Respiratory conditions due to other external agents

J10_RESPCONDEXT

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 J70
  • Hospital discharge: ICD-9 508
  • Cause of death: ICD-10 J70
  • Cause of death: ICD-9 508

2 out of 7 registries used, show all original rules.

695

4. Check minimum number of events

None

695

5. Include endpoints

None

695

6. Filter based on genotype QC (FinnGen only)

695

Control definitions (FinnGen only)

Control exclude
J10_EXTERLUNG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
J60-J70
Name in latin
Morbositates respiratoriae ex aliis agentibus externis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5135 2989 2077
Only index persons 3638 2249 1389
Unadjusted period prevalence (%)
Whole population 0.07 0.09 0.06
Only index persons 0.07 0.08 0.05
Median age at first event (years)
Whole population 69.92 70.17 69.46
Only index persons 67.98 67.98 67.97

-FinnGen-

Key figures

All Female Male
Number of individuals 695 402 293
Unadjusted period prevalence (%) 0.13 0.14 0.13
Median age at first event (years) 66.68 63.64 70.84

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
631
Matched controls
6308
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J70.2
ICD-10 Finland
Acute drug-induced interstitial lung disorders
+∞
262.3
233
*
J70.0
ICD-10 Finland
Acute pulmonary manifestations due to radiation
+∞
251.3
224
*
H02AB06
ATC
prednisolone; systemic
7.0
102.5
500
2217
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
17.5
97.4
160
120
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
6.9
71.3
203
404
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.6
70.3
432
2015
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.8
67.1
171
287
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.6
64.7
306
1075
H02AB02
ATC
dexamethasone; systemic
6.3
61.9
188
398
A03FA01
ATC
metoclopramide; systemic, rectal
4.7
61.8
270
866
TGC00
NOMESCO Finland
Bronchial lavation
21.7
58.6
87
46
J70.4
ICD-10 Finland
Drug-induced interstitial lung disorders, unspecified
+∞
57.1
54
*
XX3DW
NOMESCO Finland
Time consuming IT work
6.4
57.0
169
343
A04AA02
ATC
granisetron; systemic, transdermal
7.8
52.4
130
203
J70.3
ICD-10 Finland
Chronic drug-induced interstitial lung disorders
+∞
51.8
49
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
10.6
49.4
100
110
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
6.6
48.1
135
250
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
13.3
46.8
84
72
115
Kela drug reimbursment
Breast cancer
5.8
45.7
143
303
J70.1
ICD-10 Finland
Chronic and other pulmonary manifestations due to radiation
+∞
40.0
38
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
6.8
39.1
105
180
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.1
37.6
288
1332
JN4BD
NOMESCO Finland
Extensive body CT
4.5
37.6
150
408
GD1AD
NOMESCO Finland
Thorax CT examination
8.6
37.3
84
110
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
5.3
34.2
114
254
WF049
NOMESCO Finland
Radiotherapy of metastasis
9.7
34.1
71
81
JN4AD
NOMESCO Finland
Body CT examination
5.3
34.0
113
251
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
11.9
33.8
63
58
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.7
33.6
81
118
L02BG04
ATC
letrozole; oral
5.8
33.3
101
201
130
Kela drug reimbursment
Malignant tumour
4.7
33.1
123
308
J01MA12
ATC
levofloxacin; systemic
3.3
32.2
200
779
ZX080
NOMESCO Finland
Image guided radiotherapy
12.7
32.0
58
50
N02AA05
ATC
oxycodone; systemic
3.5
31.8
173
607
A02BC02
ATC
pantoprazole; systemic
2.9
31.8
479
3266
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
30.3
307
1631
HA1AA
NOMESCO Finland
X-ray mammography
4.7
30.2
112
278
ZX070
NOMESCO Finland
Intensity modified radiotherapy
11.7
29.9
56
52
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.1
29.8
76
120
R50.9
ICD-10 Finland
Fever, unspecified
3.6
29.3
151
505
R06.0
ICD-10 Finland
Dyspnoea
2.8
28.8
237
1101
WZC30
NOMESCO Finland
Teaching
3.7
28.5
142
461
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
9.0
28.2
61
74
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
6.0
27.8
80
148
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
18.2
26.5
41
24
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.6
25.4
128
417
J70.9
ICD-10 Finland
Respiratory conditions due to unspecified external agent
