This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_RECTOSIGMOID_JUNCTION_EXALLC for full statistics.
Malignant neoplasm of rectosigmoid junction
C3_RECTOSIGMOID_JUNCTION
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
541 |
4. Check minimum number of eventsNone |
541 |
5. Include endpointsNone |
541 |
6. Filter based on genotype QC (FinnGen only) |
541 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of rectosigmoid junction
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of rectosigmoid junction, excluding all cancers (controls excluding all cancers)
- Colorectal cancer
- Colorectal cancer, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of digestive organs
- Malignant neoplasm of digestive organs, excluding all cancers (controls excluding all cancers)
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 541 | 197 | 344 |
| Unadjusted period prevalence (%) | 0.12 | 0.07 | 0.15 |
| Median age at first event (years) | 68.87 | 66.30 | 70.34 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 497
- Matched controls
- 4968
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
+∞
323.0
423
*
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
565.6
240.9
221
7
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
73.9
193.0
216
51
L01BC06
ATC
capecitabine; oral
50.4
173.5
210
71
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
86.7
164.1
179
32
130
Kela drug reimbursment
Malignant tumour
19.4
159.3
274
296
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
94.2
136.0
147
22
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
15.2
116.2
213
234
UJF32
NOMESCO Finland
Coloscopy
9.2
111.1
338
933
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
48.9
89.4
108
28
A03FA01
ATC
metoclopramide; systemic, rectal
7.3
82.4
255
630
A04AA02
ATC
granisetron; systemic, transdermal
14.0
77.4
141
137
WX302
NOMESCO Finland
Thoracal epidural anesthesy
13.4
74.5
138
138
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
126.5
62.5
66
6
H02AB02
ATC
dexamethasone; systemic
7.4
56.6
152
280
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
12.9
53.0
98
93
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
19.2
51.6
80
49
JN4BD
NOMESCO Finland
Extensive body CT
6.3
51.0
156
338
B01AB05
ATC
enoxaparin; parenteral
4.3
49.8
273
1101
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
29.1
42.2
57
22
JG1BG
NOMESCO Finland
MRI of rectum
73.9
41.8
47
7
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
12.1
39.9
75
72
JGB04
NOMESCO Finland
Laparoscopic partial proctectomy with partial excision of mesorectum
418.8
39.6
39
*
TPH07
NOMESCO Finland
Cathetrisation of artery
5.4
39.2
134
320
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
7.4
38.8
99
162
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
17.2
38.1
61
40
C18.79
ICD-10 Finland
Malignant tumor of the sigmoid or other unspecified histology
44.8
36.9
45
11
C18.7
ICD-10 Finland
Malignant neoplasm: Sigmoid colon
65.3
36.8
42
7
JGB03
NOMESCO Finland
Partial proctectomy with partial excision of mesorectum
105.6
36.3
39
*
WF001
NOMESCO Finland
Preoperative radiotherapy
29.3
35.7
48
18
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
8.5
35.1
80
109
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
42.6
34.9
43
11
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
61.9
34.7
40
7
C20
ICD-10 Finland
Malignant neoplasm of rectum
44.6
33.6
41
10
C20.99
ICD-10 Finland
Malignant tumor of the rectum other or unspecified histology
51.2
32.0
38
8
JFF23
NOMESCO Finland
Transversostomy
24.6
32.0
45
20
JN4AD
NOMESCO Finland
Body CT examination
5.6
30.9
98
210
JGB07
NOMESCO Finland
Laparoscopic partial proctectomy with total excision of mesorectum
110.0
29.0
31
*
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
14.3
27.5
47
36
D75
ICPC
Malignant neoplasm colon/rectum
24.1
26.9
38
17
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.5
26.2
64
96
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
53.0
25.5
30
6
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
12.6
25.5
46
40
UJG02
NOMESCO Finland
Proctoscopy
11.4
25.4
48
46
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
13.7
25.4
44
35
8480/3-C19.9
ICD-O-3
Mucinous adenocarcinoma of rectosigmoid junction
+∞
25.2
24
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
24.6
189
852
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
22.0
24.2
35
17
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
9.2
24.0
51
61
JFB54
NOMESCO Finland
Laparoscopic resection of sigmoid colon with partial proctectomy
91.3
23.9
26
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.8
23.7
211
1040
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
38.4
23.2
29
8
WZC30
NOMESCO Finland
Teaching
3.6
23.1
116
383
JFB46
NOMESCO Finland
Resection of sigmoid colon
18.7
23.0
35
20
JG1CG
NOMESCO Finland
Extensive MRI of rectum
42.3
22.9
28
7
JFB53
NOMESCO Finland
Resection of sigmoid colon with partial proctectomy
+∞
21.0
20
*
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
18.3
20.3
31
18
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
60.1
20.1
23
*
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
207.9
19.7
20
*
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
11.7
19.5
36
33
B01AB10
ATC
tinzaparin; parenteral
4.4
19.4
74
189
ZXE20
NOMESCO Finland
More than three and less than five hours
3.1
19.2
118
447
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
5.1
19.2
63
138
TJF80
NOMESCO Finland
Ostomy education
16.7
19.0
30
19
TPX10
NOMESCO Finland
Implantation of vascular injection port
8.4
19.0
42
54
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
6.4
18.1
48
81
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
7.9
17.8
41
56
WX402
NOMESCO Finland
General anaesthesia
2.9
16.1
108
428
SPAT1125
SPAT
