Other and unspecified mental retardation

F5_OTHRET

mental retardation: ['Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual is mentally retarded. IQ scores between 70 and 79 are in the borderline mentally retarded range. Scores below 67 are in the retarded range. (Joynt, Clinical Neurology, 1992, Ch55, p28)']

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F78, F79
  • Hospital discharge: ICD-9 3199
  • Hospital discharge: ICD-8 315
  • Cause of death: ICD-10 F78, F79
  • Cause of death: ICD-9 3199
  • Cause of death: ICD-8 315

2 out of 7 registries used, show all original rules.

609

4. Check minimum number of events

None

609

5. Include endpoints

None

609

6. Filter based on genotype QC (FinnGen only)

549

Control definitions (FinnGen only)

Control exclude
F5_MENTRET

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 16429 6793 9614
Only index persons 12801 5334 7467
Unadjusted period prevalence (%)
Whole population 0.24 0.19 0.27
Only index persons 0.25 0.20 0.29
Median age at first event (years)
Whole population 7.92 9.25 6.90
Only index persons 9.82 11.70 8.48

-FinnGen-

Key figures

All Female Male
Number of individuals 549 255 294
Unadjusted period prevalence (%) 0.11 0.09 0.13
Median age at first event (years) 10.36 12.81 8.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
609
Matched controls
6047
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
1398.8
307.7
295
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
14.6
181.6
191
184
N03AG01
ATC
valproic acid; systemic, rectal
14.1
180.4
195
196
P85
ICPC
Mental retardation
680.7
163.8
155
*
N05BA09
ATC
clobazam; oral
39.0
161.5
102
31
G40.9
ICD-10 Finland
Epilepsy, unspecified
15.5
130.2
123
97
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
+∞
126.3
117
*
F83
ICD-10 Finland
Mixed specific developmental disorders
13.8
121.1
123
109
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
8.0
119.4
205
360
N05AX08
ATC
risperidone; systemic
9.6
118.1
162
219
183
Kela drug reimbursment
Lamotrigin and topiramate
30.3
117.9
80
30
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
53.3
115.4
67
14
N03AX14
ATC
levetiracetam; systemic
14.8
109.6
105
84
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
1197.8
106.4
101
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
15.8
103.8
95
70
F79.1
ICD-10 Finland
Unspecified mental retardation, significant impairment of behaviour requiring attention or treatment
+∞
85.2
80
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
7.2
83.3
145
252
EBA15
NOMESCO Finland
Extraction of multiple teeth
10.3
82.5
100
113
N05CD08
ATC
midazolam; nasal, systemic
11.0
82.5
95
100
N05BA01
ATC
diazepam; systemic, rectal
6.5
80.6
158
309
N03AX09
ATC
lamotrigine; oral
8.9
79.6
109
144
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
7.9
77.9
121
185
R62.0
ICD-10 Finland
Delayed milestone
8.5
76.0
109
152
N05AA02
ATC
levomepromazine; systemic
10.6
68.7
80
85
N03AX11
ATC
topiramate; oral
12.0
65.8
70
65
113
Kela drug reimbursment
Anxiety disorders associated with mental retardation
+∞
65.7
62
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.5
65.4
151
340
F71.0
ICD-10 Finland
Moderate mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
63.5
60
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
14.5
59.0
55
41
R56.8
ICD-10 Finland
Other and unspecified convulsions
6.0
58.4
117
230
3199A
ICD-9 Finland
Unspecified mental retardation[MUU ÄLYLLINEN KEHITYSVAMMAISUUS,EI KÄYTTÄYTYMIHÄIRI]
+∞
56.0
53
*
F78.0
ICD-10 Finland
Other mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
56.0
53
*
A06AD11
ATC
lactulose; oral
5.8
55.1
115
234
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
+∞
54.9
52
*
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
4.7
53.3
150
394
N05AH03
ATC
olanzapine; systemic
6.0
52.4
103
198
H50.30
ICD-10 Finland
Intermittent esotropy
14.8
51.2
47
34
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
14.8
51.2
47
34
31599
ICD-8 Finland
Unspecified mental retardation, Other and unspecified
+∞
50.6
48
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
12.2
49.3
51
45
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
513.8
49.0
48
*
N05AC02
ATC
thioridazine; oral
15.1
48.6
44
31
XA800
NOMESCO Finland
Neuropsychological investigation
5.2
48.5
115
261
N03AF02
ATC
oxcarbazepine; oral
7.1
48.0
77
120
N05BA06
ATC
lorazepam; systemic, sublingual
8.6
47.7
64
81
RL140, ,
NOMESCO Finland
14.6
47.7
44
32
N03AG04
ATC
vigabatrin; oral
94.0
47.5
52
6
A28
ICPC
Limited function/disability NOS
4.7
46.8
125
313
N03AF01
ATC
carbamazepine; oral, rectal
8.1
45.4
64
86
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.6
44.5
200
725
F29
ICD-10 Finland
Unspecified nonorganic psychosis
6.7
43.8
75
125
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
10.9
43.3
48
47
F72.0
ICD-10 Finland
Severe mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
42.1
40
*
Z2446
NOMESCO Finland
Social worker
3.8
41.6
156
499
Z31.5
ICD-10 Finland
Genetic counselling
4.7
40.7
107
263
181
Kela drug reimbursment
Retigabine and vigabatrin
114.7
40.2
43
*
F79
ICD-10 Finland
Unspecified mental retardation
+∞
39.9
38
*
L28
ICPC
Limited function/disability (L)
4.4
39.9
117
313
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.3
36.7
107
284
RT150, ,
NOMESCO Finland
12.2
36.1
37
32
N03AE01
ATC
clonazepam; systemic
6.4
34.2
60
102
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
10.3
33.9
39
40
N04AA02
ATC
biperiden; systemic
11.8
33.6
35
31
F71.1
ICD-10 Finland
Moderate mental retardation, significant impairment of behaviour requiring attention or treatment
+∞
33.6
32
*
N05AF03
ATC
chlorprothixene; systemic
8.6
33.5
44
54
N05AD01
ATC
haloperidol; systemic
10.8
33.4
37
36
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.2
33.0
169
650
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
11.1
32.2
35
33
N05AB03
ATC
perphenazine; systemic, rectal
7.8
31.9
46
63
SPAT1229
SPAT
Assessment of need for aid
6.4
31.8
55
92
Z2445
NOMESCO Finland
Psychologist
3.8
30.4
105
313
N05AH02
ATC
clozapine; systemic
8.2
29.8
41
53
H50.0
ICD-10 Finland
Convergent concomitant strabismus
8.5
28.7
38
47
Z3229
NOMESCO Finland
Other healthcare associate professional
3.5
28.4
112
364
RS222, ,
NOMESCO Finland
9.0
28.4
36
42
JDB10
NOMESCO Finland
Percutaneous gastrostomy
10.4
28.3
32
32
U04
ICPC
Incontinence urine
7.4
28.1
42
60
TJD20
NOMESCO Finland
Change of gastrostomy tube
10.8
28.0
31
30
G40.89
ICD-10 Finland
Other epilepsy
27.8
27.3
37
14
RL130, ,
NOMESCO Finland
9.1
27.2
34
39
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
9.8
27.1
32
34
WYA30, ,
SPAT
9.5
26.5
32
35
RT490, ,
NOMESCO Finland
34.5
25.7
33
10
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.6
25.5
206
993
Z3226
NOMESCO Finland
Physiotherapist
2.7
25.4
186
854
M41.4
ICD-10 Finland
Neuromuscular scoliosis
52.1
25.4
30
6
M03BX01
ATC
baclofen; systemic
10.7
25.3
28
27
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.4
25.2
102
336
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
60.3
25.1
29
5
M79.0
ICD-10 Finland
Rheumatism, unspecified
7.7
25.0
36
49
N05AH04
ATC
quetiapine; oral
2.8
23.8
148
623
N03AF03
ATC
rufinamide; oral
247.6
23.7
24
*
SPAT1262
SPAT
Handing over of treatment supplies
3.2
23.7
109
388
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
20.4
23.6
35
18
H52.2
ICD-10 Finland
Astigmatism
4.8
23.4
56
126
R1260
NOMESCO Finland
Evaluation of communicative skills
7.3
23.3
35
50
P72
ICPC
Schizophrenia
7.5
23.3
34
47
K03.66
ICD-10 Finland
Tooth plaque
3.0
23.2
123
475
N05AX12
ATC
aripiprazole; systemic
4.5
23.1
60
144
OAB43, ,
SPAT
0.2
23.1
25
1280
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
67.2
22.9
26
*
F84.0
ICD-10 Finland
Childhood autism
31.2
22.9
30
10
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.4
22.4
88
284
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
5.1
21.7
47
