cryptorchidism: The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly males |
226837 |
2. Check conditionsNone |
226837 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
400 |
4. Check minimum number of eventsNone |
400 |
5. Include endpointsNone |
400 |
6. Filter based on genotype QC (FinnGen only) |
400 |
Control definitions (FinnGen only)
- Control exclude
- Q17_CONGEN_MALFO_GENITAL_ORGANS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF12
- Parent code in ICD-10
- Q5
- Name in latin
- Retentio testis
Similar endpoints
↥List of similar endpoints to
Undescended testicle
based on the number of shared cases.
Similar with more cases:
- Congenital malformations of genital organs
- Congenital malformations, deformations and chromosomal abnormalities
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 400 | - | 400 |
| Unadjusted period prevalence (%) | 0.18 | - | 0.18 |
| Median age at first event (years) | 6.92 | - | 6.92 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 367
- Matched controls
- 3660
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q53.1
ICD-10 Finland
Undescended testicle, unilateral
+∞
323.0
297
*
KFH00
NOMESCO Finland
Operation for undescended or ectopic testis
+∞
198.3
172
*
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
+∞
79.0
73
*
KFH10
NOMESCO Finland
Orchiopexy
119.0
72.0
76
8
Q55.20
ICD-10 Finland
Retractile testis
117.6
48.1
51
5
Q53.9
ICD-10 Finland
Undescended testicle, unspecified
+∞
36.0
34
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
9.3
27.4
59
74
KFC00
NOMESCO Finland
Unilateral orchiectomy
19.8
27.2
41
23
G03GA01
ATC
chorionic gonadotrophin; parenteral
37.6
22.4
28
8
Q53.0
ICD-10 Finland
Ectopic testis
+∞
18.9
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
15.8
146
728
JAH01
NOMESCO Finland
Laparoscopy
14.0
14.9
25
19
7525A
ICD-9 Finland
Congenital anomalies of genital organs, Undescended testicle[RETENTIO TESTIS (CRYPTORCHISMUS)]
16.2
14.6
23
15
ZXA00
NOMESCO Finland
Right side
3.0
14.1
92
365
H01AC01
ATC
somatropin; parenteral
5.6
12.1
35
67
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
3.6
11.4
53
163
F82
ICD-10 Finland
Specific developmental disorder of motor function
5.2
11.0
34
71
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
4.9
10.6
34
74
75210
ICD-8 Finland
Congenital anomalies of genital organs, Undescended testicle
112.7
10.5
11
*
Q53
ICD-10 Finland
