No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
908 |
4. Check minimum number of eventsNone |
908 |
5. Include endpointsNone |
908 |
6. Filter based on genotype QC (FinnGen only) |
877 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L80-L99
- Name in latin
- Lupus erythematosus
Similar endpoints
↥List of similar endpoints to
Cutaneous lupus erythematosus
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5703 | 4197 | 1469 |
| Only index persons | 5048 | 3789 | 1259 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.10 | 0.12 | 0.04 |
| Only index persons | 0.12 | 0.14 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 54.73 | 55.76 | 51.68 |
| Only index persons | 53.96 | 55.11 | 50.50 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 877 | 669 | 208 |
| Unadjusted period prevalence (%) | 0.20 | 0.24 | 0.10 |
| Median age at first event (years) | 54.41 | 53.25 | 58.12 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 908
- Matched controls
- 9080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L93.0
ICD-10 Finland
Discoid lupus erythematosus
8399.9
307.7
719
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
25.1
307.7
449
340
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
143.5
307.7
210
19
P01BA02
ATC
hydroxychloroquine; oral
35.1
307.7
579
434
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
7.2
159.6
300
579
L30.9
ICD-10 Finland
Dermatitis, unspecified
6.0
154.0
406
1077
L93.1
ICD-10 Finland
Subacute cutaneous lupus erythematosus
+∞
149.2
139
*
D07AB08
ATC
desonide; topical
6.7
138.3
271
539
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
14.2
115.6
110
87
D07AC01
ATC
betamethasone; topical
4.7
114.5
549
2247
L93.2
ICD-10 Finland
Other local lupus erythematosus
+∞
111.8
105
*
D07AC13
ATC
mometasone; topical
4.4
107.1
476
1821
D07AD01
ATC
clobetasol; topical
4.9
106.3
318
901
L04AX01
ATC
azathioprine; systemic
9.6
97.9
123
146
L04AA06
ATC
mycophenolic acid; systemic
19.8
95.2
75
41
D07AB02
ATC
hydrocortisone butyrate; topical
4.1
94.9
457
1815
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
21.9
94.2
71
35
E0000UV, ,
ATC
3.5
75.7
543
2689
L04AX03
ATC
methotrexate; systemic
4.8
74.7
198
497
H02AB06
ATC
prednisolone; systemic
3.6
74.2
601
3195
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
5.3
68.0
154
337
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
13.1
67.4
66
54
P01BA01
ATC
chloroquine; systemic
29.5
67.1
45
16
L93
ICD-10 Finland
Lupus erythematosus
+∞
63.3
60
*
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
99.9
59.7
65
7
XQ848
NOMESCO Finland
Dermatological photography
9.0
50.3
64
76
TQW80
NOMESCO Finland
Local dermatologic skincare
10.6
49.1
55
55
E000001, ,
ATC
3.1
47.7
270
1103
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
5.5
47.2
97
193
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
165.0
45.2
47
*
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
404.2
39.4
39
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.5
39.2
430
2409
69540
ICD-8 Finland
Erythematous condition, Lupus erythematosus
+∞
37.8
36
*
D06BX01
ATC
metronidazole; topical
3.2
36.5
169
606
L71.8
ICD-10 Finland
Other rosacea
8.8
35.9
46
55
M32
ICD-10 Finland
Systemic lupus erythematosus
360.6
35.2
35
*
C08CA05
ATC
nifedipine; systemic
4.3
34.2
94
237
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
93.7
33.0
36
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
31.0
478
3010
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
36.0
29.8
38
11
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
301.2
28.9
29
*
L71.9
ICD-10 Finland
Rosacea, unspecified
5.8
28.3
53
96
D07XC01
ATC
betamethasone; topical
2.9
27.9
147
563
D02AX
ATC
Other emollients and protectives
5.4
26.7
54
105
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.4
26.6
106
344
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.3
25.6
104
342
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
10.0
25.1
29
30
L88
ICPC
Rheumatoid/seropositive arthritis
4.2
25.0
69
174
SBA10
NOMESCO Finland
Measurement of salivary flow rate
8.9
24.6
31
36
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.7
24.4
152
633
H02AB07
ATC
