMESCO Finland
Thoracal spine very extensive MRI examination with high intensity magnet
61.1
10.7
12
*
R02
ICPC
Shortness of breath/dyspnoea
2.3
10.6
89
424
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.0
10.6
49
174
WX402
NOMESCO Finland
General anaesthesia
2.0
10.6
127
696
L04AX03
ATC
methotrexate; systemic
2.7
10.6
61
244
S06.0
ICD-10 Finland
Concussion
2.5
10.6
71
306
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.9
10.6
50
180
M70.6
ICD-10 Finland
Trochanteric bursitis
2.5
10.6
69
294
B01AB10
ATC
tinzaparin; parenteral
2.4
10.5
75
333
L02
ICPC
Back symptom/complaint
2.8
10.5
54
204
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.4
10.5
79
360
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.3
10.5
27
65
M53.2
ICD-10 Finland
Spinal instabilities
111.8
10.4
11
*
9211
FHL
Exploration or removal of diskusprolapse
+∞
10.4
10
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.1
10.4
29
74
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
33.1
10.4
13
*
Z76.0
ICD-10 Finland
Issue of repeat prescription
2.0
10.3
133
748
Z49.0
ICD-10 Finland
Preparatory care for dialysis
10.9
10.3
19
18
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
7.7
10.3
23
31
I50
ICD-10 Finland
Heart failure
3.8
10.3
31
84
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
4.2
10.3
27
66
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.0
10.2
29
75
L29
ICPC
Musculoskeletal sympt/complt other
2.7
10.2
55
213
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
8.1
10.2
22
28
L04AA06
ATC
mycophenolic acid; systemic
5.4
10.2
20
38
N06AB10
ATC
escitalopram; oral
2.1
10.2
102
523
X58
ICD-10 Finland
Exposure to other specified factors
2.3
10.2
84
398
SPAT1234
SPAT
Support of social functional capacity
3.1
10.2
42
140
W19
ICD-10 Finland
Unspecified fall
2.5
10.2
64
268
WX290
NOMESCO Finland
Other blockage of nerve
1.8
10.2
243
1661
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
4.1
10.1
28
71
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
10.1
56
220
EBA00
NOMESCO Finland
Extraction of tooth
1.8
10.1
207
1353
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.9
10.0
164
999
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.8
10.0
50
186
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.0
10.0
131
741
J01AA02
ATC
doxycycline; systemic
1.8
10.0
460
3779
N30.0
ICD-10 Finland
Acute cystitis
2.2
9.9
89
437
L13
ICPC
Hip symptom/complaint
2.1
9.9
108
572
N18.8
ICD-10 Finland
Other chronic renal failure
4.1
9.9
27
68
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.8
9.8
22
47
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
9.8
116
632
XA402
NOMESCO Finland
ENMG
9.8
9.8
19
20
B03XA02
ATC
darbepoetin alfa; parenteral
4.2
9.8
26
64
N30.9
ICD-10 Finland
Cystitis, unspecified
3.3
9.8
38
122
Z71.8
ICD-10 Finland
Other specified counselling
1.8
9.7
173
1080
K78
ICPC
Atrial fibrillation/flutter
2.4
9.7
69
306
I50.1
ICD-10 Finland
Left ventricular failure
2.8
9.6
48
178
J01CE08
ATC
benzathine benzylpenicillin; parenteral
11.6
9.6
17
15
SPAT1231
SPAT
Assessment of adjustments needed in living environment
4.9
9.6
21
44
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.3
9.6
81
387
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.2
9.6
39
129
WX704
NOMESCO Finland
Intubation
2.8
9.5
49
185
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
9.5
99
514
R03AC02
ATC
salbutamol; inhalant
1.7
9.5
299
2195
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
9.5
114
625
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.0
9.5
118
655
NAW10
NOMESCO Finland
Reoperation for superficial infection in in surgery of spine or neck
101.5
9.4
10
*
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
101.5
9.4
10
*
M48.9
ICD-10 Finland
Spondylopathy, unspecified
101.5
9.4
10
*
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
8.2
9.4
20
25
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
+∞
9.4
9
*
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
9.4
9
*
M60.0
ICD-10 Finland
Infective myositis
+∞
9.4
9
*
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
+∞
9.4
9
*
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
+∞
9.4
9
*
A40.1
ICD-10 Finland
Sepsis due to streptococcus, group B
22.1
9.4
13
6
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.8
9.4
48
181
A02BC03
ATC
lansoprazole; oral
1.8
9.3
169
1059
N19
ICD-10 Finland
Unspecified kidney failure
3.3
9.3
36
115
Z2446
NOMESCO Finland