97
WYA20
NOMESCO Finland
Home visit
9.0
21.5
27
31
RT274, ,
NOMESCO Finland
51.6
21.2
25
5
G03DC03
ATC
lynestrenol; oral
7.9
20.8
29
38
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.5
20.5
161
755
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
8.5
20.5
27
33
Q99.8
ICD-10 Finland
Other specified chromosome abnormalities
19.5
20.1
30
16
N88
ICPC
Epilepsy
21.5
20.0
29
14
F71.9
ICD-10 Finland
Moderate mental retardation, without mention of impairment of behaviour
+∞
19.8
19
*
N06AB04
ATC
citalopram; systemic
2.8
19.4
114
462
R11
ICD-10 Finland
Nausea and vomiting
2.9
19.3
100
379
K59.09
ICD-10 Finland
Constipation, unspecified
3.5
19.2
72
225
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.6
19.0
132
582
31099
ICD-8 Finland
Borderline mental retardation, Other and unspecified
+∞
18.8
18
*
F78.1
ICD-10 Finland
Other mental retardation, significant impairment of behaviour requiring attention or treatment
+∞
18.8
18
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
14.7
18.7
31
22
199
Kela drug reimbursment
Rufinamide
194.4
18.6
19
*
R4130
NOMESCO Finland
Speech therapy
4.0
18.5
56
151
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
18.3
146
686
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
53.9
18.0
21
*
N05BA04
ATC
oxazepam; oral
2.5
18.0
142
664
WX402
NOMESCO Finland
General anaesthesia
2.3
17.9
189
1002
3046, ,
Kela drug reimbursment
+∞
17.7
17
*
U07
ICPC
Urine symptom/complaint other
3.9
17.7
54
146
P99
ICPC
Psychological disorders other
5.1
17.6
38
78
RT190, ,
NOMESCO Finland
24.7
17.4
24
10
SAA03
NOMESCO Finland
Extended examination of mouth
2.1
17.4
338
2263
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
17.3
233
1359
G40.39
ICD-10 Finland
Other or unspecified generalized epileptic syndromes with atonic, clonic, myoclonic or tonic-clonic seizures
15.3
17.2
28
19
DFF20
NOMESCO Finland
Audiometry for children
4.9
17.1
39
84
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
16.8
105
438
N03AX24
ATC
cannabidiol; oral
+∞
16.7
16
*
F72.1
ICD-10 Finland
Severe mental retardation, significant impairment of behaviour requiring attention or treatment
+∞
16.7
16
*
F71
ICD-10 Finland
Moderate mental retardation
+∞
16.7
16
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.6
16.7
59
177
7834D
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[LAPSEN NORMAALIN KEHITTYMISEN HIDASTUMINEN]
173.4
16.5
17
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.1
16.2
72
249
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
6.7
16.2
26
40
UDC00
NOMESCO Finland
Ear microscopy
3.1
15.9
73
257
4122
FHL
Tympanostomy (tympanic tube)
6.3
15.9
27
44
ZXE00
NOMESCO Finland
One hour or less
2.0
15.9
272
1722
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.7
15.8
53
153
R4110
NOMESCO Finland
Physiotherapy
2.1
15.7
201
1142
31199
ICD-8 Finland
Mild mental retardation, Other and unspecified
+∞
15.6
15
*
H47.7
ICD-10 Finland
Disorder of visual pathways, unspecified
+∞
15.6
15
*
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
22.6
15.6
22
10
N03AX18
ATC
lacosamide; systemic
12.7
15.4
27
22
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.8
14.9
47
130
4451
FHL
Guitar cutting
4.2
14.9
41
103
N03AX15
ATC
zonisamide; oral
18.8
14.7
22
12
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
+∞
14.6
14
*
1530, ,
Kela drug reimbursment
+∞
14.6
14
*
F73.0
ICD-10 Finland
Profound mental retardation, with the statement of no, or minimal, impairment of behaviour
+∞
14.6
14
*
3459X
ICD-9 Finland
Epilepsy, unspecified
36.8
14.5
18
5
H52.0
ICD-10 Finland
Hypermetropia
3.7
14.5
47
133
G40.09
ICD-10 Finland
Other or unspecified partial (focal) idiopathic epilepsy or epileptic syndrome with local onset
15.8
14.4
23
15
SPAT1234
SPAT
Support of social functional capacity
4.8
14.2
33
72
R5110, ,
SPAT
4.4
14.1
36
85
G40.10
ICD-10 Finland
Simple partial seizures
14.8
14.1
23
16
EBA00
NOMESCO Finland
Extraction of tooth
1.9
14.1
262
1688
N06AA09
ATC
amitriptyline; systemic
3.5
14.0
51
156
C03CA01
ATC
furosemide; systemic
2.5
13.9
98
431
K59.0
ICD-10 Finland
Constipation
3.5
13.8
49
147
SDA02
NOMESCO Finland
Periodontal treatment, brief
2.0
13.8
241
1518
N39.4
ICD-10 Finland
Other specified urinary incontinence
3.9
13.7
42
114
R32
ICD-10 Finland
Unspecified urinary incontinence
5.8
13.6
25
44
H50.31
ICD-10 Finland
Intermittent exotropia
4.6
13.6
33
75
3170A
ICD-9 Finland
Mild mental retardation[LIEVÄ ÄLYLL.KEHITYSVAMMAISUUS,EI KÄYTÄYTYM.HÄIRIÖTÄ]
+∞
13.6
13
*
3199B
ICD-9 Finland
Unspecified mental retardation[MUU ÄLYLLINEN KEHITYSVAMMAISUUS JA KÄYTTÄYTYMIHÄIRI]
+∞
13.6
13
*
ADB00
NOMESCO Finland
Implantation of vagus nerve stimulating device
34.7
13.5
17
5
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.5
13.5
90
386
R33
ICD-10 Finland
Retention of urine
4.3
13.4
35
84
N03AX22
ATC
perampanel; oral
18.6
13.4
20
11
ZXD10
NOMESCO Finland
Scheduled procedure
1.9
13.4
245
1563
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.8
13.3
71
272
N03AB02
ATC
phenytoin; systemic
14.1
13.3
22
16
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.8
13.3
73
284
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
2.6
13.1
86
365
R4120
NOMESCO Finland
Occupational therapy
2.8
13.1
69
262
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
13.1
74
292
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
23.0
12.9
18
8
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.6
12.8
78
319
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.0
12.7
*
302
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
12.7
104
489
T90
ICPC
Diabetes non-insulin dependent
2.4
12.7
94
423
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
5.6
12.6
24
44
F61.0
ICD-10 Finland
Mixed personality disorders
6.1
12.6
22
37
G41.9
ICD-10 Finland
Status epilepticus, unspecified
17.7
12.5
19
11
N03AX17
ATC
stiripentol; oral
+∞
12.5
12
*
F78.9
ICD-10 Finland
Other mental retardation, without mention of impairment of behaviour
+∞
12.5
12
*
V628A
ICD-9 Finland
Other psychosocial circumstances, Other psychological or physical stress, not elsewhere classified
+∞
12.5
12
*
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
13.5
12.5
21
16
N05CD07
ATC
temazepam; oral
3.3
12.3
48
153
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
3.9
12.3
37
99
Z50.5
ICD-10 Finland
Speech therapy
3.2
12.3
51
169
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
14.6
12.3
20
14
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
27.1
12.1
16
6
Q90.9
ICD-10 Finland
Down syndrome, unspecified
27.1
12.1
16
6
A10BA02
ATC
metformin; oral
2.3
12.0
108
528
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
12.0
139
751
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
12.0
197
1204
N05AF05
ATC
zuclopenthixol; systemic
14.9
11.8
19
13
ZXA10
NOMESCO Finland
Bilateral
2.2
11.7
117
596
N99
ICPC
Neurological disease other
16.7
11.7
18
11
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
30.5
11.6
15
5
34599
ICD-8 Finland
Epilepsy, Other and unspecified
30.5
11.6
15
5
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
65.8
11.6
13
*
31509
ICD-8 Finland
Unspecified mental retardation, Following infections and intoxications, Unspecified
+∞
11.5
11
*
F72.9
ICD-10 Finland
Severe mental retardation, without mention of impairment of behaviour
121.4
11.4
12
*
SAA02
NOMESCO Finland
Basic examination of mouth
2.0
11.4
473
3838
WX730
NOMESCO Finland
Conventional respirator
5.5
11.3
22
41
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.8
11.3
58
217
Q04.8
ICD-10 Finland
Other specified congenital malformations of brain
35.5
11.3
14
*
N05AC01
ATC
periciazine; systemic
35.5
11.3
14
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
11.2
76
327
Z2221
NOMESCO Finland
Medical doctor
1.9
11.0
183
1117
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
11.0
122
647
K08.3
ICD-10 Finland
Retained dental root
3.2
10.9
44
143
G80.8
ICD-10 Finland
