amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
667 |
4. Check minimum number of eventsNone |
667 |
5. Include endpointsNone |
667 |
6. Filter based on genotype QC (FinnGen only) |
656 |
Control definitions (FinnGen only)
- Control exclude
- E4_METABOLIA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Amyloidosis, other/unspecified
based on the number of shared cases.
Similar with more cases:
- Amyloidosis
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5263 | 2849 | 2321 |
| Only index persons | 3048 | 1579 | 1469 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.07 | 0.08 | 0.06 |
| Only index persons | 0.06 | 0.06 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 67.37 | 66.72 | 68.27 |
| Only index persons | 68.90 | 67.88 | 69.99 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 656 | 314 | 342 |
| Unadjusted period prevalence (%) | 0.13 | 0.11 | 0.16 |
| Median age at first event (years) | 68.80 | 64.94 | 72.33 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 667
- Matched controls
- 6670
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E85.9
ICD-10 Finland
Amyloidosis, unspecified
+∞
300.5
265
*
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
+∞
143.0
132
*
I43.1*E85.9
ICD-10 Finland
Cardiac amyloidosis
+∞
131.7
122
*
E85.80
ICD-10 Finland
Meretoja sick
+∞
118.3
110
*
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
+∞
117.2
109
*
E85.89
ICD-10 Finland
Other amyloidosis
+∞
116.1
108
*
C90.0
ICD-10 Finland
Multiple myeloma
25.1
102.8
74
33
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
20.1
100.7
80
45
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
19.5
100.5
81
47
XW000
NOMESCO Finland
Bone marrow biopsy
10.6
100.5
120
135
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
9.1
88.2
119
156
C03CA01
ATC
furosemide; systemic
4.6
82.5
390
1576
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
80.9
76
*
E85.4
ICD-10 Finland
Organ-limited amyloidosis
+∞
79.8
75
*
A11CC03
ATC
alfacalcidol; systemic
16.6
75.2
65
43
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
16.9
69.1
59
38
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
+∞
67.9
64
*
153
Kela drug reimbursment
Lenalidomid
29.4
65.2
44
16
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
6.7
62.9
111
194
Z49.1
ICD-10 Finland
Extracorporeal dialysis
19.2
62.6
50
28
A12AA04
ATC
calcium carbonate; oral
19.2
62.6
50
28
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
21.9
62.4
47
23
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
20.6
62.0
48
25
TK800
NOMESCO Finland
Hemodialysis
13.2
58.0
57
47
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
18.2
56.2
46
27
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
23.6
54.8
40
18
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
15.7
53.3
47
32
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
16.2
50.7
44
29
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
18.1
50.1
41
24
N18.0
ICD-10 Finland
End-stage renal disease
17.0
47.3
40
25
L01BA01
ATC
methotrexate; systemic
7.6
44.9
67
97
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
44.9
431
2432
I50.9
ICD-10 Finland
Heart failure, unspecified
3.6
43.4
186
653
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
7.1
42.9
68
105
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.1
41.8
249
1065
V03AE01
ATC
polystyrene sulfonate; oral
16.7
41.2
35
22
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
40.9
187
682
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
16.0
40.2
35
23
L04AA01
ATC
[U] ciclosporin
14.4
40.2
37
27
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.3
39.8
202
783
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
5.0
39.1
91
203
M04AA01
ATC
allopurinol; systemic
3.4
37.0
161
566
I50.0
ICD-10 Finland
Congestive heart failure
4.3
36.9
108
289
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
12.6
36.2
36
30
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.1
36.1
194
773
B03XA01
ATC
erythropoietin; parenteral
14.4
35.9
33
24
N18.8
ICD-10 Finland
Other chronic renal failure
8.4
34.9
47
60
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.5
34.6
144
490
H16.0
ICD-10 Finland
Corneal ulcer
5.6
34.3
69
135
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.8
34.2
83
191
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
14.0
34.2
32
24
N19
ICD-10 Finland
Unspecified kidney failure
6.3
34.1
60
103
C03DA01
ATC
spironolactone; oral
3.4
33.7
142
487
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
67.0
33.4
38
6
B03XA02
ATC
darbepoetin alfa; parenteral
8.0
33.1
46
61
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.5
32.9
131
433
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
6.3
32.8
58
100
N08.4
ICD-10 Finland
Glomerular disorders in other endocrine, nutritional and metabolic diseases
+∞
32.6
31
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
6.7
32.2
53
85
2773B
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS SECUNDARIA]
+∞
31.5
30
*
I68.0
ICD-10 Finland
Cerebral amyloid angiopathy
+∞
31.5
30
*
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
5.5
30.7
63
125
AA1AD
NOMESCO Finland
CT of head and brain
2.7
30.6
250
1230
E85.0
ICD-10 Finland
Non-neuropathic heredofamilial amyloidosis
+∞
30.4
29
*
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.6
29.8
76
182
E85.8
ICD-10 Finland
Other amyloidosis
+∞
29.4
28
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
6.1
28.9
52
91
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.5
28.5
111
360
H02AB02
ATC
dexamethasone; systemic
3.2
28.0
