Drug-induced osteoporosis with pathological fracture

OSTPOPATFRACTURE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M80.4#
  • Cause of death: ICD-10 M80.4#

2 out of 7 registries used, show all original rules.

576

4. Check minimum number of events

None

576

5. Include endpoints

None

576

6. Filter based on genotype QC (FinnGen only)

562

Control definitions (FinnGen only)

Control exclude
OSTEOPOROSIS_FRACTURE_FG

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M80
Name in latin
Osteoporosis e medicamento cum fractura pathologica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2573 1758 796
Only index persons 2250 1568 682
Unadjusted period prevalence (%)
Whole population 0.04 0.05 0.02
Only index persons 0.05 0.06 0.03
Median age at first event (years)
Whole population 70.33 71.59 67.62
Only index persons 70.23 71.36 67.63

-FinnGen-

Key figures

All Female Male
Number of individuals 562 396 166
Unadjusted period prevalence (%) 0.12 0.14 0.08
Median age at first event (years) 69.19 68.77 70.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
576
Matched controls
5760
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
+∞
307.7
576
*
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
19.2
267.9
264
243
M05BX04
ATC
denosumab; parenteral
19.9
265.6
252
217
318
Kela drug reimbursment
Teriparatide
561.6
227.7
212
6
H05AA02
ATC
teriparatide; parenteral
511.1
213.2
200
6
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
33.3
210.5
142
56
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
26.2
192.0
142
71
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
56.3
184.4
106
23
M05BA04
ATC
alendronic acid; oral
11.5
183.7
257
377
L04AX01
ATC
azathioprine; systemic
19.1
176.5
153
107
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
10.8
170.2
245
369
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
10.2
162.3
247
396
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
15.2
157.6
502
1776
L95
ICPC
Osteoporosis
14.1
142.3
146
135
L04AX03
ATC
methotrexate; systemic
9.5
141.5
215
339
M81.9
ICD-10 Finland
Osteoporosis, unspecified
12.4
135.6
153
163
H02AB06
ATC
prednisolone; systemic
11.6
116.8
504
2170
P01BA02
ATC
hydroxychloroquine; oral
8.4
115.5
188
315
L04AA06
ATC
mycophenolic acid; systemic
31.1
113.5
76
28
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
9.5
109.2
151
208
H02AB09
ATC
hydrocortisone; systemic
17.2
104.7
91
62
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
12.8
104.5
110
104
L01BA01
ATC
methotrexate; systemic
12.9
101.4
106
99
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
8.8
96.4
140
203
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
10.4
96.3
119
141
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
6.0
92.6
233
590
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
8.1
92.1
144
227
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
11.8
91.4
101
102
H02AB07
ATC
prednisone; oral
6.0
88.5
213
516
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.1
77.9
244
730
M05BA07
ATC
risedronic acid; oral
9.6
74.4
95
116
L88
ICPC
Rheumatoid/seropositive arthritis
9.6
73.1
93
113
L04AA13
ATC
[U] leflunomide
12.5
72.5
75
68
M81.4
ICD-10 Finland
Drug-induced osteoporosis
273.6
72.1
72
*
N02AA05
ATC
oxycodone; systemic
4.7
70.2
240
760
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.5
68.8
277
990
J01MA12
ATC
levofloxacin; systemic
4.6
67.8
229
716
R50.9
ICD-10 Finland
Fever, unspecified
4.9
63.8
184
505
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.6
61.4
427
2201
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
12.5
61.4
63
56
H02AB04
ATC
methylprednisolone; systemic
4.7
61.3
186
530
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
60.9
156
387
ZX120
NOMESCO Finland
Intravenous
5.3
60.4
147
349
A07EC01
ATC
sulfasalazine; oral, rectal
6.0
59.0
120
242
S22.0
ICD-10 Finland
Fracture of thoracic vertebra
12.3
58.0
60
54
C03CA01
ATC
furosemide; systemic
3.9
57.4
321
1404
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.8
55.4
320
1421
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
8.5
55.2
76
101
L04AD01
ATC
ciclosporin; systemic
14.7
54.3
50
37
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
9.0
54.0
71
89
N02AX02
ATC
tramadol; systemic, rectal
3.9
53.4
382
1937
127
Kela drug reimbursment
Transplant complication
20.9
53.3
41
21
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
52.5
191
616
M05BB03
ATC
alendronic acid and colecalciferol; oral
9.6
50.9
63
73
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.6
50.6
300
1335
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.4
50.2
155
441
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
9.0
50.1
65
80
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.2
48.7
114
259
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
8.5
48.6
66
86
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.2
47.9
112
254
TPH04
NOMESCO Finland
Cathetrisation of vein
3.7
47.9
226
863
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.6
46.7
134
359
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
10.7
46.0
52
53
TGC00
NOMESCO Finland
Bronchial lavation
9.5
46.0
57
66
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
6.2
45.9
86
159
L04AB01
ATC
etanercept; parenteral
17.6
45.7
38
23
L04AA01
ATC
[U] ciclosporin
17.6
45.7
38
23
GD1AD
NOMESCO Finland
Thorax CT examination
5.8
45.2
91
180
M35.3
ICD-10 Finland
Polymyalgia rheumatica
6.1
44.5
84
156
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
8.4
43.7
60
79
SPAT1255
SPAT
Intravenous administration of medicine
5.5
43.3
93
195
S97
ICPC
Chronic ulcer skin
5.2
43.2
100
224
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
4.5
42.3
121
322
R03BB04
ATC
tiotropium bromide; inhalant
4.4
42.2
127
351
NF1AA
NOMESCO Finland
Hip X-ray examination
4.3
42.1
128
357
X59
ICD-10 Finland
Exposure to unspecified factor
3.6
41.9
189
692
N03AX16
ATC
[U] pregabalin
3.3
41.4
234
985
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.7
41.4
84
167
M54.5
ICD-10 Finland
Low back pain
3.2
41.0
303
1490
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
116.0
40.3
43
*
M81.8
ICD-10 Finland
Other osteoporosis
14.6
40.3
37
27
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.6
40.2
110
282
J01MA14
ATC
moxifloxacin; systemic
4.4
40.2
117
315
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
8.0
40.1
57
78
L28
ICPC
Limited function/disability (L)
3.4
40.1
201
784
J46
ICD-10 Finland
Status asthmaticus
8.8
39.9
52
64
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
15.5
39.4
35
24
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.7
39.1
159
542
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
4.2
39.0
123
351
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.9
39.0
138
428
J45.9
ICD-10 Finland
Asthma, unspecified
3.3
38.7
197
774
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
7.5
38.0
57
83
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
4.3
37.8
115
319
L03
ICPC
Low back symptom/complaint
3.1
37.5
248
1132
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
7.2
37.2
58
88
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
52.7
37.2
44
9
M01CB01
ATC
sodium aurothiomalate; parenteral
12.7
37.1
37
31
A07AA09
ATC
vancomycin; oral
14.4
36.8
34
25
A07AA02
ATC
nystatin; oral
4.8
36.7
91
215
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
3.0
36.6
330
1780
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.4
36.4
103
270
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
12.7
36.2
36
30
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
4.0
36.2
122
364
A46
ICD-10 Finland
Erysipelas
3.6
36.1
148
505
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
3.2
35.7
194
787
SPAT1254
SPAT
Administration of medicine
3.5
35.5
157
561
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
12.3
35.5
36
31
XG410
NOMESCO Finland
Flow-volume spirometry
6.5
35.4
61
103
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.5
35.3
155
552
A28
ICPC
Limited function/disability NOS
3.2
35.1
189
761
SPAT1229
SPAT
Assessment of need for aid
4.2
35.0
106
292
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
5.7
34.9
70
137
J01MA02
ATC
ciprofloxacin; systemic
2.9
34.5
311
1661
UJF32
NOMESCO Finland
Coloscopy
3.0
34.3
245
1155
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
9.7
33.4
40
44
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
5.6
33.4
68
135
J47
ICD-10 Finland
Bronchiectasis
8.6
33.3
44
55
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.1
33.1
104
294
J45.1
ICD-10 Finland
Nonallergic asthma
4.4
33.1
93
242
A41.9
ICD-10 Finland
Sepsis, unspecified
6.6
33.0
56
93
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
12.4
32.8
33
28
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
6.3
32.6
58
101
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.1
32.3
102
289
L04AB04
ATC
adalimumab; parenteral
9.9
32.1
38
41
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
7.1
32.0
50
76
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
12.5
31.9
32
27
ZXD05
NOMESCO Finland
Urgent procedure
2.8
31.4
240
1162
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
9.2
31.4
39
45
J01FF01
ATC
clindamycin; systemic
2.8
30.8
233
1119
X58
ICD-10 Finland
Exposure to other specified factors
3.4
30.4
130
451
L76
ICPC
Fracture: other
6.5
30.4
52
87
SPAT1216
SPAT
Assessment of functional ability
3.0
30.0
169
691
B01AB05
ATC
enoxaparin; parenteral
2.7
29.8
275
1456
J96.1
ICD-10 Finland
Chronic respiratory failure
8.6
29.8
39
48
E0000UV, ,
ATC
2.7
29.8
318
1809
NH3EA
NOMESCO Finland
Feet X-ray examination with load
8.8
29.4
38
46
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.0
29.2
95
274
S22.3
ICD-10 Finland
Fracture of rib
4.3
29.2
83
217
R03DA04
ATC
theophylline; systemic, rectal
4.8
29.1
70
160
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
4.3
29.1
84
222
NF3AA
NOMESCO Finland
Femur X-ray examination
7.0
29.0
46
71
J45.8
ICD-10 Finland
Mixed asthma
6.5
28.9
49
81
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.0
