No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
437 |
4. Check minimum number of eventsNone |
437 |
5. Include endpointsNone |
437 |
6. Filter based on genotype QC (FinnGen only) |
437 |
Control definitions (FinnGen only)
- Control exclude
- AB1_VIRAL_SKIN_MUCOUS_MEMBRANE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Measles
based on the number of shared cases.
Similar with more cases:
- Viral infections characterized by skin and mucous membrane lesions
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4026 | 1752 | 2266 |
| Only index persons | 3751 | 1644 | 2107 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.05 | 0.06 |
| Only index persons | 0.07 | 0.06 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 6.89 | 6.79 | 6.96 |
| Only index persons | 6.86 | 6.74 | 6.95 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 437 | 250 | 187 |
| Unadjusted period prevalence (%) | 0.08 | 0.09 | 0.08 |
| Median age at first event (years) | 8.22 | 8.38 | 8.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 403
- Matched controls
- 4027
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
05599
ICD-8 Finland
Measles, Non definita
+∞
256.6
218
*
05597
ICD-8 Finland
Measles, Suspecta
+∞
141.2
127
*
38100
ICD-8 Finland
Otitis media without mention of mastoiditis, Acute
10.6
31.5
63
69
0559X
ICD-9 Finland
Measles without mention of complication
+∞
17.8
17
*
46599
ICD-8 Finland
Acute upper respiratory infection of multiple or unspecified sites
4.8
15.8
54
125
00920
ICD-8 Finland
Diarrhoeal disease, Gastroenteritis (acuta) (infectiosa)
5.0
12.4
40
87
48609
ICD-8 Finland
Pneumonia, unspecified
6.6
12.2
31
50
78020
ICD-8 Finland
Certain symptoms referable to nervous system and special senses, Convulsions
9.2
10.4
21
24
48509
ICD-8 Finland
Bronchopneumonia, unspecified
6.4
9.8
25
41
B05.9
ICD-10 Finland
Measles without complication
+∞
9.4
9
*
05209
ICD-8 Finland
Chickenpox, Unspecified
+∞
9.4
9
*
46699
ICD-8 Finland
Acute bronchitis and bronchiolitis
6.7
8.6
21
33
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
2.4
8.6
79
376
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
4.7
8.5
28
63
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
+∞
8.4
8
*
46309
ICD-8 Finland
Acute tonsillitis, Unspecified
4.7
7.2
23
51
07999
ICD-8 Finland
Other viral diseases, Viral infection, unspecified