130
469
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
10.4
27.6
31
31
L04AX01
ATC
azathioprine; systemic
5.7
27.3
53
100
L04AX04
ATC
lenalidomide; oral
26.0
26.9
37
15
L04AA06
ATC
mycophenolic acid; systemic
9.8
26.4
31
33
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.2
25.9
117
415
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.1
25.4
75
200
R4120
NOMESCO Finland
Occupational therapy
4.3
25.3
70
178
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.1
24.6
119
438
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
58.3
24.2
28
5
KA1AE
NOMESCO Finland
Kidney ultrasound examination
6.2
24.1
42
71
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
3.3
23.7
98
328
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
25.8
23.3
32
13
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
6.8
23.2
37
57
L99.0*E85.9
ICD-10 Finland
Amyloidosis of skin
+∞
23.0
22
*
329
Kela drug reimbursment
Lenalidomide
31.3
23.0
30
10
A04AA01
ATC
ondansetron; systemic, rectal
3.4
22.5
88
284
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.1
22.4
105
379
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.8
22.4
128
516
137
Kela drug reimbursment
Uraemia requiring dialysis
24.9
22.3
31
13
XF404
NOMESCO Finland
Ambulatory ECG
3.3
22.3
94
318
WW200
NOMESCO Finland
Immunization
7.6
22.2
32
44
L01AA03
ATC
melphalan; systemic
32.4
21.6
28
9
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
21.5
282
1657
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.4
21.3
195
984
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.8
21.1
68
193
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
7.9
21.0
29
38
H19.8
ICD-10 Finland
Other disorders of sclera and cornea in diseases classified elsewhere
+∞
20.9
20
*
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.6
20.9
74
224
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
4.9
20.9
47
101
ZX120
NOMESCO Finland
Intravenous
3.1
20.7
94
332
J05AB01
ATC
aciclovir; systemic
2.4
20.6
184
918
C07AB07
ATC
bisoprolol; oral
2.1
20.0
389
2638
WX892
NOMESCO Finland
Monitored bed care
3.4
20.0
78
251
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
6.5
19.9
33
53
I43.1
ICD-10 Finland
Cardiomyopathy in metabolic diseases
+∞
19.9
19
*
Z3231
NOMESCO Finland
Registered nurse
2.3
19.8
214
1154
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
5.4
19.8
40
78
ZX112
NOMESCO Finland
Subcutaneous
5.9
19.6
36
64
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
5.0
19.4
43
91
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
8.6
19.4
25
30
Z31.5
ICD-10 Finland
Genetic counselling
4.6
19.3
47
108
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
27.0
19.2
26
10
Z49.0
ICD-10 Finland
Preparatory care for dialysis
18.9
19.2
29
16
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
19.1
234
1325
WW300
NOMESCO Finland
Transfer of autologic stem cells
35.5
19.0
24
7
L04AA13
ATC
[U] leflunomide
6.1
18.9
33
56
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
7.9
18.8
26
34
ACC51
NOMESCO Finland
Release of median nerve
3.3
18.8
78
261
Z3226
NOMESCO Finland
Physiotherapist
2.4
18.7
151
716
ZXA05
NOMESCO Finland
Left side
2.2
18.5
212
1166
WX002
NOMESCO Finland
Sedation and analgesia
2.3
18.4
171
862
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
18.4
80
275
QAJ10
NOMESCO Finland
Browlift
45.4
18.3
22
5
Z2446
NOMESCO Finland
Social worker
3.6
18.1
64
193
Z94.0
ICD-10 Finland
Kidney transplant status
17.1
18.0
28
17
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.7
17.8
109
452
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.6
17.7
123
543
J01MA12
ATC
levofloxacin; systemic
2.3
17.5
163
821
L04AD01
ATC
ciclosporin; systemic
7.3
17.5
26
37
R80
ICD-10 Finland
Isolated proteinuria
19.3
17.4
26
14
ZXD05
NOMESCO Finland
Urgent procedure
2.1
17.1
219
1251
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
6.1
17.1
30
51
R4110
NOMESCO Finland
Physiotherapy
2.1
16.9
206
1155
E85
ICD-10 Finland
Amyloidosis
+∞
16.7
16
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
16.8
16.7
26
16
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
28.4
16.6
22
8
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
16.6
174
919
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.9
16.5
37
79
127
Kela drug reimbursment
Transplant complication
12.6
16.5
29
24
C09AA05
ATC
ramipril; oral
2.1
16.4
214
1228
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
6.7
16.3
26
40
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.3
16.1
33
65
N08.4*E85.80
ICD-10 Finland
Glomerular disease in Meretoja's patients
+∞
15.7
15
*
N07XX08
ATC
tafamidis; oral
+∞
15.7
15
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
19.8
15.6
23
12
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
22.7
15.6
22
10
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.0
15.6
34
71
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.0
15.6
75
273
R06.0
ICD-10 Finland
Dyspnoea
2.1
15.5
210
1218
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.3
15.5
61
197
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
12.7
15.5
27
22
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
15.5
100
425
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.4
15.4
126
597
A28
ICPC
Limited function/disability NOS
2.2
15.4
148
752
C10AA05
ATC
atorvastatin; oral
1.9
15.4
305
2020
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
15.5
15.0
24
16
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.9
15.0
322
2185
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
58.0
14.8
17