28.9
164
672
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.0
28.8
92
262
M05BA06
ATC
ibandronic acid; systemic
6.6
28.8
48
78
A02BC02
ATC
pantoprazole; systemic
3.4
28.7
477
3381
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
5.5
28.7
58
114
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.9
28.2
53
97
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
27.3
272
1479
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
10.2
27.0
31
32
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.4
26.8
113
387
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
7.2
26.7
41
61
R03BA05
ATC
fluticasone; inhalant
2.9
26.7
163
692
N03AX12
ATC
[U] gabapentin; oral
2.9
26.6
161
680
D64.9
ICD-10 Finland
Anaemia, unspecified
3.4
26.3
109
369
R06.0
ICD-10 Finland
Dyspnoea
2.6
26.2
233
1195
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.5
25.8
68
167
JN3AD
NOMESCO Finland
Abdominal CT examination
3.3
25.7
113
396
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.8
25.6
169
746
N02AJ06
ATC
codeine and paracetamol; systemic
2.5
25.5
311
1841
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
25.2
208
1025
AA1AD
NOMESCO Finland
CT of head and brain
2.5
24.9
228
1179
TQW11
NOMESCO Finland
Vacuum treatment of wound
7.6
24.9
36
50
SPAT1262
SPAT
Handing over of treatment supplies
2.8
24.8
156
669
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
6.5
24.4
41
67
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
24.3
143
592
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.6
24.1
208
1043
XW000
NOMESCO Finland
Bone marrow biopsy
5.0
24.1
55
120
WZC30
NOMESCO Finland
Teaching
2.8
23.9
145
610
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.9
23.8
78
225
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.8
23.7
57
130
JN4BD
NOMESCO Finland
Extensive body CT
3.2
23.6
107
381
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.1
23.4
68
180
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
4.6
23.4
59
140
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.4
23.3
311
1893
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
7.5
23.1
34
48
JN4AD
NOMESCO Finland
Body CT examination
3.3
23.0
100
347
M13.9
ICD-10 Finland
Arthritis, unspecified
3.7
22.8
79
237
WX892
NOMESCO Finland
Monitored bed care
3.7
22.6
77
228
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.9
22.6
123
486
NK6PA
NOMESCO Finland
Measurement of bone density from one location with X-ray
33.8
22.6
29
9
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.5
22.5
59
144
A05AA02
ATC
ursodeoxycholic acid; oral
8.7
22.4
29
35
WX002
NOMESCO Finland
Sedation and analgesia
2.6
22.3
174
828
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.1
22.1
66
178
Z2446
NOMESCO Finland
Social worker
3.8
21.9
72
208
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.3
21.9
95
329
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
4.6
21.9
55
130
R03AK08
ATC
formoterol and beclometasone; inhalant
4.7
21.7
52
118
Z3226
NOMESCO Finland
Physiotherapist
2.6
21.6
159
733
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.3
21.5
284
1703
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.3
21.4
338
2182
I50.9
ICD-10 Finland
Heart failure, unspecified
2.8
21.4
131
550
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
6.4
21.4
36
59
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.7
21.2
41
77
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
6.2
21.1
37
63
A06AD11
ATC
lactulose; oral
2.7
21.1
137
593
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
4.3
21.1
58
147
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
21.0
238
1334
NH1AD
NOMESCO Finland
Ankle and foot CT
7.7
21.0
30
41
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.7
20.9
137
596
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.6
20.9
52
122
WW500
NOMESCO Finland
Blood transfusion
4.6
20.8
51
118
R60.0
ICD-10 Finland
Localized oedema
2.9
20.8
118
476
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.3
20.7
315
1993
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.1
20.7
45
94
J01DB01
ATC
cefalexin; oral
3.5
20.7
516
4089
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.3
20.6
343
2252
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
20.3
181
911
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
20.2
155
727
UJF30
NOMESCO Finland
Ileoscopy through colon
3.0
20.1
100
374
ZX108
NOMESCO Finland
Inhalation
21.7
20.1
29
14
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.6
20.1
141
633
WW200
NOMESCO Finland
Immunization
6.4
20.1
34
56
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.8
19.9
64
182
H26.3
ICD-10 Finland
Drug-induced cataract
17.2
19.8
31
19
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.2
19.8
56
145
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.9
19.7
45
98
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
3.6
19.7
71
218
C03DA01
ATC
spironolactone; oral
2.8
19.7
116
476
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.6
19.7
141
639
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.2
19.4
34
58
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.1
19.2
56
148
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
5.9
19.2
35
62
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
19.2
100
384
A02BC05
ATC
esomeprazole; systemic
2.2
19.1
299
1892
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
6.5
19.1
32
52
N06AX21
ATC
duloxetine; oral
2.9
19.1
105
415
Z94.4
ICD-10 Finland
Liver transplant status
57.0
19.0
22
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.1
19.0
87
310
M80
ICD-10 Finland
Osteoporosis with pathological fracture
16.6
19.0
30
19
A07EC02
ATC
mesalazine; oral, rectal
4.1
19.0
55
145
N05CF01
ATC
zopiclone; oral
2.2
18.8
252
1497
R03AC12
ATC
salmeterol; inhalant
4.1
18.8
55
146
WX882
NOMESCO Finland
High dependency care
5.5
18.7
37
71
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.4
18.6
38
75
N30.0
ICD-10 Finland
Acute cystitis
2.6
18.6
137
628
R03BB01
ATC
ipratropium bromide; inhalant
4.2
18.6
51
129
TQW40
NOMESCO Finland
Remowal of suture of skin
3.4
18.6
73
237
R03DC03
ATC
montelukast; oral
2.6
18.5
135
615
W19
ICD-10 Finland
Unspecified fall
3.0
18.5
91
338
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
18.3
131
591
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.9
18.3
57
158
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
4.8
18.3
43
96
SPAT1211
SPAT
Application of soft bandage
3.1
18.2
85
306
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
5.5
18.2
36
69
TQW99
NOMESCO Finland
Other minor procedure on skin
3.8
18.1
59
169
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.8
18.1
34
62
SPAT1231
SPAT
Assessment of adjustments needed in living environment
6.1
18.1
32
55
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.9
18.0
56
155
ZXE00
NOMESCO Finland
One hour or less
2.2
18.0
265
1626
M54.6
ICD-10 Finland
Pain in thoracic spine
3.3
18.0
72
236
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.5
18.0
67
210
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
18.8
17.9
27
15
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.3
17.9
202
1114
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.2
17.9
50
128
R5110, ,
SPAT
3.4
17.8
70
227
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
15.2
17.8
29
20
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.3
17.7
47
116
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.6
17.6
43
99
TPH07
NOMESCO Finland
Cathetrisation of artery
2.8
17.6
99
395
SPAT1263
SPAT
Sampling
2.1
17.6
289
1846
TK800
NOMESCO Finland
Hemodialysis
7.3
17.5
26
37
S18
ICPC
Laceration/cut
2.1
17.5
320
2129
A07EA06
ATC
budesonide; oral, local oral
4.3
17.4
46
113
B01AA03
ATC
warfarin; systemic
2.4
17.4
150
737
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
5.3
17.4
36
72
C07AB07
ATC
bisoprolol; oral
2.1
17.3
349
2404
XF600
NOMESCO Finland
Bloodpressure measurement
3.4
17.3
67
215
R03AC02
ATC
salbutamol; inhalant
2.2
17.2
364
2552
R03AC13
ATC
formoterol; inhalant
3.6
17.2
60
180
M05BA01
ATC
etidronic acid; systemic
16.6
17.2
27
17
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.0
17.1
51
137
K83.0
ICD-10 Finland
Cholangitis
7.8
17.1
24
32
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
18.1
17.1
26
15
R60.9
ICD-10 Finland
Oedema, unspecified
3.7
17.1
58
171
L29
ICPC
Musculoskeletal sympt/complt other
3.0
16.9
80
290
JJC00
NOMESCO Finland
Allogenic transplantation of liver
65.4
16.8
19
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.9
16.8
38
82
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.9
16.7
26
39
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.7
16.7
107
456
Z3231
NOMESCO Finland
Registered nurse
2.2
16.7
200
1126
WX872
NOMESCO Finland
Intensive care
3.9
16.6
51
140
M48.0
ICD-10 Finland
Spinal stenosis
2.5
16.6
120
543
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
5.6
16.5
32
60
R4110
NOMESCO Finland
Physiotherapy
2.2
16.5
208
1192
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
4.2
16.3
45
114
TQW80
NOMESCO Finland
Local dermatologic skincare
5.5
16.3
32
61
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.1
16.2
72
251
A01
ICPC
Pain general/multiple sites
2.8
16.2
90
356
M79.6
ICD-10 Finland
Pain in limb
2.1
16.1
295
1941
L04AD02
ATC
tacrolimus; systemic
25.3
16.1
22
9
R03AC03
ATC
terbutaline; inhalant
2.6
16.1
113
503
R11
ICD-10 Finland
Nausea and vomiting
3.0
16.1
80
298
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
6.4
16.1
27
44
EBA10
NOMESCO Finland
Operative extraction of tooth
3.0
16.0
76
276
J05AB11
ATC
valaciclovir; oral
2.5
15.9
121
559
M81.0
ICD-10 Finland
Postmenopausal osteoporosis
4.3
15.9
42
103
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.5
15.8
118
541
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
15.7
65
217
XKD00
NOMESCO Finland
Uroflowmetry
2.7
15.7
97
405
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
15.7
105
457
A04
ICPC
Weakness/tiredness general
2.5
15.6
113
