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Central retinal artery occlusion

DOID EFO Endpoint Browser PheWeb

H7_CENTRRETARTOCC

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H34.1
  • Hospital discharge: ICD-9 — 3623A
  • Hospital discharge: ICD-8 — 37702
  • Cause of death: ICD-10 — H34.1
  • Cause of death: ICD-9 — 3623A
  • Cause of death: ICD-8 — 37702

2 out of 7 registries used, show all original rules.

827

4. Check minimum number of events

None

827

5. Include endpoints

None

827

6. Filter based on genotype QC (FinnGen only)

797

Control definitions (FinnGen only)

Control exclude
H7_CHOROIDRETINA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H34
Name in latin
Occlusio arteriae centralis retinae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6473 2574 3815
Only index persons 5023 2088 2935
Unadjusted period prevalence (%)
Whole population 0.09 0.07 0.11
Only index persons 0.10 0.08 0.11
Median age at first event (years)
Whole population 72.13 75.00 70.25
Only index persons 72.80 75.34 71.00

-FinnGen-

Key figures

All Female Male
Number of individuals 797 274 523
Unadjusted period prevalence (%) 0.19 0.10 0.24
Median age at first event (years) 70.96 70.94 70.97

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
827
Matched controls
8270
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
307.7
778
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
9.9
145.6
190
242
H34.8
ICD-10 Finland
Other retinal vascular occlusions
781.2
138.0
132
*
CKC12
NOMESCO Finland
Photocoagulation of retina
204.8
135.1
137
8
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
472.0
125.4
122
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
1318.7
119.9
114
*
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
47.0
116.7
69
16
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
11.9
115.3
125
122
H43.1
ICD-10 Finland
Vitreous haemorrhage
24.5
110.5
80
36
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
11.0
109.1
125
132
XCW99
NOMESCO Finland
Other investigative procedure of eye
7.2
104.8
179
306
B01AC04
ATC
clopidogrel; oral
4.0
78.5
339
1235
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
11.7
75.1
80
75
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
7.8
73.3
109
158
XCK10
NOMESCO Finland
Photography of fundus of eye
5.2
69.8
165
377
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
16.1
68.9
60
40
G45.3
ICD-10 Finland
Amaurosis fugax
11.9
66.7
70
64
H53.9
ICD-10 Finland
Visual disturbance, unspecified
9.6
65.4
80
91
AA1AD
NOMESCO Finland
CT of head and brain
3.3
63.1
403
1834
XCK00
NOMESCO Finland
Perimetry
5.4
55.9
120
250
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
149.9
53.5
56
*
H53.1
ICD-10 Finland
Subjective visual disturbances
5.6
50.0
103
206
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
5.1
49.9
115
254
S01ED51
ATC
timolol, combinations; ophthalmic
4.4
49.8
144
382
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.2
49.7
154
430
XCH00
NOMESCO Finland
Eye pressure measurement
6.1
46.1
85
153
WX140
NOMESCO Finland
Parabulbar anesthesy
8.3
45.6
62
80
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
43.5
201
730
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
15.3
42.7
38
26
C10AA05
ATC
atorvastatin; oral
2.6
39.7
483
2886
PA6AD
NOMESCO Finland
CT of neck arteries
6.7
38.6
64
103
XCD20
NOMESCO Finland
Photoangiography of eye
53.8
34.7
41
8
S01EC01
ATC
acetazolamide; systemic
7.4
33.8
50
71
3623A
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO ARTERIAE CENTRALIS RETINAE]
+∞
33.6
32
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.9
31.4
177
709
H53.4
ICD-10 Finland
Visual field defects
7.0
29.6
46
69
CS494
NOMESCO Finland
Other visual field testing
6.6
28.1
46
73
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.7
26.9
180
783
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.6
26.9
182
797
H54.4
ICD-10 Finland
Blindness, monocular
74.8
25.9
29
*
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
45.9
25.7
31
7
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.6
25.0
61
140
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
9.4
24.9
30
33
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
5.9
24.5
45
80
C10AA01
ATC
simvastatin; oral
2.1
23.2
491
3398
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.9
23.2
52
111
H3600, E113,
ICD-10 Finland
+∞
23.0
22
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.1
22.2
322
1932
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
22.1
213
1087
H33.0
ICD-10 Finland
Retinal detachment with retinal break
+∞
22.0
21
*
37702
ICD-8 Finland
Other diseases of retina and optic nerve, Embolia, spasmus arteriae centralis retinae
+∞
22.0
21
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
21.9
354
2206
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
5.9
21.8
40
71
CKC20
NOMESCO Finland
Cryopexy of undetached retina
+∞
20.9
20
*
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.8
20.6
65
181
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
21.4
20.0
29
14
I10
ICD-10 Finland
Essential (primary) hypertension
2.1
19.8
606
4673
CKC10
NOMESCO Finland
Local photocoagulation of retina
75.4
19.8
22
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.7
19.7
118
482
H33.3
ICD-10 Finland
Retinal breaks without detachment
204.7
19.6
20
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
25.3
19.6
27
11
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
19.2
230
1272
C03CA01
ATC
furosemide; systemic
1.9
19.1
406
2745
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
19.0
453
3182
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.7
19.0
111
447
H3603, E113,
ICD-10 Finland
+∞
18.8
18
*
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.5
18.8
137
614
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.1
18.7
85
298
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
2.7
18.5
108
434
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.5
18.3
135
608
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.5
18.3
126
550
S01EA05
ATC
brimonidine; ophthalmic
4.5
18.2
45
104
C08CA01
ATC
amlodipine; oral
1.9
17.9
401
2740
H3603, E103,
ICD-10 Finland
+∞
17.8
17
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.9
17.7
