esophageal varices: Abnormally dilated veins of the esophagus.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1457 |
4. Check minimum number of eventsNone |
1457 |
5. Include endpointsNone |
1457 |
6. Filter based on genotype QC (FinnGen only) |
1457 |
Control definitions (FinnGen only)
- Control exclude
- I9_DISVEINLYMPH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I80-I89
- Name in latin
- Varices oesophagi
Similar endpoints
↥List of similar endpoints to
Oesophageal varices
based on the number of shared cases.
Similar with more cases:
- Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
- Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)
- Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 15571 | 4582 | 10653 |
| Only index persons | 9567 | 3029 | 6538 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.25 | 0.13 | 0.30 |
| Only index persons | 0.21 | 0.11 | 0.25 |
| Median age at first event (years) | |||
| Whole population | 59.23 | 62.25 | 57.96 |
| Only index persons | 60.61 | 62.62 | 59.68 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1457 | 509 | 948 |
| Unadjusted period prevalence (%) | 0.33 | 0.17 | 0.42 |
| Median age at first event (years) | 62.47 | 62.87 | 62.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1292
- Matched controls
- 12920
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
171.8
323.0
492
46
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
+∞
323.0
403
*
C03DA01
ATC
spironolactone; oral
21.6
323.0
727
726
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
23.5
323.0
1082
2320
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
129.6
323.0
544
72
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
752.5
323.0
337
6
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
4503599627370496.0
323.0
1079
*
R18
ICD-10 Finland
Ascites
59.5
288.0
337
76
C07AA05
ATC
propranolol; systemic
9.8
262.8
646
1191
K92.0
ICD-10 Finland
Haematemesis
33.7
240.9
320
125
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
11.4
215.2
447
570
C03CA01
ATC
furosemide; systemic
6.5
205.8
779
2458
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.1
191.2
507
955
K92.1
ICD-10 Finland
Melaena
13.4
172.3
320
309
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
34.1
172.2
227
80
A06AD11
ATC
lactulose; oral
6.9
168.0
505
1104
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
23.2
142.8
210
107
Z94.4
ICD-10 Finland
Liver transplant status
128.9
120.4
128
11
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
55.4
117.1
139
28
D64.9
ICD-10 Finland
Anaemia, unspecified
6.3
113.2
343
704
JJC00
NOMESCO Finland
Allogenic transplantation of liver
247.1
111.6
113
5
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
21.0
109.7
166
90
K70.4
ICD-10 Finland
Alcoholic hepatic failure
78.9
108.5
122
17
C07AG02
ATC
carvedilol; oral
7.5
98.8
253
405
I81
ICD-10 Finland
Portal vein thrombosis
+∞
97.1
92
*
A07AA11
ATC
rifaximin; oral
261.7
96.0
97
*
127
Kela drug reimbursment
Transplant complication
20.6
87.0
132
71
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
34.9
85.9
112
35
K70.1
ICD-10 Finland
Alcoholic hepatitis
40.5
85.7
108
29
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
6.7
85.4
236
415
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
6.1
80.0
237
455
UJF32
NOMESCO Finland
Coloscopy
3.4
79.5
518
2129
A05AA02
ATC
ursodeoxycholic acid; oral
23.0
78.1
114
54
K70.9
ICD-10 Finland
Alcoholic liver disease, unspecified
72.4
77.4
88
13
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
10.7
77.3
156
164
A02BC02
ATC
pantoprazole; systemic
3.2
75.1
981
6417
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.3
74.7
500
2076
L04AA06
ATC
mycophenolic acid; systemic
18.1
73.2
116
70
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
156.7
70.7
74
5
K72.1
ICD-10 Finland
Chronic hepatic failure
156.7
70.7
74
5
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
69.9
546
2496
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
354.9
68.2
68
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
5.4
67.7
221
471
A10AE04
ATC
insulin glargine; parenteral
4.7
66.9
257
654
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
52.4
66.1
79
16
N02AX02
ATC
tramadol; systemic, rectal
2.7
64.6
707
3941
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
11.2
61.5
120
117
WW500
NOMESCO Finland
Blood transfusion
7.7
61.3
150
217
D97
ICPC
Liver disease NOS
41.2
59.2
74
19
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
13.3
58.7
105
85
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
9.5
58.3
124
142
