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This is a non-core endpoint: only basic statistics are computed.

Toxic effect of other gases, fumes and vapours

ST19_TOXIC_EFFECT_OTHER_GASES_FUMES_VAPOU

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 T59
  • Cause of death: ICD-10 T59

2 out of 7 registries used, show all original rules.

205

4. Check minimum number of events

None

205

5. Include endpoints

None

205

6. Filter based on genotype QC (FinnGen only)

205

Control definitions (FinnGen only)

Control exclude
ST19_TOXIC_EFFEC_SUBST_CHIEF_NONME_SOURCE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
T5[1-9]|T6[0-5]
Name in latin
Effectus toxicus aliorum gasorum, fumorum et vaporum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 205 78 127
Unadjusted period prevalence (%) 0.04 0.03 0.06
Median age at first event (years) 45.79 44.78 46.42

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
183
Matched controls
1830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T59.8
ICD-10 Finland
Toxic effect: Other specified gases, fumes and vapours
+∞
92.8
81
*
T59.9
ICD-10 Finland
Toxic effect: Gases, fumes and vapours, unspecified
+∞
35.6
33
*
T59.7
ICD-10 Finland
Toxic effect: Carbon dioxide
+∞
30.0
28
*
X09
ICD-10 Finland
Exposure to unspecified smoke, fire and flames
261.4
23.2
23
*
X47
ICD-10 Finland
Accidental poisoning by and exposure to carbon monoxide and other gases and vapours
+∞
19.1
18
*
T59.0
ICD-10 Finland
Toxic effect: Nitrogen oxides
+∞
13.7
13
*
T59.4
ICD-10 Finland
Toxic effect: Chlorine gas
+∞
13.7
13
*
X00
ICD-10 Finland
Exposure to uncontrolled fire in building or structure
+∞
9.5
9
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
8.5
9.4
20
26
R06.0
ICD-10 Finland
Dyspnoea
3.1
9.2
60
251
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
8.3
8.9
19
25
N05CF01
ATC
zopiclone; oral
2.7
8.3
67
319
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.6
8.0
37
120
J96.1
ICD-10 Finland
Chronic respiratory failure
10.7
7.7
14
14
X49
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
26.3
7.7
10
*
T59.5
ICD-10 Finland
Toxic effect: Fluorine gas and hydrogen fluoride
+∞
7.3
7
*
N05AH04
ATC
quetiapine; oral
3.0
7.3
47
191
P29
ICPC
Psychological sympt/compl other
5.5
7.0
20
40
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
7.0
86
502
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
9.9
6.9
13
14
N05AA02
ATC
levomepromazine; systemic
6.4
6.5
16
27
F61.0
ICD-10 Finland
Mixed personality disorders
9.8
6.4
12
13
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
18.8
6.3
9
5
T58
ICD-10 Finland
Toxic effect of carbon monoxide
+∞
6.3
6
*
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
27.7
6.3
8
*
N05BA01
ATC
diazepam; systemic, rectal
3.2
6.3
32
112
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
7.1
6.2
14
21
F10.20
ICD-10 Finland
Alcohol dependence currently independent
9.1
6.2
12
14