prednisone; oral
2.5
23.6
168
747
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.9
22.5
120
460
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
21.6
202
1011
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.0
20.8
99
356
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
20.6
146
645
L43.9
ICD-10 Finland
Lichen planus, unspecified
5.8
20.5
38
68
L04AD01
ATC
ciclosporin; systemic
6.7
20.1
32
49
D05BB02
ATC
acitretin; oral
5.6
19.9
38
70
D07AA02
ATC
hydrocortisone; topical
2.4
19.9
158
735
J04BA02
ATC
dapsone; oral
47.1
19.3
23
5
73410
ICD-8 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
102.2
18.6
20
*
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
2.1
18.6
236
1323
M05BA04
ATC
alendronic acid; oral
2.6
18.6
119
500
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.1
18.4
83
289
E000002, ,
ATC
2.5
18.2
124
537
L01BA01
ATC
methotrexate; systemic
3.9
18.0
55
149
R50.9
ICD-10 Finland
Fever, unspecified
2.3
18.0
158
765
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.7
16.9
39
85
E000007, ,
ATC
3.2
16.8
70
233
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
3.0
16.7
76
266
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.6
16.2
103
430
6954A
ICD-9 Finland
Erythematous conditions, Lupus erythematosus[LUPUS ERYTHEMATOSUS DISCOIDES]
+∞
15.7
15
*
R06AX27
ATC
desloratadine; oral
1.9
15.3
280
1760
XQ802
NOMESCO Finland
Epicutan test
3.4
15.3
56
172
M35.1
ICD-10 Finland
Other overlap syndromes
20.5
15.1
22
11
J01FF01
ATC
clindamycin; systemic
1.9
15.0
260
1606
L30.8
ICD-10 Finland
Other specified dermatitis
4.4
14.9
38
90
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
6.1
14.8
26
44
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
14.8
285
1818
A02BC02
ATC
pantoprazole; systemic
1.8
14.8
631
5059
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
14.7
52
156
XQ845
NOMESCO Finland
Dermatoscopy
5.9
14.5
26
45
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
14.3
427
3084
R06AE07
ATC
cetirizine; oral
1.7
14.1
421
3036
B07.9
ICD-10 Finland
Verruca simplex
3.7
14.0
44
122
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
5.1
13.9
29
58
XX9XE
NOMESCO Finland
Other ultrasound examination
10.7
13.8
26
25
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
13.1
13.5
23
18
L43.8
ICD-10 Finland
Other lichen planus
5.0
13.4
29
60
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.1
13.3
57
193
L56.4
ICD-10 Finland
Polymorphous light eruption
13.2
13.0
22
17
D02AE01
ATC
carbamide; topical
2.7
12.9
72
282
SBA00
NOMESCO Finland
Microbiological examinations
3.9
12.7
37
97
A02BC05
ATC
esomeprazole; systemic
1.7
12.5
386
2782
SPAT1153
SPAT
Removal of sutures
1.7
12.5
294
1970
ZXC12
NOMESCO Finland
Pulse colorlaser
20.4
12.5
18
9
D02BB01
ATC
betacarotene; oral
20.4
12.5
18
9
J01DB01
ATC
cefalexin; oral
1.9
12.5
746
6418
J05AB11
ATC
valaciclovir; oral
2.0
12.4
154
846
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
4.6
12.2
29
65
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.7
11.9
66
257
S97
ICPC
Chronic ulcer skin
2.9
11.8
55
195
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
11.7
95
443
XPX04
NOMESCO Finland
Angioscopy
30.5
11.7
15
5
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.7
11.6
275
1840
E000006, ,
ATC
2.5
11.6
76
322
A01AC01
ATC
triamcinolone; local oral
5.1
11.5
24
48
J01MA12
ATC
levofloxacin; systemic
1.9
11.5
170
990
N02AX02
ATC
tramadol; systemic, rectal
1.6
11.0
386
2849
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.6
10.7
61
241
R06AE09
ATC
levocetirizine; oral
1.9
10.7
141
789
B02.9
ICD-10 Finland
Zoster without complication
2.4
10.7
75
328
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
10.6
373
2745
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.4
10.6
73
317
H02AB04
ATC
methylprednisolone; systemic
1.9
10.5
139
778
J01AA07
ATC
tetracycline; systemic
1.9
10.5
150
861
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.0
10.5
130
712
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.2
10.5
91
436
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.9
10.5
30
78
6954B
ICD-9 Finland
Erythematous conditions, Lupus erythematosus[LUPUS ERYTHEMATOSUS DISCOIDES DISSEMINATUS]
