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Respiratory conditions due to other external agents

EFO MESH Endpoint Browser PheWeb

J10_RESPCONDEXT

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — J70
  • Hospital discharge: ICD-9 — 508
  • Cause of death: ICD-10 — J70
  • Cause of death: ICD-9 — 508

2 out of 7 registries used, show all original rules.

758

4. Check minimum number of events

None

758

5. Include endpoints

None

758

6. Filter based on genotype QC (FinnGen only)

740

Control definitions (FinnGen only)

Control exclude
J10_EXTERLUNG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J60-J70
Name in latin
Morbositates respiratoriae ex aliis agentibus externis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5135 2989 2077
Only index persons 3638 2249 1389
Unadjusted period prevalence (%)
Whole population 0.07 0.09 0.06
Only index persons 0.07 0.08 0.05
Median age at first event (years)
Whole population 69.92 70.17 69.46
Only index persons 67.98 67.98 67.97

-FinnGen-

Key figures

All Female Male
Number of individuals 740 427 313
Unadjusted period prevalence (%) 0.15 0.15 0.14
Median age at first event (years) 66.99 64.12 70.90

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
758
Matched controls
7580
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
+∞
312.9
278
*
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
+∞
309.2
275
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
14.7
206.0
209
191
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.7
127.6
217
376
H02AB06
ATC
prednisolone; systemic
7.8
126.2
622
2809
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.5
118.3
246
520
TGC00
NOMESCO Finland
Bronchial lavation
13.4
112.7
113
98
H02AB02
ATC
dexamethasone; systemic
6.0
108.3
244
552
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
9.5
98.5
127
157
A04AA02
ATC
granisetron; systemic, transdermal
7.3
96.9
162
271
XX3DW
NOMESCO Finland
Time consuming IT work
5.5
90.8
220
524
A03FA01
ATC
metoclopramide; systemic, rectal
4.5
89.5
341
1166
GD1AD
NOMESCO Finland
Thorax CT examination
7.5
89.1
143
228
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.2
83.6
383
1483
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
10.3
75.4
89
97
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
12.1
73.9
77
70
J70.4
ICD-10 Finland
Drug-induced interstitial lung disorders, unspecified
+∞
73.1
69
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.1
71.6
537
2817
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
20.1
71.5
56
30
115
Kela drug reimbursment
Breast cancer
5.0
70.1
179
439
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.4
67.5
154
342
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.5
64.5
141
301
ZX070
NOMESCO Finland
Intensity modified radiotherapy
12.4
61.0
62
54
WF049
NOMESCO Finland
Radiotherapy of metastasis
7.7
58.8
87
125
JN4AD
NOMESCO Finland
Body CT examination
4.5
58.6
172
467
130
Kela drug reimbursment
Malignant tumour
4.6
56.7
158
411
J70.3
ICD-10 Finland
Chronic drug-induced interstitial lung disorders
+∞
55.9
53
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
5.2
55.7
128
284
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
6.2
54.9
102
186
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.5
52.3
111
229
JN4BD
NOMESCO Finland
Extensive body CT
4.1
51.6
172
510
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
18.8
51.0
41
23
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.4
50.4
89
154
J70.1
ICD-10 Finland
Chronic and other pulmonary manifestations due to radiation
+∞
49.5
47
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
7.2
49.3
77
117
HA1AA
NOMESCO Finland
X-ray mammography
4.3
48.0
143
389
D70.82
ICD-10 Finland
Drug-induced neutropenia
10.7
47.4
53
53
WZC00
NOMESCO Finland
Treatment plan or consultation
3.0
47.2
368
1826
ZX080
NOMESCO Finland
Image guided radiotherapy
8.0
46.9
66
89
J01MA12
ATC
levofloxacin; systemic
3.2
46.1
247
990
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
7.3
45.7
70
104
A04AA55
ATC
palonosetron, combinations; systemic
6.5
45.5
79
134
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
10.6
43.8
49
49
L02BG04
ATC
letrozole; oral
4.4
43.6
125
329
L03AA14
ATC
lipegfilgrastim; parenteral
8.9
42.9
55
66
WF003
NOMESCO Finland
Adjuvant radiotherapy
6.5
41.7
71
118
R50.9
ICD-10 Finland
Fever, unspecified
3.4
41.6
185
658
WZC30
NOMESCO Finland
Teaching
3.3
40.5
196
733
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.8
40.1
98
227
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
15.2
39.3
35
24
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
4.4
39.2
108
275
L03AA13
ATC
pegfilgrastim; parenteral
4.9
37.5
89
201
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
11.7
37.4
39
35
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.2
37.3
109
290
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.3
36.4
160
561
WF002
NOMESCO Finland
Radical radiotherapy
4.7
35.7
90
213
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
35.4
385
2174
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
11.8
34.7
36
32
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
5.5
34.6
70
137
N02AA05
ATC
oxycodone; systemic
2.8
34.3
229
1014
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
4.5
34.2
91
225
R06.0
ICD-10 Finland
Dyspnoea
2.6
33.5
305
1573
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
4.9
33.0
76
167
J70.9
ICD-10 Finland
Respiratory conditions due to unspecified external agent
+∞
32.5
31
*
B01AB10
ATC
tinzaparin; parenteral
3.3
31.7
135
462
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
30.5
153
576
A02BC02
ATC
pantoprazole; systemic
2.8
30.5
599
4336
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.1
30.3
91
246
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
6.4
29.7
51
85
Z51.5
ICD-10 Finland
Palliative care
3.4
29.7
118
386
PJA12
NOMESCO Finland
Sentinel node biopsy
3.4
29.0
120
402
C01BD01
ATC
amiodarone; systemic
5.9
28.9
54
98
WF004
NOMESCO Finland
Palliative radiotherapy
7.3
28.7
43
62
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
6.5
28.7
48
78
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
6.2
28.6
50
85
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
28.5
189
825
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
7.0
26.6
41
61
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
26.5
231
1145
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
4.2
26.5
76
198
L01CA04
ATC
vinorelbine; systemic
10.0
26.0
30
31
JN4CD
NOMESCO Finland
Very extensive body CT
4.6
26.0
64
148
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
10.7
25.5
28
27
C03CA01
ATC
furosemide; systemic
2.2
25.4
345
2062
L02BG06
ATC
exemestane; oral
6.5
25.1
42
68
A04AA01
ATC
ondansetron; systemic, rectal
3.3
25.1
104
348
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.8
24.9
59
132
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
10.3
24.8
28
28
ZXE00
NOMESCO Finland
One hour or less
2.2
24.8
352
2134
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
8.7
24.2
31
37
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
8.0
24.0
33
43
HAC20
NOMESCO Finland
Total mastectomy
4.1
23.8
69
181
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
5.9
23.6
43
76
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
4.0
23.6
70
187
L02BG03
ATC
anastrozole; oral
6.5
23.4
39
63
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.0
22.8
116
437
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
7.2
22.6
34
49
X76
ICPC
Malignant neoplasm breast female
5.8
22.5
42
76
N02AA01
ATC
morphine; systemic, rectal
5.8
