Bilateral cryptorchidism (undescended testicles)

Q17_BILATERAL_CRYPTORCHIDISM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 Q53.2
  • Cause of death: ICD-10 Q53.2

2 out of 7 registries used, show all original rules.

79

4. Check minimum number of events

None

79

5. Include endpoints

None

79

6. Filter based on genotype QC (FinnGen only)

69

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 69 - 69
Unadjusted period prevalence (%) 0.03 - 0.03
Median age at first event (years) 4.32 - 4.32

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
79
Matched controls
790
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
+∞
113.6
79
*
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
170.0
49.3
48
7
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
44.5
22.4
27
9
KFH10
NOMESCO Finland
Orchiopexy
70.3
19.0
21
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
8.5
15.8
25
41
ZXA10
NOMESCO Finland
Bilateral
6.4
14.9
36
91
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
14.1
14.3
25
25
R62.0
ICD-10 Finland
Delayed milestone
8.1
13.8
22
36
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
17.5
11.7
18
13
F83
ICD-10 Finland
Mixed specific developmental disorders
7.1
11.4
20
36
ZXE10
NOMESCO Finland
More than one and less than three hours
4.9
11.3
47
181
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.4
10.7
21
42
JAH01
NOMESCO Finland
Laparoscopy
27.9
10.7
14
6
H01AC01
ATC
somatropin; parenteral
6.5
10.5
20
39
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
5.3
10.3
27
71
Z01.1
ICD-10 Finland
Examination of ears and hearing
4.5
9.6
35
119
WX408
NOMESCO Finland
General anesthesy, balanced
4.3
9.6
46
192
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
13.0
9.3
16
15
ZXA05
NOMESCO Finland
Left side
4.9
9.0
25
68
ZXD20
NOMESCO Finland
Day surgery
5.5
8.7
20
46
Z3229
NOMESCO Finland
Other healthcare associate professional
4.8
8.7
25
70
F82
ICD-10 Finland
Specific developmental disorder of motor function
8.6
8.4
18
26
Z31.5
ICD-10 Finland
Genetic counselling
5.2
8.3
20
48
TPH04
NOMESCO Finland
Cathetrisation of vein
4.4
8.2
27
84
602
Kela drug reimbursment
Children's severe malnutrition
8.7
8.0
17
24
ZXD10
NOMESCO Finland
Scheduled procedure
3.9
8.0
49
234
ZXE20
NOMESCO Finland
More than three and less than five hours
4.5
7.9
24
70
XF400
NOMESCO Finland
ECG with 12 standard connections
4.0
7.8
32
116
121
Kela drug reimbursment
Severe hypofunction of sexual glands
88.0
7.6
8
*
E29.1
ICD-10 Finland
Testicular hypofunction
33.4
7.3
9
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.7
7.2
14
17
FM2CE, ,
NOMESCO Finland
4.7
7.0
19
50
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
6.7
29
108
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
9.5
6.6
13
16
7525A
ICD-9 Finland
Congenital anomalies of genital organs, Undescended testicle[RETENTIO TESTIS (CRYPTORCHISMUS)]
75.7
6.5
7
*
Q53.9
ICD-10 Finland
Undescended testicle, unspecified
75.7
6.5
7
*
XA800
NOMESCO Finland
Neuropsychological investigation
4.0
6.5
22
69
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
29.3
6.4
8
*
P85
ICPC
Mental retardation
9.9
6.3
12
14
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
6.4
6.3
16
30
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.5
6.3
28
106
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.6
6.1
16
41
101
Kela drug reimbursment
Anterior pituitary hypofunction
7.2
6.0
14
23

