No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
122 |
4. Check minimum number of eventsNone |
122 |
5. Include endpointsNone |
122 |
6. Filter based on genotype QC (FinnGen only) |
122 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Similar endpoints
↥List of similar endpoints to
Meretoja disease
based on the number of shared cases.
Similar with more cases:
- Amyloidosis, other/unspecified
- Amyloidosis
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 122 | 67 | 55 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.03 |
| Median age at first event (years) | 57.95 | 55.78 | 60.59 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 122
- Matched controls
- 1220
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E85.80
ICD-10 Finland
Meretoja sick
+∞
145.8
109
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
91.5
76
*
H16.0
ICD-10 Finland
Corneal ulcer
25.1
61.7
51
34
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
351.7
47.6
45
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
19.7
35.9
110
387
H02.3
ICD-10 Finland
Blepharochalasis
13.9
35.9
39
40
ZXA10
NOMESCO Finland
Bilateral
8.0
29.9
62
139
XCW99
NOMESCO Finland
Other investigative procedure of eye
8.9
27.0
42
68
QAJ10
NOMESCO Finland
Browlift
+∞
23.7
22
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
+∞
23.7
22
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
147.9
23.5
24
*
H04.10
ICD-10 Finland
Dry eye syndrome
7.4
23.0
43
84
Z31.5
ICD-10 Finland
Genetic counselling
10.7
21.5
26
30
H19.8
ICD-10 Finland
Other disorders of sclera and cornea in diseases classified elsewhere
+∞
21.5
20
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
+∞
20.4
19
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
6.6
20.3
42
90
H02.2
ICD-10 Finland
Lagophthalmos
236.9
20.2
20
*
WX002
NOMESCO Finland
Sedation and analgesia
5.4
18.2
52
148
ACC51
NOMESCO Finland
Release of median nerve
7.4
16.4
27
45
Z3229
NOMESCO Finland
Other healthcare associate professional
6.8
16.4
30
56
CG2S4
NOMESCO Finland
Photography of cornea
+∞
16.0
15
*
N08.4*E85.80
ICD-10 Finland
Glomerular disease in Meretoja's patients
+∞
16.0
15
*
S01XA18
ATC
ciclosporin; ophthalmic
91.4
15.0
16
*
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
+∞
14.9
14
*
H02.1
ICD-10 Finland
Ectropion of eyelid
29.8
13.8
18
7
E85.0
ICD-10 Finland
Non-neuropathic heredofamilial amyloidosis
+∞
13.8
13
*
E85.89
ICD-10 Finland
Other amyloidosis
+∞
13.8
13
*
S01AD03
ATC
aciclovir; ophthalmic
13.3
13.8
24
22
XCK10
NOMESCO Finland
Photography of fundus of eye
5.4
13.3
31
72
R4120
NOMESCO Finland
Occupational therapy
6.7
13.0
23
41
H18.4
ICD-10 Finland
Corneal degeneration
+∞
12.7
12
*
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
12.7
12
*
CBH25
NOMESCO Finland
Tarsorrhaphy
+∞
12.7
12
*
E85.9
ICD-10 Finland
Amyloidosis, unspecified
+∞
12.7
12
*