+∞
10.4
10
*
D07AC14
ATC
methylprednisolone aceponate; topical
2.7
10.4
56
215
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.3
10.4
27
65
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.8
10.1
51
189
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.1
10.1
104
532
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.0
10.1
116
618
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.1
10.1
42
140
D10BA01
ATC
isotretinoin; oral
2.6
10.1
57
225
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.1
10.0
95
472
L04AA13
ATC
[U] leflunomide
3.4
9.9
35
105
QAA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of head or neck
16.9
9.9
15
9
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
4.1
9.8
27
68
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.0
9.7
110
583
J01DA01
ATC
[U] cefalexin
1.6
9.7
560
4592
C03CA01
ATC
furosemide; systemic
1.7
9.6
248
1684
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
9.6
124
688
L04AA01
ATC
[U] ciclosporin
5.2
9.4
19
37
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
3.1
9.3
38
125
R4120
NOMESCO Finland
Occupational therapy
2.4
9.2
66
292
M25.5
ICD-10 Finland
Pain in joint
1.6
9.2
297
2129
WZA10
NOMESCO Finland
Extensive medical or dental certificate
4.6
9.1
21
46
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
11.6
9.1
16
14
XQ800
NOMESCO Finland
Prick test
2.2
9.0
74
346
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
9.0
112
613
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
9.0
205
1347
WW200
NOMESCO Finland
Immunization
3.8
8.9
27
73
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
8.9
85
423
J05AB01
ATC
aciclovir; systemic
1.7
8.9
210
1391
A01AB04
ATC
amphotericin B; local oral
2.5
8.8
54
222
S06
ICPC
Rash localized
2.4
8.8
58
247
A07AA02
ATC
nystatin; oral
2.4
8.7
63
279
K90.0
ICD-10 Finland
Coeliac disease
3.3
8.7
33
104
E000003, ,
ATC
2.7
8.6
47
182
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
8.6
204
1351
NH3EA
NOMESCO Finland
Feet X-ray examination with load
3.7
8.6
27
75
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
11.7
8.6
15
13
S99
ICPC
Skin disease other
3.6
8.6
28
80
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.5
8.4
29
86
ZXC50
NOMESCO Finland
Cryotherapy
3.4
8.4
30
91
J01AA04
ATC
lymecycline; systemic
1.9
8.4
117
665
A02BC01
ATC
omeprazole; systemic
1.6
8.3
243
1694
S01
ICPC
Pain/tenderness of skin
2.6
8.3
46
180
UJF32
NOMESCO Finland
Coloscopy
1.6
8.3
228
1567
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
3.8
8.2
25
68
SHA03
NOMESCO Finland
Stomatognathic treatment, demanding
2.8
8.2
39
141
R60.0
ICD-10 Finland
Localized oedema
1.9
8.2
111
626
J02AC01
ATC
fluconazole; systemic
1.5
8.2
374
2877
N03AX16
ATC
[U] pregabalin
1.6
8.1
210
1419
M33.1
ICD-10 Finland
Other dermatomyositis
33.7
8.1
10
*
L94.0
ICD-10 Finland
Localized scleroderma [morphea]
33.7
8.1
10
*
QCA99
NOMESCO Finland
Other local destruction of skin of upper limb
17.4
8.1
12
7
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
8.0
316
2351
R05
ICD-10 Finland
Cough
1.6
8.0
192
1274
A46
ICD-10 Finland
Erysipelas
1.9
8.0
110
623
A02BC03
ATC
lansoprazole; oral
1.6
7.9
262
1875
L63.9
ICD-10 Finland
Alopecia areata, unspecified
13.2
7.9
13
10
J01AA02
ATC
doxycycline; systemic
1.6
7.8
695
6111
ECA20
NOMESCO Finland
Biopsy of gingiva
7.0
7.8
18
26
ZXX02
NOMESCO Finland
Extent of procedure, 2 units
4.4
7.7
19
44
D06AX01
ATC
fusidic acid; topical
2.0
7.7
88
468
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.3
7.6
58
263
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.5
7.6
46
188
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
7.6
97
536
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
25.2
7.6
10
*
SPAT1229
SPAT
Assessment of need for aid
2.1
7.6
70
344
EKA10
NOMESCO Finland
iopsy of buccal mucosa
3.4
7.6
26
77
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
4.3
7.5
19
45
ZX120
NOMESCO Finland
Intravenous
2.0
7.5
86
458
TQW99
NOMESCO Finland
Other minor procedure on skin
2.5
7.5
48
202
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
7.5
92
502
L84
ICD-10 Finland
Corns and callosities
3.2
7.5
29
93
SPF40
NOMESCO Finland
