brain neoplasm: A neoplasm (disease) that involves the brain.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
433 |
4. Check minimum number of eventsNone |
433 |
5. Include endpointsNone |
433 |
6. Filter based on genotype QC (FinnGen only) |
413 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D13
- Name in latin
- Neoplasma benignum oesophagi
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Oesophagus
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 2379 | 1167 | 1194 |
| Only index persons | 2084 | 1051 | 1033 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.03 | 0.03 | 0.03 |
| Only index persons | 0.04 | 0.04 | 0.04 |
| Median age at first event (years) | |||
| Whole population | 61.50 | 61.77 | 61.20 |
| Only index persons | 60.86 | 60.89 | 60.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 413 | 223 | 190 |
| Unadjusted period prevalence (%) | 0.08 | 0.08 | 0.09 |
| Median age at first event (years) | 61.61 | 59.75 | 63.80 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 433
- Matched controls
- 4330
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
+∞
307.7
421
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
15.9
160.5
348
887
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
24.2
89.1
66
32
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
40.4
76.1
47
13
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
30.6
72.9
49
18
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
510.1
47.3
46
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
5.3
44.8
109
259
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
11.6
43.6
47
45
UJD02
NOMESCO Finland
Gastroscopy
6.8
39.0
67
114
R13
ICD-10 Finland
Dysphagia
5.6
37.7
81
171
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
4.8
30.9
80
197
K22.7
ICD-10 Finland
Barrett oesophagus
12.3
29.4
30
26
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
27.6
28.0
38
15
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
276.2
26.0
26
*
K22.1
ICD-10 Finland
Ulcer of oesophagus
9.1
23.9
30
35
A02BC05
ATC
esomeprazole; systemic
2.8
23.9
234
1291
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.9
23.6
81
244
R4190
NOMESCO Finland
Nutritional therapy
7.1
22.5
35
53
UJF32
NOMESCO Finland
Coloscopy
2.8
22.0
163
774
A02BC02
ATC
pantoprazole; systemic
3.1
20.3
345
2431
UJC12
NOMESCO Finland
Flexible oesophagoscopy
28.7
20.3
27
10
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
18.9
16.7
25
14
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
49.5
16.1
19
*
A02BC01
ATC
omeprazole; systemic
2.4
15.8
158
842
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
21.0
15.3
22
11
Z2221
NOMESCO Finland
Medical doctor
2.3
14.1
146
782
WX002
NOMESCO Finland
Sedation and analgesia
2.5
14.0
114
550
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
13.9
124
622
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
55.2
13.9
16
*
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
12.6
13.8
24
20
K22.2
ICD-10 Finland
Oesophageal obstruction
15.4
13.7
22
15
A02BC03
ATC
lansoprazole; oral
2.2
13.6
161
909
JCA05
NOMESCO Finland
Endoscopic polypectomy in oesophagus
144.3
13.5
14
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
13.4
123
625
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
13.3
92
410
WX402
NOMESCO Finland
General anaesthesia
2.4
13.1
113
557
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
13.0
234
1548
D64.9
ICD-10 Finland
Anaemia, unspecified
2.9
12.8
67
258
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.6
12.6
44
133
JN4BD
NOMESCO Finland
Extensive body CT
2.8
12.3
70
282
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
12.1
93
434
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.2
11.7
50
171
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
4.2
11.7
32
81
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
11.5
172
1050
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
123.2
11.5
12
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.5
11.2
40
122
JN4AD
NOMESCO Finland
Body CT examination
2.8
11.1
62
247
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.5
11.0
75
330
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.3
11.0
106
545
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
12.4
10.9
19
16
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
10.9
131
735
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
3.5
10.8
38
115
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
61.6
10.7
12
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.5
10.4
37
113
K92.1
ICD-10 Finland
Melaena
3.4
10.1
37
115
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
9.9
103
544
UJF30
NOMESCO Finland
Ileoscopy through colon
2.6
9.7
58
239
C16.00
ICD-10 Finland
Cardia
56.3
9.7
11
*
K29.3
ICD-10 Finland
Chronic superficial gastritis
4.3
9.6
25
61
N03AX16
ATC
[U] pregabalin
2.0
9.3
121
693
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.1
9.2
103
557
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
9.2
129
759
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
9.1
45
168
K90.0
ICD-10 Finland
Coeliac disease
4.2
8.9
24
60
Z3226
NOMESCO Finland
Physiotherapist
2.1
8.8
96
514
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
20.5
8.5
12
6
K20
ICD-10 Finland
Oesophagitis
6.9
8.5
20
30
WX004
NOMESCO Finland
Patient-controlled sedation
91.8
8.4
9
*
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
8.4
95
516
JCA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in oesophagus
+∞
8.4
8
*
Z3231
NOMESCO Finland
Registered nurse
1.9
8.3
132
806
H02AB06
ATC
prednisolone; systemic
1.8
8.3
215
1530
K30
ICD-10 Finland
Functional dyspepsia
2.4
8.3
62
284
WX600
NOMESCO Finland
Single shot through catheter
7.8
8.2
18
24
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
8.2
52
220
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
17.6
8.1
12
7
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
9.2
8.1
16
18
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.5
7.9
28
85
UJC02
NOMESCO Finland
Rigid oesophagoscopy
11.1
7.8
14
13
JCA98
NOMESCO Finland
Other local endoscopic operation on oesophagus
45.8
7.7
9
*
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
7.7
60
279
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
12.1
7.6
13
11
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
25.5
7.6
10
*
130
Kela drug reimbursment
Malignant tumour
2.4
7.6
53
235
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
7.5
83
446
C03CA01
ATC
furosemide; systemic
1.8
7.4
150
983
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.6
7.4
43
174
J02AC01
ATC
fluconazole; systemic
1.8
7.4
167
1132
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.6
7.2
17
38
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.4
7.2
53
241
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
20.4
7.2
10
5
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
12.3
7.1
12
10
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.3
7.1
55
256
R12
ICD-10 Finland
Heartburn
2.6
7.0
41
167
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
7.7
7.0
15
20
A02BA02
ATC
ranitidine; systemic
1.9
6.9
99
580
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
6.9
171
1183
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
6.9
65
327
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.7
6.9
37
144
R03BA01
ATC
beclometasone; inhalant
2.1
6.9
69
356
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
6.8
26
83
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
17.0
6.8
10
6
R4110
NOMESCO Finland
Physiotherapy
1.8
6.7
130
837
H02AB07
ATC
prednisone; oral
2.1
6.7
68
352
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.8
6.7
20
54
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
6.6
162
1116
N02BE01
ATC
paracetamol; systemic, rectal
2.2
6.6
385
3388
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
6.6
59
291
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
6.6
124
792
8140/3-C15.9
ICD-O-3
Adenocarcinoma, NOS, of esophagus, NOS
70.9
6.4
7
*
K22.8
ICD-10 Finland
Other specified diseases of oesophagus
70.9
6.4
7
*
L17
ICPC
Foot/toe symptom/complaint
1.8
6.3
133
875
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
11.2
6.3
11
10
ZXE00
NOMESCO Finland
One hour or less
1.7
6.3
169
1189
R53
ICD-10 Finland
Malaise and fatigue
1.8
6.3
110
686
R06.0
ICD-10 Finland
Dyspnoea
1.8
6.3
127
827
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
27.1
6.2
8
*
D07AD01
ATC
clobetasol; topical
2.0
6.2
76
421
OAB50, ,
SPAT
2.8
6.2
31
116
WX882
NOMESCO Finland
High dependency care
4.1
6.2
17
43
E66.8
ICD-10 Finland
Other obesity
3.1
6.2
26
88
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.5
6.2
21
62
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
6.1
90
531
R02
ICPC
Shortness of breath/dyspnoea
2.1
6.0
63
330
E87.6
ICD-10 Finland
Hypokalaemia
3.2
6.0
24
79
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
259
1554
2.66
21.63
7.8
4.8
34.98
35.51
g/l
0.81
242
1452
291
1911
2.59
19.17
7.9
6.5
11.06
11.16
umol/l
0.06
280
1805
200
1133
2.42
17.84
3.1
2.5
54.98
131.48
u/l
0.56
181
1053
369
2785
3.20
17.53
10.4
7.6
82.06
78.99
u/l
0.43
346
2601
89
341
3.03
17.44
2.8
2.4
0.21
0.21
g/l
0.08
81
321
103
437
2.78
16.69
11.3
5.9
1.06
1.03
mmol/l
0.85
96
402
164
880
2.39
16.19
2.9
2.0
3.02
3.18
mg/l
0.36
148
752
264
1751
2.30
15.60
18.6
14.2
1.23
1.26
inr
0.17
60
523
265
1795
2.23
14.40
12.2
6.5
1.21
1.21
mmol/l
0.05
227
1524
249
1648
2.20
14.31
11.4
5.6
1.22
1.21
mmol/l
0.09
224
1496
289
2097
2.14
12.27
9.8
4.7
6.73
6.77
mmol/l
0.12
269
1959
70
288
2.71
11.79
13.6
8.4
9.70
9.94
mmol/l
0.10
63
276
242
1668
2.02
11.53
8.4
5.9
25.92
27.32
%
1.21
224
1559
277
2013
2.04
11.26
11.7
9.5
4.36
4.11
e9/l
0.92
240
1775
108
563
2.22
10.79
3.7
2.3
10.53
13.29
umol/l
4.14
102
523
217
1476
1.94
10.36
4.2
2.7
113.46
130.03
ug/l
0.51
201
1348
142
837
2.04
10.23
4.4
2.4
—
—
—
0
0
232
1624
1.92
10.06
4.0
2.6
—
—
—
0
0
235
1653
1.92
10.03
8.4
5.6
58.73
57.66
%
0.65
217
1549
122
695
2.05
9.57
4.5
3.8
605.48
269.71
ng/l
0.30
94
556
64
279
2.52
9.53
3.1
3.2
215.33
201.94
ng/l
0.10
58
251
71
330
2.38
9.19
2.7
2.4
34.11
31.49
u/l
0.33
53
279
142
877
1.92
8.72
1.9
1.5
21.26
21.19
nmol/l
0.02
127
732
212
1492
1.82
8.57
2.4
2.0
96.00
94.40
pmol/l
0.20
123
782
82
418
2.19
8.51
16.3
6.8
5.10
5.13
kpa
0.13
76
399
82
418
2.19
8.51
16.3
6.8
11.78
12.13
kpa
0.25
76
400
81
414
2.18
8.34
16.4
6.9
1.32
1.19
mmol/l
0.10
67
331
90
485
2.08
8.07
4.0
2.4
18.51
22.69
%
2.77
77
419
294
2314
1.84
7.95
4.1
3.2
61.80
51.15
u/l
0.67
263
2142
56
251
2.41
7.83
2.0
1.6
—
—
—
0
0
79
410
2.13
7.80
3.2
3.0
6.72
8.97
umol/l
0.73
67
363
322
2647
1.84
7.10
5.1
4.1
15.13
12.06
mm/h
2.18
288
2415
168
1154
1.74
7.00
4.7
3.5
27.89
32.11
u/l
1.88
160
1100
54
255
2.28
6.70
5.2
3.6
116.19
82.12
ng/l
1.37
46
226
396
3521
2.46
6.69
26.7
14.7
22.37
24.43
mg/l
0.79
328
2767
77
420
2.01
6.62
2.8
4.4
7.11
39.99
ug/l
1.01
69
353
38
154
2.61
6.55
1.9
1.8
1.38
1.56
g/l
0.55
32
132
22
67
3.41
6.22
1.5
1.5
—
—
—
0
0
22
67
3.41
6.22
1.5
1.5
—
—
—
0
0
178
1292
1.64
5.77
4.0
3.2
—
—
—
0
0
146
1010
1.67
5.69
4.2
3.1
0.34
0.49
e6/l
0.69
109
762
171
1235
1.64
5.62
3.9
3.5
2.34
2.35
mmol/l
0.37
146
1081
193
1445
1.61
5.43
2.7
2.3
74.25
77.52
nmol/l
0.92
167
1270
33
139
2.49
5.28
1.3
2.2
—
—
—
0
0
221
1722
1.58
5.16
3.9
3.6
0.00
0.00
estimate
0.50
35
369
30
122
2.57
5.16
2.4
1.9
473.41
309.58
ug/l
0.28
30
114
366
3235
1.85
5.12
5.7
4.6
1.92
2.32
mu/l
0.53
337
2901
400
3655
2.24
4.91
31.7
17.0
139.44
139.66
mmol/l
1.06
392
3551
400
3663
2.21
4.75
32.1
17.2
3.96
3.98
mmol/l
0.95
392
3557
219
1725
1.55
4.74
5.5
4.9
0.00
0.00
estimate
0.50
34
342
94
609
1.69