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.9
14.8
74
275
B05DA
ATC
Isotonic solutions
21.6
14.7
21
10
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.3
14.6
39
96
3011
Kela drug reimbursment
Tafamidis
+∞
14.6
14
*
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
36.9
14.5
18
5
R60.0
ICD-10 Finland
Localized oedema
2.5
14.5
106
477
CG2T4
NOMESCO Finland
Topography assessment of cornea
12.9
14.5
25
20
XF402
NOMESCO Finland
ECG with work load test
2.6
14.5
91
381
B01AB05
ATC
enoxaparin; parenteral
1.9
14.5
245
1531
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.6
14.2
34
77
201
Kela drug reimbursment
Chronic cardiac insufficiency
3.2
14.1
59
198
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.9
14.1
72
271
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
30.8
13.9
18
6
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
30.8
13.9
18
6
H02.2
ICD-10 Finland
Lagophthalmos
18.0
13.9
21
12
B01AC04
ATC
clopidogrel; oral
2.2
13.9
131
658
N02AX02
ATC
tramadol; systemic, rectal
1.9
13.8
313
2142
ZX108
NOMESCO Finland
Inhalation
14.0
13.8
23
17
L28
ICPC
Limited function/disability (L)
2.1
13.7
149
791
Z2221
NOMESCO Finland
Medical doctor
2.0
13.6
188
1091
9256
FHL
Synovectomy (knee 9311)
142.8
13.5
14
*
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
11.8
13.4
24
21
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
13.4
74
290
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.1
13.3
59
205
H02.3
ICD-10 Finland
Blepharochalasis
2.9
13.2
66
245
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.6
13.1
44
128
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.8
13.0
71
276
H02AB06
ATC
prednisolone; systemic
1.8
13.0
331
2334
A46
ICD-10 Finland
Erysipelas
2.2
13.0
120
597
TFJ02
NOMESCO Finland
Muscle biopsy of heart
23.1
12.9
18
8
WX872
NOMESCO Finland
Intensive care
3.3
12.9
50
160
1XX32, ,
NOMESCO Finland
51.0
12.9
15
*
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
51.0
12.9
15
*
AA1AA
NOMESCO Finland
Head X-ray examination
10.8
12.8
24
23
H02AB09
ATC
hydrocortisone; systemic
5.6
12.7
24
44
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
12.7
126
645
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
12.7
92
412
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.6
12.6
76
311
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
32.7
12.6
16
5
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
12.5
12
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
20.5
12.5
18
9
Z49.2
ICD-10 Finland
Other dialysis
20.5
12.5
18
9
H02.4
ICD-10 Finland
Ptosis of eyelid
4.0
12.5
36
94
B01AF02
ATC
apixaban; oral
2.2
12.4
111
544
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
6.0
12.3
22
38
A07AA09
ATC
vancomycin; oral
9.9
12.3
24
25
V03AE02
ATC
sevelamer; oral
27.3
12.1
16
6
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.9
11.9
195
1192
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
11.9
200
1233
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
11.8
122
633
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
30.6
11.7
15
5
E87.5
ICD-10 Finland
Hyperkalaemia
23.4
11.6
16
7
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.6
11.5
27
60
ZXE00
NOMESCO Finland
One hour or less
1.8
11.5
264
1787
2773A
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS PRIMARIA]
+∞
11.5
11
*
CBH25
NOMESCO Finland
Tarsorrhaphy
122.0
11.5
12
*
NCB20
NOMESCO Finland
Primary total prosthetic replacement of elbow joint
122.0
11.5
12
*
ZXA00
NOMESCO Finland
Right side
1.9
11.4
205
1288
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
12.1
11.4
20
17
9283
FHL
Subtalar joint ossification surgery (or triple)
35.7
11.3
14
*
R55
ICD-10 Finland
Syncope and collapse
2.3
11.3
92
433
R50.9
ICD-10 Finland
Fever, unspecified
2.2
11.2
112
572
A07EC01
ATC
sulfasalazine; oral, rectal
2.6
11.2
67
273
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
11.2
78
342
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.6
11.2
66
267
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.2
11.2
44
142
B05DB
ATC
Hypertonic solutions
25.5
11.2
15
6
H02.1
ICD-10 Finland
Ectropion of eyelid
8.8
11.1
23
27
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
11.1
126
677
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
5.9
11.1
20
35
ZXA10
NOMESCO Finland
Bilateral
2.0
11.0
151
868
ZXE20
NOMESCO Finland
More than three and less than five hours
2.1
10.9
110
564
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.8
10.9
277
1925
CG2S4
NOMESCO Finland
Photography of cornea
18.2
10.8
16
9
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.4
10.7
82
375
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.0
10.7
49
173
S01XA18
ATC
ciclosporin; ophthalmic
13.2
10.7
18
14
XCK10
NOMESCO Finland
Photography of fundus of eye
2.4
10.7
81
369
L04AX03
ATC
methotrexate; systemic
2.4
10.6
76
337
B01AB04
ATC
dalteparin; parenteral
3.0
10.6
49
174
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
11.5
10.6
19
17
C08CA01
ATC
amlodipine; oral
1.7
10.6
282
1980
G51.0
ICD-10 Finland
Bell palsy
4.1
10.6
29
73
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
3.1
10.6
46
158
E85.2
ICD-10 Finland
Heredofamilial amyloidosis, unspecified
+∞
10.4
10
*
L88
ICPC
Rheumatoid/seropositive arthritis
3.3
10.4
39
122
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
12.3
10.4
18
15
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.9
10.3
30
79
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.7
10.3
24
53
E83.50
ICD-10 Finland
Hypercalcemia
23.8
10.3
14
6
E86
ICD-10 Finland
Volume depletion
23.8
10.3
14