Social worker
2.7
9.3
50
193
A02BC01
ATC
omeprazole; systemic
1.8
9.3
162
1003
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.5
9.3
59
248
SPAT1240
SPAT
Therapeutic discussion
2.6
9.3
57
236
P03
ICPC
Feeling depressed
3.0
9.3
42
148
QDA10
NOMESCO Finland
Incision of skin of lower limb
13.9
9.2
15
11
S76
ICPC
Skin infection other
2.9
9.2
43
154
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
4.4
9.2
23
54
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
9.2
57
237
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
8.5
9.1
19
23
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.7
9.1
21
46
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
9.1
112
619
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
37.3
9.0
11
*
L01BA01
ATC
methotrexate; systemic
4.3
9.0
23
55
M05BA04
ATC
alendronic acid; oral
2.5
9.0
58
246
T14.5
ICD-10 Finland
Injury of blood vessel(s) of unspecified body region
18.9
9.0
13
7
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
24.4
8.9
12
5
V03AE02
ATC
sevelamer; oral
24.4
8.9
12
5
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
24.4
8.9
12
5
TK810
NOMESCO Finland
Hemofiltration
12.8
8.9
15
12
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.9
8.9
43
157
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.3
8.9
73
345
A10AB05
ATC
insulin aspart; parenteral
2.5
8.8
59
254
K07
ICPC
Swollen ankles/oedema
3.0
8.8
39
136
SFA10
NOMESCO Finland
One-surface restoration
1.7
8.7
294
2180
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
8.7
213
1451
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
50.7
8.7
10
*
P01AB01
ATC
metronidazole; oral, rectal
1.7
8.7
217
1487
H02AB04
ATC
methylprednisolone; systemic
2.1
8.7
87
445
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.1
8.7
24
61
R5599
NOMESCO Finland
Other rehabilitation service
4.5
8.7
21
48
C09BA02
ATC
enalapril and diuretics; systemic
2.4
8.6
62
276
B01AB04
ATC
dalteparin; parenteral
3.1
8.6
36
121
Z50.1
ICD-10 Finland
Other physical therapy
3.0
8.6
38
132
ZZH40
NOMESCO Finland
Substitute of bone
16.6
8.6
13
8
NA2AD
NOMESCO Finland
Thoracic spine CT examination
16.6
8.6
13
8
C01AA05
ATC
digoxin; systemic
2.3
8.6
69
323
A04
ICPC
Weakness/tiredness general
2.1
8.6
84
426
L01
ICPC
Neck symptom/complaint
2.2
8.5
75
364
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.0
8.5
37
127
R04.0
ICD-10 Finland
Epistaxis
2.4
8.5
61
271
R52.9
ICD-10 Finland
Pain, unspecified
2.5
8.5
57
246
R05
ICD-10 Finland
Cough
1.9
8.5
123
717
Z02.7
ICD-10 Finland
Issue of medical certificate
2.7
8.5
45
173
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.9
8.5
41
150
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.8
8.4
25
67
M35.3
ICD-10 Finland
Polymyalgia rheumatica
3.2
8.4
34
112
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
2.7
8.4
45
174
M10.0
ICD-10 Finland
Idiopathic gout
3.0
8.4
36
123
M46.8
ICD-10 Finland
Other specified inflammatory spondylopathies
+∞
8.3
8
*
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
8.7
8.3
17
20
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.2
8.3
22
54
R81
ICPC
Pneumonia
3.4
8.3
29
87
M02AA07
ATC
piroxicam; topical
1.7
8.2
204
1391
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
8.2
384
3078
L14
ICPC
Leg/thigh symptom/complaint
2.5
8.2
53
225
S11
ICPC
Skin infection post-traumatic
8.3
8.1
17
21
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
17.5
8.1
12
7
L99
ICPC
Musculoskeletal disease other
6.4
8.1
20
32
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
8.1
222
1555
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
10.2
8.1
15
15
M01AB01
ATC
indometacin; systemic, rectal
2.4
8.1
57
252
WX882
NOMESCO Finland
High dependency care
3.6
8.1
26
74
N03AF02
ATC
oxcarbazepine; oral
3.9
8.0
23
60
D07AD01
ATC
clobetasol; topical
2.0
8.0
94
509
ZZA00
NOMESCO Finland
Split skin graft
3.4
8.0
28
84
L15
ICPC
Knee symptom/complaint
1.8
8.0
131
792
WX202
NOMESCO Finland
Supraclavicular plexus blockade
7.4
8.0
18
25
N03AE01
ATC
clonazepam; systemic
2.9
8.0
37
132
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
8.0
160
1028
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.8
8.0
24
65
SFA30
NOMESCO Finland
Three-surface restoration
1.6
8.0
237
1693
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
4.0
7.9
22
56
R42
ICD-10 Finland
Dizziness and giddiness
1.8
7.9
135
827
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
3.9
7.9
23
61