4.58
3.4
2.8
0.93
1.07
e6/l
0.11
48
345
220
1746
1.53
4.52
3.9
3.7
0.00
0.01
estimate
0.50
32
330
105
704
1.65
4.49
2.0
1.7
1156.53
1201.20
nmol/l
0.16
76
524
27
112
2.50
4.48
1.6
1.5
307.30
284.79
ug/g
0.27
22
64
103
692
1.64
4.36
3.3
3.1
2.46
2.45
mmol/l
0.34
86
608
88
571
1.68
4.25
3.5
3.0
3.02
2.10
e6/l
0.30
43
310
308
2651
1.56
4.20
4.5
3.8
14.55
14.88
pmol/l
1.54
287
2361
131
943
1.56
4.13
2.8
2.7
3421.15
6080.20
umol/l
0.35
113
810
342
3030
1.61
3.97
31.5
17.7
15.26
15.05
%
0.28
337
2988
105
741
1.55
3.56
1.4
1.2
0.58
1.48
u/ml
2.48
24
201
110
785
1.54
3.55
1.9
1.8
0.99
1.27
mg/l
1.05
81
622
147
1120
1.47
3.45
2.6
2.0
177.19
195.22
u/l
0.24
142
1047
13
42
3.16
3.40
1.3
1.3
—
—
—
0
0
24
110
2.25
3.25
1.1
1.2
—
—
—
0
0
87
601
1.56
3.23
2.2
1.9
—
—
—
0
0
65
420
1.64
3.17
2.1
1.8
—
—
—
0
0
178
1429
1.42
3.09
4.1
3.8
35.75
37.09
ng/l
0.06
118
1038
65
423
1.63
3.09
2.1
1.9
—
—
—
0
0
23
108
2.19
2.96
1.4
3.8
61.81
29.95
mg/l
0.73
18
86
23
108
2.19
2.96
1.4
3.8
63.51
113.58
mg/l
0.38
18
86
400
3760
1.84
2.91
15.7
10.6
25.40
25.75
u/l
0.21
385
3607
16
64
2.56
2.90
5.8
7.6
3905.40
416.67
iu/ml
—
5
12
145
1136
1.42
2.84
3.3
3.0
1489.88
1381.88
ng/l
0.16
116
966
20
91
2.26
2.78
1.5
1.7
—
—
—
0
0
17
72
2.42
2.76
1.5
1.5
—
—
—
0
0
23
112
2.11
2.72
1.1
1.2
—
—
—
0
0
409
3883
1.96
2.70
38.9
21.6
254.17
246.69
e9/l
1.23
400
3773
409
3884
1.96
2.68
38.9
21.6
4.38
4.48
e12/l
3.74
396
3765
409
3886
1.95
2.65
39.1
21.7
130.81
135.20
g/l
6.40
400
3817
373
3462
1.56
2.62
5.4
4.7
6.01
6.01
mmol/l
0.02
343
3130
47
295
1.67
2.58
2.9
2.7
57.50
65.46
ml/min/173m2
0.71
20
116
13
50
2.65
2.55
1.8
1.4
—
—
—
0
0
56
371
1.59
2.49
4.0
3.6
—
—
—
0
0
36
212
1.76
2.48
1.6
1.3
—
—
—
0
0
13
51
2.60
2.46
1.8
1.4
—
—
—
0
0
13
51
2.60
2.46
1.8
1.4
—
—
—
0
0
408
3884
1.87
2.46
40.9
21.7
39.27
40.18
%
2.20
369
3634
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
22
113
2.00
2.29
4.5
2.4
0.22
0.32
u/ml
—
10
60
16
73
2.24
2.24
3.2
2.7
13.74
16.02
%
—
9
36
12
48
2.54
2.20
1.8
1.4
—
—
—
0
0
80
588
1.44
2.19
1.4
1.3
29.92
34.14
iu/ml
0.11
33
194
36
221
1.69
2.17
2.0
1.6
—
—
—
0
0
13
55
2.41
2.14
1.2
1.3
—
—
—
0
0
139
1126
1.35
2.14
3.3
3.1
7.25
7.41
mmol/l
0.17
121
931
163
1354
1.33
2.11
3.9
3.8
—
—
—
0
0
7
20
3.54
2.06
1.7
2.0
—
—
—
0
0
12
50
2.44
2.04
1.8
1.4
—
—
—
0
0
12
50
2.44
2.04
1.8
1.4
—
—
—
0
0
55
381
1.51
2.03
1.9
1.6
1.89
1.51
%
1.03
43
326
21
112
1.92
2.00
1.8
1.8
—
—
—
0
0
16
79
2.06
1.87
2.7
2.2
109.55
128.29
g/l
2.02
11
57
45
304
1.54
1.87
8.2
4.1
1.23
1.22
mmol/l
0.37
39
267
8
28
2.89
1.87
1.6
1.3
—
—
—
0
0
5
12
4.20
1.83
1.0
2.8
591.00
743.42
u/ml
—
5
12
70
520
1.41
1.82
1.6
1.4
—
—
—
0
0
96
754
1.35
1.78
1.8
1.8
481.13
9516296.60
pmol/l
0.50
77
599
17
88
1.97
1.77
1.4
1.7
—
—
—
0
0
27
165
1.68
1.69
1.1
1.0
—
—
—
0
0
12
55
2.22
1.69
2.6
2.3
4.98
4.76
e9/l
0.14
12
55
47
329
1.48
1.67
2.0
2.5
6.59
8.23
ug/l
0.30
41
290
136
1135
1.29
1.64
4.1
3.9
6.58
8.91