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
57
6.31
12.25
3.4
2.2
6.91
3.59
u/l
0.91
18
39
22
45
6.39
11.03
3.5
2.3
11.17
5.42
iu/l
0.75
16
28
22
83
3.29
4.82
24.7
26.1
1.23
1.10
mg/l
0.64
22
83
30
145
2.72
4.20
3.3
4.2
—
—
—
0
0
29
140
2.69
4.05
3.9
4.0
2.42
2.41
mmol/l
0.15
29
130
8
16
5.43
3.14
3.4
15.3
—
—
—
0
0
12
43
3.11
2.79
1.7
1.6
—
—
—
0
0
28
158
2.20
2.64
17.4
8.1
—
—
—
0
0
55
403
2.20
2.63
4.6
3.0
14.86
14.62
pmol/l
0.32
55
379
18
84
2.48
2.59
2.6
6.3
1.48
2.07
mg/l
0.21
11
63
29
168
2.15
2.55
12.7
10.7
23.86
23.49
mmol/l
0.36
29
168
71
596
2.89
2.51
14.4
9.4
—
—
—
0
0
5
8
6.58
2.40
1.6
2.9
1.26
1.02
umol/l
—
5
8
5
8
6.58
2.40
2.8
3.6
—
—
—
0
0
14
60
2.62
2.38
3.9
3.7
—
—
—
0
0
71
602
2.77
2.35
18.5
12.8
63.23
64.60
umol/l
0.14
71
602
8
23
3.75
2.34
6.5
6.6
2.29
3.06
ug/l
—
8
23
29
173
2.07
2.33
8.1
9.2
78.03
82.86
%
0.51
29
173
10
36
3.03
2.23
2.1
2.1
—
—
—
0
0
31
198
1.93
2.02
5.6
4.3
91.41
103.32
ug/l
0.19
31
188
5
11
4.77
1.97
2.4
3.3
14.72
11.72
umol/l
—
5
11
14
66
2.36
1.96
9.9
2.3
—
—
—
0
0
11
47
2.56
1.87
3.7
9.0
21.27
23.30
s
0.89
11
47
7
25
2.97
1.69
4.9
1.6
191.43
241.68
pmol/l
—
7
25
45
338
1.77
1.67
7.9
8.6
6.19
6.34
mmol/l
0.15
45
328
36
254
1.77
1.65
11.6
12.4
—
—
—
0
0
5
14
3.74
1.64
4.2
3.4
21.60
23.57
umol/l
—
5
14
7
26
2.85
1.62
2.4
1.4
464.43
427.69
mu/l
—
7
26
5
15
3.48
1.54
4.4
2.3
54.60
32.67
mmol/l
—
5
15
5
15
3.48
1.54
1.6
4.9
1497.00
230.58
ug/l
—
5
15
6
21
3.00
1.53
1.2
2.6
0.94
0.11
nmol/l
—
6
16
46
356
1.70
1.47
5.3
3.2
1.17
1.20
mmol/l
0.09
46
338
26
173
1.75
1.43
18.9
9.5
5.12
5.05
kpa
0.25
26
164
0
37
0.00
1.38
0.0
8.0
—
133.16
—
0
37
5
17
3.07
1.38
2.0
6.6
—
—
—
0
0
25
166
1.74
1.38
19.2
8.7
9.60
9.80
kpa
0.20
25
158
26
176
1.71
1.34
15.9
10.5
—
—
—
0
0
30
213
1.66
1.29
7.5
3.8
0.00
0.00
estimate
—
5
34
8
36
2.36
1.28
2.9
2.3
—
—
—
0
0
47
375
1.63
1.26
4.6
3.4
2.71
2.71
mmol/l
0.01
47
354
6
26
2.41
1.21
5.0
23.3
22.33
23.61
mmol/l
—
6
26
18
114
1.75
1.15
4.5
5.3
—
—
—
0
0
16
98
1.79
1.14
12.4
9.9
1.96
1.32
%
0.68
16
93
29
210
1.60
1.13
10.7
5.5
0.00
0.00
estimate
—
5
41
29
210
1.60
1.13
7.7
3.8
0.00
0.00
estimate
—
5
36
9
47
2.03
1.06
1.4
1.4
—
—
—
0
0
15
92
1.78
1.06
2.5
1.8
109.71
98.99
pmol/l
—
7
42
46
375
1.54
1.06
4.6
3.3
1.30
1.30
mmol/l
0.01
46
354
32
241
1.55
1.05
13.8
5.4
51.37
7.50
e6/l
0.73
27
169
27
196
1.57
1.03
21.0
12.4
25.64
25.01
mmol/l
0.49
27
196
18
118
1.68
1.02
1.8
1.7
—
—
—
0
0
0
29
0.00
1.00
0.0
5.2
—
—
—
0
0
0
28
0.00
1.00
0.0
1.1
—
—
—
0
0
46
379
1.51
0.98
4.9
3.4
4.29
4.34
mmol/l
0.14
46
362
8
42
2.00
0.92
2.3
2.0
—
—
—
0
0
14
88
1.72
0.92
2.2
2.0
—
—
—
0
0
14
88
1.72
0.92
10.1
4.0
—
—
—
0
0
6
29
2.15
0.91
9.2
4.7
16.67
8.34
%
—
6
29
6
29
2.15
0.91
9.2
4.7
62.67
69.07
%
—
6
29
6
29
2.15
0.91
7.8
4.6
30.47
36.57
%
—
6
29
40
324
1.48
0.90
