Portal vein thrombosis

I9_PVT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I81
  • Hospital discharge: ICD-9 452
  • Hospital discharge: ICD-8 452
  • Cause of death: ICD-10 I81
  • Cause of death: ICD-9 452
  • Cause of death: ICD-8 452

2 out of 7 registries used, show all original rules.

593

4. Check minimum number of events

None

593

5. Include endpoints

None

593

6. Filter based on genotype QC (FinnGen only)

569

Control definitions (FinnGen only)

Control exclude
I9_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I80-I89
Name in latin
Thrombosis venae portae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3823 1578 2210
Only index persons 3061 1272 1789
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.06
Only index persons 0.06 0.05 0.07
Median age at first event (years)
Whole population 62.20 62.36 62.10
Only index persons 61.19 60.50 61.68

-FinnGen-

Key figures

All Female Male
Number of individuals 569 248 321
Unadjusted period prevalence (%) 0.12 0.09 0.15
Median age at first event (years) 62.74 61.78 63.48

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
593
Matched controls
5930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I81
ICD-10 Finland
Portal vein thrombosis
+∞
307.7
569
*
B01AB05
ATC
enoxaparin; parenteral
7.1
125.7
370
1126
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
1360.6
117.9
111
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.7
116.5
213
404
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
8.5
112.4
176
281
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
27.5
110.2
77
32
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.7
104.3
178
311
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
28.1
104.1
72
29
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
31.3
100.7
67
24
R18
ICD-10 Finland
Ascites
20.8
95.7
75
41
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.4
91.6
328
1114
B01AA03
ATC
warfarin; systemic
5.8
90.8
235
607
JN3AD
NOMESCO Finland
Abdominal CT examination
6.6
87.5
175
355
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
16.8
79.7
69
46
B01AB10
ATC
tinzaparin; parenteral
6.1
69.2
141
287
K83.0
ICD-10 Finland
Cholangitis
25.3
68.7
49
21
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
35.6
67.6
43
13
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
30.1
62.7
42
15
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
602.5
56.6
55
*
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
21.0
56.0
43
22
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
17.5
52.6
44
27
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
12.6
52.3
53
46
Z51.5
ICD-10 Finland
Palliative care
5.6
51.9
113
241
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
15.5
51.6
46
32
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.5
49.7
294
1297
UJK02
NOMESCO Finland
ERCP
11.1
48.2
53
52
K83.1
ICD-10 Finland
Obstruction of bile duct
16.9
48.2
41
26
B01AB04
ATC
dalteparin; parenteral
7.2
47.1
75
117
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
12.3
47.0
48
42
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
8.8
46.9
62
78
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
+∞
46.5
44
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.2
46.2
108
244
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
79.3
45.8
51
7
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.7
45.3
93
187
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.4
45.3
136
376
130
Kela drug reimbursment
Malignant tumour
4.7
45.3
120
301
K92.1
ICD-10 Finland
Melaena
6.3
45.2
83
150
C03DA01
ATC
spironolactone; oral
4.2
44.3
142
412
N02AA05
ATC
oxycodone; systemic
3.7
44.2
182
629
C03CA01
ATC
furosemide; systemic
3.3
43.5
264
1162
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
8.6
42.0
56
71
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
10.4
41.8
48
50
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
12.1
40.9
42
37
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
14.0
39.4
37
28
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
15.4
39.4
35
24
TPH04
NOMESCO Finland
Cathetrisation of vein
3.3
39.3
206
822
JN4AD
NOMESCO Finland
Body CT examination
4.2
38.8
120
337
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
9.5
38.6
47
53
R50.9
ICD-10 Finland
Fever, unspecified
3.7
38.5
149
490
K92.0
ICD-10 Finland
Haematemesis
9.9
37.9
45
49
A06AD11
ATC
lactulose; oral
3.7
37.5
147
487
JAH00
NOMESCO Finland
Laparotomy
7.2
35.4
55
83
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.4
34.7
61
105
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
48.8
34.2
41
9
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
9.7
33.4
40
44
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
95.7
33.1
36
*
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
12.4
32.8
33
28
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.3
32.7
157
587
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
