Disorders related to long gestation and high birth weight

P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P08 Cause of death: ICD-10 — P08 2 out of 7 registries used, show all original rules.	92
4. Check minimum number of events None	92
5. Include endpoints None	92
6. Filter based on genotype QC (FinnGen only)	92

Control definitions (FinnGen only)

Control exclude: P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P0[5-8]
Name in latin: Perturbationes ad gestationem longum et pondus partuale grave pertinentes

NAME	P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT
CONTROL_EXCLUDE	P16_DISORD_RELATED_LENGTH_GESTATION_FETAL_GROWTH
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P08
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P08
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorders related to long gestation and high birth weight based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	6743	2756	3986
Only index persons	2770	1116	1654
Unadjusted period prevalence (%)
Whole population	0.10	0.08	0.11
Only index persons	0.05	0.04	0.06
Median age at first event (years)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	92	54	38
Unadjusted period prevalence (%)	0.02	0.02	0.02
Median age at first event (years)	0.00	0.00	0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
80: Matched controls
799

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

P08.0

ICD-10 Finland

Exceptionally large baby

+∞

43.8

P08.1

ICD-10 Finland

Other heavy for gestational age infants

+∞

41.3

P07.3

ICD-10 Finland

Other preterm infants

+∞

19.6

P70.4

ICD-10 Finland

Other neonatal hypoglycaemia

34.9

16.6

P70.1

ICD-10 Finland

Syndrome of infant of a diabetic mother

70.8

15.5

P08.2

ICD-10 Finland

Post-term infant, not heavy for gestational age

+∞

12.8

Z87.6

ICD-10 Finland

Personal history of certain conditions arising in the perinatal period

15.0

9.9

P22.1

ICD-10 Finland

Transient tachypnoea of newborn

10.4

6.0

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

0.00

3.14

0.0

10.5

—

1071.4

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

3.70

1.87

6.5

5.8

2.2

7.0

u/ml

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

117

0.39

1.37

2.8

2.0

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

118

0.39

1.37

13.6

7.8

0.9

2.9

mg/l

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.44

1.15

2.3

2.4

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.99

0.0

1.2

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.99

0.0

1.8

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

130

0.50

0.97

1.4

2.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

1.88

0.92

1.5

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

150

0.56

0.88

1.6

2.1

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

1.81

0.85

2.5

1.8

455.0

320.8

mu/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

206

0.62

0.84

2.7

3.2

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

1.87

0.80

1.8

1.6

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.87

0.80

1.0

1.3

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

0.80

0.0

1.2

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

0.00

0.79

0.0

2.7

—

91.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

776

0.67

0.76

4.0

3.9

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

393

0.72

0.76

2.8

2.0

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.81

0.73

2.6

2.1

—

(3044640) Blood type and Crossmatch panel - Blood

188

0.64

0.72

5.5

4.3

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.97

0.72

1.0

1.2

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

1.97

0.72

1.0

160.6

168.2

g/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

369

0.72

0.71

3.5

7.2

112.9

113.6

ml/min/173m2

0.06

246

(3003458) Phosphate [Moles/volume] in Serum or Plasma

185

0.65

0.67

11.5

12.9

1.4

mmol/l

0.27

180

(3015736) pH of Urine

258

0.71

0.62

2.5

3.5

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

0.61

0.0

2.1

—

(3008295) Osmolality of Serum or Plasma

0.00

0.61

0.0

1.2

—

296.9

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.61

0.0

6.7

—

61.6

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

0.61

0.0

2.8

—

1.7

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.61

0.0

3.9

—

16.9

—

(40766183) Gliadin peptide IgA Ab [Units/volume] in Serum by Immunoassay

0.00

0.61

0.0

1.1

—

0.4

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.61

0.0

1.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

158

0.65

0.59

5.4

3.9

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.66

0.57

1.0

1.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

211

0.71

0.56

1.9

3.7

