No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
531 |
4. Check minimum number of eventsNone |
531 |
5. Include endpointsNone |
531 |
6. Filter based on genotype QC (FinnGen only) |
531 |
Control definitions (FinnGen only)
- Control exclude
- I9_DISVEINLYMPH
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I80-I89
- Name in latin
- Thrombosis venae portae
Similar endpoints
↥List of similar endpoints to
Portal vein thrombosis
based on the number of shared cases.
Similar with more cases:
- Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)
- Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3823 | 1578 | 2210 |
| Only index persons | 3061 | 1272 | 1789 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.06 |
| Only index persons | 0.06 | 0.05 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 62.20 | 62.36 | 62.10 |
| Only index persons | 61.19 | 60.50 | 61.68 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 531 | 226 | 305 |
| Unadjusted period prevalence (%) | 0.11 | 0.08 | 0.13 |
| Median age at first event (years) | 61.88 | 60.07 | 63.22 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 459
- Matched controls
- 4588
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I81
ICD-10 Finland
Portal vein thrombosis
+∞
323.0
440
*
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
+∞
96.3
89
*
B01AB05
ATC
enoxaparin; parenteral
7.3
83.6
282
818
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.7
64.2
261
862
JN3BD
NOMESCO Finland
Extensive abdominal CT
8.1
59.6
151
262
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.3
58.7
163
323
B01AA03
ATC
warfarin; systemic
5.6
54.3
199
554
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
8.9
52.9
123
182
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
470.1
44.0
43
*
I85.0
ICD-10 Finland
Oesophageal varices with bleeding
+∞
38.0
36
*
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
141.7
37.3
39
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
42.4
37.3
46
12
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
22.5
37.1
54
27
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
25.4
35.7
50
22
B01AB10
ATC
tinzaparin; parenteral
7.9
34.3
83
125
R18
ICD-10 Finland
Ascites
18.8
33.7
52
31
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.5
32.7
219
959
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
334.6
31.2
31
*
JN3AD
NOMESCO Finland
Abdominal CT examination
6.0
30.5
90
178
C03DA01
ATC
spironolactone; oral
4.9
29.0
104
257
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.3
29.0
73
116
Z51.5
ICD-10 Finland
Palliative care
6.9
26.2
68
112
C03CA01
ATC
furosemide; systemic
3.1
26.2
195
884
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
26.0
263
1453
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.5
25.5
100
268
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
5.3
24.9
81
178
K92.1
ICD-10 Finland
Melaena
6.4
24.8
68
121
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
91.7
23.9
26
*
PHD99
NOMESCO Finland
Resection of other vein
252.6
23.9
24
*
N02AA05
ATC
oxycodone; systemic
3.8
23.6
112
356
JN4BD
NOMESCO Finland
Extensive body CT
4.4
23.5
94
256
TPH04
NOMESCO Finland
Cathetrisation of vein
3.2
23.3
150
603
45499
ICD-8 Finland
Varicose veins of lower extremities, Other and unspecified, without ulcer
+∞
23.1
22
*
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
20.3
22.9
34
18
130
Kela drug reimbursment
Malignant tumour
4.8
22.9
82
199
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
13.2
22.3
39
32
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
22.0
118
413
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
40.9
22.0
27
7
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
18.6
21.7
33
19
K83.0
ICD-10 Finland
Cholangitis
20.1
21.6
32
17
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.1
21.1
53
83
JAH00
NOMESCO Finland
Laparotomy
9.2
20.9
44
52
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
8.5
20.8
46
59
N02AX02
ATC
tramadol; systemic, rectal
2.6
20.8
236
1330
A06AD11
ATC
lactulose; oral
3.4
20.8
113
398
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
27.0
20.7
28
11
B01AB04
ATC
dalteparin; parenteral
6.5
20.3
54
92
R50.9
ICD-10 Finland
Fever, unspecified
3.5
20.1
104
351
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
11.7
20.1
37
34
A03FA01
ATC
metoclopramide; systemic, rectal
3.1
19.7
127
504
UJF32
NOMESCO Finland
Coloscopy
2.8
19.6
157
715
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
13.1
18.9
33
27
A02BC02
ATC
pantoprazole; systemic
2.5
18.7
323
2230
K86.1
ICD-10 Finland
Other chronic pancreatitis
31.5
18.5
24
8
C07AA05
ATC
propranolol; systemic
3.1
18.5
117
456
A09AA02
ATC
multienzymes (lipase, protease etc.)