Removal and reattachment of crown or small bridge
4.0
7.5
21
54
L51.9
ICD-10 Finland
Erythema multiforme, unspecified
13.5
7.4
12
9
M05BB03
ATC
alendronic acid and colecalciferol; oral
3.1
7.4
30
99
J01DC02
ATC
cefuroxime; systemic
2.3
7.4
53
235
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.0
7.3
32
110
N16.4*M32.1
ICD-10 Finland
Renal tubulo-interstitial disorders in systemic lupus erythematosus
+∞
7.3
7
*
L98.64
ICD-10 Finland
Benign lymphocyte infiltration into the skin [Jessner-Kanof]
+∞
7.3
7
*
G73.7*M32.1
ICD-10 Finland
Myopathy in systemic lupus erythematosus
+∞
7.3
7
*
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
7.3
105
603
N02AA05
ATC
oxycodone; systemic
1.7
7.2
149
948
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
7.2
34
122
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
7.2
109
635
R13
ICD-10 Finland
Dysphagia
2.1
7.2
66
324
D07BC01
ATC
betamethasone and antiseptics; topical
1.8
7.2
103
591
M35.8
ICD-10 Finland
Other specified systemic involvement of connective tissue
20.2
7.1
10
5
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
5.7
7.1
19
34
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
2.3
7.1
50
220
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
8.9
7.1
14
16
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.1
7.1
28
91
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.4
7.1
46
195
L21.9
ICD-10 Finland
Seborrhoeic dermatitis, unspecified
3.9
7.0
20
52
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.8
7.0
35
130
N03AX14
ATC
levetiracetam; systemic
3.1
7.0
29
97
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.2
7.0
60
287
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
7.0
135
845
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.6
6.9
38
148
SCA02
NOMESCO Finland
Preventive oral health care
1.9
6.9
91
507
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
6.9
126
775
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
6.9
306
2320
S18
ICPC
Laceration/cut
1.5
6.9
378
2987
L43.0
ICD-10 Finland
Hypertrophic lichen planus
8.3
6.8
14
17
A01AB09
ATC
miconazole; local oral
1.9
6.8
83
451
C08CA02
ATC
felodipine; oral
1.9
6.8
82
444
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
11.0
6.8
12
11
Z2221
NOMESCO Finland
Medical doctor
1.5
6.8
235
1691
I73.0
ICD-10 Finland
Raynaud syndrome
3.7
6.8
21
58
S88
ICPC
Dermatitis contact/allergic
3.3
6.7
24
73
N07BA03
ATC
varenicline; oral
2.4
6.7
47
206
M05BX04
ATC
denosumab; parenteral
2.1
6.7
62
305
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
22.7
6.7
9
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
6.7
62
306
R59.1
ICD-10 Finland
Generalized enlarged lymph nodes
4.1
6.6
18
45
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
6.6
67
341
127
Kela drug reimbursment
Transplant complication
6.0
6.6
17
29
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
6.6
88
493
M05BA07
ATC
risedronic acid; oral
2.6
6.6
37
146
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
4.2
6.6
17
41
Z94.0
ICD-10 Finland
Kidney transplant status
8.8
6.6
13
15
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.1
6.5
27
90
A02BA02
ATC
ranitidine; systemic
1.6
6.5
174
1180
J01MA02
ATC
ciprofloxacin; systemic
1.5
6.5
310
2378
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
6.5
242
1768
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
3.3
6.5
24
75
L30.0
ICD-10 Finland
Nummular dermatitis
2.7
6.5
34
130
XQ841
NOMESCO Finland
Examination of dermatosis with microscope
70.3
6.4
7
*
S29
ICPC
Skin symptom/complaint other
1.6
6.4
159
1059
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
2.5
6.4
40
167
N02BE01
ATC
paracetamol; systemic, rectal
1.7
6.3
793
7301
SPAT1263
SPAT
Sampling
1.4
6.2
352
2781
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.4
6.2
42
181
R06.0
ICD-10 Finland
Dyspnoea
1.5
6.2
226
1639
L57.0
ICD-10 Finland
Actinic keratosis
1.8
6.2
86
488
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
6.2
179
1237
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.2
194
1365
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.8
6.1
97
573
L30.3
ICD-10 Finland
Infective dermatitis
2.6
6.1
34
134