Other cerebral palsy
43.8
10.9
13
*
N05AD03
ATC
melperone; systemic
15.7
10.8
17
11
N05AA01
ATC
chlorpromazine; systemic, rectal
10.8
10.8
20
19
XX4AW, ,
NOMESCO Finland
4.1
10.8
30
76
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
28.4
10.7
14
5
RS314, ,
NOMESCO Finland
28.4
10.7
14
5
F20.5
ICD-10 Finland
Residual schizophrenia
28.4
10.7
14
5
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
4.8
10.7
24
51
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.8
10.7
56
212
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.8
10.7
57
218
K05.18
ICD-10 Finland
Chronic gingivitis
2.7
10.6
62
248
H50.1
ICD-10 Finland
Divergent concomitant strabismus
8.1
10.6
23
29
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
0.2
10.6
11
616
R4190
NOMESCO Finland
Nutritional therapy
2.3
10.6
90
429
L17
ICPC
Foot/toe symptom/complaint
1.9
10.5
173
1050
H54.7
ICD-10 Finland
Unspecified visual loss
10.2
10.5
20
20
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
+∞
10.4
10
*
Q04.3
ICD-10 Finland
Other reduction deformities of brain
+∞
10.4
10
*
F70
ICD-10 Finland
Mild mental retardation
+∞
10.4
10
*
3170B
ICD-9 Finland
Mild mental retardation[LIEVÄ ÄLYLL.KEHITYSVAMMAISUUS,JOSSA KÄYTÄYTYM.HÄIRI]
+∞
10.4
10
*
WX892
NOMESCO Finland
Monitored bed care
2.5
10.4
68
288
AA1AD
NOMESCO Finland
CT of head and brain
2.1
10.3
110
573
F22.0
ICD-10 Finland
Delusional disorder
9.7
10.3
20
21
RS142, ,
NOMESCO Finland
19.0
10.3
15
8
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
23.7
10.2
14
6
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
13.3
10.2
17
13
SPAT1304
SPAT
Counselling and guidance related to ageing
4.4
10.0
25
58
TLC00
NOMESCO Finland
Insertion of intrauterine device
3.4
10.0
37
114
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
10.0
232
1560
F21
ICD-10 Finland
Schizotypal disorder
14.8
10.0
16
11
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
4.9
10.0
22
46
K02.1
ICD-10 Finland
Caries of dentine
1.8
9.9
377
2909
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
9.9
136
777
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.3
9.8
25
59
Z02.7
ICD-10 Finland
Issue of medical certificate
2.8
9.8
49
181
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
4.5
9.8
24
55
SPAT1301
SPAT
No procedures
1.8
9.7
170
1049
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
0.1
9.7
6
387
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
55.5
9.6
11
*
NF1DA
NOMESCO Finland
X-ray of hips
5.4
9.6
19
36
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
9.5
95
482
R55
ICD-10 Finland
Syncope and collapse
2.6
9.5
55
219
R50.9
ICD-10 Finland
Fever, unspecified
1.9
9.5
145
856
SCF02
NOMESCO Finland
Preventive oral care by dental hygienist
2.9
9.5
44
156
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
3.1
9.4
39
129
AA10D, ,
NOMESCO Finland
100.8
9.4
10
*
Q90.0
ICD-10 Finland
Trisomy 21, meiotic nondisjunction
30.3
9.4
12
*
R63.4
ICD-10 Finland
Abnormal weight loss
4.0
9.4
27
70
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
9.4
126
713
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.5
9.4
62
264
RT160, ,
NOMESCO Finland
8.2
9.4
20
25
7803A
ICD-9 Finland
General symptoms, Convulsions
8.2
9.4
20
25
R60.0
ICD-10 Finland
Localized oedema
2.6
9.3
54
215
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.8
9.3
21
45
A10BH01
ATC
sitagliptin; oral
3.2
9.3
37
120
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.7
9.2
49
187
Z39.2
ICD-10 Finland
Routine postpartum follow-up
0.1
9.2
5
353
S22
ICPC
Nail symptom/complaint
2.8
9.2
46
170
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.1
9.2
38
126
R1250
NOMESCO Finland
Evaluation of functional capability
4.2
9.2
24
58
B35.1
ICD-10 Finland
Tinea unguium
3.0
9.1
40
137
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.0
9.1
41
143
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
3.2
8.9
35
112
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.0
8.9
40
139
N28
ICPC
Limited function/disability (N)
8.1
8.9
19
24
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.6
8.8
51
203
K07.24
ICD-10 Finland
Open bite
3.6
8.8
29
83
P28
ICPC
Limited function/disability (P)
10.8
8.8
16
15
K02.9
ICD-10 Finland
Dental caries, unspecified
4.1
8.8
24
60
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.6
8.8
52
210
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.2
8.7
16
616
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
8.7
118
669
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
50.4
8.7
10
*
Q90
ICD-10 Finland
Down syndrome
50.4
8.7
10
*
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
50.4
8.7
10
*
SPAT1252
SPAT
Overall medication plan or its review
3.5
8.6
30
89
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
4.5
8.6
21
48
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
11.7
8.6
15
13
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
8.5
116
657
Z01.2
ICD-10 Finland
Dental examination
1.7
8.5
337
2583
N03AA02
ATC
phenobarbital; systemic
27.8
8.5
11
*
P94.2
ICD-10 Finland
Congenital hypotonia
20.2
8.5
12
6
F20.8
ICD-10 Finland
Other schizophrenia
20.2
8.5
12
6
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.8
8.4
26
71
C01AA05
ATC
digoxin; systemic
4.2
8.4
22
53
H61.2
ICD-10 Finland
Impacted cerumen
2.6
8.4
49
196
M03BX02
ATC
tizanidine; oral
0.6
8.4
134
2045
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.0
8.4
38
133
Z93.1
ICD-10 Finland
Gastrostomy status
12.9
8.4
14
11
B35.3
ICD-10 Finland
Tinea pedis
3.4
8.3
30
91
H47.6
ICD-10 Finland
Disorders of visual cortex
+∞
8.3
8
*
31500
ICD-8 Finland
Unspecified mental retardation, Following infections and intoxications, Post infectionem praenatalem
+∞
8.3
8
*
NEK20
NOMESCO Finland
Fenestration or forage of bone of pelvis
+∞
8.3
8
*
G82.4
ICD-10 Finland
Spastic tetraplegia
+∞
8.3
8
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.9
8.3
18
37
R62.8
ICD-10 Finland
Other lack of expected normal physiological development
4.7
8.3
19
41
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.8
8.3
169
1085
H13
ICPC
Plugged feeling ear
2.1
8.3
90
471
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.9
8.3
111
626
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
8.3
52
216
N30.0
ICD-10 Finland
Acute cystitis
2.2
8.2
76
374
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
3.8
8.2
25
68
U07.2
ICD-10 Finland
COVID-19, virus not identified
0.4
8.1
38
900
R03BB01
ATC
ipratropium bromide; inhalant
4.8
8.1
18
38
R5120
NOMESCO Finland
Preparation of an aid
4.8
8.1
18
38
30180
ICD-8 Finland
Personality disorders, Immatura
33.6
8.1
10
*
3AX01, ,
NOMESCO Finland
11.8
8.1
14
12
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
17.3
8.1
12
7
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
8.1
225
1572
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
8.0
154
970
OAA67, ,
SPAT
0.2
8.0
13
543
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.4
8.0
58
257
H47.2
ICD-10 Finland
Optic atrophy
10.1
8.0
15
15
Z3231
NOMESCO Finland
Registered nurse
1.7
8.0
208
1425
F22.9
ICD-10 Finland
Persistent delusional disorder, unspecified
22.2
8.0
11
5
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.9
8.0
37
131
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
13.2
7.9
13
10
N03AX23
ATC
brivaracetam; systemic
13.2
7.9
13
10
Q89.7
ICD-10 Finland
Multiple congenital malformations, not elsewhere classified
13.2
7.9
13
10
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
7.9
104
583
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
7.8
96
524
G91.1
ICD-10 Finland
Obstructive hydrocephalus
10.9
7.8
14
13
A29
ICPC
General symptom/complaint other
2.1
7.8
75
375
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
9.5
7.8
15
16
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
7.7
85
447
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
15.2
7.7
12
8
G40.11
ICD-10 Finland
Simple partial epileptic seizure that develops into a complex partial seizure
15.2
7.7
12
8
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
45.2
7.7
9
*
OAA65, ,
SPAT
0.3
7.7
19
619
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
0.2
7.7
8
369
-1, ,
ICPC
3.6
7.7
25
71
R56.0
ICD-10 Finland
Febrile convulsions
3.9
7.7
22
57
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.9
7.6
113
657
SPAT1240
SPAT
Therapeutic discussion
2.1
7.6
74
371
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
18.5
7.6
11
6
RS312, ,
NOMESCO Finland
18.5
7.6
11
6
H81
ICPC
Excessive ear wax
2.1
7.6
74
372
5210A
ICD-9 Finland
Diseases of hard tissues of teeth, Dental caries
25.2
7.6
10
*
A90
ICPC
Congenital anomaly NOS/multiple
25.2
7.6
10
*
RS211, ,
NOMESCO Finland
6.2
7.5
19
31
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
7.5
106
607
-31
ICPC
Medical examin/health eval partial
2.6
7.5
42
165
H52.1
ICD-10 Finland
Myopia
2.7
7.4
39
148
R13
ICD-10 Finland
Dysphagia
2.8
7.4
36
131
34510
ICD-8 Finland
Epilepsy, """"Grand mal""""
80.5
7.4
8
*
R5130, ,
SPAT
80.5
7.4
8
*
P91.02
ICD-10 Finland
Neonatal hypoxic-ischaemic encephalopathy, severe
80.5
7.4
8
*
29599
ICD-8 Finland
Schizophrenia, Unspecified type
80.5
7.4
8
*
EBA30
NOMESCO Finland
Extraction of root of tooth
3.2
7.4
29
93
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.5
7.4
18
41
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.3
7.4
58
267
OAB50, ,
SPAT
3.1
7.4
31
104
KMAK, ,
NOMESCO Finland
1.6
7.3
243
1763
G40
ICD-10 Finland
Epilepsy
6.9
7.3
17
25
31299
ICD-8 Finland
Moderate mental retardation, Other and unspecified
+∞
7.3
7
*
E77.1
ICD-10 Finland
Defects in glycoprotein degradation
+∞
7.3
7
*
31109
ICD-8 Finland
Mild mental retardation, Following infections and intoxications, Unspecified
+∞
7.3
7
*
Z37.0
ICD-10 Finland
Single live birth
0.1
7.3
*
233
ZXD05
NOMESCO Finland
Urgent procedure
1.7
7.3
165
1087
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.2
7.3
28
89
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
7.2
44
180
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
5.9
7.2
19
33
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
15.8
7.2
11
7
P21.0
ICD-10 Finland
Severe birth asphyxia
15.8
7.2
11
7
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
4.4
7.2
18
42
N05AN01
ATC
lithium; oral
3.7
7.2
22
60
3451A
ICD-9 Finland
Epilepsy, Generalised convulsive epilepsy
20.2
7.1
10
5
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
7.1
121
734
D12
ICPC
Constipation
3.3
7.1
26
80
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
12.1
7.1
12
10
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.8
7.1
21
56
A41.9
ICD-10 Finland
Sepsis, unspecified
3.0
7.0
31
107
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
6.9
46
196
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.7
6.9
37
142
WX882
NOMESCO Finland
High dependency care
2.1
6.9
66
329
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
13.9
6.9
11
8
T82
ICPC
Obesity
3.0
6.9
30
103
Z29
ICPC
Social problem NOS
3.5
6.8
23
67
U05
ICPC
Urination problems other
3.3
6.8
25
77
M01AB05
ATC
diclofenac; systemic, rectal
0.6
6.8
150
2135
Q65.0
ICD-10 Finland
Congenital dislocation of hip, unilateral
11.0
6.8
12
11
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
4.2
6.8
18
44
OAB48, ,
SPAT
0.3
6.8
14
505
TJF80
NOMESCO Finland
Ostomy education
6.2
6.8
17
28
P90
ICD-10 Finland
Convulsions of newborn
40.2
6.7
8
*
RF311, ,
NOMESCO Finland
40.2
6.7
8
*
G91.0
ICD-10 Finland
Communicating hydrocephalus
16.8
6.7
10
6
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.2
6.7
60
291
OAB95, ,
SPAT
0.2
6.7
5
285
WX704
NOMESCO Finland
Intubation
2.4
6.7
48
212
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
6.7
89
499
U71
ICPC
Cystitis/urinary infection other
2.9
6.7
31
110
SPAT1254
SPAT
Administration of medicine
1.9
6.6
93
531
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.3
6.5
47
208
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.8
6.5
120
743
OAA80, ,
SPAT
0.2
6.5
9
354
RS140, ,
NOMESCO Finland
10.1
6.5
12
12
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
6.9
6.5
15
22
XX4BW, ,
NOMESCO Finland
6.9
6.5
15
22
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
2.0
6.5
68
351
A02BC01
ATC
omeprazole; systemic
1.8
6.5
113
690
K05.30
ICD-10 Finland
Periodontitis complex
2.1
6.4
59
289
SDA03
NOMESCO Finland
Periodontal treatment
1.6
6.4
204
1455
A99
ICPC
Disease/condition unspecnature/site
2.2
6.4
53
249
G40.0
ICD-10 Finland
Localization-related (focal)(partial) idiopathic epilepsy and epileptic syndromes with seizures of localized onset
70.1
6.4
7
*
F72
ICD-10 Finland
Severe mental retardation
70.1
6.4
7
*
4304
FHL
Tooth or tooth extraction under general anesthesia
70.1
6.4
7
*
M79.7
ICD-10 Finland
Fibromyalgia
3.6
6.4
21
60
A03FA02
ATC
cisapride; oral, rectal
2.7
6.4
34
130
Z43.1
ICD-10 Finland
Attention to gastrostomy
14.4
6.4
10
7
F82
ICD-10 Finland
Specific developmental disorder of motor function
2.9
6.4
29
102
SDE03
NOMESCO Finland
Periodontal treatment by dental hygienist, extensive
1.8
6.3
107
646
SPAT1364
SPAT
Health check-up performed during second study year in students of upper secondary schools, vocational schools etc.
0.1
6.3
*
236
RS230, ,
NOMESCO Finland
8.2
6.3
13
16
H26.02
ICD-10 Finland
Presenil cataract
5.2
6.3
18
35
4121
FHL
Tympanic puncture or parasentosis in general anesthesia or operating room
6.0
6.3
16
27
3820A
ICD-9 Finland
Suppurative and unspecified otitis media, Acute suppurative otitis media
5.6
6.3
17
31
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.6
6.3
20
56
F05.9
ICD-10 Finland
Delirium, unspecified
9.3
6.3
12
13
N06AX03
ATC
mianserin; oral
3.2
6.3
24
76
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
3.3
6.3
23
71
34408
ICD-8 Finland
Other cerebral paralysis, Alia definita
+∞
6.2
6
*
7580A
ICD-9 Finland
Chromosomal anomalies, Down's syndrome
+∞
6.2
6
*
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
+∞
6.2
6
*
3180A
ICD-9 Finland
Other specified mental retardation, Moderate mental retardation[KESKIVAIKEA ÄLYLL KEHITYSVAMMAISUUS,EI KÄYTÄYT.HÄIR]
+∞
6.2
6
*
31550
ICD-8 Finland
Unspecified mental retardation, With chromosomal abnormalities, Morbus Down (mongolismi)
+∞
6.2
6
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.2
100
595
38110
ICD-8 Finland
Otitis media without mention of mastoiditis, Chronic
26.8
6.2
8
*
G93.4
ICD-10 Finland
Encephalopathy, unspecified
26.8
6.2
8
*
R45.1
ICD-10 Finland
Restlessness and agitation
26.8
6.2
8
*
29999
ICD-8 Finland
Unspecified psychosis
26.8
6.2
8
*
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
26.8
6.2
8
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
0.2
6.2
5
273
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
0.2
6.2
10
418
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
6.2
39
163
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
5.4
6.2
17
32
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.2
6.1
24
77
F84.8
ICD-10 Finland
Other pervasive developmental disorders
5.8
6.1
16
28
F40.2
ICD-10 Finland
Specific (isolated) phobias
5.8
6.1
16
28
DFF10
NOMESCO Finland
Measurement of acoustic impedance (tympanometry and reflex testing)
5.8
6.1
16
28
R10.0
ICD-10 Finland
Acute abdomen
4.0
6.1
17
43
OAA62, ,
SPAT
0.2
6.1
6
290
NFL22
NOMESCO Finland
Myotomy or tenotomy of hip or thigh
12.6
6.1
10
8
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
12.6
6.1
10
8
RD210, ,
NOMESCO Finland
2.5
6.1
38
158
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.7
6.1
114
710
JDB00
NOMESCO Finland
Gastrostomy
8.7
6.0
12
14
XCD00
NOMESCO Finland
Clinical examination of eye in general anaesthesia
8.7
6.0
12
14
N18
ICPC
Paralysis/weakness
8.7
6.0
12
14
Q53.2
ICD-10 Finland
Undescended testicle, bilateral
8.7
6.0
12
14
Y0599
ICD-8 Finland
Investigation of digestive system
8.7
6.0
12
14
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.2
6.0
49
229