+∞
25.2
24
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
12.3
24.8
45
39
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.8
24.8
88
207
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.8
24.7
87
203
C03CA01
ATC
furosemide; systemic
2.4
23.6
280
1558
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.3
23.2
74
155
WF003
NOMESCO Finland
Adjuvant radiotherapy
6.6
23.0
61
101
L03AA14
ATC
lipegfilgrastim; parenteral
10.4
22.9
45
46
A04AA55
ATC
palonosetron, combinations; systemic
8.1
22.8
52
69
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
24.0
22.8
32
14
L03AA13
ATC
pegfilgrastim; parenteral
6.1
22.4
63
113
B01AB10
ATC
tinzaparin; parenteral
4.4
22.0
84
212
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
5.9
21.6
62
114
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
6.6
21.6
57
94
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
4.4
21.4
81
203
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
21.4
189
887
PJA12
NOMESCO Finland
Sentinel node biopsy
3.8
21.3
96
282
JN4CD
NOMESCO Finland
Very extensive body CT
5.8
20.4
59
110
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
19.6
20.1
30
16
Z51.5
ICD-10 Finland
Palliative care
4.1
19.9
81
217
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
19.8
123
461
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
8.2
19.6
44
57
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
6.1
19.5
54
95
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
4.5
19.1
70
170
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
5.0
19.1
63
137
A04AA01
ATC
ondansetron; systemic, rectal
4.3
18.3
70
177
HAB40
NOMESCO Finland
Wedge excision of mammary gland
4.3
18.0
69
175
WF004
NOMESCO Finland
Palliative radiotherapy
8.9
17.9
38
45
TGD00
NOMESCO Finland
Needle biopsy of lung
37.9
17.7
22
6
XW000
NOMESCO Finland
Bone marrow biopsy
5.1
17.6
56
117
WF002
NOMESCO Finland
Radical radiotherapy
4.5
17.2
62
148
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
17.1
140
619
J01MA14
ATC
moxifloxacin; systemic
3.4
16.9
87
284
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
7.4
16.8
40
57
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.2
16.8
93
319
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
10.5
16.6
32
32
HA1DG
NOMESCO Finland
Very extensive MRI examination of mammary gland with high intensity magnet
23.8
16.5
23
10
NK6AN
NOMESCO Finland
Total body bone isotope imaging
6.1
16.2
44
76
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.0
16.0
66
179
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.9
15.9
105
405
C01BD01
ATC
amiodarone; systemic
5.6
15.4
45
85
M05BX04
ATC
denosumab; parenteral
3.9
15.2
65
182
WW500
NOMESCO Finland
Blood transfusion
4.8
15.2
51
113
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
20.7
15.2
22
11
A02BC01
ATC
omeprazole; systemic
2.1
15.0
219
1273
HAC20
NOMESCO Finland
Total mastectomy
4.1
14.7
59
156
A04AD12
ATC
aprepitant; systemic
7.0
14.7
36
54
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
4.4
14.4
53
129
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
8.5
14.4
31
38
L03AA02
ATC
filgrastim; parenteral
6.5
14.3
37
60
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
14.3
309
2085
B01AB05
ATC
enoxaparin; parenteral
2.0
14.3
231
1393
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
4.8
13.9
47
105
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.2
13.9
169
903
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
4.5
13.7
49
116
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
6.8
13.7
34
52
N03AX16
ATC
pregabalin; oral
2.1
13.7
178
980
5088A
ICD-9 Finland
Respiratory conditions due to other and unspecified external agents, Respiratory conditions due to other specified external agents[MORBI ORGANORUM RESPIRATIONIS E PHARMACO]
+∞
13.6
13
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
13.5
97
394
C50.99
ICD-10 Finland
Breast, unspecified
5.3
13.4
41
82
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
8.4
13.4
29
36
L02BA01
ATC
tamoxifen; oral
4.5
13.3
47
110
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.1
13.3
75
260
C07AB07
ATC
bisoprolol; oral
1.9
13.3
346
2473
L02BG06
ATC
exemestane; oral
8.2
13.2
29
37
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
12.5
13.2
23
19
M04AA01
ATC
allopurinol; systemic
2.4
13.1
120
557