6
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
10.1
91
445
H02AB07
ATC
prednisone; oral
2.1
10.1
106
551
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
3.8
10.1
31
85
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
10.0
226
1509
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.3
10.0
38
120
CBF99
NOMESCO Finland
Other operation for ectropion
40.7
10.0
12
*
L04AC07
ATC
tocilizumab; parenteral
40.7
10.0
12
*
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
9.9
427
3392
S18
ICPC
Laceration/cut
1.7
9.8
329
2444
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
9.7
129
730
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
13.6
9.7
16
12
B01AA03
ATC
warfarin; systemic
1.8
9.7
161
980
J05AB11
ATC
valaciclovir; oral
2.0
9.7
109
582
ZZC00
NOMESCO Finland
Graft of fascia
55.8
9.7
11
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
55.8
9.7
11
*
XX9XE
NOMESCO Finland
Other ultrasound examination
10.2
9.6
18
18
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
9.5
81
388
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.4
9.5
68
302
9272
FHL
Metatarsophalangeal joint resection
17.8
9.4
14
8
A12AA12
ATC
[U] calcium acetate
30.5
9.4
12
*
QAJ30
NOMESCO Finland
Other facelift
30.5
9.4
12
*
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
3.0
9.4
41
141
27699
ICD-8 Finland
Amyloidosis
+∞
9.4
9
*
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
7.1
9.4
22
32
L01AA02
ATC
chlorambucil; oral
22.1
9.4
13
6
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
9.3
59
247
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
9.3
129
740
RS221, ,
NOMESCO Finland
7.4
9.3
21
29
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
9.2
101
533
L03AA02
ATC
filgrastim; parenteral
3.5
9.1
32
96
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
9.1
77
367
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.1
9.1
99
521
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
9.1
161
997
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
9.1
123
699
H16.9
ICD-10 Finland
Keratitis, unspecified
7.2
9.1
21
30
205
Kela drug reimbursment
Chronic hypertension
1.7
9.1
204
1355
TK810
NOMESCO Finland
Hemofiltration
15.8
9.1
14
9
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
2.3
9.0
71
329
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
24.4
8.9
12
5
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.0
8.9
40
140
TQW99
NOMESCO Finland
Other minor procedure on skin
2.6
8.9
50
198
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.6
8.9
50
198
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
8.9
135
798
S97
ICPC
Chronic ulcer skin
2.5
8.8
56
235
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.0
8.8
38
130
212
Kela drug reimbursment
Gout
4.2
8.8
23
56
K90
ICPC
Stroke/cerebrovascular accident
4.0
8.8
25
65
E0000UV, ,
ATC
1.7
8.6
258
1843
207
Kela drug reimbursment
Chronic arrhythmias
1.9
8.6
132
781
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
8.6
138
829
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
8.5
109
607
C10AA01
ATC
simvastatin; oral
1.6
8.5
292
2157
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
20.3
8.5
12
6
C02AC05
ATC
moxonidine; oral
2.9
8.5
40
144
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.1
8.5
36
122
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.7
8.4
46
179
I42.5
ICD-10 Finland
Other restrictive cardiomyopathy
91.2
8.4
9
*
L04AB04
ATC
adalimumab; parenteral
5.0
8.4
18
37
FFM32
NOMESCO Finland
Occlusion or excision of atrial appendage transvenously with a closing device
+∞
8.3
8
*
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
8.3
430
3503
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
8.3
148
916
P01BA02
ATC
hydroxychloroquine; oral
2.3
8.3
65
300
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.5
8.3
51
211
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
8.3
77
382
D06BB04
ATC
podophyllotoxin; topical
3.7
8.2
26
73
R60.9
ICD-10 Finland
Oedema, unspecified
2.7
8.2
44
170
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
4.8
8.2
18
38
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.4
8.1
58
257
L04AB01
ATC
etanercept; parenteral
8.3
8.1
17
21
TK820
NOMESCO Finland
Peritoneal dialysis
17.4
8.1
12
7
L01CB
ATC
Podophyllotoxin derivatives
33.8
8.1
10
*
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
33.8
8.1
10
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
3.1
8.0
34
115
9314
FHL
Total knee endoprosthesis (also includes patellar part)
22.3
8.0
11
5
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
22.3
8.0
11
5
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.7
8.0
43
166
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
8.0
242
1727
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
7.9
105
592
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.3
7.9
63
293
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
13.2
7.9
13
10
JN4AD
NOMESCO Finland
Body CT examination
2.1
7.9
82
424
M01CB01
ATC
sodium aurothiomalate; parenteral
6.2
7.9
20
33
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
7.9
282
2094
H25.1
ICD-10 Finland
Senile nuclear cataract
1.6
7.8
228
1610
3AC01, ,
NOMESCO Finland
9.6
7.8
15
16
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
6.5
7.8
19
30
9289
FHL
Other measure in this category
45.5
7.7
9
*
B74
ICPC
Malignant neoplasm blood other
45.5
7.7
9
*
N05CF01
ATC
zopiclone; oral
1.6
7.7
220
1544
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.6
7.7
18
40
J01MA02
ATC
ciprofloxacin; systemic
1.6
7.6
258
1886