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
137
90
19.21
161.11
5.8
4.9
442.50
372.24
umol/l
3.89
129
84
214
986
2.78
29.72
4.0
2.5
—
—
—
0
0
210
1008
2.63
26.38
4.7
4.7
—
—
—
0
0
363
2382
2.27
21.16
13.3
11.7
1.22
1.22
mmol/l
0.55
328
2154
64
174
3.96
20.90
2.4
4.0
36.47
37.07
umol/l
0.09
59
165
347
2255
2.23
20.46
13.5
12.3
1.22
1.23
mmol/l
0.74
333
2135
27
10
27.97
20.12
3.3
2.4
22.83
14.61
umol/l
—
27
10
251
1471
2.18
18.74
12.2
8.8
1.22
1.20
inr
0.15
69
410
273
1677
2.12
17.82
4.9
7.6
35.93
36.84
g/l
1.71
259
1613
382
2687
2.10
17.05
8.1
7.5
6.47
6.35
mmol/l
0.43
366
2520
199
1135
2.10
15.33
2.9
3.0
50.56
62.38
u/l
1.77
192
1073
304
2041
1.96
14.61
6.9
7.9
16.68
19.20
umol/l
0.52
288
1918
9
556
0.15
13.73
1.1
1.3
—
—
—
0
0
170
984
1.99
12.15
3.3
3.4
7.05
5.62
e6/l
0.61
154
884
405
3113
1.87
11.70
7.0
6.8
110.74
105.20
u/l
0.66
384
2941
544
4659
2.49
11.41
23.2
14.7
4.04
3.98
mmol/l
4.37
533
4532
182
1101
1.91
11.31
4.7
4.1
7.39
7.40
ph
1.10
40
190
231
1508
1.84
11.31
4.7
4.2
72.40
34.58
e6/l
0.48
185
1158
543
4653
2.46
11.26
23.5
14.7
139.35
139.49
mmol/l
0.53
534
4544
369
2783
1.80
11.04
6.1
3.9
178.75
140.78
e6/l
—
8
36
269
1854
1.79
10.90
3.2
3.2
77.76
72.49
nmol/l
2.06
255
1730
157
914
1.95
10.89
15.9
9.9
7.43
7.40
ph
—
6
34
140
784
2.00
10.85
4.6
10.4
0.82
0.81
mmol/l
0.12
135
749
159
932
1.94
10.80
6.0
10.4
1.57
1.24
mmol/l
0.68
133
727
121
646
2.07
10.68
2.0
1.8
—
—
—
0
0
256
1750
1.78
10.58
5.8
5.0
154.23
49.83
e6/l
0.98
185
1215
161
962
1.90
10.26
3.6
3.4
535.63
574.53
mosm/kgh2o
1.13
139
836
159
949
1.90
10.15
6.8
11.0
1.23
1.28
mmol/l
1.07
153
902
139
800
1.94
9.87
14.6
9.9
—
—
—
0
0
85
408
2.24
9.79
4.5
7.5
58.96
58.58
ng/l
0.02
78
391
79
1476
0.46
9.55
3.0
2.4
—
—
—
0
0
155
939
1.86
9.36
6.1
10.4
5.91
5.74
kpa
1.26
149
923
145
867
1.87
9.10
8.2
12.0
—
—
—
0
0
146
880
1.85
8.92
5.7
10.4
5.45
5.21
kpa
0.39
141
866
195
1286
1.74
8.79
2.9
3.2
2.37
2.38
mmol/l
0.36
180
1170
123
709
1.91
8.60
3.3
3.9
579.96
807.76
ng/l
0.39
79
488
29
86
3.47
8.35
5.0
6.4
2.41
2.33
mmol/l
0.05
22
55
205
1399
1.69
8.02
4.7
3.9
—
—
—
0
0
31
99
3.22
7.96
4.0
4.9
—
—
—
0
0
20
47
4.33
7.91
1.1
2.7
—
—
—
0
0
217
1515
1.66
7.73
4.4
4.6
38.96
34.91
u/l
0.35
210
1451
22
59
3.80
7.33
5.0
9.0
7.26
6.67
mmol/l
0.22
17
52
201
1399
1.64
7.14
4.8
4.0
0.29
0.29
e6/l
0.01
158
1055
80
424
2.01
7.09
1.6
1.6
1056.39
1246.99
nmol/l
1.17
63
325
363
2916
1.58
6.97
8.4
9.8
0.19
0.21
e9/l
2.02
319
2499
168
1125
1.67
6.90
4.0
3.3
—
—
—
0
0
354
2834
1.57
6.84
7.8
8.8
0.04
0.04
e9/l
0.15
307
2380
353
2840
1.56
6.55
7.7
8.8
0.62
0.58
e9/l
1.70
306
2386
175
1198
1.63
6.55
1.9
1.8
93.95
98.57
pmol/l
0.66
95
615
359
2921
1.54
6.16
7.7
8.8
2.36
2.24
e9/l
0.84
319
2526
5
269
0.18
6.05
1.2
1.1
—
—
—
0
0
12
14
8.66
6.05
1.0
1.4
—
—
—
0
0
93
551
1.80
5.86
1.6
1.6
459.47
457.11
pmol/l
0.02
73
479
412
3476
1.55
5.82
4.2
3.7
14.56
14.53
pmol/l
0.09
386
3229
275
2133
1.51
5.78
4.6
3.4
0.00
0.00
estimate
0.50
56
382
24
81
3.02
5.67
2.5
2.2
1.44
2.16
mmol/l
0.92
19
60
37
157
2.43
5.67
2.0
3.2
—
—
—
0
0
376
3120
1.51
5.66
12.6
11.5
4.12
3.71
e9/l
2.10
331
2629
129
846
1.65
5.64
4.8
4.0
13.29
28.64
mg/mmol
0.33
87
562
177
1256
1.56
5.57
4.3
4.3
6.31
8.09
mmol/l
5.76
163
1133
121
784
1.66
5.53
3.9
5.0
1764.91
1201.79
ng/l
0.21
103
651
70
387
1.90
5.49
9.4
13.8
0.88
0.53
mmol/l
0.29
59
317
334
2722
1.48
5.37
7.9
9.1
2.47
3.20
%
6.72
319
2611
331
2696
1.48
5.31
8.1
9.5
—
—
—
0
0
271
2124
1.48
5.27
6.2
4.9
0.00
0.00
estimate
-0.00
55
373
335
2739
1.48
5.25
8.5
9.3
8.25
8.42
%
0.54
323
2633
327
2665
1.47
5.18
7.8
9.1
0.60
0.66
%
1.10
314
2556
84
501
1.77
5.17
5.8
12.3
105.62
104.91
mmol/l
0.36
84
501
37
164
2.32
5.17
4.8
7.3
—
—
—
0
0
537
4877
1.79
5.15
11.8
9.9
28.71
28.47
u/l
0.05
527
4744
23
81
2.89
5.07
3.4
3.6
16.66
17.11
%
0.26
14
48
19
60
3.21
5.02
2.8
2.4
12.26
17.15
umol/l
1.23
19
60
272
2149
1.46
5.00
4.5
3.4
0.00
0.01
estimate
0.50
52
348
215
1626
1.48
4.92
7.8
9.3
—
—
—
0
0
122
815
1.61
4.91
3.9
3.4
64.39
259.74
mg/l
1.01
88
563
86
528
1.72
4.78
2.4