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
11.9
12.9
23
20
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
12.6
12.7
22
18
XX1XN
NOMESCO Finland
Other isotope examination
11.3
12.6
23
21
L01CA04
ATC
vinorelbine; systemic
13.5
12.5
21
16
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
13.5
12.5
21
16
L02BG03
ATC
anastrozole; oral
6.7
12.5
31
48
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
7.4
12.4
29
41
I50.9
ICD-10 Finland
Heart failure, unspecified
2.3
12.4
127
621
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
5.8
12.2
34
61
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.0
12.1
49
131
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
7.5
12.1
28
39
N05CF01
ATC
zopiclone; oral
1.9
12.0
242
1562
J70.8
ICD-10 Finland
Respiratory conditions due to other specified external agents
+∞
11.5
11
*
X76
ICPC
Malignant neoplasm breast female
6.2
11.5
30
50
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
7.2
11.4
27
39
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
11.3
81
328
ZX120
NOMESCO Finland
Intravenous
2.6
11.3
86
359
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
9.9
11.3
22
23
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
4.2
11.3
43
109
WX402
NOMESCO Finland
General anaesthesia
2.3
11.3
118
581
NK6AQ
NOMESCO Finland
Whole body bone SPET with low dose CT
35.7
11.3
14
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
9.1
10.8
22
25
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
9.1
10.8
22
25
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
10.8
182
1094
N02AX02
ATC
tramadol; systemic, rectal
1.8
10.8
292
2061
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.4
10.8
92
411
ED1AA
NOMESCO Finland
Mandipular X-ray examination
61.0
10.7
12
*
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
4.4
10.6
38
91
R03AC02
ATC
salbutamol; inhalant
1.8
10.6
322
2348
N02AA01
ATC
morphine; systemic, rectal
8.7
10.6
22
26
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
6.7
10.6
26
40
HA4AT
NOMESCO Finland
Labeling mammary gland pathology with ultrasound guidance
4.9
10.4
33
70
R05
ICD-10 Finland
Cough
2.1
10.3
137
749
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
19.2
10.3
15
8
J01CA04
ATC
amoxicillin; systemic
1.9
10.3
484
4031
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.7
10.2
34
76
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
5.3
10.1
30
59
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
40.7
10.0
12
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
6.1
9.9
26
44
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
12.4
9.9
17
14
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.0
9.8
56
196
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
9.8
144
819
XG410
NOMESCO Finland
Flow-volume spirometry
3.9
9.8
39
104
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.5
9.7
82
361
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
8.0
9.7
21
27
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
9.7
76
322
N02BE01
ATC
paracetamol; systemic, rectal
2.0
9.6
537
4678
A07EC01
ATC
sulfasalazine; oral, rectal
2.8
9.5
63
244
ZX095
NOMESCO Finland
Combined chemoradiotherapy
12.6
9.4
16
13
5088X
ICD-9 Finland
Respiratory conditions due to other and unspecified external agents, Respiratory conditions due to other specified external agents[MORBI ORGANORUM RESP CAUSA EXT ALIA DEFINITA]
+∞
9.4
9
*
L04AX01
ATC
azathioprine; systemic
3.9
9.4
38
103
M05BA04
ATC
alendronic acid; oral
2.4
9.4
78
344
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
9.1
117
628
C50.29
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland, other or undeterminated histology
15.9
9.1
14
9
XX9AQ
NOMESCO Finland
Supplementary SPECT-CT or additional scan
37.2
9.0
11
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.5
9.0
70
298
R03BB04
ATC
tiotropium bromide; inhalant
2.3
8.9
85
402
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
8.8
200
1312
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
6.5
8.8
22
35
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
9.7
8.8
17
18
A06AD11
ATC
lactulose; oral
2.0
8.8
117
637
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.8
8.7
36
100
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
6.3
8.7
22
36
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.9
8.7
23