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
95
553
2.34
8.08
5.5
3.4
24.4
45.0
ng/l
1.54
66
366
36
134
3.05
7.57
3.9
3.6
—
—
—
0
0
25
74
3.71
7.52
2.8
2.2
1.8
1.3
%
0.78
25
74
34
130
2.94
6.80
4.1
3.3
2.5
2.2
mmol/l
0.22
28
99
18
48
4.01
6.24
2.4
3.7
—
—
—
0
0
25
91
2.99
5.43
2.0
2.6
—
—
—
0
0
14
35
4.22
5.26
4.2
20.7
1.2
1.2
mmol/l
0.02
14
30
18
57
3.37
4.89
2.3
13.8
2.2
1.6
%
1.35
18
51
76
478
1.94
4.72
3.2
2.6
52.8
55.3
u/l
0.35
71
452
22
81
2.92
4.69
1.8
2.7
—
—
—
0
0
25
99
2.74
4.67
2.0
2.1
—
—
—
0
0
25
99
2.74
4.67
2.1
2.5
—
—
—
0
0
25
99
2.74
4.67
2.0
2.5
—
—
—
0
0
25
99
2.74
4.67
2.0
2.5
—
—
—
0
0
23
88
2.82
4.58
2.4
9.9
—
—
—
0
0
32
147
2.39
4.43
8.7
11.1
5.4
5.1
kpa
0.62
32
138
32
147
2.39
4.43
8.7
11.1
12.2
11.9
kpa
0.08
32
140
65
401
1.91
4.21
5.4
4.0
—
—
—
0
0
31
148
2.29
3.94
8.9
11.1
1.8
1.1
mmol/l
0.40
23
117
58
358
1.86
3.70
3.5
2.7
—
—
—
0
0
11
30
3.82
3.69
4.6
2.2
2.9
2.9
mmol/l
—
5
19
21
87
2.58
3.61
4.0
13.0
25.2
24.6
mmol/l
0.37
21
79
87
614
1.72
3.50
8.0
6.3
1.2
1.2
mmol/l
1.86
81
569
10
27
3.84
3.40
3.2
1.7
—
—
—
0
0
26
127
2.20
3.13
9.5
12.4
126.6
125.1
g/l
0.12
26
122
146
1207
1.73
3.12
9.1
7.0
74.9
76.7
u/l
0.28
139
1140
11
35
3.26
2.97
4.0
4.5
29.1
36.0
umol/l
0.99
11
29
72
506
1.65
2.83
7.4
5.6
—
—
—
0
0
65
447
1.66
2.77
3.9
2.1
178.8
270.0
u/l
0.91
59
428
105
816
1.59
2.71
8.3
6.2
10.3
11.4
umol/l
0.86
98
778
16
68
2.47
2.63
12.5
16.4
—
—
—
0
0
12
44
2.83
2.59
1.6
1.2
—
—
—
0
0
14
56
2.61
2.59
2.6
14.1
0.9
0.9
%
0.18
14
51
24
124
2.06
2.53
10.2
6.4
1.0
1.5
mmol/l
2.42
24
119
37
223
1.80
2.50
1.9
1.6
—
—
—
0
0
23
118
2.07
2.47
12.2
7.4
—
—
—
0
0
38
232
1.78
2.46
2.0
1.7
1339.3
1151.8
nmol/l
0.47
26
181
9
27
3.44
2.42
2.4
1.5
64.8
65.6
%
—
9
27
32
187
1.84
2.38
1.3
1.4
608.0
494.5
titre
—
5
44
41
261
1.71
2.30
3.5
3.5
441.5
222.0
ng/l
0.37
27
192
181
1639
1.89
2.28
23.0
12.5
22.0
23.8
mg/l
0.33
146
1276
99
780
1.52
2.28
7.7
5.8
0.6
0.6
e9/l
1.27
87
679
71
521
1.55
2.26
2.2
1.9
99.0
93.3
pmol/l
0.51
40
263
99
783
1.51
2.22
7.7
5.8
0.0
0.0
e9/l
0.35
87
682
45
298
1.65
2.18
3.1
2.4
498.7
575.1
mosm/kgh2o
1.33
38
252
101
805
1.50
2.17
7.7
5.8
1.9
1.9
e9/l
0.09
90
713
101
810
1.49
2.08
7.8
6.3
0.2
0.2
e9/l
0.07
90
716
31
188
1.76
2.06
9.8
6.6
105.1
104.0
mmol/l
0.64
31
182
9
32
2.89
2.02
2.2
3.3
—
—
—
0
0
95
756
1.48
2.02
8.0
5.8
27.8
28.0
%
0.09
90
707
35
222
1.70
1.99
2.6
2.1
—
—
—
0
0
5
11
4.63
1.95
5.2
1.5
—
—
—
0
0
60
438
1.52
1.92
2.9
3.3
8.5
8.5
mmol/l
0.01
50
370
92
733
1.46
1.92
8.7
6.1
8.8
8.6
%
0.27
86
686
29
179
1.72
1.82
2.2
1.7
—
—
—
0
0
110
914
1.44
1.80
9.0
9.4
4.1
4.1
e9/l
0.02
99
795
91
733
1.43
1.75
8.2
5.8
2.9
2.7
%
0.16
86
677
14
68
2.14
1.74
2.0
4.3
—
—
—
0
0
89
717
1.43
1.70
7.9
5.7
0.7
0.7
%
0.04
84
663
5
130
0.37
1.69
1.4
1.3
—
—
—
0
0
61
459
1.47
1.67
2.7
3.2
2.4
2.3
mmol/l