510
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
3.8
15.5
50
142
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.3
15.5
62
203
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.2
15.5
64
214
EBA15
NOMESCO Finland
Extraction of multiple teeth
4.6
15.4
38
88
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
7.2
15.4
23
33
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
24.1
15.2
21
9
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.7
15.2
36
81
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.8
15.1
47
130
R03BA01
ATC
beclometasone; inhalant
2.5
15.1
111
504
R4120
NOMESCO Finland
Occupational therapy
3.2
15.1
64
217
R01AD08
ATC
fluticasone; nasal
2.1
15.0
188
1069
R52.9
ICD-10 Finland
Pain, unspecified
2.8
14.9
85
340
J02AC01
ATC
fluconazole; systemic
2.0
14.9
265
1711
UKC02
NOMESCO Finland
Cystoscopy
2.4
14.9
115
534
N03AX09
ATC
lamotrigine; oral
4.2
14.8
41
104
M05BX03
ATC
strontium ranelate; oral
19.0
14.8
22
12
R52.2
ICD-10 Finland
Other chronic pain
4.0
14.8
44
118
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
6.3
14.8
25
41
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.1
14.8
42
109
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.0
14.7
71
260
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.7
14.7
35
79
K08.3
ICD-10 Finland
Retained dental root
3.1
14.7
66
232
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.0
14.5
43
115
J01FA06
ATC
roxithromycin; oral
2.0
14.4
273
1796
A01AB09
ATC
miconazole; local oral
2.7
14.4
85
346
L02
ICPC
Back symptom/complaint
2.7
14.4
83
334
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
4.9
14.4
32
68
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
14.3
251
1609
SAA03
NOMESCO Finland
Extended examination of mouth
2.0
14.2
245
1558
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.3
14.2
38
94
B01AB04
ATC
dalteparin; parenteral
3.6
14.2
49
146
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
4.3
14.1
37
90
K50.0
ICD-10 Finland
Crohn disease of small intestine
6.9
14.1
22
33
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.3
14.1
57
188
N06AA09
ATC
amitriptyline; systemic
2.6
14.0
89
376
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.5
14.0
50
152
SAA04
NOMESCO Finland
Special examination of mouth
3.5
14.0
50
152
M80.5
ICD-10 Finland
Idiopathic osteoporosis with pathological fracture
20.7
13.9
20
10
UJF92
NOMESCO Finland
Capsular endoscopy
5.5
13.8
27
51
TKC20
NOMESCO Finland
Catheterisation of bladder
3.2
13.8
59
201
NFJ60
NOMESCO Finland
Internal fixation of fracture of other parts of femur with intramedullary nail
15.2
13.7
22
15
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
5.6
13.6
26
48
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
10.4
13.6
26
26
A02BA02
ATC
ranitidine; systemic
2.1
13.5
156
854
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
13.5
70
266
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.7
13.5
44
126
K05.18
ICD-10 Finland
Chronic gingivitis
3.3
13.5
54
177
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.8
13.4
31
68
E000003, ,
ATC
3.9
13.4
41
112
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.4
13.3
34
81
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.8
13.3
41
113
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.2
13.2
128
653
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.8
13.1
71
276
R02
ICPC
Shortness of breath/dyspnoea
2.4
13.1
104
487
SPAT1234
SPAT
Support of social functional capacity
3.3
13.1
51
164
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.0
13.1
60
213
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.8
13.0
24
43
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
13.0
205
1256
R03AK03
ATC
[U] fenoterol and ipratropium bromide
3.3
13.0
51
165
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
11.9
12.9
23
20
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
11.9
12.9
23
20
S32.7
ICD-10 Finland
Multiple fractures of lumbar spine and pelvis
10.8
12.9
24
23
R81
ICPC
Pneumonia
4.2
12.8
35
88
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.4
12.8
99
459
SPAT1172
SPAT
Guidance concerning hydration
5.1
12.7
27
55
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.1
12.7
157
880
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.9
12.7
62
228
A07DA03
ATC
loperamide; oral
4.1
12.6
35
89
ZZA00
NOMESCO Finland
Split skin graft
4.4
12.6
32
76
L89
ICD-10 Finland
Decubitus ulcer and pressure area
5.4
12.6
25
48
A41.8
ICD-10 Finland
Other specified sepsis
5.8
12.5
23
41
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
12.5
231
1489
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.5
12.4
44
133
Z3229
NOMESCO Finland
Other healthcare associate professional
2.7
12.4
70
278
SPAT1325
SPAT
Vaccination
1.9
12.3
238
1554
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.6
12.1
73
300
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.4
12.1
24
46
R03AK07
ATC
formoterol and budesonide; inhalant
2.1
12.0
135
728
PAW37
NOMESCO Finland
Biopsy of temporal artery
13.8
12.0
20
15
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.2
12.0
126
662
A03CA02
ATC
clidinium and psycholeptics; oral
3.0
12.0
56
201
A02BC03
ATC
lansoprazole; oral
1.9
11.9
212
1344
ZXA10
NOMESCO Finland
Bilateral
2.1
11.8
146
815
Z01.2
ICD-10 Finland
Dental examination
1.9
11.8
268
1836
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
5.1
11.8
25
51
49300
ICD-8 Finland
Asthma, bronchiale
4.9
11.8
26
55
R03BA02
ATC
budesonide; inhalant
2.1
11.8
133
719
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.5
11.7
82
362
A08
ICPC
Swelling
3.0
11.7
55
198
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
66.3
11.6
13
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
66.3
11.6
13
*
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
5.4
11.6
23
44
N02BF01
ATC
gabapentin; oral
2.6
11.6
71
294
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
9.5
11.6
23
25
ZXA00
NOMESCO Finland
Right side
1.9
11.6
200
1254
S92.3
ICD-10 Finland
Fracture of metatarsal bone
3.9
11.6
35
95
NHQ40
NOMESCO Finland
Amputation of toe
5.9
11.6
21
37
K02.1
ICD-10 Finland
Caries of dentine
1.8
11.5
330
2423
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.7
11.5
27
60
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.0
11.5
25
52
N02AC04
ATC
dextropropoxyphene; oral
3.6
11.5
38
110
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
3.4
11.5
42
130
N05BA04
ATC
oxazepam; oral
1.9
11.4
177
1070
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.4
11.4
29
69
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.1
11.4
133
727
S20.2
ICD-10 Finland
Contusion of thorax
3.4
11.3
41
126
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.8
11.3
59
225
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.7
11.3
26
57
R03DC01
ATC
zafirlukast; oral
4.9
11.3
25
53
WX725
NOMESCO Finland
Noninvasive ventilation
3.1
11.3
48
163
M70.2
ICD-10 Finland
Olecranon bursitis
4.2
11.3
30
74
Z2221
NOMESCO Finland
Medical doctor
1.9
11.3
176
1066
M70.6
ICD-10 Finland
Trochanteric bursitis
2.2
11.2
114
591
K50.9
ICD-10 Finland
Crohn disease, unspecified
8.3
11.2
24
30
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.0
11.2
52
186
SAA02
NOMESCO Finland
Basic examination of mouth
1.9
11.1
375
2882
5BA08, ,
NOMESCO Finland
11.5
11.1
20
18
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
5.2
11.1
23
46
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
4.2
11.1
30
75
WX212
NOMESCO Finland
Femoral plexus blockade
4.6
11.1
26
58
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
5.0
11.0
24
50
A02BC01
ATC
omeprazole; systemic
1.9
11.0
190
1188
ZXE20
NOMESCO Finland
More than three and less than five hours
2.2
11.0
102
509
SPAT1167
SPAT
Insertion of urinary catheter
4.0
11.0
31
80
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.4
10.9
27
63
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
10.9
83
381
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
28.6
10.8
14
5
XG466
NOMESCO Finland
Sleep oxymetry
3.9
10.7
32
86
H25.8
ICD-10 Finland
Other senile cataract
2.3
10.7
93
452
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
61.2
10.7
12
*
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.2
10.6
22
44
B01AB10
ATC
tinzaparin; parenteral
2.4
10.6
81
372
K50.1
ICD-10 Finland
Crohn disease of large intestine
9.4
10.6
21
23
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
4.9
10.6
23
48
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.2
10.5
42
137
H04.10
ICD-10 Finland
Dry eye syndrome
2.3
10.5
88
420
R53
ICD-10 Finland
Malaise and fatigue
1.9
10.5
163
981
L86
ICPC
Back syndrome with radiating pain
2.9
10.5
52
193
A03FA01
ATC
metoclopramide; systemic, rectal
1.9
10.4
159
951
M54
ICD-10 Finland
Dorsalgia
2.3
10.4
85
401
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
12.3
10.4
18
15
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
16.4
10.4
16
10
J20
ICD-10 Finland
Acute bronchitis
2.4
10.4
80
369
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
10.3
261
1827
M25.5
ICD-10 Finland
Pain in joint
1.8
10.3
211
1387
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.1
10.3
44
150
WZA90
NOMESCO Finland
Other medical or dental certificate
1.9
10.3
154
916
WX110
NOMESCO Finland
Infiltration anesthesia
1.9
10.2
408
3261
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.3
10.2
84
398
WX213
NOMESCO Finland
Lower leg blockade
13.4
10.2
17
13
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.8
10.2
51
190
K03.66
ICD-10 Finland
Tooth plaque
2.8
10.1
54
208
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
8.7
10.1
21
25
A11CC03
ATC
alfacalcidol; systemic
4.9
10.1
22
46
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.7
10.1
23
50
L17
ICPC
Foot/toe symptom/complaint
1.8
10.1
196
1266
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.7
10.1
32
90
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.6
10.0
33
95
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.5
10.0
35
105
ND1BA
NOMESCO Finland