7.5
31.8
47
67
JN4BD
NOMESCO Finland
Extensive body CT
3.8
31.7
113
348
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.7
31.6
346
2003
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.2
31.6
160
616
WW500
NOMESCO Finland
Blood transfusion
5.7
29.8
58
110
TPH07
NOMESCO Finland
Cathetrisation of artery
3.5
29.3
117
388
PHD99
NOMESCO Finland
Resection of other vein
306.3
29.0
29
*
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
+∞
28.4
27
*
J01MA12
ATC
levofloxacin; systemic
3.0
28.3
162
664
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
7.5
28.3
42
60
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
10.8
28.2
31
30
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
27.8
180
789
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
9.9
27.3
32
34
UJF32
NOMESCO Finland
Coloscopy
2.7
26.8
208
997
A10AB05
ATC
insulin aspart; parenteral
4.0
26.6
82
227
C07AG02
ATC
carvedilol; oral
4.2
25.5
74
196
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
7.8
25.3
36
49
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
22.5
25.1
36
17
ZXD05
NOMESCO Finland
Urgent procedure
2.5
24.8
223
1140
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
6.6
24.8
41
66
A10AE04
ATC
insulin glargine; parenteral
3.5
24.6
97
317
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
6.4
24.5
42
70
N02AX02
ATC
tramadol; systemic, rectal
2.4
24.5
313
1873
127
Kela drug reimbursment
Transplant complication
10.1
24.3
28
29
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
70.5
24.0
27
*
A02BC02
ATC
pantoprazole; systemic
2.7
23.9
448
3175
UJF30
NOMESCO Finland
Ileoscopy through colon
3.4
22.6
90
295
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
28.6
22.5
30
11
J01MA02
ATC
ciprofloxacin; systemic
2.3
22.3
271
1568
WX892
NOMESCO Finland
Monitored bed care
3.7
22.2
78
236
A04AA02
ATC
granisetron; systemic, transdermal
3.9
21.8
69
194
A05AA02
ATC
ursodeoxycholic acid; oral
17.4
21.2
33
20
K86.1
ICD-10 Finland
Other chronic pancreatitis
17.4
21.2
33
20
B01AF02
ATC
apixaban; oral
3.0
21.1
104
387
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.6
21.0
52
121
K86.3
ICD-10 Finland
Pseudocyst of pancreas
38.7
20.9
26
7
L01BC06
ATC
capecitabine; oral
4.8
20.7
48
106
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
26.6
20.6
28
11
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
7.6
20.1
29
40
Z94.4
ICD-10 Finland
Liver transplant status
59.7
20.0
23
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.6
20.0
136
600
C07AA05
ATC
propranolol; systemic
2.5
19.9
151
702
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.4
19.6
52
128
XF400
NOMESCO Finland
ECG with 12 standard connections
2.6
19.4
130
569
ZX120
NOMESCO Finland
Intravenous
3.2
19.0
84
293
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.6
19.0
37
70
A41.9
ICD-10 Finland
Sepsis, unspecified
5.2
18.8
40
82
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
16.9
18.5
29
18
H02AB02
ATC
dexamethasone; systemic
2.9
18.4
100
392
L04AA06
ATC
mycophenolic acid; systemic
7.4
18.4
27
38
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
4.0
18.3
54
144
PHD76
NOMESCO Finland
Resection of long saphenous vein
+∞
17.8
17
*
K76.6
ICD-10 Finland
Portal hypertension
+∞
17.8
17
*
45299
ICD-8 Finland
Portal vein thrombosis
+∞
17.8
17
*
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
+∞
17.8
17
*
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
+∞
17.8
17
*
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
4.4
17.8
46
111
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.3
17.6
47
116
WX002
NOMESCO Finland
Sedation and analgesia
2.4
17.6
143
683
K94
ICPC
Phlebitis/thrombophlebitis
24.9
17.4
24
10
R10.0
ICD-10 Finland
Acute abdomen
5.4
17.4
35
68
103
Kela drug reimbursment
Diabetes, insulin-treated
2.2
17.3
201
1117
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.4
17.1
65
206
L01XX05
ATC
hydroxycarbamide; oral
7.4
17.1
25
35
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.0
16.9
84
313
D64.9
ICD-10 Finland
Anaemia, unspecified
2.8
16.8
91
355
K76.9
ICD-10 Finland
Liver disease, unspecified
15.7
16.8
27
18
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.9
16.7
26
39
JJC00
NOMESCO Finland
Allogenic transplantation of liver
92.7
16.6
18
*
UJD02
NOMESCO Finland
Gastroscopy
3.9
16.5
50
136
K85
ICD-10 Finland
Acute pancreatitis
6.5
16.4
27
43
Z3231
NOMESCO Finland
Registered nurse
2.2
16.2
185
1017
JN4CD
NOMESCO Finland
Very extensive body CT
4.2
16.1
45
115
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
16.1
181
989
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
17.8
15.7
24
14
K81.0
ICD-10 Finland
Acute cholecystitis
5.8
15.7
29
52
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
15.7
15
*
Z2221
NOMESCO Finland
Medical doctor
2.2
15.7
179
982
D68.8
ICD-10 Finland
Other specified coagulation defects
22.8
15.6
22
10
WZC30
NOMESCO Finland
Teaching
2.4
15.6
122
570