22.0
41
74
NK6AN
NOMESCO Finland
Total body bone isotope imaging
5.0
21.8
48
101
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.5
21.6
36
58
A04AD12
ATC
aprepitant; systemic
5.6
21.6
42
79
HAB40
NOMESCO Finland
Wedge excision of mammary gland
3.5
21.4
80
250
WW500
NOMESCO Finland
Blood transfusion
4.1
21.1
60
155
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
8.0
20.5
28
36
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
4.2
20.2
56
142
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
4.1
20.1
57
147
J01MA14
ATC
moxifloxacin; systemic
2.9
19.8
105
403
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
3.6
19.8
68
201
XW000
NOMESCO Finland
Bone marrow biopsy
3.9
19.7
60
163
TGD00
NOMESCO Finland
Needle biopsy of lung
20.0
19.6
29
15
M05BX04
ATC
denosumab; parenteral
3.2
19.3
83
283
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
6.8
18.4
29
44
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
8.0
18.4
25
32
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
5.9
18.2
33
58
L04AA13
ATC
[U] leflunomide
5.1
18.0
38
77
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.6
17.9
118
505
C50.99
ICD-10 Finland
Breast, unspecified
4.2
17.8
48
119
M04AA01
ATC
allopurinol; systemic
2.4
17.8
145
685
B01AB05
ATC
enoxaparin; parenteral
2.0
17.7
292
1815
ZXE10
NOMESCO Finland
More than one and less than three hours
2.0
17.5
322
2076
L03AA02
ATC
filgrastim; parenteral
4.3
16.9
44
106
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.0
16.9
229
1324
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
4.6
16.8
41
94
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
6.0
16.3
29
50
ZXD05
NOMESCO Finland
Urgent procedure
2.0
16.2
255
1551
L04AX01
ATC
azathioprine; systemic
4.1
16.0
45
115
A02BC01
ATC
omeprazole; systemic
2.0
16.0
251
1522
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
4.8
16.0
37
81
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
6.3
16.0
27
44
C50
ICD-10 Finland
Malignant neoplasm of breast
4.5
15.9
39
90
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
4.6
15.8
38
86
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.0
15.8
75
270
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
26.9
15.7
21
8
J70.8
ICD-10 Finland
Respiratory conditions due to other specified external agents
163.2
15.5
16
*
ZX120
NOMESCO Finland
Intravenous
2.5
15.5
103
442
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
15.4
117
534
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
13.4
15.3
26
20
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
15.1
93
384
N05CF01
ATC
zopiclone; oral
1.9
14.8
293
1909
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.1
14.7
64
219
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
14.6
110
499
N03AX16
ATC
[U] pregabalin
2.0
14.6
212
1246
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
6.7
14.5
23
35
L02BA01
ATC
tamoxifen; oral
3.3
14.4
57
184
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
13.7
14.3
24
18
JN6AD
NOMESCO Finland
CT of torso and neck
5.8
14.2
26
46
N02AX02
ATC
tramadol; systemic, rectal
1.8
14.2
364
2560
L04AX03
ATC
methotrexate; systemic
2.5
14.0
93
398
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
4.4
14.0
35
82
WX892
NOMESCO Finland
Monitored bed care
2.7
13.9
80
319
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.7
13.8
26
25
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.1
13.7
59
201
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
13.7
107
494
5088A
ICD-9 Finland
Respiratory conditions due to other and unspecified external agents, Respiratory conditions due to other specified external agents[MORBI ORGANORUM RESPIRATIONIS E PHARMACO]
+∞
13.6
13
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
13.1
13.5
23
18
L04AA06
ATC
mycophenolic acid; systemic
6.2
13.5
23
38
XX1XN
NOMESCO Finland
Other isotope examination
9.9
13.3
26
27
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
13.3
382
2762
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.5
13.2
46
137
WX402
NOMESCO Finland
General anaesthesia
2.0
13.2
164
909
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
13.2
156
850
HAB99
NOMESCO Finland
Other partial excision of mammary gland
4.2
13.1
35
86
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
6.1
13.1
23
39
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
6.1
13.1
23
39
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
13.1
96
430
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.9
13.0
64
235
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.0
13.0
59
207
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
4.1
12.8
36
92
R04.2
ICD-10 Finland
Haemoptysis
3.5
12.8
44
130
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.8
12.7
66
250
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
12.6
111
538
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.7
12.6
40
112
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
5.1
12.5
26
52
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
4.8
12.4
28
60
R06AE07
ATC
cetirizine; oral
1.8
12.4
318
2212
R05
ICD-10 Finland
Cough
1.9
12.3
178
1039
C07AB07
ATC
bisoprolol; oral
1.7
12.3
428
3241
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.2
12.2
33
82
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
12.2
43
129
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
12.2
132
694
J96.1
ICD-10 Finland
Chronic respiratory failure
4.0
11.7
33
85
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
19.3
11.6
17
9
SPAT1263
SPAT
Sampling
1.7
11.6
323
2286
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
5.8
11.5
21
37
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.6
11.5
27
60
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
11.4
209
1312
L01BA01
ATC
methotrexate; systemic
3.4
11.2
41
126
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
11.2
141
783
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
8.2
11.1
24
30
A10AC01
ATC
insulin (human); parenteral
2.5
11.0
75
324
A07EC01
ATC
sulfasalazine; oral, rectal
2.5
11.0
75
324
HA013
NOMESCO Finland
Radiotherapy after total ablation of mammary gland
4.8
11.0
25
54
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
10.9
246
1636
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
10.8
10.8
20
19
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
13.1
10.7
18
14
R03AC02
ATC
salbutamol; inhalant
1.7
10.5
411
3157
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.2
10.5
97
479
J01MA02
ATC
ciprofloxacin; systemic
1.7
10.4
313
2244
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
16.3
10.4
16
10
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.1
10.4
108
558
ZX095
NOMESCO Finland
Combined chemoradiotherapy
9.7
10.3
20
21
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
4.8
10.3
23
49
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
19.1
10.3
15
8
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
10.3
166
998
Z31.5
ICD-10 Finland
Genetic counselling
3.1
10.2
42
139
J01CA04
ATC
amoxicillin; systemic
1.8
10.2
590
5007
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
13.3
10.2
17
13
I50.0
ICD-10 Finland
Congestive heart failure
2.2
10.2
86
409
J96.0
ICD-10 Finland
Acute respiratory failure
5.1
10.1
21
42
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
4.6
10.1
24
54
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
9.3
10.1
20
22
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
4.7
10.1
23
50
WF099
NOMESCO Finland
Other radiotherapy
14.8
10.0
16
11
R81
ICPC
Pneumonia
3.2
9.9
39
126
R84
ICPC
Malignant neoplasm bronchus/lung
20.3
9.8
14
7
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.4
