This is a non-core endpoint: only basic statistics are computed.
Defect, injury or illness of lumbar spine
Z21_DEFECT_INJURY_ILLNE_LUMBAR_SPINE
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
126 |
4. Check minimum number of eventsNone |
126 |
5. Include endpointsNone |
126 |
6. Filter based on genotype QC (FinnGen only) |
126 |
Control definitions (FinnGen only)
- Control exclude
- Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- Z[AB]
Similar endpoints
↥List of similar endpoints to
Defect, injury or illness of lumbar spine
based on the number of shared cases.
Similar with more cases:
- Additional codes for the location of defect, injury or illness
- Factors influencing health status and contact with health services
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 126 | 84 | 42 |
| Unadjusted period prevalence (%) | 0.03 | 0.03 | 0.02 |
| Median age at first event (years) | 43.03 | 39.80 | 49.50 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 113
- Matched controls
- 1132
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZA8.4
ICD-10 Finland
Fault, injury or disease in the lumbar spine
+∞
163.0
113
*
Z20.9
ICD-10 Finland
Contact with and exposure to unspecified communicable disease
63.1
47.3
54
16
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
20.8
40.6
68
76
M54.5
ICD-10 Finland
Low back pain
6.8
20.1
75
254
Z25.1
ICD-10 Finland
Need for immunization against influenza
16.1
20.0
33
28
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
9.3
16.7
37
56
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
7.4
12.8
32
57
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
14.9
12.2
20
16
ZXA05
NOMESCO Finland
Left side
5.1
11.4
41
114
M03BC01
ATC
orphenadrine (citrate); systemic
4.2
10.6
50
180
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
11.5
9.4
17
17
R39.1
ICD-10 Finland
Other difficulties with micturition
97.0
8.5
9
*
ZXA00
NOMESCO Finland
Right side
3.7
8.1
41
150
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.5
7.8
29
81
M79.6
ICD-10 Finland
Pain in limb
3.2
7.7
55
260
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
17.2
7.4
11
7
N02AX02
ATC
tramadol; systemic, rectal
3.1
7.4
54
258
M01AB05
ATC
diclofenac; systemic, rectal
3.2
7.0
87
579
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
4.5
7.0
25
67
IHA10
SPAT
NA
24.2
6.8
9
*
R4110
SPAT
NA
11.0
6.7
12
12
M54.9
ICD-10 Finland
Dorsalgia, unspecified
4.2
6.3
24
68
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
3.8
6.3
27
86
Z00.0
ICD-10 Finland
General medical examination
3.4
6.1
32
117
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
21
37
6.61
11.92
2.6
1.3
—
—
—
0
0
15
20
8.38
10.80
1.7
2.0
—
—
—
0
0
63
299
3.21
9.51
3.4
2.6
—
—
—
0
0
6
0
+∞
6.30
1.0
0.0
8.08
—
mmol/l
—
6
0
50
256
2.58
5.98
4.1
3.3
0.00
0.00
estimate
0.00
19
92
63
381
2.31
5.03
3.7
3.1
—
—
—
0
0
54
315
2.25
4.61
1.9
1.7
100.72
96.59
pmol/l
0.34
41
158
85
1037
0.45
4.06
8.4
10.8
41.59
40.63
%
0.67
73
858
70
493
1.94
3.31
4.0
3.2
0.00
0.00
estimate
0.00
16
92
47
289
2.00
3.30
2.9
2.8
22.00
19.46
ng/l
0.18
17
155
68
486
1.87
2.97
5.1
4.5
0.00
0.00
estimate
0.00
19
97
118
1049
2.97
2.90
18.8
10.5
19.93
20.28
mg/l
0.04
106
789
8
21
3.99
2.51
1.4
1.2
—
—
—
0
0
66
488
1.74
2.41
3.8
3.1
0.00
0.00
estimate
—
9
97
7
17
4.29
2.39
1.3
1.3
—
—
—
0
0
88