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
381
216
29.67
307.65
3.9
1.5
1.08
1.20
g/l
6.07
374
204
285
197
20.63
307.65
2.0
1.2
15.71
2.58
u/ml
1.15
62
23
382
209
30.83
307.65
4.0
1.5
0.20
0.23
g/l
6.47
368
198
314
246
18.98
307.65
4.3
1.6
—
—
—
0
0
289
208
19.91
307.65
2.0
1.2
61.11
38.59
u/ml
—
61
9
286
200
20.42
307.65
2.0
1.2
7.07
10.92
u/ml
0.28
98
33
341
275
19.26
307.65
1.8
1.3
2.66
1.32
u/ml
0.42
21
23
241
156
20.67
289.64
2.0
1.2
56.61
30.10
u/ml
0.84
93
11
235
156
19.98
278.48
1.8
1.2
2.94
8.44
u/ml
0.39
33
12
165
93
21.46
209.56
1.8
1.3
51.45
74.22
u/ml
—
13
5
647
3473
4.00
81.67
11.0
5.5
2.65
2.76
%
0.68
627
3240
650
3529
3.96
79.95
10.7
5.4
56.74
56.99
%
0.21
634
3304
655
3579
3.98
79.67
11.1
5.6
28.39
28.21
%
0.16
637
3353
727
4352
4.36
75.15
13.7
8.8
3.66
4.05
e9/l
6.07
693
3815
68
62
11.77
64.82
1.7
1.1
45.12
89.00
u/ml
—
16
8
67
105
6.81
41.45
1.4
1.1
1.65
1.70
u/ml
0.07
34
30
51
59
9.10
40.85
1.3
1.2
—
—
—
0
0
51
59
9.10
40.85
1.3
1.2
—
—
—
0
0
51
60
8.95
40.31
1.3
1.2
—
—
—
0
0
51
60
8.95
40.31
1.3
1.2
—
—
—
0
0
51
60
8.95
40.31
1.3
1.2
—
—
—
0
0
764
5672
3.19
37.75
7.8
4.0
14.58
12.27
mm/h
4.48
740
5230
44
47
9.79
37.37
1.2
1.2
—
—
—
0
0
156
529
3.35
37.00
3.1
2.9
11.51
10.69
g/l
1.36
149
484
62
104
6.33
35.87
1.4
1.2
3.18
3.41
u/ml
0.11
33
44
48
66
7.62
33.34
2.4
2.1
—
—
—
0
0
38
39
10.13
33.17
1.2
1.1
1.15
1.06
ratio
0.49
16
15
298
1530
2.41
31.51
3.6
2.3
5.45
7.31
e6/l
1.25
270
1379
385
2210
2.29
31.38
2.5
2.0
185.69
213.79
u/l
0.19
363
2085
766
5906
2.90
31.14
11.0
7.0
75.72
77.87
u/l
0.83
743
5521
123
434
3.12
26.94
1.7
1.9
1.39
1.56
g/l
0.38
112
396
536
3715
2.08
25.03
7.0
4.9
0.00
0.00
estimate
0.50
137
685
534
3699
2.08
24.94
5.3
3.7
0.00
0.00
estimate
0.74
142
735
412
2606
2.06
24.58
5.4
3.4
124.98
107.66
e6/l
0.12
325
1818
537
3749
2.06
24.28
5.4
3.7
0.00
0.00
estimate
0.50
137
673
362
2203
2.07
23.81
4.7
2.9
23.31
85.81
e6/l
1.32
307
1683
474
3182
2.02
23.69
5.6
4.3
35.21
35.66
g/l
0.92
449
2968
335
2008
2.06
22.73
4.6
2.8
0.44
0.49
e6/l
0.15
283
1502
76
225
3.59
21.95
1.6
1.6
395.00
154.00
titre
—
8
10
471
3259
1.93
20.49
2.9
2.2
79.94
78.13
nmol/l
0.69
446
2911
149
690
2.39
18.90
1.9
2.0
359.43
372.27
nmol/l
0.28
133
630
55
145
3.97
18.74
3.6
3.2
3.74
4.17
e9/l
0.68
55
145
56
150
3.91
18.67
3.9
3.4
59.11
57.61
%
0.34
56
150
30
47
6.57
18.46
1.9
1.4
4.96
7.44
u/l
0.78
25
37
239
1359
2.03
18.06
1.4
1.3
46.60
35.07
iu/ml
0.69
92
465
79
275
3.05
17.55
2.1
2.1
3.58
3.63
g/l
0.10
72
251
79
276
3.04
17.44
2.1
2.1
—
—
—
0
0
79
276
3.04
17.44
2.1
2.1
7.28
7.50
g/l
0.49
72
251
155
770
2.22
16.55
3.3
3.9
241.52
248.31
u/l
0.20
146
729
504
3720
1.80
16.42
7.6
6.0
1.22
1.22
mmol/l
0.78
415
3149
128
590
2.36
16.30
2.2
3.0
67.52
67.27
g/l
0.14
117
535
74
259
3.02
16.28
2.1
2.2
2.72
2.99
g/l
1.65
67
234
630
5024
1.83
15.30
5.7
4.4
977.33
3340.77
e6/l
0.88
12
81
72
258
2.94
15.19
2.1
2.1
10.98
10.36
g/l
0.50
65
232
310
2021
1.81
15.01
5.8
4.0
0.00
0.01
estimate
0.88
136
673
64
217
3.10
14.87
1.6
1.6
191.05
0.09
iu/ml
0.47
11
39
465
3414
1.74
14.87
6.3
5.2
1.22
1.22
mmol/l
0.96
438
3094
51
153
3.47
14.43
1.2
1.6
—
—
—
0
0
243
1492
1.86
14.17
1.6
1.5
2.66
2.38
g/l
1.16
157
884
179
999
1.99
13.89
2.7
2.2
2.28
2.36
g/l
1.09
163
923
65
238
2.86
13.19
2.2
2.5
0.09
1.04
g/l
2.66
55
209
168
933
1.98
13.17
2.9
2.3
23.43
22.78
%
0.27
146
803
22
36
6.24
12.98
1.3
1.6
17.40
23.50
u/ml
—
5
6
145
777
2.03
12.53
3.3
2.5
1.64
1.82
%
1.51
134
695
187
1101
1.88
12.25
2.8
2.2
13.11
13.17
umol/l
0.04
173
1023
211
1301
1.81
11.88
1.3
1.3
14.38
13.95
u/ml
0.03
90
498
60
223
2.81
11.86
2.3
2.1
37.99
38.21
g/l
0.11
53
198
52
180
3.00
11.67
1.7
1.6
—
—
—
0
0
57
210
2.83
11.45
2.4
2.1
0.00
0.03
g/l
0.50
52
195
361
2611
1.64
11.21
3.5
3.3
2.34
2.36
mmol/l
1.14
319
2289
21
21
10.21
11.04
1.2
1.0
8.27
8.82
ug/l
0.24
21
21
836
7568
2.32
11.02
21.8
12.9
20.33
22.60
mg/l
1.18
702
5901
195
1206
1.79
10.77
3.7
2.5
0.85
1.22
e6/l
1.56
133
649
53
195
2.82
10.68
2.5
2.2
0.00
0.00
g/l
-0.00
48
183
387
2874
1.60
10.63
5.8
3.8
—
—
—
0
0
499
3940
1.59
10.54
6.5
5.9
9.59
10.80
umol/l
2.13
480
3737
53
197
2.80
10.48
2.5
2.2
0.00
0.00
g/l
-0.00
48
184
436
3339
1.59
10.46
12.8
13.1
1.13
1.22
inr
2.03
155
956
69
294