—

(3006315) Basophils [#/volume] in Blood

448

0.78

0.53

12.9

10.9

0.0

e9/l

0.26

361

(3022313) Gas panel - Capillary blood

183

1.34

0.51

10.3

11.5

—

(3035350) Ketones [Presence] in Urine by Test strip

334

0.77

0.50

2.4

3.7

0.0

estimate

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

250

0.74

0.50

5.5

5.2

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

117

0.65

0.49

1.6

1.7

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.58

0.48

13.8

13.7

97.0

90.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

484

0.79

0.48

16.1

12.8

3.5

e9/l

0.05

397

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

1.46

0.47

1.4

1.3

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

215

0.74

0.46

2.6

2.7

—

(3027945) Reticulocytes/100 erythrocytes in Blood

114

1.38

0.44

5.6

8.3

1.4

0.00

109

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

599

0.80

0.44

3.4

3.6

2.0

2.1

mu/l

0.25

564

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

1.65

0.44

2.4

2.1

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

1.65

0.44

2.4

2.2

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

192

0.74

0.43

16.5

10.7

5.5

5.7

kpa

0.48

187

(3009508) Creatinine [Moles/volume] in Urine

170

0.73

0.43

2.2

4.9

7.5

8.2

mmol/l

0.18

163

(3027653) Mycophenolate [Mass/volume] in Serum or Plasma

0.00

0.41

0.0

7.1

—

2.1

—

(40761873) Peanut recombinant (rAra h) 1 IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

0.7

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.41

0.0

1.1

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.41

0.0

1.1

—

(4062490)

0.00

0.41

0.0

1.2

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.41

0.0

1.4

—

(3001604) Monocytes [#/volume] in Blood

449

0.81

0.41

12.6

10.9

0.6

e9/l

0.25

361

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.41

0.0

2.2

—

(3016845) Adenovirus Ag [Presence] in Specimen by Immunofluorescence

0.00

0.41

0.0

1.2

—

(3020891) Body temperature

0.00

0.41

0.0

7.3

—

(3044889) 12 lead EKG panel

264

0.78

0.40

2.0

2.1

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.45

0.40

4.2

2.5

4.9

5.2

pmol/l

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.45

0.40

1.0

1.2

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.41

0.39

1.6

1.7

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

1.41

0.39

2.4

2.1

—

(3009261) Glucose [Presence] in Urine by Test strip

334

0.81

0.37

2.4

3.8

0.0

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

333

0.81

0.36

3.5

5.3

0.0

estimate

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

1.33

0.34

3.7

4.5

17.5

22.7

nmol/l

—

(3018010) Neutrophils/100 leukocytes in Blood

452

0.83

0.33

12.4

10.6

48.8

48.0

0.13

437

(3002030) Lymphocytes/100 leukocytes in Blood

461

0.84

0.32

12.3

10.8

36.5

36.7

0.04

446

(3021706) Oxygen [Partial pressure] in Arterial cord blood

1.35

0.31

1.0

2.4

3.2

kpa

—

(40761536) Microorganisms panel - Urine sediment

1.32

0.31

1.7

4.2

—

(3022096) Basophils/100 leukocytes in Blood

430

0.84

0.31

12.9

11.3

0.6

0.03

416

(3006598) pH of Arterial cord blood

1.29

0.31

1.0

—

(3041008) Bicarbonate [Moles/volume] standard in Arterial cord blood

1.29

0.31

1.0

17.9

19.4

mmol/l

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.29

0.31

1.6

1.4

—

(3003932) Carbon dioxide [Partial pressure] in Arterial cord blood

1.29

0.31

1.0

8.6

7.6

kpa

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

120

0.72

0.29

1.8

4.0

68.1

67.2

u/l

—

108

(40761511) CBC panel - Blood by Automated count

708

1.23

0.28

7.1

9.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

248

1.19

0.26

2.2

1.9

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.30

0.25

6.4

11.4

5.5

6.1

umol/l

0.15

(3003694) ABO and Rh group [Type] in Blood

231

0.83

0.25

1.8

1.7

—

(42870560) Thyrotropin [Units/volume] in Cord blood

1.20

0.25

1.0

11.4

8.9

mu/l

—

(3042936) Bacteria identified in Isolate by Culture

0.70

0.25

1.8

1.9

—

(3037522) Nuclear Ab [Titer] in Serum

0.70

0.25

1.2

1.7

—

540.0

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

1.37

0.24

1.4

1.5

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

1.37

0.24

1.8

1.6

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

1.37

0.24

1.4

1.5

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.26

0.23

2.6

2.4

—

(40758558) Short blood count panel - Blood

269

0.85

0.22

18.0

11.4

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3016031) Almond IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.4

—

2.1

—

(3024471) HLA-A [Type]

0.00

0.21

0.0

1.0

—

(3024932) HLA-DR beta [Type]