Stoma care and guidance
10.9
15.9
30
29
XX3DW
NOMESCO Finland
Time consuming IT work
3.3
15.9
87
300
Z93
ICD-10 Finland
Artificial opening status
27.3
15.7
21
8
N02AA05
ATC
oxycodone; systemic
2.7
15.4
124
550
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
29.7
15.3
20
7
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.7
15.2
44
83
JGB06
NOMESCO Finland
Partial proctectomy with total excision of mesorectum
24.3
15.2
21
9
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
58.5
14.9
17
*
JAH00
NOMESCO Finland
Laparotomy
6.2
14.5
39
67
JFF10
NOMESCO Finland
Loop enterostomy
16.4
14.0
22
14
Z51.5
ICD-10 Finland
Palliative care
3.6
13.8
64
194
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
21.9
13.4
19
9
K56.7
ICD-10 Finland
Ileus, unspecified
9.4
13.4
27
30
JF2AB
NOMESCO Finland
Colongraphy with X-ray
29.2
13.0
17
6
Z93.3
ICD-10 Finland
Colostomy status
12.0
12.9
23
20
JGB01
NOMESCO Finland
Laparoscopic partial proctectomy and colorectal or coloanal anastomosis
51.4
12.9
15
*
JN3AD
NOMESCO Finland
Abdominal CT examination
3.4
12.9
65
211
WX704
NOMESCO Finland
Intubation
3.7
12.8
58
173
D18
ICPC
Change in faeces/bowel movements
8.2
12.8
28
36
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
7.4
12.5
29
41
A04AA01
ATC
ondansetron; systemic, rectal
3.6
11.9
55
167
C18.90
ICD-10 Finland
Malignant tumor in unspecified location in the colon without histology
19.5
11.7
17
9
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
19.5
11.7
17
9
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.8
11.6
49
138
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.7
11.5
50
144
A04AA55
ATC
palonosetron, combinations; systemic
8.2
11.5
25
32
369
Kela drug reimbursment
Regorafenib
35.9
11.3
14
*
B01AB04
ATC
dalteparin; parenteral
3.9
11.2
46
126
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
4.5
11.1
39
92
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.7
11.0
78
317
N02BE01
ATC
paracetamol; systemic, rectal
2.3
11.0
430
3642
TPH04
NOMESCO Finland
Cathetrisation of vein
2.2
11.0
133
712
JFB60
NOMESCO Finland
Resection of sigmoid colon with end colostomy
15.9
10.9
17
11
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
9.1
10.9
22
25
JN4CD
NOMESCO Finland
Very extensive body CT
4.2
10.7
40
101
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.6
10.6
48
143
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
4.3
10.6
39
97
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.0
10.5
23
30
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.2
10.4
39
99
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
6.1
10.3
27
46
JGB10
NOMESCO Finland
Partial proctectomy and end colostomy
40.9
10.0
12
*
SPAT1262
SPAT
Handing over of treatment supplies
2.2
9.9
119
631
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
56.1
9.7
11
*
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
56.1
9.7
11
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.2
9.5
35
87
L01BC59
ATC
trifluridine, combinations; systemic
30.7
9.4
12
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
9.4
57
208
JJB30
NOMESCO Finland
Excision of two segments of liver
+∞
9.4
9
*
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
3.7
9.2
40
116
ZX120
NOMESCO Finland
Intravenous
2.7
9.1
64
260
UJF30
NOMESCO Finland
Ileoscopy through colon
2.9
8.9
53
194
E0000UV
ATC
NA
1.8
8.8
188
1235
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
50.9
8.7
10
*
6434
FHL
Anterior resection
28.0
8.5
11
*
JJB10
NOMESCO Finland
Atypcal resection of liver
28.0
8.5
11
*
L01XE21
ATC
[U] regorafenib; oral
91.5
8.4
9
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
8.4
194
1307
WX600
NOMESCO Finland
Single shot through catheter
8.8
8.4
17
20
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
11.0
8.3
15
14
WX725
NOMESCO Finland
Noninvasive ventilation
3.4
8.2
38
117
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.2
8.1
24
48
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
4.5
8.1
27
62
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.9
7.8
31
84
L01BC53
ATC
tegafur, combinations; systemic
25.4
7.6
10
*
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.9
7.5
44
160
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.4
7.5
66
303
JFF26
NOMESCO Finland
Sigmoidostomy
30.5
7.2
9
*
1506
Kela drug reimbursment
The combination of trifluridine and tipiracil
20.4
7.2
10
5
176
Kela drug reimbursment
Regorafenib
20.4
7.2
10
5
3018
Kela drug reimbursment
The combination of trifluridine and tipiracil
20.4
7.2
10
5
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
12.3
7.1
12
10
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
12.3
7.1
12
10
D16
ICPC
Rectal bleeding
5.3
7.0
20
39
A04AD12
ATC
aprepitant; systemic
5.8
6.8
18
32
JAH01
NOMESCO Finland
Laparoscopy
3.7
6.8
28
79
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
4.1
6.8
25
64
XJA00
NOMESCO Finland
Intraoperative abdominal ultrasonography
40.6
6.8
8
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.0
6.7
20
41
ZXC96
NOMESCO Finland
Robot assisted procedure
5.0
6.7
20
41
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.2
6.7
34
113
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
10.2
6.6
12
12
JFB00
NOMESCO Finland
Partial resection of small intestine
5.3
6.4
18
35
1540A
ICD-9 Finland
Malignant neoplasm of rectum, rectosigmoid junction and anus, Rectosigmoid junction[NEOPL MALIG JUNCT RECTOSIGM,INVASIIVINEN KARSINOOMA]
+∞
6.3
6
*
JFF24
NOMESCO Finland
Laparoscopic transversostomy
27.0
6.2
8
*
JFB43
NOMESCO Finland
Left hemicolectomy
7.8
6.2
13
17
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
5.0
6.1
18
37
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_RECTOSIGMOID_JUNCTION – Malignant neoplasm of rectosigmoid junction
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).