E85.8
ICD-10 Finland
Other amyloidosis
+∞
12.7
12
*
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
18.9
12.1
18
11
G51.0
ICD-10 Finland
Bell palsy
26.0
11.9
16
7
H02.4
ICD-10 Finland
Ptosis of eyelid
12.4
11.8
21
20
H16.9
ICD-10 Finland
Keratitis, unspecified
28.2
11.4
15
6
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.6
11.1
32
88
ZXA05
NOMESCO Finland
Left side
3.7
11.0
52
204
CBN30
NOMESCO Finland
Shortening of canthal ligament
65.9
10.8
12
*
QAJ30
NOMESCO Finland
Other facelift
65.9
10.8
12
*
ZZC00
NOMESCO Finland
Graft of fascia
119.9
10.6
11
*
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
+∞
10.6
10
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
+∞
10.6
10
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.1
10.4
35
108
S01ED51
ATC
timolol, combinations; ophthalmic
5.5
10.2
22
47
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
44.0
10.2
12
*
CBF99
NOMESCO Finland
Other operation for ectropion
59.9
9.8
11
*
S01GX01
ATC
cromoglicic acid; ophthalmic
3.7
9.6
39
137
H25.1
ICD-10 Finland
Senile nuclear cataract
3.3
9.4
54
236
114
Kela drug reimbursment
Glaucoma
4.9
9.4
23
55
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.2
9.1
59
276
S01EE05
ATC
tafluprost; ophthalmic
12.1
9.1
16
15
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.1
8.9
28
82
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
18.0
8.8
13
8
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
8.1
8.7
19
27
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
14.2
8.6
14
11
S01BA01
ATC
dexamethasone; ophthalmic
12.0
8.6
15
14
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
+∞
8.4
8
*
E85.2
ICD-10 Finland
Heredofamilial amyloidosis, unspecified
+∞
8.4
8
*
CGD10
NOMESCO Finland
Laser keratoplasty for error of refraction
+∞
8.4
8
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
7.0
8.3
20
33
H40.0
ICD-10 Finland
Glaucoma suspect
4.4
8.2
23
61
ZXE10
NOMESCO Finland
More than one and less than three hours
2.9
7.8
63
327
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
9.9
7.8
15
17
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
8.6
7.7
16
21
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.5
7.5
20
51
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
17.1
7.4
11
7
EAB20
NOMESCO Finland
Plastic repair of lip
+∞
7.4
7
*
Z94.7
ICD-10 Finland
Corneal transplant status
+∞
7.4
7
*
QAJ15
NOMESCO Finland
Browlift using video-endoscope
+∞
7.4
7
*
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
+∞
7.4
7
*
ZXE00
NOMESCO Finland
One hour or less
2.8
7.0
64
349
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
7.0
36
144
E0000UV, ,
ATC
2.7
6.9
65
360
H18.8
ICD-10 Finland
Other specified disorders of cornea
42.5
6.8
8
*
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
8.6
6.8
14
18
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
6.9
6.7