K72.9
ICD-10 Finland
Hepatic failure, unspecified
51.1
56.7
68
14
UJD02
NOMESCO Finland
Gastroscopy
6.2
56.1
160
286
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
55.4
394
1636
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
54.4
340
1289
L04AD01
ATC
ciclosporin; systemic
11.6
52.9
101
94
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
+∞
52.4
50
*
JJ5AT
NOMESCO Finland
NA
143.4
52.2
55
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.8
51.9
248
759
K83.0
ICD-10 Finland
Cholangitis
15.0
51.4
87
62
K76.7
ICD-10 Finland
Hepatorenal syndrome
114.7
51.2
55
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.4
49.6
702
4266
K76.9
ICD-10 Finland
Liver disease, unspecified
14.9
49.0
83
59
K70.0
ICD-10 Finland
Alcoholic fatty liver
23.8
48.8
70
31
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.5
48.7
187
466
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
9.4
48.3
103
118
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.6
48.1
456
2227
K29.6
ICD-10 Finland
Other gastritis
15.9
47.3
78
52
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
47.2
45
*
I86.4
ICD-10 Finland
Gastric varices
+∞
46.1
44
*
A10BA02
ATC
metformin; oral
2.5
45.8
496
2587
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
23.1
45.7
66
30
K76.6
ICD-10 Finland
Portal hypertension
463.0
45.5
45
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.3
45.2
126
217
4560A
ICD-9 Finland
Varicose veins of other sites, Oesophageal varices with bleeding
+∞
45.0
43
*
K74.3
ICD-10 Finland
Primary biliary cirrhosis
41.7
45.0
56
14
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
29.9
44.7
60
21
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.8
44.5
106
146
WX002
NOMESCO Finland
Sedation and analgesia
2.7
43.1
351
1548
T90
ICPC
Diabetes non-insulin dependent
2.5
42.9
427
2113
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
16.0
42.7
70
46
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
12.0
40.8
76
67
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
40.7
297
1219
P15
ICPC
Chronic alcohol abuse
7.2
39.8
100
149
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.9
39.5
178
511
B18.2
ICD-10 Finland
Chronic viral hepatitis C
20.5
39.5
59
30
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.1
38.9
79
83
PHD99
NOMESCO Finland
Resection of other vein
+∞
38.7
37
*
TK800
NOMESCO Finland
Hemodialysis
7.8
38.7
92
126
JN3AD
NOMESCO Finland
Abdominal CT examination
3.8
38.5
178
522
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
36.3
38.3
49
14
F10.20
ICD-10 Finland
Alcohol dependence currently independent
8.6
37.9
84
103
WX892
NOMESCO Finland
Monitored bed care
3.8
37.7
176
520
I85
ICD-10 Finland
Oesophageal varices
+∞
37.7
36
*
J01MA02
ATC
ciprofloxacin; systemic
2.2
37.7
589
3581
ZX120
NOMESCO Finland
Intravenous
3.4
36.5
193
630
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
15.4
35.6
59
40
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
35.2
215
778
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.2
34.7
205
725
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
9.4
34.6
73
82
F10.25
ICD-10 Finland
Alcohol dependence continuous use
8.7
33.5
74
90
K29.7
ICD-10 Finland
Gastritis, unspecified
5.5
33.5
104
204
A10BH01
ATC
sitagliptin; oral
3.1
33.4
205
740
K70.2
ICD-10 Finland
Alcoholic fibrosis and sclerosis of liver
119.7
32.8
35
*
8000/3-C22.0
ICD-O-3
Neoplasm, malignant of liver
119.7
32.8
35
*
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.7
32.3
153
455
PHD76
NOMESCO Finland
Resection of long saphenous vein
+∞
31.4
30
*
JN4CD
NOMESCO Finland
Very extensive body CT
4.5
31.2
116
277
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
10.1
30.8
62
64
TKC20
NOMESCO Finland
Catheterisation of bladder
3.5
30.7
152
468
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
16.4
30.4
49
31
R4110
NOMESCO Finland
Physiotherapy
2.2
30.2
407
2259
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.9
29.5
196
744
XF400
NOMESCO Finland
ECG with 12 standard connections
2.4
29.3
282
1330
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
28.5
453
2683
A10AE05
ATC
insulin detemir; parenteral
4.0
28.3
120
324
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
+∞
28.2
27
*
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
5.7
28.2
83
153
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
18.5
28.0
43
24
L04AX01
ATC
azathioprine; systemic
5.1
27.9
91
189
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
79.4
27.9
31
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.1
27.7
114
299
