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Malignant neoplasm of rectosigmoid junction

C3_RECTOSIGMOID_JUNCTION

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C19&
  • Cause of death: ICD-9 1540
  • Cause of death: ICD-8 1540
  • Cancer registry: Topography ICD-O-3 C19
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

541

4. Check minimum number of events

None

541

5. Include endpoints

None

541

6. Filter based on genotype QC (FinnGen only)

541

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 541 197 344
Unadjusted period prevalence (%) 0.12 0.07 0.15
Median age at first event (years) 68.87 66.30 70.34

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
497
Matched controls
4968
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
+∞
323.0
423
*
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
565.6
240.9
221
7
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
73.9
193.0
216
51
L01BC06
ATC
capecitabine; oral
50.4
173.5
210
71
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
86.7
164.1
179
32
130
Kela drug reimbursment
Malignant tumour
19.4
159.3
274
296
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
94.2
136.0
147
22
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
15.2
116.2
213
234
UJF32
NOMESCO Finland
Coloscopy
9.2
111.1
338
933
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
48.9
89.4
108
28
A03FA01
ATC
metoclopramide; systemic, rectal
7.3
82.4
255
630
A04AA02
ATC
granisetron; systemic, transdermal
14.0
77.4
141
137
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.4
74.5
138
138
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
126.5
62.5
66
6
H02AB02
ATC
dexamethasone; systemic
7.4
56.6
152
280
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
12.9
53.0
98
93
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
19.2
51.6
80
49
JN4BD
NOMESCO Finland
Extensive body CT
6.3
51.0
156
338
B01AB05
ATC
enoxaparin; parenteral
4.3
49.8
273
1101
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
29.1
42.2
57
22
JG1BG
NOMESCO Finland
MRI of rectum
73.9
41.8
47
7
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
12.1
39.9
75
72
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
418.8
39.6
39
*
TPH07
NOMESCO Finland
Cathetrisation of artery
5.4
39.2
134
320
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
7.4
38.8
99
162
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
17.2
38.1
61
40
C18.79
ICD-10 Finland
Malignant tumor of the sigmoid or other unspecified histology
44.8
36.9
45
11
C18.7
ICD-10 Finland
Malignant neoplasm: Sigmoid colon
65.3
36.8
42
7
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
105.6
36.3
39
*
WF001
NOMESCO Finland
Preoperative radiotherapy
29.3
35.7
48
18
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
8.5
35.1
80
109
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
42.6
34.9
43
11
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
61.9
34.7
40
7
C20
ICD-10 Finland
Malignant neoplasm of rectum
44.6
33.6
41
10
C20.99
ICD-10 Finland
Malignant tumor of the rectum other or unspecified histology
51.2
32.0
38
8
JFF23
NOMESCO Finland
Transversostomy
24.6
32.0
45
20
JN4AD
NOMESCO Finland
Body CT examination
5.6
30.9
98
210
JGB07
NOMESCO Finland
Laparoscopic partial proctectomy with total excision of mesorectum
110.0
29.0
31
*
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
14.3
27.5
47
36
D75
ICPC
Malignant neoplasm colon/rectum
24.1
26.9
38
17
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.5
26.2
64
96
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
53.0
25.5
30
6
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
12.6
25.5
46
40
UJG02
NOMESCO Finland
Proctoscopy
11.4
25.4
48
46
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
13.7
25.4
44
35
8480/3-C19.9
ICD-O-3
Mucinous adenocarcinoma of rectosigmoid junction
+∞
25.2
24
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
24.6
189
852
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
22.0
24.2
35
17
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
9.2
24.0
51
61
JFB54
NOMESCO Finland
Laparoscopic resection of sigmoid colon with partial proctectomy
91.3
23.9
26
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
23.7
211
1040
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
38.4
23.2
29
8
WZC30
NOMESCO Finland
Teaching
3.6
23.1
116
383
JFB46
NOMESCO Finland
Resection of sigmoid colon
18.7
23.0
35
20
JG1CG
NOMESCO Finland
Extensive MRI of rectum
42.3
22.9
28
7
JFB53
NOMESCO Finland
Resection of sigmoid colon with partial proctectomy
+∞
21.0
20
*
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
18.3
20.3
31
18
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
60.1
20.1
23
*
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
207.9
19.7
20
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
11.7
19.5
36
33
B01AB10
ATC
tinzaparin; parenteral
4.4
19.4
74
189
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
5.1
19.2
63
138
TJF80
NOMESCO Finland
Ostomy education
16.7
19.0
30
19
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.4
19.0
42
54
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
6.4
18.1
48
81
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
7.9
17.8
41
56
WX402
NOMESCO Finland
General anaesthesia
2.9
16.1
108
428
SPAT1125
SPAT
Stoma care and guidance
10.9
15.9
30
29
XX3DW
NOMESCO Finland
Time consuming IT work
3.3
15.9
87
300
Z93
ICD-10 Finland
Artificial opening status
27.3
15.7
21
8
N02AA05
ATC
oxycodone; systemic
2.7
15.4
124
550
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
29.7
15.3
20
7
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.7
15.2
44
83
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
24.3
15.2
21
9
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
58.5
14.9
17
*
JAH00
NOMESCO Finland
Laparotomy
6.2
14.5
39
67
JFF10
NOMESCO Finland
Loop enterostomy
16.4
14.0
22
14
Z51.5
ICD-10 Finland
Palliative care
3.6
13.8
64
194
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
21.9
13.4
19
9
K56.7
ICD-10 Finland
Ileus, unspecified
9.4
13.4
27
30
JF2AB
NOMESCO Finland
Colongraphy with X-ray
29.2
13.0
17
6
Z93.3
ICD-10 Finland
Colostomy status
12.0
12.9
23
20
JGB01
NOMESCO Finland
Laparoscopic partial proctectomy and colorectal or coloanal anastomosis
51.4
12.9
15
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.4
12.9
65
211
WX704
NOMESCO Finland
Intubation
3.7
12.8
58
173
D18
ICPC
Change in faeces/bowel movements
8.2
12.8
28
36
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
7.4
12.5
29
41
A04AA01
ATC
ondansetron; systemic, rectal
3.6
11.9
55
167
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
19.5
11.7
17
9
C18.90
ICD-10 Finland
Malignant tumor in unspecified location in the colon without histology
19.5
11.7
17
9
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.8
11.6
49
138
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.7
11.5
50
144
A04AA55
ATC
palonosetron, combinations; systemic
8.2
11.5
25
32
369
Kela drug reimbursment
Regorafenib
35.9
11.3
14
*
B01AB04
ATC
dalteparin; parenteral
3.9
11.2
46
126
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
4.5
11.1
39
92
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
11.0
78
317
N02BE01
ATC
paracetamol; systemic, rectal
2.3
11.0
430
3642
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
11.0
133
712
JFB60
NOMESCO Finland
Resection of sigmoid colon with end colostomy
15.9
10.9
17
11
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
9.1
10.9
22
25
JN4CD
NOMESCO Finland
Very extensive body CT
4.2
10.7
40
101
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.3
10.6
39
97
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.0
10.5
23
30
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.2
10.4
39
99
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
6.1
10.3
27
46
JGB10
NOMESCO Finland
Partial proctectomy and end colostomy
40.9
10.0
12
*
SPAT1262
SPAT
Handing over of treatment supplies
2.2
9.9
119
631
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
56.1
9.7
11
*
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
56.1
9.7
11
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.2
9.5
35
87
L01BC59
ATC
trifluridine, combinations; systemic
30.7
9.4
12
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
9.4
57
208
JJB30
NOMESCO Finland
Excision of two segments of liver
+∞
9.4
9
*
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
3.7
9.2
40
116
ZX120
NOMESCO Finland
Intravenous
2.7
9.1
64
260
UJF30
NOMESCO Finland
Ileoscopy through colon
2.9
8.9
53
194
E0000UV
ATC
NA
1.8
8.8
188
1235
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
50.9
8.7
10
*
JJB10
NOMESCO Finland
Atypcal resection of liver
28.0
8.5
11
*
6434
FHL
Anterior resection
28.0
8.5
11
*
L01XE21
ATC
[U] regorafenib; oral
91.5
8.4
9
*
WX600
NOMESCO Finland
Single shot through catheter
8.8
8.4
17
20
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
11.0
8.3
15
14
WX725
NOMESCO Finland
Noninvasive ventilation
3.4
8.2
38
117
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.2
8.1
24
48
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
4.5
8.1
27
62
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.9
7.8
31
84
L01BC53
ATC
tegafur, combinations; systemic
25.4
7.6
10
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.9
7.5
44
160
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
7.5
66
303
JFF26
NOMESCO Finland
Sigmoidostomy
30.5
7.2
9
*
176
Kela drug reimbursment
Regorafenib
20.4
7.2
10
5
3018
Kela drug reimbursment
The combination of trifluridine and tipiracil
20.4
7.2
10
5
1506
Kela drug reimbursment
The combination of trifluridine and tipiracil
20.4
7.2
10
5
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
12.3
7.1
12
10
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
12.3
7.1
12
10
D16
ICPC
Rectal bleeding
5.3
7.0
20
39
A04AD12
ATC
aprepitant; systemic
5.8
6.8
18
32
JAH01
NOMESCO Finland
Laparoscopy
3.7
6.8
28
79
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.1
6.8
25
64
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
40.6
6.8
8
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.0
6.7
20
41
ZXC96
NOMESCO Finland
Robot assisted procedure
5.0
6.7
20
41
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.2
6.7
34
113
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
10.2
6.6
12
12
JFB00
NOMESCO Finland
Partial resection of small intestine
5.3
6.4
18
35
1540A
ICD-9 Finland
Malignant neoplasm of rectum, rectosigmoid junction and anus, Rectosigmoid junction[NEOPL MALIG JUNCT RECTOSIGM,INVASIIVINEN KARSINOOMA]
+∞
6.3
6
*
JFF24
NOMESCO Finland
Laparoscopic transversostomy
27.0
6.2
8
*
JFB43
NOMESCO Finland
Left hemicolectomy
7.8
6.2
13
17
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
5.0
6.1
18
37

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
386
541
22.41
306.31
10.2
4.2
24.2
34.2
ug/l
0.25
347
458
216
456
7.22
106.53
1.5
1.3
—
—
—
0
0
120
209
7.09
69.20
5.8
3.5
163.6
6784.3
u/ml
0.78
115
179
69
101
7.68
46.03
5.7
3.4
59.0
498.8
u/ml
1.05
61
94
390
2316
3.45
37.88
15.8
6.5
11.1
12.0
umol/l
1.10
379
2198
354
2017
3.18
36.26
10.5
4.8
33.4
34.8
g/l
4.25
343
1867
349
2002
3.09
34.75
6.1
4.3
—
—
—
0
0
124
437
3.38
28.33
2.5
2.2
0.2
0.2
g/l
0.82
118
405
113
399
3.32
25.55
1.4
1.4
—
—
—
0
0
359
2392
2.49
21.97
19.2
9.2
3.9
4.2
e9/l
2.19
325
2099
242
1393
2.33
20.18
5.3
4.3
—
—
—
0
0
311
1999
2.31
19.85
10.7
10.9
1.2
1.3
inr
0.96
95
545
244
1419
2.31
19.76
3.1
2.6
—
—
—
0
0
76
248
3.40
19.25
9.3
9.9
—
—
—
0
0
60
168
3.89
19.08
7.8
2.7
0.2
0.3
g/l
0.76
54
62
119
518
2.66
18.01
2.9
2.9
8.3
10.1
umol/l
0.38
109
464
233
1380
2.21
17.52
3.0
2.5
53.5
56.5
u/l
0.72
220
1280
144
737
2.30
15.09
6.2
3.3
0.8
0.8
mmol/l
2.04
136
686
135
680
2.31
14.64
2.0
2.4
2.3
2.3
g/l
0.14
130
627
426
3336
2.30
14.24
17.3
7.7
91.0
80.5
u/l
3.20
415
3104
129
654
2.28
13.68
1.9
2.5
18.9
22.2
%
2.17
109
551
48
145
3.54
13.61
9.3
6.9
1.3
1.3
mmol/l
0.05
43
128
116
573
2.30
13.03
8.7
7.1
0.5
1.3
mmol/l
1.45
94
449
358
2666
2.01
13.03
6.6
4.8
7.0
6.8
mmol/l
0.82
353
2509
315
2254
1.95
12.77
9.5
6.8
1.2
1.2
mmol/l
3.03
261
1895
181
1076
2.03
12.59
3.1
2.5
—
—
—
0
0
288
2082
1.82
10.49
8.5
5.8
1.2
1.2
mmol/l
1.83
271
1861
240
1646
1.82
10.37
2.8
2.2
—
—
—
0
0
164
1018
1.88
9.62
1.5
1.3
—
—
—
0
0
174
1109
1.84
9.35
5.1
3.9
89.8
85.6
%
1.49
174
1088
151
921
1.89
9.31
10.0
3.2
2.5
2.5
mmol/l
2.28
141
801
223
1537
1.77
9.18
8.4
3.5
2.3
2.3
mmol/l
0.04
207
1312
119
686
1.94
8.64
1.9
2.0
—
—
—
0
0
72
347
2.24
8.41
8.3
4.6
—
—
—
0
0
50
207
2.56
8.17
1.3
1.2
—
—
—
0
0
179
1200
1.73
7.87
2.2
2.1
3.6
3.2
mg/l
0.68
160
1013
49
212
2.44
7.31
2.2
2.0
2.3
3.0
ug/l
0.16
44
183
193
1366
1.64
6.72
5.4
4.0
7.4
7.4
ph
0.05
49
252
72
380
2.03
6.64
6.9
7.9
—
—
—
0
0
196
1404
1.62
6.45
4.7
5.4
—
—
—
0
0
461
4084
1.87
6.29
29.1
16.6
40.5
26.4
mg/l
6.13
433
3335
195
1406
1.60
6.19
3.8
3.3
—
—
—
0
0
348
2896
1.57
5.72
5.2
4.7
356.4
3863.1
e6/l
—
8
58
268
2112
1.53
5.60
5.2
5.7
0.2
0.2
e9/l
1.53
235
1850
248
1931
1.52
5.43
4.9
5.6
2.5
2.9
%
2.12
235
1799
248
1940
1.51
5.26
5.2
6.0
9.3
9.0
%
0.55
233
1812
27
103
2.71
5.23
3.6
4.4
2.2
2.4
mmol/l
0.09
21
67
247
1934
1.51
5.19
4.9
5.6
60.5
58.4
%
1.63
232
1807
250
1966
1.50
5.13
5.2
5.8
23.1
26.2
%
4.25
232
1822
241
1885
1.50
5.05
5.0
5.6
0.5
0.6
%
2.03
227
1760
95
599
1.71
4.99
4.4
5.6
1.1
1.0
mmol/l
0.73
90
548
258
2053
1.49
4.94
5.1
5.5
0.0
0.0
e9/l
0.96
223
1767
62
347
1.89
4.84
4.5
4.0
—
—
—
0
0
260
2080
1.48
4.80
5.1
5.6
1.6
1.9
e9/l
1.82
221
1816
45
229
2.05
4.60
2.4
2.5
—
—
—
0
0
254
2042
1.46
4.47
5.0
5.5
0.6
0.6
e9/l
0.37
216
1749
218
1704
1.47
4.43
2.8
2.7
128.5
157.0
ug/l
1.40
204
1545
87
557
1.67
4.30
1.4
1.3
—
—
—
0
0
250
2026
1.43
4.11
5.8
5.4
0.0
0.0
estimate
0.00
57
372
250
2027
1.43
4.09
4.3
4.0
0.0
0.0
estimate
0.00
57
377
153
1131
1.49
4.06
4.6
4.3
0.0
0.0
estimate
0.50
49
357
342
2942
1.44
4.01
5.5
4.5
—
—
—
0
0
69
424
1.72
3.97
3.0
3.1
285.0
232.2
ng/l
0.34
58
389
250
2056
1.40
3.65
4.4
4.0
0.0
0.0
estimate
0.00
55
360
19
74
2.62
3.58
3.3
2.7
57.7
59.7
%
0.22
19
74
18
70
2.63
3.41
3.0
2.3
4.1
4.8
e9/l
0.71
18
70
356
3941
0.72
3.23
4.6
4.8
1.4
1.4
mmol/l
0.71
323
3534
465
4321
1.54
3.08
35.3
19.8
4.0
4.0
mmol/l
0.64
454
4190
464
4310
1.54
3.08
35.3
19.7
139.1
139.6
mmol/l
4.64
454
4181
35
190
1.90
3.05
5.1
4.3
—
—
—
0
0
22
100
2.25
3.03
3.5
2.4
15.0
15.4
%
—
5
50
123
922
1.43
2.95
3.0
4.0
82.4
295.8
ng/l
2.43
97
782
12
41
2.97
2.87
1.0
1.3
—
—
nmol/l
—
0
0
77
530
1.53
2.83
1.7
1.7
—
—
—
0
0
5
168
0.29
2.74
1.0
1.3
—
—
—
0
0
66
444
1.55
2.69
3.4
3.6
2.0
1.9
mmol/l
0.10
52
353
21
99
2.17
2.68
1.1
1.2
—
54.0
—
0
5
66
446
1.55
2.64
3.4
3.6
5.5
5.8
kpa
1.43
66
432
376
4083
0.74
2.57
5.1
5.4
2.6
2.6
mmol/l
0.05
343
3670
340
3034
1.32
2.54
4.8
4.2
—
—
—
0
0
103
768
1.42
2.53
2.5
2.0
29.8
29.8
s
0.02
97
739
346
3099
1.32
2.50
3.7
4.2
16.3
13.6
mm/h
1.73
315
2813
139
1093
1.37
2.50
4.6
3.8
—
—
—
0
0
11
39
2.86
2.49
1.1
1.1
—
—
—
0
0
11
39
2.86
2.49
1.1
1.2
—
—
—
0
0
110
835
1.40
2.44
4.5
4.9
—
—
—
0
0
124
962
1.37
2.42
3.4
3.1
536.8
562.4
mosm/kgh2o
0.72
114
819
5
8
6.30
2.37
1.0
1.3
—
—
—
0
0
349
3810
0.76
2.31
4.2
4.3
1.3
1.3
mmol/l
0.26
318
3401
20
101
2.02
2.18
3.9
4.0
—
—
—
0
0
368
3975
0.77
2.12
4.6
4.8
4.5
4.4
mmol/l
0.33
337
3596
98
753
1.37
2.02
1.2
1.2
2.0
1.6
u/ml
0.18
19
196
469
4445
1.41
2.02
46.3
24.5
250.7
238.7
e9/l
2.72
455
4308
469
4445
1.41
2.02
46.1
24.4
91.1
91.7
fl
1.48
461
4355
469
4445
1.41
2.02
46.0
24.4
30.1
30.5
pg
3.37
461
4354
469
4446
1.41
2.00
46.2
24.5
4.3
4.4
e12/l
11.49
454
4292
469
4446
1.41
2.00
46.3
24.5
6.9
6.9
e9/l
0.29
454
4293
469
4447
1.41
1.99
46.5
24.6
127.0
134.2
g/l
18.47
460
4352
173
1450
1.28
1.94
4.4
3.5
91.8
122.5
e6/l
0.17
141
1144
126
1014
1.32
1.91
3.0
2.7
6.1
4.3
e6/l
0.80
117
888
5
12
4.19
1.82
1.6
1.8
—
—
—
0
0
15
73
2.08
1.82
2.0
2.9
—
—
—
0
0
37
240
1.58
1.81
1.4
1.8
1.9
1.5
g/l
1.44
32
209
150
1248
1.28
1.77
4.1
3.3
—
—
—
0
0
10
41
2.47
1.76
1.3
1.3
—
—
—
0
0
70
523
1.39
1.72
1.4
1.4
—
—
—
0
0
381
3535
1.26
1.70
32.0
18.0
37.4
39.0
%
1.95
215
2260
44
623
0.68
1.68
1.3
1.3
103.2
38.8
iu/ml
0.90
16
189
355
3270
1.25
1.68
40.9
20.5
14.8
13.9
%
13.84
350
3196
89
1118
0.76
1.63
1.6
1.7
1.4
1.3
mmol/l
0.37
73
928
22
128
1.75
1.63
1.1
1.2
—
—
—
0
0
5
14
3.59
1.62
1.0
1.0
—
—
—
0
0
454
4319
1.32
1.57
20.4
11.2
24.7
25.2
u/l
0.29
445
4135
77
595
1.34
1.55
2.2
2.5
2.0
1.8
%
0.27
71
531
125
1036
1.27
1.51
14.9
6.8
—
—
—
0
0
5
16
3.14
1.44
1.0
1.1
—
—
—
0
0
154
1317
1.24
1.41
4.4
3.3
0.4
0.5
e6/l
0.31
121
1009
54
401
1.39
1.40
1.4
2.1
186.1
140.7
ug/g
0.38
42
319
9
40
2.27
1.40
1.6
1.1
1.5
1.7
nmol/l
—
9
35
441
4198
1.27
1.39
30.8
15.9
—
—
—
0
0
164
1416
1.23
1.37
3.9
4.3
—
—
—
0
0
6
23
2.63
1.37
1.0
1.3
—
—
—
0
0
35
241
1.48
1.36
1.1
1.2
—
—
—
0
0
11
54
2.06
1.33
1.2
1.4
54.2
103.5
u/ml
—
5
11
187
1643
1.21
1.31
5.2
3.9
238.3
142.0
e6/l
0.45
145
1213
9
43
2.11
1.31
1.0
1.3
—
—
—
0
0
34
235
1.48
1.30
1.3
1.2
—
—
—
0
0
6
24
2.52
1.30
1.0
1.3
179.3
132.6
nmol/l
—
6
24
98
1181
0.79
1.29
2.9
2.8
5189.2
8497.1
umol/l
0.29
85
998
204
1814
1.20
1.25
18.4
10.1
0.0
0.0
e9/l
0.14
169
1483
12
63
1.93
1.23
1.2
1.4
—
—
—
0
0
210
1875
1.20
1.23
3.8
4.0
44.4
59.0
ng/l
0.34
173
1439
44
587
0.73
1.23
1.2
1.3
36.0
13.0
u/ml
0.61
14
219
7
142
0.49
1.22
1.4
1.6
—
—
—
0
0
57
439
1.33
1.20
2.1
2.7
78.4
69.6
e9/l
0.40
39
352
6
26
2.32
1.19
1.0
1.0
237.8
292.3
mg/l
—
6
21
16
95
1.71
1.15
3.9
2.4
—
—
—
0
0
102
1204
0.81
1.11
2.9
3.2
1.1
0.8
ug/l
0.53
77
824
5
21
2.39
1.09
1.4
1.4
—
—
—
0
0
368
3877
0.84
1.08
6.7
6.5
41.3
40.9
mmol/mol
0.36
334
3554
113
964
1.22
1.06
3.8
3.8
—
—
—
0
0
6
125
0.47
1.05
1.0
1.1
—
—
—
0
0
5
22
2.28
1.03
2.2
1.5
—
1734.8
—
0
5
5
22
2.28
1.03
1.6
1.9
—
—
—
0
0
118
1016
1.21
1.01
1.7
1.8
378.6
11786578.8
pmol/l
0.79
97
823
108
922
1.21
1.01
4.2
4.4
1.0
1.0
kg/l
0.44
16
146
40
304
1.34
0.95
3.6
3.4
124.2
127.6
g/l
0.41
40
299
0
32
0.00
0.95
0.0
1.3
—
—
—
0
0
107
1237
0.83
0.95
3.3
3.2
—
—
—
0
0
384
4013
0.85
0.93
4.8
5.0
6.2
6.1
mmol/l
0.73
346
3592
18
118
1.54
0.92
1.8
4.1
—
—
—
0
0
83
697
1.23
0.92
1.6
1.4
2.9
2.7
g/l
0.24
47
416
46
360
1.30
0.91
3.4
4.4
1.7
0.8
%
1.31
24
122
15
228
0.65
0.88
1.3
1.4
—
38.4
—
0
17
36
274
1.34
0.86
3.8
3.0
0.4
0.3
e6/l
0.23
36
268
48
381
1.29
0.86
3.5
2.8
4.5
4.3
kpa
0.44
48
366
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
8
48
1.68
0.79
1.0
1.3
—
—
—
0
0
21
148
1.44
0.79
4.4
5.7
—
—
—
0
0
5
96
0.52
0.78
1.4
1.2
3.5
3.8
mmol/l
—
5
88
5
96
0.52
0.78
1.2
1.1
—
—
—
0
0
0
26
0.00
0.78
0.0
2.2
—
7.4
—
0
18
0
26
0.00
0.78
0.0
3.8
—
37.4
—
0
7
0
26
0.00
0.78
0.0
1.2
—
—
—
0
0
47
379
1.26
0.76
1.2
1.4
—
—
—
0
0
11
67
1.66
0.75
1.8
2.0
30.1
33.3
pg
0.66
11
67
5
24
2.09
0.74
1.0
1.8
—
32.4
—
0
5
9
55
1.65
0.74
1.0
1.1
—
—
—
0
0
13
195
0.66
0.73
1.3
1.4
—
—
—
0
0
6
108
0.55
0.73
1.3
1.2
314.8
489.7
mg/l
—
6
100
13
84
1.56
0.72
1.8
1.8
—
—
—
0
0
13
85
1.54
0.69
4.3
2.9
—
—
—
0
0
5
28
1.79
0.66
1.0
1.3
1.6
1.3
promille
—
5
21
5
28
1.79
0.66
1.0
2.0
—
—
—
0
0
17
120
1.43
0.65
3.8
2.4
7.9
7.7
kpa
0.24
17
104
6
105
0.57
0.62
1.2
1.6
—
—
—
0
0
55
466
1.20
0.59
5.1
4.1
—
—
—
0
0
11
162
0.67
0.59
1.1
1.1
—
30.2
titre
—
0
6
24
309
0.77
0.59
1.2
1.5
—
—
—
0
0
131
1193
1.13
0.57
1.7
1.6
17.8
20.3
nmol/l
1.41
118
998
12