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
15.5
62
203
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.6
15.4
37
84
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
12.2
15.2
27
23
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
24.1
15.2
21
9
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
4.1
15.1
42
107
WZC00
NOMESCO Finland
Treatment plan or consultation
2.0
15.0
225
1365
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.4
14.9
57
181
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
21.7
14.7
21
10
R4110
NOMESCO Finland
Physiotherapy
2.1
14.7
187
1065
A46
ICD-10 Finland
Erysipelas
2.6
14.7
98
424
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
13.8
14.3
24
18
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
14.3
175
981
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.2
14.3
60
202
XW000
NOMESCO Finland
Bone marrow biopsy
3.8
14.1
44
122
R4190
NOMESCO Finland
Nutritional therapy
4.1
14.1
39
99
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
16.3
14.0
22
14
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
54.7
13.9
16
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.6
13.9
47
138
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
13.7
91
392
JFB00
NOMESCO Finland
Partial resection of small intestine
6.7
13.7
22
34
D45
ICD-10 Finland
Polycythaemia vera
11.3
13.6
25
23
4520A
ICD-9 Finland
Portal vein thrombosis[THROMBOSIS VENAE PORTAE]
+∞
13.6
13
*
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
13.2
13.5
23
18
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
143.2
13.5
14
*
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
18.8
13.4
20
11
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
21.8
13.4
19
9
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
13.4
77
309
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
10.8
13.4
25
24
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.7
13.2
31
69
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.3
13.1
116
569
TQW11
NOMESCO Finland
Vacuum treatment of wound
5.4
13.1
26
50
UJF92
NOMESCO Finland
Capsular endoscopy
6.3
13.0
22
36
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
51.2
12.9
15
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.4
12.9
33
79
P01AB01
ATC
metronidazole; oral, rectal
1.9
12.8
243
1580
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
12.6
12.7
22
18
Z3226
NOMESCO Finland
Physiotherapist
2.2
12.6
122
620
I86.4
ICD-10 Finland
Gastric varices
+∞
12.5
12
*
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
12.5
12
*
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
132.7
12.5
13
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
12.4
61
225
ZXE40
NOMESCO Finland
More than seven and less than nine hours
5.5
12.4
24
45
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
4.0
12.4
36
95
A04AA01
ATC
ondansetron; systemic, rectal
2.8
12.3
64
243
AA1AD
NOMESCO Finland
CT of head and brain
2.0
12.3
176
1036
WX402
NOMESCO Finland
General anaesthesia
2.1
12.1
139
756
WX882
NOMESCO Finland
High dependency care
4.3
11.9
31
75
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.7
11.9
38
107
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
12.0
11.9
21
18
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.5
11.8
82
360
K72.0
ICD-10 Finland
Acute and subacute hepatic failure
66.3
11.6
13
*
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
66.3
11.6
13
*
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
66.3
11.6
13
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.2
11.5
31
77
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
4.7
11.5
27
60
A41.8
ICD-10 Finland
Other specified sepsis
5.0
11.5
25
52
L04AD02
ATC
tacrolimus; systemic
14.0
11.5
19
14
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
11.5
168
993
K76.7
ICD-10 Finland
Hepatorenal syndrome
+∞
11.5
11
*
L04AX01
ATC
azathioprine; systemic
3.9
11.5
34
91
JAH01
NOMESCO Finland
Laparoscopy
3.7
11.3
37
106
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
11.3
98
475
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
5.7
11.2
21
38
K29.6
ICD-10 Finland
Other gastritis
10.3
11.1
21
21
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
44.2
11.0
13
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
10.9
111
574
K65.0
ICD-10 Finland
Acute peritonitis
12.2
10.9
19
16
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
15.9
10.9
17
11
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
18.2
10.8
16
9
WPB10
NOMESCO Finland
Making a convalescent care decision
28.6
10.8
14
5
D97
ICPC
Liver disease NOS
28.6
10.8
14
5
A02BC01
ATC
omeprazole; systemic
1.9
10.7
173
1055
ZXE00
NOMESCO Finland
One hour or less
1.8
10.7
230
1534
H02AB09
ATC
hydrocortisone; systemic
4.8
10.6
24
52
SPAT1262
SPAT
Handing over of treatment supplies
2.1
10.5
120
648
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
10.5
167
1013
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