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.8
27.5
194
764
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
27.2
168
606
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.7
27.2
80
147
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
6.2
27.2
75
127
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
27.1
426
2500
A10BB12
ATC
glimepiride; oral
3.2
27.0
153
521
UJF30
NOMESCO Finland
Ileoscopy through colon
3.0
27.0
166
597
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
26.8
264
1254
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.5
26.7
71
115
Z51.5
ICD-10 Finland
Palliative care
3.6
26.4
124
365
R50.9
ICD-10 Finland
Fever, unspecified
2.5
26.1
226
1001
K74.0
ICD-10 Finland
Hepatic fibrosis
61.3
26.0
30
5
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
31.7
26.0
34
11
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
15.4
25.6
42
28
C22.9
ICD-10 Finland
Malignant neoplasm: Liver, unspecified
36.4
25.3
32
9
K73.0
ICD-10 Finland
Chronic persistent hepatitis, not elsewhere classified
254.6
24.7
25
*
F10.24
ICD-10 Finland
Alcohol depence active use
7.9
24.7
57
75
JN4BD
NOMESCO Finland
Extensive body CT
2.6
24.7
199
845
H02AB04
ATC
methylprednisolone; systemic
2.4
24.4
228
1049
N07BB01
ATC
disulfiram; oral
4.0
24.3
102
273
JDA32
NOMESCO Finland
Endoscopic injection in stomach or pylorus
23.2
24.0
34
15
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.3
23.6
91
225
N05BA04
ATC
oxazepam; oral
2.1
23.4
329
1823
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.2
23.3
262
1317
AA1AD
NOMESCO Finland
CT of head and brain
2.0
23.0
351
2010
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
+∞
23.0
22
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.4
23.0
85
202
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
40.8
22.7
28
7
JDA22
NOMESCO Finland
Endoscopic ligature of varices of stomach
233.8
22.7
23
*
XW000
NOMESCO Finland
Bone marrow biopsy
4.1
22.6
92
239
EBA15
NOMESCO Finland
Extraction of large number of teeth
3.9
22.3
96
263
G93.4
ICD-10 Finland
Encephalopathy, unspecified
35.7
22.1
28
8
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
3.5
21.9
108
331
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
20.5
21.7
32
16
5712A
ICD-9 Finland
Chronic liver disease and cirrhosis, Alcoholic cirrhosis of liver
116.9
21.6
23
*
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
6.5
21.4
56
89
SPAT1262
SPAT
Handing over of treatment supplies
2.1
21.2
295
1620
198
Kela drug reimbursment
Sorafenib
34.4
21.2
27
8
J01MA12
ATC
levofloxacin; systemic
2.1
21.1
281
1515
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.4
21.0
108
341
K65.0
ICD-10 Finland
Acute peritonitis
9.2
20.7
43
48
N05CF01
ATC
zopiclone; oral
1.8
20.5
435
2790
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.3
20.5
106
337
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
8.5
20.2
44
53
N06AX11
ATC
mirtazapine; oral
1.9
20.1
397
2477
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.4
20.0
99
304
A46
ICD-10 Finland
Erysipelas
2.3
19.9
202
962
1324
FHL
Esophagoscopy and sclerotherapy
+∞
19.8
19
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
19.8
161
683
A28
ICPC
Limited function/disability NOS
2.3
19.7
212
1035
K74.5
ICD-10 Finland
Biliary cirrhosis, unspecified
74.6
19.7
22
*
WX882
NOMESCO Finland
High dependency care
4.4
19.6
73
175
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.5
19.4
93
279
K83.1
ICD-10 Finland
Obstruction of bile duct
7.6
19.3
45
61
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
12.4
19.1
34
28
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
19.1
212
1051
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.3
18.6
71
174
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.0
18.5
60
125
JN4AD
NOMESCO Finland
Body CT examination
2.7
18.3
136
546
SPAT1255
SPAT
Intravenous administration of medicine
3.0
18.2
111
396
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.6
18.2
85
250
N02AA05
ATC
oxycodone; systemic
2.1
18.0
215
1097
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
15.6
18.0
29
19
TJA10
NOMESCO Finland
Laparocentesis
33.4
18.0
23
7
B01AB05
ATC
enoxaparin; parenteral
1.8
18.0
377
2387
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
16.8
17.9
28
17
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.8
17.8
120
457
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
10.5
17.7
34
33
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
37.2
17.6
22
6
A02BC01
ATC
omeprazole; systemic
1.8
17.6
368
2322
D73.1
ICD-10 Finland
Hypersplenism
96.3
17.6
19
*
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