373
2498
S01EE01
ATC
latanoprost; ophthalmic
2.9
17.6
90
337
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.0
17.4
274
1662
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.0
17.3
271
1640
114
Kela drug reimbursment
Glaucoma
2.5
17.2
118
513
H26.4
ICD-10 Finland
After-cataract
2.5
17.0
117
510
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.3
16.0
131
616
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
14.9
15.9
26
18
AN1
HP
Coronary angiography
2.2
15.8
161
829
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
4.1
15.7
44
112
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
+∞
15.7
15
*
H3601, E113,
ICD-10 Finland
+∞
15.7
15
*
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
15.7
15
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
14.1
15.6
26
19
S01EC54
ATC
brinzolamide, combinations; ophthalmic
6.4
15.5
26
42
A10AA01, ,
ATC
6.6
15.4
25
39
H25.1
ICD-10 Finland
Senile nuclear cataract
1.8
15.2
325
2157
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
2.8
15.2
79
298
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
14.9
231
1383
H54.6
ICD-10 Finland
Moderate visual impairment, monocular
57.8
14.8
17
*
F05
ICPC
Visual disturbance other
4.3
14.8
39
95
H34.0
ICD-10 Finland
Transient retinal artery occlusion
+∞
14.6
14
*
B01AC07
ATC
dipyridamole; systemic
2.6
14.5
89
366
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.7
14.5
79
306
C10AX09
ATC
ezetimibe; oral
2.1
14.5
154
805
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.3
14.1
53
166
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.9
14.0
227
1375
C09AA05
ATC
ramipril; oral
1.8
13.6
283
1850
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.4
13.6
96
422
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
+∞
13.6
13
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
142.2
13.5
14
*
C07AB07
ATC
bisoprolol; oral
1.8
13.5
493
3783
A10AB05
ATC
insulin aspart; parenteral
2.7
13.3
75
295
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
13.3
303
2032
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.0
13.2
155
838
205
Kela drug reimbursment
Chronic hypertension
1.8
13.0
323
2216
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
17.1
13.0
20
12
I50.0
ICD-10 Finland
Congestive heart failure
2.2
13.0
121
599
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
4.2
12.9
35
87
B01AA03
ATC
warfarin; systemic
1.8
12.7
266
1737
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
71.0
12.6
14
*
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
12.5
12
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
131.9
12.5
13
*
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.8
12.4
234
1479
C08CA13
ATC
lercanidipine; oral
2.0
12.3
151
828
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
12.3
93
421
S01ED01
ATC
timolol; ophthalmic
3.2
12.3
50
164
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.5
12.2
80
339
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.7
12.0
64
245
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
11.9
202
1235
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.3
11.8
30
71
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.4
11.8
87
390
CKC15
NOMESCO Finland
Panretinal photocoagulation
30.5
11.7
15
5
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
65.9
11.6
13
*
PAW37
NOMESCO Finland
Biopsy of temporal artery
11.3
11.6
21
19
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.5
11.5
28
64
H3600, E103,
ICD-10 Finland
+∞
11.5
11
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
121.6
11.5
12
*
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
121.6
11.5
12
*
H35.37
ICD-10 Finland
Macular holes
121.6
11.5
12
*
A10AA02, ,
ATC
3.9
11.4
34
91
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
12.0
11.4
20
17
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
11.3
265
1777
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.4
11.1
28
66
C01DA14
ATC
isosorbide mononitrate; oral
1.8
11.0
227
1466
L28
ICPC
Limited function/disability (L)
1.8
10.9
191
1174
ZXA05
NOMESCO Finland
Left side
1.7
10.8
230
1496
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
3.3
10.8
40
124
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
4.4
10.6
26
60
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
10.5
146
835
CKD40
NOMESCO Finland
Endophotocoagulation of retina
111.4
10.4
11
*
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
111.4
10.4
11
*
H54.5
ICD-10 Finland
Severe visual impairment, monocular
16.3
10.4
16
10
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
33.0
10.3
13
*
S01EA03
ATC
apraclonidine; ophthalmic
10.8
10.3
19
18
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
10.3
130
719
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
4.2
10.2
27
66
T90
ICPC
Diabetes non-insulin dependent
1.7
10.2
220
1434
ZXD05
NOMESCO Finland
Urgent procedure
1.7
10.2
259
1766
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.0
10.2
22
28
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
4.5
10.1
24
54
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
2.9
10.0
47
168
H25.0
ICD-10 Finland
Senile incipient cataract
2.5
10.0
66
281
H54.1
ICD-10 Finland
Severe visual impairment, binocular
55.7
9.7
11
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
5.1
9.6
20
40
A10AE04
ATC
insulin glargine; parenteral
2.2
9.6
88
432
H40.0
ICD-10 Finland
Glaucoma suspect
2.3
9.6
73
332
A10AE05
ATC
insulin detemir; parenteral
2.7
9.5
51
196
M04AA01
ATC
allopurinol; systemic
1.8
9.5
168
1033
A10AB01
ATC
insulin (human); parenteral
4.0
9.5
27
70
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
9.4
9
*
H3601, E103,
ICD-10 Finland
+∞
9.4
9
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.4
9.4
67
296
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.3
9.4
73
335
280
Kela drug reimbursment
Clopidogrel
3.5
9.3
32
95
N02BE01
ATC
paracetamol; systemic, rectal
1.8
9.2
698
6171
I20.09
ICD-10 Finland
Unstable angina
2.2
9.2
79
377
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
2.8
9.1
46
171
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.1
9.1
25
63
AA1
HP
Conventional CABG
3.2
9.0
36
117
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
37.1
9.0
11
*
I25.2
ICD-10 Finland
Old myocardial infarction
