≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback
info icon

This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Traumatic amputation of lower leg

Endpoint Browser

ST19_TRAUMAT_AMPUT_LOWER_LEG

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — S88
  • Cause of death: ICD-10 — S88

2 out of 7 registries used, show all original rules.

77

4. Check minimum number of events

None

77

5. Include endpoints

None

77

6. Filter based on genotype QC (FinnGen only)

75

Control definitions (FinnGen only)

Control exclude
ST19_INJURI_KNEE_LOWER_LEG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S8
Name in latin
Amputatio traumatica genus sive cruris

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 75 13 62
Unadjusted period prevalence (%) 0.02 0.00 0.03
Median age at first event (years) 53.06 52.19 53.24

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
77
Matched controls
770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S88.1
ICD-10 Finland
Traumatic amputation at level between knee and ankle
+∞
66.6
54
*
NGQ20
NOMESCO Finland
Amputation of lower leg
148.6
34.1
34
*
X59
ICD-10 Finland
Exposure to unspecified factor
12.5
28.7
43
71
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
53.2
25.8
30
9
NGQ48
NOMESCO Finland
Revision of exarticulation or amputation stump of knee or lower leg
+∞
24.2
22
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
22.7
21.0
31
22
ZXD05
NOMESCO Finland
Urgent procedure
8.4
19.8
50
139
N03AX16
ATC
[U] pregabalin
7.3
17.4
40
99
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
+∞
17.3
16
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
8.2
16.5
28
50
S88.0
ICD-10 Finland
Traumatic amputation at knee level
+∞
16.2
15
*
ZZA00
NOMESCO Finland
Split skin graft
31.4
16.2
21
9
Z89.5
ICD-10 Finland
Acquired absence of leg at or below knee
+∞
15.1
14
*
S88.9
ICD-10 Finland
Traumatic amputation of lower leg, level unspecified
+∞
15.1
14
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
6.3
12.7
28
64
SPAT1148
SPAT
Treatment of chronic ulcer or burn
6.5
12.5
26
56
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.7
12.5
33
89
T93.6
ICD-10 Finland
Sequelae of crushing injury and traumatic amputation of lower limb
+∞
11.8
11
*
L28
ICPC
Limited function/disability (L)
5.9
11.4
26
61
NFQ20
NOMESCO Finland
Amputation of femur
51.4
11.3
13
*
A10AE04
ATC
insulin glargine; parenteral
6.4
11.1
22
45
NHQ40
NOMESCO Finland
Amputation of toe
19.8
10.9
16
10
T87.4
ICD-10 Finland
Infection of amputation stump
126.5
10.7
11
*
SPAT1229
SPAT
Assessment of need for aid
10.8
10.4
20
24
WX306
NOMESCO Finland
Lumbar epidural anesthesy
24.0
10.2
14
7
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
14.2
10.2
17
15
ZXA05
NOMESCO Finland
Left side
4.9
10.2
32
98
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
6.3
9.7
19
38
J01FF01
ATC
clindamycin; systemic
4.5
9.6
38
138
S87.8
ICD-10 Finland
Crushing injury of other and unspecified parts of lower leg
+∞
9.6
9
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
11.1
9.1
17
19
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.7
9.0
28
84
A46
ICD-10 Finland
Erysipelas
4.7
9.0
27
79
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
56.7
8.9
10
*
NG4AA
NOMESCO Finland
Lower leg X-ray examination
23.3
8.8
12
6
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.5
8.8
20
46
L89
ICD-10 Finland
Decubitus ulcer and pressure area
20.0
8.4
12
7
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
8.4
8.2
18
27
AA1AD
NOMESCO Finland
CT of head and brain
4.0
8.1
35
133
H3603, E103,
ICD-10 Finland
50.3
7.9
9
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.4
7.8
17
25
ZXE20
NOMESCO Finland
More than three and less than five hours
4.6
7.7
22
61
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
15.5
7.7
12
9
WX702
NOMESCO Finland
Supraglottic ventilation device
12.7
7.6
13
12
CKC12
NOMESCO Finland
Photocoagulation of retina
10.4
7.4
14
16
G54.6
ICD-10 Finland
Phantom limb syndrome with pain
+∞
7.4
7
*
S82.8
ICD-10 Finland
Fractures of other parts of lower leg
+∞
7.4
7
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.5
7.2
21
59
WX320
NOMESCO Finland
Spinalanesthesy
4.0
7.1
26
87
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
44.1
6.9
8
*
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
44.1
6.9
8
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
8.7
6.8
14
19
WX408
NOMESCO Finland
General anesthesy, balanced
3.6
6.6
31
122
WX400
NOMESCO Finland
Inhalation anesthesy
10.7
6.6
12
13
X58
ICD-10 Finland
Exposure to other specified factors
4.6
6.5
18
48
ZX198
NOMESCO Finland
Other local administration
29.3
6.4
8
*
S78.1
ICD-10 Finland
Traumatic amputation at level between hip and knee
+∞
6.3
6
*
S82.2
ICD-10 Finland
Fracture of shaft of tibia
+∞
6.3
6
*
A28
ICPC
Limited function/disability NOS
4.1
6.3
21
65