182.2
17.5
18
*
R41.0
ICD-10 Finland
Disorientation, unspecified
4.3
17.5
65
156
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
3.5
17.5
85
258
M04AA01
ATC
allopurinol; systemic
2.1
17.1
211
1091
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
5.3
16.9
52
102
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
16.7
204
1050
D25
ICPC
Abdominal distension
7.2
16.7
40
57
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
6.6
16.5
42
65
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
10.2
16.5
32
32
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
10.2
16.5
32
32
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
9.6
16.4
33
35
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
23.4
16.4
23
10
A41.8
ICD-10 Finland
Other specified sepsis
6.2
16.4
44
73
A10BH05
ATC
linagliptin; oral
3.2
16.4
88
288
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.8
16.3
69
187
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
8.5
16.3
35
42
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
16.2
144
637
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
16.1
360
2309
JCA42
NOMESCO Finland
Other endoscopic procedure for hemostasis
30.4
16.1
21
7
C10AC01
ATC
colestyramine; oral
4.5
16.1
57
131
K86.1
ICD-10 Finland
Other chronic pancreatitis
9.1
16.0
33
37
WX872
NOMESCO Finland
Intensive care
2.9
15.8
99
358
L01XE05
ATC
[U] sorafenib; oral
33.8
15.7
20
6
UJF92
NOMESCO Finland
Capsular endoscopy
5.2
15.7
49
98
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
+∞
15.6
15
*
JCA35
NOMESCO Finland
Endoscopic contact coagulation in oesophagus
+∞
15.6
15
*
3AC01
NOMESCO Finland
NA
8.6
15.5
33
39
UJC12
NOMESCO Finland
Flexible oesophagoscopy
10.2
15.5
30
30
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.7
15.4
68
191
PC2DT
NOMESCO Finland
Embolisation of lesion of liver
38.5
15.4
19
5
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.9
15.2
96
348
K29.2
ICD-10 Finland
Alcoholic gastritis
18.0
15.2
23
13
R60.0
ICD-10 Finland
Localized oedema
2.3
15.1
145
669
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.3
15.1
56
135
K73.9
ICD-10 Finland
Chronic hepatitis, unspecified
14.1
15.0
25
18
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
7.7
14.9
34
45
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
32.1
14.8
19
6
B82
ICPC
Anaemia other/unspecified
4.5
14.8
52
119
E87.6
ICD-10 Finland
Hypokalaemia
3.9
14.7
61
163
R53
ICD-10 Finland
Malaise and fatigue
1.9
14.7
246
1429
K73.80
ICD-10 Finland
Non-alcoholic fatty liver (NASH, Non Alcoholic Steatohepatitis)
21.3
14.7
21
10
4561A
ICD-9 Finland
Varicose veins of other sites, Oesophageal varices without mention of bleeding
+∞
14.6
14
*
P16
ICPC
Acute alcohol abuse
6.1
14.6
39
65
160
Kela drug reimbursment
exenatide
4.7
14.6
49
107
A98
ICPC
Health maint/preventive medicine
0.6
14.6
993
11050
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.6
14.5
112
462
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
4.3
14.5
53
126
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.3
14.3
72
225
K65.8
ICD-10 Finland
Other peritonitis
27.5
14.3
19
7
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
8.7
14.3
30
35
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
4.8
14.2
47
101
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.0
14.2
82
283
N05CD07
ATC
temazepam; oral
2.1
14.2
182
953
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
14.1
378
2546
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
7.3
14.0
33
46
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
6.5
14.0
36
57
UJK02
NOMESCO Finland
ERCP
3.9
14.0
57
150
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
13.9
58
156
SPAT1088
SPAT
Blood transfusion
10.6
13.7
26
25
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
7.7
13.7
31
41
R04.0
ICD-10 Finland
Epistaxis
2.5
13.6
111
470
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.7
13.5
96
377
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
5.3
13.5
41
80
S42.2
ICD-10 Finland
Fracture of upper end of humerus
3.2
13.5
70
224
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.0
13.5
78
269
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
13.3
397
2745
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
13.2
245
1470
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.2
13.1
50
124
A41.9
ICD-10 Finland
Sepsis, unspecified
3.2
13.0
68
219
RS220
NOMESCO Finland
NA
6.8
13.0
32
48
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
4.7
13.0
43
93
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
22.8
12.9
18