40
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
5.9
8.7
23
40
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
8.6
220
1496
HAB99
NOMESCO Finland
Other partial excision of mammary gland
4.9
8.6
27
57
JN6AD
NOMESCO Finland
CT of torso and neck
8.4
8.6
18
22
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
4.7
8.6
28
62
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
8.5
84
401
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
8.4
79
367
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
8.0
8.4
18
23
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
8.0
8.4
18
23
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.9
8.4
50
182
NK6BQ
NOMESCO Finland
Whole body extensive bone SPET with low dose CT
13.0
8.4
14
11
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
10.9
8.3
15
14
J01DB01
ATC
cefalexin; oral
1.7
8.3
483
4116
R04.2
ICD-10 Finland
Haemoptysis
3.6
8.3
36
104
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
8.3
86
422
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.2
8.3
30
74
L04AA13
ATC
leflunomide; oral
4.5
8.2
28
65
C50
ICD-10 Finland
Malignant neoplasm of breast
4.5
8.2
28
65
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
4.8
8.2
26
56
J01MA02
ATC
ciprofloxacin; systemic
1.7
8.1
252
1806
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
17.4
8.1
12
7
R84
ICPC
Malignant neoplasm bronchus/lung
17.4
8.1
12
7
J01FF01
ATC
clindamycin; systemic
1.8
8.1
168
1068
HA3AT
NOMESCO Finland
Pucture of mammary gland cyst with ultrasound examination
10.2
8.1
15
15
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.8
8.0
165
1047
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.8
7.9
51
195
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.7
7.9
51
196
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
4.4
7.8
27
64
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
5.1
7.8
23
46
WX892
NOMESCO Finland
Monitored bed care
2.4
7.8
63
275
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
7.7
274
2026
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.8
7.7
31
85
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
8.2
7.6
16
20
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
8.2
7.6
16
20
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
18.6
7.6
11
6
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
18.6
7.6
11
6
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.3
7.6
22
43
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
7.6
53
213
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
7.5
115
659
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
7.5
36
113
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
6.6
7.5
18
28
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
5.4
7.4
21
40
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
6.1
7.4
19
32
J01AA02
ATC
doxycycline; systemic
1.7
7.3
486
4197
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
7.3
160
1033
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
6.4
7.3
18
29
J96.1
ICD-10 Finland
Chronic respiratory failure
4.2
7.3
26
64
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
15.9
7.2
11
7
C81.9
ICD-10 Finland
Hodgkin lymphoma, unspecified
30.4
7.2
9
*
OAB38
NOMESCO Finland
Psychosocial guidance and counselling
30.4
7.2
9
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
20.3
7.1
10
5
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
7.1
171
1129
J96.0
ICD-10 Finland
Acute respiratory failure
5.4
7.1
20
38
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
12.2
7.1
12
10
A02BC05
ATC
esomeprazole; systemic
1.6
7.1
254
1870
SPAT1263
SPAT
Sampling
1.6
7.1
261
1935
J01DA01
ATC
[U] cefalexin; systemic
1.6
7.1
373
3021
Z31.5
ICD-10 Finland
Genetic counselling
3.4
7.0
32
97
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
7.0
87
460
HAD30
NOMESCO Finland
Reduction mammoplasty with transposition of areola
3.6
7.0
30
87
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
5.3
7.0
20
39
L04AA06
ATC
mycophenolic acid; systemic
5.3
7.0
20
39
B01AA03
ATC
warfarin; systemic
1.7
7.0
154
995
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
4.1
6.8
25
63
WF099
NOMESCO Finland
Other radiotherapy
9.4
6.8
13
14
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
40.5
6.8
8
*
8070/3-C34.1
ICD-O-3
Squamous cell carcinoma, NOS, of upper lobe, lung