2.0
9.0
102
542
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
8.9
329
2440
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.6
8.9
29
83
C03DA01
ATC
spironolactone; oral
1.8
8.8
135
793
H57.1
ICD-10 Finland
Ocular pain
3.7
8.8
27
74
C07AB02
ATC
metoprolol; systemic
1.7
8.7
221
1496
F01
ICPC
Eye pain
4.0
8.6
24
61
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
91.0
8.4
9
*
A10AC01
ATC
insulin (human); parenteral
2.2
8.4
70
330
PD5BD
NOMESCO Finland
Extensive CT of aorta
3.4
8.4
30
91
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
8.4
57
246
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
4.5
8.4
20
45
H47.2
ICD-10 Finland
Optic atrophy
12.9
8.4
14
11
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
8.4
289
2104
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.3
8.3
31
97
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
8.2
249
1756
S01EC04
ATC
brinzolamide; ophthalmic
2.6
8.2
47
187
R4120
NOMESCO Finland
Occupational therapy
2.3
8.2
59
262
A46
ICD-10 Finland
Erysipelas
1.8
8.1
146
899
M48.0
ICD-10 Finland
Spinal stenosis
1.8
8.1
129
766
C02AC05
ATC
moxonidine; oral
2.4
8.0
56
245
A02BC02
ATC
pantoprazole; systemic
1.5
8.0
526
4393
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
7.3
8.0
18
25
81
HP
Angiography of the heart and coronary arteries
2.0
8.0
92
492
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
7.9
79
400
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
7.9
250
1778
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
7.9
218
1501
H02AB06
ATC
prednisolone; systemic
1.5
7.9
381
2975
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
7.9
276
2009
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
1.9
7.9
110
626
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
4.7
7.9
18
39
J01DB01
ATC
cefalexin; oral
1.6
7.8
612
5299
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
7.8
238
1680
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.6
7.7
25
71
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.7
195
1315
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
8.1
7.6
16
20
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
6.8
7.6
18
27
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.0
7.6
80
414
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.4
7.6
27
82
PE1YT
NOMESCO Finland
Femoral or popliteal artery PTA with stent
4.5
7.5
18
41
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
80.8
7.4
8
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.4
284
2108
XCW10
NOMESCO Finland
Assessment of vision
6.9
7.3
17
25
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
3.6
7.3
24
69
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
4.2
7.3
19
46
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
7.2
233
1660
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
15.9
7.2
11
7
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
7.2
278
2061
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
3.3
7.2
26
80
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
8.0
7.1
15
19
ZX198
NOMESCO Finland
Other local administration
12.2
7.1
12
10
A10BK03
ATC
empagliflozin; oral
2.0
7.1
81
432
S18
ICPC
Laceration/cut
1.5
7.0
357
2797
S01EE04
ATC
travoprost; ophthalmic
3.3
7.0
26
81
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.7
7.0
37
142
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
2.8
6.9
34
125
S01EE03
ATC
bimatoprost; ophthalmic
3.0
6.9
29
98
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.0
6.9
79
422
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.2
6.8
59
283
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
9.4
6.8
13
14
PE1AT
NOMESCO Finland
Femoral artery PTA
3.7
6.8
21
58
H36.01
ICD-10 Finland
Diabetic maculopathy
40.4
6.8
8
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
40.4
6.8
8
*
H33.5
ICD-10 Finland
Other retinal detachments
16.9
6.8
10
6
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.4
6.7
44
187
A10BH05
ATC
linagliptin; oral
2.2
6.7
58
278
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
6.6
151
988
WX199
NOMESCO Finland
Other local analgesia
2.6
6.6
36
140
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.7
6.6
131
827
K29
ICPC
Cardiovascular sympt/complt other
2.4
6.6
46
202
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.5
250
1844
ZXA00
NOMESCO Finland
Right side
1.5
6.5
226
1634
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
70.4
6.4
7
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
70.4
6.4
7
*
B03XA02
ATC
darbepoetin alfa; parenteral
3.0
6.4
27
91
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
6.4
27
91
XF600
NOMESCO Finland
Bloodpressure measurement
2.1
6.4
59
290
C08CA05
ATC
nifedipine; systemic
2.0
6.4
72
381
A10BA02
ATC
metformin; oral
1.5
6.4
255
1894
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
6.4
114
699
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
6.4
96
560
K90
ICPC
Stroke/cerebrovascular accident
2.5
6.4
39
161
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
6.4
63
319
S01EC03
ATC
dorzolamide; ophthalmic
3.5
6.3
21
61
ZXA10
NOMESCO Finland
Bilateral
1.6
6.3
155
1033
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
3.3
6.3
23
71
S97
ICPC
Chronic ulcer skin
2.0
6.3
64
327
SPAT1263
SPAT
Sampling
1.5
6.3
313
2430
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
18.2
6.3
9
5
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
+∞
6.3
6
*
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
6.3
6
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
6.3
6
*
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
4.0
6.2
17
43
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.2
459
3836
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
6.1
158
1066
K78
ICPC
Atrial fibrillation/flutter
1.8
6.1
98
583
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
12.6
6.1
10
8
F28
ICPC
Limited function/disability (F)
8.7
6.1
12
14
NHQ40
NOMESCO Finland
Amputation of toe
3.2
6.1
23
73
J01FF01
ATC
clindamycin; systemic
1.5
6.0
202
1444
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
6.0
75
412
N03AX16
ATC
[U] pregabalin
1.6
6.0
174
1205
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.0
6.0
65
340
I50.1
ICD-10 Finland
Left ventricular failure
2.0
6.0
65
340