0.00

0.21

0.0

1.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3000504) BK virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.21

0.0

12.4

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

7.0

—

8.6

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

3.0

—

(40768446) Kidney Pathology biopsy report

0.00

0.21

0.0

3.0

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

44.6

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.21

0.0

1.0

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.21

0.0

1.0

—

(3014373) Corynebacterium diphtheriae Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

707.4

—

(3013924) Clostridium tetani IgG Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(42870588) Differential panel, method unspecified - Blood

340

0.87

0.21

17.1

11.4

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3018405) Lactate [Moles/volume] in Arterial blood

0.00

0.21

0.0

2.3

—

1.4

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

71.8

—

(3042733) HLA Ab [Presence] in Serum

0.00

0.21

0.0

2.3

—

(4268621)

0.00

0.21

0.0

2.3

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

10.7

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.21

0.0

1.2

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(36304419) Bacteria [Presence] in Urine

233

1.16

0.20

4.8

5.2

—

(3019198) Lymphocytes [#/volume] in Blood

460

0.88

0.20

11.9

10.8

2.3

2.4

e9/l

0.37

386

(3016921) Smith extractable nuclear Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(40761871) Peanut recombinant (rAra h) 3 IgE Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

2.5

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(44813793)

0.00

0.20

0.0

1.0

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.20

0.0

1.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.20

0.18

1.4

1.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

152

0.83

0.18

2.1

3.6

—

(3000991) Gas panel - Venous blood

183

0.85

0.18

15.2

13.4

—

(3026008) Bacteria identified in Urine by Culture

183

0.85

0.18

1.9

2.6

—

(3029937) Albumin [Presence] in Urine by Test strip

162

0.84

0.18

2.0

4.1

0.0

estimate

—

(3009542) Hematocrit [Volume Fraction] of Blood

748

1.18

0.17

16.3

17.1

39.5

38.5

0.90

681

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

394

1.12

0.17

2.1

2.2

5.2

5.3

mmol/l

0.33

357

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

209

1.13

0.15

13.0

11.6

1.4

1.0

mmol/l

0.29

151

(40760892) CBC W Ordered Manual Differential panel - Blood

149

0.85

0.15

3.8

6.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

200

0.88

0.14

2.2

2.5

—

(3009343) pH of Capillary blood

210

1.13

0.14

14.0

11.7

—

7.4

—

(3013115) Eosinophils [#/volume] in Blood

462

0.91

0.13

13.6

11.9

0.2

e9/l

0.00

386

(3020961) Endomysium IgA Ab [Titer] in Serum

115

0.85

0.11

1.0

1.5

—

55.8

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

217

0.90

0.10

1.6

2.2

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.17

0.10

1.0

—

(3000492) Spirometry study

1.14

0.10

1.4

1.3

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

1.12

0.10

1.8

2.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

107

1.14

0.09

1.8

2.0

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

264

1.09

0.09

4.7

5.5

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.06

0.09

1.3

1.2

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

215

1.09

0.08

18.8

16.3

24.3

24.4

mmol/l

0.07

215

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.82

0.08

1.5

1.2

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.82

0.08

1.0

1.4

—

(1761868) Lipid panel - Serum or Plasma

108

1.13

0.07

1.7

2.2

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

0.85

0.07

3.4

5.4

0.2

g/l

—

(3010813) Leukocytes [#/volume] in Blood

834

0.95

0.07

17.3

18.2

6.9

7.0

e9/l

0.20

780

(3026361) Erythrocytes [#/volume] in Blood

833

0.96

0.07

17.2

18.2

4.6

e12/l

0.26

782

(3007461) Platelets [#/volume] in Blood

832

0.98

0.07

17.3

18.3

277.6

274.5

e9/l

0.14

783

(3016879) Cocaine [Presence] in Urine

0.84

0.07

1.1

2.1

—

(3028300) Cannabinoids [Presence] in Urine

101

0.88

0.06

1.1

2.0

—

(3000764) Benzodiazepines [Presence] in Urine

100

0.89

0.06

1.1

2.1

—

(3027008) Opiates [Presence] in Urine

100

0.89

0.06

1.1

2.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

100

1.11

0.05

3.0

2.1

—

(3023368) Bacteria identified in Blood by Culture

120

1.10

0.05

5.6

5.0

—

(3019832) Treponema pallidum Ab [Presence] in Serum

130

1.09

0.05

1.4

1.8

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

740

0.93

0.04

10.5

12.8

18.6

24.0

mg/l

1.12

502

(36660697) Celiac disease serology panel - Serum

159

0.93

0.03

1.3

1.2

—

(3021589) Normoblasts [#/volume] in Blood

430

0.96

0.03

15.0

12.8

0.0

e9/l

0.45

317

(3048689) Calprotectin [Mass/mass] in Stool

179

0.94