16.9
6.8
10
6
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
16.9
6.8
10
6
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.7
6.7
43
165
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
5.3
6.7
19
37
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
6.0
6.6
17
29
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.5
6.6
49
203
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
70.5
6.4
7
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
6.4
92
515
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
6.6
6.4
15
23
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
4.3
6.4
22
53
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
5.3
6.4
18
35
WX722
NOMESCO Finland
PEEP
3.0
6.4
36
126
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
8.3
6.4
13
16
8140/3-C34.3
ICD-O-3
Adenocarcinoma, NOS, of lower lobe, lung
18.2
6.3
9
5
J80
ICD-10 Finland
Adult respiratory distress syndrome
18.2
6.3
9
5
Z85.3
ICD-10 Finland
Personal history of malignant neoplasm of breast
7.1
6.2
14
20
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
6.2
94
535
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
6.4
6.2
15
24
I50.0
ICD-10 Finland
Congestive heart failure
2.1
6.2
65
323
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
7.8
6.1
13
17
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
12.7
6.1
10
8
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
6.1
33
115
C50.22
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,lobular tumor
10.1
6.0
11
11
8070/3-C34.9
ICD-O-3
Squamous cell carcinoma, NOS, of lung, NOS
6.1
6.0
15
25
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
77
84
10.18
65.13
2.4
2.8
—
—
—
0
0
366
1664
3.53
59.02
6.5
4.1
—
—
—
0
0
250
928
3.65
54.77
5.3
3.2
0.8
0.8
mmol/l
0.62
242
854
75
100
8.29
54.04
3.2
2.7
4.4
4.5
e9/l
0.19
75
100
76
105
8.00
53.13
3.7
3.0
61.9
59.3
%
0.66
76
105
170
500
4.18
51.97
7.0
3.5
1.2
1.2
mmol/l
0.01
162
434
382
1888
3.27
51.78
9.2
5.4
—
—
—
0
0
80
121
7.34
51.61
5.1
3.7
2.7
2.6
mmol/l
0.03
65
82
87
145
6.72
51.25
5.2
3.5
7.4
7.4
ph
3.59
80
118
77
115
7.41
50.22
4.0
3.3
—
—
—
0
0
32
12
27.91
46.68
1.8
1.8
—
—
—
0
0
359
1814
3.03
45.02
7.2
3.7
7.4
7.4
ph
1.40
142
339
159
492
3.89
44.77
3.2
2.0
357.6
375.3
nmol/l
0.41
153
442
440
2509
3.05
43.86
10.2
5.5
0.6
0.7
%
2.85
425
2320
106
245
4.93
43.74
2.3
1.9
3.8
2.8
ug/l
0.17
98
216
465
2737
3.11
43.70
9.6
5.3
0.6
0.6
e9/l
2.75
438
2339
466
2753
3.10
43.37
9.6
5.3
0.0
0.0
e9/l
0.10
438
2367
446
2585
3.02
42.73
10.8
5.8
8.8
8.8
%
0.07
434
2402
164
534
3.71
42.70
1.5
1.4
—
—
—
0
0
469
2796
3.08
42.64
10.1
5.4
1.6
1.9
e9/l
5.31
445
2443
512
3213
3.25
42.35
18.7
8.8
4.4
4.1
e9/l
2.55
489
2814
444
2577
3.00
42.24
10.4
5.5
2.3
2.8
%
4.95
431
2385
450
2633
3.01
42.14
10.5
5.7
22.5
27.0
%
14.52
437
2428
472
2848
3.05
41.51
10.0
5.6
0.2
0.2
e9/l
1.78
446
2488
69
116
6.49
40.10
3.4
2.3
16.0
15.8
%
0.11
30
59
437
2595
2.84
38.38
10.0
5.5
61.9
57.8
%
9.48
424
2410
143
465
3.61
36.93
4.5
4.1
—
—
—
0
0
39
37
11.11
36.05
1.9
2.0
0.8
1.1
e9/l
0.99
34
20
246
1118
2.86
35.81
7.4
4.6
—
—
—
0
0
143
475
3.53
35.66
4.4
3.8
1.1
0.9
%
0.60
75
147
132
427
3.58
34.20
4.3
3.9
0.8
0.4
%
1.42
63
105
52
79
7.03
33.17
2.2
2.8
—
—
—
0
0
50
74
7.20
32.66
2.6
2.1
89.2
89.2
%
0.01
50
74
128
423
3.48
31.97
4.2
4.0
0.0
0.9
%
0.52
64
112
132
446
3.42
31.83
4.4
4.0
0.2
0.1
%
0.22
71
133
470
3065
2.65
31.51
12.1
5.9
9.3
11.3
umol/l
5.69
455
2895
458
2984
2.57
30.19
10.2
6.4
1.2
1.2
mmol/l
0.03
327
2499
42
56
7.92
30.01
1.7
1.6
—
—
—
0
0
42
56
7.92
30.01
1.7
1.6
—
—
—
0
0
42
56
7.92
30.01
1.7
1.6
—
—
—
0
0
42
56
7.92
30.01
1.7
1.6
—
—
—
0
0
430
2748
2.48
29.12
9.2
5.5
1.2
1.2
mmol/l
0.09
414
2459
232
1181
2.45
25.35
3.2
2.8
514.4
547.1
mosm/kgh2o
1.56
204
1006
381
2431
2.26
24.16
22.7
9.7
0.0
0.0
e9/l
0.41
341
1994
382
2493
2.18
22.24
15.6
9.6
1.2
1.3
inr
2.69
171
684
46
94
5.17
21.62
1.8
1.3
—
—
—
0
0
106
402
2.93
20.57
4.7
2.8
9.9
10.7
g/l
0.79
97
364
229
1251
2.24
20.51
3.2
2.6
6.0
6.0
e6/l
0.02
210
1103
106
410
2.87
19.82
4.9
4.3
—
—
—
0
0
326
2069
2.08
19.62
4.4
3.4
2.4
2.4
mmol/l
0.00
300
1778
33
54
6.37
19.54
1.5
1.5
—
—
—
0
0
174
873
2.32
18.90
2.1
2.0
—
—
—
0
0
147
690
2.43
18.53
7.2
7.0
1.7
1.3
mmol/l
0.50
126
542
263
1576
2.08
18.14
3.7
3.2
—
—
—
0
0
58
166
3.72
17.71
1.5
1.3
—
—
—
0
0
268
1631
2.05
17.61
3.7
3.3
0.3