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
32
90
5.37
11.43
4.2
1.9
—
—
—
0
0
26
72
4.94
9.25
3.6
1.8
—
—
—
0
0
36
181
2.86
4.80
6.5
4.8
—
—
—
0
0
44
276
2.39
3.42
8.5
6.3
2.86
2.77
%
0.09
39
263
44
278
2.36
3.34
8.5
6.3
60.43
58.73
%
0.43
39
267
44
278
2.36
3.34
9.2
6.6
7.76
8.64
%
0.91
39
267
33
184
2.39
3.33
3.6
2.4
—
—
—
0
0
16
66
2.80
2.94
2.1
1.5
—
—
—
0
0
41
264
2.18
2.83
14.0
6.1
1.21
1.21
mmol/l
0.02
35
243
43
283
2.18
2.80
9.3
6.4
23.66
25.90
%
0.67
38
271
24
125
2.34
2.75
3.4
3.4
—
—
—
0
0
19
93
2.38
2.48
2.5
1.8
—
—
—
0
0
43
293
2.06
2.46
24.2
12.0
1.44
1.30
inr
—
9
76
42
284
2.05
2.45
22.4
8.0
1.21
1.21
mmol/l
0.30
36
251
20
101
2.32
2.43
2.1
1.8
29.76
29.25
s
0.17
20
96
5
9
5.85
2.25
4.2
1.6
—
—
—
0
0
23
128
2.14
2.21
4.9
3.5
1.02
1.02
kg/l
—
6
14
44
313
1.95
2.12
9.7
6.3
1.77
1.77
e9/l
0.02
39
280
52
393
2.00
2.09
5.6
4.1
—
—
—
0
0
6
15
4.24
2.08
1.0
1.1
—
—
—
0
0
44
316
1.92
2.04
12.4
6.6
0.22
0.19
e9/l
0.42
39
282
53
630
0.49
2.03
5.3
4.6
1.26
1.35
mmol/l
1.07
46
569
5
11
4.78
1.97
1.4
1.8
294.00
207.67
ug/g
—
5
6
8
28
3.07
1.92
1.0
1.3
—
—
—
0
0
42
306
1.82
1.78
9.9
6.2
0.04
0.04
e9/l
0.07
36
271
14
245
0.48
1.72
3.1
2.9
—
—
—
0
0
8
32
2.67
1.65
27.5
6.1
—
—
—
0
0
15
80
2.09
1.58
2.3
1.5
—
—
—
0
0
28
186
1.79
1.57
4.2
3.1
24.27
355.82
e6/l
0.50
23
150
28
186
1.79
1.57
8.5
3.8
2.28
2.33
mmol/l
0.72
20
168
41
305
1.74
1.56
10.1
6.3
0.68
0.60
e9/l
1.53
36
269
53
616
0.55
1.50
4.3
4.2
1.62
1.38
mmol/l
1.23
47
552
30
207
1.74
1.47
4.4
3.5
15.23
24.87
e6/l
0.59
23
160
5
16
3.27
1.46
5.8
1.4
—
—
—
0
0
25
164
1.78
1.45
4.0
3.0
—
—
—
0
0
55
629
0.56
1.37
5.0
4.7
4.57
4.54
mmol/l
0.08
47
571
15
85
1.95
1.35
2.1
1.4
—
—
—
0
0
11
57
2.08
1.24
11.4
4.3
—
—
—
0
0
5
19
2.74
1.23
4.2
1.2
—
—
—
0
0
5
19
2.74
1.23
1.0
1.2
—
—
—
0
0
57
639
0.58
1.15
5.4
5.2
2.73
2.73
mmol/l
0.01
50
581
37
285
1.57
1.12
4.7
3.5
0.00
0.02
estimate
—
7
65
23
158
1.65
1.11
12.2
7.5
—
—
—
0
0
5
21
2.47
1.11
4.4
1.3
—
—
—
0
0
5
21
2.47
1.11
4.4
1.3
—
—
—
0
0
5
21
2.47
1.11
4.2
1.2
—
—
—
0
0
5
21
2.47
1.11
4.4
1.3
—
—
—
0
0
5
21
2.47
1.11
4.6
1.3
—
—
—
0
0
5
21
2.47
1.11
2.4
1.9
—
—
—
0
0
37
286
1.57
1.10
10.4
6.6
—
—
—
0
0
37
290
1.53
1.02
4.7
3.5
0.00
0.00
estimate
—
6
56
19
127
1.66
1.01
4.2
3.1
548.50
568.07
mosm/kgh2o
0.17
14
111
7
36
2.04
1.00
2.9
2.4
—
—
—
0
0
18
119
1.67
0.99
1.7
1.5
1111.64
1213.55
nmol/l
0.24
11
91
14
88
1.72
0.92
6.1
2.2
18.50
23.87
%
—
8
82
67
607
1.80
0.92
40.3
15.1
29.77
23.89
mg/l
0.90
61
496
18
122
1.62
0.90