16
26
S01AA01
ATC
chloramphenicol; ophthalmic
6.2
6.6
17
31
ZXD10
NOMESCO Finland
Scheduled procedure
2.7
6.6
62
341
S18
ICPC
Laceration/cut
2.6
6.4
71
421
A46
ICD-10 Finland
Erysipelas
3.3
6.3
28
102
CBN99
NOMESCO Finland
Other operation on eyelid for malposition
28.3
6.3
8
*
N08.4
ICD-10 Finland
Glomerular disorders in other endocrine, nutritional and metabolic diseases
+∞
6.3
6
*
QAJ35
NOMESCO Finland
Other correction of loose or redundant skin of head or neck
+∞
6.3
6
*
E85
ICD-10 Finland
Amyloidosis
+∞
6.3
6
*
H198, E858,
ICD-10 Finland
+∞
6.3
6
*
CD2S4
NOMESCO Finland
Photography of eye
+∞
6.3
6
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
5.8
6.3
17
33
WX110
NOMESCO Finland
Infiltration anesthesia
3.1
6.2
97
679
ZXA00
NOMESCO Finland
Right side
2.7
6.1
45
217
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
10
9
11.96
5.91
2.7
4.7
—
—
—
0
0
54
304
2.39
5.17
2.9
2.9
0.18
0.52
e6/l
1.64
44
226
55
313
2.38
5.13
5.5
3.8
38.81
7.06
mg/mmol
1.56
35
198
61
380
2.21
4.43
4.2
3.0
—
—
—
0
0
51
298
2.22
4.32
3.6
3.1
1551.53
1304.00
ng/l
0.19
45
249
33
163
2.40
4.10
2.2
2.9
5.45
3.16
e6/l
0.39
20
74
8
12
7.04
3.73
1.3
1.1
—
—
—
0
0
34
177
2.28
3.73
2.0
2.6
1.03
1.07
e6/l
0.04
21
87
17
65
2.88
3.47
4.6
5.1
23.82
25.31
mmol/l
0.76
17
65
64
438
1.97
3.34
4.5
4.0
33.60
35.87
g/l
2.06
56
416
23
111
2.32
2.97
3.5
3.5
—
—
—
0
0
12
39
3.30
2.87
2.3
1.4
—
—
—
0
0
14
55
2.75
2.72
1.2
1.3
—
—
—
0
0
62
446
1.79
2.57
6.8
5.5
1.22
1.21
mmol/l
0.23
56
411
11
43
2.71
2.14
1.5
2.2
1.32
1.56
g/l
0.60
11
36
36
231
1.79
2.12
2.2
2.0
—
—
—
0
0
54
399
1.63
1.87
3.3
2.5
160.98
111.28
ug/l
0.84
49
365
7
23
3.16
1.83
3.0
2.6
51.29
61.78
%
—
7
23
112
1013
2.29
1.76
16.6
13.6
21.99
24.32
mg/l
0.36
87
786
64
505
1.56
1.63
4.4
3.7
0.00
0.00
estimate
-0.00
19
117
53
402
1.56
1.59
2.8
2.3
72.33
77.06
nmol/l
0.66
48
356
64
508
1.55
1.56
5.4
5.0
0.00
0.00
estimate
-0.00
18
109
6
137
0.41
1.52
14.2
8.0
—
—
—
0
0
64
511
1.53
1.51
4.4
3.7
0.00
0.00
estimate
-0.00
18
105
59
466
1.52
1.44
11.5
12.1
1.14
1.25
inr
0.50
18
143
89
768
1.59
1.44
4.4
4.3
18.63
11.28
mm/h
2.50
83
706
11
53
2.18
1.43
2.2
1.4
—
—
—
0
0
62
497
1.50
1.40
7.9
6.2
1.23
1.21
mmol/l
0.82
46
417
6
23
2.69
1.38
1.5
1.5
—
—
—
0
0
51
394
1.51
1.37
2.5
1.8
107.50
94.99
pmol/l
0.54
24
186
40
294
1.54
1.35
1.9
1.6
1.27
1.33
mmol/l
0.24
33
240
71
593
1.47
1.27
8.2
9.9
4.18
4.15
e9/l
0.05
62
516
102
921
1.66
1.24
4.6
4.7
2.01
1.95
mu/l
0.20
93
833
5
19
2.70
1.23
1.6
1.2
—
—
—
0
0
15
87
1.83
1.21
2.1
3.2
51.50
62.06
ml/min/173m2
—
8
36
6
26
2.37
1.20
1.3
2.0
—
—
—
0
0
0
36
0.00
1.16
0.0
1.8
—
—
—
0
0
86
753
1.48
1.15
4.2
4.0
15.11
14.87
pmol/l
0.36
79
673
15
91
1.74
1.06
2.7
2.3
351.87
357.74
nmol/l
0.04
15
85
5
22
2.33
1.04
1.2
1.2
—
—
—
0
0
31
228
1.48
1.03
1.4
1.6
1.45
1.08
mg/l
0.43
22
183
0
31
0.00
0.98
0.0
1.9
—
—
—
0
0
113
1067
1.80
0.96
21.3
16.6
82.68