+∞
10.4
10
*
K72.9
ICD-10 Finland
Hepatic failure, unspecified
16.4
10.4
16
10
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
33.2
10.4
13
*
D01
ICPC
Abdominal pain/cramps general
2.5
10.3
71
310
J01DB01
ATC
cefalexin; oral
2.0
10.2
473
3946
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.8
10.0
30
81
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.2
9.9
39
126
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.6
9.9
33
96
EBA15
NOMESCO Finland
Extraction of multiple teeth
3.4
9.9
35
106
L04AD01
ATC
ciclosporin; systemic
5.0
9.9
21
43
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
9.0
9.8
20
23
A07AA11
ATC
rifaximin; oral
26.5
9.8
13
5
SPAT1255
SPAT
Intravenous administration of medicine
2.8
9.7
49
183
JMA10
NOMESCO Finland
Transabdominal total splenectomy
13.7
9.7
16
12
UJK12
NOMESCO Finland
Peroral cholangioscopy
55.9
9.7
11
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
11.6
9.6
17
15
E13.8
ICD-10 Finland
Other specified diabetes mellitus, with unspecified complications
101.6
9.4
10
*
198
Kela drug reimbursment
Sorafenib
30.6
9.4
12
*
ZX112
NOMESCO Finland
Subcutaneous
4.5
9.4
23
53
J01FF01
ATC
clindamycin; systemic
1.8
9.4
162
1003
TK800
NOMESCO Finland
Hemodialysis
4.6
9.4
22
49
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.5
9.3
61
260
R60.0
ICD-10 Finland
Localized oedema
2.3
9.2
74
346
TPH00
NOMESCO Finland
Phlebotomy
15.9
9.1
14
9
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
9.0
213
1446
JLC30
NOMESCO Finland
Pancreatoduodenectomy
18.9
9.0
13
7
K85.8
ICD-10 Finland
Other acute pancreatitis
12.8
8.9
15
12
A02BC05
ATC
esomeprazole; systemic
1.7
8.9
243
1715
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
9.7
8.8
17
18
TKC20
NOMESCO Finland
Catheterisation of bladder
2.6
8.7
51
206
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
50.8
8.7
10
*
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
8.7
122
705
K29
ICPC
Cardiovascular sympt/complt other
3.5
8.6
30
90
TJA10
NOMESCO Finland
Laparocentesis
28.0
8.5
11
*
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
20.4
8.5
12
6
J81
ICD-10 Finland
Pulmonary oedema
20.4
8.5
12
6
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.9
8.5
41
150
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
13.0
8.4
14
11
T90
ICPC
Diabetes non-insulin dependent
1.8
8.4
152
952
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.1
8.3
34
113
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
14.7
8.2
13
9
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
8.2
219
1527
Z2446
NOMESCO Finland
Social worker
2.6
8.2
48
194
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.5
8.2
20
46
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.1
8.2
34
114
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
4.9
8.2
18
38
K99
ICPC
Cardiovascular disease other
4.1
8.1
22
55
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.1
8.1
33
109
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.2
8.1
75
372
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
11.9
8.1
14
12
K75.0
ICD-10 Finland
Abscess of liver
33.8
8.1
10
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
8.1
84
436
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
22.4
8.0
11
5
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
22.4
8.0
11
5
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.5
7.9
50
210
A10AC01
ATC
insulin (human); parenteral
2.4
7.9
53
229
A10AE05
ATC
insulin detemir; parenteral
2.7
7.9
42
162
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.0
7.8
34
117
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
3.0
7.8
34
117
8140/3-C25.9
ICD-O-3
Adenocarcinoma, NOS, of pancreas, NOS
11.0
7.8
14
13
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
11.0
7.8
14
13
N05CF01
ATC
zopiclone; oral
1.7
7.8
193
1316
WX872
NOMESCO Finland
Intensive care
2.7
7.8
41
157
K29.7
ICD-10 Finland
Gastritis, unspecified
3.3
7.8
29
91
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.3
7.8
29
91
K51.5
ICD-10 Finland
Left sided colitis
4.0
7.8
22
57
E13
ICD-10 Finland
Other specified diabetes mellitus
15.3
7.7
12
8
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
25.4
7.6
10
*
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.4
7.5
26
78
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
3.8
7.4
22
59
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
7.4
183
1244
WPA10
NOMESCO Finland
Proactive palliative care treatment plan
13.6
7.4
12
9
A02BC03
ATC
lansoprazole; oral
1.7
7.4
170
1135
JKA20
NOMESCO Finland
Cholecystectomy
3.6
7.3
24
69
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
7.0
7.3
17
25
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.5
7.3
25
74
R16.1
ICD-10 Finland
Splenomegaly, not elsewhere classified
+∞
7.3
7
*
I85
ICD-10 Finland
Oesophageal varices
+∞
7.3
7
*
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
4.4
7.3
18
42
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.6
