This is a non-core endpoint: only basic statistics are computed.
Defect, injury or illness of lumbar spine
Z21_DEFECT_INJURY_ILLNE_LUMBAR_SPINE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
130 |
4. Check minimum number of eventsNone |
130 |
5. Include endpointsNone |
130 |
6. Filter based on genotype QC (FinnGen only) |
122 |
Control definitions (FinnGen only)
- Control exclude
- Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Z[AB]
Similar endpoints
↥List of similar endpoints to
Defect, injury or illness of lumbar spine
based on the number of shared cases.
Similar with more cases:
- Additional codes for the location of defect, injury or illness
- Factors influencing health status and contact with health services
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 122 | 80 | 42 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | 43.79 | 40.79 | 49.50 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 130
- Matched controls
- 1300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZA8.4
ICD-10 Finland
Fault, injury or disease in the lumbar spine
+∞
185.6
130
*
Z20.9
ICD-10 Finland
Contact with and exposure to unspecified communicable disease
55.6
92.7
57
18
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
17.1
61.3
72
88
Z25.1
ICD-10 Finland
Need for immunization against influenza
23.1
46.3
37
22
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
12.5
34.0
39
43
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
8.4
27.4
45
77
M54.5
ICD-10 Finland
Low back pain
6.4
23.0
92
357
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
16.8
16.4
26
19
Z29.8
ICD-10 Finland
Other specified prophylactic measures
17.0
15.3
24
17
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
27.5
14.3
19
8
ZXA05
NOMESCO Finland
Left side
4.5
14.0
46
142
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
5.1
11.5
28
67
ZXA00
NOMESCO Finland
Right side
3.8
11.4
47
168
M03BC01
ATC
orphenadrine (citrate); systemic
3.4
10.1
55
233
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.3
9.9
30
85
M54.4
ICD-10 Finland
Lumbago with sciatica
3.6
9.8
41
146
R39.1
ICD-10 Finland
Other difficulties with micturition
19.4
9.6
14
8
R4110, ,
SPAT
5.0
9.6
23
54
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.0
9.4
32
99
N03AX16
ATC
[U] pregabalin
3.5
8.9
39
143
IHA10, ,
SPAT
21.8
8.6
12
6
Z71.8
ICD-10 Finland
Other specified counselling
3.0
8.6
61
296
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
4.8
8.6
21
50
IHA10
NOMESCO Finland
Structured mapping of problematic alcohol use
+∞
8.4
8
*
M79.6
ICD-10 Finland
Pain in limb
2.9
8.3
71
380
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.6
8.2
21
52
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.6
8.1
31
103
R07.0
ICD-10 Finland
Pain in throat
5.1
7.9
18
40
Z20.8
ICD-10 Finland
Contact with and exposure to other communicable diseases
3.9
7.6
25
75
N02AX02
ATC
tramadol; systemic, rectal
2.8
7.5
66
353
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
17.0
7.4
11
7
Z00.0
ICD-10 Finland
General medical examination
3.1
7.3
37
146
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.5
7.3
30
104
Z01.8
ICD-10 Finland
Other specified special examinations
3.0
7.1
40
168
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
42.3
6.8
8
*
M01AB05
ATC
diclofenac; systemic, rectal
2.9
6.4
100
694
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
3.0
6.1
31
122
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
39
6.23
11.29
2.6
1.3
—
—
—
0
0
18
16
12.85
10.44
1.6
1.3
6.38
7.35
mmol/l
0.85
18
16
64
316
3.02
8.78
3.5
2.6
—
—
—
0
0
15
20
8.32
7.13
1.7
2.0
—
—
—
0
0
64
353
2.60
6.65
9.7
9.4
1.11
1.15
inr
0.18
26
115
6
0
+∞
6.29
1.0
0.0
8.08
—
mmol/l
—
6
0
50
263
2.46
5.55
4.1
3.4
0.00
0.00
estimate
-0.00
19
95
56
331
2.22
4.59
1.9
1.7
99.47
96.55
pmol/l
0.22
42
161
63
395
2.15
4.41
3.7
3.1
—
—
—
0
0
48
303
1.93
3.07
2.8
2.8
22.00
20.06
ng/l
0.13
17
167
122
1084
3.04