mg/mmol
0.54
87
701
118
970
1.30
1.59
1.8
1.6
1.36
1.38
mmol/l
0.12
102
805
28
176
1.63
1.59
1.3
1.4
—
—
—
0
0
17
92
1.88
1.58
1.8
1.4
—
—
—
0
0
227
2024
1.26
1.56
3.1
2.8
—
—
—
0
0
351
3305
1.33
1.52
6.5
6.0
39.90
40.27
mmol/mol
0.30
315
3047
73
564
1.35
1.51
1.4
1.3
29.59
10.74
u/ml
0.70
31
228
12
58
2.10
1.50
2.7
2.7
63.92
58.48
%
1.24
12
58
18
102
1.80
1.47
1.3
1.5
—
—
—
0
0
33
221
1.53
1.46
4.5
3.4
3.37
2.07
mmol/l
0.90
26
167
19
111
1.74
1.41
1.3
1.3
31.74
26.17
iu/l
0.29
14
98
17
96
1.80
1.41
1.3
1.2
—
—
—
0
0
5
17
2.96
1.36
1.4
1.3
—
—
—
0
0
9
43
2.12
1.31
3.8
3.9
—
—
—
0
0
16
91
1.79
1.30
1.1
1.3
—
—
—
0
0
5
18
2.80
1.29
1.0
1.0
—
—
—
0
0
353
3349
1.29
1.27
4.1
4.1
1.27
1.28
mmol/l
0.09
316
3030
16
93
1.75
1.23
1.2
1.6
—
—
—
0
0
6
26
2.33
1.19
2.5
1.8
0.16
0.19
e9/l
—
6
20
16
94
1.73
1.19
1.4
1.3
—
—
—
0
0
91
751
1.27
1.19
4.0
4.0
1.01
1.02
kg/l
2.01
12
102
20
126
1.62
1.16
2.8
3.0
—
—
—
0
0
5
20
2.52
1.15
1.6
1.8
1.00
0.97
g/l
—
5
20
14
81
1.75
1.10
1.6
1.6
3.16
6.01
iu/l
—
5
24
14
82
1.73
1.06
1.5
1.1
—
—
—
0
0
7
33
2.14
1.06
1.1
1.4
339.00
296.34
u/l
—
7
33
364
3488
1.27
1.06
4.7
4.6
4.51
4.64
mmol/l
1.55
332
3187
15
91
1.67
1.02
1.5
1.4
—
—
—
0
0
9
48
1.89
1.01
1.3
1.6
—
—
—
0
0
9
48
1.89
1.01
1.3
1.6
—
—
—
0
0
5
23
2.19
0.98
2.0
1.7
—
—
—
0
0
361
3464
1.25
0.98
4.6
4.5
1.39
1.47
mmol/l
2.69
326
3153
9
52
1.75
0.93
1.2
1.2
—
—
—
0
0
9
52
1.75
0.93
1.1
1.1
—
—
—
0
0
19
277
0.67
0.91
1.9
1.7
—
—
—
0
0
369
3557
1.25
0.90
5.3
5.2
2.67
2.73
mmol/l
0.63
337
3234
6
29
2.08
0.89
1.5
1.1
—
—
—
0
0
350
3365
1.21
0.82
23.9
13.8
77.83
78.85
ml/min/173m2
0.35
295
2768
15
98
1.55
0.79
1.9
1.5
—
—
—
0
0
11
66
1.68
0.79
1.3
1.7
—
—
—
0
0
11
66
1.68
0.79
1.3
1.7
—
—
—
0
0
13
82
1.60
0.79
1.2
1.3
—
—
—
0
0
57
474
1.23
0.73
1.6
1.4
—
—
—
0
0
57
476
1.23
0.70
4.6
4.5
33.67
31.85
%
0.75
40
307
13
85
1.55
0.69
1.1
1.1
—
—
—
0
0
11
69
1.61
0.69
1.1
1.7
—
—
—
0
0
5
27
1.86
0.68
1.2
1.1
—
—
—
0
0
5
27
1.86
0.68
1.2
1.5
—
62.00
—
0
5
5
27
1.86
0.68
1.2
1.1
—
—
—
0
0
5
27
1.86
0.68
2.2
1.8
558.60
503.25
e6/l
—
5
20
14
95
1.49
0.65
1.2
1.6
—
—
—
0
0
12
79
1.53
0.63
1.2
1.2
—
—
—
0
0
8
51
1.58
0.60
2.4
1.9
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
8
53
1.52
0.58
1.3
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
23
0.00
0.58
0.0
1.2
—
—
—
0
0
14
195
0.71
0.57
1.9
2.9
0.13
0.13
e6/l
0.01
14
190
9
61
1.49
0.54
1.3
1.6
—
—
—
0
0
6
39
1.55
0.53
1.0
1.7
—
—
—
0
0
6
39
1.55
0.53
1.0
1.7
—
—
—
0
0
6
39
1.55
0.53
1.0
1.7
—
—
—
0
0
9
65
1.39
0.51
1.9
1.2
—
—
—
0
0
11
77
1.44
0.46
1.3
1.2
—
1.03
—
0
7
29
238
1.23
0.45
2.2
1.9
—
—
—
0
0
23
184
1.26
0.44
5.8
2.9
21.15
36.09
u/ml
1.11
23
178
9
129
0.69
0.44
1.2
1.7
4.17
3.88
mg/l
—
9
99
5
31
1.62
0.43
1.6
1.1
—
—
—
0
0
5
31
1.62
0.43
1.0
1.1
1.21
1.80
nmol/l
—
5
26
5
31
1.62
0.43
1.0
1.1
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
8
58
1.39
0.41
1.1
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