7.3
41
163
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
7.3
89
490
A10BA02
ATC
metformin; oral
1.7
7.2
178
1208
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.5
7.2
46
194
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
20.3
7.2
10
5
N05CD07
ATC
temazepam; oral
2.0
7.1
78
412
R60.9
ICD-10 Finland
Oedema, unspecified
2.8
7.1
36
135
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
12.2
7.1
12
10
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
7.1
290
2227
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
7.1
115
694
N03AX16
ATC
[U] pregabalin
1.7
7.0
139
888
K70.1
ICD-10 Finland
Alcoholic hepatitis
14.0
6.9
11
8
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
9.5
6.8
13
14
JAH33
NOMESCO Finland
Opening of laparostomy
40.5
6.8
8
*
D73.1
ICD-10 Finland
Hypersplenism
40.5
6.8
8
*
E0000UV, ,
ATC
1.6
6.7
219
1588
K55.8
ICD-10 Finland
Other vascular disorders of intestine
22.8
6.7
9
*
S97
ICPC
Chronic ulcer skin
2.5
6.7
41
170
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.5
6.7
41
170
B34.9
ICD-10 Finland
Viral infection, unspecified
3.7
6.6
21
59
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
4.2
6.6
17
41
X59
ICD-10 Finland
Exposure to unspecified factor
1.8
6.6
107
645
SPAT1229
SPAT
Assessment of need for aid
2.4
6.6
43
184
D06
ICPC
Abdominal pain localized other
2.4
6.5
45
198
JK3FT
NOMESCO Finland
Exchange of bile duct catheter with radiological guidance
70.6
6.4
7
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
3.7
6.4
20
56
RD210, ,
NOMESCO Finland
6.1
6.3
16
27
C22.1
ICD-10 Finland
Malignant neoplasm: Intrahepatic bile duct carcinoma
18.2
6.3
9
5
K86.01
ICD-10 Finland
Late effects of pancreatitis caused by alcohol
18.2
6.3
9
5
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
18.2
6.3
9
5
PHE99
NOMESCO Finland
Thrombectomy of other vein
+∞
6.3
6
*
C24.0
ICD-10 Finland
Malignant neoplasm: Extrahepatic bile duct
+∞
6.3
6
*
K65.9
ICD-10 Finland
Peritonitis, unspecified
27.0
6.2
8
*
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
27.0
6.2
8
*
R06AE07
ATC
cetirizine; oral
1.6
6.2
219
1614
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
6.2
105
641
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
7.8
6.1
13
17
D70.82
ICD-10 Finland
Drug-induced neutropenia
4.2
6.1
16
39
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
6.1
81
458
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.9
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
244
424
9.08
147.90
5.0
2.2
0.18
0.22
g/l
9.86
228
397
140
153
11.67
121.07
5.0
2.7
24.23
21.31
s
1.45
119
138
115
112
12.50
107.10
1.3
1.1
81.82
111.67
titre
—
11
6
108
100
12.98
103.84
5.6
2.7
44.79
31.82
umol/l
3.96
100
88
223
534
6.09
94.15
9.0
2.5
14.82
7.61
umol/l
2.64
208
474
111
129
10.36
90.79
6.2
3.3
3.55
3.67
g/l
0.22
106
124
130
196
8.21
86.00
3.5
3.2
482.10
1153.29
u/ml
0.42
117
167
77
59
14.85
82.55
1.2
1.3
3.44
5.41
u/ml
0.47
36
22
200
516
5.34
75.84
5.0
4.2
4.52
39.01
ug/l
1.48
169
439
309
1155
4.50
72.56
13.5
3.9
76.06
90.43
%
14.57
302
1131
453
2262
5.25
71.49
29.6
12.9
1.46
1.24
inr
3.86
134
637
421
2025
4.72
68.82
13.0
4.7
32.57
35.78
g/l
20.80
405
1896
322
1284
4.30
68.19
8.2
4.3
—
—
—
0
0
226
728
4.40
63.45
7.4
2.3
32.33
29.51
s
6.23
221
709
204
615
4.53
62.42
3.9
2.6
22.05
22.66
%
0.21
189
528
457
2475
4.69
60.05
20.9
6.3
18.11
11.84
umol/l
5.13
451
2359
163
430
4.85
58.78
6.5
2.3
431.22
43.72
u/l
0.48
152
365
206
653
4.30
58.49
3.8
2.5
2.21
2.31
g/l
1.25
194
604
227
778
4.11
57.75
8.0
3.8
0.78
0.82
mmol/l
7.29
221
732
325
1487
3.62
52.54
6.5
2.4
58.35
61.53
u/l
0.26
312
1376
208
711
3.97
52.42
3.9
2.5
11.52
13.10
umol/l
2.23
200
665
138
351
4.82
51.57
1.9
2.8
11.50
10.39
g/l
1.64
132
318
122
282
5.19
51.10
1.5
1.9
1.23
1.32
g/l
0.26
117
259
321
1521
3.42
47.82
9.4
3.3
45.31
33.14
u/l
4.13
312
1451
45
36
13.44
46.56
2.0
1.3
—
—
—
0
0
139
406
4.17
42.87
10.6
8.8
8.20
9.92
mmol/l
2.08
134
389
184
657
3.61
42.34
3.0
2.0
—
—
—
0
0
74
133
6.21
40.43
1.5
1.5
193.33
298.15
ug/g
4.06
55
82
144
450
3.91
40.21
1.5
1.6
—
—
—
0
0
150
485
3.80
39.83
1.5
1.6
—
—
—
0
0
432
2677
3.26
36.99
17.6
9.4
4.77
4.10
e9/l
1.03
382
2321
165
601
3.42
36.18
8.4
6.6
1.01
1.05
mmol/l
0.92
156
559
390
2306
3.02
35.84
12.5
7.1
1.20
1.21
mmol/l
2.50
336
1973
374
2162
2.98
35.84
10.5
6.1
2.72
2.95
%
1.37
358
2024
375
2177
2.97
35.54
11.1
6.4
9.26
8.82
%
1.62
359
2039
285
1432
2.91
35.45
6.2
2.5
—
—
—
0
0
366
2106
2.93
35.11
10.5
6.1
0.71
0.67
%
0.45
349
1966
380
2232
2.96
35.05
10.7
6.3
24.23
27.86
%
8.49
363
2096
373
2172
2.93
34.92
11.1
6.5
—
—
—
0
0
375
2193
2.93
34.77
10.0
6.0
59.69
56.93
%
4.13
361
2058
159
583
3.36
34.31
1.4
1.3
458.82
484.83
titre
0.06
34
116
364
2108
2.88
34.15
11.1
6.4
1.20
1.21
mmol/l
3.80
348
1923
382
2298
2.86
32.81
9.9
5.9
0.60
0.60
e9/l
0.10
329
1954
382
2298
2.86
32.81
10.0
5.9
0.04
0.04
e9/l
0.33
329
1963
31
24
13.57
32.51
1.3
1.2
1.10
1.09
ratio
—
11
9
38
41
9.83
32.12
1.3
1.3
—
—
—
0
0
268
1359
2.77
31.95
5.6
4.2
7.40
7.40
ph
0.05
61
252
385
2351
2.82
31.67
10.0
6.0
1.57
1.91
e9/l
7.44
336
2050
387
2371
2.82
31.60
10.4
6.3
0.18
0.20
e9/l
1.85
334
2062
207
956
2.79
29.08
4.3
1.8
2.56
1.13
mg/l
5.20
174
742
352
2131
2.60
28.18
5.6
2.5
—
—
—
0
0
271
1453
2.59
27.96
4.1
3.3
42.41
106.44
e6/l
0.71
221
1105
254
1321
2.61
27.91
3.9
3.2
0.59
0.40
e6/l
0.62
203
988
225
1107
2.66
27.65
6.1
2.4
—
—
—
0
0
417
2776
2.69
26.82
10.4
4.8
7.31
6.74
mmol/l
5.14
408
2608
156
653
2.88
26.03
1.4
1.2
—
—
—
0
0
243
1273
2.54
25.87
3.9
3.2
—
—
—
0
0
496
3668
3.15
24.99
23.7
7.4
122.03
79.16
u/l
15.65
487
3436
115
415
3.20
24.85
11.2
9.9
—
—
—
0
0
219
1113
2.53
24.64
4.0
2.1
4.02
3.04
mg/l
4.32
196
941
139
562
2.92
24.60
3.8
2.8
2.03
1.81
%
1.15
116
512
35
17
21.79
24.16
1.8
2.3
1193.58
6253.90
e6/l
—
19
10
119
446
3.09
24.06
6.0
4.5
1.92
1.87
mmol/l
0.05
95
373
193
936
2.57
23.84
4.1
2.9
578.12
562.34
mosm/kgh2o
0.37
173
807
119
450
3.06
23.67
5.9
4.4
5.65
5.75
kpa
0.46
112
439
72
197
4.02
23.66
2.6
2.0
4.28
2.69
ug/l
0.30
65
180
120
459
3.02
23.37
6.1
4.4
—
7.37
—
0
5
32
14
24.08
22.81
2.0
2.1
—
—
—
0
0
193
967
2.48
21.97
3.4
2.5
6.56
4.43
e6/l
1.17
178
878
46
95
5.17
21.43
1.8
1.2
—
—
—
0
0
127
527
2.79
21.16
10.0
8.3
4.95
5.08
kpa
0.75
122
505
279
1662
2.28
21.15
4.9
3.8
28.82
118.56
e6/l
2.46
228
1189
127
528
2.79
21.07
10.0
8.2
12.21
12.31
kpa
0.07
121
508
300
1872
2.22
19.96
5.2
2.7
205.08
142.25
ug/l
1.96
284
1715
28
13
22.53
19.66
1.6
1.1
8.85
18.54
g/l
—
19
8
84
289
3.22
19.44
1.3
1.4
—
—
—
0
0
28
14
20.92
19.23
3.8
2.3
—
—
—
0
0
28
15
19.53
18.81
1.9
2.4
—
—
—
0
0
107
430
2.82
18.80
4.2
2.7
79.35
70.87
e9/l
1.14
80
332
121
522
2.66
18.51
10.3
8.4
0.57
1.08
mmol/l
0.73
99
420
168
849
2.37
18.29
1.6
1.5
3.40
2.45
g/l
4.81
137
515
67
209
3.49
18.10
2.3
2.0
1.31
1.61
g/l
1.25
60
182
426
3146
2.26
17.56
9.3
3.1
130.40
49.67
u/l
15.32
411
2927
164
837
2.33
17.34
2.9
2.9
1.77
1.05
e6/l
0.70
97
479
157
788
2.35
17.24
3.2
3.1
2.63
1.87
e6/l
0.55
93
433
412
3033
2.17
16.66
5.7
4.2
45.33
2134.49
e6/l
—
6
51
72
249
3.15
16.45
1.3
1.3
—
—
—
0
0
93
383
2.69
15.45
2.6
3.0
65.35
66.87
g/l
0.95
81
357
94
390
2.68
15.38
5.7
3.8
4.50
4.50
kpa
0.00
87
378
31
61
5.31
15.21
1.1
1.1
—
—
—
0
0
102
446
2.55
14.99
1.6
1.4
—
—
—
0
0
33
70
4.93
14.88
1.0
1.1
—
—
—
0
0
164
889
2.17
14.67
4.2
3.8
422.15
462.58
ng/l
0.06
122
701
23
16
14.90
14.16
1.0
1.1
—
—
—
0
0
305
2092
1.94
13.99
22.1
9.4
0.19
0.00
e9/l
0.56
245
1708
33
75
4.60
13.72
1.1
1.2
—
—
—
0
0
216
1328
1.99
13.57
3.5
3.0
—
—
—
0
0
418
3210
2.02
13.53
5.6
4.1
—
—
—
0
0
244
1572
1.94
13.31
5.6
3.4
2.33
2.35
mmol/l
1.04
223
1388
23
19
12.54
13.20
1.0
1.1
—
—
—
0
0
35
92
3.98
12.08
1.5
1.4
324.86
258.94
u/ml
0.52
22
51
35
92
3.98
12.08
1.9
1.4
—
—
—
0
0
189
1148
1.95
12.04
13.6
7.2
—
—
—
0
0
110
548
2.24
11.92
1.5
1.3
—
—
—
0
0
64
249
2.76
11.78
14.6
11.0
—
—
—
0
0
111
561
2.20
11.59
1.7
1.5
—
—
—
0
0
114
588
2.16
11.30
1.7
1.7
—
—
—
0
0
107
541
2.19
11.14
2.1
1.6
—
—
—
0
0
85
398
2.33
10.61
6.5
4.1
0.93
0.81
%
0.25
53
157
27
65
4.30
10.46
1.6
1.4
—
—
—
0
0
74
328
2.44
10.44
7.7
3.9
7.43
7.41
ph
—
7
35
78
355
2.38
10.38
6.6
4.1
0.91
0.48
%
1.30
46
127
265
1863
1.76
10.17
5.0
3.7
30.04
45.76
ng/l
1.02
212
1344
145
859
1.91
9.67
2.0
1.7
1148.74
1181.26
nmol/l
0.15
111
648
79
375
2.28
9.53
6.3
4.1
0.06
0.13
%
0.64
47
134
86
423
2.21
9.52
2.6
2.0
379.73
374.50
nmol/l
0.03
77
387
255
1803
1.73
9.38
3.3
2.3
74.62
77.58
nmol/l
0.95
234
1602
71
324
2.35
9.38
2.0
2.6
—
—
—
0
0
267
1913
1.72
9.35
2.3
2.0
86.98
94.47
pmol/l
2.01
158
1013
17
17
10.26
9.07
1.1
1.5
—
—
—
0
0
19
39
5.00
8.89
1.2
1.2
—
—
—
0
0
24
60
4.13
8.87
2.3
2.8
4.62
94.94
nmol/l
0.50
24
60
56
236
2.52
8.79
2.9
2.8
0.67
0.65
%
0.11
56
236
20
44
4.67
8.65
1.4
1.1
—
—
—
0
0
19
40
4.87
8.64
2.3
2.3
—
—
—
0
0
36
121
3.10
8.61
1.2
1.2
—
—
—
0
0
75
364
2.21
8.56
6.3
4.3
1.23
1.23
mmol/l
0.01
70
324
72
344
2.24
8.54
6.7
4.2
0.05
0.08
%
0.12
39
103
142
880
1.81
8.07
5.8
2.9
2.49
2.45
mmol/l
2.63
125
774
38
139
2.85
7.86
5.4
2.8
—
—
—
0
0
20
48
4.28
7.79
1.4
1.3
—
—
—
0
0
13
11
12.05
7.60
3.2
4.9
—
—
—
0
0
417
3470
1.68
7.52
5.2
3.9
17.18
12.23
mm/h
6.10
390
3190
36
131
2.86
7.52
1.5
1.3
—
—
—
0
0
40
155
2.69
7.44
1.8
2.6
11.39
10.73
g/l
0.29
34
143
14
15
9.53
7.31
2.9
4.5
—
—
—
0
0
183
1257
1.66
7.07
3.9
2.7
2815.89
7746.90
umol/l
1.04
158
1108
23
67
3.53
6.90
2.0
2.0
—
—
—
0
0
246
1830
1.59
6.82
2.6
2.1
—
—
—
0
0
13
15
8.83
6.58
2.0
2.9
38230.77
32100.33
ug/l
0.77
13
15
28
96
3.01
6.51
3.2
3.9
—
—
—
0
0
35
136
2.67
6.49
1.7
2.6
35.82
38.05
g/l
1.09
29
125
10
7
14.50
6.41
1.4
1.4
—
—
—
0
0
21
62
3.47
6.19
6.5
4.6
—
—
—
0
0
26
88
3.04
6.19
1.5
1.3
54.00
66.73
mmol/l
1.07
18
75
29
105
2.85
6.14
4.6
4.5
2.47
2.33
mmol/l
0.10
18
69
28
100
2.89
6.08
1.9
2.2
15.27
16.54
%
0.65
13
47
44
201
2.28
5.82
4.7
2.9
134.77
57.02
u/ml
0.69
44
194
64
340
1.99
5.76
5.4
4.0
87.46
83.27
ng/l
0.12
57
303
140
941
1.64
5.75
1.3
1.2
1.06
1.95
u/ml
0.88
32
243
196
1429
1.56
5.71
2.8
2.1
213.57
253.87
u/l
0.26
191
1352
85
498
1.83
5.70
3.3
2.3
281.68
137.90
ug/g
1.98
78
404
27
98
2.84
5.70
1.3
1.5
—
—
—
0
0
39
171
2.37
5.66
3.6
4.7
0.33
0.35
g/l
0.05
23
77
32
128
2.59
5.63
11.1
6.1
1.98
1.44
mmol/l
0.67
25
110
29
111
2.70
5.56
2.4
3.0
—
—
—
0
0
29
112
2.67
5.47
1.7
1.9
—
—
—
0
0
12
17
7.18
5.46
1.2
1.1
—
—
—
0
0
57
297
2.02
5.42
7.3
4.3
—
—
—
0
0
66
364
1.92
5.34
2.9
3.1
211.35
196.23
ng/l
0.10
60
322
12
18
6.78
5.27
1.0
1.0
—
—
—
0
0
50
252
2.07
5.21
10.0
4.1
—
—
—
0
0
286
2294
1.48
5.14
4.4
3.5
0.00
0.01
estimate
0.50
71
394
160
1141
1.55
5.05
1.9
1.5
21.54
20.53
nmol/l
0.30
149
962
206
1552
1.50
5.03
3.8
3.8
18.08
9.30
mg/mmol
0.81
124
1007
283
2272
1.47
5.03
4.4
3.5
0.00
0.00
estimate
0.50
77
442
197
1471
1.51
5.02
3.4
3.2
1140.39
232.93
mg/l
0.85
125
963
204
1543
1.49
4.86
3.2
3.3
7.57
7.91
mmol/l
0.38
169
1293
15
42
3.64
4.79
1.5
1.3
5243.75
30425.33
e6/l
—
8
24
188
1406
1.49
4.71
2.7
3.1
1712.06
1414.84
ng/l
0.32
151
1196
514
4698
1.71
4.70
42.4
14.0
35.65
24.94
mg/l
8.65
493
3715
15
43
3.55
4.64
1.5
1.3
3451.25
1920.86
e6/l
—
8
28
30
129
2.40
4.58
2.7
4.0
—
—
—
0
0
279
2266
1.44
4.50
6.0
4.8
0.00
0.00
estimate
-0.00
75
408
36
170
2.19
4.44
2.4
3.6
1.37
1.98
ratio
—
5
21
16
50
3.26
4.36
1.7
1.4
—
—
—
0
0
36
172
2.16
4.32
2.6
3.6
52.26
89.47
mg/l
0.48
30
139
36
172
2.16
4.32
2.5
3.6
31.52
31.68
mg/l
0.01
30
140
14
41
3.47
4.21
1.6
1.5
—
—
—
0
0
22
87
2.59
4.01
2.2
2.3
—
—
—
0
0
23
94
2.51
3.93
1.9
2.4
63.78
61.14
%
0.18
23
94
19
71
2.73
3.86
3.2
2.7
4.36
4.07
mmol/l
1.01
19
71
19
71
2.73
3.86
3.2
2.7
104.84
104.65
mmol/l
0.06
19
71
62
376
1.72
3.72
5.3
3.5
—
—
—
0
0
89
593
1.59
3.72
1.3
1.3
—
—
—
0
0
9
16
5.69
3.67
1.6
2.2
—
—
—
0
0
68
425
1.68
3.66
2.4
2.4
3.96
7.48
ug/l
3.23
54
374
14
40
3.56
3.63
2.1
1.2
—
—
—
0
0
72
459
1.65
3.60
7.0
4.4
—
—
—
0
0
55
326
1.76
3.58
1.2
1.2
—
—
—
0
0
7
9
7.85
3.56
1.1
1.2
—
—
—
0
0
14
46
3.09
3.55
4.7
2.7
—
—
—
0
0
185
1449
1.40
3.45
5.0
3.9
—
—
—
0
0
162
1240
1.42
3.45
1.6
1.3
—
—
—
0
0
13
37
3.57
3.42
1.7
1.2
—
—
—
0
0
163
1253
1.41
3.38
4.9
3.2
—
—
—
0
0
12
33
3.69
3.30
5.0
2.8
—
—
—
0
0
136
1767
0.70
3.26
3.3
2.9
—
—
—
0
0
223
1817
1.36
3.24
3.6
3.3
6.25
5.82
ph
—
10
147
18
72
2.55
3.24
2.1
1.6
31.17
32.81
pg
0.91
18
72
10
24
4.22
3.20
1.3
1.2
164.70
137.18
nmol/l
—
10
24
27
131
2.11
3.17
1.1
1.2
—
—
—
0
0
34
182
1.92
3.07
4.4
4.2
—
—
—
0
0
6
8
7.56
3.06
1.7
1.0
17.90
19.09
umol/l
—
6
8
7
12
5.89
3.03
2.3
4.1
3.08
1.20
ug/l
—
7
12
7
12
5.89
3.03
1.4
1.5
—
—
—
0
0
18
75
2.44
2.99
5.3
3.5
62.78
58.07
%
0.67
18
75
5
5
10.07
2.98
1.2
1.4
—
—
—
0
0
12
37
3.29
2.94
4.0
1.5
0.97
1.04
g/l
0.23
12
37
17
70
2.47
2.90
3.4
2.8
—
—
—
0
0
7
13
5.43
2.87
2.4
1.5
—
—
—
0
0
8
19
4.25
2.68
1.7
1.9
73.13
60.91
ug/l
—
8
19
6
11
5.50
2.55
1.2
1.0
—
—
—
0
0
6
11
5.50
2.55
1.8
1.5
—
—
—
0
0
11
37
3.01
2.50
1.1
1.1
—
—
—
0
0
153
1221
1.34
2.45
5.0
3.6
0.00
0.01
estimate
0.50
69
392
5
8
6.29
2.37
1.0
1.1
—
—
—
0
0
11
39
2.85
2.35
1.5
1.3
—
—
—
0
0
6
13
4.65
2.27
4.2
1.8
—
—
—
0
0
23
413
0.54
2.27
1.5
1.4
—
—
—
0
0
16
73
2.22
2.23
5.1
3.1
3.87
4.59
e9/l
0.72
16
73
5
9
5.59
2.21
1.0
1.2
—
—
—
0
0
520
4943
1.42
2.12
44.2
16.4
138.74
139.70
mmol/l
12.12
513
4813
46
304
1.56
2.05
3.2
3.1
4.53
7.89
e9/l
0.80
35
247
6
15
4.03
2.04
1.0
1.2
—
—
—
0
0
12
50
2.43
2.03
2.2
2.3
663.00
607.32
ml
—
7
28
12
51
2.38
1.96
2.4
1.5
—
—
—
0
0
520
4961
1.39
1.90
44.7
16.6
3.95
3.99
mmol/l
2.86
513
4826
95
1204
0.75
1.83
2.8
3.0
0.60
0.73
ug/l
1.73
60
773
5
12
4.19
1.82
2.2
1.6
—
—
—
0
0
8
29
2.78
1.79
2.1
1.9
9.13
9.82
mmol/l
—
8
29
8
29
2.78
1.79
4.3
2.1
—
—
—
0
0
36
233
1.58
1.78
2.9
2.3
—
—
—
0
0
16
81
2.00
1.76
2.2
2.8
1.02
0.82
nmol/l
—
5
64
9
36
2.52
1.74
2.3
1.2
1.58
1.12
promille
—
9
28
8
30
2.69
1.73
2.1
3.8
—
—
—
0
0
8
30
2.69
1.73
2.0
2.0
—
—
—
0
0
11
48
2.32
1.71
1.2
1.1
—
—
—
0
0
10
41
2.46
1.65
1.9
3.4
11.75
10.59
%
—
10
41
5
14
3.59
1.62
2.4
1.4
—
—
—
0
0
8
33
2.44
1.54
1.5
3.6
—
—
—
0
0
6
21
2.88
1.51
1.0
1.1
—
—
—
0
0
38
261
1.49
1.47
1.1
1.2
77.87
138.35
iu/ml
—
10
107
7
28
2.52
1.45
2.9
1.6
99.29
77.50
umol/l
—
7
28
7
29
2.43
1.39
1.0
1.1
—
—
—
0
0
7
29
2.43
1.39
2.1
2.7
1473.14
1226.31
u/ml
—
7
29
13
67
1.96
1.39
1.0
1.2
—
—
—
0
0
13
67
1.96
1.39
1.0
1.2
—
—
—
0
0
368
3417
1.20
1.39
4.5
3.8
—
—
—
0
0
9
41
2.21
1.37
1.0
1.1
—
—
—
0
0
5
17
2.96
1.36
1.0
1.0
—
—
—
0
0
11
54
2.06
1.33
1.1
1.1
—
—
—
0
0
30
203
1.50
1.27
1.9
3.0
—
—
—
0
0
123
1040
1.23
1.23
3.3
3.5
—
—
—
0
0
120
1013
1.23
1.22
1.7
1.7
511.77
24463438.93
pmol/l
0.92
95
838
13
71
1.85
1.20
1.9
2.6
—
—
—
0
0
0
33
0.00
1.16
0.0
1.0
—
222.73
—
0
15
5
20
2.51
1.15
8.8
7.3
—
—
—
0
0
17
269
0.62
1.13
1.5
1.5
—
—
—
0
0
8
40
2.01
1.12
1.1
1.1
—
—
—
0
0
15
89
1.70
1.08
3.7
3.8
—
—
—
0
0
453
4715
0.83
1.08
5.1
4.5
1.34
1.44
mmol/l
4.88
414
4342
21
137
1.55
1.07
5.7
4.8
—
—
—
0
0
10
52
1.94
1.06
1.0
1.2
—
—
—
0
0
7
33
2.13
1.06
5.6
2.2
—
—
—
0
0
59
466
1.30
1.06
1.6
1.5
—
—
—
0
0
9
48