2.5
2.44
2.44
mmol/l
0.11
76
457
320
2638
1.43
4.53
10.8
11.3
0.00
0.00
e9/l
0.06
261
2042
336
2796
1.43
4.51
8.0
8.8
51.25
51.30
%
0.02
320
2695
128
885
1.55
4.42
4.3
3.7
2.48
1.44
e6/l
0.73
70
501
340
2845
1.42
4.37
8.3
8.9
33.26
33.35
%
0.04
328
2747
462
4099
1.49
4.28
5.0
4.2
2.04
2.22
mu/l
0.27
437
3836
156
1139
1.48
4.15
3.8
2.8
31.67
35.20
ng/l
0.09
104
652
70
423
1.73
4.12
2.2
2.6
23.47
30.50
u/l
1.94
57
348
357
3033
1.41
4.09
5.5
4.1
—
—
—
0
0
144
1038
1.49
4.08
4.9
3.7
0.00
0.00
estimate
0.50
53
362
58
335
1.79
3.99
4.4
3.5
—
—
—
0
0
32
616
0.49
3.91
1.7
1.8
—
—
—
0
0
13
32
4.10
3.89
1.5
1.3
—
—
—
0
0
92
607
1.59
3.87
2.3
2.2
—
—
—
0
0
13
33
3.97
3.78
1.6
1.3
—
—
—
0
0
76
1133
0.62
3.77
1.8
1.8
—
—
—
0
0
35
174
2.06
3.75
2.1
1.6
—
—
—
0
0
58
342
1.76
3.73
6.3
5.4
0.67
0.72
%
0.03
26
144
34
168
2.07
3.70
2.6
4.6
40.19
6.28
e6/l
0.54
27
120
34
168
2.07
3.70
2.6
4.7
254.67
342.08
e6/l
0.19
27
123
119
843
1.50
3.64
3.9
3.3
—
—
—
0
0
53
307
1.78
3.63
7.9
13.5
126.89
123.91
g/l
0.40
53
295
32
157
2.08
3.56
2.7
4.8
—
—
—
0
0
14
358
0.37
3.52
1.1
1.3
0.21
2.94
u/ml
—
8
272
227
1820
1.38
3.52
4.0
3.2
6.40
6.07
ph
—
5
230
53
311
1.76
3.48
6.6
5.6
0.00
0.13
%
1.00
19
108
98
675
1.53
3.42
1.5
1.4
21.75
21.38
nmol/l
0.08
87
583
17
64
2.68
3.37
1.8
4.3
—
—
—
0
0
52
307
1.75
3.35
5.8
5.2
0.62
0.48
%
0.14
21
123
44
248
1.82
3.31
3.3
3.5
—
—
—
0
0
20
83
2.44
3.28
1.4
1.5
0.29
0.35
nmol/l
0.23
15
67
19
77
2.50
3.27
1.9
3.9
—
—
—
0
0
53
319
1.71
3.20
6.7
5.5
0.10
0.08
%
0.04
21
119
39
215
1.86
3.15
4.8
14.1
0.68
0.65
%
0.34
39
215
147
1115
1.41
3.12
2.3
3.2
3.08
2.77
mg/l
0.82
125
995
75
498
1.56
3.09
1.7
1.7
—
—
—
0
0
14
336
0.40
3.07
1.1
1.2
1.12
5.38
u/ml
—
7
264
26
126
2.10
3.01
2.1
5.8
—
—
—
0
0
0
76
0.00
2.98
0.0
1.5
—
—
—
0
0
14
330
0.41
2.95
1.1
1.2
0.27
1.15
u/ml
—
7
243
27
134
2.05
2.95
4.8
7.3
—
—
—
0
0
39
220
1.81
2.94
12.0
18.4
—
—
—
0
0
176
1388
1.36
2.94
3.0
3.1
—
—
—
0
0
22
102
2.18
2.85
3.9
8.3
—
—
—
0
0
111
1450
0.71
2.78
1.9
1.9
—
—
—
0
0
5
6
8.33
2.74
1.2
1.0
—
—
—
0
0
125
946
1.39
2.66
2.2
4.0
1.56
1.69
mg/l
0.14
103
717
503
4663
1.41
2.63
25.4
16.6
14.15
14.89
%
0.35
495
4612
126
960
1.38
2.58
4.7
3.3
1.02
1.02
kg/l
0.98
28
170
52
332
1.61
2.55
2.8
7.6
21.91
23.20
s
1.98
47
315
7
189
0.36
2.45
1.1
1.8
33.43
35.27
nmol/l
—
7
181
6
174
0.34
2.44
1.0
1.1
—
—
—
0
0
528
4956
1.43
2.39
20.2
12.3
26.49
22.74
mg/l
1.78
453
3600
86
631
1.41
2.20
6.4
6.0
1.64
1.51
%
0.73
75
601
14
60
2.35
2.20
6.7
13.2
105.79
105.25
mmol/l
0.19
14
48
14
60
2.35
2.20
6.7
13.2
12.21
11.33
mmol/l
0.47
14
48
20
100
2.02
2.19
2.9
4.2
—
—
—
0
0
533
5032
1.41
2.13
17.5
10.0
—
—
—
0
0
44
652
0.64
2.11
1.3
1.2
2.39
8.00
u/ml
—
8
240
8
190
0.41
2.08
1.9
1.2
—
—
—
0
0
8
191
0.41
2.08
1.9
1.2
—
—
—
0
0
27
448
0.58
2.08
1.3
1.4
—
—
—
0
0
15
69
2.19
2.02
1.3
1.4
—
—
—
0
0
226
1930
1.26
1.99
2.9
3.1
—
—
—
0
0
5
11
4.54
1.93
1.0
1.0
—
—
—
0
0
74
542
1.40
1.92
3.9
3.7
9.61
9.07
g/l
0.54
66
515
140
1132
1.30
1.91
2.6
3.1
—
—
—
0
0
37
235
1.60
1.90
4.8
1.9
—
—
—
0
0
17
85
2.01
1.88
1.3
4.7
25.29
25.72
umol/l
0.07
17
85
283
2491
1.24
1.87
3.6
3.0
—
—
—
0
0
9
34
2.65
1.85
11.7
8.6
0.65
0.57
mmol/l
—
9
34
20
108
1.87
1.80
6.6
10.2
0.95
0.87
%
0.46
20
96
6
150
0.39
1.79
3.0
4.9
6.17
12.59
umol/l
—
6
127
354
3819
0.81
1.79
4.4
3.7
1.29
1.40
mmol/l
7.19
326
3602
89
1124
0.75
1.75
1.9
2.0
—
—
—
0
0
86
657
1.35
1.74
2.8
2.9
2.48
2.47
g/l
0.06
81
631
31
474
0.63
1.74
2.6
2.5
0.67
0.69
ug/l
0.04
22
254
62
449
1.41
1.73
5.3
4.8
71.94
65.55
e9/l
0.84
40
295
0
47
0.00
1.71
0.0
8.1
—
1.90
—
0
40
0
49
0.00
1.68
0.0
1.4
—
194.46
—
0
49
50
687
0.70
1.66
1.3
1.2
8.60
29.13
iu/ml
—
10
188
6
19
3.16
1.65
1.3
1.5
165.17
143.63
nmol/l
—
6
19
21
347
0.59
1.63
1.2
1.2
—
39.72
—
0
12
13
64
2.04
1.52
1.0
1.6
—
—
—
0
0
18
100
1.81
1.51
2.0
1.9
—
—
—
0
0
39
267
1.48
1.48
5.0
4.9
—
—
—
0
0
80
621
1.32
1.48
2.9
3.0
23.46
22.23
%
0.35
67
581
38
259
1.49
1.48
1.1
1.2
—
—
—
0
0
24
147
1.65
1.46
1.3
2.0
—
—
—
0
0
17
94
1.82
1.45
1.3
1.1
—
—
—
0
0
5
16
3.12
1.43
9.8
6.8
—
7.43
—
0
5