0.25
54
413
91
739
1.42
1.65
7.9
5.7
57.9
57.2
%
0.20
86
692
71
552
1.44
1.64
25.4
7.3
1.3
1.2
inr
0.36
24
174
5
14
3.63
1.62
1.8
1.3
—
—
—
0
0
60
453
1.46
1.61
3.8
2.6
11.4
56.4
e6/l
2.32
47
348
7
26
2.75
1.59
3.7
1.9
18584.1
16056.4
e6/l
—
7
16
67
520
1.43
1.55
4.7
3.1
25.7
127.0
e6/l
0.96
50
367
132
1154
1.40
1.51
4.2
3.6
14.8
14.7
pmol/l
0.05
121
1059
57
432
1.44
1.49
5.6
3.4
—
—
—
0
0
51
379
1.46
1.48
4.9
6.8
—
—
—
0
0
55
415
1.44
1.47
3.7
2.5
0.5
0.4
e6/l
0.18
39
308
11
52
2.18
1.47
1.3
1.1
—
—
—
0
0
23
142
1.70
1.46
1.4
1.5
—
—
—
0
0
15
81
1.92
1.44
8.5
3.1
—
—
—
0
0
9
40
2.31
1.42
1.4
1.2
—
—
—
0
0
42
303
1.49
1.41
2.6
2.2
1.8
4.4
e6/l
4.64
37
265
27
177
1.61
1.37
1.2
1.2
—
—
—
0
0
53
404
1.42
1.34
3.7
2.5
—
—
—
0
0
48
363
1.42
1.26
2.4
1.9
—
—
—
0
0
8
36
2.27
1.25
1.6
1.3
—
—
—
0
0
6
25
2.44
1.25
1.0
1.1
—
—
—
0
0
6
25
2.44
1.25
2.5
3.8
—
—
—
0
0
43
321
1.43
1.21
2.2
1.8
1.2
1.2
mg/l
0.00
27
254
5
20
2.54
1.16
6.8
2.9
3.9
4.0
mmol/l
—
5
20
5
20
2.54
1.16
6.8
2.9
—
—
—
0
0
5
20
2.54
1.16
6.8
2.9
103.6
107.5
mmol/l
—
5
20
11
58
1.95
1.14
2.8
4.2
—
—
—
0
0
26
367
0.67
1.13
2.4
2.6
0.6
0.7
ug/l
0.41
16
215
53
416
1.37
1.12
4.1
3.9
6.5
10.4
mg/mmol
0.53
37
278
119
1051
1.32
1.12
5.4
3.9
—
—
—
0
0
57
454
1.35
1.10
3.3
2.3
—
—
—
0
0
26
181
1.50
1.05
4.2
3.0
5.6
7.2
umol/l
0.60
21
159
9
48
1.91
1.02
2.1
3.7
4.3
3.9
mmol/l
—
9
42
49
390
1.34
0.95
3.9
2.6
362.7
5802.2
umol/l
1.31
42
338
27
194
1.45
0.94
4.3
1.9
2.4
2.4
g/l
0.01
22
183
154
1428
1.32
0.92
5.2
4.2
1.6
1.9
mu/l
2.79
145
1312
37
284
1.37
0.90
2.3
1.6
—
—
—
0
0
53
640
0.77
0.88
3.4
2.5
—
—
—
0
0
6
30
2.03
0.87
1.0
1.4
—
—
—
0
0
19
129
1.52
0.87
14.1
6.5
10.1
8.1
mmol/l
0.74
19
124
25
182
1.43
0.83
4.8
1.9
20.7
23.9
%
0.52
19
161
6
33
1.84
0.79
1.0
1.1
—
—
—
0
0
6
33
1.84
0.79
1.0
1.1
—
—
—
0
0
117
1061
1.24
0.78
3.4
3.4
—
—
—
0
0
126
1152
1.24
0.77
5.0
3.7
10.8
10.2
mm/h
0.15
116
1068
14
91
1.58
0.77
1.3
1.1
—
—
—
0
0
6
34
1.79
0.77
1.5
1.3
—
—
—
0
0
86
758
1.23
0.73
4.6
3.1
0.0
0.0
estimate
0.00
19
144
16
109
1.51
0.73
1.7
1.2
135.9
136.3
iu/ml
—
8
40
42
341
1.29
0.72
3.1
1.9
3.6
3.1
mg/l
0.60
36
296
5
26
1.95
0.71
4.8
2.8
—
—
—
0
0
48
398
1.27
0.70
5.3
3.3
0.0
0.0
estimate
0.00
18
139
155
1458
1.26
0.70
21.8
14.9
334.2
334.3
g/l
0.02
155
1452
10
62
1.64
0.66
1.6
2.2
—
—
—
0
0
48
402
1.25
0.64
3.5
3.8
7.4
7.4
ph
0.02
13
76
5
29
1.74
0.64
1.4
1.1
—
—
—
0
0
73
643
1.21
0.61
4.0
2.5
141.6
128.1
ug/l
0.18
68
599
8
51
1.59
0.61
1.0
1.2
—
—
—
0
0
8
53
1.53
0.59
1.1
1.2
—
—
—
0
0
34
276
1.28
0.59
1.9
1.7
507.3
461.9
pmol/l
0.45
29
248
6
35
1.74
0.58
1.7
1.3
—
—
—
0
0
23
177
1.34
0.58
1.3
1.8
—
—
—
0
0
18
133
1.39
0.57
5.1
3.0
—
—
—
0
0
50
427
1.23
0.57
1.4
1.5
—
—
—
0
0
79
706
1.19
0.56
12.3
8.8
0.0
0.0
e9/l
0.47
64
566
46
390
1.23
0.56
3.3
3.3
34.2
231.6
mg/l
0.61
32
261
20