Undescended testicle
+∞
10.4
10
*
ZXA05
NOMESCO Finland
Left side
2.7
10.4
81
351
7505
FHL
Funicular lysis and orchidopexy
12.6
9.9
17
14
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.5
9.8
85
391
101
Kela drug reimbursment
Anterior pituitary hypofunction
5.8
9.5
26
47
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
8.7
101
538
E29.1
ICD-10 Finland
Testicular hypofunction
11.1
8.3
15
14
N50.0
ICD-10 Finland
Atrophy of testis
34.0
8.1
10
*
ZXA10
NOMESCO Finland
Bilateral
2.3
8.0
79
387
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
16.1
7.3
11
7
301
Kela drug reimbursment
Growth hormone
6.9
6.9
16
24
R62.0
ICD-10 Finland
Delayed milestone
3.1
6.8
38
133
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.3
6.8
24
59
121
Kela drug reimbursment
Severe hypofunction of sexual glands
17.0
6.8
10
6
F83
ICD-10 Finland
Mixed specific developmental disorders
3.1
6.6
35
121
602
Kela drug reimbursment
Children's severe malnutrition
3.7
6.4
26
73
WX110
NOMESCO Finland
Local anesthesy
1.8
6.3
245
1943
Q54.2
ICD-10 Finland
Hypospadias, penoscrotal
+∞
6.3
6
*
Q55.1
ICD-10 Finland
Hypoplasia of testis and scrotum
+∞
6.3
6
*
Z51.80
ICD-10 Finland
Manipulation of puberty development with hormone therapy
27.1
6.2
8
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
49
135
3.99
16.00
2.9
2.1
11.0
5.5
iu/l
1.41
33
84
93
385
2.84
15.76
3.8
2.2
12.2
14.6
nmol/l
1.87
84
330
56
182
3.41
14.31
2.9
2.0
6.9
4.1
u/l
1.55
34
124
9
6
15.26
5.92
2.2
1.0
16.9
39.0
ug/l
—
9
6
45
215
2.23
5.42
4.9
12.2
90.8
88.0
%
0.36
45
215
17
56
3.12
4.27
6.6
5.9
2.0
2.0
ug/l
0.02
17
56
74
465
1.72
4.01
4.6
5.8
1457.6
1590.6
ng/l
0.08
66
380
227
1858
1.50
3.89
3.7
2.9
15.0
14.8
pmol/l
0.56
210
1688
88
596
1.61
3.56
8.0
9.4
2.1
1.2
mmol/l
1.89
70
467
227
1879
1.47
3.55
4.6
4.4
36.9
38.7
mmol/mol
1.89
212
1789
126
933
1.51
3.42
4.0
4.2
—
—
—
0
0
131
1000
1.46
3.00
4.5
3.5
72.6
69.2
nmol/l
0.65
124
946
72
485
1.59
2.96
3.9
6.7
30.6
31.1
s
0.48
72
478
21
97
2.22
2.80
1.8
1.5
332.2
311.7
mu/l
0.11
21
92
258
2241
1.42
2.79
3.9
3.4
2.0
2.1
mu/l
0.33
243
2070
305
2734
1.47
2.76
17.5
14.7
4.0
4.0
mmol/l
0.11
296
2654
83
597
1.49
2.53
3.4
3.3
—
—
—
0
0
19
88
2.21
2.53
1.3
1.9
—
—
—
0
0
18
83
2.22
2.43
1.4
1.9
—
—
—
0
0
67
466
1.52
2.40
3.2
4.4
1.7
1.8
mg/l
0.07
44
337
17
77
2.26
2.39
1.3
1.4
386.5
354.2
ug/g
0.27
11
46
302
2729
1.42
2.38
17.6
14.7
139.7
139.6
mmol/l
0.54
294
2661
163
1336
1.37
2.38
5.4