Wrist extensive X-ray examination
4.3
10.0
26
63
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
7.8
10.0
22
29
H26.4
ICD-10 Finland
After-cataract
2.2
9.9
88
430
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.1
9.9
105
551
S72.2
ICD-10 Finland
Subtrochanteric fracture
12.5
9.9
17
14
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.5
9.9
24
55
TAB00
NOMESCO Finland
Lumbar puncture
3.2
9.9
40
132
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
10.9
9.8
18
17
J45
ICD-10 Finland
Asthma
2.4
9.8
74
338
R06AE07
ATC
cetirizine; oral
1.8
9.7
264
1877
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
56.0
9.7
11
*
NA2AD
NOMESCO Finland
Thoracic spine CT examination
11.6
9.6
17
15
S72.0
ICD-10 Finland
Fracture of neck of femur
3.2
9.6
39
129
ZX140
NOMESCO Finland
Intra articular
10.3
9.6
18
18
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.9
9.6
45
162
J01FA09
ATC
clarithromycin; systemic
1.8
9.6
197
1291
TPH40
NOMESCO Finland
Insertion of a long peripheral venous catheter
15.4
9.6
15
10
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
3.8
9.5
29
79
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
9.5
119
663
N02BE01
ATC
paracetamol; systemic, rectal
2.6
9.5
531
4704
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
9.5
241
1677
J01AA02
ATC
doxycycline; systemic
2.0
9.5
469
3959
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
9.4
55
222
S22.4
ICD-10 Finland
Multiple fractures of ribs
5.3
9.4
19
37
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
9.4
139
820
N06AX16
ATC
venlafaxine; oral
2.1
9.4
93
475
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
22.1
9.4
13
6
P01AB01
ATC
metronidazole; oral, rectal
1.7
9.4
257
1826
XQ800
NOMESCO Finland
Prick test
2.6
9.3
55
223
WX320
NOMESCO Finland
Spinalanesthesy
1.8
9.3
168
1055
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.2
9.3
37
121
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
9.3
54
218
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.7
9.3
51
200
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.7
9.3
52
206
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
2.1
9.2
102
543
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.8
9.2
46
171
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.2
9.2
36
116
J01FA10
ATC
azithromycin; systemic
1.7
9.2
334
2559
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.5
9.2
60
256
A06AC51
ATC
ispaghula, combinations; oral
2.9
9.2
45
166
E000006, ,
ATC
2.5
9.1
57
238
A07EA02
ATC
hydrocortisone; rectal
4.7
9.1
21
46
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.9
9.1
20
42
M79.0
ICD-10 Finland
Rheumatism, unspecified
3.2
9.1
36
117
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
4.2
9.1
24
59
X57
ICD-10 Finland
Unspecified privation
4.3
9.0
23
55
J01CA04
ATC
amoxicillin; systemic
2.0
9.0
469
3982
B01AF02
ATC
apixaban; oral
2.1
8.9
97
513
RS220, ,
NOMESCO Finland
8.1
8.9
19
24
L01BB02
ATC
mercaptopurine; oral
8.1
8.9
19
24
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
7.0
8.9
21
31
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.0
8.9
19
39
R03AK11
ATC
formoterol and fluticasone; inhalant
3.9
8.9
26
69
S72.3
ICD-10 Finland
Fracture of shaft of femur
9.7
8.8
17
18
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
9.7
8.8
17
18
L84
ICD-10 Finland
Corns and callosities
3.2
8.8
35
114
K51.5
ICD-10 Finland
Left sided colitis
4.2
8.8
23
56
M54.8
ICD-10 Finland
Other dorsalgia
3.3
8.8
34
109
W22
ICD-10 Finland
Striking against or struck by other object(s)
2.9
8.8
41
147
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.4
8.8
63
281
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.6
8.8
29
84
SPF00
NOMESCO Finland
Reparation of dental prosthesis without impressions
3.5
8.7
30
89
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
6.8
8.7
21
32
B80
ICPC
Iron deficiency anaemia
4.4
8.7
22
52
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
7.8
8.7
19
25
S52.0
ICD-10 Finland
Fracture of upper end of ulna
4.5
8.7
21
48
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
4.7
8.6
20
44
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.9
8.6
42
154
WX730
NOMESCO Finland
Conventional respirator
8.4
8.6
18
22
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.4
8.6
63
283
B02.9
ICD-10 Finland
Zoster without complication
2.5
8.6
55
232
RD210, ,
NOMESCO Finland
7.1
8.6
20
29
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
10.2
8.6
16
16
R28
ICPC
Limited function/disability (R)
6.6
8.6
21
33
WVA20, ,
SPAT
3.8
8.5
26
71
H26.02
ICD-10 Finland
Presenil cataract
3.8
8.5
26
71
QDB10, ,
SPAT
4.3
8.5
22
53
D07AC13
ATC
mometasone; topical
1.8
8.5
179
1173
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.7
8.5
307
2329
SFA10
NOMESCO Finland
One-surface restoration
1.7
8.5
305
2310
M48.5
ICD-10 Finland
Collapsed vertebra, not elsewhere classified
28.0
8.5
11
*
L04AA17
ATC
[U] adalimumab
28.0
8.5
11
*
SPAT1301
SPAT
No procedures
1.7
8.5
204
1388
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.6
8.5
28
81
J05AB01
ATC
aciclovir; systemic
1.8
8.5
147
910
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.7
8.4
236
1673
JJ5AT, ,
NOMESCO Finland
91.3
8.4
9
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
8.4
59
260
ZZH31
NOMESCO Finland
Bone allograft, small pieces
8.0
8.4
18
23
R4110, ,
SPAT
2.3
8.4
69
326
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
4.1
8.4
23
58
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
13.0
8.4
14
11
R05
ICD-10 Finland
Cough
1.8
8.4
141
864
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
8.7
8.4
17
20
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
8.7
8.4
17
20
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
3.6
8.3
27
77
J01FA15
ATC
telithromycin; oral
2.2
8.3
70
334
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
8.3
64
294
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
3.9
8.3
24
63
R4180
NOMESCO Finland
Podiatric therapy
7.2
8.3
19
27
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.8
8.3
164
1055
K59.0
ICD-10 Finland
Constipation
2.6
8.2
50
206
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
3.1
8.2
35
119
Z50.1
ICD-10 Finland
Other physical therapy
2.7
8.2
46
182
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.3
8.2
31
98
S81.0
ICD-10 Finland
Open wound of knee
4.6
8.2
19
42
A06AH03
ATC
naloxegol; oral
4.9
8.2
18
38
A02BA03
ATC
famotidine; systemic
3.0
8.2
36
125
ZXA05
NOMESCO Finland
Left side
1.8
8.1
172
1127
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.6
8.1
47
189
Z71.8
ICD-10 Finland
Other specified counselling
1.7
8.1
180
1195
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
8.1
77
386
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
17.5
8.1
12
7
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
33.9
8.1
10
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
8.1
95
516
R96
ICPC
Asthma
2.2
8.1
73
359
K50.8
ICD-10 Finland
Other Crohn disease
6.4
8.1
20
32
WZA10
NOMESCO Finland
Extensive medical or dental certificate
6.4
8.1
20
32
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
10.2
8.1
15
15
L74
ICPC
Fracture: hand/foot bone
4.2
8.1
21
51
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
22.4
8.0
11
5
WZA00
NOMESCO Finland
Concise certificate
2.6
8.0
46
184
R4190
NOMESCO Finland
Nutritional therapy
3.5
8.0
28
84
W10
ICD-10 Finland
Fall on and from stairs and steps
2.8
8.0
40
149
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
8.0
236
1692
A10AC01
ATC
insulin (human); parenteral
2.5
8.0
52
222
D86.0
ICD-10 Finland
Sarcoidosis of lung
6.7
7.9
19
29
M81.5
ICD-10 Finland
Idiopathic osteoporosis
7.9
7.9
17
22
ZXX01
NOMESCO Finland
Extent of proceudre, 1 unit
13.3
7.9
13
10
M01AH01
ATC
celecoxib; oral
1.8
7.9
126
758
N06AX11
ATC
mirtazapine; oral
1.7
7.9
215
1509
R01AD09
ATC
mometasone; nasal
1.6
7.8
264
1954
J01DC02
ATC
cefuroxime; systemic
2.8
7.8
39
145
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.2
7.8
69
336
WX204
NOMESCO Finland
Axillary plexus blockaced
3.2
7.8
30
96
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
4.3
7.8
20
48
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.1
7.8
83
435
C01CA24
ATC
epinephrine; parenteral
2.6
7.8
45
181
C10AC01
ATC
colestyramine; oral
3.6
7.8
25
71
SPAT1260
SPAT
Consultation of another employee
1.9
7.8
117
691
SFA30
NOMESCO Finland
Three-surface restoration
1.7
7.8
246
1792
L04AA24
ATC
abatacept; parenteral
15.3
7.7
12
8
L99
ICPC
Musculoskeletal disease other
4.4
7.7
19
44
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
45.6
7.7
9
*
SCA02
NOMESCO Finland
Preventive oral health care
2.3
7.7
61
284
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.9
7.7
37
135
R06AX22
ATC
ebastine; oral
1.9
7.7
109
631
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
3.7
7.7
24
67
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.7
7.7
24
67
L75
ICPC
Fracture: femur
6.8
7.6
18
27
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
3.5
7.6
26
77
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
7.6
175
1171
TKC22
NOMESCO Finland
Catheterisation instruction
4.2
7.6
20
49
NF3BA
NOMESCO Finland
Femur extensive X-ray examination
25.4
7.6
10
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
7.6
148
945
SFC01
NOMESCO Finland
Additional procedure necessary for restorative treatment
1.7
7.6
158
1028
M06
ICD-10 Finland
Other rheumatoid arthritis
9.0
7.6
15
17
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.5
7.6
47
196
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.2
7.5
70
348
R03BA08
ATC
ciclesonide; inhalant
2.2
7.5
62
294
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
4.5
7.5
18
41
L50.8
ICD-10 Finland
Other urticaria
4.5
7.5
18
41
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.0
7.4
33
115
105
Kela drug reimbursment
Adrenal cortical hypofunction
81.1
7.4
8
*
N03AX14
ATC
levetiracetam; systemic
3.8
7.4
22
59
U07
ICPC
Urine symptom/complaint other
2.3
7.4
57
262
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.3
7.4
54
243