3.04
19.2
10.5
20.02
20.64
mg/l
0.08
108
817
71
511
1.86
3.00
4.0
3.2
0.00
0.00
estimate
-0.00
16
95
69
504
1.79
2.68
5.1
4.5
0.00
0.00
estimate
-0.00
19
100
6
11
5.66
2.57
1.8
1.6
7.20
8.99
mmol/l
—
6
11
8
21
3.99
2.50
1.4
1.2
—
—
—
0
0
7
18
4.05
2.28
1.3
1.3
—
—
—
0
0
67
506
1.67
2.17
3.8
3.2
0.00
0.00
estimate
-0.00
19
104
41
271
1.75
2.16
1.9
1.5
—
—
—
0
0
92
758
1.73
2.11
7.9
6.8
72.21
74.18
u/l
0.23
92
705
8
28
2.98
1.89
1.4
1.6
19.40
26.27
u/l
—
8
23
24
142
1.85
1.80
3.0
2.7
9.50
166.97
ng/l
—
10
88
0
47
0.00
1.74
0.0
1.5
—
—
—
0
0
12
56
2.26
1.67
1.7
1.6
—
—
—
0
0
116
1048
1.99
1.66
16.4
10.2
139.33
139.74
mmol/l
1.57
116
1014
115
1048
1.84
1.42
16.3
10.3
3.93
3.93
mmol/l
0.01
115
1008
7
29
2.49
1.41
2.9
2.4
42.21
45.67
%
—
7
29
6
23
2.68
1.38
1.2
1.0
—
—
—
0
0
21
130
1.73
1.37
2.1
2.5
0.81
0.83
mmol/l
0.40
21
124
35
256
1.50
1.18
2.5
2.5
0.13
0.53
e6/l
1.67
30
188
0
33
0.00
1.18
0.0
1.3
—
—
—
0
0
8
40
2.06
1.14
1.3
1.9
—
—
—
0
0
6
124
0.46
1.12
1.2
1.5
—
—
—
0
0
30
217
1.50
1.06
1.6
1.7
1.32
0.73
mg/l
0.27
21
167
27
199
1.45
0.88
1.4
1.3
37.34
23.62
iu/ml
—
7
66
20
139
1.52
0.85
1.6
1.7
367.86
434.04
pmol/l
0.83
14
125
6
31
1.98
0.85
1.0
1.3
32.83
33.58
nmol/l
—
6
31
6
31
1.98
0.85
1.2
2.6
—
—
—
0
0
6
33
1.86
0.80
3.7
5.4
26.35
24.22
mmol/l
—
6
33
96
879
1.35
0.76
3.1
3.6
—
—
—
0
0
9
58
1.59
0.71
2.6
2.7
6.44
5.70
kpa
—
9
58
5
26
1.96
0.71
1.0
1.5
—
—
—
0
0
41
337
1.32
0.70
2.8
2.8
25.29
29.60
u/l
1.15
41
318
6
102
0.57
0.65
4.8
4.8
—
—
—
0
0
25
194
1.36
0.62
1.2
1.3
97.30
10.41
u/ml
0.49
16
82
16
217
0.70
0.61
1.7
2.0
—
—
—
0
0
8
121
0.64
0.58
2.1
2.1
2.63
6.95
umol/l
—
8
101
29
350
0.78
0.52
4.5
4.1
35.62
36.49
g/l
0.38
29
331
11
77
1.47
0.47
1.0
1.0
—
—
—
0
0
14
105
1.37
0.43
1.2
1.3
545.03
164.98
iu/ml
—
6
37
0
15
0.00
0.41
0.0
1.6
—
3.98
—
0
15
0
18
0.00
0.40
0.0
1.2
—
3.80
—
0
5
6
42
1.45
0.36
11.0
9.2
24.53
25.34
mmol/l
—
6
37
10
133
0.73
0.35
1.8
1.8
—
—
—
0
0
11
82
1.37
0.35
5.9
5.4
105.64
104.22
mmol/l
0.66
11
82
6
45
1.35
0.34
2.2
1.3
—
—
—
0
0
33
288
1.20
0.33
1.3
1.3
0.62
1.28
u/ml
1.17
17
76
13
164
0.77
0.33
3.6
3.4
22.08
21.84
%
—
6
64
10
77
1.32
0.27
6.6
6.1
5.49
5.15
kpa
—
10
72
10
77
1.32
0.27
6.7
6.1
12.72
12.81
kpa
—
10
72
27
237
1.18
0.26
2.1
2.1
—
—
—
0
0
5
40
1.26
0.22
2.4
2.5
—
—
—
0
0
5
40
1.26
0.22
2.0
2.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
99.60
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
3.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
6
48
1.26
0.20
2.7
1.8
—
—
—
0
0
20
226
0.86
0.19
1.8
1.9
—
—
—
0
0
5
65
0.76
0.17
2.0
1.4
—
—
—
0
0
11
127
0.85
0.13
2.5
2.2
12.85
14.84
umol/l
0.24
11
115
25
271
0.90
0.13
1.6
1.6
1.50
1.42
mmol/l
0.19
25
241
5
44
1.14
0.10
4.2
3.3
23.98
24.85
mmol/l
—
5
44
5
61
0.81
0.08
1.6
1.8
—
—
—
0
0
6
73
0.81
0.08
1.2
1.5
—
—
—
0
0
6
74
0.80
0.08
1.5
3.3
4.10
4.72
pmol/l
—
6
63
27
256
1.07
0.07
2.0
1.4
—
—
—
0
0
20
213
0.93
0.06
1.7
1.9
3.58
2.87
mg/l
0.71
20
183
10
91
1.11
0.04
2.4
1.8
350.30
398.64
nmol/l
—
10
84
10
91
1.11
0.04
5.7
5.9
1.03
1.06
mmol/l
—
10
83
14
149
0.93
0.03
1.6
1.6
—
—
—
0
0
14
133
1.06
0.01
1.4
1.8
—
—
—
0
0
49
492
0.99
0.00
2.3
2.2
—
—
—
0
0
12
115
1.05
0.00
2.6
2.1
2.53
2.54
g/l
0.02
12
103
0
5
0.00
-0.00
0.0
1.0
—
58.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
73
0.96
-0.00
3.4
2.9
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
10.60
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
88.80
—
0
5
8
84
0.95
-0.00
1.1
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.35
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
59.13
—
0
8
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
11.60
—
0
5
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
5
51
0.98
-0.00
2.8
1.4
—
—
—
0
0
8
80
1.00
-0.00
1.1
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: Z21_DEFECT_INJURY_ILLNE_LUMBAR_SPINE – Defect, injury or illness of lumbar spine
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).