76.99
umol/l
1.40
113
1067
90
807
1.44
0.96
7.3
7.3
77.74
79.06
u/l
0.10
85
752
11
63
1.82
0.93
2.0
1.5
—
—
—
0
0
26
191
1.46
0.86
2.3
2.7
2.49
2.45
mmol/l
0.86
20
167
55
461
1.35
0.86
2.8
2.3
—
—
—
0
0
7
122
0.55
0.83
5.6
4.7
36.43
31.58
%
—
7
76
38
302
1.38
0.82
1.9
2.0
192.42
226.47
u/l
0.20
33
285
21
150
1.48
0.80
1.8
2.0
—
—
—
0
0
0
25
0.00
0.80
0.0
1.0
—
0.90
—
0
19
17
117
1.53
0.77
1.9
1.9
—
—
—
0
0
5
25
2.04
0.73
1.8
1.3
—
—
—
0
0
17
120
1.48
0.69
1.9
1.9
—
—
—
0
0
103
966
1.43
0.68
19.5
13.0
75.31
79.92
ml/min/173m2
1.42
94
802
23
175
1.39
0.64
1.9
1.7
1035.47
1341.68
nmol/l
0.83
17
134
42
351
1.30
0.64
3.1
3.4
2.33
2.36
mmol/l
0.67
36
308
101
948
1.38
0.62
5.2
5.8
37.66
40.11
mmol/mol
2.95
91
889
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
15
107
1.46
0.58
1.7
2.2
1.24
1.60
%
—
10
92
34
282
1.29
0.54
5.6
3.8
0.00
0.00
estimate
-0.00
18
107
115
1113
1.58
0.51
25.8
20.5
39.14
40.33
%
2.14
107
1063
5
31
1.64
0.43
1.4
2.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
234.10
—
0
16
5
34
1.49
0.41
2.2
1.5
—
—
—
0
0
10
73
1.40
0.36
2.2
2.5
18.06
13.11
nmol/l
—
10
67
102
981
1.24
0.33
5.4
4.8
5.92
5.97
mmol/l
0.14
92
906
24
203
1.23
0.33
3.4
2.8
0.87
0.77
ug/l
0.30
19
128
62
574
1.16
0.32
2.9
2.9
—
—
—
0
0
12
94
1.31
0.29
1.9
1.9
—
—
—
0
0
9
75
1.22
0.25
1.6
2.3
—
—
—
0
0
16
190
0.82
0.25
1.3
1.3
7.83
29.40
iu/ml
—
6
74
100
969
1.18
0.23
4.8
4.2
1.43
1.28
mmol/l
0.88
89
890
38
346
1.14
0.23
4.8
5.0
2.43
2.15
ug/l
0.27
32
307
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
4.6
—
136.64
—
0
12
65
684
0.89
0.21
2.8
2.9
63.63
48.35
u/l
0.43
56
642
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
8
69
1.17
0.17
1.6
2.1
—
—
—
0
0
14
159
0.87
0.14
1.1
1.4
—
—
—
0
0
104
1022
1.12
0.11
6.1
5.2
2.78
2.76
mmol/l
0.07
94
943
23
214
1.09
0.09
1.7
1.7
513.72
498.18
pmol/l
0.07
18
180
13
144
0.89
0.09
1.5
1.4
—
—
—
0
0
19
204
0.92
0.07
1.3
1.2
0.46
1.09
u/ml
—
5
54
29
276
1.07
0.06
4.1
4.4
23.64
20.99
%
0.43
20
135
42
406
1.05
0.06
5.0
3.6
77.95
33.54
ng/l
0.52
35
291
101
999
1.06
0.04
5.5
4.7
1.39
1.49
mmol/l
1.74
91
919
13
126
1.04
0.00
4.8
6.4
2.07
1.51
mmol/l
—
8
106
13
129
1.01
0.00
4.2
5.9
104.31
103.89
mmol/l
0.13
13
129
39
395
0.98
0.00
5.1
3.8
—
—
—
0
0
101
1005
1.03
0.00
5.6
4.7
4.66
4.70
mmol/l
0.19
92
933
10
95
1.06
0.00
3.5
2.9
3.63
2.69
mmol/l
—
10
74
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.00
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
-0.00
4.3
7.4
0.43
0.70
%
—
7
75
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
4.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
10.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
-0.00
4.3
7.4
1.00
1.53
%
—
7
76
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: E4_MERETOJA_DISEASE – Meretoja disease
GWS hits: 16
This endpoint is excluded (different definition than used in FinnGen).