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
414
2076
2.99
52.17
2.5
2.2
146.92
266.56
u/l
2.17
399
1943
271
1149
3.02
45.10
2.1
1.9
30.72
30.11
s
0.73
265
1110
527
3532
2.36
30.16
27.6
19.8
1.37
1.40
inr
0.25
150
998
566
3972
2.35
28.18
7.5
5.0
6.96
6.82
mmol/l
0.97
552
3741
154
702
2.47
20.49
2.5
2.7
4.41
6.58
ug/l
1.65
135
601
406
2806
1.88
17.33
6.2
4.2
52.43
61.26
ng/l
0.23
351
2170
359
2392
1.89
17.13
4.0
3.2
2855.11
1983.89
ng/l
1.72
333
2068
581
4524
1.96
16.93
4.8
4.1
16.66
14.60
mm/h
2.09
542
4107
64
202
3.35
16.76
1.9
2.0
20.91
22.07
s
0.76
53
188
182
966
2.13
16.62
9.2
5.4
1.09
1.02
mmol/l
2.15
171
881
326
2129
1.88
16.37
3.2
2.6
—
—
—
0
0
467
3432
1.83
15.83
10.6
7.0
1.20
1.21
mmol/l
2.47
401
2896
418
2976
1.82
15.68
6.3
5.2
0.64
0.62
e9/l
0.57
367
2542
418
2985
1.81
15.44
6.3
5.3
0.04
0.04
e9/l
0.44
366
2558
427
3078
1.80
15.20
6.7
5.4
0.21
0.20
e9/l
0.55
373
2686
473
3529
1.80
14.85
9.1
8.6
4.60
4.32
e9/l
1.63
425
3068
421
3037
1.79
14.81
6.4
5.3
1.61
1.82
e9/l
3.70
374
2665
414
2977
1.78
14.68
3.3
2.8
—
—
—
0
0
462
3445
1.77
14.32
6.2
6.3
12.23
12.32
umol/l
0.05
444
3266
139
704
2.17
14.14
11.7
6.5
13.51
11.26
mmol/l
2.82
133
665
431
3161
1.76
14.06
10.2
6.2
1.20
1.21
mmol/l
1.49
405
2852
416
3024
1.76
13.97
5.1
4.9
34.23
34.51
g/l
0.44
381
2788
253
1614
1.82
13.11
3.0
2.5
—
—
—
0
0
301
2024
1.77
13.04
4.0
3.2
440.94
274.61
mg/l
0.26
220
1349
386
2795
1.71
12.76
7.1
5.8
—
—
—
0
0
394
2870
1.71
12.73
6.8
5.7
23.55
25.82
%
3.94
375
2675
388
2815
1.71
12.72
6.3
5.4
60.60
58.60
%
2.55
368
2623
380
2744
1.71
12.65
6.6
5.4
0.70
0.62
%
2.16
360
2549
183
1070
1.91
12.41
3.8
2.5
2.22
2.23
g/l
0.08
176
974
386
2811
1.70
12.37
6.7
5.5
3.05
2.85
%
0.60
365
2614
387
2825
1.70
12.26
6.9
5.8
9.38
8.94
%
1.66
368
2625
137
728
2.06
12.20
5.4
3.5
1.62
2.15
mmol/l
1.02
109
599
189
1124
1.88
12.14
3.4
3.1
0.83
0.81
mmol/l
0.81
181
1038
175
1019
1.91
11.98
3.9
2.6
17.93
22.40
%
5.84
152
861
121
625
2.10
11.60
10.8
8.6
—
—
—
0
0
162
933
1.92
11.42
3.0
2.4
1.95
1.77
%
1.30
145
822
88
403
2.32
11.34
1.8
1.8
1.57
1.50
g/l
0.24
78
350
275
1867
1.71
11.15
2.9
2.2
3.23
3.13
mg/l
0.27
240
1569
296
2050
1.69
11.15
3.8
3.1
6.48
7.43
mmol/l
4.31
251
1689
308
2164
1.67
10.94
4.5
3.7
13.35
9.22
mg/mmol
0.62
224
1404
189
1158
1.82
10.93
3.9
2.6
9.76
12.17
umol/l
6.77
180
1068
106
535
2.13
10.77
3.0
2.5
—
—
—
0
0
314
2226
1.66
10.72
5.2
4.4
—
—
—
0
0
287
2003
1.66
10.33
3.5
2.5
57.53
99.26
u/l
0.52
272
1828
532
4325
1.64
10.32
5.9
5.0
133.62
2655.95
e6/l
1.40
13
79
125
684
1.97
10.18
3.5
2.4
73.72
66.22
e9/l
1.46
97
532
156
923
1.85
10.02
8.3
7.4
0.41
1.32
mmol/l
1.74
118
713
19
36
5.38
9.67
3.9
12.5
—
—
—
0
0
154
921
1.83
9.53
8.5
7.4
5.04
5.07
kpa
0.15
147
870
154
922
1.82
9.49
8.5
7.4
12.57
11.71
kpa
0.96
147
872
580
4869
1.64
9.42
9.5
7.7
85.39
80.73
u/l
1.26
550
4524
25
62
4.13
9.30
1.2
1.3
4.80
7.68
u/ml
—
10
25
134
774
1.87
9.25
2.1
1.8
—
—
—
0
0
215
1427
1.68
9.21
4.6
3.9
—
—
—
0
0
533
4404
1.59
9.05
5.4
4.5
—
—
—
0
0
63
276
2.39
8.98
1.3
1.4
—
7.84
—
0
5
333
2476
1.58
8.95
4.3
2.8
156.37
157.69
ug/l
0.04
311
2222
680
5985
1.77
8.88
27.9
17.8
27.23
28.55
mg/l
0.47
616
4930
195
1273
1.70
8.84
1.9
1.6
1.47
1.47
mg/l
0.00
162
1010
116
653
1.90
8.64
3.4
2.8
67.22
65.75
g/l
1.23
102
589
60
263
2.38
8.54
4.2
3.4
57.67
83.34
mg/l
0.49
47
211
381
2945
1.54
8.48
2.4
2.1
90.37
91.92
pmol/l
0.25
211
1525
59
258
2.39
8.45
4.3
3.3
2.83
1.26
ratio
—
6
23
60
265
2.36
8.40
4.2
3.4
50.87
84.53
mg/l
0.32
46
214
281
2051
1.56
7.98
7.3
4.1
7.40
7.40
ph
0.10
51
389
223
1562
1.59
7.50
1.9
1.8
1158.39
1155.97
nmol/l
0.01
176
1163
317
2407
1.51
7.38
4.4
3.7
5.33
5.86
ph
—
6
116
321
2455
1.50
7.17
5.0
4.1
69.99
140.29
e6/l
1.04
241
1845
45
188
2.47
7.14
4.6
3.4
—
—
—
0
0
21
56
3.82
7.11
1.1
1.3
—
—
—
0
0
242
1746
1.55
7.09
3.7
2.9
2412.40
8991.82
umol/l
2.03
211
1465
383
3043
1.48
7.05
4.8
4.0
0.00
0.00
estimate
-0.00
60
565
381
3028
1.48
6.98
4.7
4.0
0.00
0.00
estimate
0.50
67
628
430
3504
1.47
6.91
3.6
3.2
55.33
55.03
u/l
0.02
401
3187
203
1419
1.57
6.81
5.8
4.2
277.26
326.98
ng/l
0.15
177
1230
88
495
1.87
6.56
4.0
3.1
123.93
125.57
g/l
0.25
88
481
695
6303
1.64
6.35
33.5
21.3
139.09
139.60
mmol/l
4.32
683
6111
696
6315
1.64
6.34
33.7
21.4
4.03
4.02
mmol/l
0.64
681
6118
245
1809
1.50
6.33
1.7
1.6
17.81
19.93
nmol/l
1.53
211
1520
252
1873
1.50
6.30
3.0
3.3
28.66
35.89
u/l
3.56
241
1774
94
547
1.81
6.29
4.7
4.0
112.14
99.62
ng/l
0.55
81
474
374
3008
1.44
6.21
6.0
5.3
0.00
0.00
estimate
-0.00
63
576
503
4284
1.44
6.06
3.8
3.7
15.30
15.07
pmol/l
1.14
459
3791
616
5457
1.50
6.04
5.0
4.1
1.29
1.26
mmol/l
0.61
578
4835
285
2192
1.46
5.93
4.2
3.6
305.65
107.18
e6/l
0.49
229
1740
605
5365
1.48
5.68
5.0
4.5
2.29
2.07
mu/l
0.80
556
4776
296
2308
1.44
5.67
3.1
3.4
2.36
2.35
mmol/l
0.36
256
1986
214
1571
1.49
5.59
3.1
2.8
4.04
4.35
e6/l
0.25
191
1413
627
5609
1.49
5.54
8.6
6.3
42.82
40.68
mmol/mol
5.75
586
5080
210
1539
1.49
5.53
8.1
6.6
—
—
—
0
0
65
351
1.92
5.50
1.8
1.8
2.81
1.75
ug/l
0.40
58
295
284
2213
1.43
5.41
3.5
3.4
—
—
—
0
0
633
5688
1.48
5.34
5.5
4.6
3.96
4.40
mmol/l
21.76
605
5142
21
69
3.10
5.25
2.4
2.5
—
—
—
0
0
510
4418
1.40
5.17
5.2
4.4
—
—
—
0
0
188
1364
1.49
5.17
5.3
4.5
1.02
1.02
kg/l
0.07
30
215
58
308
1.95
5.16
5.9
4.1
—
—
—
0
0
626
5635
1.46
5.03
5.5
4.6
1.31
1.42
mmol/l
8.64
591
5042
701
6459
1.56
5.00
38.9
25.8
7.19
6.96
e9/l
2.14
678
6216
113
739
1.61
4.94
3.2
3.1
266.23
253.20
ng/l
0.13
107
682
700
6454
1.55
4.91
39.4
26.0
38.47
39.37
%
2.62
658
5895
700
6454
1.55
4.91
38.8
25.8
232.59
236.21
e9/l
0.73
684
6242
680
6232
1.51
4.90
14.1
11.0
24.27
24.76
u/l
0.36
660
5942
700
6456
1.55
4.88
38.8
25.7
92.02
91.90
fl
0.27
688
6309
700
6456
1.55
4.88
38.7
25.7
30.43
30.51
pg
0.46
688
6308
700
6457
1.55
4.87
39.2
26.0
129.52
132.74
g/l
5.42
690
6309
700
6457
1.55
4.87
38.9
25.8
4.31
4.38
e12/l
3.06
678
6218
122
833
1.54
4.43
1.2
1.2
—
—
—
0
0
144
1021
1.50
4.39
2.3
2.1
—
—
—
0
0
261
2071
1.38
4.29
5.4
4.4
—
—
—
0
0
532
4714
1.36
4.25
35.0
23.6
329.80
331.60
g/l
4.09
523
4666
641
5856
1.42
4.24
6.2
5.3
2.18
2.55
mmol/l
23.09
609
5252
47
251
1.93
4.16
3.0
2.3
37.28
37.15
g/l
0.05
38
218
88
565
1.62
4.15
4.5