2.46
10.39
2.3
2.0
1.49
1.56
g/l
0.23
57
258
155
911
1.85
10.07
6.1
4.3
1.06
1.03
mmol/l
0.56
148
822
22
49
4.58
9.34
1.1
1.1
567.50
76.67
titre
—
8
9
698
6093
1.63
8.65
4.6
4.1
14.74
14.77
pmol/l
0.13
648
5518
98
529
1.96
8.21
7.2
6.2
10.39
9.30
mmol/l
0.67
92
499
324
2419
1.53
8.13
3.9
3.1
31.66
30.72
u/l
0.28
307
2304
175
1142
1.66
7.76
1.9
1.7
—
—
—
0
0
243
1719
1.56
7.72
1.3
1.2
3.11
1.58
u/ml
0.39
63
435
207
1417
1.60
7.55
3.3
2.8
2.46
2.46
mmol/l
0.06
179
1248
28
89
3.21
7.31
2.3
2.2
—
717.40
—
0
5
309
2338
1.49
7.06
2.7
2.4
60.27
61.95
u/l
0.17
286
2137
17
39
4.42
6.98
2.2
1.9
—
—
—
0
0
28
92
3.11
6.94
1.4
1.4
—
—
—
0
0
251
1832
1.51
6.79
2.6
2.1
3.14
3.05
mg/l
0.21
217
1549
14
18
7.88
6.63
1.0
1.1
—
—
—
0
0
409
3303
1.43
6.51
3.1
2.7
125.73
109.93
ug/l
1.13
376
3036
194
1351
1.55
6.48
4.4
3.7
383.48
333.17
ng/l
0.13
152
1018
167
1124
1.60
6.46
4.1
2.7
3.03
3.48
e6/l
0.30
107
574
121
752
1.70
6.40
4.5
3.2
—
—
—
0
0
171
1169
1.57
6.18
3.7
2.9
0.81
0.82
mmol/l
0.22
158
1098
276
2087
1.46
6.17
3.0
2.9
1140.87
1076.49
ng/l
0.13
241
1753
46
211
2.24
5.94
1.8
2.7
—
—
—
0
0
506
4289
1.41
5.90
4.9
4.3
6.31
6.62
mmol/l
3.74
485
4000
248
1853
1.47
5.85
4.3
3.4
96.06
93.42
%
0.97
241
1801
87
511
1.78
5.62
1.8
1.5
—
—
—
0
0
33
134
2.52
5.59
1.2
1.4
—
—
—
0
0
223
1646
1.47
5.57
5.5
4.0
1.02
1.02
kg/l
0.03
24
239
93
563
1.73
5.41
2.6
2.8
232.24
195.16
ng/l
0.26
83
520
19
58
3.32
5.33
1.3
1.3
—
—
titre
—
0
0
15
40
3.80
5.10
1.1
1.2
—
—
—
0
0
188
1366
1.47
5.04
2.0
1.7
1225.86
1194.87
nmol/l
0.18
148
1007
852
8091
1.86
4.92
18.1
10.0
25.46
24.95
u/l
0.43
844
7788
16
46
3.52
4.91
1.4
1.2
—
—
—
0
0
271
2119
1.40
4.85
4.3
3.1
1361.61
302.41
mg/l
1.17
172
1270
136
931
1.54
4.84
2.4
2.2
134.48
124.69
ug/g
0.14
113
718
224
1696
1.43
4.81
1.8
1.7
0.96
1.08
mg/l
0.47
187
1290
91
572
1.66
4.62
2.6
2.4
4.99
7.48
ug/l
1.41
76
502
14
31
4.57
4.57
1.1
1.6
—
—
—
0
0
14
31
4.57
4.57
1.1
1.6
—
—
—
0
0
718
6588
1.43
4.55
26.1
15.8
14.97
14.93
%
0.06
712
6466
77
471
1.69
4.34
1.3
1.2
167.17
217.74
u/ml
0.32
71
429
826
7826
1.61
4.17
21.0
14.7
138.90
139.67
mmol/l
10.87
811
7602
828
7850
1.62
4.16
21.2
14.8
3.93
3.95
mmol/l
1.14
812
7611
116
793
1.53
4.16
1.7
1.7
—
—
—
0
0
769
7178
1.47
4.15
5.6
4.9
2.01
1.88
mu/l
0.58
716
6539
67
402
1.72
4.06
3.6
3.3
1.19
1.82
mmol/l
0.63
48
300
35
169
2.11
4.06
1.4
1.8
4685.19
15440.01
e6/l
1.46
27
130
238
1871
1.37
4.02
2.8
2.4
6085.81
6055.89
umol/l
0.00
212
1630
95
631
1.56
3.88
5.1
3.5
1.24
1.23
mmol/l
0.18
90
541
10
19
5.31
3.83
2.1
2.2
—
—
—
0
0
28
127
2.24
3.80
1.2
1.3
277.50
227.67
u/ml
0.44
20
76
20
78
2.60
3.73
1.2
1.6
—
—
—
0
0
30
142
2.15
3.68
2.7
2.4
15.96
16.02
%
0.03
17
68
276
2246
1.33
3.67
4.4
3.0
6.97
7.08
mmol/l
0.16
239
1887
29
136
2.17
3.64
1.2
1.2
—
—
—
0
0
14
40
3.54
3.61
1.3
1.3
16.99
24.52
umol/l
0.51
14
40
114
802
1.48
3.57
1.8
1.7
—
—
—
0
0
361
3058
1.30
3.57
2.1
1.9
94.12
96.05
pmol/l
0.37
179
1530
26
118
2.24
3.54
1.3
1.3
—
—
—
0
0
223
1769
1.35
3.51
2.3
2.1
—
—
—
0
0
90
605
1.54
3.50
4.9
3.2
84.26
77.23
ng/l
0.40
83
527
272
2230
1.31
3.39
5.3
3.6
15.94
8.27
mg/mmol
1.07
172
1319
30
147
2.08
3.39
2.4
2.1
129.45
129.75
g/l
0.02
20
108
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
36
189
1.94
3.38
2.5
2.5
0.24
0.38
u/ml
2.52
15
103
41
225
1.86
3.38
2.1
4.1
35.55
76.51
mg/l
0.79
32
183
41
225
1.86
3.38
2.2
4.1
47.02
74.53
mg/l
0.46
31
183
13
42
3.13
3.38
1.4
1.5
—
—
—
0
0
9
18
5.04
3.37
1.0
1.1
—
—
—
0
0
21
89
2.39
3.34
1.2
1.1
—
—
—
0
0
330
2791
1.29
3.23
4.1
3.5
257.66
45.75
ng/l
0.47
235
1884
549
4946
1.28
3.21
3.6
3.0
53.13
46.78
u/l
0.91
518
4580
29
144
2.05
3.18
4.2
3.2
61.61
2507.29
u/ml
0.77
23
134
115
830
1.44
3.17
2.9
2.5
7.21
7.30
umol/l
0.02
100
710
11
30
3.70
3.09
1.9
1.6
68.50
52.24
ug/l
0.26
11
30
13
41
3.20
3.06
1.4
1.5
—
—
—
0
0
220
1775
1.32
3.05
1.7
1.5
20.38
21.39
nmol/l
0.44
183
1497
13
45
2.92
3.03
1.0
1.1
—
10.56
—
0
14
5
5
10.04
2.98
1.4
1.0
—
—
—
0
0
12
37
3.27
2.94
1.1
1.2
—
—
—
0
0
762
7216
1.35
2.78
20.3
12.0
82.92
80.93
ml/min/173m2
1.71
658
5891
18
78
2.33
2.76
5.6
5.6
6.86
7.20
mmol/l
0.16
13
64
13
48
2.73
2.72
1.2
1.3
1.78
1.95
mmol/l
0.67
13
48
20
92
2.20
2.68
1.8
1.6
54.67
62.06
%
0.27
12
64