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.1
7.9
21
52
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
7.9
59
268
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
8.6
7.8
16
19
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
9.6
7.8
15
16
R52.0
ICD-10 Finland
Acute pain
3.7
7.8
24
66
WZC30
NOMESCO Finland
Teaching
1.9
7.8
101
566
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
7.8
38
140
XX1CT
NOMESCO Finland
Other puncture with CT guidance
45.6
7.7
9
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.1
7.7
77
393
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.3
7.6
29
92
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.1
7.6
32
108
H02AB07
ATC
prednisone; oral
2.0
7.6
84
445
M50.3
ICD-10 Finland
Other cervical disc degeneration
12.0
7.6
13
11
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.5
7.6
26
77
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.8
7.5
23
63
A12AA04
ATC
calcium carbonate; oral
4.3
7.5
19
45
M01AB51
ATC
indometacin, combinations; oral, rectal
4.3
7.5
19
45
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
81.0
7.4
8
*
QCA10
NOMESCO Finland
Incision of skin of upper limb
81.0
7.4
8
*
TAB20
NOMESCO Finland
Epidural puncture
81.0
7.4
8
*
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
81.0
7.4
8
*
SPAT1272
SPAT
Drug screening
81.0
7.4
8
*
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.8
7.4
22
59
S22.4
ICD-10 Finland
Multiple fractures of ribs
4.1
7.4
20
50
M01AC06
ATC
meloxicam; systemic, rectal
1.7
7.4
198
1372
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.6
7.3
44
180
A11CC03
ATC
alfacalcidol; systemic
3.6
7.3
24
69
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.6
7.3
41
162
N05BA12
ATC
alprazolam; oral
2.2
7.3
60
283
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.2
7.3
65
317
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
7.3
7
*
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
+∞
7.3
7
*
NA3BD
NOMESCO Finland
Extensive lumbar spine and sacrum CT examination
+∞
7.3
7
*
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
7.3
7
*
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
2.9
7.3
34
122
C09CA01
ATC
losartan; oral
1.7
7.3
166
1102
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.5
7.3
45
187
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.3
7.3
57
264
Y94.0
ICD-10 Finland
Accident at home
4.4
7.3
18
42
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
16.0
7.2
11
7
SFA20
NOMESCO Finland
Two-surface restoration
1.6
7.2
308
2385
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.3
7.2
26
80
A41.2
ICD-10 Finland
Sepsis due to unspecified staphylococcus
30.4
7.2
9
*
M43.0
ICD-10 Finland
Spondylolysis
20.3
7.1
10
5
X57
ICD-10 Finland
Unspecified privation
3.8
7.1
21
56
R51.80
ICD-10 Finland
Headache
2.1
7.1
73
376
KMAK, ,
NOMESCO Finland
1.6
7.1
262
1957
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.8
7.1
36
135
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
6.1
7.1
18
30
196
Kela drug reimbursment
Paricalcitol and cinacalcet
12.2
7.1
12
10
J01CF01
ATC
dicloxacillin; systemic
10.2
7.1
13
13
G54.0
ICD-10 Finland
Brachial plexus disorders
10.2
7.1
13
13
R52.2
ICD-10 Finland
Other chronic pain
4.3
7.1
18
43
I48.1
ICD-10 Finland
Persistent atrial fibrillation
2.8
7.0
34
125
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
7.0
28
92
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
5.9
7.0
18
31
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
7.0
215
1539
SPAT1153
SPAT
Removal of sutures
1.6
6.9
186
1285
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.0
6.9
30
103
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.2
6.9
27
87
SPAT1275
SPAT
Drug rehabilitation and replacement therapy of opioid-dependent person
14.0
6.9
11
8
ZXA10
NOMESCO Finland
Bilateral
1.8
6.9
118
721
K99
ICPC
Cardiovascular disease other
3.5
6.9
23
67
SPAT1265
SPAT
Breathalyser
8.4
6.9
14
17
SPAT1172
SPAT
Guidance concerning hydration
4.2
6.9
18
44
M05BB03
ATC
alendronic acid and colecalciferol; oral
4.2
6.9
18
44
E87.6
ICD-10 Finland
Hypokalaemia
3.1
6.9
28
93
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
6.9
339
2702
S91.1
ICD-10 Finland
Open wound of toe(s) without damage to nail
6.8
6.8
16
24
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
6.8
509
4478
A08
ICPC
Swelling
2.7
6.8
37
144
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
11.1
6.8
12
11