12.3
7.1
12
10
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.1
6.5
34
116
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
6.4
134
871
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.6
6.3
20
45
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
6.1
84
474
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
4.7
6.1
19
42
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
110
603
2.10
9.55
2.4
2.1
3.0
2.9
mg/l
0.21
96
522
154
1036
1.75
6.86
2.0
1.7
97.6
97.4
pmol/l
0.02
94
596
210
1555
1.67
6.48
3.4
2.7
131.3
104.6
ug/l
0.93
197
1485
145
976
1.73
6.36
2.7
3.4
2.3
2.3
mmol/l
0.22
134
899
123
795
1.76
6.21
1.7
1.7
0.6
0.8
mg/l
0.61
99
599
169
1217
1.63
5.60
5.9
4.9
36.2
37.2
g/l
1.50
158
1165
67
372
1.95
5.44
2.0
1.6
1179.8
1149.1
nmol/l
0.12
59
301
63
347
1.95
5.23
3.8
2.5
25.9
24.7
%
0.22
56
296
72
430
1.81
4.66
3.4
2.3
14.3
15.0
umol/l
0.27
66
399
12
29
4.23
4.65
1.6
1.2
—
—
—
0
0
88
563
1.71
4.48
2.5
2.9
778.2
687.5
ng/l
0.08
70
450
65
385
1.81
4.32
3.6
2.4
2.4
2.5
g/l
0.72
59
358
20
76
2.71
3.95
1.5
2.3
1.5
1.4
g/l
0.14
20
67
84
551
1.65
3.87
1.7
1.5
19.0
21.6
nmol/l
0.85
77
497
13
40
3.32
3.65
2.5
2.2
17.4
16.6
%
—
8
25
169
1319
1.46
3.51
2.8
2.3
70.4
72.8
nmol/l
0.53
158
1244
216
1769
1.44
3.45
5.4
4.5
6.9
6.5
mmol/l
1.31
205
1676
109
784
1.52
3.37
3.8
3.1
0.0
0.0
estimate
0.50
41
278
102
725
1.53
3.33
1.3
1.3
36.9
26.0
iu/ml
0.42
27
261
69
448
1.64
3.30
2.5
2.9
2.4
2.4
mmol/l
0.11
62
399
56
349
1.69
3.13
1.9
2.2
320.1
365.5
nmol/l
1.46
50
329
129
977
1.45
3.06
3.8
2.7
—
—
—
0
0
21
95
2.27
2.94
1.4
1.3
—
—
—
0
0
120
908
1.44
2.84
2.6
2.0
345.0
4073.9
umol/l
2.16
108
835
43
256
1.75
2.83
3.6
2.9
—
—
—
0
0
292
2580
1.40
2.73
4.7
3.7
10.6
8.6
mm/h
2.34
275
2459
13
49
2.70
2.64
4.0
3.0
—
1228.0
—
0
5
34
194
1.82
2.59
1.9
1.6
—
—
—
0
0
131
1023
1.40
2.58
4.0
2.6
54.3
55.9
u/l
0.25
125
974
7
16
4.43
2.48
3.1
2.9
673.1
761.7
u/ml
—
7
16
94
696
1.45
2.48
1.3
1.2
3.4
11.3
u/ml
1.61
36
336
16
72
2.27
2.30
1.5
1.2
—
—
—
0
0
11
41
2.73
2.29
1.2
1.2
—
—
—
0
0
57
394
1.51
2.12
2.9
2.3
6.9
6.8
umol/l
0.02
50
347
197
1684
1.31
2.06
6.0
5.8
9.5
10.8
umol/l
2.24
192
1622
11
44
2.54
2.02
1.1
1.2
—
—
—
0
0
39
252
1.60
1.95
3.1
3.9
4.5
4.6
pmol/l
0.18
26
221
21
116
1.85
1.82
1.8
1.6
1.7
1536.1
u/l
—
5
35
186
1599
1.28
1.80
3.6
2.8
0.0
0.0
estimate
0.50
40
267
75
565
1.40
1.80
1.8
1.6
486.1
14175180.4
pmol/l
0.50
66
515
8
29
2.79
1.80
1.0
1.0
—
—
—
0
0
24
139
1.77
1.79
1.9
1.4
—
—
—
0
0
11
47
2.38
1.79
1.1
1.3
—
—
—
0
0
185
1592
1.28
1.77
4.7
3.8
0.0
0.0
estimate
0.50
46
283
134
1109
1.30
1.73
3.2
2.7
27.6
33.2
ng/l
0.18
70
547
35
229
1.57
1.68
4.5
3.4
3.1
2.1
mmol/l
0.76
27
192
113
920
1.31
1.64
2.5
2.0
240.9
170.0
u/l
0.29
103
884
82
639
1.35
1.60
1.7
2.0
1.4
1.4
%
0.12
75
592
103
831
1.31
1.59
1.3
1.3
1.1
2.2
u/ml
0.74
33
246
6
20
3.03
1.58
1.0
1.1
—
—
—
0
0
165
1417
1.26
1.57
4.7
3.6
—
—
—
0
0
48
343
1.45
1.55
5.8
5.4
—
—
—
0
0
47
335
1.45
1.54
4.3
3.5
29.2
30.5
%
0.31
35
255
26
162
1.64
1.53
3.0
2.3
250.9
79.2
ng/l
1.02
20
137
7
27
2.62
1.52
1.1
2.0
—
—
—
0
0
6
21
2.88
1.51
1.0
1.6
—
—
—
0
0
182
1587
1.25
1.50
3.6
2.8
0.0
0.0
estimate
0.00
44
278
223
1995
1.24
1.45
10.7
9.4
4.2
3.9
e9/l
1.10
200
1772
6
22
2.75
1.44
2.3
2.5
—
—
—
0
0
90
724
1.31
1.42
3.6
2.5
0.2
0.3
e6/l
0.66
73
538
141
1208
1.25
1.34
8.8
5.9
1.2
1.2
mmol/l
0.11
128
1108
15
83
1.84
1.33
1.0
1.4
6.5
7.1
g/l
—
10
62
15
83
1.84
1.33
1.0
1.4
—
—
—
0
0
13
69
1.91
1.30
3.1
5.0
56.5
58.3
%
0.24
13
69
13
69
1.91
1.30
3.2
4.2
3.9
4.3
e9/l
0.33
13
69
351
3673
0.77
1.29
16.6
11.1
41.3
41.5
%
0.27
287
3128
354
3356
1.29
1.28
6.2
4.4
41.4
38.4
mmol/mol
4.77
337
3214
40
288
1.43
1.27
4.2
2.9
37.7
51.1
u/l
0.38
35
249
30
204
1.51
1.26
1.7
1.7
—
—
—
0
0
106
886
1.26
1.24
1.9
1.7
1.5
1.5
mmol/l
0.15
87
783
10
49
2.07
1.23
1.2
1.1
—
—
—
0
0
36
258
1.43
1.18
2.3
1.6
—
—
—
0
0
55
424
1.34
1.18
1.8
1.7
—
—
—
0
0
8
39
2.07
1.16
1.3
1.9
—
—
—
0
0
398
3848
1.38
1.14
4.6
4.1
2.8
3.0
mmol/l
3.73
372
3690
7
30
2.35
1.13
1.1
1.2
—
—
—
0
0
7
30
2.35
1.13
1.1
1.2
—
—
—
0
0
13
73
1.80
1.12
2.1
1.8
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
7
31
2.28
1.11
1.1
1.2
—
—
—
0
0
50
384
1.34
1.10
2.3
1.7
—
—
—
0
0
7
32
2.21
1.08
1.1
1.2
—
80.0
—
0
5
24
162
1.51
1.06
1.6
1.7
—
—
—
0
0
146
1284
1.21
1.05
3.5
2.8
—
—
—
0
0
279
2603
1.20
1.04
8.9
6.9
79.5
75.6
u/l
0.83
270
2486
394
3813
1.34
1.03
4.4
3.9
4.7
4.9
mmol/l
2.97
369
3675
14
83
1.71
1.02
1.0
1.4
4.0
3.8
g/l
—
9
58
15
91
1.67
1.02
1.1
1.1
0.3
2.6
u/ml
—
6
37
60
480
1.29
1.01
2.0
1.8
—
—
—
0
0
384
3706
1.30
1.00
4.0
3.5
1.4
1.4
mmol/l
0.68
361
3549
5
23
2.19
0.98
1.0
1.0
—
—
—
0
0
345
3295
1.22
0.95
4.9
4.5
1.7
2.1
mu/l
0.68
322