8
K42.0
ICD-10 Finland
Umbilical hernia with obstruction, without gangrene
6.7
12.8
32
49
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
7.3
12.8
30
42
E87.5
ICD-10 Finland
Hyperkalaemia
5.5
12.7
37
69
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
7.6
12.7
29
39
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
7.1
12.6
30
43
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
5.1
12.5
39
79
5716A
ICD-9 Finland
Chronic liver disease and cirrhosis, Biliary cirrhosis[CIRRHOSIS BILIARIS PRIMARIA]
131.1
12.4
13
*
L28
ICPC
Limited function/disability (L)
1.9
12.4
191
1071
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.6
12.3
89
354
SPAT1265
SPAT
Breathalyser
7.2
12.3
29
41
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
12.3
243
1486
F10.09
ICD-10 Finland
Alcohol intoxication UNS
4.5
12.2
43
99
K85
ICD-10 Finland
Acute pancreatitis
4.7
12.2
41
90
D64.8
ICD-10 Finland
Other specified anaemias
5.0
12.2
38
77
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.1
12.1
141
708
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
4.7
12.0
40
87
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
11.2
12.0
22
20
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
4.6
12.0
41
92
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
11.9
475
3514
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
47.1
11.9
14
*
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
11.8
11.8
21
18
Z72.1
ICD-10 Finland
Alcohol use
5.7
11.8
33
59
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.5
11.8
94
393
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
10.6
11.8
22
21
N05AH04
ATC
quetiapine; oral
1.9
11.7
175
971
A02BC03
ATC
lansoprazole; oral
1.6
11.7
347
2382
A10BB01
ATC
glibenclamide; oral
2.9
11.6
69
244
I86.8
ICD-10 Finland
Varicose veins of other specified sites
65.5
11.6
13
*
A10BG03
ATC
pioglitazone; oral
3.6
11.4
50
141
K74.2
ICD-10 Finland
Hepatic fibrosis with hepatic sclerosis
120.9
11.4
12
*
B80
ICPC
Iron deficiency anaemia
4.7
11.4
38
83
SPAT1254
SPAT
Administration of medicine
1.9
11.4
178
1004
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.6
11.4
50
142
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
3.8
11.2
47
128
K29.1
ICD-10 Finland
Other acute gastritis
5.5
11.2
32
59
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.6
11.2
81
323
K75.4
ICD-10 Finland
Autoimmune hepatitis
25.2
11.1
15
6
K76.89
ICD-10 Finland
Other specified diseases of liver
20.2
11.1
16
8
D50.8
ICD-10 Finland
Other iron deficiency anaemias
6.5
11.1
28
44
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.2
11.1
41
100
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
7.1
11.1
26
37
WVA20
NOMESCO Finland
Medicine administration
4.1
11.0
42
105
JAH00
NOMESCO Finland
Laparotomy
3.4
11.0
52
157
M10.9
ICD-10 Finland
Gout, unspecified
2.3
11.0
105
482
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.2
10.9
33
65
K22.1
ICD-10 Finland
Ulcer of oesophagus
3.8
10.9
45
121
A10BJ02
ATC
liraglutide; parenteral
3.9
10.8
43
112
JN3KE
NOMESCO Finland
Abdominal ultrasound with added contrast
9.7
10.8
21
22
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
10.7
249
1593
I50.9
ICD-10 Finland
Heart failure, unspecified
1.9
10.7
176
1007
K51.5
ICD-10 Finland
Left sided colitis
4.0
10.6
41
104
RS122
NOMESCO Finland
NA
60.5
10.6
12
*
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
6.1
10.6
28
47
J01FF01
ATC
clindamycin; systemic
1.6
10.6
320
2199
A12BA01
ATC
potassium chloride; oral
2.8
10.5
67
248
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
10.1
10.5
20
20
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
14.3
10.5
17
12
UJD10
SPAT
NA
5.7
10.4
29
52
I98.2
ICD-10 Finland
Oesophageal varices without bleeding in diseases classified elsewhere
+∞
10.4
10
*
A02BA03
ATC
famotidine; systemic
2.8
10.4
66
244
J94.8
ICD-10 Finland
Other specified pleural conditions
4.6
10.4
35
78
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.9
10.4
25
37
3A422
NOMESCO Finland
NA
32.8
10.3
13
*
E66.00
ICD-10 Finland
Metabolic syndrome
2.5
10.3
79
325
K70
ICD-10 Finland
Alcoholic liver disease
23.5
10.2
14
6
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
6.3
10.2
26
42
K86.3
ICD-10 Finland
Pseudocyst of pancreas
8.5
10.1
21
25
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
5.2
10.0
30
59
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
6.1
10.0
26
43
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.9
10.0
60
215
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
10.0
134
715
A09AA02
ATC
multienzymes (lipase, protease etc.)