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
18.6
7.6
11
6
WW409
NOMESCO Finland
Other aferesis
25.3
7.6
10
*
N30.0
ICD-10 Finland
Acute cystitis
1.9
7.6
94
518
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
10.2
7.6
14
14
S01AD03
ATC
aciclovir; ophthalmic
3.0
7.5
32
109
M80.0
ICD-10 Finland
Postmenopausal osteoporosis with pathological fracture
4.0
7.5
21
54
A02BC02
ATC
pantoprazole; systemic
1.6
7.5
442
3673
7143C
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SERONEGATIVA]
81.0
7.4
8
*
N17.8
ICD-10 Finland
Other acute renal failure
7.8
7.4
16
21
WZC00
NOMESCO Finland
Treatment plan or consultation
1.6
7.4
222
1574
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
7.4
58
268
J01DB01
ATC
cefalexin; oral
1.7
7.4
514
4440
E000001, ,
ATC
1.8
7.3
122
738
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
3.6
7.3
24
69
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
11.0
7.3
13
12
CBB10
NOMESCO Finland
Excision of redundant skin of eyelid
3.4
7.3
26
79
L99.0
ICD-10 Finland
Amyloidosis of skin
+∞
7.3
7
*
QAJ15
NOMESCO Finland
Browlift using video-endoscope
+∞
7.3
7
*
I95.9
ICD-10 Finland
Hypotension, unspecified
4.4
7.3
18
42
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.6
7.2
17
38
J94.8
ICD-10 Finland
Other specified pleural conditions
4.0
7.2
20
51
I95.1
ICD-10 Finland
Orthostatic hypotension
2.9
7.2
34
123
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
7.2
74
382
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
20.3
7.1
10
5
C09AA02
ATC
enalapril; systemic
1.7
7.1
145
929
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
3.8
7.1
21
56
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
7.0
167
1115
H02AB04
ATC
methylprednisolone; systemic
1.9
7.0
98
561
ZZH31
NOMESCO Finland
Bone allograft, small pieces
7.1
7.0
16
23
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
7.0
59
281
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
6.9
246
1810
I50.1
ICD-10 Finland
Left ventricular failure
2.5
6.9
44
185
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.0
6.9
76
401
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
14.0
6.9
11
8
RD210, ,
NOMESCO Finland
6.8
6.8
16
24
TQW40
NOMESCO Finland
Remowal of suture of skin
2.3
6.8
53
244
NDG30
NOMESCO Finland
Fusion of wrist, total
11.1
6.8
12
11
WX730
NOMESCO Finland
Conventional respirator
6.2
6.8
17
28
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
40.5
6.8
8
*
D02AX
ATC
Other emollients and protectives
3.6
6.8
22
63
L04AA11
ATC
[U] etanercept
16.9
6.8
10
6
9284
FHL
Wrist ossification surgery
22.8
6.7
9
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
22.8
6.7
9
*
J01DA01
ATC
[U] cefalexin
1.5
6.7
385
3142
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.2
6.6
57
274
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
3.5
6.6
22
64
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
8.8
6.6
13
15
L01AA01
ATC
cyclophosphamide; systemic
8.8
6.6
13
15
C08CA02
ATC
felodipine; oral
2.0
6.6
74
394
J01FF01
ATC
clindamycin; systemic
1.6
6.5
174
1193
A41.9
ICD-10 Finland
Sepsis, unspecified
2.8
6.5
32
118
SPAT1211
SPAT
Application of soft bandage
2.1
6.5
65
331
J01CF02
ATC
cloxacillin; systemic
3.7
6.5
20
55
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
6.3
6.5
16
26
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.6
6.5
21
60
N03AX14
ATC
levetiracetam; systemic
3.5
6.5
22
65
CBB11
NOMESCO Finland
Resection of lax skin in upper eyelid
3.4
6.5
23
70
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
6.5
43
185
A08
ICPC
Swelling
2.4
6.5
43
185
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.7
6.4
119
742
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
14.5
6.4
10
7
V03AE03
ATC
lanthanum carbonate; oral
14.5
6.4
10
7
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
2.7
6.4
34
131
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.6
6.4
35
137
M05BA04
ATC
alendronic acid; oral
2.0
6.4
73
391
SPAT1229
SPAT
Assessment of need for aid
2.1
6.4
61
306
NHG20
NOMESCO Finland
Fusion of talocrural joint
8.3
6.4
13
16
CBN30
NOMESCO Finland
Shortening of canthal ligament
8.3
6.4
13
16
E87.6
ICD-10 Finland
Hypokalaemia
5.6
6.3
17
31
B01AB10
ATC
tinzaparin; parenteral
2.0
6.3
73
392
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.3
6.3
46
206
K07
ICPC
Swollen ankles/oedema
2.5
6.3
39
162
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
11.2
6.3
11
10
H18.4
ICD-10 Finland
Corneal degeneration
9.4
6.3
12
13
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.9
6.3
79
437
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.8
6.3
31
115
2773C
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS CUTIS]
+∞
6.3
6
*
QAJ35
NOMESCO Finland
Other correction of loose or redundant skin of head or neck
+∞
6.3
6
*
H198, E858,
ICD-10 Finland
+∞
6.3
6
*
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
26.9
6.2
8
*
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.7
6.2
33
127
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.2
124
789
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
4.0
6.2
17
43
C08CA13
ATC
lercanidipine; oral
1.8
6.1
101
608
WX202
NOMESCO Finland
Supraclavicular plexus blockade
4.2
6.1
16
39
250, ,
Kela drug reimbursment
4.2
6.1
16
39
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
12.7
6.1
10
8
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.4
6.1
39
165
R13
ICD-10 Finland
Dysphagia
2.2
6.1
51
243
R4130
NOMESCO Finland
Speech therapy
3.5
6.0
20
58
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.3
6.0
22
68
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