9.8
35
106
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
10.8
9.8
18
17
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
3.6
9.7
32
92
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
4.3
9.7
25
60
XG410
NOMESCO Finland
Flow-volume spirometry
3.0
9.6
43
150
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
4.9
9.6
21
44
5088X
ICD-9 Finland
Respiratory conditions due to other and unspecified external agents, Respiratory conditions due to other specified external agents[MORBI ORGANORUM RESP CAUSA EXT ALIA DEFINITA]
+∞
9.4
9
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.7
9.4
49
186
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
22.0
9.4
13
6
ZX050
NOMESCO Finland
Stereotactic radiotherapy
8.8
9.3
19
22
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
8.8
9.3
19
22
NH3EA
NOMESCO Finland
Feet X-ray examination with load
4.1
9.3
25
62
I47.2
ICD-10 Finland
Ventricular tachycardia
3.9
9.3
27
71
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.4
9.2
63
273
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
4.0
9.2
26
67
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
9.2
100
525
I50.1
ICD-10 Finland
Left ventricular failure
2.5
9.1
57
237
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
37.2
9.0
11
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
9.0
119
669
NHQ40
NOMESCO Finland
Amputation of toe
4.3
9.0
23
55
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
4.0
8.9
25
64
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
24.3
8.9
12
5
M01CB01
ATC
sodium aurothiomalate; parenteral
5.0
8.9
19
39
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
8.9
43
157
J01DB01
ATC
cefalexin; oral
1.7
8.8
599
5181
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
3.7
8.8
27
74
R03BB04
ATC
tiotropium bromide; inhalant
2.0
8.8
101
541
M05BA04
ATC
alendronic acid; oral
2.1
8.7
91
470
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
50.6
8.7
10
*
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
3.8
8.7
26
70
A06AD11
ATC
lactulose; oral
1.8
8.7
137
815
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
11.7
8.6
15
13
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.3
8.6
32
100
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
10.2
8.6
16
16
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
4.0
8.5
24
62
L04AD01
ATC
ciclosporin; systemic
4.5
8.4
20
45
P01BA02
ATC
hydroxychloroquine; oral
2.2
8.3
74
359
A02BC05
ATC
esomeprazole; systemic
1.6
8.3
308
2291
ED1AA
NOMESCO Finland
Mandibular X-ray examination
10.9
8.3
15
14
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
8.3
304
2255
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
14.7
8.2
13
9
8140/3-C34.3
ICD-O-3
Adenocarcinoma, NOS, of lower lobe, lung
14.7
8.2
13
9
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
7.7
8.2
18
24
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
4.6
8.2
19
42
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
11.9
8.1
14
12
B01AA03
ATC
warfarin; systemic
1.7
8.1
177
1155
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
10.2
8.1
15
15
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
3.9
8.0
23
60
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
7.3
8.0
18
25
B01AB04
ATC
dalteparin; parenteral
2.5
8.0
48
196
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
4.1
7.8
21
52
A06AH03
ATC
naloxegol; oral
4.3
7.8
20
48
R03AK08
ATC
formoterol and beclometasone; inhalant
2.7
7.8
40
151
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
7.7
156
995
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
7.7
206
1413
A10AB05
ATC
insulin aspart; parenteral
2.2
7.7
62
289
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.4
7.7
53
231
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
8.1
7.6
16
20
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.3
7.6
59
271
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
25.3
7.6
10
*
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
6.3
7.6
19
31
SPAT1262
SPAT
Handing over of treatment supplies
1.7
7.5
140
873
PD5BD
NOMESCO Finland
Extensive CT of aorta
4.0
7.5
21
54
PWG00
NOMESCO Finland
Reoperation on peripheral vessels for thrombosis or embolism
80.9
7.4
8
*
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
13.5
7.4
12
9
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.8
7.4
37
138
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
7.3
59
275
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
3.6
7.3
24
69
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
4.2
7.3
19
46
J94.8
ICD-10 Finland
Other specified pleural conditions
4.2
7.3
19
46
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
9.5
7.3
14
15
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
3.9
7.3
21
55
TQW20
NOMESCO Finland
Tatoe
5.9
7.3
19
33
J01AA02
ATC
doxycycline; systemic
1.6
7.1
581
5080
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
6.1
7.1
18
30
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.8
7.0
21
57
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
6.9
156
1022
H02AB09
ATC
hydrocortisone; systemic
3.6
6.9
22
62
SPAT1255
SPAT
Intravenous administration of medicine
2.2
6.9
58
276
XX9TE
NOMESCO Finland
Compementary ultrasound examination
8.4
6.8
14
17
I70.0
ICD-10 Finland
Atherosclerosis of aorta
11.1
6.8
12
11
YX8BD
NOMESCO Finland
Stereotactic extensive CT examination for dose design of radiotherapy
11.1
6.8
12
11
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
6.8
85
468
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
16.9
6.8
10
6
WW200
NOMESCO Finland
Immunization
3.5
6.7
23
68
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
6.7
309
2384
D70.89
ICD-10 Finland
Neutropenic splenomegaly
6.0
6.6
17
29
R02
ICPC
Shortness of breath/dyspnoea
1.8
6.6
109
654
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
6.6
88
495
8070/3-C34.1
ICD-O-3
Squamous cell carcinoma, NOS, of upper lobe, lung
8.8
6.6
13
15
J01FF01
ATC
clindamycin; systemic
1.6
6.6
200
1409
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
2.8
6.5
31
112
L88
ICPC
Rheumatoid/seropositive arthritis
2.6
6.5
36
141
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.6
6.5
21
60
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
6.4
35
137
TQB05
NOMESCO Finland
Puncture of skin of trunk
6.6
6.4
15
23
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
3.4
6.3
22
66
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.5
6.3
40
168
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
3.9
6.3
18
47
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.9
6.3
18
47
GAA31
NOMESCO Finland
Thoracoscopy
18.2
6.3
9
5
3030
Kela drug reimbursment
Abemaciclib
+∞
6.3
6
*
1515, ,
Kela drug reimbursment
+∞
6.3
6
*
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
7.1
6.2
14
20
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
6.2
63
322
Z3231
NOMESCO Finland
Registered nurse
1.5
6.2
204
1459
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.0
6.2
27
93
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.0
6.2
17
43
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
6.4
6.2
15
24
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.5
6.2
21
62
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
6.1
187
1315
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.6
6.1
34
134
JN5KR
NOMESCO Finland
Very extensive PET-CT of upper body metabolism (eyebrows to thighs)
12.6
6.1
10
8
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
6.1
321
2530
TK800
NOMESCO Finland
Hemodialysis
3.7
6.1
19
53
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
6.0
189
1336