4.2
9.9
36
87
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
16.8
9.9
15
9
H26.3
ICD-10 Finland
Drug-induced cataract
12.3
9.9
17
14
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
9.8
88
393
PC2ET
NOMESCO Finland
Extensive embolisation of lesion of liver
26.2
9.8
13
5
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
26.2
9.8
13
5
XX4BW
NOMESCO Finland
NA
20.2
9.8
14
7
L04AA01
ATC
[U] ciclosporin; systemic
4.5
9.8
33
74
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.9
9.8
58
206
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.0
9.8
134
720
A10BD07
ATC
metformin and sitagliptin; systemic
2.5
9.7
78
328
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.7
9.7
41
114
E88.0
ICD-10 Finland
Disorders of plasma-protein metabolism, not elsewhere classified
55.4
9.7
11
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
9.6
287
1960
N06AX16
ATC
venlafaxine; oral
1.9
9.6
142
783
A40.8
ICD-10 Finland
Other streptococcal sepsis
6.4
9.6
24
38
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
10.1
9.5
18
18
R60.9
ICD-10 Finland
Oedema, unspecified
2.7
9.5
64
245
UJK12
NOMESCO Finland
Peroral cholangioscopy
15.1
9.5
15
10
N19
ICD-10 Finland
Unspecified kidney failure
2.9
9.4
56
200
I82.0
ICD-10 Finland
Budd-Chiari syndrome
+∞
9.4
9
*
N06AB04
ATC
citalopram; systemic
1.6
9.4
243
1598
JAF10
NOMESCO Finland
Repair of umbilical hernia
3.4
9.4
44
133
B18.1
ICD-10 Finland
Chronic viral hepatitis B without delta-agent
21.8
9.4
13
6
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.3
9.3
84
376
0092A
ICD-9 Finland
Ill-defined intestinal infections, Infectious diarrhoea
8.7
9.3
19
22
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
9.6
9.3
18
19
G62.1
ICD-10 Finland
Alcoholic polyneuropathy
9.6
9.3
18
19
A10BX04
ATC
[U] exenatide; parenteral
5.1
9.3
28
56
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.9
9.3
36
93
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.9
9.2
54
190
R40.2
ICD-10 Finland
Coma, unspecified
7.3
9.2
21
29
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
5.8
9.2
25
44
C10AA07
ATC
rosuvastatin; oral
0.6
9.2
144
2278
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
9.2
172
1026
WX402
NOMESCO Finland
General anaesthesia
1.7
9.2
201
1262
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
9.2
93
439
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
4.3
9.1
32
75
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
15.7
9.0
14
9
ZX108
NOMESCO Finland
Inhalation
7.1
9.0
21
30
N40
ICD-10 Finland
Hyperplasia of prostate
0.6
9.0
150
2340
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.5
9.0
68
278
XCK10
NOMESCO Finland
Photography of fundus of eye
1.9
9.0
132
728
SAA03
NOMESCO Finland
Extended examination of mouth
1.5
9.0
402
3010
RS120
NOMESCO Finland
NA
18.7
8.9
13
7
JJA20
NOMESCO Finland
Open biopsy of liver
18.7
8.9
13
7
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.2
8.9
45
144
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
12.6
8.9
15
12
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
12.6
8.9
15
12
N05BA01
ATC
diazepam; systemic, rectal
1.8
8.8
159
939
ZXA00
NOMESCO Finland
Right side
1.5
8.8
317
2258
D45
ICD-10 Finland
Polycythaemia vera
6.4
8.8
22
35
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.7
8.8
37
103
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
3.7
8.8
36
98
A10AE06
ATC
insulin degludec; parenteral
3.2
8.8
45
146
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.5
8.7
69
290
E000001
ATC
NA
1.7
8.7
213
1378
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
4.1
8.7
32
79
R4190
NOMESCO Finland
Nutritional therapy
2.9
8.7
51
181
R11
ICD-10 Finland
Nausea and vomiting
2.2
8.7
85
397
V03AE01
ATC
polystyrene sulfonate; oral
5.1
8.7
26
52
A10BX07
ATC
[U] liraglutide; parenteral
4.8
8.6
27
57
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.4
8.6
40
121
D69.5
ICD-10 Finland
Secondary thrombocytopenia
16.4
8.6
13
8
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.0
8.5
107
556
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
8.5
151
884
K26.4
ICD-10 Finland
Duodenal ulcer, chronic or unspecified with haemorrhage
9.0
8.5
17
19
205
Kela drug reimbursment
Chronic hypertension
1.5
8.5
361
2661
OAB43
SPAT
NA
0.4
8.5
27
724
JX1XE
NOMESCO Finland
Other ultrasound examinaton of alimentary organs
27.7
8.5
11
*
S97
ICPC
Chronic ulcer skin
2.4
8.5
71
308
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
5.7
8.4
23
41
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.5
8.4
93
1614
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
4.7
8.4
27
58
E0000UV
ATC
NA
1.5
8.4
409
3104
P01AB01
ATC
metronidazole; oral, rectal
1.5
8.4
398
3006
Z94.0
ICD-10 Finland
Kidney transplant status
4.9
8.4
26
54
WX730
NOMESCO Finland
Conventional respirator
4.0
8.4
32
82
Q44.29
ICD-10 Finland