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.2
6.8
27
88
U14
ICPC
Kidney symptom/complaint
4.3
6.8
17
40
K08.3
ICD-10 Finland
Retained dental root
2.3
6.8
49
219
S61.9
ICD-10 Finland
Open wound of wrist and hand, part unspecified
3.6
6.8
22
63
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
40.5
6.8
8
*
E66.01
ICD-10 Finland
Obesity due to excess calories
2.4
6.7
45
194
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
22.8
6.7
9
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.5
6.7
16
25
Y96.9
ICD-10 Finland
Unspecified type of accident
5.6
6.7
18
33
Z49.2
ICD-10 Finland
Other dialysis
7.9
6.6
14
18
L04AB04
ATC
adalimumab; parenteral
7.9
6.6
14
18
XKD00
NOMESCO Finland
Uroflowmetry
1.8
6.6
119
737
N03AX09
ATC
lamotrigine; oral
3.4
6.6
23
69
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.4
6.6
23
69
R23.3
ICD-10 Finland
Spontaneous ecchymoses
4.2
6.6
17
41
SPAT1281
SPAT
Other administrative function
2.3
6.6
51
235
E66.00
ICD-10 Finland
Metabolic syndrome
2.6
6.6
39
159
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.8
6.5
32
118
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.1
6.5
26
85
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
3.7
6.5
20
55
J02AC01
ATC
fluconazole; systemic
1.6
6.5
173
1190
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.8
6.5
33
124
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.9
6.5
30
107
M70.2
ICD-10 Finland
Olecranon bursitis
3.0
6.5
28
96
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.8
6.5
31
113
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
6.4
64
326
T91.3
ICD-10 Finland
Sequelae of injury of spinal cord
70.6
6.4
7
*
J01FA06
ATC
roxithromycin; oral
1.6
6.4
218
1589
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.1
6.4
26
86
TQW40
NOMESCO Finland
Remowal of suture of skin
2.3
6.4
46
205
M02AA10
ATC
ketoprofen; topical
1.9
6.4
84
472
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.0
6.4
66
341
N05AH03
ATC
olanzapine; systemic
2.6
6.4
36
143
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.9
6.4
78
428
D02AE01
ATC
carbamide; topical
2.4
6.4
42
180
GD1AD
NOMESCO Finland
Thorax CT examination
2.4
6.4
42
180
N18.0
ICD-10 Finland
End-stage renal disease
6.7
6.4
15
23
L04AD01
ATC
ciclosporin; systemic
5.3
6.4
18
35
R10.0
ICD-10 Finland
Acute abdomen
3.7
6.4
20
56
SPAT1310
SPAT
Counselling related to known health issue
1.6
6.4
171
1179
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
8.3
6.4
13
16
L16
ICPC
Ankle symptom/complaint
2.1
6.4
58
286
P01
ICPC
Feeling anxious/nervous/tense
2.5
6.3
40
168
P16
ICPC
Acute alcohol abuse
5.6
6.3
17
31
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.5
6.3
21
61
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.3
6.3
23
71
D07BC01
ATC
betamethasone and antiseptics; topical
1.9
6.3
77
422
L04AB01
ATC
etanercept; parenteral
9.4
6.3
12
13
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
18.2
6.3
9
5
ACC51
NOMESCO Finland
Release of median nerve
2.5
6.3
40
169
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.6
6.3
210
1525
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
6.3
6
*
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
6.3
6
*
IFC01, ,
SPAT
+∞
6.3
6
*
71700, ,
ICD-8 Finland
+∞
6.3
6
*
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.0
6.3
72
387
D07AA02
ATC
hydrocortisone; topical
1.9
6.3
78
431
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
7.1
6.2
14
20
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
27.0
6.2
8
*
S91.3
ICD-10 Finland
Open wound of other parts of foot
3.7
6.2
19
52
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.2
6.2
50
234
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.2
6.2
24
77
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
3.2
6.2
24
77
62699
ICD-8 Finland
Disorders of menstruation, Other
3.6
6.2
20
57
P15
ICPC
Chronic alcohol abuse
3.5
6.2
21
62
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
7.8
6.1
13
17
R20.2
ICD-10 Finland
Paraesthesia of skin
2.7
6.1
33
128
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
6.1
46
209
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.8
6.1
18
48
L08
ICPC
Shoulder symptom/complaint
1.7
6.1
115
721
K92.1
ICD-10 Finland
Melaena
2.4
6.1
40
171
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
12.7
6.1
10
8
K55.2
ICD-10 Finland
Angiodysplasia of colon
12.7
6.1
10
8
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
6.1
156
1062