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
88
93
10.57
76.27
2.3
2.8
—
—
—
0
0
405
1811
3.65
67.92
6.6
4.2
—
—
—
0
0
281
1022
3.78
64.09
5.4
3.2
0.80
0.81
mmol/l
0.91
272
945
188
544
4.27
58.88
7.2
3.4
1.23
1.23
mmol/l
0.00
179
473
183
532
4.22
56.80
3.1
2.0
357.29
375.35
nmol/l
0.46
176
480
80
114
7.73
54.36
3.6
3.0
61.86
59.28
%
0.69
80
114
83
124
7.39
54.08
4.1
3.5
—
—
—
0
0
78
109
7.86
53.90
3.2
2.7
4.41
4.48
e9/l
0.07
78
109
503
2827
3.32
53.72
11.7
6.0
—
—
—
0
0
84
131
7.09
52.60
5.1
3.7
2.62
2.65
mmol/l
0.03
67
88
398
1977
3.13
52.30
7.1
3.7
7.41
7.40
ph
1.75
159
367
92
159
6.45
52.20
5.2
3.5
7.44
7.42
ph
4.44
85
140
490
2748
3.21
51.80
10.0
5.6
0.60
0.67
%
1.97
474
2545
186
584
3.90
51.43
1.5
1.4
—
—
—
0
0
518
3008
3.28
51.37
9.5
5.3
0.63
0.59
e9/l
3.05
485
2578
572
3523
3.54
51.33
19.1
8.8
4.40
4.09
e9/l
2.48
543
3087
519
3019
3.28
51.28
9.5
5.3
0.04
0.04
e9/l
0.01
485
2595
497
2839
3.18
50.30
10.6
5.9
8.88
8.77
%
0.28
484
2642
522
3074
3.24
49.92
10.0
5.4
1.57
1.91
e9/l
6.32
492
2699
495
2829
3.16
49.89
10.2
5.6
2.39
2.85
%
4.62
481
2627
501
2893
3.16
49.38
10.3
5.7
22.59
27.11
%
15.90
489
2694
119
274
4.97
49.34
2.2
1.9
3.37
2.54
ug/l
0.16
111
241
526
3124
3.23
49.30
9.9
5.6
0.17
0.19
e9/l
2.01
493
2725
78
127
6.73
46.79
3.4
2.5
15.76
15.73
%
0.01
38
66
488
2848
3.00
45.82
9.8
5.5
61.72
57.66
%
9.58
474
2654
165
522
3.76
44.65
4.5
4.1
1.22
0.87
%
0.98
98
191
161
501
3.81
44.64
4.5
4.1
—
—
—
0
0
42
32
13.84
44.57
1.7
1.7
39.74
38.52
%
0.11
42
32
153
473
3.80
42.71
4.5
4.0
1.06
0.53
%
1.85
85
162
147
468
3.66
39.08
4.4
4.1
0.06
0.71
%
0.50
78
137
527
3365
2.86
38.97
12.1
6.0
9.37
11.37
umol/l
6.11
510
3181
151
491
3.59
38.86
4.5
4.2
0.14
0.11
%
0.24
84
161
62
100
6.66
37.40
2.2
2.9
—
—
—
0
0
507
3267
2.67
35.16
10.3
6.4
1.21
1.21
mmol/l
0.10
366
2769
478
3011
2.59
34.48
9.3
5.5
1.21
1.21
mmol/l
0.25
461
2714
53
81
6.96
33.58
2.6
2.0
89.18
89.46
%
0.13
53
81
427
2676
2.36
29.28
23.3
9.6
0.00
0.00
e9/l
0.44
380
2196
36
13
28.99
26.90
1.7
1.7
—
—
—
0
0
253
1320
2.38
25.81
3.2
3.0
507.48
538.28
mosm/kgh2o
1.67
221
1133
366
2263
2.19
24.48
4.7
3.5
2.35
2.35
mmol/l
0.21
340
1959
60
143
4.47
23.46
2.7
2.1
126.70
126.65
g/l
0.01
44
108
252
1375
2.25
22.63
3.2
2.6
5.71
5.80
e6/l
0.03
230
1242
66
178
3.97
21.91
1.5
1.3
—
—
—
0
0
115
440
2.90
21.90
4.5
2.8
9.71
10.68
g/l
1.09
106
399
164
755
2.50
21.63
7.6
6.9
1.57
1.28
mmol/l
0.47
141
602
49
107
4.83
21.30
1.7
1.3
—
—
—
0
0
36
59
6.36
21.28
1.4
1.5
—
—
—
0
0
454
3159
2.09
21.15
22.7
16.0
1.20
1.29
inr
1.90
198
874
163
757
2.47
21.05
7.7
6.9
5.03
5.10
kpa
0.31
157
730
163
758
2.47
20.98
7.7
6.9
10.58
11.91
kpa
3.59
158
733
116
457
2.82
20.88
4.8
4.2
—
—
—
0
0
190
948
2.34
20.88
2.1
2.0
—
—
—
0
0
290
1723
2.11
20.60
3.7
3.2
—
—
—
0
0
296
1784
2.08
20.13
3.6
3.3
0.33
0.48
e6/l
1.09
255
1364
420
2873
2.04
20.11
6.5
4.5
33.02
35.13
g/l
12.05
398
2671
318
1973
2.05
19.94
3.7
2.4
54.64
102.65
u/l
0.62
295
1817
35
60
6.07
19.78
1.3
1.1
—
—
—
0
0
49
115
4.49
19.51
2.9
2.6
—
—
—
0
0
503
3729
2.04
18.54
8.4
4.5
6.68
6.73
mmol/l
0.25
485
3511
143
662
2.43
18.41
1.7
1.6
—
—
—
0
0
32
55
6.03
18.04
1.1
1.1
—
—
—
0
0
303
1942
1.93
16.54
3.9
3.4
33.09
108.68
e6/l
1.40
260
1509
227
1325
2.02
16.20
2.6
1.6
1.57
1.26
mg/l
0.73
183
1034
603
4884
2.15
16.08
18.0
7.4
80.76
79.02
u/l
0.47
596