Atresia of bile ducts
+∞
8.3
8
*
4520A
ICD-9 Finland
Portal vein thrombosis[THROMBOSIS VENAE PORTAE]
+∞
8.3
8
*
PH3YT
NOMESCO Finland
Insertion of catheter from portal vein to liver vein (TIPS)
+∞
8.3
8
*
TJC00
NOMESCO Finland
Insertion of ballon tube for tamponade of oesophageal varices
+∞
8.3
8
*
R06.0
ICD-10 Finland
Dyspnoea
1.5
8.3
281
1970
WX213
NOMESCO Finland
Lower leg blockade
8.6
8.3
17
20
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
5.6
8.3
23
42
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
10.8
8.3
15
14
J01DA01
ATC
[U] cefalexin; systemic
1.4
8.3
700
5894
JJ6LT
NOMESCO Finland
Coagulation of focal hepatic lesion under ultrasound guidance
14.6
8.2
13
9
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
0.0
8.1
*
200
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
8.1
119
653
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
8.1
139
807
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
8.1
346
2552
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
11.8
8.1
14
12
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
10.1
8.0
15
15
SPAT1247
SPAT
Outpatient detoxication and monitoring
10.1
8.0
15
15
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
10.1
8.0
15
15
JKD20
NOMESCO Finland
Anastomosis of bile duct to jejunum
22.1
8.0
11
5
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.9
8.0
46
160
N05BA02
ATC
chlordiazepoxide; systemic
3.1
8.0
42
139
K07
ICPC
Swollen ankles/oedema
2.7
8.0
52
197
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
7.9
210
1385
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
13.1
7.9
13
10
F10.41
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol with seizures
10.9
7.8
14
13
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.2
7.8
38
120
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.6
7.7
53
206
A07AA02
ATC
nystatin; oral
2.2
7.7
72
331
F10.4
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Withdrawal state with delirium
15.1
7.7
12
8
JJA44
NOMESCO Finland
Laparoscopic destruction of lesion of liver
45.2
7.7
9
*
L04AA10
ATC
sirolimus; oral
45.2
7.7
9
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.6
7.7
25
55
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
5.6
7.7
21
38
H02AB09
ATC
hydrocortisone; systemic
3.3
7.7
36
110
A07EC02
ATC
mesalazine; oral, rectal
2.3
7.7
66
292
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
3.5
7.6
33
95
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
8.1
7.6
16
20
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
11.9
7.6
13
11
I78.8
ICD-10 Finland
Other diseases of capillaries
11.9
7.6
13
11
K55.8
ICD-10 Finland
Other vascular disorders of intestine
8.9
7.5
15
17
K26.7
ICD-10 Finland
Duodenal ulcer, chronic without haemorrhage or perforation
8.9
7.5
15
17
N06AB10
ATC
escitalopram; oral
1.6
7.5
185
1197
R73.9
ICD-10 Finland
Hyperglycaemia, unspecified
3.1
7.5
38
123
K08.3
ICD-10 Finland
Retained dental root
2.0
7.4
92
475
TJA00
NOMESCO Finland
Puncture of peritoneum
80.5
7.4
8
*
2BB01
NOMESCO Finland
NA
80.5
7.4
8
*
J01DB01
ATC
cefalexin; oral
1.4
7.4
943
8453
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
7.7
7.4
16
21
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
6.0
7.4
19
32
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.1
7.3
37
120
E83.1
ICD-10 Finland
Disorders of iron metabolism
10.9
7.3
13
12
W10
ICD-10 Finland
Fall on and from stairs and steps
2.3
7.3
63
278
K74.4
ICD-10 Finland
Secondary biliary cirrhosis
+∞
7.3
7
*
JKD50
NOMESCO Finland
Hepatoportoenterostomy
+∞
7.3
7
*
K76.4
ICD-10 Finland
Peliosis hepatis
+∞
7.3
7
*
Q44.21
ICD-10 Finland
Atresia of extrahepatic bile ducts
+∞
7.3
7
*
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
9.4
7.3
14
15
D50
ICD-10 Finland
Iron deficiency anaemia
3.9
7.3
28
73
D70.89
ICD-10 Finland
Neutropenic splenomegaly
4.5
7.3
24
54
S82.6
ICD-10 Finland
Fracture of lateral malleolus
2.2
7.2
73
348
R93.2
ICD-10 Finland
Abnormal findings on diagnostic imaging of liver and biliary tract
7.3
7.2
16
22
K42.1
ICD-10 Finland
Umbilical hernia with gangrene
30.2
7.1
9
*
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
4.2
7.1
25
60
TPH00
NOMESCO Finland
Phlebotomy
8.8
7.0
14
16
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.5
7.0
52
212
162
Kela drug reimbursment
liraglutide
4.5
7.0
23
52
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.4
7.0
55
232
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
0.5
7.0
42
879
D07AC01
ATC
betamethasone; topical
1.4
6.9
378
2911
T89
ICPC
Diabetes insulin dependent
2.6
6.9
48
188
K92.9
ICD-10 Finland
Disease of digestive system, unspecified
7.6
6.9
15
20
B02AA02
ATC
tranexamic acid; systemic
1.8
6.9
125
740
A02BC05
ATC
esomeprazole; systemic
1.4
6.9
451
3589
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
13.8
6.9