5.3
6.0
17
33
R42
ICD-10 Finland
Dizziness and giddiness
1.6
6.0
153
1035
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
226
189
17.57
238.23
11.8
3.8
65.65
84.94
mg/l
0.21
196
153
226
189
17.57
238.23
11.9
3.8
67.75
48.42
mg/l
0.52
195
156
221
185
17.37
232.52
11.8
3.7
2.49
2.24
ratio
0.06
17
16
280
483
9.27
171.25
7.8
2.7
62.86
66.16
g/l
6.46
270
438
94
51
21.29
120.72
5.2
2.3
1.90
1.38
g/24h
0.32
53
21
90
46
22.46
118.59
3.8
2.0
—
—
—
0
0
263
622
6.33
113.34
11.3
4.9
1.14
1.02
mmol/l
8.31
254
570
158
226
8.85
109.96
8.0
2.4
7.36
7.30
g/l
0.14
152
204
157
226
8.78
108.62
8.0
2.4
3.23
3.52
g/l
0.91
151
204
157
226
8.78
108.62
8.0
2.4
—
—
—
0
0
152
213
8.95
107.49
8.2
2.4
2.69
3.02
g/l
2.99
146
192
143
196
9.01
102.79
8.0
2.6
2.42
1.92
g/l
0.27
128
171
147
215
8.49
99.94
8.0
2.4
8.51
10.67
g/l
4.23
140
193
203
419
6.53
99.75
12.2
6.2
12.83
10.61
mmol/l
3.09
194
394
179
376
6.14
85.37
4.6
2.9
9.18
10.99
g/l
3.63
171
346
234
626
5.22
84.88
6.0
4.5
245.66
241.05
u/l
0.30
229
593
156
297
6.55
82.17
4.0
1.8
1.29
1.68
g/l
0.57
146
270
118
170
8.22
80.57
8.0
2.5
0.04
0.00
g/l
0.76
113
157
118
181
7.71
76.10
7.8
2.4
35.86
37.31
g/l
1.23
111
160
110
160
8.04
74.28
8.2
2.5
0.00
0.00
g/l
-0.00
105
148
110
162
7.93
73.45
8.2
2.5
0.01
0.00
g/l
0.50
105
149
191
484
5.13
72.85
2.6
2.8
65.99
69.05
e9/l
0.59
156
383
218
639
4.58
68.99
2.9
2.6
1.72
1.77
%
0.26
204
573
162
405
4.96
62.04
5.5
2.9
121.20
85.94
ng/l
0.94
143
346
233
780
4.05
60.64
3.1
1.9
29.76
29.76
s
0.00
226
751
219
715
4.07
58.84
4.6
2.3
20.99
22.34
%
0.78
196
610
369
1749
3.48
55.29
7.8
2.9
3578.32
1397.01
ng/l
7.90
348
1493
232
822
3.79
54.89
4.5
2.3
10.95
12.70
umol/l
3.60
226
760
223
778
3.80
53.85
5.3
3.3
0.82
0.83
mmol/l
0.57
214
730
432
2369
3.34
48.73
10.7
4.3
32.41
35.20
g/l
14.64
413
2180
442
2510
3.26
45.90
14.1
5.2
1.21
1.21
mmol/l
0.58
416
2254
430
2407
3.21
45.72
10.9
5.6
2.60
2.89
%
2.31
413
2236
467
2747
3.33
45.46
18.1
5.9
1.21
1.22
mmol/l
0.57
402
2326
434
2454
3.20
45.10
11.1
5.8
24.45
26.99
%
4.74
418
2285
428
2421
3.14
44.05
10.6
5.5
60.80
57.70
%
5.64
410
2259
293
1343
3.11
43.97
5.7
2.7
1335.36
7353.63
umol/l
3.03
271
1147
317
1583
2.91
39.80
3.1
2.0
174.75
245.55
u/l
0.73
299
1491
216
893
3.10
37.92
2.4
1.8
—
—
—
0
0
102
257
4.50
37.71
1.9
2.1
1.53
1.57
g/l
0.13
92
221
212
888
3.03
36.14
3.4
1.4
2.17
2.59
g/l
1.49
166
517
470
2984
2.95
35.96
17.3
8.8
4.41
4.05
e9/l
3.06
430
2626
39
7
59.02
33.60
1.3
1.3
—
—
—
0
0
346
1992
2.53
30.32
5.0
3.0
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
72
165
4.77
29.75
3.6
2.6
0.33
0.32
u/ml
0.04
45
86
134
481
3.23
29.23
5.3
2.9
443.05
221.71
ng/l
3.20
127
445
358
2123
2.48
29.02
7.5
3.4
63.73
54.77
ng/l
0.22
311
1586
214
1002
2.67
28.61
8.9
3.5
219.86
372.81
ng/l
0.76
203
811
56
107
5.62
28.44
1.3
1.4
—
—
—
0
0
349
2067
2.44
28.07
4.3
2.6
187.73
149.88
ug/l
2.27
325
1865
416
2680
2.47
27.52
18.0
16.2
1.32
1.32
inr
0.04
111
775
466
3171
2.56
27.20
8.5
4.4
6.63
6.68
mmol/l
0.20
452
2959
151
604
2.94
27.14
2.2
1.7
—
—
—
0
0
37
15
26.01
26.85
1.1
1.5
—
—
—
0
0
52
98
5.67
26.77
4.4
5.5
1200.00
208.79
iu/ml
0.53
12
14
150
604
2.91
26.59
2.3
1.7
—
—
—
0
0
107
356
3.39
26.26
2.2
1.6
—
—
—
0
0
288
1624
2.36
25.14
5.7
3.0
2612.49
351.23
mg/l
3.65
223
1010
257
1383
2.40
24.93
2.5
2.1
3.01
3.27
mg/l
0.98
228
1170
421
2802
2.36
24.76
9.2
6.2
11.08
11.69
umol/l
0.72
410
2653
288
1643
2.33
24.26
4.8
3.1
32.69
120.31
e6/l
1.34
250
1294
315
1892
2.26
23.18
5.7
3.5
71.64
132.00
e6/l
0.80
256
1388
287
1660
2.28
23.13
4.5
2.9
5.81
7.49
mmol/l
11.05
257
1369
96
325
3.28
22.79
5.7
3.4
1.18
2.05
mmol/l
1.57
74
256
269
1522
2.29
22.78
4.8
3.0
0.44
0.50
e6/l
0.16
234
1183
47
94
5.30
22.66
1.7
1.4
24.16
31.40
g/l
3.11
38
85
291
1721
2.23
21.92
5.4
3.5
79.23
6.48
mg/mmol
9.08
222
1047
73
212
3.74
21.91
7.4
3.6
24.01
24.25
mmol/l
0.29
73
206
98
348
3.13
21.44
5.8
3.4
4.93
5.18
kpa
2.69
93
336
204
1054
2.35
21.11
2.1
1.6
1.77
1.37
mg/l
0.36
159
801
330
2076
2.17
21.02
3.0
2.1
75.97
79.51
nmol/l
1.53
309
1791
60
156
4.13
21.00
1.3
1.4
0.24
0.22
g/l
0.44
55
149
116
460
2.84
20.81
7.1
3.1
5.99
5.84
kpa
1.00
116
442
115
459
2.82
20.36
7.2
3.1
2.00
2.22
mmol/l
0.27
100
379
60
162
3.97
19.94
1.3
1.4
1.15
1.12
g/l
0.30
55
156
303
1889
2.11
19.28
4.6
3.4
2.33
2.35
mmol/l
2.80
269
1618
92
337
3.01
18.99
2.0
1.5
—
—
—
0
0
129
566
2.59
18.88
3.3
2.6
7.14
8.85
umol/l
0.68
118
490
42
91
4.86
18.46
1.6
1.4
—
—
—
0
0
54
144
3.99
18.24
2.0
1.6
—
—
—
0
0
531
4160
2.36
17.86
15.8
7.3
84.83
78.27
u/l
2.05
512
3862
52
137
4.03
17.85
1.4
1.2
—
—
—
0
0
513
3964
2.27
17.80
7.2
4.1
19.88
13.20
mm/h
9.77
486
3613
212
1182
2.16
17.77
3.7
2.4
3.61
4.89
e6/l
1.86
197
1061
44
103
4.50
17.61
1.5
2.5
34.58
32.51
umol/l
0.13
38
90
39
83
4.93
17.50
1.5
1.3
655.54
1322.26
e6/l
1.50
28
61
22
7
32.43
17.12
6.8
2.7
—
—
—
0
0
51
139
3.89
16.71
1.9
1.7
—
—
—
0
0
36
75
5.02
16.55
1.5
1.3
47375.13
136428.13
e6/l
0.49
16
45
162
846
2.21
15.77
4.1
2.8
3.54
2.06
e6/l
0.92
105
477
28
49
5.92
15.51
3.3
2.4
—
—
—
0
0
41
101
4.26
15.38
2.0
1.6
—
—
—
0
0
41
101
4.26
15.38
2.0
1.6
—
—
—
0
0
63
210
3.21
15.21
1.3
1.9
38.60
38.35
u/l
0.03
51
187
229
1399
1.97
14.44
1.9
1.5
20.80
21.08
nmol/l
0.09
200
1153
24
39
6.35
14.29
1.1
1.0
—
—
—
0
0
94
404
2.54
14.16
2.4
2.0
383.60
364.04
nmol/l
0.34
89
368
34
78
4.54
13.95
1.6
1.4
117.00
107.00
u/ml
—
5
12
123
619
2.21
12.91
7.7
7.2
4.75
5.15
kpa
4.22
114
584
123
619
2.21
12.91
7.7
7.1
0.81
1.38
mmol/l
0.72
95
464
191
1140
1.95
12.62
2.0
1.7
1064.56
1176.84
nmol/l
0.86
154
852
49
158
3.27
12.48
1.8
1.5
—
—
—
0
0
122
620
2.18
12.47
7.8