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
43
2.81
2.65
1.0
1.1
—
—
—
0
0
7
15
4.69
2.60
1.4
2.0
—
—
—
0
0
17
74
2.32
2.59
1.2
1.1
—
—
—
0
0
43
261
1.68
2.59
1.9
1.6
—
—
—
0
0
31
171
1.84
2.57
1.2
1.5
—
—
—
0
0
33
186
1.80
2.56
1.4
1.2
413.64
491.91
mg/l
0.93
33
174
15
62
2.44
2.55
1.3
1.7
—
—
—
0
0
45
278
1.65
2.54
2.0
1.7
—
—
—
0
0
27
143
1.92
2.53
1.3
1.3
—
—
—
0
0
27
143
1.92
2.53
1.3
1.3
—
—
—
0
0
34
195
1.77
2.50
1.4
1.4
—
—
—
0
0
13
51
2.57
2.45
1.5
1.4
—
—
—
0
0
6
12
5.03
2.40
1.0
1.0
—
—
—
0
0
13
52
2.52
2.36
1.0
1.0
—
—
—
0
0
25
133
1.90
2.33
1.3
1.4
—
—
—
0
0
20
98
2.06
2.33
1.4
1.4
—
—
—
0
0
15
65
2.33
2.32
1.5
2.3
—
—
—
0
0
59
401
1.50
2.25
1.7
1.6
—
—
—
0
0
38
233
1.66
2.23
2.1
1.6
—
—
—
0
0
36
218
1.68
2.22
1.3
1.5
297.43
297.45
ug/g
0.00
16
125
21
107
1.99
2.22
1.1
1.1
—
—
—
0
0
5
9
5.58
2.21
1.2
1.6
55.20
95.89
ng/l
—
5
9
11
41
2.70
2.21
1.0
1.1
—
—
—
0
0
12
48
2.52
2.19
1.0
1.2
—
—
—
0
0
396
3536
1.21
2.17
2.7
2.4
—
—
—
0
0
104
790
1.36
2.17
5.5
6.8
12.69
12.29
kpa
0.37
98
751
104
790
1.36
2.17
5.5
6.8
4.97
5.09
kpa
0.73
98
750
6
14
4.31
2.15
1.0
1.1
—
—
—
0
0
31
182
1.73
2.14
1.2
1.2
—
—
—
0
0
12
49
2.47
2.11
1.0
1.2
—
—
—
0
0
29
168
1.75
2.10
1.2
1.5
—
—
—
0
0
81
595
1.40
2.08
3.4
2.4
54.52
66.66
ml/min/173m2
2.04
31
248
15
69
2.19
2.05
3.8
1.6
33.24
21.24
ug/l
0.32
15
69
103
789
1.34
2.05
5.6
6.8
0.34
1.29
mmol/l
1.20
80
630
6
15
4.02
2.04
1.2
1.3
—
—
—
0
0
16
76
2.13
2.03
1.3
1.1
—
—
—
0
0
193
1613
1.25
1.98
1.7
1.7
71605396.38
19654052.22
pmol/l
0.32
162
1328
510
4692
1.20
1.97
3.1
3.0
—
—
—
0
0
27
157
1.74
1.94
1.2
1.3
—
—
—
0
0
19
99
1.94
1.91
1.3
1.1
117.31
118.56
%
0.06
13
90
11
46
2.41
1.85
1.4
1.0
—
—
—
0
0
863
8427
1.49
1.85
32.1
19.5
39.35
39.82
%
1.63
818
7876
67
488
1.40
1.83
2.6
3.3
4.27
4.57
pmol/l
2.04
52
428
863
8429
1.48
1.82
32.2
19.5
252.60
255.63
e9/l
0.70
855
8200
8
29
2.77
1.79
1.1
1.3
—
—
—
0
0
8
29
2.77
1.79
1.0
1.1
1266.75
1811.48
miu/ml
—
8
29
8
29
2.77
1.79
1.1
1.0
—
—
—
0
0
30
185
1.64
1.77
2.1
2.2
168.52
179.46
%
0.26
25
178
863
8433
1.47
1.77
32.2
19.5
4.35
4.45
e12/l
9.02
853
8184
20
110
1.84
1.74
1.4
1.4
—
—
—
0
0
21
118
1.80
1.71
1.3
1.4
—
—
—
0
0
22
126
1.76
1.69
1.2
1.6
—
—
—
0
0
6
19
3.17
1.66
1.0
1.1
—
—
—
0
0
59
429
1.40
1.65
1.3
1.5
—
—
—
0
0
10
41
2.45
1.64
1.1
1.2
—
—
—
0
0
14
70
2.02
1.59
1.2
1.2
—
—
—
0
0
19
106
1.81
1.59
1.2
1.5
—
—
—
0
0
6
20
3.01
1.58
1.0
1.1
—
—
—
0
0
13
64
2.05
1.54
1.4
1.3
—
—
—
0
0
6
21
2.87
1.50
1.0
1.2
—
—
—
0
0
7
28
2.51
1.45
1.1
1.1
83.13
150.66
iu/ml
—
7
28
6
22
2.74
1.43
1.0
1.1
—
—
—
0
0
235
2071
1.18
1.40
1.8
1.6
1.29
1.36
mmol/l
0.73
189
1745
7
29
2.42
1.39
1.1
1.1
—
—
—
0
0
7
29
2.42
1.39
2.3
1.6
—
—
—
0
0
5
17
2.95
1.36
1.0
1.0
—
—
—
0
0
5
17
2.95
1.36
1.0
1.3
—
—
—
0
0
11
54
2.05
1.33
1.5
1.7
16.34
18.74
nmol/l
0.39
11
49
78
615
1.29
1.33
3.6
3.0
1.30
2.08
mmol/l
1.14
63
497
9
173
0.52
1.30
1.7
1.5
—
—
—
0
0
10
48
2.10
1.28
1.6
1.8
—
—
—
0
0
25
162
1.56
1.27
2.2
2.3
105.99
82.48
ug/min
0.12
13
94
43
312
1.40
1.26
1.9
1.4
—
—
—
0
0
48
639
0.74
1.26
1.6
1.7
—
—
—
0
0
8
159
0.50
1.25
1.6
1.4
—
—
—
0
0
8
159
0.50
1.25
1.6
1.4
—
—
—
0
0
8
159
0.50
1.25
1.6
1.4
—
—
—
0
0
8
159
0.50
1.25
1.6
1.4
—
—
—
0
0
37
262
1.43
1.24
4.5
3.6
24.21
24.86
mmol/l
0.78
37
245
6
25
2.41
1.24
3.2
4.2
—
—
—
0
0
18
288
0.62
1.22
1.5
1.5
—
—
—
0
0
19
294
0.64
1.13
2.2
3.3
21.36
4635.21
u/ml
0.77
14
255
78
630
1.26
1.13
5.5
5.6
1.24
1.34
mmol/l
0.49
78
612
153
1325
1.19
1.12
1.4
1.5
—
—
—
0
0
77
622
1.26
1.11
3.7
3.0
5.70
5.80
kpa
0.44
72
603
28
193
1.47
1.10
1.3
1.3
—
—
—
0
0
5
21
2.39
1.09
1.0
1.1
—
—
—
0
0
17
106
1.62
1.03
1.4
1.1
—
—
—
0
0
15
91
1.66
1.01
1.4
1.3
—
—
—
0
0
11
61
1.81
0.98
4.1
2.1
—
—
—
0
0
20
132
1.53
0.97
1.2
1.6
—
—
—
0
0
17
108
1.59
0.97
1.1
1.1
—
—
—
0
0
27
191
1.43
0.95
1.2
1.1
—
—
—
0
0
11
62
1.78
0.94
2.3
1.4
—
—
—
0
0
15
93
1.62
0.94
1.4
1.3
—
—
—
0
0
15
93
1.62
0.94
1.4
1.3
—
—
—
0
0
69
564
1.24
0.93
1.4
1.2
158.58
149.25
iu/ml
0.06
34
215
6
29
2.08
0.89
1.0
1.3
—
—
—
0
0
16
241
0.66
0.88
2.3
1.7
—
—
—
0
0
17
112
1.53
0.85
1.1
1.4
—
—
—
0
0
17
112
1.53
0.85
1.1
1.4
—
—
—
0
0
13
80
1.63
0.85
1.1
1.3
—
—
—
0
0
13
80
1.63
0.85
1.1
1.3
—
—
—
0
0
6
32
1.88
0.82
1.0
1.1
—
—
—
0
0
10