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
3.0
6.1
26
89
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
6.1
184
1304
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
6.8
6.1
14
21
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.6
6.1
33
129
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.5
6.1
20
58
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
10.2
6.0
11
11
N02AJ13
ATC
tramadol and paracetamol; systemic
5.3
6.0
17
33
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
6.0
55
271
Z94.0
ICD-10 Finland
Kidney transplant status
6.1
6.0
15
25
M01AH02
ATC
rofecoxib; oral
2.0
6.0
68
363

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
443
1413
8.54
147.47
10.8
4.2
—
—
—
0
0
291
681
7.19
130.36
3.0
2.0
—
—
—
0
0
473
2294
5.53
79.56
12.5
5.6
0.04
0.04
e9/l
1.11
433
1976
471
2287
5.45
78.80
12.4
5.6
0.66
0.60
e9/l
5.30
431
1959
474
2340
5.40
76.87
12.6
5.6
1.68
1.91
e9/l
2.45
436
2055
78
69
12.79
76.52
7.2
5.3
12.29
11.20
mg/l
0.87
73
61
474
2367
5.30
74.96
12.8
5.8
0.22
0.19
e9/l
1.81
436
2056
448
2144
4.96
74.91
12.3
6.2
—
—
—
0
0
122
208
7.06
71.42
2.6
2.0
4.21
2.47
ug/l
0.24
116
187
446
2180
4.76
71.06
13.0
5.7
3.04
2.86
%
0.77
437
2041
447
2191
4.76
70.88
13.5
6.0
8.96
8.97
%
0.02
437
2051
48
18
28.83
70.59
1.2
1.0
281.69
282.03
iu/ml
0.00
48
18
434
2112
4.54
68.70
12.7
5.8
0.65
0.65
%
0.01
425
1972
445
2232
4.55
66.84
13.1
5.9
23.53
26.68
%
7.18
435
2093
438
2195
4.42
65.28
12.9
5.7
60.96
58.09
%
5.13
427
2067
490
2690
4.97
63.68
16.8
9.3
4.65
4.13
e9/l
4.51
449
2336
463
2516
4.35
59.00
9.7
6.7
10.91
12.35
umol/l
2.43
454
2390
208
664
4.21
58.14
10.1
6.3
1.11
1.03
mmol/l
2.84
200
615
450
2414
4.18
58.02
13.9
7.1
1.20
1.21
mmol/l
2.05
404
2029
451
2432
4.16
57.48
26.7
16.7
1.43
1.34
inr
0.85
135
713
137
330
5.05
54.73
2.7
2.3
—
—
—
0
0
201
654
4.07
54.28
4.0
2.5
18.25
22.36
%
4.09
186
563
206
692
3.97
53.01
4.1
2.5
2.11
2.27
g/l
2.97
194
644
150
401
4.62
52.57
2.8
2.7
65.21
66.09
g/l
0.67
144
373
215
756
3.83
51.58
4.1
2.5
9.95
12.64
umol/l
6.18
205
702
163
477
4.28
50.60
13.9
7.6
13.28
10.45
mmol/l
3.99
156
450
407
2203
3.48
48.06
12.4
6.2
1.20
1.21
mmol/l
2.40
395
1997
395
2104
3.43
47.81
7.8
4.8
31.58
35.18
g/l
20.08
378
1961
86
156
6.24
46.66
3.0
3.4
35.45
52.18
mg/l
0.42
67
129
86
156
6.24
46.66
3.0
3.4
54.05
107.53
mg/l
0.71
67
126
278
1224
3.31
45.87
2.9
2.1
3.37
3.09
mg/l
1.00
247
1026
214
808
3.52
45.26
4.6
3.6
0.80
0.82
mmol/l
1.38
204
766
84
154
6.16
45.04
3.0
3.4
1.70
1.21
ratio
—
7
11
172
571
3.79
44.15
2.1
1.7
—
—
—
0
0
490
3095
3.82
42.74
7.1
4.0
1176.33
3106.74
e6/l
—
7
53
296
1406
3.12
42.05
4.9
2.9
—
—
—
0
0
521
3445
4.26
41.92
8.7
3.7
26.22
13.22
mm/h
23.70
506
3114
544
3725
4.84
41.19
17.2
7.5
93.35
79.18
u/l
9.46
529
3477
148
466
3.86
40.77
6.9
3.7
5.79
5.83
kpa
0.19
142
449
147
465
3.84
40.18
7.0
3.7
1.51
2.08
mmol/l
0.93
127
375
284
1351
3.04
39.71
4.3
3.1
0.66
0.48
e6/l
0.51
234
1032
332
1721
3.01
39.70
5.2
3.5
107.37
168.36
e6/l
0.56
262
1239
160
541
3.64
39.56
2.8
1.6
—
—
—
0
0
304
1504
3.01
39.55
4.5
3.1
43.26
126.19
e6/l
1.14
250
1167
293
1428
3.00
39.06
3.2
2.5
50.50
65.39
u/l
3.00
285
1318
272
1274
3.03
38.95
4.3
2.8
4872.64
6953.21
umol/l
0.31
237
1114
289
1406
2.98
38.52
2.8
2.1
365.55
296.94
u/l
0.16
275
1312
459
2904
3.26
37.30
9.6
4.8
6.91
6.83
mmol/l
0.37
450
2735
163
582
3.45
36.78
3.0
2.6
1.84
1.75
%
0.64
152
520
132
416
3.76
36.00
12.3
9.5
—
—
—
0
0
268
1299
2.88
35.27
4.3
3.0
—
—
—
0
0
284
1426
2.83
34.86
8.6
4.1
7.40
7.40
ph
0.21
56
288
340
1876
2.81
34.72
4.3
2.6
187.25
150.82
ug/l
1.90
322
1704
65
119
5.99
34.69
2.8
3.7
—
—
—
0
0
247
1156
2.89
34.59
13.5
6.8
—
—
—
0
0
299
1547
2.81
34.56
5.2
3.2
2734.70
1628.45
ng/l
2.09
274
1347
483
3225
3.28
34.15
7.2
4.0
—
—
—
0
0
95
245
4.40
34.09
1.5
2.0
1.78
1.58
g/l
0.93
87
213
372
2174
2.79
33.55
3.5
2.5
—
—
—
0
0
131
438
3.53
32.45
3.2
2.7
69.48
68.10
e9/l
0.17
92
335
51
79
6.95
32.01
1.5
1.5
—
—
—
0
0
289
1518
2.70
31.74
3.4
2.4
—
—
—
0
0
149
556
3.21
30.80
1.6
1.4
—
—
—
0
0
144
527
3.26
30.74
1.4
1.3
317.78
388.57
titre
0.49
36
105
358
2113
2.65
30.66
22.5
9.6
0.00
0.00
e9/l
0.45
303
1723
59
111
5.77
30.54
1.3
1.8
—
—
—
0
0
151
571
3.18
30.49
10.5
8.1
5.30
5.11
kpa
1.22
142
556
151
571
3.18
30.49
10.5
8.1
11.64
12.08
kpa
0.56
142
555
243
1193
2.71
30.24
1.7
1.5
18.61
21.19
nmol/l
1.50
225
990
220
1027
2.77
30.23
3.5
2.5
5.37
5.37
e6/l
0.00
203
932
141
519
3.22
29.73
10.9
8.6
95.92
95.32
%
0.81
135