9
39
2.31
1.42
3.8
2.4
33.56
31.64
pg
—
9
39
24
149
1.62
1.39
1.2
1.3
356.02
340.64
ug/g
0.15
16
87
25
378
0.64
1.37
2.2
2.3
—
17.32
—
0
19
34
231
1.49
1.35
13.1
17.1
23.66
24.19
mmol/l
0.41
34
226
5
17
2.94
1.35
5.0
2.7
—
—
—
0
0
0
39
0.00
1.34
0.0
2.8
—
—
—
0
0
0
39
0.00
1.34
0.0
5.5
—
—
—
0
0
31
443
0.68
1.30
1.2
1.2
—
—
—
0
0
72
898
0.77
1.30
1.9
1.6
—
—
—
0
0
28
185
1.53
1.28
2.0
2.4
—
—
—
0
0
12
62
1.94
1.26
2.3
1.5
—
—
—
0
0
9
44
2.05
1.26
1.1
1.5
—
—
—
0
0
8
36
2.22
1.24
1.6
2.2
—
—
—
0
0
11
200
0.54
1.23
1.0
1.1
—
—
—
0
0
89
722
1.26
1.20
2.8
2.9
14.20
13.57
umol/l
0.37
82
694
6
26
2.30
1.18
1.0
1.1
—
—
—
0
0
19
117
1.63
1.16
1.1
1.3
—
—
—
0
0
8
39
2.05
1.14
1.0
2.8
2.90
4.22
nmol/l
—
8
34
348
3686
0.85
1.14
4.0
3.5
1.35
1.28
mmol/l
0.97
317
3474
47
352
1.35
1.13
2.4
1.9
18.71
16.06
iu/l
0.18
33
248
46
344
1.35
1.12
3.3
2.2
4.18
5.36
e9/l
0.65
40
316
59
739
0.77
1.11
1.3
1.2
—
—
—
0
0
33
234
1.42
1.09
1.0
1.0
10.76
8.50
mu/l
1.21
33
207
5
21
2.37
1.08
1.6
1.2
20600.00
26308.85
e6/l
—
5
13
39
286
1.38
1.08
1.8
1.3
—
—
—
0
0
18
112
1.61
1.07
5.4
10.2
1.63
1.44
%
0.77
18
99
19
120
1.59
1.07
1.2
1.2
—
—
—
0
0
57
444
1.30
1.07
1.8
1.9
1.00
1.06
g/l
0.15
51
420
15
89
1.69
1.06
5.3
4.3
54.00
52.52
%
0.12
15
89
5
22
2.27
1.02
1.4
1.2
—
—
—
0
0
7
34
2.06
1.02
3.1
3.0
105.71
105.71
mmol/l
—
7
34
7
34
2.06
1.02
3.1
3.0
—
—
—
0
0
127
1094
1.19
0.98
4.3
3.0
—
—
—
0
0
7
36
1.94
0.96
3.1
2.9
4.01
3.99
mmol/l
—
7
36
6
27
2.22
0.93
3.3
3.0
—
—
—
0
0
14
85
1.65
0.93
6.3
6.3
—
—
—
0
0
6
28
2.14
0.91
1.0
1.1
—
—
—
0
0
19
126
1.51
0.89
6.6
20.2
—
—
—
0
0
7
127
0.54
0.89
1.1
1.3
0.66
25.86
u/ml
—
7
105
15
94
1.60
0.89
2.3
2.2
—
—
—
0
0
11
63
1.75
0.88
1.8
2.5
35.33
81.97
ug/min
—
6
40
6
30
2.00
0.86
2.7
3.4
18.17
13.56
mg/l
—
6
23
14
87
1.61
0.86
3.6
3.8
3.83
3.80
e9/l
0.02
14
87
36
463
0.76
0.86
2.2
2.3
11.12
12.57
nmol/l
0.48
30
423
370
3862
0.88
0.85
4.9
4.0
2.67
2.83
mmol/l
2.94
341
3630
362
3401
1.14
0.85
6.6
4.7
40.58
38.44
mmol/mol
2.37
335
3222
8
137
0.57
0.84
1.0
1.2
—
—
—
0
0
10
57
1.75
0.82
6.0
5.7
7.45
6.93
mmol/l
—
10
57
30
223
1.35
0.80
1.3
2.3
—
—
—
0
0
14
89
1.58
0.79
4.3
5.9
1.37
2.42
ug/l
1.92
14
89
14
89
1.58
0.79
1.1
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
2.0
—
—
—
0
0
0
27
0.00
0.77
0.0
1.2
—
—
—
0
0
29
378
0.75
0.77
2.7
2.1
—
—
—
0
0
371
3857
0.89
0.76
4.4
3.8
4.38
4.63
mmol/l
5.91
345
3662
6
34
1.76
0.76
1.0
1.0
—
—
—
0
0
31
398
0.76
0.75
2.2
1.9
—
—
—
0
0
74
624
1.20
0.74
2.9
6.2
4.52
7.38
umol/l
2.69
58
539
27
352
0.75
0.73
1.3
1.6
—
—
—
0
0
5
25
1.99
0.72
4.0
4.6
158.20
215.37
ug/l
—
5
25
16
108
1.48
0.72
2.5
4.7
—
—
—
0
0
9
57
1.58
0.71
1.4
4.1
23.62
20.27
ug/l
—
9
57
23
170
1.36
0.66
3.3
2.4
—
—
—
0
0
5
30
1.66
0.61
2.0
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
2.7
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
13.82
—
0
16
28
218
1.29
0.58
1.4
2.3
81.66
94.30
u/ml
—
5
22
33
404
0.80
0.58
2.5
2.1
—
—
—
0
0
6
35
1.71
0.57
8.2
2.5
—
—
—
0
0
5
89
0.55
0.56
1.2
1.1
—
—
—
0
0
33
402
0.80
0.56
2.5
2.1
—
—
—
0
0
78
874
0.87
0.53
2.9
3.9
4790.34
5175.72
umol/l
0.03
68
794
383
3667
1.10
0.53
4.7
3.5
6.06
5.73
mmol/l
3.01
353
3398
60
516
1.17
0.52
1.3
1.4
—
—
—
0
0
33
398
0.81
0.52
2.5
2.1
—
—
—
0
0
23
178
1.29
0.51
1.8
1.7
—
—
—
0
0
35
419
0.82
0.51
1.3
1.9
—
—
—
0
0
116
1050
1.12
0.49
1.7
1.8
1.44
1.40
mmol/l
0.18
102
930
81
898
0.88
0.48
2.5
3.0
491.47
96.91
ug/g
0.71
62
744
7
47
1.48
0.47
1.1
1.1
165.81
209.32
mg/l
—
7
42
7
49
1.42
0.45
1.0
2.2
—
—
—
0
0
17
218
0.77
0.45
1.1
1.1
—
9.60
—
0
6
6
91
0.65
0.42
1.0
1.4
—
—
—
0
0
5
32
1.56
0.42
1.2
1.1
—
—
—
0
0
13
171
0.75
0.41
1.5
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
155
1638
0.92
0.38
1.7
1.6
1.68
1.85
g/l
0.82
93
892
163
1714
0.92
0.36
1.5
1.6
6.82
2.53
u/ml
0.64
30
345
23
188
1.22
0.36
1.0
1.0
-2.60
-2.05
mmol/l
—
5
36
23
188
1.22
0.36
1.0
1.0
—
—
—
0
0
9
71
1.26
0.36
2.0
1.5
4017.44
9985.23
e6/l
—
9
52
573
5636
1.16
0.34
29.6
18.3
7.25
6.92
e9/l
1.73
557
5424
6
45
1.33
0.33
2.2
1.8
—
—
—
0
0
24
199
1.21
0.33