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.7
7.4
184
1257
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
11.1
7.3
13
12
NDG30
NOMESCO Finland
Fusion of wrist, total
11.1
7.3
13
12
H53.4
ICD-10 Finland
Visual field defects
4.2
7.3
19
46
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.4
7.3
50
218
K13.78
ICD-10 Finland
Other change in the oral mucosa
3.9
7.3
21
55
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
7.3
7
*
M31.1
ICD-10 Finland
Thrombotic microangiopathy
+∞
7.3
7
*
RS221, ,
NOMESCO Finland
5.9
7.3
19
33
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.6
7.3
43
175
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
16.0
7.2
11
7
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.2
7.2
28
90
D68.8
ICD-10 Finland
Other specified coagulation defects
7.4
7.2
16
22
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.6
7.2
17
38
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.3
7.2
57
265
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.0
7.2
20
51
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.6
7.2
23
65
R1250
NOMESCO Finland
Evaluation of functional capability
3.6
7.2
23
65
J01EA01
ATC
trimethoprim; systemic
1.7
7.2
178
1211
XCK00
NOMESCO Finland
Perimetry
2.4
7.2
48
207
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.5
7.2
24
70
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.9
7.2
34
123
C08DA01
ATC
verapamil; systemic
2.7
7.2
39
152
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
30.4
7.2
9
*
J04AB02
ATC
rifampicin; systemic
6.7
7.2
17
26
SHA02
NOMESCO Finland
Stomatognathic treatment, basic
2.5
7.1
45
189
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
7.1
134
845
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
4.1
7.1
19
47
WX202
NOMESCO Finland
Supraclavicular plexus blockade
6.2
7.1
18
30
J01CF05
ATC
flucloxacillin; systemic
2.5
7.1
44
183
S19
ICPC
Skin injury other
3.0
7.1
31
107
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.7
7.1
37
141
R03AL11
ATC
formoterol, glycopyrronium bromide and budesonide; inhalant
12.2
7.1
12
10
A69
ICPC
General and Unspecified, Other reason for encounter NEC
3.7
7.1
22
61
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
7.1
115
694
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.2
7.1
27
86
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.9
7.1
97
555
JF1AD
NOMESCO Finland
Small bowel CT
10.2
7.1
13
13
N02CA52
ATC
ergotamine, combinations excl. psycholeptics; oral
4.3
7.1
18
43
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
7.0
145
938
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
7.1
7.0
16
23
M47.9
ICD-10 Finland
Spondylosis, unspecified
3.1
7.0
28
92
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
6.0
7.0
18
31
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
7.0
71
366
A03
ICPC
Fever
1.9
6.9
90
505
NB1AD
NOMESCO Finland
Shoulder CT examination
4.1
6.9
19
48
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.9
125
778
K99
ICPC
Cardiovascular disease other
3.6
6.9
22
62
JAH00
NOMESCO Finland
Laparotomy
3.3
6.9
26
82
NA3BA
NOMESCO Finland
Lumbar spine extensive X-ray examination without contrast
14.0
6.9
11
8
ZX112
NOMESCO Finland
Subcutaneous
3.5
6.9
23
67
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
3.3
6.9
25
77
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
3.1
6.9
29
98
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
2.8
6.9
34
126
R33
ICD-10 Finland
Retention of urine
2.4
6.9
49
218
C08CA05
ATC
nifedipine; systemic
2.4
6.9
46
199
A03FA02
ATC
cisapride; oral, rectal
2.2
6.8
58
278
EB1WA, ,
NOMESCO Finland
11.1
6.8
12
11
R06.2
ICD-10 Finland
Wheezing
2.8
6.8
33
121
S32.8
ICD-10 Finland
Fracture of other and unspecified parts of lumbar spine and pelvis
6.2
6.8
17
28
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
5.8
6.8
18
32
M04AA01
ATC
allopurinol; systemic
2.0
6.8
82
449
SPAT1125
SPAT
Stoma care and guidance
4.3
6.8
17
40
Z09.4
ICD-10 Finland
Follow-up examination after treatment of fracture
2.5
6.8
43
181
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
40.5
6.8
8
*
M30.0
ICD-10 Finland
Polyarteritis nodosa
40.5
6.8
8
*
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
40.5
6.8
8
*
E23.03
ICD-10 Finland
Lack of ACTH
16.9
6.8
10
6
L01AA01
ATC
cyclophosphamide; systemic
16.9
6.8
10
6
I50.0
ICD-10 Finland
Congestive heart failure
2.2
6.8
55
259
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.9
6.7
32
116
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
7.3
6.7
15
21
J01DA01
ATC
[U] cefalexin
1.6
6.7
359
2929
N05BA01
ATC
diazepam; systemic, rectal
1.9
6.7
91
518
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
6.7
73
385
207
Kela drug reimbursment
Chronic arrhythmias
1.8
6.7
110
665
R35
ICD-10 Finland
Polyuria
2.4
6.7
48
214
R5130, ,
SPAT
22.8
6.7
9
*
I77.6
ICD-10 Finland
Arteritis, unspecified
22.8
6.7
9
*
D68.9
ICD-10 Finland
Coagulation defect, unspecified
22.8
6.7
9
*
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
22.8
6.7
9
*
E000001, ,
ATC
1.8
6.7
120
746
SFA20
NOMESCO Finland
Two-surface restoration
1.6
6.7
312
2467
XX3DW
NOMESCO Finland
Time consuming IT work
2.0
6.7
76
408
XF640, ,
NOMESCO Finland
3.3
6.6
25
79
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.4
6.6
46
202
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.0
6.6
28
95
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
6.6
53
248
-1, ,
NOMESCO Finland
1.6
6.6
181
1260
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
12.4
6.6
11
9
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
4.2
6.6
17
41
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
8.8
6.6
13
15
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
8.8
6.6
13
15
J01DA06
ATC
[U] cefuroxime
1.9
6.6
94
545
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
10.2
6.6
12
12
H20.1
ICD-10 Finland
Chronic iridocyclitis
7.0
6.5
15
22
M01AB55
ATC
diclofenac, combinations; oral
2.2
6.5
55
263
SPAT1210
SPAT
Application of cast or individual aid
2.7
6.5
34
130
A29
ICPC
General symptom/complaint other
1.9
6.5
88
501
R4130
NOMESCO Finland
Speech therapy
3.6
6.5
21
60
L84
ICPC
Back syndrome without radiat pain
2.6
6.5
37
148
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.8
6.5
120
752
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
7.5
6.4
14
19
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
7.5
6.4
14
19
B37.7
ICD-10 Finland
Candidal sepsis
70.6
6.4
7
*
M32
ICD-10 Finland
Systemic lupus erythematosus
70.6
6.4
7
*
S01EE01
ATC
latanoprost; ophthalmic
2.3
6.4
50
231
R01AD05
ATC
budesonide; nasal
2.2
6.4
53
251
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
6.4
159
1078
JN4CD
NOMESCO Finland
Very extensive body CT
2.8
6.4
31
114
D09
ICPC
Nausea
2.8
6.4
31
114
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.8
6.4
31
114
M01CB03
ATC
auranofin; oral
8.3
6.4
13
16
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
8.3
6.4
13
16
G35
ICD-10 Finland
Multiple sclerosis
6.1
6.3
16
27
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
11.2
6.3
11
10
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
11.2
6.3
11
10
H02AB08
ATC
triamcinolone; systemic
11.2
6.3
11
10
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.1
6.3
59
294
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.2
6.3
53
253
R63.4
ICD-10 Finland
Abnormal weight loss
2.8
6.3
30
109
3AC01, ,
NOMESCO Finland
9.4
6.3
12
13
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
6.3
28
98
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
18.3
6.3
9
5
J82
ICD-10 Finland
Pulmonary eosinophilia, not elsewhere classified
18.3
6.3
9
5
L04AA11
ATC
[U] etanercept
18.3
6.3
9
5
R51.80
ICD-10 Finland
Headache
1.8
6.3
93
545
A02BX02
ATC
sucralfate; oral
2.7
6.3
32
121
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
+∞
6.3
6
*
M08.9
ICD-10 Finland
Juvenile arthritis, unspecified
+∞
6.3
6
*
XF404
NOMESCO Finland
Ambulatory ECG
2.1
6.3
62
316
D07AC01
ATC
betamethasone; topical
1.6
6.3
212
1550
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.1
6.2
14
20
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
7.1
6.2
14
20
NDL52
NOMESCO Finland
Tenosynovectomy of hand
7.1
6.2
14
20
WX203
NOMESCO Finland
Infraclavicular plexus blockade
3.7
6.2
19
52
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
6.2
177
1240
SPAT1310
SPAT
Counselling related to known health issue
1.6
6.2
191
1363
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
27.0
6.2
8
*
H11.3
ICD-10 Finland
Conjunctival haemorrhage
2.7
6.2
34
133
E000002, ,
ATC
2.1
6.2
64
331
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
4.0
6.2
17
43
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
6.4
6.2
15
24
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
3.5
6.2
21
62
M01AH02
ATC
rofecoxib; oral
1.8
6.2
93
547
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.9
6.2
28
99
UJD02
NOMESCO Finland
Gastroscopy
2.5
6.2
37
152
WX199
NOMESCO Finland
Other local analgesia
3.0
6.1
27
94
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
4.2
6.1
16
39
S41.1
ICD-10 Finland
Open wound of upper arm
12.7
6.1
10
8
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
12.7
6.1
10
8
M35.1
ICD-10 Finland
Other overlap syndromes
12.7
6.1
10
8
N86
ICPC
Multiple sclerosis
12.7
6.1
10
8
WX290
NOMESCO Finland
Other blockage of nerve
1.6
6.1
228
1703
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
8.7
6.1
12
14
1XC02, ,
NOMESCO Finland
8.7
6.1
12
14
S81.9
ICD-10 Finland
Open wound of lower leg, part unspecified
6.8
6.1
14
21
SXC03
NOMESCO Finland
Other oral or dental procedure
6.8
6.1
14
21
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.6
6.1
34
135
SPAT1104
SPAT
Monitoring of emergency patient
2.3
6.1
45
204
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
10.2
6.1
11
11
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.4
6.1
21
63
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
6.1
6.0
15
25
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
3.1
6.0
25
84
S70
ICPC
Herpes zoster
3.1
6.0
25
84