506
150
575
3.12
29.51
10.6
8.1
1.34
1.33
mmol/l
0.01
126
467
317
1798
2.57
28.99
5.0
3.1
5.50
5.90
ph
—
8
115
280
1514
2.55
28.11
4.7
3.3
35.73
33.92
u/l
0.36
270
1440
55
105
5.65
27.99
1.7
1.5
52385.53
27010.81
e6/l
0.44
36
74
114
388
3.38
27.17
6.6
2.8
5.09
4.49
kpa
1.63
108
375
230
1149
2.60
27.06
3.1
2.4
—
—
—
0
0
180
799
2.77
26.82
3.6
2.7
1.58
1.09
e6/l
0.70
111
460
362
2242
2.48
26.60
5.8
3.4
0.00
0.00
estimate
-0.00
84
459
313
1818
2.46
26.47
3.0
2.2
75.37
77.48
nmol/l
0.61
290
1600
194
917
2.63
25.31
3.1
1.6
1.33
1.45
mg/l
0.35
165
724
68
170
4.37
25.19
3.4
2.0
11.40
10.51
g/l
0.54
63
151
315
1875
2.39
24.69
6.4
3.6
45.72
65.09
ng/l
0.53
263
1397
358
2254
2.40
24.66
5.8
3.3
0.00
0.01
estimate
0.50
78
413
355
2240
2.37
24.15
7.7
4.6
0.00
0.00
estimate
-0.00
81
435
197
959
2.55
24.00
2.3
1.8
1266.16
1134.85
nmol/l
0.87
161
724
171
779
2.65
23.87
3.8
2.9
3.30
1.81
e6/l
1.08
102
440
585
4763
5.27
23.37
49.4
14.2
36.80
27.64
mg/l
7.81
560
3774
104
367
3.20
23.18
3.0
2.9
11.17
10.64
g/l
0.38
96
339
202
1013
2.48
22.93
4.1
2.8
501.42
558.26
mosm/kgh2o
3.99
182
872
129
519
2.88
22.81
3.1
2.9
10.89
9.33
umol/l
0.28
115
462
326
2029
2.28
22.29
2.4
2.0
95.39
94.46
pmol/l
0.14
194
1056
99
350
3.18
21.94
5.2
4.0
134.49
89.47
ng/l
2.43
90
302
59
147
4.33
21.90
2.9
1.9
32.97
37.31
g/l
4.73
54
129
95
328
3.24
21.90
5.1
3.6
7.39
7.41
ph
0.56
15
40
115
448
2.93
21.49
2.0
1.6
—
—
—
0
0
37
63
6.18
21.12
1.7
1.3
—
—
—
0
0
118
471
2.86
21.06
2.3
2.1
0.18
0.21
g/l
2.07
108
441
48
105
4.87
20.91
5.5
3.9
—
—
—
0
0
110
429
2.90
20.46
2.4
2.2
28.24
138.97
u/l
0.52
91
379
137
602
2.64
20.24
1.3
1.2
8.90
18.64
u/ml
0.92
46
220
27
34
8.26
20.16
10.9
3.1
—
—
—
0
0
49
113
4.62
20.02
2.5
3.3
32.25
35.00
umol/l
0.50
44
105
140
635
2.56
19.31
1.5
1.2
53.98
43.75
iu/ml
0.23
57
204
94
349
3.00
19.04
4.6
4.1
0.64
0.51
%
0.40
44
125
109
439
2.80
19.02
3.0
2.2
8.57
7.57
ug/l
0.21
94
384
44
98
4.76
18.74
3.3
2.7
14.55
16.03
%
1.08
26
53
99
386
2.86
18.32
4.6
4.4
0.80
0.97
%
0.40
49
143
87
320
3.00
17.87
7.6
4.4
—
—
—
0
0
31
53
6.11
17.60
1.1
1.1
—
—
—
0
0
30
50
6.26
17.46
1.5
1.5
75.78
65.36
%
0.73
23
36
94
367
2.84
17.31
4.5
4.5
0.07
0.13
%
0.53
43
125
115
499
2.60
17.24
2.1
1.6
—
—
—
0
0
85
321
2.91
16.62
6.5
3.0
117.33
126.98
g/l
3.32
85
311
32
60
5.57
16.53
9.6
3.3
—
—
—
0
0
92
364
2.79
16.50
2.1
2.2
372.97
381.58
nmol/l
0.12
87
334
74
266
3.02
15.78
14.3
11.2
—
—
—
0
0
176
957
2.17
15.65
4.8
3.6
1026.80
358.34
ng/l
0.99
151
791
87
344
2.78
15.59
4.3
4.5
0.06
0.93
%
0.53
36
105
42
108
4.10
14.91
8.4
3.8
2.59
2.41
mmol/l
0.17
33
71
178
998
2.10
14.46
5.5
3.3
—
—
—
0
0
42
111
3.99
14.37
4.0
2.5
—
—
—
0
0
47
135
3.69
14.31
9.5
3.6
7.41
7.42
ph
0.48
41
115
34
77
4.61
14.18
1.6
1.5
—
—
—
0
0
34
78
4.55
13.96
6.4
3.7
—
—
—
0
0
585
5100
3.75
13.92
51.2
17.2
4.02
4.00
mmol/l
0.81
578
4938
45
128
3.71
13.89
3.4
3.2
2.32
1.73
mg/l
2.46
38
118
584
5088
3.69
13.87
50.8
17.0
138.87
139.66
mmol/l
10.80
577
4933
32
71
4.70
13.68
1.3
1.5
34.16
29.34
g/l
0.96
24
63
55
184
3.18
13.22
3.7
3.2
0.56
0.22
g/l
1.02
36
78
253
1652
1.90
13.03
4.2
3.5
2.33
2.35
mmol/l
1.17
225
1449
30
66
4.73
12.96
10.4
2.1
—
—
—
0
0
36
93
4.05
12.71
3.5
3.0
—
—
—
0
0
248
1637
1.86
12.14
5.1
3.2
7.00
7.58
mmol/l
1.05
217
1356
18
10
18.50
12.11
3.7
1.1
—
—
—
0
0
73
300
2.63
12.06
1.7
1.5
—
—
—
0
0
22
39
5.81
12.02
1.5
1.3
14627.69
108504.74
e6/l
0.52
13
23
33
85
4.04
11.70
3.7
2.7
4.67
4.52
e9/l
0.17
33
85
58
217
2.85
11.47
1.3
1.2
—
—
—
0
0
434
3440
1.88
11.37
4.1
3.6
14.80
14.97
pmol/l
0.66
398
3065
38
111
3.58
11.29
1.4
1.2
—
—
—
0
0
52
185
2.98
11.25
12.1
3.9
—
—
—
0
0
31
79
4.08
11.15
11.4
2.0
—
—
—
0
0
499
4155
2.04
11.12
46.8
17.2
16.04
15.27
%
1.91
493
4073
395
3057
1.81
11.01
5.4
2.9
78.49
53.63
u/l
4.45
378
2801
583
5191
3.17
10.96
23.6
10.2
27.09
26.24
u/l
0.45
569
4967
24
51
4.86
10.79
1.5
2.4
—
—
—
0
0
569
5012
2.71
10.76
38.1
13.7
—
—
—
0
0
33
91
3.77
10.66
4.7
3.0
61.64
57.40
%
1.16
33
91
32
87
3.82
10.54
11.1
2.0
—
—
—
0
0
32
88
3.78
10.38
11.0
2.0
—
—
—
0
0
26
62
4.33
10.19
2.0
2.4
1.52
1.31
g/24h
0.17
14
30
177
1100
1.85
10.17
2.0
1.8
457.82
40363236.62
pmol/l
1.46
146
882
24
54
4.58
10.10
1.5
1.3
—
—
—
0
0
23
50
4.74
10.08
1.5
1.4
—
—
—
0
0
135
771
1.96
10.01
1.9
1.5
3.40
2.52
g/l
2.91
96
470
232
1579
1.75
9.75
4.1
3.3
687.65
210.34
mg/l
0.80
176
1027
40
133
3.15
9.72
3.1
3.2
0.78
0.84
nmol/l
0.33
35
106
31
88
3.66
9.62
12.1
1.5
—
—
—
0
0
31
88
3.66
9.62
11.6
2.0
—
—
—
0
0
242
1680