7.1
12.01
12.06
kpa
0.03
112
585
163
926
2.01
12.39
3.9
2.7
1.15
1.17
e6/l
0.02
105
554
326
2317
1.80
12.25
2.6
2.0
92.83
95.16
pmol/l
0.37
188
1186
47
151
3.27
12.04
1.3
1.6
—
—
—
0
0
31
77
4.17
11.51
7.1
6.3
13.09
11.33
mg/l
1.39
31
72
235
1537
1.82
11.48
4.4
3.1
32.49
32.21
u/l
0.05
224
1445
340
2498
1.74
10.97
3.8
2.6
—
—
—
0
0
113
586
2.12
10.89
5.2
3.2
—
—
—
0
0
101
504
2.18
10.73
2.2
2.2
0.19
0.20
g/l
0.93
96
471
203
1293
1.82
10.69
3.7
2.4
—
—
—
0
0
38
116
3.41
10.55
5.0
2.4
15.35
15.84
%
0.26
22
52
30
78
3.98
10.49
1.3
1.3
—
—
—
0
0
35
103
3.53
10.28
2.0
1.7
—
—
—
0
0
27
66
4.22
10.24
2.0
1.9
—
—
—
0
0
20
38
5.39
10.17
1.0
1.3
—
—
—
0
0
21
42
5.13
10.10
1.2
1.3
—
—
—
0
0
32
90
3.68
10.04
4.7
3.2
58.09
58.46
%
0.05
32
90
26
63
4.25
9.98
2.0
2.0
—
—
—
0
0
343
2574
1.68
9.85
5.0
3.8
0.00
0.00
estimate
-0.00
84
535
96
488
2.13
9.70
2.6
2.3
5.58
7.27
ug/l
0.87
81
433
239
1645
1.71
9.39
3.2
2.3
62.09
62.48
u/l
0.03
222
1498
35
110
3.30
9.30
4.5
2.2
121.45
127.25
g/l
0.70
29
83
339
2562
1.66
9.28
6.9
5.0
0.00
0.00
estimate
-0.00
82
500
343
2600
1.66
9.28
5.1
3.8
0.00
0.01
estimate
0.80
73
490
30
86
3.61
9.17
4.7
2.8
4.31
4.47
e9/l
0.14
30
86
57
240
2.50
8.92
2.5
1.9
1.14
3.28
ug/l
0.98
51
212
30
89
3.48
8.72
1.5
1.4
—
—
—
0
0
52
212
2.58
8.69
1.9
3.2
—
—
—
0
0
33
109
3.13
8.11
1.6
1.4
—
—
—
0
0
30
96
3.23
7.77
1.5
1.1
—
—
—
0
0
21
53
4.06
7.66
1.3
1.2
5.44
11.30
u/l
4.24
16
47
389
3131
1.58
7.59
3.9
3.0
66.96
50.22
u/l
1.90
367
2868
30
98
3.16
7.52
1.7
1.4
—
—
—
0
0
461
3873
1.62
7.40
4.2
3.7
15.15
15.00
pmol/l
0.52
420
3448
26
79
3.38
7.31
2.5
1.6
89.84
89.63
%
0.05
26
79
32
111
2.98
7.26
1.3
1.3
—
—
—
0
0
32
111
2.98
7.26
1.3
1.3
—
—
—
0
0
583
5232
1.91
7.16
36.4
14.1
23.61
26.15
mg/l
1.23
522
4120
53
239
2.32
7.16
2.6
1.9
—
—
—
0
0
24
71
3.47
7.03
1.6
1.5
—
—
—
0
0
24
71
3.47
7.03
1.6
1.5
—
—
—
0
0
37
143
2.68
6.90
1.5
1.4
—
—
—
0
0
81
440
1.96
6.79
3.2
2.8
40.46
63.05
ml/min/173m2
6.74
46
158
64
320
2.11
6.73
1.4
1.4
—
—
—
0
0
17
29
5.99
6.64
1.5
1.4
—
—
—
0
0
17
29
5.99
6.64
1.5
1.4
—
—
—
0
0
11
9
12.40
6.60
11.5
14.0
4.49
6.29
mmol/l
—
11
9
111
674
1.78
6.57
9.3
6.2
103.89
104.48
mmol/l
0.58
111
674
20
55
3.72
6.52
2.3
1.7
—
—
—
0
0
20
55
3.72
6.52
2.4
1.7
—
—
—
0
0
20
55
3.72
6.52
2.4
1.7
—
—
—
0
0
17
30
5.79
6.49
2.4
2.1
—
—
—
0
0
17
30
5.79
6.49
2.4
2.1
—
—
—
0
0
538
4763
1.67
6.34
5.2
4.5
2.06
2.00
mu/l
0.62
492
4250
36
144
2.59
6.29
2.0
1.6
18570.58
10933.78
e6/l
0.59
26
105
163
1113
1.61
6.20
2.9
3.1
2.49
2.46
mmol/l
2.86
145
972
33
129
2.64
6.04
1.3
1.2
733.45
490.02
mg/l
1.59
33
118
21
63
3.41
6.04
1.1
1.2
1.80
4.31
u/ml
—
5
36
79
444
1.88
5.99
2.6
2.5
45.97
32.14
u/l
1.13
66
381
47
218
2.24
5.97
2.1
1.8
—
—
—
0
0
9
6
15.17
5.91
5.2
4.3
—
—
—
0
0
17
45
3.85
5.84
1.1
1.1
—
—
—
0
0
14
23
6.19
5.71
2.5
2.3
—
—
—
0
0
14
23
6.19
5.71
2.5
2.3
—
—
—
0
0
14
24
5.93
5.55
2.5
2.3
—
—
—
0
0
17
47
3.69
5.51
1.3
1.3
14.06
13.64
u/l
0.06
17
42
12
17
7.17
5.45
1.2
2.4
129.75
93.06
%
2.90
12
17
20
63
3.24
5.35
1.6
1.5
—
—
—
0
0
51
256
2.07
5.34
5.8
2.7
24.62
25.45
mmol/l
0.73
51
246
316
2572
1.43
4.97
2.9
2.4
—
—
—
0
0
16
37
4.40
4.96
1.0
1.1
—
87.50
—
0
8
24
89
2.76
4.89
1.4
1.1
216.22
309.83
u/ml
0.79
18
53
14
29
4.91
4.83
1.1
1.0
—
—
—
0
0
37
171
2.23
4.78
1.7
1.3
—
—
—
0
0
16
47
3.46
4.77
1.1
1.1
—
—
—
0
0
12
21
5.80
4.77
1.2
1.1
—
—
—
0
0
27
109
2.54
4.68
1.2
1.2
4.00
35.65
e6/l
0.56
21
84
27
109
2.54
4.68
1.3
1.3
609.90
1141.09
e6/l
0.20
21
87
13
26
5.08
4.65
1.6
1.3
—
—
—
0
0
13
26
5.08
4.65
1.6
1.3
—
—
—
0
0
27
110
2.52
4.60
2.7
1.6
—
—
—
0
0
7
5
14.13
4.58
1.0
1.2
—
—
—
0
0
16
49
3.32
4.49
1.1
1.1
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
9
12
7.58
4.36
1.4
3.6
218.11
172.11
%
—
9
12
15
38
4.01
4.32
1.3
1.1
—
—
—
0
0
8
9
8.98
4.29
1.3
1.6
—
—
—
0
0
15
39
3.91
4.21
1.5
3.2
22.50
39.41
%
—
6
28
14
35
4.06
4.12
1.1
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
8
10
8.08
4.07
1.3
1.1
125.25
98.80
%
—
8
10
11
23
4.84
3.88
1.1
1.2
—
—
—
0
0
119
836
1.52
3.88
1.3
1.3
28.82
41.76
iu/ml
0.91
46
263
12
28
4.34
3.83
1.3
2.2
—
—
—
0
0
12
28
4.34
3.83
2.4
2.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
11
24
4.64
3.75
1.2
1.3
—
—
—
0
0
540
4955
1.47
3.74
5.0
4.0
1.32
1.25
mmol/l
1.48
494
4415
14
45
3.16
3.67
1.9
1.5
—
—
—
0
0
9
16
5.69
3.67
2.0
1.2
—
—
—
0
0
11
25
4.46
3.63
1.5
1.8
507.00
1521.28
u/ml
1.26
11
25
7
9
7.85
3.56
1.1
1.7
105.86
91.33
%
—
7
9
489
4433
1.39
3.41
41.6
16.7
15.53
15.51
%
0.03
483
4340
19
76
2.54
3.40
1.6
1.3
—
—
—
0
0
12
32
3.80
3.40
1.6
1.4
—
—
—
0
0
13
42
3.14
3.38
1.2
1.1
—
—
—
0
0
12
33
3.68
3.30
1.6
1.4
—
—
—
0
0
539
4980
1.43
3.27
6.5
5.7
39.81
39.74
mmol/mol
0.06
499
4527
13
39
3.38
3.24
1.5
1.4
—
—
—
0
0
29
144
2.06
3.20
1.4
1.4
439.48
273.04
ug/g
0.41
21
94
7
11
6.42
3.19
1.1
1.2
—
—
—
0
0
20
85
2.39
3.18
1.8
1.4
—
—
—
0
0
32
167
1.96
3.10
1.9
1.9
—
—
—
0
0
8
16
5.05
3.06
1.0
1.3
—
—
—
0
0
13
45
2.93
3.04
1.1
1.0
632.23
289.07
ng/l
1.61
13
27
25
120
2.13
3.02
1.8
1.3
—
—
—
0
0
5
5
10.06
2.98
1.8
1.2
121.80
91.40
ng/l
—
5
5
20
88
2.31
2.96
1.6
1.4
—
—
—
0
0
13
46
2.86
2.93
1.1
1.1
1.92
1.54
g/l
1.71
13
41
11
32
3.48
2.91
1.0
1.3
—
—
—
0
0
28
144
1.99
2.84
2.2
3.0
0.91
0.85
nmol/l
0.21
16
113
588
5557
1.49
2.83
40.2
16.4
138.95
139.76
mmol/l
9.16
579
5383
11
33
3.37
2.82
1.2
1.3
—
—
—
0
0
589
5574
1.48
2.75
42.0
16.5
4.03
3.99
mmol/l
2.53
577
5395
17
72
2.40
2.74
2.8
1.6
203.18
253.94
mu/l
0.76
17
63
19
85
2.27
2.72
1.1
1.1
—
—
—
0
0
9
24
3.79
2.68
1.1
1.2
—
—
—
0
0
48
298
1.66
2.68
3.8
2.5
0.24
0.31
e6/l
0.34
48
290
14
55
2.58
2.63
1.1
1.1
—
—
—
0
0
17
74
2.33
2.60
1.7
1.3