14.5
18.0
30
22
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.2
17.8
106
394
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.8
17.7
51
96
Z94.4
ICD-10 Finland
Liver transplant status
186.9
17.6
18
*
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
12.7
17.6
31
26
K92.0
ICD-10 Finland
Haematemesis
9.4
17.5
36
41
XF400
NOMESCO Finland
ECG with 12 standard connections
3.0
17.5
116
465
J01MA12
ATC
levofloxacin; systemic
2.9
17.3
121
502
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
14.8
17.0
28
20
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
18.8
16.6
25
14
K94
ICPC
Phlebitis/thrombophlebitis
41.7
16.5
20
5
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
31.3
16.2
21
7
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
7.1
15.9
39
59
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
10.3
15.9
31
32
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
18.0
15.8
24
14
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
18.0
15.8
24
14
45299
ICD-8 Finland
Portal vein thrombosis
+∞
15.7
15
*
D45
ICD-10 Finland
Polycythaemia vera
20.1
15.7
23
12
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
8.6
15.3
33
41
A05AA02
ATC
ursodeoxycholic acid; oral
18.6
15.3
23
13
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
46.7
15.2
18
*
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
26.0
14.8
20
8
K83.1
ICD-10 Finland
Obstruction of bile duct
12.5
14.8
26
22
WX002
NOMESCO Finland
Sedation and analgesia
2.7
14.6
116
512
PC2DE
NOMESCO Finland
Ultrasound examination of liver vasculature with Doppler method
154.7
14.5
15
*
JJC00
NOMESCO Finland
Allogenic transplantation of liver
154.7
14.5
15
*
UJK02
NOMESCO Finland
ERCP
9.6
14.4
29
32
J01MA02
ATC
ciprofloxacin; systemic
2.2
14.2
208
1251
C07AG02
ATC
carvedilol; oral
4.6
14.2
50
118
UJF30
NOMESCO Finland
Ileoscopy through colon
3.5
14.2
69
219
WW500
NOMESCO Finland
Blood transfusion
5.9
14.0
39
71
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
8.4
13.8
30
38
WX408
NOMESCO Finland
General anesthesy, balanced
2.3
13.7
153
810
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
13.6
77
273
JN4AD
NOMESCO Finland
Body CT examination
3.9
13.6
58
165
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
18.9
13.5
20
11
ZX120
NOMESCO Finland
Intravenous
3.4
13.4
68
223
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
13.2
98
414
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
6.5
13.1
34
56
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.9
12.9
29
39
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
14.6
12.9
21
15
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.7
12.8
57
168
D64.9
ICD-10 Finland
Anaemia, unspecified
3.3
12.8
68
231
A10AE04
ATC
insulin glargine; parenteral
3.3
12.7
66
220
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
6.1
12.7
34
59
A04AA02
ATC
granisetron; systemic, transdermal
4.5
12.6
45
108
4549X
ICD-9 Finland
Varicose veins of lower extremities, Without mention of ulcer or inflammation
+∞
12.6
12
*
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
+∞
12.6
12
*
D68.8
ICD-10 Finland
Other specified coagulation defects
20.7
12.5
18
9
R4110
NOMESCO Finland
Physiotherapy
2.3
12.5
142
749
PHD76
NOMESCO Finland
Resection of long saphenous vein
133.5
12.5
13
*
K76.6
ICD-10 Finland
Portal hypertension
133.5
12.5
13
*
127
Kela drug reimbursment
Transplant complication
12.1
12.4
22
19
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
12.1
12.4
22
19
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
10.9
12.4
23
22
L01BC06
ATC
capecitabine; oral
5.9
12.3
34
61
UJD02
NOMESCO Finland
Gastroscopy
4.4
12.2
44
107
K76.9
ICD-10 Finland
Liver disease, unspecified
9.7
12.1
24
26
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.9
12.0
39
85
K86.3
ICD-10 Finland
Pseudocyst of pancreas
48.0
11.9
14
*
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
6.1
11.9
32
56
I86.4
ICD-10 Finland
Gastric varices
+∞
11.5
11
*
K72.1
ICD-10 Finland
Chronic hepatic failure
+∞
11.5
11
*
4520A
ICD-9 Finland