1.72
9.40
4.6
3.9
24.75
7.93
mg/mmol
2.97
173
1086
110
599
2.02
9.30
1.2
1.2
—
—
—
0
0
189
1227
1.78
9.28
7.2
3.5
0.00
0.01
estimate
0.69
68
410
26
67
4.01
9.22
1.1
1.0
—
—
—
0
0
29
81
3.71
9.21
1.4
1.2
303.11
310.91
u/ml
0.04
19
45
592
5393
3.32
9.15
61.3
20.9
7.38
6.73
e9/l
9.10
585
5189
592
5394
3.32
9.13
61.3
20.9
4.15
4.49
e12/l
38.07
586
5190
58
244
2.52
9.12
6.3
3.7
—
—
—
0
0
591
5389
3.21
8.91
61.9
21.1
37.54
40.21
%
21.42
559
4996
26
69
3.89
8.87
1.1
1.0
—
—
—
0
0
591
5391
3.20
8.87
61.5
20.9
253.56
240.56
e9/l
3.98
583
5213
26
71
3.78
8.53
2.3
2.6
—
—
—
0
0
24
62
3.99
8.49
1.5
1.3
50855.64
1306.02
e6/l
0.50
14
44
27
76
3.67
8.49
3.0
2.3
—
—
—
0
0
86
442
2.10
8.47
5.1
3.0
317.51
231.71
ng/l
0.75
78
406
33
108
3.17
8.25
2.3
2.4
116.74
128.88
g/l
1.36
27
82
503
4338
1.86
8.22
5.1
4.3
2.39
2.01
mu/l
0.41
473
3863
427
3530
1.68
7.95
5.5
3.8
—
—
—
0
0
29
90
3.33
7.89
3.8
2.1
57.78
62.65
%
0.44
29
90
27
80
3.48
7.88
1.3
1.2
—
—
—
0
0
21
52
4.15
7.86
1.4
1.3
48.31
51.59
mmol/l
0.13
16
44
21
52
4.15
7.86
1.5
1.3
45275.09
29020.43
e6/l
0.20
11
28
44
175
2.63
7.76
2.2
1.9
—
—
—
0
0
151
971
1.73
7.45
6.4
3.5
1.02
1.02
kg/l
0.43
17
138
24
70
3.53
7.18
1.9
1.2
—
—
—
0
0
183
1254
1.65
7.08
5.7
3.1
—
—
—
0
0
519
4613
1.78
6.46
7.3
6.0
41.57
40.44
mmol/mol
1.51
491
4216
14
19
7.51
6.44
1.2
1.2
2.86
2.00
%
—
7
7
22
66
3.42
6.33
2.0
2.4
30.23
32.92
pg
1.44
22
66
36
144
2.59
6.31
4.5
3.6
—
—
—
0
0
140
920
1.67
6.28
4.1
3.2
2.48
2.45
mmol/l
1.46
119
820
72
388
1.97
6.21
6.2
3.0
—
—
—
0
0
127
818
1.70
6.13
1.3
1.2
3.57
1.21
u/ml
0.50
31
205
55
272
2.12
5.98
6.1
3.0
7.58
4.22
e9/l
0.51
47
213
32
124
2.67
5.97
1.3
1.1
—
—
—
0
0
20
60
3.41
5.76
1.4
1.6
—
—
—
0
0
19
56
3.47
5.62
2.6
3.8
—
—
—
0
0
26
94
2.84
5.53
1.4
1.7
—
—
—
0
0
55
281
2.05
5.51
3.5
2.5
0.66
0.26
e6/l
1.14
55
274
19
57
3.41
5.48
4.3
4.8
6.26
7.24
mmol/l
1.10
14
51
243
1872
1.49
5.33
2.2
2.2
—
—
—
0
0
15
30
5.10
5.28
1.3
2.3
—
—
—
0
0
14
26
5.48
5.25
1.1
1.7
—
—
—
0
0
11
15
7.44
5.16
1.9
3.8
—
—
—
0
0
54
281
2.01
5.15
1.1
1.2
—
—
—
0
0
27
104
2.67
5.12
1.1
1.0
—
—
—
0
0
24
87
2.83
5.09
2.5
2.7
—
—
—
0
0
24
88
2.80
4.99
1.2
1.8
—
—
—
0
0
13
24
5.51
4.93
1.5
1.1
—
—
—
0
0
528
4808
1.67
4.88
5.4
4.7
6.16
6.05
mmol/l
1.00
488
4300
17
52
3.33
4.78
1.1
1.1
—
—
—
0
0
17
53
3.27
4.64
4.3
3.7
—
—
—
0
0
72
427
1.78
4.63
2.4
2.3
163.30
151.51
ug/g
0.09
63
339
81
504
1.70
4.40
8.4
4.5
—
—
—
0
0
89
573
1.65
4.25
3.5
4.5
17.59
28.87
ug/l
0.30
76
467
38
187
2.10
4.23
1.5
1.6
—
—
—
0
0
10
17
5.96
4.14
2.0
1.4
—
—
—
0
0
45
240
1.94
4.04
5.1
3.7
—
—
—
0
0
20
75
2.72
4.02
1.9
2.6
—
—
—
0
0
8
11
7.35
3.87
1.8
8.9
43.81
42.68
%
—
8
11
9
15
6.07
3.82
1.3
2.7
—
—
—
0
0
9
15
6.07
3.82
1.0
1.0
—
—
—
0
0
18
66
2.78
3.78
1.3
1.8
0.84
0.93
g/l
0.10
13
49
15
50
3.05
3.71
1.1
1.2
—
—
—
0
0
15
50
3.05
3.71
2.1
2.5
—
—
—
0
0
41
220
1.93
3.64
1.4
1.2
—
—
—
0
0
26
117
2.28
3.62
1.1
1.2
—
—
—
0
0
12
30
4.06
3.61
1.3
1.2
—
—
—
0
0
8
13
6.22
3.51
8.0
6.3
—
—
—
0
0
49
283
1.79
3.47
3.8
2.9
—
—
—
0
0
13
344
0.36
3.47
1.2
1.3
—
—
—
0
0
43
239
1.86
3.44
2.6
3.0
—
—
—
0
0
524
4860
1.51
3.40
4.8
4.4
4.34
4.53
mmol/l
3.89
487
4443
7
10
7.06
3.37
1.3
1.3
—
—
—
0
0
194
1538
1.38
3.32
6.3
4.0
—
—
—
0
0
12
33
3.69
3.30
1.2
1.2
—
—
—
0
0
13
40
3.30
3.15
1.7
1.7
36.90
35.34
%
0.10
13
40
12
37
3.29
2.94
1.5
1.9
587.00
559.59
e6/l
0.10
12
37
530
4962
1.48
2.92
5.4
5.0
2.50
2.67
mmol/l
4.03
489
4493
25
122
2.09
2.91
1.5
1.4
238.31
282.36
ug/g
0.46
13
72
6
9
6.72
2.87
3.8
6.0
—
—
—
0
0
12
38
3.20
2.86
1.5
1.3
—
—
—
0
0
12
38
3.20
2.86
1.5
1.3
3.20
2.74
g/l
—
7
23
12
38
3.20
2.86
1.5
1.3
10.33
7.47
g/l
—
7
23
12
38
3.20
2.86
1.5
1.3
0.58
0.47
g/l
—
7
23
8
18
4.49
2.80
1.0
1.0
—
—
—
0
0
8
18
4.49
2.80
1.8
1.3
—
—
—
0
0
161
1269
1.36
2.80
1.4
1.3
—
—
—
0
0
501
4655
1.40
2.76
4.3
4.0
1.37
1.27
mmol/l
2.07
457
4182
11
34
3.27
2.73
1.3
1.1
—
—
—
0
0
13
48
2.75
2.73
1.1
1.2
—
—
—
0
0
516
4823
1.42
2.71
4.6
4.4
1.35
1.43
mmol/l
3.73
473
4373
41
244
1.73
2.67
1.2
1.3
—
56.99
—
0
16
62
412
1.56
2.64
8.3
3.6
—
—
—
0
0
10
30
3.37
2.61
2.5
4.8
—
—
—
0
0
9
227
0.39
2.60
1.4
1.3
—
—
—
0
0
12
44
2.76
2.56
1.7
1.6
8.63
10.57
%
0.86
12
44
12
42
2.89
2.56
1.0
1.2
—
—
—
0
0
5
7
7.19
2.55
1.2
1.0
—
—
—
0
0
264
2260
1.29
2.53
4.8
5.0
2.14
2.71
ug/l
0.98
234
1993
69
475
1.51
2.51
1.6
1.4
—
—
—
0
0
18
84
2.18
2.37
2.0
1.3
—
—
—
0
0
26
140
1.89
2.35
2.1
2.4
203.01
93.95
ug/min
0.30
15
85
11
40
2.78
2.28
2.0
2.9
40.68
39.73
%
—
5
22
7
18
3.92
2.25
1.1
1.5