0.03

2.3

3.1

61.5

68.4

ug/g

—

143

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

118

0.92

0.03

1.0

1.1

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

532

1.04

0.02

2.9

3.2

13.7

14.4

pmol/l

1.48

485

(40768804) Tissue Pathology biopsy report

137

0.94

0.01

1.5

1.7

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

163

1.05

0.01

1.5

1.8

—

(3007164) IgA [Mass/volume] in Serum or Plasma

329

1.00

0.00

1.2

1.8

1.6

1.4

g/l

0.35

160

(3037467) Urinalysis macro (dipstick) panel - Urine

457

1.01

0.00

3.7

4.6

—

(3041082) Glomerular basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.2

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

3.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.0

—

(3010464) Parainfluenza virus 1 Ag [Presence] in Specimen

0.00

0.0

1.5

—

(4211845)

0.00

0.0

1.4

—

(3028772) Osteocalcin [Mass/volume] in Serum or Plasma

0.00

0.0

2.4

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.1

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

0.0

3.4

—

46.6

—

(3019083) Insulin-like growth factor [Moles/volume] in Serum or Plasma

0.00

0.0

2.3

—

(3007302) Hemoglobin [Mass/volume] in Mixed venous blood

0.00

0.0

2.5

—

(40768441) Liver Pathology biopsy report

0.00

0.0

2.8

—

(1001833) Epstein Barr virus DNA [Units/volume] (viral load) in Blood by NAA with probe detection

0.00

0.0

7.9

—

(37020300) Entamoeba histolytica DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(4094501)

0.00

0.0

1.0

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.1

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

0.0

2.5

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

0.0

2.5

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3032185) JC virus DNA [#/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

8.3

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

1.2

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.90

0.00

1.0

2.5

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.1

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

0.96

0.00

2.5

2.1

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.0

1.2

—

172.7

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

6.2

—

0.7

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

1.0

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.6

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

0.5

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.98

0.00

2.0

1.5

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.5

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.1

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

0.0

1.0

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.0

—

13.5

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3027944) Amphetamines [Presence] in Urine

0.91

0.00

1.1

2.1

—

(3005593) Pancreatic islet cell Ab [Titer] in Serum

0.00

0.0

1.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.96

0.00

2.5

2.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.1

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.7

—

32.7

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.2

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.0

1.1

—

140.2

—

(4027681)

0.00

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.1

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.1

—

(3021578) Parainfluenza virus 2 Ag [Presence] in Specimen

0.00

0.0

1.5

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3005880) Parainfluenza virus 3 Ag [Presence] in Specimen

0.00

0.0

1.5

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

2.0

—

(3006462) Nitrate [Presence] in Urine

0.00

0.0

1.4

—

(3005791) Eosinophil cationic protein (ECP) [Mass/volume] in Serum

0.00

0.0

2.1

—

18.4

—

(3011048) Pyruvate [Moles/volume] in Blood

0.00

0.0

1.1

—

104.7

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

0.0

2.2

—

(3001820) Epstein Barr virus nuclear Ab [Presence] in Serum

0.00

0.0

2.2

—

(3000012) Reticulocyte production index

0.00

0.0

1.0

—

(3002619) Bacteria identified in Specimen by Culture

0.00

0.0

1.2

—

(4034850)

0.00

-0.00

0.0

5.1

—

(3032390) JC virus DNA [#/volume] (viral load) in Urine by NAA with probe detection

0.00

-0.00

0.0

6.1

—

(3045424) Erythrocytes [Presence] in Urine

0.00

-0.00

0.0

1.6

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk

0.00

-0.00

0.0

1.1

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.4

—

(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3003752) BK virus DNA [Units/volume] (viral load) in Urine by NAA with probe detection

0.00

-0.00

0.0

6.1

—

(3005011) Chlamydia sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: P16_DISORD_RELATED_LONG_GESTATION_HIGH_BIRTHWGHTT – Disorders related to long gestation and high birth weight

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorders related to long gestation and high birth weight

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints