Neuroendocrine tumor and carcinoma of lung

C3_LUNG_NEUROENDO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cancer registry: Topography ICD-O-3 C34
  • Cancer registry: Morphology ICD-O-3 8240|8246|8249
  • Cancer registry: Behaviour codes 3

1 out of 7 registries used, show all original rules.

282

4. Check minimum number of events

None

282

5. Include endpoints

None

282

6. Filter based on genotype QC (FinnGen only)

277

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF9

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 277 177 100
Unadjusted period prevalence (%) 0.06 0.06 0.05
Median age at first event (years) 65.23 64.63 66.28

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
282
Matched controls
2820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
265.9
312.5
150
12
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
30.2
193.0
168
131
UGC12
NOMESCO Finland
Flexible bronchoscopy
24.1
142.0
120
84
C34.17
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary carcinoid
+∞
89.4
81
*
130
Kela drug reimbursment
Malignant tumour
+∞
84.8
77
*
C34.37
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung carcinoid
+∞
81.3
74
*
H02AB02
ATC
dexamethasone; systemic
45.4
80.8
49
13
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
+∞
80.1
73
*
8240/3-C34.9
ICD-O-3
Neuroendocrine tumor, NOS, of lung, NOS
+∞
70.9
65
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
25.1
67.9
50
24
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
12.6
60.2
66
67
JN4BD
NOMESCO Finland
Extensive body CT
14.1
58.8
59
52
WZC30
NOMESCO Finland
Teaching
7.9
56.6
100
184
8240/3-C34.3
ICD-O-3
Neuroendocrine tumor, NOS, of lower lobe, lung
+∞
53.9
50
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
6.8
52.2
111
245
GDC00
NOMESCO Finland
Lobectomy of lung
+∞
48.3
45
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.4
45.6
213
914
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
115.2
45.4
48
5
8240/3-C34.1
ICD-O-3
Neuroendocrine tumor, NOS, of upper lobe, lung
+∞
45.0
42
*
A04AA01
ATC
ondansetron; systemic, rectal
15.9
44.2
40
29
GD1AD
NOMESCO Finland
Thorax CT examination
10.6
42.0
50
56
C34.27
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung carcinoid
+∞
39.5
37
*
ZXE20
NOMESCO Finland
More than three and less than five hours
5.9
37.0
83
187
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
9.4
35.7
46
57
A03FA01
ATC
metoclopramide; systemic, rectal
5.1
33.0
88
229
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
33.0
31
*
JN4AD
NOMESCO Finland
Body CT examination
8.2
32.4
47
67
Z51.5
ICD-10 Finland
Palliative care
11.6
32.2
35
34
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
31.9
30
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
29.7
28
*
R4110
NOMESCO Finland
Physiotherapy
4.1
29.1
125
462
8246/3-C34.9
ICD-O-3
Neuroendocrine carcinoma, NOS, of lung, NOS
+∞
28.6
27
*
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
+∞
27.5
26
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
27.5
26
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
83.3
27.4
30
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
298.0
27.2
27
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
7.7
26.6
40
59
XX3DW
NOMESCO Finland
Time consuming IT work
7.3
26.4
42
66
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
8.5
26.1
36
48
WX402
NOMESCO Finland
General anaesthesia
4.3
25.5
85
259
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
99.2
25.1
27
*
PJA12
NOMESCO Finland
Sentinel node biopsy
273.2
25.1
25
*
8240/3-C34.2
ICD-O-3
Neuroendocrine tumor, NOS, of middle lobe, lung
+∞
24.3
23
*
C34.97
ICD-10 Finland
Malignant tumor in unspecified location in bronchial and pulmonary carcinoid
+∞
24.3
23
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
24.3
23
*
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
23.2
22
*
B01AB05
ATC
enoxaparin; parenteral
3.4
22.0
131
578
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
7.7
21.7
32
46
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
21.1
20
*
115
Kela drug reimbursment
Breast cancer
+∞
21.1
20
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
20.1
98
380
L01CB01
ATC
etoposide; systemic
+∞
20.0
19
*
L01BC06
ATC
capecitabine; oral
+∞
20.0
19
*
JN4CD
NOMESCO Finland
Very extensive body CT
23.8
19.9
28
13
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
43.6
19.8
24
6
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.7
19.7
79
269
N03AX16
ATC
[U] pregabalin
3.3
19.3
107
446
TPH07
NOMESCO Finland
Cathetrisation of artery
4.3
18.6
54
146
ZXE10
NOMESCO Finland
More than one and less than three hours
3.0
18.1
135
662
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
71.4
18.0
20
*
8246/3-C34.1
ICD-O-3
Neuroendocrine carcinoma, NOS, of upper lobe, lung
+∞
17.9
17
*
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
+∞
17.9
17
*
R84
ICPC
Malignant neoplasm bronchus/lung
191.5
17.7
18
*
B01AB04
ATC
dalteparin; parenteral
6.8
17.6
29
47
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
67.6
17.0
19
*
L03AA13
ATC
pegfilgrastim; parenteral
95.9
16.8
18
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.2
16.4
49
135
L01AX03
ATC
temozolomide; systemic
+∞
15.8
15
*
8249/3-C34.3
ICD-O-3
Neuroendocrine tumor, grade 2 of lower lobe, lung
+∞
15.8
15
*
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
+∞
15.8
15
*
H01CB03
ATC
lanreotide; parenteral
+∞
15.8
15
*
L02BG04
ATC
letrozole; oral
90.2
15.7
17
*
WF002
NOMESCO Finland
Radical radiotherapy
47.8
15.2
18
*
N02AX02
ATC
tramadol; systemic, rectal
2.7
14.9
158
905
8249/3-C34.1
ICD-O-3
Neuroendocrine tumor, grade 2 of upper lobe, lung
+∞
14.7
14
*
C34.87
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary carcinoid
+∞
14.7
14
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
10.9
14.3
27
27
N02AA05
ATC
oxycodone; systemic
3.3
13.9
61
217
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
6.9
13.9
22
34
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
13.6
13
*
C34.39
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung other or unspecified histology
+∞
13.6
13
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
5.1
13.6
30
64
HAB40
NOMESCO Finland
Wedge excision of mammary gland
42.3
13.3
16
*
TGD00
NOMESCO Finland
Needle biopsy of lung
73.2
12.7
14
*
R03BB04
ATC
tiotropium bromide; inhalant
3.4
12.6
52
177
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
+∞
12.6
12
*
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
+∞
12.6
12
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
12.6
12
*
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
12.6
12
*
R04.2
ICD-10 Finland
Haemoptysis
6.2
12.5
22
38
WZC00
NOMESCO Finland
Treatment plan or consultation
2.6
11.9
97
478
ZXD10
NOMESCO Finland
Scheduled procedure
2.4
11.7
129
730
ZX090
NOMESCO Finland
Other technic of radiotherapy
67.9
11.7
13
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
11.5
11
*
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
+∞
11.5
11
*
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
+∞
11.5
11
*
E34.0
ICD-10 Finland
Carcinoid syndrome
+∞
11.5
11
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
11.5
11
*
C34.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bronchus and lung
+∞
11.5
11
*
C34.07
ICD-10 Finland
Malignant tumor of the main bronchus carcinoid
+∞
11.5
11
*
C50.99
ICD-10 Finland
Breast, unspecified
+∞
11.5
11
*
D14.3
ICD-10 Finland
Benign neoplasm: Bronchus and lung
124.9
11.5
12
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
26.3
11.3
15
6
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
9.4
11.0
22
25
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
62.4
10.7
12
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.2
10.6
47
167
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
+∞
10.5
10
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
10.5
10
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
10.5
10
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
10.5
10
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
10.5
10
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
10.5
10
*
Z2221
NOMESCO Finland
Medical doctor
2.4
10.4
90
453
R03AK08
ATC
formoterol and beclometasone; inhalant
4.6
10.3
25
58
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.4
10.0
93
482
Z3226
NOMESCO Finland
Physiotherapist
2.6
9.7
67
302
ZXE00
NOMESCO Finland
One hour or less
2.2
9.6
122
719
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
9.5
23
53
XG410
NOMESCO Finland
Flow-volume spirometry
4.8
9.5
22
49
H01CB02
ATC
octreotide; parenteral
103.4
9.5
10
*
L02BA01
ATC
tamoxifen; oral
103.4
9.5
10
*
A79
ICPC
Malignancy NOS
+∞
9.4
9
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
9.4
9
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
9.4
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
9.4
9
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
9.4
9
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
9.4
9
*
C34.00
ICD-10 Finland
Malignant tumor of the main bronchus without histology
+∞
9.4
9
*
ZXA00
NOMESCO Finland
Right side
2.3
9.4
95
509
R03AC02
ATC
salbutamol; inhalant
2.2
9.2
179
1241
HA1AA
NOMESCO Finland
X-ray mammography
4.9
9.2
21
46
A02BC02
ATC
pantoprazole; systemic
2.3
8.9
209
1556
ZX070
NOMESCO Finland
Intensity modified radiotherapy
92.7
8.5
9
*
WX250
NOMESCO Finland
Intercostal blockade
92.7
8.5
9
*
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
92.7
8.5
9
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
92.7
8.5
9
*
WX892
NOMESCO Finland
Monitored bed care
3.4
8.4
32
103
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
+∞
8.4
8
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
8.4
8
*
C34.20
ICD-10 Finland
Malignant tumor of the middle lobe, bronchus or lung without histology
+∞
8.4
8
*
GDC20
NOMESCO Finland
Lobectomy of lung and sleeve resection of bronchus
+∞
8.4
8
*
C34.15
ICD-10 Finland
Malignant tumor of the anterior, bronchial or lung other non-microcellular carcinoma
+∞
8.4
8
*
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
46.3
7.8
9
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
46.3
7.8
9
*
J01MA14
ATC
moxifloxacin; systemic
3.0
7.7
35
126
ZXE30
NOMESCO Finland
More than five and less than seven hours
6.3
7.5
19
32
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
6.1
7.4
19
33
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
7.3
7
*
GCA05
NOMESCO Finland
Bronchoscopic laser therapy of lesion of bronchus
+∞
7.3
7
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
7.3
7
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
7.3
7
*
C50.91
ICD-10 Finland
Malignant tumor in another specified localization in ductal mammary gland
+∞
7.3
7
*
PJD99
NOMESCO Finland
Excision of other lymph nodes
+∞
7.3
7
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
7.3
7
*
A04AD12
ATC
aprepitant; systemic
+∞
7.3
7
*
8246/3-C34.3
ICD-O-3
Neuroendocrine carcinoma, NOS, of lower lobe, lung
+∞
7.3
7
*
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
+∞
7.3
7
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.1
7.3
31
107
WX600
NOMESCO Finland
Single shot through catheter
30.9
7.2
9
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
8.6
6.9
14
17
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
9.7
6.9
13
14
ZXC96
NOMESCO Finland
Robot assisted procedure
17.2
6.8
10
6
GDA20
NOMESCO Finland
Excision of lesion of lung
41.1
6.8
8
*
J01MA12
ATC
levofloxacin; systemic
2.3
6.7
59
293
R52.0
ICD-10 Finland
Acute pain
4.2
6.7
18
45
WX110
NOMESCO Finland
Infiltration anesthesia
2.0
6.7
195
1489
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
10.4
6.6
12
12
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.6
6.5
41
175
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
71.4
6.5
7
*
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
71.4
6.5
7
*
HAE10
NOMESCO Finland
Reconstruction of breast using graft or flap
71.4
6.5
7
*
Z72.0
ICD-10 Finland
Tobacco use
6.8
6.4
15
23
JN3AD
NOMESCO Finland
Abdominal CT examination
2.7
6.3
37
152
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
5.3
6.3
18
36
8249/3-C34.2
ICD-O-3
Neuroendocrine tumor, grade 2 of middle lobe, lung
+∞
6.3
6
*
C77.1
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Intrathoracic lymph nodes
+∞
6.3
6
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*
GDB20
NOMESCO Finland
Segmental resection of lung
+∞
6.3
6
*
J93.8
ICD-10 Finland
Other pneumothorax
+∞
6.3
6
*
C34.16
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary microcellular carcinoma
+∞
6.3
6
*
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
+∞
6.3
6
*
C50
ICD-10 Finland
Malignant neoplasm of breast
+∞
6.3
6
*
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
6.3
6
*
GDC10
NOMESCO Finland
Bilobectomy of lung
+∞
6.3
6
*
116
Kela drug reimbursment
Prostate cancer
+∞
6.3
6
*
XX7JT
NOMESCO Finland
Somatostatin isotope ablative therapy
+∞
6.3
6
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
6.3
60
309
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.0
6.2
13
17
H02AB06
ATC
prednisolone; systemic
1.9
6.2
144
1011
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
6.1
65
349
B01AB10
ATC
tinzaparin; parenteral
2.8
6.0
31
119

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
113
60
30.76
152.15
1.5
1.3
—
—
—
0
0
97
156
8.95
62.41
1.5
1.1
—
—
—
0
0
72
115
8.06
45.67
2.6
1.4
24.14
2.61
ug/l
0.50
61
92
166
727
4.12
30.54
3.2
1.6
—
—
—
0
0
216
1198
4.43
26.96
10.3
6.0
4.16
4.16
e9/l
0.00
192
1049
201
1071
4.05
26.35
9.9
13.6
1.14
1.29
inr
1.71
48
311
139
587
3.70
25.97
2.8
1.9
—
—
—
0
0
140
651
3.28
21.46
4.7
2.9
7.40
7.40
ph
0.09
28
115
178
962
3.31
20.96
6.5
5.4
0.70
0.71
%
0.06
173
889
110
453
3.34
20.47
2.5
1.9
—
—
—
0
0
45
97
5.33
20.43
11.4
12.7
—
—
—
0
0
75
242
3.86
20.34
8.2
8.0
1.37
1.29
mmol/l
0.07
70
200
182
1011
3.26
20.17
6.5
5.6
8.88
8.43
%
1.36
177
940
181
1006
3.23
19.97
6.4
5.2
2.65
3.00
%
1.64
176
933
168
906
3.11
19.33
4.8
3.5
35.17
35.88
g/l
0.87
161
832
179
1002
3.15
19.24
7.9
5.1
1.22
1.22
mmol/l
0.03
172
897
182
1029
3.17
19.21
6.5
5.4
26.26
28.24
%
1.69
176
960
188
1085
3.20
19.10
6.3
5.1
0.60
0.57
e9/l
0.79
162
941
190
1104
3.21
19.05
6.3
5.2
1.79
1.87
e9/l
0.61
165
977
188
1091
3.17
18.79
6.3
5.1
0.04
0.04
e9/l
0.14
162
949
55
153
4.22
18.20
10.8
6.7
—
—
—
0
0
210
1313
3.35
18.16
6.4
4.4
6.99
6.74
mmol/l
0.95
202
1215
190
1128
3.10
17.88
6.4
5.4
0.19
0.20
e9/l
0.14
166
986
167
928
2.96
17.67
2.7
2.2
—
—
—
0
0
178
1024
3.00
17.66
7.3
5.6
—
—
—
0
0
186
1101
3.03
17.41
9.0
5.5
1.21
1.22
mmol/l
0.82
161
945
177
1022
2.97
17.32
6.3
5.2
58.78
57.03
%
1.12
172
954
109
492
2.98
16.77
6.7
4.3
—
—
—
0
0
240
1728
3.61
14.41
13.0
5.2
84.75
75.38
u/l
2.44
235
1589
163
968
2.62
14.02
11.6
8.2
0.00
0.00
e9/l
0.48
125
790
131
706
2.60
13.72
4.8
2.0
2.39
2.35
mmol/l
2.24
120
575
56
192
3.39
13.49
1.6
1.4
—
—
—
0
0
23
24
10.33
11.99
2.1
3.0
—
—
—
0
0
105
544
2.48
11.55
4.8
3.5
—
—
—
0
0
14
9
16.28
9.13
1.0
1.0
—
—
—
0
0
51
210
2.74
8.77
1.5
1.5
—
—
—
0
0
42
167
2.78
7.68
4.5
6.6
8.31
10.78
mmol/l
1.73
42
157
76
403
2.21
7.48
3.8
2.0
2.49
2.44
mmol/l
2.61
70
335
15
18
8.73
7.42
3.2
1.6
—
—
—
0
0
54
256
2.37
6.87
3.3
4.6
1.00
1.04
mmol/l
0.60
54
231
103
632
1.99
6.80
3.5
2.8
25.14
174.46
e6/l
0.81
78
481
92
557
1.97
6.22
3.4
2.6
—
—
—
0
0
11
12
9.48
5.84
1.2
1.3
—
—
—
0
0
114
757
1.85
5.73
4.0
3.4
92.83
84.71
e6/l
0.06
84
522
5
0
+∞
5.22
1.2
0.0
165.80
—
ng/l
—
5
0
91
578
1.85
5.18
3.5
2.8
0.60
0.45
e6/l
0.27
65
428
208
1688
1.88
5.17
4.4
3.9
—
—
—
0
0
80
491
1.88
5.06
1.2
1.3
—
—
—
0
0
58
326
1.98
4.74
3.1
2.8
2.32
3.33
e6/l
0.23
29
172
18
59
3.19
4.60
1.2
1.7
139.14
132.90
g/l
—
7
41
9
12
7.70
4.39
1.2
1.1
—
—
—
0
0
207
1722
1.76
4.22
4.9
4.3
14.93
11.92
mm/h
1.71
197
1555
33
156
2.26
4.20
3.2
4.3
0.09
0.07
%
0.08
11
29
10
17
6.06
4.16
1.3
1.1
—
—
—
0
0
14
35
4.15
4.16
2.9
3.3
—
—
—
0
0
8
10
8.19
4.08
1.1
1.0
—
—
—
0
0
75
482
1.76
3.99
1.7
1.6
1.77
0.97
mg/l
1.18
63
376
32
154
2.22
3.91
3.3
4.2
0.00
0.04
%
—
10
27
33
163
2.16
3.79
3.2
4.1
0.64
0.78
%
0.16
11
36
52
304
1.87
3.75
2.1
1.9
—
—
—
0
0
8
12
6.82
3.70
1.3
1.0
—
—
—
0
0
15
53
2.93
3.41
1.5
1.9
4.72
4.71
mmol/24h
0.00
15
47
13
38
3.54
3.36
2.8
3.0
3.74
4.76
e9/l
0.92
13
38
13
38
3.54
3.36
3.3
3.6
56.15
61.00
%
0.77
13
38
30
150
2.12
3.35
3.2
4.1
0.22
0.22
%
—
9
32
34
181
2.00
3.22
1.6
1.9
77.60
66.56
e9/l
0.65
23
140
33
175
2.00
3.16
2.2
3.6
103.24
77.87
ng/l
1.48
33
156
251
2274
1.94
3.11
24.5
11.7
32.69
21.73
mg/l
4.53
238
1722
222
1946
1.66
3.05
30.1
13.7
14.92
15.06
%
0.14
222
1909
7
12
5.95
3.04
1.4
1.1
—
—
—
0
0
10
26
3.95
3.01
1.1
1.6
92.04
89.12
%
—
10
26
15
59
2.63
2.83
2.8
2.8
7.44
7.42
ph
0.95
15
51
65
445
1.60
2.65
2.9
2.1
8.35
7.50
e6/l
0.13
60
401
8
22
3.71
2.38
1.3
1.1
—
—
—
0
0
65
457
1.55
2.35
3.8
3.9
1311.21
225.97
ng/l
0.71
52
366
13
56
2.39
2.08
2.5
2.8
—
—
—
0
0
5
10
5.07
2.08
1.8
2.5
—
—
—
0
0
6
15
4.06
2.05
1.2
1.0
—
—
—
0
0
6
15
4.06
2.05
2.2
1.4
—
—
—
0
0
11
45
2.50
1.95
1.1
1.3
139.18
65.50
pmol/l
0.79
11
45
6
16
3.81
1.94
2.0
1.3
—
—
—
0
0
7
22
3.24
1.89
1.4
1.5
—
—
—
0
0
11
46
2.45
1.87
2.0
3.3
—
—
—
0
0
35
227
1.62
1.78
1.3
1.3
—
—
—
0
0
5
13
3.89
1.72
2.2
1.8
—
—
—
0
0
29
182
1.66
1.68
4.3
3.4
—
—
—
0
0
8
32
2.54
1.61
1.1
1.3
—
—
—
0
0
9
38
2.41
1.47
1.9
1.9
59.11
64.77
%
—
9
38
9
38
2.41
1.47
1.0
1.3
—
—
—
0
0
9
38
2.41
1.47
1.3
1.4
—
—
—
0
0
9
38
2.41
1.47
1.3
1.4
—
—
—
0
0
9
38
2.41
1.47
1.3
1.4
—
—
—
0
0
5
16
3.16
1.44
3.0
1.5
1.10
1.03
g/l
—
5
16
5
16
3.16
1.44
1.2
2.1
—
2.00
—
0
9
9
39
2.35
1.44
1.3
1.4
—
—
—
0
0
6
22
2.76
1.44
1.2
1.4
—
—
—
0
0
9
41
2.23
1.38
1.0
1.0
—
—
—
0
0
24
154
1.61
1.31
1.5
1.3
—
—
—
0
0
11
55
2.04
1.29
2.5
1.5
0.89
0.90
nmol/l
0.02
11
43
9
45
2.03
1.24
1.7
2.6
—
—
—
0
0
8
37
2.20
1.22
1.4
1.4
—
—
—
0
0
8
38
2.14
1.19
1.1
1.1
—
—
—
0
0
6
26
2.34
1.19
1.3
1.4
—
—
—
0
0
223
2357
0.74
1.19
4.5
4.8
1.41
1.52
mmol/l
3.28
209
2153
0
33
0.00
1.17
0.0
1.2
—
—
—
0
0
5
20
2.53
1.15
1.0
1.1
—
—
—
0
0
231
2427
0.73
1.15
5.0
5.4
2.59
2.77
mmol/l
2.28
215
2219
215
2280
0.76
1.13
4.0
4.3
1.42
1.28
mmol/l
2.08
196
2061
71
578
1.31
1.11
2.4
2.2
4045.40
10880.38
umol/l
0.83
60
492
5
21
2.41
1.09
1.0
1.2
—
—
—
0
0
37
275
1.40
1.04
1.5
1.5
—
—
—
0
0
34
249
1.42
1.04
1.2
1.6
—
—
—
0
0
226
2373
0.76
1.01
4.5
4.8
4.50
4.71
mmol/l
2.33
213
2181
15
92
1.67
0.99
4.3
3.3
—
—
—
0
0
6
27
2.25
0.94
1.0
1.2
—
—
—
0
0
6
27
2.25
0.94
1.5
1.3
—
—
—
0
0
6
30
2.02
0.87
1.3
1.5
—
—
—
0
0
8
44
1.84
0.86
1.9
1.3
—
—
—
0
0
8
45
1.80
0.85
1.1
1.6
—
—
—
0
0
83
713
1.23
0.83
2.9
3.0
—
—
—
0
0
6
32
1.89
0.82
1.2
1.3
—
—
—
0
0
0
26
0.00
0.79
0.0
1.6
—
—
—
0
0
19
134
1.45
0.73
4.0
3.1
5.22
5.25
kpa
0.05
19
129
10
60
1.69
0.73
1.7
1.6
—
—
—
0
0
107
957
1.19
0.70
3.4
3.6
20.25
37.43
ng/l
2.51
76
679
25
188
1.36
0.69
1.2
1.5
—
—
—
0
0
167
1556
1.18
0.67
4.0
4.1
—
—
—
0
0
126
1148
1.18
0.66
3.3
3.6
0.00
0.02
estimate
0.50
24
193
20
146
1.40
0.66
4.5
8.2
—
—
—
0
0
7
44
1.61
0.65
1.3
1.1
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
31
247
1.29
0.60
1.4
1.6
—
—
—
0
0
124
1136
1.16
0.59
4.4
4.9
0.00
0.00
estimate
-0.00
26
195
76
670
1.18
0.58
1.6
1.7
1.46
1.36
mmol/l
0.49
67
570
12
81
1.50
0.58
1.2
1.2
—
—
—
0
0
5
86
0.57
0.57
2.0
1.6
—
—
—
0
0
6
37
1.63
0.56
2.2
2.1
—
—
—
0
0
12
170
0.69
0.55
1.1
1.2
—
—
—
0
0
122
1125
1.15
0.52
3.4
3.6
0.00
0.00
estimate
0.50
26
214
18
135
1.36
0.52
1.9
3.4
—
—
—
0
0
192
1828
1.16
0.52
4.1
4.0
14.67
14.93
pmol/l
0.74
178
1643
12
165
0.72
0.48
2.0
2.6
—
—
—
0
0
40
339
1.21
0.47
1.5
1.2
—
—
—
0
0
54
615
0.85
0.47
3.7
3.9
1.50
2.07
ug/l
1.75
46
544
48
416
1.19
0.45
1.2
1.3
41.76
46.49
iu/ml
0.08
13
134
12
86
1.41
0.45
1.3
1.6
1.70
1.65
g/l
0.06
12
76
15
196
0.75
0.44
2.8
2.9
—
—
—
0
0
17
131
1.32
0.43
1.4
1.3
—
—
—
0
0
61
543
1.16
0.42
2.2
2.1
3.80
3.10
mg/l
0.38
52
456
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
3.5
—
30.70
—
0
10
30
355
0.83
0.40
2.5
2.6
0.50
0.75
ug/l
3.09
19
225
10
71
1.42
0.39
1.0
1.1
—
—
—
0
0
17
133
1.30
0.39
1.5
1.5
—
—
—
0
0
51
574
0.86
0.39
1.6
1.5
19.92
21.95
nmol/l
0.48
46
494
11
80
1.39
0.39
4.5
3.7
25.89
25.37
mmol/l
0.19
11
75
41
469
0.85
0.38
1.7
1.7
1166.49
1235.54
nmol/l
0.18
35
348
15
116
1.31
0.38
1.3
1.2
—
—
—
0
0
36
311
1.18
0.36
1.2
1.3
251.43
473.60
titre
—
7
75
6
43
1.40
0.35
1.5
2.5
—
—
—
0
0
6
86
0.69
0.33
21.7
8.8
—
—
—
0
0
86
797
1.11
0.33
2.8
3.1
8.21
7.12
mmol/l
0.83
74
670
155
1482
1.10
0.32
4.5
2.9
67.62
46.14
u/l
1.27
148
1361
49
440
1.14
0.31
1.3
1.3
2.48
2.55
g/l
0.10
27
247
46
512
0.88
0.31
1.3
1.3
1.53
2.45
u/ml
—
6
139
12
152
0.78
0.30
1.2
1.2
97.34
121.57
iu/ml
—
5
67
87
811
1.11
0.30
3.5
3.8
7.94
6.38
mg/mmol
0.20
46
488
21
176
1.21
0.29
1.1
1.2
—
—
—
0
0
66
608
1.11
0.28
4.0
3.7
0.00
0.00
estimate
-0.00
22
193
47
519
0.89
0.28
3.7
3.8
1.02
1.02
kg/l
—
6
77
8
63
1.28
0.28
1.6
2.7
—
—
—
0
0
58
532
1.11
0.27
3.2
3.5
—
—
—
0
0
83
777
1.10
0.26
2.9
3.2
33.25
218.39
mg/l
0.84
46
474
24
208
1.17
0.25
1.2
1.4
—
—
—
0
0
231
2353
0.90
0.25
5.0
4.8
6.24
5.99
mmol/l
2.00
215
2119
104
989
1.08
0.23
1.8
2.0
87.57
98.37
pmol/l
1.71
54
472
216
2204
0.91
0.22
5.0
4.8
1.70
2.49
mu/l
0.80
199
1987
77
725
1.09
0.22
3.0
2.2
65.38
63.52
u/l
0.06
71
669
8
103
0.77
0.21
1.1
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
35.90
—
0
5
0
10
0.00
0.21
0.0
7.0
—
713.10
—
0
10
0
10
0.00
0.21
0.0
14.3
—
1299.10
—
0
10
0
13
0.00
0.21
0.0
1.1
—
3.22
—
0
5
221
2247
0.92
0.18
6.2
6.2
41.32
40.29
mmol/mol
1.06
209
2074
26
234
1.12
0.17
1.3
1.5
—
—
—
0
0
78
743
1.07
0.16
1.8
2.1
124.80
169.45
u/l
1.25
70
691
195
1912
1.06
0.16
31.8
15.7
328.88
331.88
g/l
4.77
195
1896
21
234
0.89
0.15
5.1
3.1
—
—
—
0
0
16
140
1.15
0.15
2.2
2.3
—
—
—
0
0
243
2403
1.08
0.14
20.7
11.6
—
—
—
0
0
65
622
1.06
0.12
3.4
3.2
—
—
—
0
0
88
910
0.95
0.12
3.3
3.4
5.42
5.88
ph
—
6
56
92
943
0.96
0.08
2.3
2.6
127.71
110.17
ug/l
0.43
80
869
11
98
1.13
0.08
1.4
1.8
—
—
—
0
0
7
85
0.82
0.07
1.0
1.1
—
—
—
0
0
254
2553
0.95
0.05
36.1
17.5
40.28
40.33
%
0.07
245
2350
254
2553
0.95
0.05
34.6
17.6
4.46
4.50
e12/l
0.60
249
2456
254
2553
0.95
0.05
34.6
17.6
7.14
6.59
e9/l
3.60
249
2459
74
725
1.03
0.04
4.4
3.8
—
—
—
0
0
18
187
0.96
0.01
2.8
2.5
—
21.95
—
0
10
83
823
1.01
0.01
2.9
3.1
—
—
—
0
0
10
98
1.02
0.00
3.5
4.6
—
—
—
0
0
12
122
0.98
0.00
2.2
2.2
1.01
1.19
%
0.51
12
122
16
162
0.99
0.00
1.2
1.4
—
—
—
0
0
41
412
0.99
0.00
1.1
1.2
5.81
12.70
u/ml
0.62
15
158
12
119
1.01
0.00
2.2
2.1
0.52
0.63
%
1.15
12
119
12
115
1.05
0.00
1.0
1.4
—
—
—
0
0
52
525
0.99
0.00
1.4
1.8
491.63
449.36
pmol/l
0.52
41
425
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
29.33
—
0
9
8
80
1.00
-0.00
1.5
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
7
74
0.94
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
10.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
16.83
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
44.23
—
0
6
15
150
1.00
-0.00
1.4
2.8
4.23
4.78
e9/l
0.27
15
113
7
73
0.96
-0.00
2.7
4.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
1510.78
—
0
9
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
5
53
0.94
-0.00
1.2
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
8.7
—
0.64
—
0
7
0
6
0.00
-0.00
0.0
10.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
8.3
—
24.48
—
0
9
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.7
—
—
—
0
0
7
71
0.99
-0.00
1.0
1.2
—
3.03
—
0
15
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_LUNG_NEUROENDO – Neuroendocrine tumor and carcinoma of lung

GWS hits: 1

This endpoint is excluded from FinRegistry analyses (omitted endpoint).