4549
161
831
2.19
15.89
6.6
4.9
1.07
1.03
mmol/l
1.10
147
756
89
351
2.74
15.85
2.6
1.6
1.26
1.52
g/l
0.32
80
316
321
2136
1.87
15.32
4.2
3.0
1335.40
1466.06
ng/l
0.34
297
1843
122
570
2.36
15.23
1.6
1.5
—
—
—
0
0
168
899
2.12
15.05
2.8
2.4
21.57
21.71
%
0.04
141
766
114
522
2.39
14.87
1.6
1.4
—
—
—
0
0
173
940
2.09
14.86
2.7
2.4
2.30
2.31
g/l
0.09
160
868
31
65
4.93
14.12
1.1
1.0
—
—
—
0
0
183
1033
2.02
14.09
2.8
2.4
12.16
12.43
umol/l
0.19
170
958
147
765
2.14
14.08
1.4
1.3
185.95
520.68
titre
5.40
37
176
251
1587
1.87
13.75
4.7
3.7
—
—
—
0
0
83
340
2.62
13.68
1.3
1.3
—
—
—
0
0
364
2581
1.79
13.64
5.8
3.9
43.68
49.43
ng/l
0.13
300
1916
248
1567
1.87
13.58
13.6
6.4
—
—
—
0
0
120
589
2.23
13.25
3.9
2.6
65.22
66.44
g/l
0.95
107
529
115
556
2.26
13.17
10.4
6.5
10.74
10.19
mmol/l
0.30
110
529
176
1012
1.96
12.72
2.7
1.9
30.69
29.55
s
1.53
168
973
324
2256
1.76
12.64
4.5
3.9
53.91
112.28
e6/l
1.00
275
1633
254
1657
1.80
12.32
5.4
4.3
0.00
0.00
estimate
-0.00
144
544
280
1889
1.76
12.06
6.4
3.1
35.30
31.89
u/l
0.50
268
1790
91
419
2.33
11.64
3.6
3.3
7.44
7.41
ph
1.50
31
49
515
4190
1.71
10.58
6.3
4.7
2250.92
3258.13
e6/l
0.20
12
71
100
498
2.16
10.57
3.4
2.3
—
—
—
0
0
75
337
2.36
10.13
1.3
1.2
483.53
256.32
u/ml
0.48
68
298
137
780
1.92
10.01
3.7
2.5
1.77
1.82
%
0.23
125
692
72
323
2.36
9.76
3.1
2.9
4.15
4.43
pmol/l
1.31
61
275
34
103
3.41
9.54
1.8
2.3
—
—
—
0
0
110
591
2.01
9.48
4.4
3.0
279.62
217.80
ng/l
0.55
102
547
30
84
3.68
9.46
1.3
1.5
—
—
—
0
0
547
4588
1.69
9.36
6.8
4.2
21.32
13.52
mm/h
14.78
522
4189
132
759
1.89
9.32
1.6
1.4
—
—
—
0
0
27
71
3.91
9.30
1.7
1.3
—
—
—
0
0
110
597
1.99
9.21
3.9
3.4
2.62
1.92
mmol/l
1.23
93
490
393
3049
1.60
9.13
5.0
4.0
0.00
0.01
estimate
0.50
145
551
29
82
3.64
9.03
1.3
1.3
78.40
107.50
u/ml
—
5
12
388
3008
1.59
8.99
6.4
5.4
0.00
0.00
estimate
-0.00
149
566
31
92
3.47
8.99
1.4
1.3
—
—
—
0
0
72
335
2.27
8.97
10.9
9.2
—
—
—
0
0
95
494
2.06
8.94
1.9
1.5
—
—
—
0
0
98
517
2.03
8.87
9.6
7.8
—
—
—
0
0
30
89
3.47
8.71
1.9
2.1
30.40
31.92
pg
0.88
30
89
385
3004
1.57
8.51
5.1
4.0
0.00
0.00
estimate
0.50
157
608
18
38
4.83
8.15
2.6
3.3
43.91
39.90
%
0.35
11
24
88
461
2.03
8.11
1.5
1.4
—
—
—
0
0
105
587
1.92
8.03
3.1
2.7
68.04
70.76
e9/l
0.40
88
457
60
274
2.29
7.82
4.9
4.0
—
—
—
0
0
40
152
2.72
7.67
4.1
3.7
—
—
—
0
0
196
1330
1.64
7.65
3.9
3.0
2.49
2.46
mmol/l
3.14
178
1165
336
2591
1.53
7.52
2.8
2.2
81.70
79.16
nmol/l
0.99
310
2269
325
2491
1.53
7.46
2.3
2.2
—
—
—
0
0
125
755
1.79
7.46
3.1
3.9
6.73
30.44
ug/l
1.41
103
628
509
4299
1.56
7.43
6.4
4.5
—
—
—
0
0
286
2153
1.53
7.03
4.4
3.2
—
—
—
0
0
64
315
2.13
6.96
1.5
1.3
—
—
—
0
0
362
2885
1.49
6.66
3.0
2.6
—
—
—
0
0
30
110
2.80
6.18
1.7
1.6
—
—
—
0
0
45
202
2.31
6.14
5.7
5.7
1.44
1.34
mmol/l
0.36
40
179
26
89
2.99
6.05
1.2
1.2
268.76
330.50
u/ml
0.35
17
50
26
90
2.96
5.94
1.1
1.1
—
—
—
0
0
34
138
2.53
5.77
1.3
1.2
—
—
—
0
0
101
617
1.73
5.76
2.1
2.1
0.21
0.21
g/l
0.59
96
578
45
211
2.20
5.56
5.0
3.3
105.84
86.78
mg/l
0.17
25
174
45
212
2.19
5.50
5.0
3.3
60.39
46.40
mg/l
0.24
25
175
23
78
3.01
5.45
1.4
1.3
—
—
—
0
0
16
33
4.93
5.45
2.7
4.5
7.44
7.42
ph
—
11
8
315
2518
1.43
5.33
3.5
2.8
188.77
130.69
ug/l
2.93
295
2282
197
1440
1.50
5.32
1.9
1.7
495.31
4295973.09
pmol/l
0.50
149
1164
200
1471
1.49
5.23
1.5
1.3
—
—
—
0
0
215
1605
1.47
5.21
3.6
2.7
5626.64
7209.10
umol/l
0.20
188
1373
13
23
5.73
5.08
1.0
1.0
—
—
—
0
0
34
148
2.36
5.01
3.0
2.9
1.70
1.71
mg/l
0.01
29
131
31
131
2.42
4.87
1.3
1.2
—
—
—
0
0
254
1979
1.43
4.85
2.4
2.1
139.69
202.90
u/l
1.63
242
1855
12
22
5.52
4.61
1.1
1.0
—
—
—
0
0
27
110
2.51
4.59
4.4
2.6
—
—
—
0
0
217
1662
1.43
4.51
2.8
2.2
3.46
3.12
mg/l
1.11
194
1392
501
4425
1.39
4.35
6.4
4.1
—
—
—
0
0
33
152
2.22
4.30
1.9
1.7
—
—
—
0
0
429
3699
1.37
4.30
4.1
3.0
71.77
50.09
u/l
2.14
385
3388
28
120
2.38
4.29
1.5
1.3
54.23
64.68
mmol/l
0.77
22
101
106
710
1.57
4.23
1.8
1.7
—
—
—
0
0
14
35
4.06
4.11
2.7
3.5
—
—
—
0
0
20
75
2.71
4.02
1.4
1.3
38750.08
123955.91
e6/l
0.50
13
43
102
686
1.56
4.00
3.7
2.7
8.00
7.93
umol/l
0.01
80
598
115
798
1.52
3.91
1.3
1.3
—
—
—
0
0
14
44
3.22
3.79
1.4
1.2
2.13
2.84
g/l
—
8
33
14
44
3.22
3.79
1.4
1.2
0.45
0.38
g/l
—
8
32
14
44
3.22
3.79
1.4
1.2
4.86
6.85
g/l
—
8
33
564
6082
0.72
3.77
5.0
5.3
2.70
2.68
mmol/l
0.16
487
5517
22
90
2.49
3.74
1.7
1.5
295.59
277.96
mu/l
0.13
22
82
24
103
2.37
3.70
1.2
1.3
148.51
266.12
miu/ml
—
7
46
7
9
7.84
3.56
1.3
1.3
—
—
—
0
0
524
5702
0.74
3.56
4.1
4.2
1.33
1.26
mmol/l
1.28
447
5115
14
46
3.08
3.54
1.4
1.2
—
—
—
0
0
16
57
2.85
3.54
2.2
1.7
2.50
2.23
u/field
—
8
22
35
179
2.00
3.54
3.8
3.1
—
—
—
0
0
13
37
3.56
3.41
1.4
1.2
—
—
—
0
0
29
141
2.10
3.36
1.3
1.1
153.33
71.82
titre
—
6
11
552
5943
0.74
3.31
4.5
4.7
4.64
4.60
mmol/l
0.30
478
5428
167
1285
1.38
3.28
5.5
4.0
392.68
311.56
ng/l
0.12
146
1046
20
84
2.42
3.25
1.4
1.3
1254.50
1334.91
e6/l
0.07
14
56
548
5899
0.74
3.20
4.4
4.7
1.48
1.50
mmol/l
0.31
474
5342
19
80
2.41
3.08
1.6
1.6
0.42
0.86
g/l
1.52
12
63
241
1980
1.32
3.05
3.0
2.5
—
—
—
0
0
8
16
5.04
3.05
1.3
1.3
—
—
—
0
0
12
36
3.37
3.03
5.6
3.2
—
—
—
0
0
52
318
1.68
3.02
2.1
1.8
1.59
1.57
g/l
0.08
40
280
17
69
2.50
2.97
1.6
1.3
—
—
—
0
0
20
88
2.31
2.96
1.2
1.0
—
—
—
0
0
557
5958
0.75
2.87
5.3
4.9
6.07
6.01
mmol/l
0.47
489
5348
144
1105
1.37
2.86
2.1
1.4
2.67
2.56
g/l
0.22
103
629
16
65
2.49
2.80
3.6
1.8
25.63
121.00
u/l
—
7
17
7
14
5.04
2.73
1.1
1.6
—
—
—
0
0
509
4649
1.29
2.72
5.3
4.0
15.21
14.99
pmol/l
0.92
456
4154
12
40
3.03
2.70
1.2
1.2
5.08
0.91
u/ml
—
7
25
8
19
4.24
2.68
1.3
1.4
—
—
—
0
0
17
73
2.36
2.66
5.4
3.9
—
—
—
0
0
80
564
1.47
2.55
2.9
2.4
38.11
34.20
u/l
0.29
70
473
133
1026
1.36
2.55
1.3
1.3
37.61
36.61
iu/ml
0.04
51
327
15
62
2.45
2.55
1.3
1.2
—
—
—
0
0
636
6012
1.36
2.50
36.0
15.3
26.11
24.80
mg/l
0.49
603
4816
14
309
0.44
2.48
1.1
1.4
—
—
—
0
0
168
1348
1.32
2.47
1.9
1.7
1292.54
1199.56
nmol/l
0.50
112
995
13
51
2.58
2.45
1.9
2.5
898.20
587.56
ml
—
5
32
9
27
3.36
2.40
1.2
1.3
2.89
3.99
%
—
9
20
220
1840
1.28
2.35
3.5
3.1
—
—
—
0
0
239
2020
1.27
2.35
5.0
4.1
—
—
—
0
0
8
23
3.50
2.27
2.4
1.5
—
—
—
0
0
14
60
2.36
2.23
4.9
2.9
—
—
—
0
0
5
9
5.58
2.21
1.2
1.2
—
—
—
0
0
5
9
5.58
2.21
3.6
3.6
—
—
—
0
0
5
9
5.58
2.21
1.0
1.0
—
—
—
0
0
124
976
1.32
2.09
1.2
1.3
43.52
12.75
u/ml
1.16
32
356
6
15
4.02
2.04
1.0
1.0
—
—
—
0
0
6
15
4.02
2.04
1.0
1.0
—
—
—
0
0
6
15
4.02
2.04
1.0
1.0
—
—
—
0
0
87
651
1.38
2.03
2.0
2.1
186.70
138.92
ug/g
0.44
65
499
32
195
1.67
1.96
1.2
1.5
274.81
280.81
ug/g
0.05
21
117
10
39
2.58
1.94
2.5
3.3
—
—
—
0
0
8
27
2.98
1.94
1.0
1.4
—
—
—
0
0
5
12
4.19
1.82
1.4
1.4
2.40
2.80
%
—
5
5
22
123
1.81
1.81
1.4
1.2
77.35
32.65
u/l
0.53
17
106
72
533
1.39
1.81
3.8
3.5
89.60
83.73
ng/l
0.27
58
460
8
29
2.78
1.79
3.0
2.7
1073.62
1335.38
u/ml
—
8
29
11
47
2.36
1.78
1.2
1.2
—
—
—
0
0
26
155
1.70
1.74
1.3
1.2
—
760.00
titre
—
0
6
111
887
1.29
1.69
1.3
1.2
—
—
—
0
0
19
104
1.85
1.68
1.8
1.5
—
—
—
0
0
8
31
2.60
1.66
1.3
1.3
80.75
65.40
%
—
8
20
10
42
2.40
1.62
1.1
1.1
—
—
—
0
0
12
56
2.16
1.61
1.0
1.2
—
—
—
0
0
10
43
2.34
1.59
1.4
1.2
—
—
—
0
0
15
78
1.94
1.55
1.1
1.1
1.45
1.59
g/l
0.97
15
68
25
153
1.66
1.55
1.6
2.5
—
—
—
0
0
8
33
2.44
1.54
1.1
1.2
—
—
—
0
0
6
21
2.87
1.51
3.0
2.0
—
—
—
0
0
10
45
2.24
1.47
2.8
2.4
—
—
—
0
0
542
5691
0.83
1.46
6.3
6.2
41.40
40.30
mmol/mol
1.84
479
5205
88
1096
0.78
1.43
3.0
3.1
0.87
0.79
ug/l
0.30
62
742
43
310
1.41
1.31
4.1
3.3
—
—
—
0
0
6
25
2.41
1.24
1.3
1.2
4.92
33.61
%
—
6
20
48
357
1.37
1.23
2.5
2.5
—
—
—
0
0
10
49
2.05
1.22
1.5
1.1
—
—
—
0
0
14
237
0.58
1.20
1.5
1.5
—
—
—
0
0
85
691
1.26
1.17
1.4
1.3
—
—
—
0
0
10
50
2.01
1.17
1.2
1.5
39.49
33.90
u/l
—
10
41
8
39
2.06
1.15
1.3
2.2
—
—
—
0
0
168
1910
0.85
1.14
4.8
5.4
3.56
3.23
ug/l
0.11
142
1684
14
80
1.76
1.13
1.8
1.7
46.89
64.74
%
—
9
54
28
193
1.47
1.10
1.5
1.4
0.24
0.23
g/l
0.26
28
182
7
31
2.27
1.10
1.0
1.0
—
9.88
—
0
9
14
81
1.74
1.09
1.1
1.1
—
—
—
0
0
129
1112
1.19
1.03
3.3
2.9
0.69
1.12
e6/l
1.90
79
638
9
47
1.93
1.02
1.2
1.1
—
—
—
0
0
37
274
1.37
1.01
3.2
3.4
299.66
1462.92
u/ml
0.93
29
237
37
275
1.36
0.99
2.1
2.8
—
—
—
0
0
27
190
1.44
0.98
1.2
1.2
—
—
—
0
0
10
174
0.57
0.97
1.2
1.1
—
—
—
0
0
641
6574
0.84
0.97
48.8
22.8
4.19
4.42
e12/l
22.67
632
6364
641
6573
0.84
0.96
48.6
22.7
30.36
30.36
pg
0.00
635
6453
641
6572
0.84
0.95
48.7
22.8
92.30
91.48
fl
4.20
635
6453
13
209
0.62
0.94
1.8
1.6
—
—
—
0
0
641
6571
0.84
0.94
49.5
22.9
38.01
39.59
%
8.55
598
6084
641
6571
0.84
0.94
49.1
22.8
256.34
246.11
e9/l
3.12
632
6385
6
27
2.23
0.93
2.3
1.9
37.32
53.45
ug/l
—
6
27
6
28
2.15
0.91
2.7
3.8
—
—
—
0
0
6
28
2.15
0.91
1.3
1.3
—
—
—
0
0
40
306
1.32
0.91
1.3
1.2
—
—
—
0
0
11
63
1.76
0.90
2.1
2.2
—
—
—
0
0
19
127
1.51
0.89
1.6
1.7
—
—
—
0
0
54
668
0.79
0.88
5.3
4.1
—
—
—
0
0
642
6573
0.85
0.87
48.7
22.8
7.23
6.71
e9/l
6.56
633
6365
8
44
1.83
0.86
1.3
1.3
—
—
—
0
0
71
592
1.22
0.82
1.5
1.6
—
—
—
0
0
0
24
0.00
0.79
0.0
2.4
—
—
—
0
0
13
197
0.65
0.76
1.5
1.8
—
—
—
0
0
167
1512
1.13
0.73
2.9
2.4
—
—
—
0
0
117
1040
1.15
0.67
3.6
3.1
1.97
2.39
e6/l
0.31
69
568
7
44
1.60
0.65
1.3
1.6
—
—
—
0
0
49
406
1.22
0.64
4.2
3.2
4.54
5.31
e9/l
0.41
40
304
8
49
1.64
0.62
1.3
1.1
—
—
—
0
0
10
64
1.57
0.58
3.7
2.4
0.33
1.36
g/24h
—
5
30
180
1661
1.11
0.58
1.6
1.6
20.13
21.32
nmol/l
0.50
158
1396
157
1709
0.90
0.57
1.6
1.6
1.49
1.34
mmol/l
1.38
114
1418
9
62
1.46
0.53
1.0
1.1
—
—
—
0
0
6
39
1.54
0.53
1.5
1.3
—
—
—
0
0
9
63
1.43
0.52
1.0
1.1
—
—
—
0
0
21
161
1.31
0.52
2.3
2.4
54.22
79.07
ug/min
0.39
11
97
61
529
1.17
0.51
4.5
3.5
—
—
—
0
0
7
106
0.66
0.49
1.6
1.9
33.14
43.88
nmol/l
—
7
98
187
2000
0.91
0.49
3.2
3.2
787.41
264.36
mg/l
0.48
111
1238
29
354
0.81
0.48
3.7
2.8
0.03
0.27
e6/l
3.82
29
344
7
51
1.38
0.44
1.0
1.1
—
—
—
0
0
199
2108
0.92
0.42
3.9
3.7
7.78
7.47
mg/mmol
0.04
108
1274
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
9
67
1.35
0.38
1.7
1.2
—
—
—
0
0
5
37
1.35
0.37
4.2
2.7
13.52
13.32
%
—
5
37
193
2036
0.93
0.36
3.2
3.1
6.20
7.01
mmol/l
2.17
145
1681
38
328
1.17
0.36
2.3
2.2
9.32
12.75
nmol/l
2.16
32
282
11
81
1.36
0.36
1.0
1.1
—
—
—
0
0
6
42
1.43
0.35
1.0
1.0
377.00
292.23
mg/l
—
6
35
6
45
1.34
0.34
2.3
4.0
—
40.34
u/ml
—
0
14
13
100
1.31
0.33
1.2
1.1
—
—
—
0
0
22
182
1.22
0.33
1.1
1.1
—
—
—
0
0
6
46
1.31
0.33
4.7
1.4
—
—
—
0
0
40
352
1.14
0.31
1.3
1.2
142.36
150.36
iu/ml
—
9
134
7
52
1.35
0.31
1.0
1.6
13.19
10.27
%
—
7
52
16
194
0.82
0.28
8.2
10.3
—
—
—
0
0
271
2798
0.95
0.26
2.0
2.1
92.63
94.43
pmol/l
0.27
139
1395
9
73
1.24
0.25
1.2
1.3
—
—
—
0
0
11
87
1.27
0.24
1.1
1.7
—
—
—
0
0
632
6383
0.94
0.23
23.2
10.9
24.83
24.65
u/l
0.13
625
6131
5
39
1.28
0.23
1.0
1.1
—
1.20
—
0
6
0
11
0.00
0.21
0.0
1.0
—
1.81
—
0
5
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
7.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
6
49
1.23
0.20
1.2
1.1
—
—
—
0
0
566
5598
1.04
0.18
6.2
4.9
2.17
2.18
mu/l
0.01
508
5022
24
269
0.89
0.18
2.9
1.9
—
—
—
0
0
623
6176
1.05
0.18
32.3
14.8
—
—
—
0
0
39
423
0.92
0.17
4.0
3.0
—
—
—
0
0
5
70
0.71
0.16
1.8
2.3
—
—
—
0
0
11
92
1.20
0.16
1.5
1.1
—
—
—
0
0
6
79
0.76
0.15
2.3
2.1
212.50
220.75
pmol/l
—
6
72
7
86
0.81
0.14
3.6
1.2
—
—
—
0
0
7
87
0.80
0.14
3.6
1.2
—
—
—
0
0
7
87
0.80
0.14
3.6
1.2
—
—
—
0
0
27
246
1.10
0.14
1.3
1.6
—
—
—
0
0
26
241
1.08
0.10
1.1
1.1
—
27.67
titre
—
0
6
25
232
1.08
0.10
4.4
3.0
0.12
0.22
g/l
2.15
15
83
128
1248
1.03
0.09
1.3
1.2
0.54
1.66
u/ml
2.90
27
311
5
47
1.06
0.09
2.4
1.9
—
—
—
0
0
131
1338
0.97
0.08
6.0
4.5
1.02
1.02
kg/l
0.11
20
195
11
98
1.12
0.07
2.4
2.8
—
—
—
0
0
6
74
0.81
0.07
1.0
1.1
—
150.62
—
0
13
6
75
0.80
0.07
1.7
1.3
—
—
—
0
0
7
82
0.85
0.07
3.6
1.2
—
—
—
0
0
7
85
0.82
0.07
3.6
1.2
—
—
—
0
0
17
157
1.08
0.07
1.1
1.1
—
—
—
0
0
10
89
1.13
0.07
1.2
1.1
—
—
—
0
0
45
433
1.04
0.06
1.1
1.2
—
—
—
0
0
11
99
1.11
0.06
2.5
1.4
—
—
—
0
0
18
170
1.06
0.04
3.3
2.7
—
—
—
0
0
39
380
1.03
0.03
1.3
1.3
—
—
—
0
0
13
123
1.06
0.01
1.1
1.2
—
—
—
0
0
18
187
0.96
0.01
6.2
5.0
—
—
—
0
0
33
326
1.01
0.00
1.3
1.3
—
—
—
0
0
634
6344
1.00
0.00
35.8
18.2
4.00
3.98
mmol/l
0.64
622
6156
633
6329
1.00
0.00
35.4
18.1
138.99
139.68
mmol/l
7.97
621
6146
144
1439
1.00
0.00
5.1
4.0
—
—
—
0
0
7
69
1.01
0.00
1.3
1.3
—
—
nmol/l
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.6
—
17.07
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.06
—
0
5
34
340
1.00
-0.00
4.4
3.9
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
36.33
—
0
9
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
63
0.95
-0.00
3.8
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint J10_RESPCONDEXT and mortality.

Females

Parameter HR [95% CI] p-value
J10_RESPCONDEXT 2.553 [2.22, 2.94] < 0.001
Birth year 0.995 [0.99, 1.0] 0.283

During the follow-up period (1.1.1998 — 31.12.2019), 1081 out of 2197 females with J10_RESPCONDEXT died.

Males

Parameter HR [95% CI] p-value
J10_RESPCONDEXT 4.277 [3.44, 5.32] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 953 out of 1460 males with J10_RESPCONDEXT died.

Mortality risk

Mortality risk for people of age

years, who have J10_RESPCONDEXT.

N-year risk Females Males
1 0.267% 0.724%
5 1.56% 4.682%
10 3.869% 11.389%
15 6.993% 21.879%
20 12.541% 33.517%

Relationships between endpoints

↥

Index endpoint: J10_RESPCONDEXT – Respiratory conditions due to other external agents

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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