0.5
e6/l
1.43
233
1234
29
47
6.40
17.32
1.1
1.1
—
—
—
0
0
49
127
4.08
17.18
2.7
1.9
128.4
127.5
g/l
0.08
34
95
144
692
2.36
17.12
7.4
7.0
5.1
5.1
kpa
0.11
138
669
32
58
5.74
17.10
1.3
1.1
—
—
—
0
0
144
693
2.36
17.06
7.3
7.0
10.5
11.9
kpa
3.68
139
672
128
594
2.42
16.41
1.6
1.6
—
—
—
0
0
376
2621
1.95
16.34
6.4
4.5
32.9
35.0
g/l
10.50
356
2432
108
469
2.54
15.95
1.6
1.5
—
—
—
0
0
281
1790
1.96
15.82
3.7
2.3
54.5
56.9
u/l
0.50
261
1647
209
1200
2.06
15.80
2.7
1.6
1.6
1.3
mg/l
0.58
170
937
114
514
2.46
15.52
1.6
1.5
—
—
—
0
0
83
323
2.78
15.22
2.7
1.6
1.3
1.6
g/l
0.35
75
290
30
58
5.36
14.97
1.1
1.1
—
—
—
0
0
274
1776
1.90
14.30
3.9
3.4
34.5
108.0
e6/l
1.19
237
1379
448
3393
1.90
14.29
8.4
4.6
6.7
6.7
mmol/l
0.43
431
3192
143
739
2.18
14.07
6.2
5.0
1.1
1.0
mmol/l
1.18
131
674
78
307
2.74
13.97
1.3
1.3
—
—
—
0
0
153
817
2.12
13.82
2.8
2.5
20.8
21.7
%
0.32
126
696
158
861
2.08
13.50
2.7
2.4
2.3
2.3
g/l
0.09
145
795
40
107
3.91
13.43
2.9
2.3
—
—
—
0
0
542
4429
2.02
13.11
17.8
7.3
81.2
79.1
u/l
0.53
536
4128
134
698
2.14
12.84
1.4
1.3
189.7
538.0
titre
5.08
35
162
107
509
2.30
12.80
9.8
6.5
10.8
10.1
mmol/l
0.34
102
483
167
945
2.01
12.80
2.8
2.4
11.8
12.4
umol/l
0.42
154
866
331
2340
1.79
12.59
5.7
3.9
45.8
52.0
ng/l
0.13
274
1735
110
538
2.24
12.30
3.8
2.7
64.8
66.4
g/l
1.35
97
481
287
1965
1.78
12.02
4.1
3.1
1337.1
1505.9
ng/l
0.43
263
1694
97
461
2.28
11.59
3.5
2.3
—
—
—
0
0
222
1436
1.80
11.08
13.5
6.3
—
—
—
0
0
292
2062
1.72
10.62
4.5
3.9
56.3
116.2
e6/l
0.91
250
1490
223
1461
1.78
10.57
4.7
3.6
—
—
—
0
0
30
79
3.92
10.31
1.3
1.5
—
—
—
0
0
26
62
4.32
10.17
1.8
1.2
—
—
—
0
0
127
713
1.96
9.75
3.5
2.5
1.8
1.8
%
0.09
115
631
227
1524
1.73
9.73
5.4
4.3
0.0
0.0
estimate
0.00
125
502
81
387
2.24
9.52
3.6
3.2
7.4
7.4
ph
1.75
27
44
153
929
1.83
9.19
2.7
1.9
30.6
29.5
s
1.27
146
891
100
539
2.00
8.58
4.7
3.1
288.6
226.5
ng/l
0.49
92
499
39
139
2.91
8.41
4.2
3.8
—
—
—
0
0
464
3836
1.63
8.23
6.4
4.8
2444.3
3636.7
e6/l
0.22
11
62
28
83
3.47
8.15
1.3
1.3
—
—
—
0
0
27
79
3.52
8.02
1.7
2.0
30.0
31.9
pg
1.13
27
79
84
440
2.03
7.79
2.0
1.5
—
—
—
0
0
81
419
2.06
7.77
1.5
1.4
—
—
—
0
0
65
310
2.21
7.67
1.3
1.2
551.4
264.8
u/ml
0.55
59
272
97
538
1.93
7.64
2.9
2.6
68.5
70.7
e9/l
0.27
81
417
12
18
6.77
7.62
1.0
1.1
—
—
—
0
0
491
4157
1.62
7.51
6.9
4.2
21.4
13.5
mm/h
13.46
468
3783
263
1941
1.57
7.32
4.5
3.3
—
—
—
0
0
115
689
1.80
7.10
1.7
1.4
—
—
—
0
0
353
2794
1.54
7.10
5.0
4.0
0.0
0.0
estimate
0.50
128
510
25
76
3.37
7.03
1.2
1.2
268.8
349.4
u/ml
0.47
17
40
348
2756
1.53
6.92
6.3
5.3
0.0
0.0
estimate
0.00
131
522
11
17
6.56
6.79
1.1
1.1
—
—
—
0
0
59
286
2.16
6.70
1.5
1.3
—
—
—
0
0
95
549
1.85
6.58
3.9
3.4
2.7
1.9
mmol/l
1.29
77
438
53
248
2.23
6.57
4.7
4.0
—
—
—
0
0
25
80
3.20
6.50
1.1
1.1
—
—
—
0
0
344
2743
1.50
6.46
5.1
4.0
0.0
0.0
estimate
0.00
136
524
59
292
2.12
6.36
2.9
2.8
4.1
4.4
pmol/l
1.15
50
248
44
193
2.37
6.33
5.0
3.4
107.1
92.0
mg/l
0.12
24
159
44
194
2.35
6.26
5.0
3.4
60.9
45.1
mg/l
0.26
24
160
85
482
1.87
6.25
8.9
7.8
—
—
—
0
0
176
1222
1.59
6.20
3.6
3.0
2.5
2.5
mmol/l
3.31
161
1073
111
690
1.72
6.01
3.0
3.9
6.6
27.3
ug/l
1.08
91
577
60
306
2.05
5.99
10.4
9.3
—
—
—
0
0
28
101
2.85
5.96
1.7
1.5
—
—
—
0
0
33
131
2.59
5.87
1.2
1.2
—
—
—
0
0
23
75
3.14
5.81
1.4
1.3
—
—
—
0
0
290
2268
1.48
5.80
2.4
2.2
—
—
—
0
0
40
176
2.35
5.73
6.1
5.8
1.4
1.3
mmol/l
0.08
35
158
30
116
2.66
5.62
1.3
1.2
—
—
—
0
0
456
3916
1.48
5.51
6.6
4.5
—
—
—
0
0
13
30
4.40
5.31
2.7
4.7
7.4
7.4
ph
—
8
7
93
573
1.72
5.18
3.8
3.4
—
—
—
0
0
197
1454
1.50
5.14
3.7
2.7
4732.2
7109.7
umol/l
0.32
171
1227
33
143
2.37
4.92
1.9
1.7
—
—
—
0
0
286
2288
1.42
4.84
3.5
2.7
188.4
132.4
ug/l
2.43
268
2070
320
2612
1.42
4.83
5.3
4.0
—
—
—
0
0
504
5521
0.68
4.59
4.9
5.3
2.7
2.7
mmol/l
0.40
433
4999
52
279
1.93
4.54
4.3
3.4
25.3
24.3
mmol/l
1.06
46
254
90
571
1.66
4.50
2.3
2.1
0.2
0.2
g/l
0.71
85
534
176
1303
1.47
4.45
1.9
1.7
502.5
440.3
pmol/l
1.55
133
1050
20
72
2.83
4.32
1.4
1.3
38750.1
123955.9
e6/l
0.50
13
43
12
31
3.92
4.27
1.4
1.3
—
—
—
0
0
198
1515
1.43
4.17
2.8
2.2
3.5
3.1
mg/l
1.06
178
1268
24
99
2.48
4.01
3.6
2.7
—
—
—
0
0
12
33
3.68
3.93
5.6
3.4
—
—
—
0
0
21
82
2.61
3.92
1.7
1.5
303.0
283.9
mu/l
0.13
21
74
494
5389
0.71
3.85
4.4
4.7
4.7
4.6
mmol/l
0.42
426
4913
96
645
1.57
3.81
1.9
1.7
—
—
—
0
0
470
5165
0.72
3.80
3.9
4.1
1.3
1.3
mmol/l
1.48
398
4628
7
8
8.82
3.78
1.3