1.9
1.9
0.94
1.82
mg/l
1.32
13
104
9
53
1.79
0.79
2.1
2.4
277.00
142.85
ug/g
—
9
43
5
24
2.16
0.76
1.8
2.3
9.00
144.89
u/ml
—
5
19
35
285
1.42
0.74
6.9
4.7
0.00
0.00
estimate
—
6
60
7
41
1.78
0.72
1.0
3.0
—
—
—
0
0
7
41
1.78
0.72
15.9
2.9
114.86
128.85
g/l
—
7
41
8
54
1.54
0.59
2.0
1.5
—
—
—
0
0
56
608
0.71
0.58
6.0
4.7
6.65
6.10
mmol/l
1.26
50
556
5
80
0.60
0.49
1.8
1.3
—
—
—
0
0
8
55
1.51
0.45
7.6
3.3
—
—
—
0
0
8
58
1.42
0.43
1.0
1.4
—
—
—
0
0
5
32
1.60
0.43
6.2
5.1
—
—
—
0
0
25
210
1.28
0.40
4.0
4.0
79.30
10.52
mg/mmol
0.89
16
135
9
68
1.37
0.39
2.7
1.3
—
—
—
0
0
12
90
1.39
0.38
16.4
6.0
105.08
104.21
mmol/l
0.15
12
90
6
85
0.68
0.35
3.2
2.2
9.83
14.26
nmol/l
—
6
78
23
195
1.26
0.33
3.7
3.6
394.63
74.06
mg/l
1.04
14
133
16
130
1.29
0.32
4.6
3.5
—
—
—
0
0
7
55
1.30
0.31
2.6
5.2
—
—
—
0
0
26
229
1.20
0.26
1.9
1.9
90.24
90.90
pmol/l
0.04
13
118
47
437
1.19
0.26
4.1
4.2
—
—
—
0
0
19
220
0.82
0.26
4.4
2.0
—
—
—
0
0
5
38
1.34
0.24
1.2
1.3
—
—
—
0
0
24
212
1.19
0.23
4.2
3.2
7.01
8.52
mmol/l
0.82
19
173
19
164
1.21
0.23
5.2
3.4
0.00
0.02
estimate
—
6
54
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.1
—
65.03
—
0
13
45
423
1.15
0.19
2.8
3.3
14.71
14.97
pmol/l
0.31
40
381
17
148
1.19
0.19
1.3
1.3
—
—
—
0
0
18
162
1.15
0.13
5.2
3.2
—
—
—
0
0
67
655
1.18
0.11
31.4
13.4
—
—
—
0
0
16
175
0.89
0.09
5.6
4.4
—
—
—
0
0
6
55
1.10
0.09
31.3
7.4
—
—
—
0
0
52
534
0.92
0.07
51.5
17.7
16.85
15.22
%
0.72
52
524
10
109
0.91
0.04
1.3
1.3
—
0.82
—
0
31
67
668
1.02
0.00
36.2
17.4
101.34
83.65
umol/l
0.69
67
668
29
287
1.02
0.00
15.4
10.1
0.00
0.01
e9/l
0.50
24
239
59
594
0.97
0.00
8.5
6.1
45.72
40.74
mmol/mol
1.95
54
555
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
13.15
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
5.90
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
69
691
0.99
-0.00
50.0
21.4
38.93
41.09
%
1.52
59
659
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
11.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
13.79
—
0
7
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
1.26
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
1.62
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
1.04
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.6
—
4.80
—
0
9
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.6
—
57.89
—
0
9

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_TRAUMAT_AMPUT_LOWER_LEG – Traumatic amputation of lower leg

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).