171
0.69
0.55
1.6
2.0
—
—
—
0
0
161
1487
1.12
0.55
4.3
4.0
15.7
10.1
mg/mmol
0.76
109
954
28
223
1.27
0.53
1.1
1.3
—
—
—
0
0
6
99
0.60
0.52
1.8
2.3
—
—
—
0
0
9
65
1.39
0.51
1.1
1.1
—
—
—
0
0
13
179
0.72
0.50
2.4
2.2
485.6
698.3
ug/l
0.25
13
169
7
47
1.50
0.47
1.7
2.6
—
—
—
0
0
40
339
1.19
0.45
3.4
4.5
0.4
0.1
%
0.77
19
113
38
322
1.19
0.44
2.6
4.3
0.6
0.5
%
0.25
13
90
153
1428
1.10
0.43
3.4
3.1
7.0
7.5
mmol/l
0.76
130
1173
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
36.2
—
0
8
0
17
0.00
0.40
0.0
5.5
—
—
—
0
0
0
17
0.00
0.40
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
3.1
—
—
—
0
0
7
101
0.69
0.40
2.1
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
3.4
—
30.2
—
0
14
42
482
0.86
0.38
1.2
1.3
897.1
437.9
titre
—
7
116
134
1428
0.92
0.35
1.9
2.1
184.8
266.9
u/l
0.46
123
1325
63
568
1.12
0.34
1.1
1.2
—
—
—
0
0
10
133
0.75
0.34
10.7
11.0
—
—
—
0
0
16
199
0.80
0.34
1.1
1.3
—
—
—
0
0
11
143
0.76
0.32
6.1
3.8
—
—
—
0
0
11
83
1.33
0.32
1.2
1.2
—
—
—
0
0
203
1946
1.07
0.30
2.2
2.1
83.7
93.7
pmol/l
3.14
139
1026
10
76
1.32
0.28
1.2
1.6
61.4
58.3
%
—
10
76
5
75
0.66
0.26
1.0
1.1
—
—
—
0
0
11
136
0.80
0.23
1.4
1.2
—
—
—
0
0
5
38
1.32
0.23
1.4
1.4
—
—
—
0
0
40
362
1.11
0.23
1.2
1.5
—
—
—
0
0
23
200
1.16
0.22
1.2
1.2
99.0
124.4
iu/ml
—
7
75
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
1799.2
—
0
10
0
12
0.00
0.21
0.0
1.3
—
141.8
—
0
12
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
6.4
—
0.7
—
0
12
0
14
0.00
0.20
0.0
1.1
—
3.3
—
0
14
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
49
453
1.09
0.19
2.1
2.6
9.4
7.0
ug/l
0.22
39
397
6
52
1.16
0.19
1.2
1.3
—
—
—
0
0
102
972
1.06
0.19
1.9
1.8
1311.9
1201.4
nmol/l
0.44
85
726
22
248
0.88
0.18
6.2
4.5
—
—
—
0
0
7
60
1.17
0.18
1.1
1.3
—
—
—
0
0
35
320
1.10
0.17
3.5
4.5
0.0
0.1
%
0.78
12
96
27
299
0.90
0.17
3.0
2.9
—
—
—
0
0
73
690
1.07
0.17
24.1
26.6
1.5
1.4
inr
0.36
20
92
7
63
1.11
0.17
1.4
1.4
—
—
—
0
0
38
412
0.92
0.17
3.8
3.0
64.5
66.2
g/l
0.52
33
371
12
141
0.85
0.16
1.5
1.4
—
—
—
0
0
6
78
0.77
0.15
1.5
1.5
30.1
31.4
g/l
—
6
68
27
245
1.11
0.15
2.0
3.7
—
—
—
0
0
145
1405
1.04