1.3
—
—
—
0
0
51
290
1.82
3.77
2.1
1.8
1.6
1.5
g/l
0.14
39
255
93
622
1.57
3.77
3.6
2.6
8.3
7.9
umol/l
0.07
71
542
20
78
2.61
3.74
1.2
1.0
—
—
—
0
0
25
109
2.34
3.73
1.5
1.3
57.5
65.6
mmol/l
0.49
19
94
225
1791
1.38
3.70
2.4
2.1
144.8
208.1
u/l
1.37
213
1676
104
719
1.53
3.63
1.4
1.3
—
—
—
0
0
491
5347
0.72
3.62
4.3
4.6
1.5
1.5
mmol/l
0.41
423
4834
29
137
2.17
3.60
2.9
2.9
1.6
1.7
mg/l
0.21
24
123
20
81
2.51
3.49
1.4
1.3
1254.5
1334.9
e6/l
0.07
14
56
452
4027
1.35
3.46
6.3
4.2
—
—
—
0
0
8
14
5.77
3.35
1.3
1.3
—
—
—
0
0
223
1797
1.35
3.34
2.9
2.5
—
—
—
0
0
27
128
2.15
3.34
1.3
1.2
153.3
71.0
titre
—
6
10
499
5401
0.73
3.32
5.3
4.9
6.0
6.0
mmol/l
0.18
435
4842
32
163
2.01
3.29
4.2
3.0
—
—
—
0
0
17
66
2.62
3.23
1.6
1.3
—
—
—
0
0
21
91
2.35
3.20
1.0
1.3
122.5
274.9
miu/ml
—
6
39
171
1331
1.38
3.17
1.6
1.3
—
—
—
0
0
13
44
2.99
3.15
1.9
2.5
898.2
556.8
ml
—
5
26
12
39
3.11
3.10
1.5
1.2
0.4
0.4
g/l
—
7
28
12
39
3.11
3.10
1.2
1.2
5.1
1.0
u/ml
—
7
23
12
39
3.11
3.10
1.5
1.2
2.2
2.9
g/l
—
7
29
12
39
3.11
3.10
1.5
1.2
5.0
7.1
g/l
—
7
29
134
1005
1.41
3.09
2.1
1.4
2.7
2.6
g/l
0.24
96
567
7
12
5.88
3.02
1.1
1.8
—
—
—
0
0
12
41
2.96
2.87
1.5
1.2
—
—
—
0
0
11
286
0.37
2.85
1.1
1.4
—
—
—
0
0
17
71
2.43
2.82
1.6
1.7
0.5
0.9
g/l
1.44
11
55
8
18
4.48
2.80
1.3
1.3
—
—
—
0
0
122
922
1.39
2.69
1.3
1.3
37.3
37.8
iu/ml
0.02
47
293
15
62
2.45
2.55
3.7
1.9
29.8
128.4
u/l
—
6
16
14
56
2.53
2.54
5.0
3.2
—
—
—
0
0
31
173
1.83
2.50
1.1
1.5
285.2
275.2
ug/g
0.09
20
102
9
26
3.49
2.49
1.2
1.3
2.9
4.2
%
—
9
19
154
1225
1.33
2.44
1.9
1.8
1320.5
1204.8
nmol/l
0.62
104
903
5
8
6.29
2.37
3.6
3.6
—
—
—
0
0
81
586
1.43
2.29
1.8
2.1
155.5
145.8
ug/g
0.09
61
445
15
66
2.30
2.26
5.7
3.3
—
—
—
0
0
5
9
5.59
2.21
1.0
1.0
—
—
—
0
0
5
9
5.59
2.21
1.2
1.2
—
—
—
0
0
13
54
2.43
2.21
1.2
1.2
—
—
—
0
0
114
883
1.35
2.16
1.2
1.3
37.3
13.0
u/ml
0.89
31
316
73
991
0.71
2.12
2.6
3.1
0.9
0.8
ug/l
0.36
49
669
67
476
1.45
2.10
4.0
3.4
89.6
83.8
ng/l
0.25
54
409
8
25
3.22
2.10
1.0
1.1
—
—
—
0
0
6
15
4.03
2.04
1.0
1.0
—
—
—
0
0
6
15
4.03
2.04
1.0
1.0
—
—
—
0
0
6
15
4.03
2.04
1.0
1.0
—
—
—
0
0
9
32
2.84
2.00
3.0
3.7
—
—
—
0
0
25
142
1.79
1.95
1.3
1.2
—
760.0
titre
—
0
6
145
1181
1.29
1.93
5.6
4.0
443.5
315.8
ng/l
0.17
127
964
486
5167
0.80
1.89
6.4
6.2
41.3
40.3
mmol/mol
1.30
430
4722
214
1831
1.24
1.88
5.0
4.1
—
—
—
0
0
7
22
3.20
1.88
2.6
1.5
—
—
—
0
0
5
12
4.19
1.82
1.4
1.4
2.4
2.8
%
—
5
5
455
4225
1.22
1.75
5.2
4.0
15.2
15.0
pmol/l
0.60
406
3770
6
18
3.35
1.75
3.0
1.9
—
—
—
0
0
573
5459
1.28
1.73
36.2
15.5
25.9
24.8
mg/l
0.34
543
4383
8
30
2.69
1.73
1.3
1.3
80.8
63.8
%
—
8
19
194
1662
1.23
1.67
3.5
3.1
—
—
—
0
0
46
320
1.47
1.64
2.5
2.4
—
—
—
0
0
12
56
2.16
1.62
1.8
1.7
3.0
2.2
u/field
—
6
22
14
70
2.02
1.60
1.1
1.1
—
—
—
0
0
14
71
1.99
1.55
1.1
1.1
1.5
1.6
g/l
0.53
14
62
100
801
1.29
1.52
1.3
1.2
—
—
—
0
0
11
51
2.18
1.51
1.0
1.2
—
—
—
0
0
146
1721
0.81
1.50
4.6
5.4
3.6
3.2
ug/l
0.12
123
1519
9
38
2.39
1.46
1.3
1.2
—
—
—
0
0
41
288
1.45
1.42
4.1
3.2
—
—
—
0
0
36
247
1.48
1.40
3.2
3.3
309.9
1316.0
u/ml
0.73
28
214
9
40
2.27
1.40
2.7
2.4
—
—
—
0
0
11
211
0.51
1.40
1.5
1.5
—
—
—
0
0
7
29
2.43
1.39
1.0
1.1
—
—
—
0
0
7
29
2.43
1.39
2.6
3.6
—
—
—
0
0
79
622
1.30
1.38
1.3
1.3
—
—
—
0
0
19
112
1.72
1.36
1.3
1.2
92.1
28.7
u/l
0.67
14
97
14
75
1.88
1.35
1.8
1.6
46.9
65.4
%
—
9
51
6
24
2.51
1.30
1.3
1.2
4.9
35.2
%
—
6
19
578
5973
0.81
1.28
48.6
23.0
4.2
4.4
e12/l
20.22
570
5785
578
5972
0.81
1.27
48.4
22.9
30.3
30.4
pg
0.21
572
5865
578
5971
0.81
1.26
48.5
22.9
92.3
91.5
fl
3.34
572
5865
578
5970
0.81
1.24
48.9
23.0
256.9
245.5
e9/l
3.31
570
5800
579
5974
0.82
1.19
48.6
23.0
7.3
6.7
e9/l
7.98
571
5786
6
26
2.32
1.19
2.7
3.9
—
—
—
0
0
6
26
2.32
1.19
2.3
2.8
1190.5
1356.0
u/ml
—
6
26
10
186
0.53
1.18
1.8
1.6
—
—
—
0
0
22
141
1.58
1.18
1.7
2.6
—
—
—
0
0
8
39
2.06
1.15
1.1
1.1
—
—
—
0
0
8
153
0.52
1.15
1.1
1.1
—
—
—
0
0
16
96
1.68
1.11
1.9
1.6
—
—
—
0
0
8
41
1.96
1.09
1.3
1.2
—
—
—
0
0
8
41
1.96
1.09
1.3
1.2
—
—
—
0
0
25
169
1.50
1.08
1.6
1.4
0.2
0.2
g/l
0.38
25
158
7
33
2.13
1.05
1.3
2.4
—
—
—
0
0
9
46
1.97
1.04
1.6
1.1
—
—
—
0
0
48
615
0.76
1.02
5.5
4.1
—
—
—
0
0
34
249
1.38
0.99
2.0
2.8
—
—
—
0
0
7
36
1.95
0.97
3.0
3.4
—
—
—
0
0
25
176
1.44
0.92
1.2
1.2
—
—
—
0
0
10
58
1.73
0.80
2.2
2.2
—
—
—
0
0
139
1553
0.87
0.77
1.7
1.6
1.5
1.3
mmol/l
0.91
104
1280
164
1811
0.88
0.77
3.3
3.1
887.4
227.2
mg/l