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
266
641
6.85
114.74
6.9
4.9
1.04
1.04
mmol/l
0.12
245
577
494
2138
10.21
111.82
5.2
2.3
87.56
79.34
nmol/l
8.65
468
1874
217
449
7.15
108.67
2.0
3.0
63.76
66.73
g/l
5.20
187
401
203
409
7.12
103.94
1.7
2.6
—
—
—
0
0
195
380
7.25
103.10
5.0
3.0
9.16
10.42
g/l
2.49
189
348
495
2256
9.49
102.27
19.8
6.4
—
—
—
0
0
482
2196
8.32
97.72
18.4
5.9
0.61
0.68
%
2.26
466
2033
208
456
6.57
97.12
3.1
2.0
270.40
375.54
nmol/l
6.40
198
416
489
2275
8.61
96.31
19.4
6.2
8.60
8.65
%
0.12
474
2117
486
2264
8.34
95.04
18.5
5.9
2.29
2.82
%
6.67
469
2101
520
2594
11.33
94.15
15.8
6.3
1.22
1.22
mmol/l
0.02
438
2208
501
2423
9.20
93.31
17.5
5.8
0.63
0.58
e9/l
5.81
474
2087
486
2288
8.19
93.13
17.5
5.8
62.90
57.33
%
17.54
472
2130
489
2318
8.35
92.90
19.0
6.1
22.83
27.60
%
17.60
473
2158
501
2432
9.14
92.63
17.6
5.8
0.04
0.04
e9/l
0.05
473
2099
503
2473
9.16
90.98
17.8
5.9
1.68
1.91
e9/l
2.12
481
2185
507
2513
9.49
90.85
18.4
6.1
0.16
0.19
e9/l
3.13
478
2197
159
307
6.77
83.47
2.5
1.9
1.09
1.23
g/l
0.51
150
278
174
380
6.13
80.18
6.9
4.1
0.59
0.58
%
0.02
87
128
346
1350
4.91
78.81
8.5
4.1
—
—
—
0
0
242
716
5.10
78.41
3.4
1.9
—
—
—
0
0
519
2840
9.36
77.00
22.8
9.3
4.92
4.07
e9/l
11.88
499
2485
181
427
5.72
76.33
7.1
4.1
0.87
0.98
%
0.27
95
160
172
395
5.78
74.60
7.2
4.3
0.07
0.13
%
0.62
86
127
470
2402
6.20
74.04
14.4
5.5
1.22
1.22
mmol/l
0.11
450
2174
172
424
5.36
68.32
3.5
3.6
77.69
80.54
ng/l
0.18
147
371
161
375
5.57
68.24
7.2
4.4
0.03
0.90
%
0.55
68
108
205
594
4.81
66.77
3.6
2.7
2.21
1.84
%
1.58
182
527
109
178
7.32
66.46
2.0
4.0
28.91
28.16
mg/l
0.07
77
143
109
178
7.32
66.46
2.0
4.0
78.26
86.54
mg/l
0.05
78
143
108
175
7.36
66.32
2.0
3.9
1.16
2.10
ratio
0.44
16
15
311
1274
4.13
62.54
3.7
2.3
3.88
3.25
mg/l
3.20
278
1085
110
200
6.56
60.25
2.7
1.7
1.86
3.36
ug/l
0.46
98
174
168
452
4.84
59.33
4.1
2.6
76.54
72.31
e9/l
0.67
131
353
431
2281
4.53
58.63
10.1
4.3
33.27
35.40
g/l
11.73
408
2123
94
155
7.05
56.46
2.6
1.4
0.23
0.23
g/l
0.03
88
146
154
402
4.86
56.21
12.5
6.2
10.67
9.43
mmol/l
0.69
148
380
210
708
4.09
54.47
3.5
2.2
19.69
22.21
%
1.31
182
603
135
327
5.09
53.78
7.1
3.6
7.43
7.40
ph
1.31
25
40
245
929
3.85
53.43
2.4
1.6
2.63
2.48
g/l
0.22
185
539
60
61
10.86
53.36
2.2
2.1
0.75
0.98
g/l
0.34
44
51
68
82
9.27
53.34
2.2
2.3
—
—
—
0
0
214
742
4.00
53.16
3.5
2.2
2.25
2.33
g/l
1.17
200
681
223
798
3.93
52.88
6.9
3.2
0.80
0.81
mmol/l
0.81
209
739
84
133
7.22
52.28
2.0
4.5
—
—
—
0
0
334
1567
3.69
52.27
8.3
3.7
7.40
7.40
ph
0.15
110
292
195
648
4.04
51.22
1.8
1.3
811.03
488.38
titre
1.18
58
148
70
92
8.52
51.22
6.3
4.1
60.44
59.40
%
0.22
70
92
47
35
14.53
50.77
2.0
1.3
—
—
—
0
0
61
68
9.91
50.74
3.7
3.0
—
—
—
0
0
222
812
3.82
50.64
3.6
2.2
10.63
12.66
umol/l
3.08
209
743
68
89
8.53
49.89
6.0
3.6
4.36
4.61
e9/l
0.29
68
89
178
566
4.10
49.57
3.1
1.6
—
—
—
0
0
45
34
14.27
48.17
1.9
1.3
2.23
2.59
g/l
0.48
32
28
45
34
14.27
48.17
1.9
1.3
0.37
0.41
g/l
0.20
32
28
45
34
14.27
48.17
1.9
1.3
6.67
7.77
g/l
0.40
32
28
106
235
5.30
46.46
1.9
2.0
1.69
1.60
g/l
0.32
91
204
247
1027
3.46
45.34
4.8
2.9
489.02
527.79
mosm/kgh2o
2.37
221
881
75
128
6.59
43.25
1.4
1.8
—
—
—
0
0
66
99
7.40
42.94
1.7
1.7
4.19
4.77
mmol/24h
0.64
56
84
347
1819
3.28
42.48
4.2
3.4
2.33
2.36
mmol/l
3.26
307
1581
418
2454
3.56
42.18
27.7
15.2
1.32
1.26
inr
0.61
135
693
444
2709
3.79
42.05
14.0
5.9
11.37
11.11
umol/l
0.10
430
2561
330
1730
3.12
39.45
5.5
3.2
—
—
—
0
0
243
1073
3.19
39.26
1.5
1.3
0.82
1.48
u/ml
1.07
79
270
494
3338
4.37
37.76
10.1
4.7
2800.83
4368.02
e6/l
—
6
55
499
3417
4.44
36.88
10.9
4.5
—
—
—
0
0
539
3909
6.90
36.88
24.1
7.3
77.93
79.33
u/l
0.31
529
3636
237
1068
3.07
36.43
4.9
2.5
5.77
5.64
e6/l
0.05
224
966
356
2012
3.01
36.04
4.7
2.7
140.01
121.51
ug/l
0.64
336
1820
308
1611
2.96
35.97
4.0
2.3
55.10
60.98
u/l
0.86
289
1473
519
3708
5.04
34.84
15.2
4.3
18.65
13.21
mm/h
10.12
507
3393
79
174
5.10
34.51
3.0
3.2
0.34
0.18
g/l
0.72
30
60
49
67
7.90
34.43
3.1
2.7
—
—
—
0
0
291
1506
2.88
34.18
6.5
3.2
29.59
95.18
e6/l
0.83
252
1164
56
92
6.63
33.32
5.0
3.9
—
—
—
0
0
87
215
4.59
33.03
1.5
2.3
9.13
10.28
g/l
1.07
69
190
135
463
3.50
32.34
1.8
1.4
—
—
—
0
0
294
1574
2.77
31.69
3.5
2.1
101.46
207.44
u/l
5.11
276
1478
160
617
3.21
31.61
2.4
1.4
—
—
—
0
0
445
2959
3.22
31.59
12.3
4.5
6.38
6.69
mmol/l
3.64
435
2788
138
490
3.39
31.20
3.7
2.2
0.21
0.21
g/l
0.07
129
463
314
1748
2.75
31.18
7.7
3.8
66.11
107.14
e6/l
0.84
257
1266
271
1402
2.76
31.09
6.4
3.1
0.40
0.47
e6/l
0.28
236
1064
255
1283
2.77
30.84
4.4
2.6
5564.10
7556.15
umol/l
0.25
225
1087
52
86
6.55
30.70
1.4
1.3
—
—
—
0
0
126
431
3.46
30.15
1.8
1.4
—
—
—
0
0
92
254
4.12
30.12
8.3
3.4
—
—
—
0
0
141
523
3.25
29.55
2.0
1.6
—
—
—
0
0
42
59
7.60
28.77
1.9
1.7
62.93
65.21
%
0.13
34
42
219
1049
2.75
28.76
2.1
1.8
1234.41
1233.93
nmol/l
0.00
171
761
289
1590
2.64
28.68
4.6
2.3
—
—
—
0
0
45
69
6.99
28.50
1.2
1.1
—
—
—
0
0
144
552
3.14
28.45
10.6
4.0
—
—
—
0
0
294
1638
2.62
28.33
5.7
3.1
1717.54
1210.19
ng/l
1.77
263
1388
53
98
5.85
27.94
3.8
2.5
14.62
15.78
%
1.07
34
47
257
1357
2.61
27.47
6.4
3.0
—
—
—
0
0
72
182
4.38
26.39
1.6
2.2
35.21
37.20
g/l
1.74
54
158
91
279
3.69
25.51
1.5
1.3
—
—
—
0
0
232
1205
2.55
25.18
4.3
2.2
—
—
—
0
0
60
137
4.77
24.93
3.3
1.9
9.10
12.69
mg/l
2.24
53
127
241
1281
2.52
24.82
1.8
1.6
22.70
21.51
nmol/l
0.48
204
1062
39
60
6.90
24.58
3.3
3.5
—
—
—
0
0
42
70
6.39
24.54
1.3
1.3
16.49
10.87
u/l
0.71
33
55
358
2292
2.48
24.28
4.5
2.5
—
—
—
0
0
213
1093
2.51
23.39
2.7
1.7
1.71
1.17
mg/l
0.88
176
861
369
2419
2.46
23.38
7.2
4.1
0.00
0.00
estimate
0.50
127
480
50
104
5.17
23.14
6.4
3.9
2.77
2.63
mmol/l
0.12
38
71
370
2437
2.45
23.07
9.3
5.3
0.00
0.00
estimate
-0.00
122
448
138
575
2.84
23.04
10.1
6.1
11.13
12.34
kpa
1.31
132
554
138
575
2.84
23.04
10.1
6.1
5.14
5.10
kpa
0.18
131
553
372
2466
2.44
22.70
7.3
4.0
0.00
0.01
estimate
0.50
124
440
137
574
2.82
22.60
10.4
6.1
2.04
1.39
mmol/l
0.87
116
468
337
2143
2.38
22.57
32.0
9.9
0.00
0.00
e9/l
0.42
307
1760
46
91
5.41
22.51
4.0
2.5
—
—
—
0
0
47
99
5.08
21.43
1.6
1.3