Portal vein thrombosis[THROMBOSIS VENAE PORTAE]
+∞
11.5
11
*
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
4.6
11.4
39
90
K85
ICD-10 Finland
Acute pancreatitis
10.0
11.4
22
23
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
11.3
59
198
8170/3-C22.0
ICD-O-3
Hepatocellular carcinoma, NOS, of liver
20.7
11.2
16
8
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
6.0
11.1
30
53
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
14.4
11.1
18
13
H02AB02
ATC
dexamethasone; systemic
3.1
10.9
61
213
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
8.6
10.9
23
28
A02BC05
ATC
esomeprazole; systemic
2.0
10.8
194
1232
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
22.1
10.7
15
7
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
22.1
10.7
15
7
JCA20
NOMESCO Finland
Ligature of oesophageal varices
+∞
10.5
10
*
L01XX05
ATC
hydroxycarbamide; oral
12.4
10.4
18
15
JN4CD
NOMESCO Finland
Very extensive body CT
4.3
10.4
38
94
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
8.7
10.2
21
25
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.3
10.1
37
92
P01AB01
ATC
metronidazole; oral, rectal
2.0
10.0
177
1109
WX892
NOMESCO Finland
Monitored bed care
3.1
9.9
55
191
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
11.0
9.9
18
17
R4190
NOMESCO Finland
Nutritional therapy
5.6
9.8
28
53
WZC30
NOMESCO Finland
Teaching
2.7
9.8
71
295
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
9.7
49
160
K85.1
ICD-10 Finland
Biliary acute pancreatitis
56.2
9.7
11
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
9.7
84
385
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.3
9.7
49
161
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
11.7
9.6
17
15
A41.9
ICD-10 Finland
Sepsis, unspecified
4.7
9.5
31
69
A02BC01
ATC
omeprazole; systemic
2.0
9.5
139
806
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
102.1
9.4
10
*
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
102.1
9.4
10
*
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
30.7
9.4
12
*
TPH00
NOMESCO Finland
Phlebotomy
30.7
9.4
12
*
WX882
NOMESCO Finland
High dependency care
5.5
9.4
27
52
TK800
NOMESCO Finland
Hemodialysis
9.0
9.4
19
22
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
11.0
9.4
17
16
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
14.0
9.2
15
11
L04AA06
ATC
mycophenolic acid; systemic
8.6
9.2
19
23
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
9.0
123
691
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
8.9
129
741
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
8.9
68
288
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
12.9
8.9
15
12
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
8.9
8.9
18
21
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
5.8
8.9
24
43
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
8.8
150
919
A07AA11
ATC
rifaximin; oral
51.0
8.7
10
*
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
6.2
8.6
22
37
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
28.1
8.5
11
*
J81
ICD-10 Finland
Pulmonary oedema
28.1
8.5
11
*
K76.89
ICD-10 Finland
Other specified diseases of liver
91.7
8.4
9
*
5611
FHL
Vena saphena Magna and / or swarm of nodule and possible local emissions
91.7
8.4
9
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
13.1
8.4
14
11
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
+∞
8.4
8
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.6
8.3
60
248
XW000
NOMESCO Finland
Bone marrow biopsy
3.9
8.3
33
89
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.2
8.2
30
75
A04AA01
ATC
ondansetron; systemic, rectal
3.3
8.2
40
128
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.1
8.2
46
161
R60.0
ICD-10 Finland
Localized oedema
2.8
8.2
54
210
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
8.1
59
245
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.4
8.1
23
44
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
34.0
8.1
10
*
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
34.0
8.1
10
*
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
4.4
8.0
28
67