0.56
98
1107
20
141
1.43
0.75
3.0
2.6
54.2
85.6
ug/min
0.48
11
85
108
947
1.17
0.74
3.6
3.2
1.6
2.3
e6/l
0.88
66
514
9
55
1.64
0.73
1.0
1.1
—
—
—
0
0
35
273
1.30
0.72
1.2
1.2
—
—
—
0
0
7
39
1.80
0.72
1.6
2.1
—
—
—
0
0
9
56
1.61
0.72
1.0
1.1
—
—
—
0
0
152
1370
1.14
0.72
2.9
2.4
—
—
—
0
0
7
41
1.71
0.70
1.3
1.6
—
—
—
0
0
7
41
1.71
0.70
1.3
1.1
—
—
—
0
0
11
169
0.65
0.69
1.6
1.8
—
—
—
0
0
7
42
1.67
0.68
1.3
1.1
—
—
—
0
0
167
1525
1.13
0.65
1.7
1.6
19.9
21.3
nmol/l
0.63
149
1273
169
1841
0.89
0.63
3.3
3.1
6.2
7.0
mmol/l
1.97
126
1512
176
1906
0.90
0.60
4.5
3.9
8.0
7.6
mg/mmol
0.05
94
1149
24
310
0.77
0.60
3.7
2.9
0.0
0.3
e6/l
2.91
24
302
493
4779
1.11
0.59
31.4
17.0
37.4
38.9
%
2.26
279
3126
0
22
0.00
0.59
0.0
2.5
—
—
—
0
0
6
36
1.67
0.56
1.0
1.0
377.0
293.0
mg/l
—
6
30
11
73
1.52
0.56
1.0
1.1
—
—
—
0
0
6
37
1.63
0.55
1.5
1.2
—
—
—
0
0
16
116
1.39
0.55
1.7
1.6
—
—
—
0
0
62
536
1.17
0.54
1.6
1.6
—
—
—
0
0
6
98
0.61
0.52
1.5
2.0
31.7
44.1
nmol/l
—
6
92
6
40
1.50
0.51
4.7
1.4
—
—
—
0
0
6
41
1.47
0.50
1.2
1.1
—
—
—
0
0
569
5798
0.90
0.49
23.1
10.8
24.8
24.6
u/l
0.19
562
5570
7
48
1.46
0.47
2.3
2.1
—
—
—
0
0
55
483
1.15
0.42
4.5
3.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
8
60
1.34
0.40
1.8
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
11
81
1.36
0.36
1.1
1.8
—
—
—
0
0
14
176
0.79
0.32
9.2
10.5
—
—
—
0
0
12
92
1.31
0.32
1.2
1.2
—
—
—
0
0
34
299
1.14
0.28
2.4
2.2
8.8
12.7
nmol/l
2.38
29
252
36
318
1.14
0.28
1.3
1.2
142.4
155.4
iu/ml
—
9
115
5
39
1.28
0.23
2.6
3.7
—
31.4
u/ml
—
0
12
43
391
1.11
0.22
1.2
1.2
—
—
—
0
0
115
1210
0.94
0.22
6.0
4.5
1.0
1.0
kg/l
0.24
16
176
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
8.3
—
—
—
0
0
35
387
0.90
0.21
3.7
3.0
—
—
—
0
0
571
5764
0.95
0.19
35.5
18.4
4.0
4.0
mmol/l
0.45
559
5591
570
5751
0.95
0.18
35.1
18.3
139.0
139.7
mmol/l
7.02
558
5583
7
61
1.15
0.17
1.4
1.2
—
—
—
0
0
8
68
1.18
0.16
1.3
1.3
—
—
—
0
0
22
246
0.89
0.16
3.1
1.9
—
—
—
0
0
19
214
0.88
0.16
1.1
1.1
—
32.2
titre
—
0
5
19
168
1.13
0.16
1.1
1.1
—
—
—
0
0
19
213
0.89
0.15
2.6
2.9
0.1
0.2
g/l
1.21
11
76
31
285
1.09
0.14
1.3
1.3
—
—
—
0
0
10
84
1.19
0.14
1.5
1.1
—
—
—
0
0
10
85
1.18
0.12
2.5
2.7
—
—
—
0
0
12
135
0.89
0.10
3.3
2.3
—
—
—
0
0
10
87
1.15
0.09
1.2
1.1
—
—
—
0
0
5
47
1.06
0.09
1.0
1.1
—
—
—
0
0
6
57
1.05
0.08
3.8
1.2
—
—
—
0
0
5
61
0.82
0.08
1.0
1.1
—
163.1
—
0
12
5
65
0.77
0.08
1.6
1.2
—
—
—
0
0
10
111
0.90
0.06
1.0
1.2
—
—
—
0
0
38
366
1.04
0.05
4.8
3.2
5.0
4.0
e9/l
1.00
29
259
564
5620
1.02
0.05
32.4
14.8
—
—
—
0
0
130
1318
0.98
0.04
5.0
4.0
—
—
—
0
0
10
91
1.10
0.04
2.6
1.4
—
—
—
0
0
253
2547
0.99
0.03
2.0
2.1
93.0
94.0
pmol/l
0.13
129
1265
31
301
1.03
0.02
4.7
4.0
—
—
—
0
0
22
228
0.96
0.02
1.4
1.6
—
—
—
0
0
508
5073
1.01
0.00
6.0
4.9
2.1
2.2
mu/l
0.26
456
4541
17
164
1.04
0.00
5.4
5.2
—
—
—
0
0
34
334
1.02
0.00
1.3
1.3
—
—
—
0
0
15
147
1.02
0.00
1.1
1.1
—
—
—
0
0
112
1123
1.00
0.00
1.3
1.2
0.5
1.6
u/ml
2.35
22
273
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
7
75
0.93
0.00
3.6
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
2.6
—
17.1
—
0
9
6
66
0.91
0.00
1.3
1.3
—
—
—
0
0
7
75
0.93
0.00
3.6
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
36.3
—
0
9
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
7
74
0.95
0.00
3.6
1.2
—
—
—
0
0
7
70
1.00
0.00
3.6
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
0.00
3.6
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.1
—
0
5
5
50
1.00
0.00
1.0
1.6
13.4
10.1
%
—
5
50
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint J10_RESPCONDEXT and mortality.

Females

Parameter HR [95% CI] p-value
J10_RESPCONDEXT 2.553 [2.22, 2.94] < 0.001
Birth year 0.995 [0.99, 1.0] 0.283

During the follow-up period (1.1.1998 — 31.12.2019), 1081 out of 2197 females with J10_RESPCONDEXT died.

Males

Parameter HR [95% CI] p-value
J10_RESPCONDEXT 4.277 [3.44, 5.32] < 0.001
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 953 out of 1460 males with J10_RESPCONDEXT died.

Mortality risk

Mortality risk for people of age

years, who have J10_RESPCONDEXT.

N-year risk Females Males
1 0.267% 0.724%
5 1.56% 4.682%
10 3.869% 11.389%
15 6.993% 21.879%
20 12.541% 33.517%

Relationships between endpoints

Index endpoint: J10_RESPCONDEXT – Respiratory conditions due to other external agents

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data