Pseudosarcomatous fibromatosis

M13_PSEUDOSARCFIBROMATOSIS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M72.4 Cause of death: ICD-10 — M72.4 2 out of 7 registries used, show all original rules.	28
4. Check minimum number of events None	28
5. Include endpoints None	28
6. Filter based on genotype QC (FinnGen only)	28

Control definitions (FinnGen only)

Control exclude: M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M72
Name in latin: Fibromatosis pseudosarcomatosa

NAME	M13_PSEUDOSARCFIBROMATOSIS
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M724
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M724
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Pseudosarcomatous fibromatosis based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	192	108	83
Only index persons	181	105	76
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	56.29	55.46	57.63
Only index persons	55.93	54.70	57.63

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	28	17	11
Unadjusted period prevalence (%)	0.01	0.01	0.00
Median age at first event (years)	53.19	48.59	60.30

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3026493) Urate [Moles/volume] in Serum or Plasma

4.41

3.49

1.2

2.8

321.3

13625.3

umol/l

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

8.36

2.66

1.2

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

3.88

2.22

2.3

1.5

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

4.81

1.91

1.2

2.1

0.3

0.2

g/l

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

108

2.87

1.83

3.9

3.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

2.87

1.82

2.1

1.9

—

(3019225) pH of Specimen

3.52

1.68

2.0

4.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

3.34

1.60

1.3

1.5

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.99

1.57

2.7

8.5

104.7

mmol/l

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

173

2.84

1.41

6.1

6.4

74.3

74.9

u/l

0.05

160

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

2.41

1.39

2.4

1.7

94.9

89.6

pmol/l

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

123

2.30

1.20

3.2

4.1

5.8

6.5

mmol/l

1.59

113

(3044889) 12 lead EKG panel

158

2.31

1.15

5.0

3.2

—

(3044640) Blood type and Crossmatch panel - Blood

2.17

1.07

2.3

1.9

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

2.04

0.97

3.2

3.8

37.8

35.8

g/l

1.00

(42870588) Differential panel, method unspecified - Blood

2.13

0.95

3.2

4.3

—

(3042936) Bacteria identified in Isolate by Culture

2.18

0.90

1.8

1.6

—

(3023368) Bacteria identified in Blood by Culture

1.93

0.85

3.0

4.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.84

0.0

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.84

0.0

1.6

—

(3013512) EKG study

1.99

0.82

3.5

3.7

—

(3002256) Pathology report gross observation

2.12

0.81

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

1.94

0.80

1.5

2.9

—

(40768797) Stomach Pathology biopsy report

2.21

0.77

1.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.88

0.67

1.6

—

(3003694) ABO and Rh group [Type] in Blood

1.63

0.60

1.2

1.3

—

(3019150) Specific gravity of Urine by Refractometry

1.78

0.55

2.1

2.3

—

1.0

—

(40758558) Short blood count panel - Blood

1.53

0.47

1.6

9.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

149

1.58

0.45

3.6

3.5

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

1.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.47

0.40

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.46

0.37

1.2

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.42

0.36

5.0

3.0

—

(3021589) Normoblasts [#/volume] in Blood

1.41

0.28

4.7

8.0

0.0

e9/l

—

(1761868) Lipid panel - Serum or Plasma

0.70

0.28

2.3

2.8

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.35

0.22

2.2

2.8

—

(3021960) Folate [Moles/volume] in Serum or Plasma

1.28

0.22

1.7

1.5

25.0

21.3

nmol/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

1.3

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.20

0.0

2.2

—

(3026008) Bacteria identified in Urine by Culture

1.27

0.20

2.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.25

0.13

2.3

2.7

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.13

0.10

1.0

1.2

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

127

0.90

0.02

3.6

5.1

9.8

12.4

umol/l

0.55

121

(40768804) Tissue Pathology biopsy report

104

1.10

0.01

2.9

2.1

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

155

0.93

0.00

2.7

2.8

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.0

1.2

—

(4094501)

0.00

0.0

1.0

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.1

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

4.2

—

129.2

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.0

2.3

—

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.1

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

1.3

—

(3041096) Erythrocytes [Presence] in Urine by Automated

0.83

0.00

2.0

2.4

—

(3000330) Specific gravity of Urine by Test strip

0.00

0.0

4.6

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.2

—

(3025941) Bacteria identified in Stool by Culture

0.00

0.0

1.2

—

(3003338) MCHC [Mass/volume]

205

1.10

0.00

23.0

14.4

334.6

332.4

g/l

0.64

205

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.0

1.0

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.0

4.0

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.0

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.7

—

(3045414) Leukocytes [Presence] in Urine

0.00

0.0

1.8

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.0

2.3

—

0.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

222

0.96

0.00

17.7

12.9

41.8

40.0

0.73

170

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.3

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

77.9

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

0.92

0.00

4.6

2.5

61.0

115.3

ug/l

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

0.0

1.4

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.1

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.3

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

0.00

0.0

1.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_PSEUDOSARCFIBROMATOSIS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_PSEUDOSARCFIBROMATOSIS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_PSEUDOSARCFIBROMATOSIS – Pseudosarcomatous fibromatosis

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Pseudosarcomatous fibromatosis

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints