Lung Abscess: Solitary or multiple collections of PUS within the lung parenchyma as a result of infection by bacteria, protozoa, or other agents.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
532 |
4. Check minimum number of eventsNone |
532 |
5. Include endpointsNone |
532 |
6. Filter based on genotype QC (FinnGen only) |
532 |
Control definitions (FinnGen only)
- Control exclude
- J10_NECROTIC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Abscess of lung
based on the number of shared cases.
Similar with more cases:
- Suppurative and necrotic conditions of lower respiratory tract
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5076 | 1557 | 3417 |
| Only index persons | 3512 | 1180 | 2332 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.04 | 0.10 |
| Only index persons | 0.07 | 0.04 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 60.33 | 62.79 | 59.15 |
| Only index persons | 58.66 | 60.67 | 57.65 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 532 | 158 | 374 |
| Unadjusted period prevalence (%) | 0.13 | 0.05 | 0.16 |
| Median age at first event (years) | 60.59 | 57.66 | 61.82 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 472
- Matched controls
- 4718
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
+∞
280.0
240
*
J85.2
ICD-10 Finland
Abscess of lung without pneumonia
+∞
237.1
207
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
8.4
97.4
299
802
J86.9
ICD-10 Finland
Pyothorax without fistula
+∞
85.0
79
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
16.1
81.9
140
120
UGC12
NOMESCO Finland
Flexible bronchoscopy
10.5
70.8
152
205
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
7.5
56.7
151
278
J01MA14
ATC
moxifloxacin; systemic
8.0
55.4
139
233
J01FF01
ATC
clindamycin; systemic
4.6
49.2
232
820
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
6.7
46.2
132
260
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
35.6
151
451
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
34.8
281
1429
GD1AD
NOMESCO Finland
Thorax CT examination
9.2
34.4
75
95
J01MA12
ATC
levofloxacin; systemic
4.0
33.4
166
569
51399
ICD-8 Finland
Abscess of lung
+∞
28.4
27
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.1
27.4
94
220
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
13.3
26.1
46
38
JN4BD
NOMESCO Finland
Extensive body CT
4.4
24.4
97
262
5130A
ICD-9 Finland
Abscess of lung and mediastinum, Abscess of lung
+∞
24.2
23
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.8
22.4
107
340
TGC00
NOMESCO Finland
Bronchial lavation
9.0
20.7
44
53
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
10.0
19.0
38
41
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
18.1
115
446
R03BB04
ATC
tiotropium bromide; inhalant
3.5
17.9
93
313
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
8.9
17.8
38
46
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
8.8
16.8
36
44
N02AA05
ATC
oxycodone; systemic
3.0
16.8
108
421
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
6.4
16.5
44
75
J86.00
ICD-10 Finland
Empyema with broncho-pleural fistula
+∞
14.7
14
*
GDC00
NOMESCO Finland
Lobectomy of lung
17.7
14.4
22
13
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
14.0
14.4
24
18
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
14.1
87
327
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.9
14.1
59
165
EBA15
NOMESCO Finland
Extraction of large number of teeth
5.7
13.8
40
76
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
13.7
124
587
GAC46
NOMESCO Finland
Partial decortication of pleura
77.4
13.7
15
*
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
+∞
13.6
13
*
H02AB06
ATC
prednisolone; systemic
2.1
13.5
239
1544
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
6.5
13.1
34
56
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
17.3
13.1
20
12
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.5
13.1
116
543
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.0
13.0
42
91
R4110
NOMESCO Finland
Physiotherapy
2.3
12.7
145
768
130
Kela drug reimbursment
Malignant tumour
3.3
12.3
64
213
WX892
NOMESCO Finland
Monitored bed care
3.5
12.2
59
186
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.7
12.2
88
365
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
11.9
148
811
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.9
11.9
78
303
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.5
11.7
106
498
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
11.7
96
429
J02AC03
ATC
voriconazole; systemic
122.9
11.5
12
*
N03AX16
ATC
pregabalin; oral
2.3
11.3
122
625
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.5
11.1
52
160
N05AH04
ATC
quetiapine; oral
2.5
11.0
92
414
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.0
10.9
44
119
R50.9
ICD-10 Finland
Fever, unspecified
2.6
10.7
82
351
A03FA01
ATC
metoclopramide; systemic, rectal
2.3
10.3
102
499
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.9
10.2
41
111
N05BA01
ATC
diazepam; systemic, rectal
2.6
10.1
79
341
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
10.0
95
453
R04.2
ICD-10 Finland
Haemoptysis
4.3
10.0
36
88
N02AX02
ATC
tramadol; systemic, rectal
1.9
10.0
216
1454
R03DA04
ATC
theophylline; systemic, rectal
3.4
9.9
48
152
A41.9
ICD-10 Finland
Sepsis, unspecified
4.4
9.9
35
84
Z51.5
ICD-10 Finland
Palliative care
3.6
9.9
44
130
F10.25
ICD-10 Finland
Alcohol dependence continuous use
7.4
9.6
22
31
R03AC02
ATC
salbutamol; inhalant
1.9
9.6
235
1646
R06.0
ICD-10 Finland
Dyspnoea
2.1
9.5
121
660
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
8.3
9.4
20
25
R81
ICPC
Pneumonia
5.2
9.4
28
56
N05AH03
ATC
olanzapine; systemic
3.6
9.3
42
126
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
9.1
229
1604
J47
ICD-10 Finland
Bronchiectasis
8.2
8.9
19
24
TGA30
NOMESCO Finland
Thoracocentesis
14.4
8.7
14
10
WX730
NOMESCO Finland
Conventional respirator
6.4
8.7
22
36
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
8.7
65
275
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
3.0
8.6
49
174
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
8.4
99
518
GAC96
NOMESCO Finland
Other operation on pleura
+∞
8.4
8
*
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
5.6
8.2
23
43
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.4
8.1
38
118
N03AG01
ATC
valproic acid; systemic, rectal
3.4
8.1
38
118
GAC97
NOMESCO Finland
Other endoscopic operation on pleura
34.0
8.1
10
*
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
7.2
7.8
18
26
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.8
7.8
32
89
N06AX11
ATC
mirtazapine; oral
1.9
7.8
141
874
AA1BD
NOMESCO Finland
Extensive CT of head and brain
4.9
7.7
24
51
P01AB01
ATC
metronidazole; oral, rectal
1.8
7.7
162
1052
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
7.6
49
189
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.8
7.6
49
189
JN4CD
NOMESCO Finland
Very extensive body CT
3.8
7.6
31
86
J43.9
ICD-10 Finland
Emphysema, unspecified
5.6
7.6
21
39
A02BC02
ATC
pantoprazole; systemic
1.7
7.6
288
2241
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
9.1
7.6
15
17
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
10.3
7.6
14
14
N07BB01
ATC
disulfiram; oral
3.2
7.6
38
125
J01FA06
ATC
roxithromycin; oral
1.8
7.5
179
1215
N05AH02
ATC
clozapine; systemic
6.1
7.5
19
32
N06AB04
ATC
citalopram; systemic
2.0
7.4
103
577
JN4AD
NOMESCO Finland
Body CT examination
2.7
7.3
48
188
J15.1
ICD-10 Finland
Pneumonia due to Pseudomonas
+∞
7.3
7
*
WX872
NOMESCO Finland
Intensive care
3.1
7.3
38
129
F29
ICD-10 Finland
Unspecified nonorganic psychosis
4.5
7.2
24
55
GDA20
NOMESCO Finland
Excision of lesion of lung
30.5
7.2
9
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
7.1
58
256
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
4.6
7.1
23
52
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.0
7.0
38
132
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.8
7.0
45
174
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
4.8
7.0
22
48
N05CF01
ATC
zopiclone; oral
1.8
7.0
153
1004
H02AB07
ATC
prednisone; oral
2.1
6.9
77
395
R03AC12
ATC
salmeterol; inhalant
3.4
6.9
32
100
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
9.5
6.8
13
14
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
6.8
88
479
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.1
6.8
25
64
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
7.3
6.8
15
21
C03CA01
ATC
furosemide; systemic
1.8
6.7
151
995
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
4.7
6.7
21
46
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
6.7
91
507
B01AB05
ATC
enoxaparin; parenteral
1.8
6.6
139
895
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
12.5
6.6
11
9
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.7
6.5
42
163
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.7
6.5
27
77
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
14.6
6.4
10
7
A28
ICPC
Limited function/disability NOS
2.0
6.4
80
430
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
6.3
134
868
B18.2
ICD-10 Finland
Chronic viral hepatitis C
9.4
6.3
12
13
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.9
6.3
19
40
GDB20
NOMESCO Finland
Segmental resection of lung
+∞
6.3
6
*
B44.0
ICD-10 Finland
Invasive pulmonary aspergillosis
+∞
6.3
6
*
GAC43
NOMESCO Finland
Total decortication of pleura
+∞
6.3
6
*
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
7.8
6.2
13
17
N05AA02
ATC
levomepromazine; systemic
2.9
6.1
35
126
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
157
159
13.59
145.00
3.2
3.0
—
—
—
0
0
80
45
20.75
101.15
4.2
4.3
—
—
—
0
0
106
109
11.90
95.15
1.7
1.3
—
—
—
0
0
58
48
13.44
59.15
1.4
1.3
18675.6
1642.7
e6/l
1.05
46
31
64
64
11.23
57.76
1.3
1.1
—
—
—
0
0
193
684
3.86
46.08
2.7
1.9
—
—
—
0
0
48
44
11.89
45.70
1.4
1.3
26536.8
44258.1
e6/l
0.58
33
24
74
123
6.83
43.90
1.8
1.7
—
—
—
0
0
60
89
7.47
39.44
1.3
1.5
—
—
—
0
0
179
662
3.57
39.22
6.9
3.9
0.8
0.8
mmol/l
5.00
169
624
147
482
3.83
38.56
2.5
1.9
—
—
—
0
0
146
487
3.75
37.22
2.5
1.9
—
—
—
0
0
106
286
4.38
36.27
1.9
1.7
—
—
—
0
0
122
384
3.82
33.59
7.2
7.3
1.4
1.4
mmol/l
0.03
116
370
150
545
3.44
33.15
9.7
6.7
1.0
1.0
mmol/l
0.34
141
508
333
1912
2.98
32.49
12.4
6.5
23.2
27.3
%
7.87
327
1787
53
85
6.81
32.31
1.9
1.5
—
—
—
0
0
61
116
5.81
31.36
2.0
1.8
—
—
—
0
0
60
114
5.81
30.87
2.0
1.8
—
—
—
0
0
134
479
3.40
30.12
3.9
4.5
235.5
248.4
u/l
0.39
128
451
51
85
6.53
29.93
2.1
1.8
—
—
—
0
0
324
1886
2.84
29.87
12.0
6.3
61.6
57.5
%
6.53
317
1773
103
320
3.75
28.62
2.3
2.9
61.7
66.6
g/l
5.90
97
294
133
488
3.30
28.52
7.5
7.5
1.4
1.3
mmol/l
0.07
114
392
43
64
7.22
28.01
2.0
1.6
—
—
—
0
0
363
2289
2.84
27.85
19.9
9.8
5.4
4.2
e9/l
11.94
333
2013
44
68
6.96
27.70
2.0
1.5
—
—
—
0
0
132
492
3.24
27.50
7.4
7.4
5.3
5.1
kpa
0.61
125
473
132
493
3.23
27.39
7.4
7.4
11.0
11.8
kpa
1.02
124
477
45
73
6.64
27.06
2.0
1.6
—
—
—
0
0
71
175
4.53
26.97
2.6
2.0
1.2
1.6
ug/l
0.20
65
157
39
55
7.57
26.63
2.1
1.8
—
—
—
0
0
24
18
13.92
25.54
4.4
5.1
—
—
—
0
0
25
21
12.44
24.89
2.5
1.6
—
—
—
0
0
25
21
12.44
24.89
2.5
1.6
—
—
—
0
0
109
384
3.31
24.72
5.9
4.8
1.8
1.8
mmol/l
0.01
89
301
109
388
3.28
24.28
5.9
4.8
5.8
5.7
kpa
0.28
104
375
77
224
3.85
23.33
7.6
10.3
24.9
24.7
mmol/l
0.11
71
212
296
1801
2.45
22.57
12.2
6.5
1.2
1.2
mmol/l
4.61
279
1631
57
138
4.51
22.05
1.8
1.8
—
151.4
—
0
7
26
28
9.71
21.92
2.5
1.5
—
—
—
0
0
39
68
6.11
21.80
2.3
1.7
—
—
—
0
0
330
2150
2.41
20.99
10.2
6.9
10.0
12.4
umol/l
2.56
320
2041
42
84
5.34
20.32
1.6
1.4
—
—
—
0
0
42
84
5.34
20.32
1.6
1.4
—
—
—
0
0
27
35
8.07
19.71
2.4
1.5
—
—
—
0
0
305
1957
2.31
19.58
11.7
7.3
1.2
1.2
mmol/l
3.77
261
1651
283
1765
2.29
19.38
8.6
5.2
30.4
35.3
g/l
20.69
270
1653
69
211
3.61
19.33
6.9
5.3
23.6
24.2
mmol/l
0.55
63
194
130
602
2.53
17.30
3.6
2.5
2.1
2.3
g/l
3.21
118
564
21
24
9.07
16.88
1.4
1.2
—
—
—
0
0
30
52
6.05
16.83
1.3
2.0
11.7
16.9
ug/l
2.74
30
52
34
67
5.35
16.69
3.2
3.5
59.9
59.4
%
0.05
34
67
123
573
2.49
16.05
3.8
2.6
19.1
23.8
%
3.06
102
491
60
190
3.43
15.87
1.6
2.0
1.8
1.5
g/l
1.01
46
164
242
1502
2.12
15.79
4.6
3.4
—
—
—
0
0
29
52
5.84
15.71
1.8
1.6
—
—
—
0
0
70
247
3.11
15.52
2.2
1.5
—
—
—
0
0
133
653
2.38
15.41
3.6
2.5
9.8
13.1
umol/l
6.67
121
609
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
51
149
3.68
15.22
3.4
2.5
0.3
0.4
u/ml
1.11
30
77
198
1153
2.14
15.11
3.9
3.4
0.5
0.5
e6/l
0.06
156
865
38
91
4.42
14.84
3.0
2.1
123.5
127.2
g/l
0.33
24
66
93
394
2.65
14.69
2.7
2.5
0.2
0.2
g/l
1.40
82
365
180
1020
2.16
14.66
3.0
2.0
2.9
3.1
mg/l
0.38
157
874
71
262
2.97
14.54
2.1
1.7
—
—
—
0
0
15
14
11.00
13.81
1.0
1.3
160.9
14.9
ug/l
—
5
5
42
117
3.81
13.41
3.5
3.7
32.7
35.9
umol/l
0.35
33
100
17
23
7.60
11.90
32.9
21.1
1680.9
1662.1
nmol/l
0.02
17
23
208
1324
1.94
11.77
4.9
3.3
2.3
2.3
mmol/l
2.96
189
1162
330
2445
1.92
11.69
9.6
5.0
7.1
6.8
mmol/l
0.93
321
2306
212
1370
1.91
11.37
4.6
3.6
37.2
35.4
u/l
0.20
206
1305
91
428
2.36
11.37
2.8
4.7
4.9
37.0
ug/l
1.08
78
364
28
65
4.49
11.36
2.8
3.1
5.4
4.7
e9/l
0.51
28
65
162
964
1.98
11.05
3.6
2.5
—
—
—
0
0
148
861
2.00
10.72
2.3
1.8
1.7
1.3
mg/l
0.50
128
676
81
374
2.38
10.52
2.5
2.1
380.9
363.7
nmol/l
0.17
74
343
90
436
2.28
10.46
6.3
3.4
—
—
—
0
0
197
1284
1.85
10.01
3.6
2.7
54.5
57.6
u/l
0.64
188
1196
335
2589
1.79
9.38
6.3
4.4
295.5
2607.4
e6/l
0.79
11
54
386
3116
1.87
9.32
15.3
7.9
86.0
80.0
u/l
1.94
377
2921
94
487
2.13
9.21
3.4
3.3
8.5
9.0
umol/l
0.09
77
433
30
86
3.64
9.20
4.4
2.4
14.9
15.7
%
0.40
16
45
67
302
2.39
9.15
6.8
4.0
2.4
2.0
mmol/l
0.25
45
222
123
714
1.94
8.78
3.0
3.2
1.1
1.0
e6/l
0.14
63
426
118
686
1.93
8.35
3.3
3.4
1.9
1.4
e6/l
0.44
59
400
18
39
4.74
7.93
1.1
1.4
—
—
—
0
0
21
53
4.08
7.68
1.6
2.0
—
—
—
0
0
67
326
2.21
7.65
7.0
3.8
5.0
5.1
kpa
0.49
62
303
74
375
2.13
7.63
3.5
2.5
29.0
34.2
u/l
0.72
67
320
22
58
3.91
7.60
1.5
1.9
—
—
—
0
0
334
3936
0.59
7.41
4.7
4.5
1.4
1.4
mmol/l
1.40
303
3615
130
810
1.80
7.31
4.6
3.9
215.3
459.9
ng/l
0.99
106
659
34
122
2.91
7.31
2.9
4.3
159.1
115.8
mg/l
0.14
27
99
34
122
2.91
7.31
2.9
4.3
31.9
37.4
mg/l
0.44
27
99
18
43
4.30
7.06
1.7
1.7
—
—
—
0
0
18
43
4.30
7.06
1.7
1.7
—
—
—
0
0
18
43
4.30
7.06
1.7
1.7
—
—
—
0
0
45
193
2.45
6.85
4.2
3.9
25.8
24.7
mmol/l
0.77
45
186
123
768
1.78
6.82
2.1
1.7
1234.6
1144.6
nmol/l
0.53
95
589
181
1260
1.66
6.76
3.0
2.1
237.2
300.5
u/l
0.36
171
1183
14
28
5.11
6.74
1.7
2.6
12.8
14.7
%
—
6
15
14
28
5.11
6.74
1.7
2.6
—
—
—
0
0
120
752
1.77
6.55
4.6
3.1
2.5
2.4
mmol/l
1.12
107
655
353
2913
1.63
6.45
6.3
4.1
23.4
12.4
mm/h
14.19
342
2670
145
963
1.70
6.42
1.9
1.6
19.2
20.1
nmol/l
0.37
135
816
10
15
6.78
6.33
1.6
1.3
—
—
—
0
0
26
87
3.09
6.31
7.5
7.2
434.3
178.4
iu/ml
—
7
16
35
139
2.62
6.24
1.4
2.4
3.5
3.1
g/l
1.06
27
110
34
135
2.62
6.07
1.4
2.4
9.7
10.7
g/l
0.40
27
118
343
3958
0.62
6.00
4.7
4.5
4.4
4.5
mmol/l
1.74
314
3657
244
1869
1.56
5.95
5.7
4.2
—
—
—
0
0
12
24
5.09
5.77
1.7
1.7
—
—
—
0
0
12
24
5.09
5.77
1.7
1.7
—
—
—
0
0
12
24
5.09
5.77
1.7
1.7
—
—
—
0
0
12
24
5.09
5.77
1.7
1.7
—
—
—
0
0
56
285
2.08
5.70
5.4
4.5
107.7
86.2
ng/l
0.62
47
252
16
42
3.90
5.57
1.1
1.5
—
—
—
0
0
32
129
2.58
5.56
1.5
1.2
—
—
—
0
0
35
148
2.46
5.51
1.4
2.3
—
—
—
0
0
35
148
2.46
5.51
1.4
2.3
3.9
3.7
g/l
0.28
27
107
35
148
2.46
5.51
1.4
2.3
8.3
7.3
g/l
2.06
28
112
31
124
2.59
5.47
1.9
2.7
0.1
1.1
g/l
2.14
26
111
37
163
2.36
5.34
2.8
1.9
—
—
—
0
0
28
108
2.68
5.31
1.6
1.4
—
—
—
0
0
200
1500
1.53
5.17
2.6
2.3
71.8
76.3
nmol/l
1.31
191
1331
35
153
2.38
5.15
2.1
1.7
—
—
—
0
0
10
19
5.34
5.06
1.2
1.2
277.9
145.1
iu/ml
—
10
19
333
3814
0.66
4.87
4.4
4.1
1.4
1.3
mmol/l
0.42
300
3489
10
354
0.27
4.68
1.4
1.8
—
—
—
0
0
29
122
2.46
4.64
1.4
1.5
0.0
0.1
iu/ml
—
6
24
15
43
3.56
4.64
1.1
1.1
—
—
—
0
0
120
1677
0.63
4.62
3.8
4.2
18.0
21.0
%
1.16
46
770
10
21
4.83
4.55
1.7
1.7
—
—
—
0
0
10
21
4.83
4.55
1.7
1.7
—
—
—
0
0
211
1638
1.48
4.47
5.5
3.9
68.2
48.8
ng/l
0.37
158
1178
360
4038
0.66
4.45
5.1
5.0
2.5
2.7
mmol/l
3.75
328
3709
11
26
4.30
4.37
1.5
1.7
—
—
—
0
0
209
1626
1.47
4.36
2.5
2.0
87.1
93.6
pmol/l
1.43
127
871
10
22
4.61
4.32
1.7
1.7
—
—
—
0
0
16
51
3.20
4.24
1.2
1.3
—
—
—
0
0
161
2076
0.68
4.05
4.2
4.8
2.1
2.5
ug/l
0.56
132
1857
17
59
2.94
3.93
1.2
1.1
—
—
—
0
0
15
50
3.06
3.71
9.3
8.5
8.3
7.3
mmol/l
0.39
15
43
78
507
1.63
3.64
2.3
2.0
2.0
1.6
%
3.06
66
445
203
1617
1.41
3.56
4.3
2.7
167.5
165.0
ug/l
0.05
188
1482
16
57
2.86
3.55
1.3
1.3
1.0
7.1
u/ml
—
6
17
23
99
2.38
3.55
1.9
1.8
—
—
—
0
0
38
204
1.93
3.40
8.7
4.8
24.0
25.1
mmol/l
0.73
33
193
334
3732
0.72
3.28
6.8
6.0
41.5
40.4
mmol/mol
0.91
301
3470
354
3910
0.72
3.15
5.0
4.6
6.2
6.0
mmol/l
0.83
323
3560
16
62
2.63
3.07
1.2
1.3
2.7
5.2
u/ml
—
7
26
55
342
1.68
3.06
3.8
3.0
341.1
199.5
ng/l
0.79
49
303
89
1230
0.67
3.03
2.6
2.9
0.6
0.8
ug/l
1.88
61
777
7
12
5.89
3.03
1.3
1.3
—
—
—
0
0
10
31
3.27
2.78
1.3
1.3
—
—
—
0
0
5
6
8.40
2.75
1.0
1.3
41.2
35.7
umol/l
—
5
6
6
10
6.05
2.70
1.7
1.4
—
—
—
0
0
110
821
1.43
2.70
1.8
1.8
473.4
5822839.8
pmol/l
0.50
92
687
158
1257
1.37
2.66
4.2
3.2
1687.7
1569.2
ng/l
0.12
150
1079
5
7
7.20
2.55
1.0
1.1
—
—
—
0
0
10
34
2.98
2.42
1.5
3.3
—
—
—
0
0
6
12
5.04
2.41
4.0
3.7
—
—
—
0
0
6
12
5.04
2.41
4.0
3.7
—
—
—
0
0
9
27
3.37
2.40
1.4
1.1
—
—
—
0
0
22
111
2.02
2.39
1.8
1.5
169.2
264.1
ug/g
1.37
13
67
11
41
2.72
2.29
2.5
2.0
—
—
—
0
0
222
1890
1.30
2.28
6.8
5.1
0.0
0.0
estimate
0.00
57
350
223
1901
1.30
2.27
4.8
3.6
0.0
0.0
estimate
0.00
53
348
270
2360
1.29
2.26
3.3
2.8
—
—
—
0
0
224
1917
1.29
2.19
5.0
3.7
0.0
0.0
estimate
0.50
55
332
428
3993
1.37
2.17
43.7
15.3
45.1
25.8
mg/l
17.29
407
3199
129
1024
1.34
2.17
5.6
3.8
0.0
0.0
estimate
0.50
50
337
7
19
3.72
2.15
1.0
1.1
—
—
—
0
0
8
25
3.23
2.10
7.0
3.6
—
—
—
0
0
7
20
3.53
2.06
2.9
4.2
97.3
89.8
%
—
7
20
100
771
1.37
2.03
1.4
1.2
1.6
1.4
u/ml
0.16
21
197
6
17
3.56
1.84
1.0
1.2
—
—
—
0
0
5
12
4.20
1.82
1.0
1.0
—
—
—
0
0
17
87
1.99
1.81
1.8
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
6
19
3.18
1.66
1.0
1.2
—
—
—
0
0
8
31
2.60
1.66
1.9
1.5
—
—
—
0
0
16
85
1.91
1.56
1.8
1.3
—
—
—
0
0
5
15
3.35
1.52
1.0
1.4
—
—
—
0
0
7
27
2.61
1.52
1.0
1.4
1.3
2.9
u/field
—
7
19
5
16
3.14
1.44
2.0
2.5
—
—
—
0
0
37
522
0.69
1.40
3.7
4.5
33.7
30.9
%
0.62
26
357
12
60
2.02
1.39
1.0
1.1
—
—
—
0
0
16
90
1.80
1.34
1.3
1.3
159.2
272.5
miu/ml
—
5
38
5
18
2.79
1.28
9.2
1.3
—
—
—
0
0
18
107
1.71
1.27
1.3
1.2
—
—
—
0
0
6
25
2.42
1.24
2.2
3.0
28.0
53.9
u/ml
—
6
25
18
108
1.69
1.23
1.2
1.2
—
—
—
0
0
5
19
2.65
1.22
1.8
2.3
—
—
—
0
0
5
20
2.51
1.15
2.2
2.4
36.0
49.2
umol/l
—
5
15
7
30
2.35
1.12
1.0
1.1
—
—
—
0
0
8
40
2.01
1.12
1.0
1.2
—
—
—
0
0
5
23
2.18
0.98
1.8
1.3
2.6
1.9
mmol/l
—
5
23
432
4155
1.21
0.96
43.3
17.7
138.5
139.7
mmol/l
10.74
427
4048
101
861
1.21
0.96
6.5
4.0
1.0
1.0
kg/l
0.02
20
135
71
583
1.25
0.96
24.8
24.4
1.6
1.3
inr
—
10
76
91
1058
0.83
0.86
1.7
1.7
1.4
1.4
mmol/l
0.15
76
888
18
262
0.68
0.86
2.2
2.5
—
13.1
—
0
16
432
4170
1.19
0.84
43.9
17.8
4.0
4.0
mmol/l
0.08
426
4065
47
381
1.26
0.73
3.0
2.6
10.5
8.8
ug/l
0.22
40
339
5
25
2.01
0.73
1.4
2.4
—
—
—
0
0
5
25
2.01
0.73
1.4
2.4
—
—
—
0
0
162
1475
1.14
0.70
5.5
3.8
—
—
—
0
0
17
238
0.70
0.69
1.3
1.3
—
33.9
—
0
18
143
1293
1.14
0.69
4.7
3.4
6.5
8.1
mmol/l
4.69
125
1081
286
2704
1.12
0.67
5.2
3.3
91.4
53.5
u/l
3.57
273
2539
435
4465
0.86
0.66
57.3
22.2
125.1
137.3
g/l
35.02
429
4392
435
4464
0.86
0.65
56.9
22.1
4.2
4.5
e12/l
28.01
425
4341
435
4461
0.86
0.62
57.6
22.1
283.8
241.2
e9/l
16.73
426
4346
8
49
1.64
0.62
1.3
1.1
—
—
—
0
0
40
483
0.81
0.58
13.1
7.6
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
49
576
0.84
0.55
1.3
1.3
26.6
9.4
u/ml
0.39
15
223
294
2805
1.11
0.55
4.3
3.4
14.9
14.8
pmol/l
0.30
268
2522
6
39
1.54
0.53
1.0
1.0
—
—
—
0
0
66
576
1.17
0.52
1.3
1.5
—
—
—
0
0
38
315
1.22
0.52
2.6
3.0
55.6
64.0
ml/min/173m2
0.49
18
136
9
64
1.41
0.51
1.3
1.6
—
—
—
0
0
13
92
1.42
0.51
1.7
1.7
1421.8
458.6
mg/l
0.55
13
87
13
92
1.42
0.51
1.3
1.3
—
—
—
0
0
21
165
1.28
0.45
1.2
1.3
—
—
—
0
0
15
112
1.35
0.45
1.7
1.9
—
—
—
0
0
388
3776
1.10
0.43
35.0
13.9
83.8
79.8
ml/min/173m2
2.32
341
3115
13
96
1.36
0.42
1.1
1.1
—
—
—
0
0
15
115
1.31
0.39
4.2
2.3
—
—
—
0
0
13
170
0.76
0.38
1.2
1.0
—
—
—
0
0
9
70
1.29
0.37
5.6
2.8
56.5
5.8
u/ml
—
9
65
6
44
1.37
0.34
1.2
1.3
0.8
0.6
nmol/l
—
6
39
419
4264
0.92
0.32
20.1
10.8
25.0
28.1
u/l
3.93
410
4121
29
249
1.17
0.31
7.0
2.9
0.8
0.2
e6/l
0.45
29
241
13
102
1.28
0.30
2.3
1.6
—
—
—
0
0
10
76
1.32
0.28
1.7
1.2
20.8
39.6
u/l
—
10
66
135
1285
1.07
0.25
5.0
4.0
27.0
9.9
mg/mmol
1.03
100
844
12
96
1.26
0.24
1.2
1.3
—
—
—
0
0
11
137
0.80
0.24
1.6
1.6
—
—
—
0
0
5
40
1.25
0.22
1.4
1.3
—
—
—
0
0
15
178
0.84
0.22
1.3
1.7
43.1
38.8
nmol/l
0.48
15
171
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
12
100
1.20
0.18
1.8
1.4
—
—
—
0
0
7
59
1.19
0.18
1.9
1.4
—
—
—
0
0
11
91
1.21
0.17
1.8
1.9
—
—
—
0
0
7
61
1.15
0.17
1.9
1.4
—
—
—
0
0
7
61
1.15
0.17
1.9
1.4
—
—
—
0
0
7
61
1.15
0.17
1.9
1.4
—
—
—
0
0
7
61
1.15
0.17
1.9
1.4
—
—
—
0
0
7
62
1.13
0.17
1.9
1.4
—
—
—
0
0
5
66
0.76
0.17
1.4
1.3
—
—
—
0
0
8
70
1.15
0.16
1.4
1.1
—
—
—
0
0
19
212
0.89
0.14
1.2
1.3
53.8
134.2
iu/ml
—
5
81
9
108
0.83
0.13
1.1
1.1
—
10.5
—
0
10
12
104
1.16
0.12
1.5
1.4
—
—
—
0
0
58
609
0.95
0.12
1.3
1.3
24.3
36.6
iu/ml
0.88
22
195
43
452
0.95
0.09
1.8
2.3
13.0
13.6
nmol/l
0.19
32
403
28
299
0.93
0.09
1.4
1.4
—
—
—
0
0
6
57
1.05
0.08
1.3
1.1
—
—
—
0
0
109
1112
0.98
0.06
4.4
2.9
373.6
7627.8
umol/l
4.58
91
973
25
261
0.96
0.04
1.5
1.7
—
—
—
0
0
367
3654
1.01
0.03
41.5
16.2
37.4
40.2
%
7.63
254
2632
352
3514
1.01
0.00
5.2
4.2
1.8
2.3
mu/l
0.73
318
3182
30
300
1.00
0.00
1.6
1.8
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
30.5
—
0
5
0
5
0.00
0.00
0.0
2.8
—
0.4
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
2.8
3.5
3.4
6.9
nmol/l
—
5
52
0
6
0.00
0.00
0.0
1.0
—
13.1
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
3.4
—
83.8
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint J10_ABSCLUNGPNEUMO and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_ABSCLUNGPNEUMO | 4.25 [3.11, 5.8] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.069 |
During the follow-up period (1.1.1998 — 31.12.2019), 385 out of 944 females with J10_ABSCLUNGPNEUMO died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_ABSCLUNGPNEUMO | 4.708 [3.8, 5.83] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 890 out of 2011 males with J10_ABSCLUNGPNEUMO died.
Mortality risk
Mortality risk for people of age
years, who have J10_ABSCLUNGPNEUMO.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.272% | 1.001% |
| 5 | 1.99% | 5.415% |
| 10 | 5.023% | 14.01% |
| 15 | 10.22% | 24.788% |
| 20 | 16.725% | 38.003% |
Relationships between endpoints
↥Index endpoint: J10_ABSCLUNGPNEUMO – Abscess of lung
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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