3.0
2.4
—
—
—
0
0
15
118
1.27
0.32
13.8
10.0
—
—
—
0
0
572
5629
1.15
0.31
30.2
19.1
39.51
40.26
%
1.96
532
5404
7
51
1.37
0.31
1.3
1.1
—
—
—
0
0
7
52
1.34
0.31
1.0
1.0
—
—
—
0
0
9
118
0.75
0.27
1.2
1.3
—
—
—
0
0
572
5634
1.13
0.27
29.7
18.2
4.56
4.63
e12/l
2.39
556
5421
28
319
0.87
0.27
2.7
2.1
—
—
—
0
0
24
276
0.86
0.26
7.1
2.8
—
—
—
0
0
5
71
0.70
0.26
1.4
1.6
—
—
—
0
0
571
5627
1.12
0.25
29.9
18.3
257.55
261.97
e9/l
0.74
555
5432
37
329
1.12
0.24
2.6
2.0
8.47
6.62
u/l
0.37
22
209
11
135
0.81
0.23
1.2
1.2
—
—
—
0
0
10
78
1.28
0.23
1.8
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
51.20
—
0
10
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
5
42
1.18
0.21
1.0
1.3
—
—
nmol/l
—
0
0
293
2979
0.95
0.21
4.4
3.9
49.28
40.65
u/l
1.62
275
2852
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
4.0
—
0.47
—
0
12
0
12
0.00
0.21
0.0
1.4
—
24.67
—
0
12
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
6.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
7
58
1.20
0.18
1.9
1.3
—
—
—
0
0
340
3318
1.04
0.17
3.6
4.3
10.00
8.72
mm/h
1.13
318
3104
16
138
1.16
0.16
3.2
3.9
37.34
36.43
%
0.09
16
138
8
72
1.10
0.16
5.9
3.0
—
—
—
0
0
210
2137
0.96
0.15
3.3
3.2
95.24
91.13
ug/l
0.15
194
2017
27
244
1.10
0.15
2.7
4.3
7.18
7.59
ug/l
0.03
20
182
28
255
1.09
0.13
1.3
2.1
253.23
193.66
u/ml
0.40
13
127
65
677
0.95
0.13
1.3
1.4
382.22
456.39
titre
—
9
122
15
133
1.12
0.11
1.0
1.1
—
—
—
0
0
36
380
0.94
0.11
1.1
1.3
78.93
154.64
iu/ml
—
10
133
30
280
1.07
0.09
1.4
1.5
—
—
—
0
0
6
53
1.13
0.09
1.2
1.1
—
—
—
0
0
15
135
1.11
0.08
1.7
1.2
—
—
—
0
0
6
57
1.05
0.08
1.0
1.1
—
—
—
0
0
29
271
1.07
0.08
5.4
8.0
0.28
0.29
g/l
0.06
21
206
5
61
0.81
0.08
2.2
3.9
—
88.26
—
0
17
7
63
1.10
0.08
1.0
1.0
—
—
—
0
0
7
67
1.04
0.08
1.4
1.1
—
—
—
0
0
25
264
0.94
0.07
1.2
1.1
—
—
—
0
0
37
385
0.95
0.07
1.5
1.7
—
—
—
0
0
7
81
0.86
0.07
2.3
1.6
—
—
—
0
0
9
83
1.08
0.07
11.7
28.4
11.99
12.09
%
—
9
83
9
87
1.03
0.07
1.9
2.8
—
—
—
0
0
39
403
0.96
0.06
1.6
1.5
—
—
—
0
0
84
817
1.02
0.05
3.2
3.6
1.22
1.47
ug/l
0.78
79
747
14
149
0.93
0.04
1.1
1.2
—
2.76
—
0
10
70
684
1.02
0.02
1.8
1.6
—
—
—
0
0
42
411
1.02
0.00
1.5
1.4
—
—
—
0
0
148
1475
1.00
0.00
1.5
1.5
—
—
—
0
0
52
513
1.01
0.00
1.3
1.4
68.98
290.19
u/ml
3.55
47
479
15
145
1.03
0.00
1.5
1.7
—
—
—
0
0
23
233
0.98
0.00
3.7
2.5
1312.43
2796.83
u/l
—
7
88
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
11.9
—
—
—
0
0
5
49
1.01
0.00
1.4
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
3.53
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
8
83
0.96
0.00
1.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.01
0.00
1.0
1.3
0.54
0.53
nmol/l
—
5
44
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
8.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
124.40
—
0
5
0
5
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
346.29
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
9.58
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.6
—
—
—
0
0
5
58
0.85
-0.00
1.8
1.0
—
—
—
0
0
6
59
1.01
-0.00
51.2
48.7
6.43
6.59
ug/l
—
6
53
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
27.74
—
0
7

Mortality – FinRegistry

Association

Association between endpoint F5_OTHRET and mortality.

Females

Parameter HR [95% CI] p-value
F5_OTHRET 5.514 [4.46, 6.81] < 0.001
Birth year 0.994 [0.98, 1.0] 0.157

During the follow-up period (1.1.1998 — 31.12.2019), 447 out of 3621 females with F5_OTHRET died.

Males

Parameter HR [95% CI] p-value
F5_OTHRET 4.418 [3.68, 5.31] < 0.001
Birth year 0.984 [0.97, 0.99] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 509 out of 5439 males with F5_OTHRET died.

Mortality risk

Mortality risk for people of age

years, who have F5_OTHRET.

N-year risk Females Males
1 0.518% 1.017%
5 2.797% 5.521%
10 7.457% 12.32%
15 14.119% 20.931%
20 23.79% 32.784%

Relationships between endpoints

Index endpoint: F5_OTHRET – Other and unspecified mental retardation

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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