—
—
—
0
0
138
1706
0.75
2.24
3.0
2.9
—
—
—
0
0
5
9
5.59
2.21
1.4
2.6
—
—
—
0
0
12
48
2.53
2.19
1.2
1.2
—
—
—
0
0
8
24
3.36
2.18
1.3
1.3
147.63
136.79
nmol/l
—
8
24
6
14
4.32
2.15
1.0
1.1
—
—
—
0
0
11
42
2.65
2.15
1.0
1.2
—
—
—
0
0
12
50
2.43
2.03
1.2
1.4
—
—
—
0
0
12
50
2.43
2.03
1.0
1.2
—
—
—
0
0
10
38
2.66
2.01
1.4
1.8
—
—
—
0
0
18
91
2.01
1.97
1.3
1.3
—
—
—
0
0
6
16
3.78
1.94
1.2
1.0
1831.83
1462.31
miu/ml
—
6
16
9
33
2.75
1.93
2.0
4.2
—
—
—
0
0
5
12
4.19
1.82
1.0
1.0
—
—
—
0
0
15
74
2.05
1.76
5.1
2.5
—
—
—
0
0
6
18
3.36
1.75
1.8
3.2
44183.33
38850.00
ug/l
—
6
18
6
18
3.36
1.75
3.3
1.8
95.50
57.11
ug/l
—
6
18
12
54
2.25
1.75
1.1
1.1
—
—
—
0
0
8
30
2.69
1.73
1.8
1.4
—
—
—
0
0
7
24
2.94
1.72
1.1
1.3
—
—
—
0
0
5
13
3.87
1.72
1.2
1.1
—
—
—
0
0
10
42
2.40
1.62
3.8
3.9
—
—
—
0
0
5
14
3.59
1.62
1.0
1.1
—
—
—
0
0
5
14
3.59
1.62
1.0
1.0
—
—
—
0
0
7
26
2.71
1.58
3.0
2.4
9.11
10.23
mmol/l
—
7
26
11
50
2.22
1.57
1.0
1.2
—
—
nmol/l
—
0
0
10
44
2.29
1.56
1.4
1.1
1.55
1.26
nmol/l
—
10
39
5
15
3.35
1.52
1.4
2.7
—
—
—
0
0
5
15
3.35
1.52
1.2
1.5
—
—
—
0
0
7
27
2.61
1.52
2.1
1.6
0.05
0.10
e9/l
—
7
27
24
148
1.65
1.46
1.5
1.6
—
—
—
0
0
82
646
1.31
1.44
1.3
1.3
—
—
—
0
0
24
150
1.62
1.40
7.1
4.4
—
—
—
0
0
35
242
1.47
1.33
2.7
2.6
—
—
—
0
0
5
19
2.64
1.22
1.8
2.1
4.10
3.30
ug/l
—
5
13
0
34
0.00
1.16
0.0
1.1
—
10.44
—
0
11
5
111
0.45
1.14
1.8
1.7
—
—
—
0
0
11
58
1.91
1.12
1.0
1.3
—
—
—
0
0
66
524
1.29
1.12
1.6
1.3
—
—
—
0
0
5
21
2.39
1.09
1.0
1.0
238.60
185.71
mmol/24h
—
5
21
10
179
0.55
1.06
1.2
1.1
—
—
—
0
0
5
22
2.28
1.03
2.0
1.7
14.98
12.77
umol/l
—
5
15
5
23
2.18
0.98
1.2
2.2
835.40
1921.13
u/ml
—
5
23
0
30
0.00
0.97
0.0
1.4
—
—
—
0
0
0
30
0.00
0.97
0.0
1.4
—
—
—
0
0
35
259
1.37
0.97
1.3
1.2
—
—
—
0
0
10
54
1.87
0.97
1.1
1.2
—
—
—
0
0
0
31
0.00
0.96
0.0
1.5
—
—
—
0
0
53
424
1.27
0.88
1.3
1.5
—
—
—
0
0
8
47
1.71
0.81
1.0
1.1
—
—
—
0
0
10
59
1.71
0.76
1.6
1.8
—
—
—
0
0
49
397
1.25
0.76
2.4
2.1
13.15
13.10
nmol/l
0.01
42
362
148
1329
1.15
0.75
1.5
1.6
1.40
1.37
mmol/l
0.16
126
1077
11
67
1.65
0.75
1.1
1.1
6.20
4.39
u/ml
—
5
31
9
54
1.68
0.74
1.1
1.2
—
—
—
0
0
5
24
2.09
0.74
1.0
3.5
192.00
126.08
nmol/l
—
5
24
11
169
0.64
0.70
1.7
1.6
—
—
—
0
0
5
27
1.86
0.68
5.2
2.2
—
—
—
0
0
5
28
1.79
0.66
1.2
1.5
51.82
25.56
u/l
—
5
21
8
51
1.58
0.60
1.4
2.9
4.96
3.46
nmol/l
—
8
51
20
152
1.33
0.52
11.0
8.7
—
—
—
0
0
6
40
1.50
0.51
1.2
1.2
—
—
—
0
0
10
68
1.48
0.47
2.3
2.7
—
—
—
0
0
9
127
0.70
0.43
1.1
1.1
—
—
—
0
0
51
444
1.16
0.43
1.6
1.5
—
—
—
0
0
5
32
1.57
0.42
2.2
1.8
13.10
13.10
%
—
5
32
11
79
1.40
0.41
1.2
1.8
329.18
314.84
mu/l
0.09
11
73
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.5
—
—
—
0
0
38
327
1.17
0.38
1.3
1.4
—
—
—
0
0
21
171
1.24
0.36
2.5
3.0
37.52
78.14
u/ml
0.68
21
165
143
1343
1.08
0.35
2.9
3.0
0.68
0.80
ug/l
1.06
104
924
7
56
1.25
0.29
1.4
1.2
—
—
—
0
0
7
57
1.23
0.29
1.7
1.1
—
—
—
0
0
7
57
1.23
0.29
1.7
1.1
—
—
—
0
0
10
77
1.30
0.26
2.5
2.6
19.23
23.60
u/ml
—
10
77
12
148
0.81
0.24
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
16.23
—
0
10
25
226
1.11
0.15
1.1
1.2
97.89
148.67
iu/ml
0.32
11
88
27
284
0.95
0.06
1.4
1.3
—
—
—
0
0
14
130
1.08
0.04
2.1
1.6
46.64
40.69
nmol/l
0.56
14
124
10
97
1.03
0.00
2.3
1.6
241.30
231.35
pmol/l
—
10
89
0
7
0.00
0.00
0.0
1.0
—
6.58
—
0
7
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
4.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
0.34
—
0
5
0
5
0.00
-0.00
0.0
4.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
96
0.94
-0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
35.20
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
9.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_DISCITIS and mortality.

Females

Parameter HR [95% CI] p-value
M13_DISCITIS 2.337 [1.84, 2.97] < 0.001
Birth year 0.997 [0.99, 1.01] 0.524

During the follow-up period (1.1.1998 — 31.12.2019), 358 out of 1285 females with M13_DISCITIS died.

Males

Parameter HR [95% CI] p-value
M13_DISCITIS 2.407 [1.94, 2.98] < 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 569 out of 1892 males with M13_DISCITIS died.

Mortality risk

Mortality risk for people of age

years, who have M13_DISCITIS.

N-year risk Females Males
1 0.203% 0.437%
5 1.306% 2.524%
10 3.654% 6.535%
15 7.338% 12.408%
20 12.465% 20.51%

Relationships between endpoints

Index endpoint: M13_DISCITIS – Discitis, unspecified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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