3.4
14.2
3525.6
e6/l
—
5
21
91
679
1.44
2.30
3.4
3.5
2.4
2.4
mmol/l
0.36
84
617
228
1977
1.35
2.27
3.0
3.1
5.8
5.7
mmol/l
0.26
210
1819
14
61
2.34
2.16
2.8
5.1
98.9
95.3
%
0.21
14
61
25
138
1.86
2.13
16.3
15.7
24.3
24.3
mmol/l
0.00
25
133
182
1545
1.32
2.02
8.3
7.5
6.3
6.4
mmol/l
0.52
171
1487
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
7
23
3.07
1.80
1.6
2.1
87.4
114.3
%
—
7
23
12
54
2.25
1.74
5.0
4.5
22.3
23.4
umol/l
0.21
12
54
84
648
1.37
1.74
4.3
4.2
1.7
1.8
ug/l
0.34
74
577
245
2194
1.29
1.72
3.5
3.5
4.4
4.4
mmol/l
0.32
236
2080
16
83
1.96
1.65
1.3
1.9
—
—
—
0
0
59
436
1.41
1.58
4.1
4.2
366.5
1052.6
ng/l
1.47
46
297
330
3094
1.36
1.57
17.8
14.9
40.6
41.1
%
0.44
287
2672
244
2199
1.27
1.56
3.7
3.6
2.8
2.7
mmol/l
0.10
231
2059
6
21
2.88
1.50
1.3
2.1
105.2
119.8
%
—
6
21
119
988
1.29
1.48
8.6
7.9
38.3
37.4
g/l
1.19
111
942
10
45
2.25
1.46
1.3
1.3
—
—
—
0
0
20
117
1.74
1.46
4.3
6.9
25.6
24.3
mmol/l
0.79
20
112
46
331
1.44
1.43
4.1
3.9
0.2
0.2
g/l
0.27
46
311
203
1804
1.25
1.41
7.1
6.9
128.8
113.8
u/l
1.17
192
1720
232
2095
1.25
1.38
3.5
3.2
1.2
1.3
mmol/l
0.28
220
1976
120
1008
1.27
1.35
4.5
3.2
86.0
107.9
ug/l
1.43
120
954
20
121
1.68
1.32
1.7
2.1
—
—
—
0
0
21
129
1.66
1.31
1.7
3.6
59.0
78.7
ml/min/173m2
—
5
46
238
2173
1.23
1.21
3.5
3.3
1.3
1.3
mmol/l
0.21
229
2046
15
88
1.73
1.12
1.7
1.3
—
—
—
0
0
5
21
2.39
1.09
8.2
8.3
—
—
—
0
0
19
121
1.59
1.06
1.7
2.1
—
—
—
0
0
57
449
1.31
1.05
3.5
4.0
9112.7
4794.3
umol/l
0.20
52
402
21
138
1.55
1.04
1.4
1.4
—
—
—
0
0
313
2964
1.24
1.02
9.9
9.4
31.9
32.2
u/l
0.06
302
2875
155
1374
1.20
1.02
16.6
11.4
1.2
1.2
mmol/l
0.58
144
1248
9
157
0.56
1.00
1.7
1.8
—
—
—
0
0
9
49
1.85
0.99
2.0
1.8
—
—
—
0
0
47
364
1.33
0.98
2.9
2.7
0.6
0.7
ug/l
0.87
29
203
74
615
1.25
0.91
2.1
1.7
106.6
97.4
pmol/l
0.70
40
313
62
505
1.27
0.91
4.2
3.9
26.0
21.8
%
0.58
27
200
6
29
2.08
0.89
10.7
11.7
—
—
—
0
0
33
247
1.36
0.87
1.8
2.5
39.4
34.9
u/l
0.12
25
216
362
3503
1.32
0.87
20.5
17.4
141.1
140.9
g/l
0.09
356
3453
14
89
1.59
0.81
1.6
1.9
1.0
1.3
g/l
0.79
14
77
146
1311
1.17
0.80
18.2
12.3
1.2
1.2
mmol/l
0.38
139
1236
32
242
1.35
0.80
13.8
13.2
15.6
13.8
kpa
0.80
32
231
0
24
0.00
0.79
0.0
1.4
—
—
—
0
0
0
24
0.00
0.79
0.0
1.4
—
—
—
0
0
6
33
1.83
0.79
2.2
1.6
30.2
35.0
mg/l
—
6
27
6
33
1.83
0.79
2.2
1.6
29.1
76.9
mg/l
—
6
27
45
359
1.28
0.79
1.7
1.4
22.2
19.1
nmol/l
0.67
40
309
213
1975
1.16
0.77
10.9
9.4
101.1
99.1
ml/min/173m2
0.44
162
1483