—
—
—
0
0
552
5178
1.38
2.57
5.6
4.5
4.40
4.61
mmol/l
5.15
512
4685
548
5136
1.38
2.56
5.5
4.4
1.40
1.48
mmol/l
4.72
506
4608
6
11
5.49
2.55
1.0
1.0
—
—
—
0
0
17
75
2.30
2.53
1.8
1.3
—
—
—
0
0
17
75
2.30
2.53
1.7
1.3
—
—
—
0
0
9
26
3.49
2.49
1.3
1.1
77.89
89.73
u/l
—
9
26
8
21
3.84
2.47
1.6
1.4
60.59
54.32
ug/l
—
8
21
12
45
2.70
2.46
1.1
1.0
43.58
42.84
ng/l
0.02
12
26
12
45
2.70
2.46
1.1
1.0
634.92
620.23
ng/l
0.03
12
26
17
76
2.27
2.46
1.8
1.3
—
—
—
0
0
17
76
2.27
2.46
1.7
1.3
—
—
—
0
0
154
1229
1.33
2.41
1.7
1.7
52800469.02
11111546.14
pmol/l
0.36
125
990
30
168
1.82
2.40
1.7
1.5
0.09
0.09
iu/ml
—
8
31
8
23
3.51
2.27
1.0
1.0
—
—
—
0
0
173
1421
1.29
2.18
1.8
1.6
1.36
1.29
mmol/l
0.50
153
1141
10
37
2.73
2.07
1.2
1.5
—
—
—
0
0
10
37
2.73
2.07
1.2
1.5
—
—
—
0
0
6
15
4.03
2.04
5.8
2.8
216.00
203.13
u/l
—
6
15
14
63
2.25
2.02
1.2
1.5
—
—
—
0
0
5
11
4.57
1.94
1.0
1.2
—
—
—
0
0
124
992
1.31
1.90
1.2
1.2
3.47
1.99
u/ml
0.22
19
243
103
803
1.33
1.89
1.2
1.3
44.69
14.30
u/ml
0.90
27
303
8
29
2.78
1.79
2.5
2.5
—
—
—
0
0
557
5307
1.30
1.75
6.1
5.0
2.54
2.71
mmol/l
3.99
518
4766
79
599
1.36
1.74
1.3
1.4
—
—
—
0
0
5
13
3.87
1.72
1.0
1.2
—
—
—
0
0
25
151
1.68
1.62
1.3
1.2
—
—
—
0
0
60
442
1.39
1.59
1.8
1.9
1.49
1.52
%
0.24
46
374
6
23
2.62
1.37
1.0
1.1
—
—
—
0
0
251
2246
1.19
1.36
4.9
5.4
2.25
3.33
ug/l
1.52
222
1984
5
18
2.79
1.28
2.4
2.6
42680.00
36383.33
ug/l
—
5
18
6
25
2.41
1.24
1.0
1.0
—
—
—
0
0
6
25
2.41
1.24
2.8
3.2
—
—
—
0
0
23
148
1.57
1.21
1.5
1.6
4.10
3.10
mg/l
0.21
18
112
92
753
1.26
1.21
4.6
4.5
34.08
32.41
%
0.79
79
488
8
38
2.12
1.18
1.1
1.1
—
—
—
0
0
8
38
2.12
1.18
1.1
1.1
—
—
—
0
0
78
629
1.27
1.16
2.6
4.3
3.92
34.27
ug/l
1.61
63
533
8
39
2.06
1.15
1.1
1.1
—
—
—
0
0
8
39
2.06
1.15
1.1
1.1
—
—
—
0
0
8
39
2.06
1.15
1.1
1.1
—
—
—
0
0
5
20
2.51
1.15
1.0
1.1
—
—
—
0
0
5
20
2.51
1.15
1.0
1.0
—
—
—
0
0
5
21
2.39
1.09
1.2
1.1
—
—
—
0
0
5
21
2.39
1.09
1.2
1.1
—
—
—
0
0
522
5016
1.19
1.05
31.2
13.3
67.24
75.86
ml/min/173m2
12.41
473
4177
166
1473
1.17
0.97
6.1
4.0
0.00
0.00
estimate
-0.00
67
479
17
110
1.56
0.91
1.3
1.2
—
—
—
0
0
577
5613
1.21
0.91
21.9
10.4
24.07
24.71
u/l
0.67
560
5349
19
130
1.48
0.81
2.2
2.4
171.78
93.70
ug/min
—
9
73
10
58
1.74
0.80
2.3
2.8
15.64
2.92
nmol/l
—
10
58
6
33
1.83
0.79
3.8
3.1
—
—
—
0
0
8
48
1.67
0.79
1.1
1.1
—
—
—
0
0
536
5207
1.15
0.73
5.6
4.8
5.93
5.96
mmol/l
0.17
489
4620
6
109
0.55
0.72
1.8
1.4
—
—
—
0
0
220
2033
1.12
0.71
5.7
4.0
—
—
—
0
0
5
26
1.93
0.70
2.6
1.8
—
—
—
0
0
591
5787
1.19
0.70
49.9
21.1
241.53
241.58
e9/l
0.01
580
5604
591
5787
1.19
0.70
49.8
21.2
38.64
39.85
%
4.87
542
5321
591
5789
1.18
0.69
49.8
21.1
4.26
4.45
e12/l
14.65
576
5582
591
5791
1.18
0.67
50.2
21.2
128.29
134.58
g/l
17.94
584
5661
8
52
1.54
0.59
1.6
1.6
—
—
—
0
0
49
580
0.83
0.58
1.6
1.4
—
—
—
0
0
9
61
1.48
0.54
3.7
4.0
—
—
—
0
0
16
118
1.36
0.50
1.1
1.1
—
—
—
0
0
16
119
1.35
0.48
1.1
1.2
—
—
—
0
0
32
263
1.23
0.48
1.1
1.3
120.86
179.69
u/ml
0.66
32
239
8
117
0.68
0.46
1.1
1.7
—
—
—
0
0
10
69
1.46
0.44
1.0
1.0
—
—
—
0
0
7
51
1.38
0.44
2.3
2.2
—
—
—
0
0
141
1309
1.10
0.42
3.3
3.2
0.72
0.78
ug/l
0.53
106
948
17
132
1.30
0.40
1.8
1.7
—
—
—
0
0
18
141
1.28
0.40
1.3
1.2
—
—
—
0
0
18
141
1.28
0.40
1.3
1.2
—
—
—
0
0
192
1816
1.08
0.38
4.3
4.6
21.51
21.54
%
0.01
98
987
23
273
0.84
0.32
1.2
1.2
32.10
139.04
iu/ml
—
7
115
12
92
1.31
0.32
1.3
1.6
2.50
4.70
iu/l
—
6
24
7
53
1.32
0.31
1.1
1.3
—
—
—
0
0
22
186
1.19
0.28
1.8
1.7
—
—
—
0
0
28
322
0.86
0.28
1.9
1.8
—
—
—
0
0
24
205
1.18
0.27
1.6
1.7
—
—
—
0
0
8
65
1.23
0.27
1.6
1.5
—
—
—
0
0
17
141
1.21
0.26
1.1
1.2
—
2.27
—
0
16
17
142
1.20
0.25
1.1
1.2
28.00
3.47
u/ml
—
5
22
11
87
1.27
0.24
1.0
1.1
—
—
—
0
0
14
115
1.22
0.23
1.1
1.2
—
1.64
—
0
10
5
39
1.28
0.23
1.2
1.3
—
—
—
0
0
5
39
1.28
0.23
1.2
1.3
—
—
—
0
0
5
39
1.28
0.23
1.2
1.5
0.27
0.23
nmol/l
—
5
26
5
42
1.19
0.21
1.0
1.2
—
1.54
—
0
22
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
14
117
1.20
0.20
1.2
1.8
43.57
44.21
nmol/l
0.03
14
110
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
0
14
0.00
0.20
0.0
2.2
—
—
—
0
0
120
1150
1.05
0.18
5.5
4.2
1.02
1.02
kg/l
0.53
24
173
17
148
1.15
0.17
1.1
1.2
—
1.07
—
0
7
22
201
1.10
0.11
1.4
1.3
—
—
—
0
0
73
754
0.96
0.08
11.4
7.0
—
—
—
0
0
7
68
1.03
0.08
1.6
1.7
—
—
—
0
0
27
261
1.04
0.02
1.7
3.5
40.81
84.89
u/ml
1.02
27
251
11
105
1.05
0.00
1.1
1.2
—
30.71
—
0
9
12
124
0.97
0.00
1.7
1.3
—
—
—
0
0
21
206
1.02
0.00
1.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
8.11
—
0
9
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
8
82
0.98
-0.00
2.5
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
6
65
0.92
-0.00
1.2
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint E4_AMYLNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_AMYLNAS | 5.481 [4.42, 6.8] | < 0.001 |
| Birth year | 0.998 [0.99, 1.01] | 0.681 |
During the follow-up period (1.1.1998 — 31.12.2019), 696 out of 1370 females with E4_AMYLNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_AMYLNAS | 4.06 [3.17, 5.2] | < 0.001 |
| Birth year | 0.985 [0.97, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 668 out of 1241 males with E4_AMYLNAS died.
Mortality risk
Mortality risk for people of age
years, who have E4_AMYLNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.4% | 0.707% |
| 5 | 3.508% | 4.19% |
| 10 | 8.544% | 10.612% |
| 15 | 15.418% | 19.136% |
| 20 | 27.346% | 30.589% |
Relationships between endpoints
↥Index endpoint: E4_AMYLNAS – Amyloidosis, other/unspecified
GWS hits: 12
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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