4.5
—
—
—
0
0
52
288
1.86
4.12
2.8
2.4
10.59
10.76
g/l
0.09
43
254
69
417
1.71
4.10
10.1
10.5
—
—
—
0
0
54
304
1.83
4.07
1.3
1.2
—
—
—
0
0
108
738
1.53
3.91
2.5
2.7
10.82
9.18
umol/l
0.22
94
648
95
634
1.56
3.83
1.2
1.3
1227.69
438.55
titre
1.47
26
138
298
2454
1.34
3.76
2.5
2.1
78.45
78.79
nmol/l
0.08
263
2116
76
483
1.63
3.75
4.9
3.9
7.43
7.39
ph
—
6
54
320
2665
1.33
3.73
13.1
10.2
0.00
0.00
e9/l
0.12
259
2157
58
345
1.73
3.66
9.3
3.7
23.81
24.32
mmol/l
0.47
58
333
656
6085
1.38
3.42
25.0
17.1
—
—
—
0
0
58
355
1.68
3.33
4.8
4.1
—
—
—
0
0
92
631
1.52
3.29
1.4
1.3
—
—
—
0
0
129
947
1.43
3.28
1.6
1.5
2.86
2.72
g/l
0.22
71
529
88
599
1.52
3.26
4.3
3.4
—
—
—
0
0
234
1896
1.33
3.22
4.0
3.5
—
—
—
0
0
245
1999
1.32
3.21
4.1
3.5
0.58
0.51
e6/l
0.18
191
1562
24
110
2.22
3.21
1.3
1.6
—
—
—
0
0
76
503
1.56
3.20
2.1
1.5
—
—
—
0
0
17
67
2.57
3.14
2.4
2.7
1.20
2.48
g/24h
0.55
11
32
57
355
1.65
3.08
1.1
1.2
—
—
—
0
0
26
126
2.10
3.05
1.7
1.3
75.19
61.29
mmol/l
0.76
21
101
86
592
1.51
3.04
1.9
1.5
—
—
—
0
0
210
1689
1.33
3.03
5.3
4.3
0.00
0.00
estimate
-0.00
57
543
77
521
1.53
2.95
2.2
2.0
370.84
383.55
nmol/l
0.25
70
464
178
1404
1.34
2.92
2.6
3.2
2.48
2.46
mmol/l
0.70
152
1213
54
343
1.61
2.72
2.7
1.8
2.06
1.62
g/l
0.26
49
306
95
685
1.44
2.67
6.1
4.5
—
—
—
0
0
623
5806
1.30
2.64
5.9
5.0
6.26
6.08
mmol/l
2.45
574
5166
11
36
3.08
2.57
1.2
1.6
—
—
—
0
0
8
213
0.37
2.56
1.1
1.2
—
—
—
0
0
36
209
1.76
2.54
3.6
3.0
24.68
24.77
mmol/l
0.04
36
202
155
1228
1.32
2.46
3.6
3.0
1.48
1.32
e6/l
0.12
95
737
9
27
3.36
2.39
4.7
2.9
—
—
—
0
0
17
77
2.23
2.39
1.2
1.1
—
—
—
0
0
72
507
1.46
2.32
4.4
3.9
1.67
0.84
%
0.99
24
203
104
783
1.38
2.31
2.9
4.1
5.30
17.40
ug/l
1.24
89
670
82
594
1.42
2.27
3.2
2.3
46.56
33.04
u/l
1.00
72
504
35
209
1.70
2.27
22.5
12.0
—
—
—
0
0
65
451
1.48
2.26
4.4
4.0
0.15
0.70
%
0.46
20
151
30
172
1.77
2.23
2.7
2.3
95.70
86.77
ug/min
0.08
20
104
63
438
1.47
2.17
2.8
2.7
10.91
10.93
g/l
0.01
57
387
46
301
1.56
2.10
1.5
1.4
—
—
—
0
0
9
207
0.43
2.10
1.2
1.5
—
—
—
0
0
32
191
1.70
2.09
2.4
3.2
1.53
1.62
mmol/l
0.36
32
186
130
1029
1.31
2.08
1.3
1.2
1.93
1.41
u/ml
0.26
25
250
45
294
1.56
2.07
5.9
4.5
24.51
25.16
mmol/l
0.81
39
267
6
15
4.02
2.04
1.5
1.8
—
—
—
0
0
34
208
1.66
2.04
4.9
3.6
—
—
—
0
0
10
38
2.65
2.01
1.0
1.2
192.50
137.46
nmol/l
—
10
38
66
473
1.43
1.97
4.5
4.0
0.05
0.13
%
0.72
20
169
29
172
1.71
1.95
4.8
2.6
—
—
—
0
0
273
2379
1.22
1.93
2.3
2.3
—
—
—
0
0
13
58
2.26
1.91
1.1
1.4
—
—
—
0
0
66
476
1.42
1.91
2.3
1.5
—
—
—
0
0
7
22
3.20
1.88
1.4
1.9
1894.14
776.18
u/ml
—
7
22
63
453
1.42
1.86
4.4
3.7
1.64
0.69
%
0.85
22
173
144
1174
1.27
1.85
4.0
3.2
2.18
1.83
e6/l
0.24
87
688
28
168
1.69
1.82
1.9
2.9
34.86
35.25
umol/l
0.03
28
148
12
53
2.28
1.81
1.3
1.2
—
—
—
0
0
30
185
1.65
1.77
3.1
2.8
7.55
7.74
kpa
0.29
30
179
13
61
2.15
1.72
1.4
1.4
—
—
nmol/l
—
0
0
28
172
1.65
1.69
1.6
1.5
—
—
—
0
0
10
40
2.52
1.67
1.2
1.1
—
—
—
0
0
10
41
2.46
1.64
2.4
2.2
—
—
—
0
0
28
174
1.63
1.62
1.5
1.1
—
—
—
0
0
28
176
1.61
1.56
1.4
1.6
243.07
264.63
ug/g
0.22
14
109
5
15
3.35
1.52
1.0
1.2
—
—
—
0
0
20
116
1.74
1.50
3.6
1.4
1.03
0.85
nmol/l
0.59
15
95
528
4963
1.18
1.46
30.9
21.1
15.39
15.41
%
0.03
522
4862
5
16
3.14
1.44
32.2
7.2
—
—
—
0
0
6
22
2.74
1.43
1.0
1.1
—
—
—
0
0
180
1551
1.21
1.40
1.9
1.8
69536811.79
432.50
pmol/l
0.50
151
1258
176
1515
1.21
1.38
3.6
3.2
506.12
558.39
mosm/kgh2o
3.06
153
1289
16
89
1.81
1.38
1.4
1.1
—
—
—
0
0
6
23
2.62
1.37
1.3
2.2
—
—
—
0
0
14
75
1.88
1.35
3.1
2.4
—
—
—
0
0
172
1482
1.20
1.34
1.4
1.3
—
—
—
0
0
12
61
1.98
1.33
2.9
3.6
12.80
36.05
mg/l
—
7
48
8
35
2.30
1.27
1.9
1.7
72.50
94.14
umol/l
—
8
35
56
433
1.31
1.13
1.5
1.4
—
—
—
0
0
7
32
2.20
1.08
1.0
1.2
—
—
—
0
0
99
828
1.22
1.06
1.5
1.4
—
—
—
0
0
67
539
1.26
1.02
1.7
2.1
317.47
159.86
ug/g
0.75
51
436
23
155
1.50
1.02
3.0
2.6
—
—
—
0
0
96
806
1.22
1.00
1.3
1.2
27.05
37.87
iu/ml
0.79
26
261
26
181
1.45
0.99
4.2
5.0
2.68
2.50
mmol/l
0.14
14
121
48
372
1.31
0.98
2.7
2.5
—
—
—
0
0
9
50
1.81
0.97
3.4
2.6
—
—
—
0
0
7
37
1.90
0.94
1.1
1.2
—
—
—
0
0
34
252
1.36
0.93
4.6
2.8
0.20
0.26
g/l
0.59
15
96
25
178
1.42
0.87
1.4
1.6
16101.37
20998.62
e6/l
0.40
16
130
17
113
1.52
0.82
10.9
2.8
—
—
—
0
0
20
138
1.46
0.82
1.6
1.5
—
—
—
0
0
8
47
1.71
0.81
1.6
1.2
—
—
—
0
0
10
58
1.73
0.80
1.2
1.7
—
—
—
0
0
11
66
1.68
0.79
1.5
1.3
265.64
275.35
mosm/kgh2o
0.70
11
43
26
191
1.37
0.78
1.5
1.4
—
—
—
0
0
333
3125
1.11
0.76
4.9
5.5
5.00
5.00
ug/l
0.00
294
2737
53
433
1.24
0.75
2.9
3.3
—
—
—
0
0
11
67
1.65
0.75
3.1
3.6
—
—
—
0
0
12
75
1.61
0.75
1.3
1.1
—
—
—
0
0
5
24
2.09
0.74
1.0
3.2
—
—
—
0
0
7
39
1.80
0.72
3.6
3.6
—
—
—
0
0
17
117
1.46
0.72
6.3
3.1
51.76
59.67
%
1.19
17
117
29
221
1.32
0.70
4.9
4.5
7.42
7.42
ph
0.14
22
194
12
78
1.55
0.65
1.3
1.3
—
—
—
0
0
23
172
1.35
0.64
3.0
2.8
—
—
—
0
0
46
379
1.23
0.63
3.5
3.8
—
—
—
0
0
21
156
1.36
0.61
2.5
2.2
123.07
127.12
g/l
0.27
15
116
67
575
1.18
0.61
12.1
4.0
1.21
1.22
mmol/l
0.68
62
501
8
51
1.57
0.60
1.3
1.3
—
—
—
0
0
8
51
1.57
0.60
1.8
1.8
9.61
10.65
%
—
8
51
8
51
1.57
0.60
1.0
1.3
—
—
—
0
0
90
793
1.15
0.59
1.2
1.2
13.63
15.21
u/ml
0.07
34
282
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
8
53
1.51
0.58
1.9
2.8
—
—
—
0
0
21
160
1.32
0.54
3.3
2.4
15.10
15.66
%
—
9
74
35
288
1.22
0.51
1.2
1.2
—
—
—
0
0
66
578
1.15
0.49
1.1
1.4
—
—
—
0
0
19
145
1.32
0.49
4.5
4.0
41.06
30.83
mg/l
0.51
13
92
20
154
1.31
0.49
1.1
1.1
—
—
—
0
0
7
49
1.43
0.46
1.1
1.3
—
—
—
0
0
12
164
0.73
0.45
1.2
1.2
—
—
—
0
0
21
165
1.28
0.45
4.9
4.4
—
—
—
0
0
15
112
1.35
0.45
1.6
1.6
—
—
—
0
0
45
386
1.18
0.44
2.8
3.0
—
—
—
0
0
5
31
1.62
0.43
1.0
1.5
0.90
0.97
g/l
—
5
31
17
131
1.30
0.42
1.5
1.5
—
—
—
0
0
11
150
0.73
0.41
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
3.8
3.5
—
—
—
0
0
166
1772
0.92
0.41
2.9
3.3
0.69
0.83
ug/l
1.35
116
1263
0
16
0.00
0.41
0.0
1.1
—
2.77
—
0
10
8
59
1.36
0.41
1.1
1.3
—
—
—
0
0
74
664
1.13
0.41
2.0
2.2
0.19
0.20
g/l
0.27
69
610
0
17
0.00
0.40
0.0
1.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.3
—
—
—
0
0
82
741
1.12
0.40
1.3
1.5
—
—
—
0
0
26
214
1.22
0.40
2.8
4.8
—
—
—
0
0
30
251
1.20
0.39
1.2
1.2
91.61
144.26
iu/ml
—
8
89
29
242
1.21
0.39
3.8
3.2
0.73
0.81
nmol/l
0.50
22
186
41
354
1.17
0.39
2.6
3.1
4.59
5.50
e9/l
0.44
26
267
17
133
1.28
0.38
1.7
2.5
—
—
—
0
0
9
67
1.35
0.38
1.1
1.0
—
—
—
0
0
15
116
1.30
0.37
2.1
2.7
—
—
—
0
0
5
37
1.35
0.37
3.4
1.2
—
—
—
0
0
12
90
1.34
0.36
1.5
1.4
—
—
—
0
0
5
77
0.65
0.36
1.2
1.5
178.00
338.94
pmol/l
—
5
77
6
43
1.40
0.35
1.0
1.1
—
—
—
0
0
156
1656
0.93
0.34
3.9
3.2
—
—
—
0
0
15
118
1.28
0.33
3.6
2.1
—
—
—
0
0
13
101
1.29
0.32
1.5
1.5
—
—
—
0
0
7
96
0.73
0.31
1.3
1.4
—
—
—
0
0
7
54
1.30
0.30
1.0
1.1
—
—
—
0
0
10
75
1.34
0.30
2.1
2.2
—
—
—
0
0
7
56
1.25
0.29
1.3
1.7
3.86
3.98
mg/l
—
7
51
7
57
1.23
0.29
1.6
1.9
1.11
2.67
ug/l
—
7
52
15
121
1.24
0.28
1.5
1.5
—
—
—
0
0
38
338
1.13
0.27
2.2
2.5
—
29.12
—
0
17
29
254
1.15
0.25
2.6
2.1
—
—
—
0
0
9
74
1.22
0.25
2.3
4.6
402.67
363.93
umol/l
—
9
67
11
87
1.27
0.24
7.8
5.3
—
—
—
0
0
13
158
0.82
0.23
1.7
1.4
—
—
—
0
0
24
210
1.15
0.22
1.2
1.3
—
—
—
0
0
19
163
1.17
0.21
1.6
1.6
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
7259.45
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
159
1527
1.05
0.21
1.7
1.6
1.37
1.28
mmol/l
0.68
138
1261
29
324
0.89
0.20
1.1
1.2
—
—
—
0
0
6
51
1.18
0.19
1.2
2.8
—
—
—
0
0
58
540
1.08
0.19
1.6
1.5
—
—
—
0
0
168
1620
1.05
0.19
4.4
3.7
—
—
—
0
0
7
60
1.17
0.18
1.0
1.3
—
—
—
0
0
6
77
0.78
0.15
1.2
1.1
—
—
—
0
0
10
83
1.21
0.15
1.5
1.7
367.30
274.51
mu/l
—
10
75
12
102
1.18
0.15
1.1
1.1
—
—
—
0
0
56
532
1.06
0.12
5.5
4.1
—
—
—
0
0
11
95
1.16
0.11
1.9
2.0
179.91
219.63
pmol/l
0.91
11
87
12
105
1.14
0.11
1.4
1.6
—
—
—
0
0
5
44
1.14
0.10
3.4
1.3
—
—
—
0
0
5
48
1.04
0.09
3.4
1.2
—
—
—
0
0
5
48
1.04
0.09
3.4
1.2
—
—
—
0
0
9
85
1.06
0.07
1.7
1.6
—
—
—
0
0
8
95
0.84
0.06
1.3
1.3
—
—
—
0
0
12
109
1.10
0.06
1.0
1.2
—
—
—
0
0
50
489
1.02
0.03
2.3
2.1
11.07
12.08
nmol/l
0.36
39
419
10
101
0.99
0.00
1.2
1.8
—
—
—
0
0
11
109
1.01
0.00
2.5
2.8
—
—
—
0
0
46
461
1.00
0.00
1.6
1.5
—
—
—
0
0
7
73
0.96
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
1.64
—
0
7
0
8
0.00
-0.00
0.0
3.0
—
1.01
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
-0.00
1.1
1.3
—
—
—
0
0
12
120
1.00
-0.00
1.5
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
4.5
—
6.66
—
0
6
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_CENTRRETARTOCC and mortality.

Females

Parameter HR [95% CI] p-value
H7_CENTRRETARTOCC 1.489 [1.29, 1.71] < 0.001
Birth year 0.99 [0.98, 1.0] 0.027

During the follow-up period (1.1.1998 — 31.12.2019), 869 out of 1918 females with H7_CENTRRETARTOCC died.

Males

Parameter HR [95% CI] p-value
H7_CENTRRETARTOCC 1.483 [1.29, 1.7] < 0.001
Birth year 0.989 [0.98, 1.0] 0.015

During the follow-up period (1.1.1998 — 31.12.2019), 1259 out of 2717 males with H7_CENTRRETARTOCC died.

Mortality risk

Mortality risk for people of age

years, who have H7_CENTRRETARTOCC.

N-year risk Females Males
1 0.101% 0.298%
5 0.648% 1.86%
10 1.66% 4.71%
15 3.185% 8.66%
20 5.884% 14.684%

Relationships between endpoints

↥

Index endpoint: H7_CENTRRETARTOCC – Central retinal artery occlusion

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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