724
1.71
2.02
7.8
6.8
72.50
74.14
u/l
0.18
88
674
40
268
1.72
2.01
1.9
1.5
—
—
—
0
0
8
28
2.98
1.90
1.4
1.6
19.40
26.27
u/l
—
8
23
0
47
0.00
1.74
0.0
1.5
—
—
—
0
0
112
1011
1.97
1.60
15.8
10.1
139.30
139.75
mmol/l
1.66
112
978
7
27
2.68
1.54
2.9
2.3
42.21
47.81
%
—
7
27
108
975
1.75
1.39
3.8
3.2
1.41
1.28
mmol/l
0.82
108
908
111
1011
1.82
1.37
15.6
10.2
3.93
3.93
mmol/l
0.00
111
973
20
123
1.74
1.34
2.2
2.5
0.81
0.83
mmol/l
0.52
20
117
34
241
1.56
1.33
2.5
2.4
0.14
0.54
e6/l
1.61
29
180
11
56
2.06
1.26
1.7
1.6
—
—
—
0
0
21
134
1.68
1.24
2.7
2.7
9.86
177.15
ng/l
—
7
82
0
33
0.00
1.18
0.0
1.3
—
—
—
0
0
29
208
1.51
1.07
1.6
1.7
1.36
0.74
mg/l
0.27
20
160
27
196
1.48
0.95
1.4
1.2
37.34
24.82
iu/ml
—
7
61
6
29
2.12
0.90
1.5
2.8
—
—
—
0
0
109
1014
1.56
0.90
4.0
3.6
1.40
1.48
mmol/l
1.34
109
949
110
1026
1.57
0.89
4.1
3.8
2.84
2.89
mmol/l
0.29
110
958
6
31
1.98
0.85
1.0
1.3
32.83
33.58
nmol/l
—
6
31
109
1017
1.53
0.85
4.3
3.6
4.71
4.79
mmol/l
0.41
109
956
7
124
0.54
0.83
1.3
1.5
—
—
—
0
0
5
23
2.22
0.77
1.0
1.0
—
—
—
0
0
25
189
1.40
0.72
1.2
1.3
97.30
10.38
u/ml
0.49
16
79
5
26
1.96
0.71
1.0
1.5
—
—
—
0
0
26
331
0.73
0.69
4.5
4.1
35.92
36.47
g/l
0.20
26
313
18
130
1.45
0.66
1.7
1.7
363.08
427.79
pmol/l
0.74
13
117
16
217
0.70
0.62
1.7
2.0
—
—
—
0
0
93
861
1.31
0.61
3.0
3.6
—
—
—
0
0
7
111
0.61
0.61
1.7
2.1
2.57
7.21
umol/l
—
7
94
84
770
1.27
0.59
2.6
2.7
34.11
38.69
u/l
0.59
84
738
6
35
1.75
0.58
1.2
2.0
—
—
—
0
0
8
54
1.51
0.58
2.3
2.8
6.17
5.69
kpa
—
8
54
39
327
1.28
0.57
2.8
2.8
24.56
29.44
u/l
1.45
39
308
6
98
0.59
0.54
4.8
4.9
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
3.80
—
0
5
5
36
1.40
0.38
2.0
2.4
—
—
—
0
0
5
36
1.40
0.38
2.4
2.6
—
—
—
0
0
6
41
1.49
0.36
11.0
9.4
24.53
25.34
mmol/l
—
6
36
10
133
0.73
0.35
1.8
1.9
—
—
—
0
0
6
43
1.41
0.35
2.2
1.3
—
—
—
0
0
13
164
0.77
0.33
3.6
3.5
22.08
21.84
%
—
6
64
10
75
1.36
0.31
1.0
1.0
—
—
—
0
0
13
103
1.29
0.29
1.2
1.3
545.03
164.98
iu/ml
—
6
37
9
73
1.25
0.26
6.7
6.3
5.43
5.15
kpa
—
9
68
27
237
1.18
0.26
2.1
2.1
—
—
—
0
0
31
278
1.15
0.23
1.3
1.3
0.62
1.29
u/ml
1.17
17
74
0
11
0.00
0.21
0.0
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
6
48
1.26
0.20
2.7
1.8
—
—
—
0
0
27
242
1.15
0.20
2.7
2.0
103.81
225.02
u/l
0.91
27
229
19
213
0.87
0.16
1.6
1.9
—
—
—
0
0
6
78
0.76
0.16
1.0
1.6
—
—
—
0
0
19
210
0.89
0.13
1.7
1.9
3.72
2.88
mg/l
0.89
19
181
27
252
1.09
0.10
2.0
1.4
—
—
—
0
0
24
258
0.91
0.10
1.6
1.6
1.53
1.42
mmol/l
0.26
24
231
13
145
0.88
0.10
1.5
1.6
—
—
—
0
0
5
61
0.81
0.08
1.6
1.8
—
—
—
0
0
6
72
0.83
0.08
1.5
3.3
4.10
4.73
pmol/l
—
6
61
6
73
0.81
0.08
1.2
1.5
—
—
—
0
0
6
74
0.80
0.08
1.0
1.6
—
—
—
0
0
9
87
1.04
0.07
6.1
6.1
1.02
1.05
mmol/l
—
9
79
10
90
1.12
0.05
2.4
1.8
350.30
397.64
nmol/l
—
10
83
10
109
0.91
0.04
2.4
2.1
2.65
2.54
g/l
—
10
98
48
471
1.03
0.02
3.9
3.6
—
—
—
0
0
12
123
0.97
0.00
1.4
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
0.35
—
0
5
7
71
0.99
0.00
3.4
2.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
100.78
—
0
9
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
5
49
1.02
0.00
2.8
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
88.80
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: Z21_DEFECT_INJURY_ILLNE_LUMBAR_SPINE – Defect, injury or illness of lumbar spine
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).