6
34
1.77
0.76
2.2
1.6
—
1.4
—
0
5
21
149
1.43
0.76
1.4
1.3
—
—
—
0
0
5
25
2.01
0.72
1.0
1.4
—
—
—
0
0
5
25
2.01
0.72
1.2
1.6
—
—
—
0
0
19
262
0.71
0.72
1.2
1.2
8.3
3.2
u/ml
—
9
190
25
186
1.36
0.71
2.1
1.6
—
—
—
0
0
316
3031
1.19
0.71
14.8
12.0
24.3
24.9
mg/l
0.12
228
2113
5
26
1.93
0.70
7.8
6.9
—
—
—
0
0
5
26
1.93
0.70
1.2
1.2
234.8
188.7
iu/ml
—
5
26
5
26
1.93
0.70
8.2
7.0
—
—
—
0
0
120
1078
1.16
0.65
4.3
3.3
0.0
0.0
estimate
0.00
16
172
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
6
104
0.57
0.62
1.0
1.1
—
—
—
0
0
23
173
1.35
0.62
2.1
3.7
30.6
30.1
%
0.09
16
126
6
105
0.56
0.62
1.0
1.1
—
—
—
0
0
5
30
1.67
0.61
1.6
1.3
—
—
—
0
0
51
600
0.83
0.61
2.2
2.3
—
—
—
0
0
118
1065
1.15
0.60
4.2
3.3
0.0
0.0
estimate
0.00
17
171
118
1067
1.15
0.58
6.4
4.8
0.0
0.0
estimate
0.00
17
188
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
6
35
1.72
0.58
2.7
1.5
—
—
—
0
0
12
81
1.49
0.57
5.8
3.7
—
—
—
0
0
67
581
1.18
0.57
18.0
9.4
1.4
1.1
mmol/l
0.60
56
413
14
98
1.44
0.56
2.2
1.4
—
—
—
0
0
14
98
1.44
0.56
2.2
1.4
—
—
—
0
0
131
1196
1.14
0.56
7.8
7.8
19.8
22.6
umol/l
0.35
119
1138
6
37
1.63
0.55
1.2
1.4
248.5
250.9
pmol/l
—
6
32
9
59
1.53
0.55
2.1
1.9
—
—
—
0
0
9
65
1.39
0.50
2.1
2.2
—
—
—
0
0
12
85
1.42
0.47
1.5
2.4
1.0
0.4
nmol/l
2.40
12
74
83
745
1.14
0.46
4.0
3.2
—
—
—
0
0
10
69
1.46
0.44
2.5
2.8
131.4
134.0
g/l
—
5
60
7
51
1.38
0.44
1.6
1.7
—
—
—
0
0
10
70
1.44
0.41
1.3
2.4
—
—
—
0
0
106
974
1.12
0.41
7.0
4.1
—
—
—
0
0
58
513
1.15
0.40
2.1
3.2
1.0
1.0
kg/l
0.12
11
69
22
177
1.25
0.40
2.1
1.7
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
34
1.47
0.40
1.6
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
7.6
—
0
13
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
60
534
1.14
0.39
5.8
3.5
0.4
0.4
e6/l
0.00
44
310
91
832
1.12
0.39
7.7
3.9
0.3
0.2
e6/l
0.12
74
628
5
36
1.39
0.38
1.6
1.3
—
—
—
0
0
24
197
1.23
0.38
14.3
12.2
125.0
129.2
g/l
0.39
24
190
9
68
1.33
0.37
1.3
1.1
—
148.3
—
0
19
8
111
0.71
0.37
8.3
11.4
26.6
23.9
mmol/l
—
8
102
31
262
1.20
0.37
2.6
2.7
2.4
2.4
mmol/l
0.16
26
223
33
282
1.18
0.36
1.3
1.7
465.5
456.8
pmol/l
0.07
28
247
283
2899
0.91
0.35
3.6
3.6
—
—
—
0
0
20
163
1.24
0.34
1.6
1.3
200.9
108.7
iu/ml
—
7
47
60
540
1.13
0.34
5.8
3.6
0.6
0.5
e6/l
0.10
43
317
16
198
0.80
0.33
1.5
1.2
—
—
—
0
0
15
118
1.28
0.33
1.2
1.1
—
—
—
0
0
193
1845
1.08
0.32
4.3
4.2
6.3
7.7
mm/h
1.51
180
1720
7
54
1.30
0.30
1.0
1.5
—
—
—
0
0
22
259
0.84
0.30