68.86
66.48
mmol/l
0.10
36
82
59
151
4.24
21.18
1.4
1.2
5.67
2.55
u/ml
0.58
11
22
53
125
4.57
21.12
2.2
1.7
30559.54
20849.19
e6/l
0.28
41
84
166
790
2.55
21.08
3.7
1.8
30.26
29.30
s
1.15
158
760
59
154
4.15
20.63
1.4
1.2
22.81
3.17
u/ml
1.00
16
27
127
535
2.76
20.57
6.0
2.7
13.49
8.37
umol/l
0.76
114
471
317
2022
2.26
20.29
8.0
3.8
35.65
52.67
ng/l
0.49
273
1484
95
344
3.11
20.24
5.9
4.3
—
—
—
0
0
224
1242
2.31
20.06
9.6
3.6
91.91
90.91
%
0.23
219
1204
98
364
3.04
19.97
1.2
1.2
—
—
—
0
0
45
98
4.90
19.72
1.8
1.7
—
—
—
0
0
92
332
3.11
19.69
5.0
2.8
4.81
5.63
e9/l
0.39
65
257
107
423
2.88
19.47
15.5
6.5
—
—
—
0
0
224
1267
2.26
18.89
15.7
6.9
—
—
—
0
0
45
103
4.65
18.58
3.2
2.2
122.45
127.84
g/l
0.68
38
77
26
36
7.52
17.94
1.1
1.2
0.09
2.04
u/ml
0.91
17
20
26
36
7.52
17.94
2.1
1.4
26.89
31.76
%
0.26
20
25
135
624
2.52
17.92
14.0
6.0
102.86
104.03
mmol/l
1.78
135
624
36
70
5.42
17.91
1.4
1.3
—
—
—
0
0
39
83
4.97
17.54
1.7
1.5
—
—
—
0
0
113
486
2.65
17.36
8.9
4.0
2.85
2.12
mmol/l
1.27
95
410
162
828
2.33
17.12
1.5
1.3
24.78
11.82
u/ml
0.99
61
292
24
11
22.70
16.98
1.8
1.3
—
—
—
0
0
67
220
3.31
16.69
2.5
2.2
10.32
13.02
nmol/l
1.94
58
194
321
2165
2.09
16.56
2.4
2.1
95.10
94.99
pmol/l
0.01
173
1041
124
575
2.47
16.21
4.6
2.4
193.08
131.70
ug/g
1.38
104
453
111
493
2.55
15.88
9.1
3.9
5.84
5.85
kpa
0.02
106
476
254
1589
2.07
15.88
6.4
3.9
—
—
—
0
0
216
1275
2.11
15.75
6.9
3.6
—
—
—
0
0
163
868
2.22
15.41
1.4
1.3
64.55
39.42
iu/ml
0.66
61
278
407
3056
2.13
15.08
6.9
3.0
79.39
47.55
u/l
2.28
384
2798
290
1941
2.00
14.66
5.8
3.8
5.90
5.90
ph
—
10
130
34
75
4.75
14.65
1.2
1.3
296.28
306.17
u/ml
0.05
25
39
123
597
2.35
14.40
1.6
1.3
—
—
—
0
0
24
39
6.38
14.30
1.2
1.1
—
—
—
0
0
244
1550
2.00
14.21
8.2
2.9
30.93
31.17
u/l
0.05
233
1472
22
14
16.28
14.02
4.9
1.6
—
—
—
0
0
28
55
5.30
13.76
1.3
1.4
—
—
—
0
0
47
139
3.59
13.73
3.6
3.2
—
—
—
0
0
143
754
2.19
13.67
1.3
1.2
—
—
—
0
0
147
791
2.15
13.31
5.5
2.9
2.74
3.18
e6/l
0.26
98
418
92
405
2.51
13.29
7.6
4.1
—
—
—
0
0
39
104
3.95
13.20
1.2
1.4
—
—
—
0
0
550
4819
4.13
13.07
57.0
14.8
22.73
23.29
mg/l
0.18
534
3813
92
409
2.49
13.00
2.1
1.5
—
—
—
0
0
217
1358
1.96
12.91
8.7
4.4
0.00
0.00
estimate
-0.00
119
440
22
37
6.14
12.68
1.5
1.1
—
—
—
0
0
34
85
4.19
12.55
1.5
1.6
—
—
—
0
0
30
69
4.53
12.30
5.7
1.8
32.13
32.06
pg
0.03
30
69
32
79
4.23
12.00
6.2
1.8
—
—
—
0
0
39
113
3.63
11.74
1.5
1.2
46.00
86.25
titre
—
5
8
174
1040
1.96
11.62
3.5
3.0
2.47
2.46
mmol/l
0.53
157
916
27
60
4.67
11.53
1.3
1.1
5.44
3.83
u/ml
—
9
24
151
864
2.01
11.40
5.4
2.7
0.91
1.17
e6/l
0.75
102
485
69
285
2.61
11.32
2.3
2.9
4.03
4.39
pmol/l
2.04
56
245
26
57
4.73
11.29
1.2
1.2
—
—
—
0
0
41
127
3.40
11.17
1.5
1.3
—
555.00
—
0
6
285
2021
1.81
10.98
2.7
2.1
—
—
—
0
0
24
52
4.77
10.56
2.1
2.4
1.27
1.57
g/24h
0.20
14
27
23
31
7.68
10.27
1.3
1.6
—
—
—
0
0
91
449
2.22
10.04
3.9
2.3
36.34
30.77
u/l
0.59
82
369
65
277
2.52
9.98
1.5
1.3
—
—
—
0
0
232
1583
1.78
9.89
4.0
3.1
5.86
6.83
mmol/l
2.95
204
1303
36
111
3.39
9.88
1.2
1.2
—
—
—
0
0
21
43
5.03
9.86
1.8
1.5
161828.50
352990.82
e6/l
0.30
16
28
56
229
2.60
9.36
1.5
1.2
—
—
—
0
0
54
217
2.64
9.34
1.9
1.9
—
—
—
0
0
25
62
4.17
9.33
1.3
1.4
269.67
276.78
mosm/kgh2o
0.78
18
41
179
1147
1.81
9.32
1.8
1.7
481.73
458.85
pmol/l
0.49
154
924
32
96
3.47
9.17
1.9
1.6
—
—
—
0
0
91
468
2.12
9.01
2.1
1.4
—
—
—
0
0
20
43
4.78
8.88
1.4
1.2
—
—
—
0
0
21
32
6.77
8.73
1.3
1.3
233.33
128.00
titre
—
9
5
43
159
2.84
8.71
1.8
1.4
290.81
292.90
ug/g
0.03
32
95
155
969
1.82
8.66
7.4
4.1
636.92
309.07
ng/l
0.30
134
778
456
3859
1.87
8.51
5.2
4.1
15.31
14.97
pmol/l
1.96
420
3457
90
474
2.07
8.35
2.9
2.4
8.89
6.15
ug/l
0.44
77
408
82
417
2.13
8.34
9.9
3.5
4.92
4.42
kpa
1.21
77
400
22
54
4.20
8.33
1.5
1.2
25.75
31.99
g/l
1.11
22
47
20
31
6.64
8.25
1.4
1.2
—
—
—
0
0
56
247
2.40
7.98
16.1
7.4
—
—
—
0
0
20
33
6.24
7.91
3.7
1.4
0.87
1.02
g/l
1.04
20
33
20
33
6.24
7.91
2.7
2.4
—
—
—
0
0
22
57
3.97
7.77
1.4
1.3
—
—
—
0
0
15
17
9.03
7.58
1.1
1.1
—
—
—
0
0
77
398
2.08
7.49
1.8
1.4
—
—
—
0
0
13
12
11.05
7.32
2.2
2.4
190.00
290.00
e6/l
—
8
5
19
46
4.24
7.32
2.6
1.1
—
—
—
0
0
28
90
3.22
7.23
1.5
1.3
—
—
—
0
0
17
26
6.70
7.16
1.4
1.3
—
—
—
0
0
509
4550
2.02
6.92
6.4
5.0
1.86
2.23
mu/l
0.74
474
4095
11
8
13.99
6.91
1.0
1.0
—
—
—
0
0
23
67
3.53
6.91
1.1
1.0
—
—
—
0
0
21
59
3.66
6.65
1.4
2.4
—
—
—
0
0
36
142
2.64
6.49
7.6
6.3
1.25
1.25
mmol/l
0.01
31
128
15
24
6.39
6.20
1.9
1.6
—
—
—
0
0
18
48
3.84
6.13
1.4
1.5
—
—
—
0
0
546
5056
2.53
6.12
54.6
17.3
138.77
139.69
mmol/l
9.79
539
4914
12
14
8.73
6.08
2.1
1.1
1.52
2.16
mmol/l
0.13
12
14
546
5066
2.49
5.91
54.9
17.5
3.95
3.98
mmol/l
1.41
539
4919
16
41
3.99
5.75
1.4
1.2
8260.00
61710.59
e6/l
—
10
22
34
140
2.52
5.64
2.9
3.2
0.93
0.88
nmol/l
0.16
27
108
14
24
5.95
5.56
2.4
1.5
—
—
—
0
0
10
10
10.15
5.55
1.0
1.1
—
—
—
0
0
96
591
1.75
5.47
3.2
3.9
4.55
17.51
ug/l
1.11
81
491
22
73
3.09
5.43
1.1
1.1
—
—
—
0
0
9
8
11.40
5.30
1.0
1.4
—
—
—
0
0
10
11
9.23
5.30
1.8
1.6
—
—
—
0
0
21
69
3.12
5.27
1.5
1.1
—
—
—
0
0
45
220
2.13
5.08
2.5
2.9
568.09
937.70
u/ml
0.20
33
190
18
55
3.35
5.06
1.1
1.1
1.71
1.50
g/l
1.40
18
48
536
4984
2.09
4.95
44.8
14.1
—
—
—
0
0
11
17
6.57
4.79
1.8
1.2
—
—
—
0
0
549
5161
2.36
4.78
32.2
10.8
25.81
24.44
u/l
0.81
542
4950
44
220
2.08
4.70
10.2
4.3
—
—
—
0
0
16
48
3.40
4.63
5.3
2.8
—
—
—
0
0
14
31
4.60
4.58
1.4
1.1
1.91
1.90
mmol/l
0.00
14
31
9
11
8.29
4.57
1.4
2.7
—
—
—
0
0
16
49
3.33
4.50
1.1
1.1
—
—
—
0
0
52
281
1.93
4.49
2.3
2.4
—
—
—
0
0
15
37
4.13
4.43
1.7
1.1
—
—
—
0
0
28
120
2.40
4.32
14.4
4.5
—
—
—
0
0
8
9
8.99
4.29
2.0
1.4
—
—
—
0
0
7
6
11.79
4.28
1.1
1.2
—
—
—
0
0
26
109
2.45
4.20
1.8
1.6
3.44
5.86
iu/l
—
8
34
9
13
7.01
4.17
1.6
1.2
—
—
—
0
0
7
7
10.10
4.02
2.1
1.4
44.00
42.71
umol/l
—
7
7
14
43
3.31
3.93
1.2
1.2
—
—
—
0
0
14
37
3.85
3.91
3.5
2.5
—
—
—
0
0
14
37
3.85
3.91
1.5
1.2
—
—
—
0
0
8
11
7.36
3.87
1.0
1.1
—
—
—
0
0
25
108
2.37
3.81
3.9
3.7
182.55
3281.35
u/ml
0.74
20
103
11
24
4.65
3.76
5.5
15.3
—
—
—
0
0
8
12
6.74
3.68
1.1
1.4
—
—
—
0
0
10
21
4.83
3.57
1.0
1.1
713.80
110.64
iu/ml
—
10
21
7
9
7.86
3.56
1.1