0.15
3.5
3.2
73.7
259.2
mg/l
1.36
103
921
11
93
1.19
0.14
1.0
1.2
—
—
—
0
0
21
233
0.90
0.14
3.0
2.9
—
—
—
0
0
163
1586
1.04
0.14
2.5
3.1
1255.1
1611.4
ng/l
0.99
142
1380
9
107
0.84
0.13
2.4
1.9
38.7
44.5
nmol/l
—
9
100
9
109
0.82
0.13
1.7
1.7
—
—
—
0
0
94
907
1.04
0.12
1.8
1.6
1.9
1.4
mg/l
0.63
77
716
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
6
73
0.82
0.07
3.0
2.6
—
—
—
0
0
8
74
1.08
0.07
2.5
3.3
—
—
—
0
0
38
363
1.05
0.07
1.5
1.5
—
—
—
0
0
24
255
0.94
0.07
2.3
2.9
4.5
4.1
e9/l
0.26
19
181
37
385
0.96
0.06
3.2
3.5
—
—
—
0
0
13
141
0.92
0.05
2.8
2.6
319.7
94.9
ug/min
—
8
86
12
130
0.92
0.04
1.0
1.0
—
—
—
0
0
14
130
1.08
0.04
1.5
1.6
—
—
—
0
0
10
109
0.92
0.04
1.0
1.1
—
—
—
0
0
296
2974
0.99
0.02
3.8
3.6
14.9
15.0
pmol/l
0.11
272
2622
371
3697
1.01
0.02
4.4
4.5
2.1
2.0
mu/l
1.21
340
3275
43
438
0.98
0.01
1.3
1.6
—
—
—
0
0
10
97
1.03
0.00
1.3
2.6
—
—
—
0
0
34
345
0.98
0.00
3.6
2.6
—
—
—
0
0
12
119
1.01
0.00
1.2
1.2
—
2.5
—
0
11
35
351
1.00
0.00
1.4
1.4
—
—
—
0
0
209
2089
1.00
0.00
4.9
5.4
3.7
3.7
ug/l
0.01
184
1839
0
9
0.00
0.00
0.0
8.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
16.4
—
0
6
5
54
0.93
0.00
2.0
2.9
—
—
—
0
0
7
77
0.91
0.00
1.0
1.6
—
—
—
0
0
8
80
1.00
0.00
1.3
1.4
—
—
—
0
0
5
52
0.96
0.00
2.2
1.5
—
—
—
0
0
6
66
0.91
0.00
3.2
1.7
351.3
266.3
mu/l
—
6
60
5
52
0.96
0.00
2.2
1.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
5
51
0.98
0.00
1.4
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
5
52
0.96
0.00
2.2
1.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
5.4
—
—
—
0
0
5
52
0.96
0.00
2.2
1.5
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
2.3
—
7.7
—
0
6
7
79
0.88
0.00
1.1
1.2
52.0
49.1
u/l
—
7
66
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
39.1
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
6
59
1.02
0.00
1.2
1.8
2.7
0.9
g/l
—
6
46
0
5
0.00
0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
7.2
—
0
6
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_RECTOSIGMOID_JUNCTION – Malignant neoplasm of rectosigmoid junction

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).