11
8
C10AA05
ATC
atorvastatin; oral
0.7
6.9
302
3913
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
3.3
6.9
32
98
K05.31
ICD-10 Finland
Periodontitis pronounced
1.8
6.9
128
762
RS230
NOMESCO Finland
NA
8.3
6.8
14
17
TQW11
NOMESCO Finland
Vacuum treatment of wound
3.5
6.8
29
83
N05CF02
ATC
zolpidem; oral
1.6
6.8
185
1226
K65.9
ICD-10 Finland
Peritonitis, unspecified
11.0
6.8
12
11
A10BK03
ATC
empagliflozin; oral
1.9
6.8
93
499
3A064
NOMESCO Finland
NA
9.4
6.8
13
14
318
Kela drug reimbursment
Teriparatide
9.4
6.8
13
14
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.4
6.8
52
218
C61
ICD-10 Finland
Malignant neoplasm of prostate
0.5
6.8
46
923
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.5
6.7
49
200
JJ3AT
NOMESCO Finland
Cytology of liver with ultrasound guidance
16.8
6.7
10
6
602
Kela drug reimbursment
Children's severe malnutrition
16.8
6.7
10
6
SPAT1281
SPAT
Other administrative function
2.0
6.7
87
459
D07XC01
ATC
betamethasone, combinations; topical
1.7
6.7
137
842
WX419
NOMESCO Finland
Other general anesthesy
4.7
6.7
21
45
A02BD07
ATC
lansoprazole, amoxicillin and clarithromycin; systemic
2.1
6.7
69
331
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
6.7
78
394
A08
ICPC
Swelling
2.6
6.7
47
187
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
22.6
6.7
9
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.5
6.7
22
50
N30.0
ICD-10 Finland
Acute cystitis
1.8
6.6
121
718
N05BB01
ATC
hydroxyzine; systemic
2.1
6.6
69
334
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.4
6.6
53
226
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
5.9
6.6
17
29
B01AB10
ATC
tinzaparin; parenteral
2.0
6.6
77
389
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
6.6
214
1484
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
6.6
257
1855
A07EA06
ATC
budesonide; oral, local oral
2.7
6.6
42
157
A40.9
ICD-10 Finland
Streptococcal sepsis, unspecified
10.1
6.5
12
12
H05AA02
ATC
teriparatide; parenteral
10.1
6.5
12
12
S76
ICPC
Skin infection other
2.3
6.5
58
262
D23
ICPC
Hepatomegaly
70.1
6.4
7
*
4AA09
NOMESCO Finland
NA
70.1
6.4
7
*
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
7.4
6.4
14
19
S01.0
ICD-10 Finland
Open wound of scalp
1.8
6.4
99
556
Z71.4
ICD-10 Finland
Alcohol abuse counselling and surveillance
6.6
6.3
15
23
UJF02
NOMESCO Finland
Peroral enteroscopy
6.6
6.3
15
23
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.3
335
2562
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
8.2
6.3
13
16
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
0.4
6.3
21
547
M01AH05
ATC
etoricoxib; oral
0.7
6.3
461
5536
PHM99
NOMESCO Finland
Endovenous obliteration of other vein
+∞
6.3
6
*
TPH10
NOMESCO Finland
Sclerotherapy of varicose veins
+∞
6.3
6
*
PHD77
NOMESCO Finland
Resection of short saphenous vein
+∞
6.3
6
*
45299
ICD-8 Finland
Portal vein thrombosis
+∞
6.3
6
*
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
+∞
6.3
6
*
45600
ICD-8 Finland
Varicose veins of other sites, Of oesophagus
+∞
6.3
6
*
PHD78
NOMESCO Finland
Resection of communicating veins of lower leg and thigh
+∞
6.3
6
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
4.8
6.2
19
40
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
7.1
6.2
14
20
N05AB01
ATC
dixyrazine; systemic
3.6
6.2
26
74
A10AB06
ATC
insulin glulisine; parenteral
5.1
6.2
18
36
N18.8
ICD-10 Finland
Other chronic renal failure
2.6
6.2
42
166
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.0
6.2
74
378
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
7.7
6.1
13
17
F05.9
ICD-10 Finland
Delirium, unspecified
3.0
6.1
32
108
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
12.6
6.1
10
8
W19
ICD-10 Finland
Unspecified fall
1.8
6.0
107
629
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
10.1
6.0
11
11
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.0
576
4850
Mortality – FinRegistry
↥Association
Association between endpoint I9_VARICVEOES and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_VARICVEOES | 8.066 [6.74, 9.65] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.022 |
During the follow-up period (1.1.1998 — 31.12.2019), 1624 out of 2914 females with I9_VARICVEOES died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_VARICVEOES | 9.18 [7.92, 10.63] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 3955 out of 6272 males with I9_VARICVEOES died.
Mortality risk
Mortality risk for people of age
years, who have I9_VARICVEOES.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.878% | 1.631% |
| 5 | 4.186% | 9.69% |
| 10 | 10.017% | 21.728% |
| 15 | 18.217% | 37.731% |
| 20 | 30.053% | 54.018% |
Relationships between endpoints
↥Index endpoint: I9_VARICVEOES – Oesophageal varices
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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