3148
18
117
1.56
0.95
1.2
1.1
—
—
—
0
0
11
62
1.79
0.95
2.0
1.5
—
112.7
—
0
12
297
2800
1.19
0.93
4.2
4.0
14.6
14.3
pmol/l
0.97
281
2666
50
395
1.30
0.93
3.1
2.3
1.7
2.5
e6/l
0.58
27
195
9
52
1.75
0.93
1.0
1.0
1.4
1.5
g/l
—
9
46
13
79
1.67
0.89
2.7
2.1
350.0
325.0
ug/l
0.04
13
70
379
3664
1.26
0.88
16.2
10.8
139.4
139.7
mmol/l
2.24
368
3599
392
3805
1.29
0.87
4.4
3.8
1.4
1.4
mmol/l
0.93
368
3652
35
265
1.35
0.87
2.3
1.6
—
—
—
0
0
8
45
1.79
0.84
2.6
1.5
—
—
—
0
0
65
539
1.24
0.83
3.7
3.2
121.4
263.6
ng/l
0.63
40
344
16
105
1.54
0.83
1.0
1.1
—
—
—
0
0
6
32
1.89
0.82
1.2
1.7
—
—
—
0
0
79
671
1.22
0.81
2.7
3.0
1.0
1.0
kg/l
0.04
11
79
52
422
1.26
0.80
2.6
2.2
0.9
1.1
e6/l
0.22
30
223
36
278
1.32
0.80
5.7
10.5
1.2
1.2
mmol/l
0.01
29
216
16
106
1.53
0.80
1.0
1.1
—
—
—
0
0
11
66
1.68
0.79
1.3
1.2
—
—
—
0
0
12
186
0.64
0.78
1.6
1.5
—
—
—
0
0
328
3141
1.18
0.76
18.6
12.9
13.5
13.5
%
0.06
321
3094
9
53
1.71
0.76
1.9
1.1
—
—
—
0
0
9
53
1.71
0.76
1.9
1.1
—
—
—
0
0
7
38
1.86
0.74
1.1
1.8
1.2
1.4
nmol/l
—
7
32
5
25
2.01
0.73
1.2
1.1
—
—
—
0
0
9
56
1.62
0.72
1.7
2.4
—
4.2
—
0
5
360
3480
1.20
0.72
13.1
9.1
90.4
89.7
ml/min/173m2
0.27
314
2935
150
1366
1.15
0.68
9.9
6.7
1.2
1.2
mmol/l
0.44
124
1163
5
30
1.67
0.61
2.0
1.1
—
—
—
0
0
77
673
1.17
0.60
3.8
2.1
—
—
—
0
0
8
53
1.52
0.58
1.4
1.5
—
—
—
0
0
18
132
1.38
0.58
1.4
1.2
—
—
—
0
0
90
802
1.15
0.56
1.5
1.5
—
—
—
0
0
6
37
1.63
0.55
1.2
1.4
—
—
—
0
0
9
61
1.49
0.54
1.2
1.8
—
—
—
0
0
9
61
1.49
0.54
1.2
1.8
—
—
—
0
0
11
74
1.50
0.54
1.1
1.2
—
—
—
0
0
15
108
1.40
0.54
1.3
1.5
0.3
0.2
g/l
0.21
15
101
377
3682
1.17
0.52
16.8
10.9
3.9
3.9
mmol/l
0.10
364
3608
7
47
1.50
0.47
1.9
2.3
—
—
—
0
0
15
111
1.36
0.47
1.3
1.5
1.3
1.2
g/l
0.09
15
103
362
3538
1.14
0.43
4.3
3.7
6.1
5.8
mmol/l
3.52
329
3369
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
15
0.00
0.41
0.0
1.0
—
128.7
—
0
15
0
15
0.00
0.41
0.0
1.0
—
98.0
—
0
10
0
15
0.00
0.41
0.0
1.0
—
109.1
—
0
10
373
3655
1.14
0.41
16.5
10.7
20.5
19.9
mg/l
0.12
300
2817
72
797
0.88
0.40
2.7
2.8
17.9
21.6
%
2.16
24
224
30
252
1.20
0.39
2.3
2.3
72.3
77.8
ml/min/173m2
0.22
12
95
18
143
1.27
0.37
1.6
1.3
33.0
232.5
miu/ml
—
6
74
16
125
1.29
0.37
2.2
3.0
49.6
53.2
%
0.31
16
125
5
37
1.36
0.37
1.2
1.5
—
—
—
0
0
23
192
1.21
0.32
1.7
1.6
—
—
—
0
0
74
678
1.11
0.32
1.4
1.4
—
—
—
0
0
27
230
1.19
0.31
3.8
4.4
5.6
13.5
ug/l
0.54
14
176
12
93
1.30
0.30
1.6
1.5
—
—
—
0
0
18
148
1.23
0.29
7.8
11.6
1.4
1.7
%
0.97
18
148
18
148
1.23
0.29
8.5
11.6
0.8
0.7
%
0.53
18
148
18
149
1.22
0.28
8.5
11.7
94.0
93.4
%
0.20
18
149
300
2932
1.07
0.26
3.4
3.0
50.0
46.9
u/l
0.22
287
2847
5
38
1.32
0.23
1.4
1.4
—
—
—
0
0
14
116
1.21
0.22
2.8
1.6
—
—
—
0
0
17
144
1.19
0.22
1.1
1.3
12.6
10.4
u/l
0.17
11
123
5
41
1.22
0.22
2.0
1.4
0.9
1.0
g/l
—
5
41
5
41
1.22
0.22
1.0
1.3
—
—
—
0
0
5
42
1.19
0.21
1.0
1.3
—
—
—
0
0
5
42
1.19
0.21
1.0
1.3
—
—
—
0
0
5
42
1.19
0.21
1.0
1.3
—
—
—
0
0
5
42
1.19
0.21
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
417
4197
0.86
0.21
22.5
15.5
138.8
140.1
g/l
0.99
412
4161
39
359
1.09
0.17
2.3
2.3
13.2
14.1
nmol/l
0.39
33
340
46
427
1.09
0.17
1.3
1.3
31.0
31.7
iu/l
0.05
39
380
8
68
1.18
0.16
3.3
2.4
—
—
—
0
0
26
287
0.90
0.16
1.2
1.2
144.8
155.9
iu/ml
0.06
13
125
303
2987
1.05
0.15
3.3
3.4
—
—
—
0
0
15
164
0.91
0.08
1.5
1.4
—
—
—
0
0
7
67
1.05
0.08
6.1
5.8
386.3
370.8
umol/l
—
7
58
12
133
0.90
0.07
1.6
2.1
—
—
—
0
0
8
75
1.07
0.07
1.0
1.1
—
—
—
0
0
8
78
1.03
0.07
1.1
1.3
—
—
—
0
0
401
3996
1.04
0.05
11.3
8.8
29.8
29.8
u/l
0.00
391
3929
13
140
0.93
0.04
3.2
1.8
199.8
208.8
pmol/l
0.12
13
130
21
218
0.96
0.02
1.5
1.4
—
—
—
0
0
100
990
1.01
0.02
2.5
2.8
1.6
1.4
ug/l
0.73
91
918
60
609
0.98
0.02
2.2
2.2
0.6
0.6
ug/l
0.10
29
274
13
123
1.06
0.01
2.5
1.7
—
—
—
0
0
61
618
0.98
0.01
1.6
1.8
—
—
—
0
0
10
101
0.99
0.00
1.9
1.7
—
—
—
0
0
6
62
0.97
0.00
1.5
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
55
0.91
0.00
1.6
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
—
—
—
0
0
5
52
0.96
0.00
1.2
1.6
—
—
—
0
0
5
59
0.85
0.00
1.0
1.2
8.0
7.5
mmol/l
—
5
42
0
9
0.00
0.00
0.0
1.0
—
1.2
—
0
9
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
106.7
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
22
220
1.00
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
0.4
—
0
7
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
9
93
0.97
0.00
2.0
1.5
—
—
—
0
0
7
75
0.93
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
7
69
1.01
0.00
1.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_MEASLES and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have AB1_MEASLES.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: AB1_MEASLES – Measles
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data