1.89
1.01
2.0
2.6
—
—
—
0
0
11
62
1.79
0.94
1.6
1.3
—
—
—
0
0
6
27
2.23
0.93
1.2
1.4
5.10
6.38
ug/l
—
6
22
6
30
2.01
0.87
1.8
1.3
126.50
695.84
u/l
—
6
25
459
4745
0.86
0.84
5.2
4.6
4.44
4.64
mmol/l
3.48
422
4391
8
141
0.56
0.83
1.0
1.1
—
—
—
0
0
21
146
1.45
0.83
1.3
1.2
—
2.14
—
0
9
187
2045
0.88
0.79
4.3
4.8
2.30
2.69
ug/l
0.28
159
1839
21
148
1.43
0.79
1.8
1.7
—
—
—
0
0
520
5072
1.21
0.77
28.5
10.3
35.72
27.02
u/l
10.72
511
4901
13
197
0.65
0.76
1.1
1.1
—
—
—
0
0
6
34
1.77
0.76
1.0
1.6
—
—
—
0
0
32
247
1.31
0.72
1.2
1.3
468.38
285.75
u/ml
0.24
32
225
5
26
1.93
0.70
1.2
1.2
—
—
—
0
0
17
118
1.45
0.70
2.1
1.6
12722.11
12258.27
e6/l
—
9
86
5
28
1.79
0.66
1.6
1.3
—
—
—
0
0
505
4931
1.16
0.63
38.5
13.2
—
—
—
0
0
10
152
0.65
0.62
1.0
1.1
—
—
—
0
0
13
88
1.49
0.61
1.7
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
111
996
1.14
0.59
4.3
3.6
1.02
1.02
kg/l
0.20
18
151
8
53
1.52
0.58
1.1
1.3
—
—
nmol/l
—
0
0
15
106
1.43
0.58
2.1
1.4
—
—
—
0
0
12
81
1.49
0.57
1.8
1.5
—
—
—
0
0
39
471
0.82
0.57
1.5
1.5
—
—
—
0
0
11
73
1.52
0.56
1.3
1.4
—
—
—
0
0
27
213
1.28
0.55
1.7
1.6
—
—
—
0
0
7
46
1.53
0.48
1.3
1.8
—
—
—
0
0
30
246
1.23
0.46
6.3
3.9
—
—
—
0
0
15
112
1.35
0.45
2.1
1.4
—
—
—
0
0
7
51
1.38
0.44
15.4
9.1
9.56
6.82
mmol/l
—
7
43
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
15
114
1.32
0.41
2.1
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
25.64
—
0
11
10
71
1.42
0.39
1.7
1.6
19.70
18.01
ug/l
—
10
71
15
115
1.31
0.39
2.1
1.4
—
—
—
0
0
123
1323
0.91
0.39
1.8
1.7
1.58
1.42
mmol/l
0.84
102
1107
447
4564
0.92
0.39
4.9
4.1
1.44
1.31
mmol/l
1.85
406
4179
456
4466
1.09
0.38
7.7
5.9
43.66
40.19
mmol/mol
4.11
423
4148
23
189
1.23
0.36
1.7
1.9
—
—
—
0
0
18
144
1.26
0.35
2.9
2.3
23.82
81.85
ug/min
1.94
11
83
460
4683
0.92
0.34
5.2
4.6
6.33
6.01
mmol/l
3.90
414
4263
476
4839
0.92
0.34
5.5
5.1
2.58
2.76
mmol/l
4.16
432
4457
10
74
1.36
0.32
1.4
1.7
—
—
—
0
0
40
353
1.14
0.31
1.2
1.3
—
—
—
0
0
40
353
1.14
0.31
1.8
1.4
—
—
—
0
0
10
75
1.34
0.30
1.2
1.4
—
—
—
0
0
7
56
1.25
0.29
1.3
1.2
—
—
—
0
0
8
62
1.29
0.28
1.1
1.3
0.84
0.58
nmol/l
—
8
56
353
3450
1.06
0.26
4.0
3.7
14.81
14.87
pmol/l
0.14
315
3097
10
127
0.78
0.25
1.1
1.6
—
—
—
0
0
14
114
1.23
0.25
2.2
1.4
—
—
—
0
0
9
77
1.17
0.24
3.7
2.8
—
—
—
0
0
43
389
1.11
0.24
3.6
3.1
—
—
—
0
0
14
115
1.22
0.23
1.3
1.6
413.00
265.06
mu/l
0.83
14
109
5
42
1.19
0.21
1.4
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
18.52
—
0
12
0
13
0.00
0.21
0.0
1.1
—
0.73
—
0
8
16
187
0.85
0.20
3.1
1.7
—
—
—
0
0
523
5274
0.93
0.20
59.9
20.8
126.91
136.63
g/l
27.25
517
5187
523
5272
0.93
0.19
59.4
20.6
4.29
4.52
e12/l
13.37
507
5120
523
5271
0.93
0.18
59.4
20.7
7.62
6.71
e9/l
1.24
509
5117
523
5271
0.93
0.18
59.1
20.6
30.15
30.40
pg
1.78
518
5188
7
59
1.19
0.18
1.1
1.3
—
—
—
0
0
523
5270
0.94
0.18
59.2
20.6
91.13
91.17
fl
0.06
518
5187
523
5270
0.94
0.18
59.4
20.7
235.82
246.71
e9/l
1.48
511
5129
11
91
1.21
0.17
1.2
1.8
—
—
—
0
0
23
205
1.13
0.17
1.0
1.1
—
132.20
—
0
5
8
69
1.16
0.16
1.3
1.2
—
—
—
0
0
6
77
0.78
0.15
1.2
1.1
—
13.22
—
0
5
33
303
1.09
0.15
3.3
2.7
—
—
—
0
0
9
78
1.16
0.15
1.9
1.3
—
—
—
0
0
523
5266
0.94
0.15
60.0
20.9
38.08
40.30
%
11.11
493
4911
20
182
1.10
0.11
1.3
1.3
—
—
—
0
0
11
125
0.88
0.10
1.1
1.2
—
—
—
0
0
14
155
0.90
0.09
15.3
10.1
—
—
—
0
0
6
54
1.11
0.09
1.0
2.1
—
—
—
0
0
5
62
0.80
0.08
4.2
2.5
—
—
—
0
0
428
4250
1.03
0.08
4.8
4.4
2.07
2.23
mu/l
0.23
387
3847
16
147
1.09
0.07
1.6
1.8
43.69
40.04
nmol/l
0.21
16
142
10
111
0.90
0.06
2.3
2.5
—
—
—
0
0
28
294
0.95
0.06
1.1
1.3
—
57.71
—
0
22
71
727
0.97
0.05
1.2
1.3
10.22
12.38
u/ml
0.11
20
287
12
110
1.09
0.05
1.8
1.9
152.67
231.36
pmol/l
2.63
12
101
74
749
0.99
0.01
1.3
1.3
26.28
36.49
iu/ml
0.46
20
244
10
104
0.96
0.00
1.1
1.3
—
—
—
0
0
28
277
1.01
0.00
1.2
1.3
—
—
—
0
0
42
422
0.99
0.00
2.2
2.2
11.72
13.64
nmol/l
0.77
37
384
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
17.45
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
65
0.92
-0.00
1.0
1.2
75.88
51.41
mu/l
—
6
57
0
6
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
40.00
—
0
6
0
9
0.00
-0.00
0.0
1.2
—
1.81
—
0
9
0
7
0.00
-0.00
0.0
1.0
—
7.22
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint I9_PVT and mortality.

Females

Parameter HR [95% CI] p-value
I9_PVT 2.849 [2.24, 3.63] < 0.001
Birth year 0.997 [0.99, 1.01] 0.487

During the follow-up period (1.1.1998 — 31.12.2019), 395 out of 988 females with I9_PVT died.

Males

Parameter HR [95% CI] p-value
I9_PVT 4.077 [3.25, 5.12] < 0.001
Birth year 0.987 [0.98, 1.0] 0.021

During the follow-up period (1.1.1998 — 31.12.2019), 649 out of 1429 males with I9_PVT died.

Mortality risk

Mortality risk for people of age

years, who have I9_PVT.

N-year risk Females Males
1 0.295% 0.843%
5 1.882% 4.944%
10 4.634% 12.337%
15 8.574% 21.809%
20 14.689% 34.055%

Relationships between endpoints

Index endpoint: I9_PVT – Portal vein thrombosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data