5
34
1.48
0.40
8.2
2.1
—
—
—
0
0
5
34
1.48
0.40
1.0
1.5
—
—
—
0
0
5
35
1.43
0.39
1.0
1.3
—
—
—
0
0
15
115
1.32
0.39
1.3
2.0
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
5
37
1.36
0.37
1.0
1.1
—
—
—
0
0
9
71
1.27
0.36
1.2
1.5
—
—
—
0
0
6
41
1.47
0.36
1.0
1.9
—
—
—
0
0
6
44
1.37
0.34
1.0
1.8
—
—
—
0
0
12
92
1.31
0.32
1.2
1.2
—
2.43
—
0
14
68
741
0.90
0.30
2.7
2.9
0.54
0.76
ug/l
2.52
48
490
7
54
1.30
0.30
1.3
1.6
—
—
—
0
0
12
94
1.28
0.28
1.4
1.5
—
—
—
0
0
12
94
1.28
0.28
1.2
1.2
—
2.29
—
0
18
9
73
1.24
0.25
1.4
1.2
—
37.05
—
0
8
5
39
1.29
0.23
1.0
1.1
—
—
—
0
0
5
41
1.22
0.22
1.4
1.4
0.55
0.40
nmol/l
—
5
32
5
42
1.19
0.21
1.2
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.1
—
2.37
—
0
6
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
52
1.16
0.19
1.2
1.1
—
—
—
0
0
5
68
0.73
0.17
1.4
1.5
—
—
—
0
0
6
79
0.76
0.15
1.2
1.3
—
245.91
—
0
37
8
99
0.80
0.14
2.4
1.7
—
—
—
0
0
122
1258
0.96
0.13
4.7
4.9
1.43
2.70
ug/l
3.14
107
1116
11
96
1.15
0.10
2.8
2.5
33.83
113.64
ug/min
—
6
57
6
56
1.07
0.08
1.0
1.6
—
—
—
0
0
23
215
1.07
0.07
2.2
1.8
—
—
—
0
0
98
961
1.03
0.05
4.8
3.9
0.00
0.00
estimate
0.50
31
337
100
1017
0.98
0.05
3.9
4.3
21.39
20.94
%
0.10
46
490
14
134
1.05
0.00
2.4
1.6
—
—
—
0
0
21
216
0.97
0.00
1.2
1.2
154.96
135.19
iu/ml
—
7
89
47
464
1.01
0.00
8.5
6.8
—
—
—
0
0
15
146
1.03
0.00
2.5
1.8
—
—
—
0
0
6
69
0.87
-0.00
1.2
1.1
123.92
37.03
u/l
—
6
61
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
84
0.95
-0.00
1.1
1.4
3.75
3.84
mmol/l
—
8
78
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
1.28
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
22.79
—
0
7
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
-0.00
1.4
1.4
—
—
—
0
0
8
85
0.94
-0.00
1.1
1.5
8.00
1427.04
e6/l
—
8
70
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
85
0.94
-0.00
1.1
1.4
1.63
15.29
e6/l
—
8
68
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
4.12
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_OESOPHAGUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OESOPHAGUS | 1.743 [1.42, 2.14] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.605 |
During the follow-up period (1.1.1998 — 31.12.2019), 220 out of 904 females with CD2_BENIGN_OESOPHAGUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_OESOPHAGUS | 2.397 [1.96, 2.94] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.005 |
During the follow-up period (1.1.1998 — 31.12.2019), 354 out of 951 males with CD2_BENIGN_OESOPHAGUS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_OESOPHAGUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.182% | 0.547% |
| 5 | 1.21% | 2.914% |
| 10 | 2.852% | 6.638% |
| 15 | 5.388% | 13.23% |
| 20 | 9.566% | 20.951% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_OESOPHAGUS – Benign neoplasm: Oesophagus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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