152
1.35
0.54
2.4
2.1
310.5
392.3
nmol/l
1.56
20
142
40
335
1.24
0.54
1.4
1.4
2.7
2.3
g/l
0.71
25
216
161
1536
1.22
0.54
4.3
4.0
6.1
5.9
mmol/l
0.67
149
1410
16
119
1.37
0.50
3.8
4.7
0.0
0.2
%
—
7
39
50
434
1.20
0.49
3.9
2.9
—
—
—
0
0
17
130
1.34
0.45
12.3
4.1
—
—
—
0
0
17
130
1.34
0.45
3.6
4.6
1.0
0.9
%
—
7
44
83
757
1.16
0.45
6.2
4.4
0.0
0.0
estimate
0.00
19
144
21
166
1.30
0.45
1.4
1.3
—
—
—
0
0
21
166
1.30
0.45
1.5
1.3
—
—
—
0
0
84
768
1.16
0.44
4.7
3.2
0.0
0.0
estimate
0.00
18
137
5
31
1.63
0.43
1.0
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
284.4
—
0
11
0
16
0.00
0.41
0.0
2.8
—
2.5
—
0
16
5
36
1.40
0.38
1.2
1.2
—
—
—
0
0
5
36
1.40
0.38
2.6
3.4
25.6
23.9
mmol/l
—
5
30
15
116
1.32
0.38
4.3
3.1
—
—
—
0
0
6
43
1.41
0.35
2.5
3.4
—
—
—
0
0
23
192
1.22
0.34
1.6
1.5
—
—
—
0
0
41
364
1.16
0.32
1.3
1.3
0.8
1.3
u/ml
1.06
12
107
20
239
0.82
0.32
1.4
1.3
35.6
9.7
u/ml
—
10
94
62
568
1.13
0.31
1.9
1.9
—
—
—
0
0
7
53
1.33
0.31
2.4
1.8
—
—
—
0
0
151
1458
1.14
0.31
5.8
5.0
39.4
39.6
mmol/mol
0.09
143
1374
25
213
1.20
0.31
2.2
2.2
101.4
126.4
ug/g
0.23
19
164
22
185
1.21
0.30
2.7
1.8
—
—
—
0
0
17
205
0.81
0.29
1.6
1.5
—
—
—
0
0
11
85
1.31
0.28
1.0
1.1
—
—
—
0
0
8
64
1.26
0.28
6.4
11.8
—
—
—
0
0
13
104
1.27
0.27
1.6
3.4
66.3
67.1
g/l
0.11
13
96
178
1742
1.17
0.27
20.4
11.2
—
—
—
0
0
9
77
1.18
0.24
4.2
3.6
—
—
—
0
0
5
42
1.20
0.21
5.0
5.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
12.5
—
0
11
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
60
637
0.92
0.19
3.6
3.9
1.4
1.7
ug/l
0.77
53
574
21
237
0.87
0.19
1.3
1.4
—
—
—
0
0
10
82
1.23
0.17
1.6
1.6
—
—
—
0
0
11
92
1.21
0.16
4.5
2.2
—
—
—
0
0
6
80
0.74
0.15
1.0
1.1
—
—
—
0
0
37
345
1.09
0.14
5.2
3.1
—
—
—
0
0
27
249
1.10
0.12
1.3
1.3
27.1
32.7
iu/ml
0.18
11
83
161
1633
0.93
0.11
4.6
4.4
2.9
2.8
mmol/l
0.35
153
1516
10
87
1.16
0.09
1.8
3.2
—
—
—
0
0
18
165
1.10
0.09
1.3
1.5
—
—
—
0
0
6
54
1.11
0.09
2.0
1.7
—
—
—
0
0
6
58
1.04
0.08
2.3
1.6
—
—
—
0
0
39
374
1.05
0.07
4.9
5.0
—
—
—
0
0
159
1574
1.05
0.06
19.3
12.4
41.0
41.1
%
0.03
110
1233
159
1601
0.97
0.03
4.3
4.0
1.4
1.4
mmol/l
0.39
149
1488
160
1607
0.98
0.01
4.4
4.0
4.7
4.7
mmol/l
0.20
150
1500
11
114
0.96
0.00
1.7
1.3
—
—
—
0
0
155
1548
1.01
0.00
3.9
3.6
1.5
1.3
mmol/l
1.31
145
1437
12
118
1.02
0.00
1.4
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
0.00
1.7
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
3.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
12
120
1.00
0.00
1.1
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
5.1
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
10
100
1.00
0.00
1.3
1.3
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_TOXIC_EFFECT_OTHER_GASES_FUMES_VAPOU – Toxic effect of other gases, fumes and vapours

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).