161
0.62
0.75
1.1
1.7
1.14
0.84
nmol/l
—
10
127
7
38
1.85
0.73
1.3
1.0
—
—
—
0
0
22
159
1.39
0.73
5.7
3.7
30.54
26.59
mg/l
0.17
13
94
5
25
2.01
0.72
1.0
1.2
—
—
—
0
0
7
39
1.80
0.72
1.4
1.5
—
—
—
0
0
7
40
1.76
0.71
5.0
3.0
—
—
—
0
0
26
197
1.33
0.66
1.5
1.2
—
—
—
0
0
66
772
0.84
0.65
3.1
2.9
0.56
0.72
ug/l
1.81
43
491
78
678
1.16
0.60
2.7
2.4
48.70
40.34
u/l
0.33
70
571
60
511
1.19
0.59
2.7
2.5
4.52
4.50
kpa
0.03
55
493
82
719
1.15
0.58
1.7
2.0
—
—
—
0
0
6
35
1.72
0.57
1.0
1.1
—
—
—
0
0
106
949
1.13
0.56
7.6
6.4
—
—
—
0
0
31
248
1.26
0.56
3.7
3.8
1.59
1.27
mmol/l
0.49
31
242
9
60
1.50
0.54
1.0
1.0
—
—
—
0
0
11
74
1.49
0.53
1.0
1.5
—
—
—
0
0
10
66
1.52
0.52
1.3
1.1
—
—
—
0
0
29
236
1.24
0.47
1.2
1.2
—
—
—
0
0
5
81
0.62
0.46
1.2
1.2
—
—
—
0
0
73
649
1.14
0.45
1.6
1.9
—
—
—
0
0
7
50
1.40
0.45
1.4
1.5
0.88
1.26
promille
—
7
40
757
7458
1.09
0.42
4.8
4.5
5.69
5.90
mmol/l
4.71
698
6776
713
7010
1.08
0.41
5.9
5.5
38.83
39.56
mmol/mol
1.52
656
6466
36
421
0.85
0.40
1.5
1.3
—
—
—
0
0
9
67
1.35
0.38
1.0
1.5
—
—
—
0
0
12
90
1.34
0.36
1.4
1.3
—
—
—
0
0
12
90
1.34
0.36
1.4
1.3
—
—
—
0
0
27
227
1.20
0.35
1.2
1.1
—
—
—
0
0
6
44
1.37
0.34
1.2
1.4
5.53
6.29
mmol/l
—
6
44
734
7240
1.07
0.34
4.2
3.9
1.23
1.28
mmol/l
1.08
671
6598
12
91
1.32
0.34
1.4
1.3
—
—
—
0
0
28
238
1.18
0.32
3.0
2.2
17022.43
2662.15
u/l
—
7
100
759
7501
1.07
0.31
4.6
4.3
1.49
1.53
mmol/l
1.85
688
6890
19
156
1.22
0.31
3.7
7.7
105.84
105.47
mmol/l
0.17
19
140
14
112
1.25
0.28
1.2
1.1
0.28
1.90
u/ml
—
6
54
157
1498
1.06
0.24
1.7
1.4
—
—
—
0
0
20
172
1.17
0.22
2.7
1.7
—
—
—
0
0
5
41
1.22
0.22
1.4
1.2
—
—
—
0
0
5
41
1.22
0.22
1.4
1.2
—
—
—
0
0
26
229
1.14
0.22
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
8
104
0.77
0.21
1.1
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
761
7549
1.05
0.19
4.7
4.4
4.57
4.77
mmol/l
6.42
696
6970
18
205
0.88
0.17
1.9
1.8
7.88
5.29
iu/l
—
7
70
138
1332
1.04
0.15
4.7
4.6
1.90
2.33
ug/l
0.68
123
1185
13
112
1.16
0.14
1.5
1.6
—
—
—
0
0
11
94
1.17
0.13
2.1
2.5
23.80
20.17
mg/l
—
5
26
12
138
0.87
0.13
1.4
1.5
—
—
—
0
0
109
1056
1.04
0.11
4.5
4.2
21.86
20.63
%
0.31
44
482
83
801
1.04
0.10
3.7
4.0
8.14
27.41
ug/l
1.03
70
656
33
312
1.06
0.08
1.5
1.6
—
—
—
0
0
79
814
0.97
0.08
1.8
1.7
1.59
1.43
%
1.53
69
719
95
975
0.97
0.07
4.3
4.4
34.00
32.57
%
0.59
70
641
10
89
1.12
0.07
1.0
1.0
—
—
—
0
0
9
102
0.88
0.06
1.3
1.5
—
—
—
0
0
771
7687
1.02
0.06
5.2
4.9
2.67
2.81
mmol/l
4.45
705
7061
12
131
0.91
0.05
1.6
1.7
—
—
—
0
0
39
405
0.96
0.05
1.6
1.7
—
—
—
0
0
22
231
0.95
0.04
1.2
1.3
244.80
261.67
miu/ml
—
10
108
28
269
1.04
0.04
4.7
5.8
1.73
1.55
%
0.84
28
251
19
180
1.06
0.04
4.0
3.9
31.68
42.56
u/ml
0.29
19
174
13
122
1.07
0.02
1.7
1.7
43.15
43.71
nmol/l
0.02
13
115
29
283
1.03
0.01
1.4
1.4
—
—
—
0
0
11
108
1.02
0.00
3.9
4.9
406.60
368.14
umol/l
—
6
92
12
123
0.98
0.00
1.4
1.0
—
13.49
—
0
9
40
395
1.01
0.00
1.1
1.0
—
—
—
0
0
5
49
1.02
0.00
1.4
1.7
12.92
11.49
umol/l
—
5
44
6
65
0.92
-0.00
1.2
1.5
—
—
—
0
0
6
65
0.92
-0.00
1.2
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
7.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
7.57
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
98.60
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
59
0.85
-0.00
2.2
1.6
0.79
1.02
g/l
—
5
59
6
65
0.92
-0.00
1.2
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_LUPUS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_LUPUS | 1.429 [1.27, 1.61] | < 0.001 |
| Birth year | 0.993 [0.99, 1.0] | 0.127 |
During the follow-up period (1.1.1998 — 31.12.2019), 690 out of 3420 females with L12_LUPUS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_LUPUS | 1.68 [1.43, 1.98] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 248 out of 1146 males with L12_LUPUS died.
Mortality risk
Mortality risk for people of age
years, who have L12_LUPUS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.121% | 0.312% |
| 5 | 0.794% | 1.697% |
| 10 | 2.072% | 4.409% |
| 15 | 3.835% | 8.15% |
| 20 | 6.609% | 13.991% |
Relationships between endpoints
↥Index endpoint: L12_LUPUS – Cutaneous lupus erythematosus
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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