1.1
—
—
—
0
0
26
118
2.26
3.56
1.5
1.3
36.98
28.31
iu/l
0.41
20
98
91
618
1.56
3.51
1.3
1.3
—
—
—
0
0
6
6
10.09
3.50
2.0
1.5
116.17
91.83
ng/l
—
6
6
7
226
0.30
3.38
1.3
1.4
—
—
—
0
0
9
18
5.06
3.38
5.3
3.9
54.44
51.83
%
—
9
18
15
53
2.88
3.38
1.5
1.3
378.80
284.04
pmol/l
—
10
48
8
14
5.78
3.35
1.3
1.0
—
—
—
0
0
8
14
5.78
3.35
1.3
1.0
—
—
—
0
0
8
14
5.78
3.35
1.3
1.0
—
—
—
0
0
11
28
3.98
3.30
1.2
1.9
—
—
—
0
0
70
455
1.61
3.25
6.8
3.5
—
—
—
0
0
10
24
4.22
3.20
1.0
1.1
—
—
—
0
0
8
15
5.39
3.20
2.3
1.8
—
—
—
0
0
11
29
3.85
3.20
2.7
1.4
90.27
76.97
umol/l
0.31
11
29
553
5299
2.09
3.13
73.2
22.2
7.71
6.64
e9/l
17.54
544
5123
16
62
2.63
3.07
3.4
4.9
280.45
385.07
umol/l
1.62
11
57
21
93
2.31
3.07
2.5
1.3
—
—
—
0
0
13
45
2.93
3.04
2.3
1.4
—
—
—
0
0
21
94
2.28
3.00
18.6
4.5
63.73
59.98
%
0.32
21
94
5
5
10.07
2.98
1.4
1.4
—
—
—
0
0
552
5296
2.02
2.95
73.8
22.2
37.54
39.71
%
11.81
514
4919
552
5299
2.00
2.89
72.8
22.2
92.80
91.33
fl
8.88
546
5203
552
5299
2.00
2.89
72.7
22.1
30.30
30.30
pg
0.01
546
5202
552
5299
2.00
2.89
73.3
22.2
260.86
250.42
e9/l
2.39
545
5144
552
5300
2.00
2.87
73.8
22.3
124.25
133.24
g/l
35.90
547
5200
552
5300
2.00
2.87
73.2
22.2
4.14
4.43
e12/l
29.01
545
5126
6
9
6.72
2.87
1.2
2.6
—
—
—
0
0
6
9
6.72
2.87
1.2
2.6
—
—
—
0
0
8
18
4.49
2.80
1.1
1.1
—
—
—
0
0
8
18
4.49
2.80
1.1
1.1
—
—
—
0
0
7
14
5.05
2.73
1.0
1.1
—
—
—
0
0
25
126
2.03
2.69
2.3
1.3
1529.96
518.03
mg/l
0.49
25
119
7
15
4.71
2.60
2.4
2.7
37630.86
39460.33
ug/l
—
7
15
10
31
3.26
2.53
6.2
2.9
—
—
—
0
0
490
4599
1.44
2.50
6.7
6.1
39.43
40.12
mmol/mol
0.97
443
4210
51
329
1.60
2.48
6.4
2.9
—
—
—
0
0
6
176
0.33
2.44
1.0
1.1
—
—
—
0
0
9
27
3.37
2.40
1.7
1.4
—
—
—
0
0
21
104
2.06
2.39
10.1
6.5
105.05
104.99
mmol/l
0.02
21
96
21
104
2.06
2.39
10.1
6.5
10.29
10.97
mmol/l
0.68
21
96
13
53
2.49
2.29
1.7
1.2
—
—
—
0
0
147
1179
1.33
2.28
7.4
4.0
—
—
—
0
0
0
62
0.00
2.23
0.0
1.5
—
—
—
0
0
9
29
3.14
2.23
1.0
1.0
321.22
297.33
mg/l
—
9
24
32
188
1.74
2.22
2.4
2.7
—
—
—
0
0
184
1540
1.29
2.07
3.9
3.2
594.68
345.44
mg/l
0.30
125
929
6
15
4.03
2.04
1.0
1.3
57.67
72.07
nmol/24h
—
6
15
192
1619
1.28
2.03
4.5
3.8
28.85
6.65
mg/mmol
1.94
120
970
16
309
0.50
2.01
1.3
1.4
—
—
—
0
0
5
11
4.57
1.94
1.2
1.7
—
—
—
0
0
6
16
3.78
1.94
1.3
1.2
—
—
—
0
0
5
12
4.19
1.82
1.2
1.1
—
—
—
0
0
129
1562
0.78
1.78
3.0
3.0
—
—
—
0
0
6
19
3.18
1.66
1.0
1.1
1281.83
1653.53
miu/ml
—
6
19
6
19
3.18
1.66
2.7
2.1
56.83
48.23
umol/l
—
6
13
8
31
2.60
1.66
1.3
1.6
—
—
—
0
0
9
189
0.47
1.64
1.2
1.7
—
—
—
0
0
10
42
2.40
1.62
1.9
7.9
11.39
10.53
%
—
10
42
5
14
3.59
1.62
2.6
1.5
—
—
—
0
0
5
14
3.59
1.62
1.2
1.1
—
—
—
0
0
14
71
2.00
1.55
2.6
2.5
—
—
—
0
0
5
15
3.35
1.52
1.2
1.2
—
—
—
0
0
44
312
1.44
1.46
1.2
1.2
27.27
136.36
iu/ml
6.77
15
124
19
110
1.75
1.44
7.7
3.9
33.09
29.71
mg/l
0.20
11
63
138
1163
1.25
1.43
1.4
1.3
—
—
—
0
0
378
3528
1.21
1.36
5.8
4.1
—
—
—
0
0
0
37
0.00
1.35
0.0
1.0
—
278.81
—
0
21
11
54
2.06
1.33
1.1
1.1
—
—
—
0
0
26
169
1.56
1.31
1.3
1.2
—
—
—
0
0
9
43
2.11
1.30
1.2
1.3
—
—
—
0
0
8
34
2.37
1.29
2.0
1.2
9.52
6.06
ug/l
—
8
29
29
194
1.52
1.29
1.6
1.5
—
—
—
0
0
5
18
2.79
1.28
1.0
1.6
68.60
92.00
umol/l
—
5
11
5
18
2.79
1.28
4.4
2.7
—
—
—
0
0
14
77
1.84
1.26
1.3
1.2
—
—
—
0
0
6
25
2.41
1.24
1.3
1.5
125.50
176.79
mmol/24h
—
6
25
498
4800
1.28
1.21
5.1
4.9
5.60
5.98
mmol/l
11.71
449
4325
14
79
1.79
1.18
1.3
1.2
—
—
—
0
0
14
79
1.79
1.18
1.3
1.2
—
—
—
0
0
10
50
2.02
1.17
1.4
1.1
—
—
—
0
0
10
50
2.02
1.17
1.2
2.6
—
—
—
0
0
10
51
1.98
1.11
1.4
1.2
—
—
—
0
0
23
152
1.53
1.10
1.2
1.1
—
—
—
0
0
25
169
1.50
1.09
1.3
1.5
—
—
—
0
0
9
50
1.81
0.97
1.4
1.1
—
—
—
0
0
34
453
0.73
0.96
1.5
1.5
—
—
—
0
0
13
77
1.70
0.96
1.4
1.2
—
—
—
0
0
9
51
1.78
0.95
3.9
1.5
—
—
—
0
0
9
51
1.78
0.95
1.2
1.3
—
—
—
0
0
10
163
0.61
0.79
1.3
1.3
—
—
—
0
0
6
33
1.83
0.79
7.3
1.8
—
—
—
0
0
6
34
1.77
0.76
1.0
1.1
—
—
—
0
0
123
1102
1.15
0.66
9.0
4.5
1.01
1.02
kg/l
1.43
30
145
10
62
1.62
0.65
1.1
1.2
—
—
—
0
0
5
29
1.73
0.64
1.8
1.7
—
—
—
0
0
492
4807
1.16
0.60
4.9
4.7
4.67
4.70
mmol/l
0.30
440
4378
488
4773
1.15
0.55
4.8
4.7
1.59
1.53
mmol/l
1.99
436
4322
11
74
1.50
0.53
1.2
1.1
—
—
—
0
0
11
74
1.50
0.53
1.3
1.2
—
—
—
0
0
470
4603
1.11
0.44
4.5
4.2
1.35
1.27
mmol/l
1.64
412
4135
114
1048
1.11
0.43
5.3
5.2
2.24
2.50
ug/l
0.15
98
932
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
499
4925
1.10
0.30
5.2
5.3
2.61
2.74
mmol/l
2.60
449
4466
8
66
1.22
0.27
1.0
1.2
0.70
0.62
nmol/l
—
8
60
17
141
1.21
0.26
5.6
4.8
—
—
—
0
0
11
137
0.80
0.24
1.5
1.1
—
—
—
0
0
5
38
1.32
0.23
2.6
2.2
2.62
2.31
ug/l
—
5
32
20
172
1.17
0.22
21.8
11.0
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
—
—
—
0
0
28
257
1.09
0.13
4.6
3.7
—
—
—
0
0
58
611
0.94
0.13
2.6
3.0
0.49
0.76
ug/l
3.42
41
400
35
326
1.08
0.12
1.1
1.3
—
—
—
0
0
139
1365
1.02
0.07
1.5
1.6
1.50
1.36
mmol/l
0.83
125
1136
12
125
0.96
0.00
2.4
2.4
325.80
89.65
ug/min
—
5
68
13
128
1.02
0.00
4.0
2.7
—
—
—
0
0
10
101
0.99
0.00
1.5
1.4
0.97
0.88
nmol/l
—
10
82
30
299
1.00
0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
1.73
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
65
0.92
-0.00
1.7
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint OSTPOPATFRACTURE and mortality.

Females

Parameter HR [95% CI] p-value
OSTPOPATFRACTURE 2.879 [2.39, 3.46] < 0.001
Birth year 0.996 [0.99, 1.01] 0.421

During the follow-up period (1.1.1998 — 31.12.2019), 572 out of 1455 females with OSTPOPATFRACTURE died.

Males

Parameter HR [95% CI] p-value
OSTPOPATFRACTURE 4.177 [3.06, 5.7] < 0.001
Birth year 0.991 [0.98, 1.0] 0.09

During the follow-up period (1.1.1998 — 31.12.2019), 329 out of 649 males with OSTPOPATFRACTURE died.

Mortality risk

Mortality risk for people of age

years, who have OSTPOPATFRACTURE.

N-year risk Females Males
1 0.297% 0.753%
5 1.672% 4.626%
10 3.99% 12.785%
15 7.552% 23.481%
20 14.115% 37.703%

Relationships between endpoints

Index endpoint: OSTPOPATFRACTURE – Drug-induced osteoporosis with pathological fracture

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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