12.5
4.2
—
—
—
0
0
19
131
1.59
0.89
8.2
4.1
1.14
0.44
e6/l
0.59
14
75
6
31
2.01
0.86
9.0
4.4
0.82
1.33
e9/l
—
6
22
8
48
1.74
0.81
1.4
1.2
—
—
—
0
0
9
53
1.79
0.79
1.7
1.3
28.98
19.11
nmol/l
—
9
47
9
56
1.68
0.75
1.1
1.9
—
—
—
0
0
14
94
1.59
0.73
12.4
6.6
4.21
12.14
umol/l
1.04
14
78
5
27
1.91
0.69
2.4
18.4
0.76
0.63
%
—
5
27
19
140
1.47
0.66
12.3
3.7
6.82
3.17
e6/l
0.29
19
129
13
88
1.57
0.65
2.2
1.4
—
—
—
0
0
5
29
1.77
0.65
2.4
17.2
0.88
1.59
%
—
5
29
8
49
1.70
0.64
1.3
1.8
—
—
—
0
0
16
115
1.49
0.63
2.9
2.0
—
—
—
0
0
5
30
1.71
0.62
9.2
4.7
214.00
288.00
e6/l
—
5
20
18
133
1.46
0.62
4.4
3.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.5
—
2.32
—
0
20
8
53
1.57
0.60
1.5
2.2
—
—
—
0
0
43
371
1.35
0.60
12.3
12.3
—
—
—
0
0
49
437
1.32
0.52
13.5
14.8
3.80
3.54
e9/l
0.24
42
352
7
46
1.57
0.50
1.7
1.3
—
—
—
0
0
15
112
1.42
0.49
1.9
2.0
1.27
1.32
mmol/l
0.09
15
107
12
86
1.47
0.48
2.3
1.5
—
—
—
0
0
66
620
1.39
0.44
18.0
12.9
24.68
23.94
mg/l
0.06
52
413
5
31
1.65
0.44
9.8
5.0
18.00
17.61
%
—
5
31
19
152
1.33
0.42
10.8
7.4
1.24
1.30
inr
—
5
37
0
15
0.00
0.41
0.0
6.9
—
24.15
—
0
15
10
71
1.47
0.41
2.3
1.9
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
5
34
1.50
0.41
25.6
4.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
4.4
—
—
—
0
0
16
126
1.34
0.39
1.2
1.3
—
—
—
0
0
10
72
1.45
0.39
1.4
1.7
—
—
—
0
0
10
72
1.45
0.39
1.3
1.7
—
—
—
0
0
9
70
1.32
0.38
1.4
1.7
—
—
—
0
0
10
73
1.42
0.36
1.4
1.7
—
—
—
0
0
24
206
1.24
0.31
15.0
4.4
—
—
—
0
0
9
72
1.28
0.27
1.4
1.7
—
—
—
0
0
12
147
0.78
0.26
1.8
1.4
—
—
—
0
0
9
76
1.21
0.26
2.7
10.4
105.33
104.36
mmol/l
—
9
76
5
37
1.37
0.24
1.0
2.1
—
—
—
0
0
10
79
1.30
0.23
3.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
326.90
—
0
10
0
10
0.00
0.21
0.0
17.6
—
1.22
—
0
10
0
12
0.00
0.21
0.0
2.8
—
2.19
—
0
12
6
47
1.30
0.21
1.3
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
7.3
—
—
—
0
0
21
185
1.18
0.21
2.2
1.9
—
—
—
0
0
6
52
1.17
0.19
1.8
1.3
—
—
—
0
0
8
70
1.16
0.17
4.8
3.4
136.22
102.72
mg/l
—
8
61
42
396
1.13
0.16
15.5
13.2
0.00
0.03
e9/l
0.50
33
294
26
242
1.11
0.11
1.7
2.3
—
—
—
0
0
27
253
1.10
0.10
1.6
1.8
1.71
1.59
g/l
0.25
12
113
7
68
1.03
0.08
6.3
4.0
16.19
4.07
mg/mmol
—
7
57
12
119
1.01
0.00
1.8
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.6
—
0.54
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
12.8
—
706.75
—
0
8
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
8.64
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
3.86
—
0
9
0
8
0.00
-0.00
0.0
29.9
—
0.57
—
0
8
0
8
0.00
-0.00
0.0
9.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
14.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: Q17_BILATERAL_CRYPTORCHIDISM – Bilateral cryptorchidism (undescended testicles)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).