1.3
1.3
—
—
—
0
0
13
161
0.80
0.28
4.5
6.8
—
—
—
0
0
8
66
1.21
0.27
1.0
1.0
1.4
1.4
g/l
—
8
57
195
1878
1.07
0.25
11.1
11.8
3.7
3.7
e9/l
0.08
164
1564
27
307
0.87
0.25
1.0
1.1
—
—
—
0
0
9
76
1.19
0.24
6.7
3.7
21.1
25.9
%
—
9
76
45
409
1.11
0.23
2.3
2.0
—
—
—
0
0
11
88
1.25
0.22
1.0
1.1
—
5.8
—
0
16
96
1010
0.93
0.22
1.6
1.6
7.2
1.8
u/ml
0.49
19
188
5
41
1.22
0.22
1.0
1.0
—
—
—
0
0
5
41
1.22
0.22
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
49.7
—
0
12
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
12
98
1.23
0.21
1.5
3.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
10
81
1.24
0.18
1.2
1.4
—
—
—
0
0
35
320
1.10
0.17
2.2
1.9
—
—
—
0
0
54
505
1.08
0.16
4.3
3.6
0.0
0.0
estimate
0.50
14
172
11
130
0.84
0.16
10.6
3.3
37.4
35.8
umol/l
0.14
11
123
53
560
0.94
0.14
2.0
2.2
—
—
—
0
0
35
326
1.08
0.12
2.3
2.0
—
—
—
0
0
14
156
0.89
0.10
2.7
2.1
—
—
—
0
0
21
192
1.10
0.10
2.1
2.4
—
—
—
0
0
19
206
0.92
0.09
2.6
1.9
—
—
—
0
0
6
56
1.07
0.08
1.2
1.3
—
—
—
0
0
67
646
1.04
0.08
3.0
3.1
58.2
58.0
u/l
0.01
62
610
5
60
0.83
0.08
1.0
1.0
145.0
165.4
g/l
—
5
60
62
640
0.96
0.08
3.3
3.2
20.4
57.9
ng/l
1.07
43
397
7
67
1.04
0.08
1.6
1.6
—
—
—
0
0
7
68
1.03
0.08
1.3
1.7
—
—
—
0
0
14
153
0.91
0.07
2.8
2.2
—
92.1
—
0
13
19
204
0.93
0.07
2.6
1.9
213.3
173.0
u/ml
0.44
11
90
8
75
1.07
0.07
1.9
2.0
—
—
—
0
0
26
245
1.06
0.06
1.2
1.2
11.0
2.3
u/ml
—
7
80
19
177
1.07
0.06
1.5
1.4
—
—
—
0
0
27
282
0.95
0.05
1.1
1.2
76.9
16.1
iu/ml
—
8
65
109
1105
0.98
0.05
2.0
1.8
—
—
—
0
0
180
1814
0.98
0.05
3.7
3.9
35.9
39.8
u/l
0.57
171
1732
14
149
0.93
0.04
2.7
1.7
—
—
—
0
0
19
197
0.96
0.02
1.4
1.2
—
—
—
0
0
11
106
1.04
0.00
6.3
11.6
23.4
23.2
mmol/l
0.08
11
98
19
184
1.03
0.00
1.4
1.3
—
—
—
0
0
19
191
0.99
0.00
3.4
1.6
—
—
—
0
0
22
221
0.99
0.00
2.1
2.5
—
—
—
0
0
19
190
1.00
0.00
2.2
2.7
—
—
—
0
0
0
9
0.00
0.00
0.0
2.4
—
—
—
0
0
9
92
0.98
0.00
1.3
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
109.3
—
0
8
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
8
81
0.98
0.00
1.5
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
335.8
—
0
5
0
5
0.00
0.00
0.0
4.8
—
56.6
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
6
64
0.93
0.00
1.8
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
33.9
—
0
6
0
7
0.00
0.00
0.0
4.3
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: Q17_UNDES_TESTICLE – Undescended testicle
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).