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
8.0
100
538
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.7
8.0
26
58
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
7.8
87
445
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
4.3
7.8
28
69
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.1
7.8
29
74
UJF92
NOMESCO Finland
Capsular endoscopy
6.6
7.8
19
30
JMA10
NOMESCO Finland
Transabdominal total splenectomy
15.4
7.8
12
8
JFB00
NOMESCO Finland
Partial resection of small intestine
7.6
7.7
17
23
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
7.6
7.7
17
23
K65.0
ICD-10 Finland
Acute peritonitis
12.1
7.6
13
11
K29.6
ICD-10 Finland
Other gastritis
10.3
7.6
14
14
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
7.6
91
481
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
5.2
7.5
22
44
RD210
NOMESCO Finland
NA
7.9
7.4
16
21
L03AB05
ATC
interferon alfa-2b; parenteral
81.4
7.4
8
*
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.8
7.4
47
180
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
8.6
7.4
15
18
A46
ICD-10 Finland
Erysipelas
2.3
7.3
73
354
J01DB01
ATC
cefalexin; oral
1.8
7.3
353
2963
K81.0
ICD-10 Finland
Acute cholecystitis
5.0
7.2
22
46
D01
ICPC
Abdominal pain/cramps general
2.7
7.2
47
184
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
20.4
7.2
10
5
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
12.3
7.1
12
10
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.0
7.1
40
142
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.7
7.0
29
82
JAH01
NOMESCO Finland
Laparoscopy
4.0
6.9
26
68
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
9.5
6.8
13
14
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
40.7
6.8
8
*
K99
ICPC
Cardiovascular disease other
5.1
6.7
20
41
SPAT1262
SPAT
Handing over of treatment supplies
2.0
6.6
92
515
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.8
6.6
26
71
N02BE01
ATC
paracetamol; systemic, rectal
1.8
6.6
372
3211
A41.8
ICD-10 Finland
Other specified sepsis
7.0
6.6
15
22
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
6.5
139
904
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.6
6.5
46
190
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
7.6
6.5
14
19
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.3
6.4
30
94
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.3
6.4
31
100
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
11.2
6.3
11
10
K56.7
ICD-10 Finland
Ileus, unspecified
11.2
6.3
11
10
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.0
6.3
23
59
XX4BW
NOMESCO Finland
NA
+∞
6.3
6
*
JJ5AT
NOMESCO Finland
NA
+∞
6.3
6
*
1324
FHL
Esophagoscopy and sclerotherapy
+∞
6.3
6
*
I82.21
ICD-10 Finland
Emboli and thrombosis in the inferior vena cava
+∞
6.3
6
*
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
27.1
6.2
8
*
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
27.1
6.2
8
*
AA1AD
NOMESCO Finland
CT of head and brain
1.8
6.2
110
672
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
6.1
136
890
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.2
6.1
30
98
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.3
6.0
53
242
Mortality – FinRegistry
↥Association
Association between endpoint I9_PVT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_PVT | 2.849 [2.24, 3.63] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.487 |
During the follow-up period (1.1.1998 — 31.12.2019), 395 out of 988 females with I9_PVT died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_PVT | 4.077 [3.25, 5.12] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 649 out of 1429 males with I9_PVT died.
Mortality risk
Mortality risk for people of age
years, who have I9_PVT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.295% | 0.843% |
| 5 | 1.882% | 4.944% |
| 10 | 4.634% | 12.337% |
| 15 | 8.574% | 21.809% |
| 20 | 14.689% | 34.055% |
Relationships between endpoints
↥Index endpoint: I9_PVT – Portal vein thrombosis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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