Transient acantholytic dermatosis [Grover]

L12_GROVER

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — L11.1 Cause of death: ICD-10 — L11.1 2 out of 7 registries used, show all original rules.	67
4. Check minimum number of events None	67
5. Include endpoints None	67
6. Filter based on genotype QC (FinnGen only)	66

Control definitions (FinnGen only)

Control exclude: L12_BULLOUS

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: L11
Name in latin: Dermatosis acantholytica transitoria

NAME	L12_GROVER
CONTROL_EXCLUDE	L12_BULLOUS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L111
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L111
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Transient acantholytic dermatosis [Grover] based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	277	60	216
Only index persons	264	57	207
Unadjusted period prevalence (%)
Whole population	0.01	0.00	0.01
Only index persons	0.01	0.00	0.01
Median age at first event (years)
Whole population	74.29	72.41	74.76
Only index persons	74.06	72.09	74.61

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	66	18	48
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	74.41	75.94	73.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
67: Matched controls
670

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

L11.1

ICD-10 Finland

Transient acantholytic dermatosis [Grover]

+∞

96.2

L30.9

ICD-10 Finland

Dermatitis, unspecified

15.2

29.5

TQX10

NOMESCO Finland

Biopsy of skin and subcutaneous tissue

15.7

28.4

E0000UV, ,

ATC

14.1

21.5

164

D07BB04

ATC

hydrocortisone butyrate and antiseptics; topical

9.0

16.2

D07AC01

ATC

betamethasone; topical

7.9

15.5

153

D05BB02

ATC

acitretin; oral

32.4

14.8

D07AC13

ATC

mometasone; topical

6.0

12.2

109

D07AB02

ATC

hydrocortisone butyrate; topical

5.8

11.7

118

D07AD01

ATC

clobetasol; topical

5.1

7.6

WXQ27

NOMESCO Finland

UVB narrow spectrum light therapy

+∞

7.4

XQ845

NOMESCO Finland

Dermatoscopy

23.1

7.4

XQ848

NOMESCO Finland

Dermatological photography

19.2

7.0

D10BA01

ATC

isotretinoin; oral

14.3

6.9

D07AB08

ATC

desonide; topical

6.4

6.8

L29.8

ICD-10 Finland

Other pruritus

76.9

6.5

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40768443) Skin Pathology biopsy report

25.69

17.87

1.8

1.0

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

244

2.93

4.34

2.5

2.1

94.13

89.39

pmol/l

0.28

129

(40768797) Stomach Pathology biopsy report

3.06

3.96

1.5

1.3

—

(3022145) Colonoscopy Study observation

3.33

3.94

1.7

1.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

3.67

3.91

1.2

2.2

—

(3007164) IgA [Mass/volume] in Serum or Plasma

3.05

3.83

1.8

1.4

2.37

2.54

g/l

0.14

(40760892) CBC W Ordered Manual Differential panel - Blood

246

2.72

3.82

8.0

5.8

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

6.82

3.62

1.1

1.6

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

139

2.58

3.33

2.2

1.6

1.18

1.24

mmol/l

0.19

117

(3020630) Protein [Mass/volume] in Serum or Plasma

3.16

3.32

1.3

2.2

66.64

65.16

g/l

0.41

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

5.89

3.30

1.3

—

(40768804) Tissue Pathology biopsy report

215

2.46

3.22

3.2

2.3

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

207

2.45

3.19

2.4

2.5

94.95

73.73

nmol/l

2.99

175

(3038026) Centromere Ab [Units/volume] in Serum

8.87

2.79

1.0

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

6.46

2.76

1.3

1.4

—

(3022217) INR in Platelet poor plasma by Coagulation assay

311

2.36

2.73

18.7

18.2

1.43

1.39

inr

0.08

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

304

2.30

2.63

3.8

6.3

10.77

13.19

umol/l

1.23

292

(40760888) Immunoglobulin light chains.free panel - Serum

5.87

2.60

1.2

4.8

—

(3004616) Nuclear Ab [Presence] in Serum

7.60

2.59

1.2

1.0

—

(3002256) Pathology report gross observation

2.64

2.46

1.5

1.3

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

5.37

2.46

1.2

1.3

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

6.64

2.41

1.0

1.5

0.22

0.27

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

5.90

2.25

1.0

1.6

1.18

1.19

g/l

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

288

2.09

2.20

4.5

8.2

1.23

1.19

mmol/l

3.17

245

(3005719) IgG [Mass/volume] in Serum or Plasma

2.99

2.18

1.6

2.4

8.94

10.23

g/l

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.78

2.12

1.4

1.5

—

(3008898) HLA-B27 [Presence]

5.30

2.11

1.0

1.2

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

535

3.13

2.06

19.1

18.0

24.51

27.61

mg/l

0.38

450

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

3.22

2.01

1.3

2.8

11.53

9.92

g/l

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

3.22

2.01

1.3

2.8

2.90

2.92

g/l

—

(3049717) Cytology report of Urine Cyto stain

3.10

1.93

3.6

3.2

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

514

2.60

1.87

6.4

7.0

39.88

41.96

mmol/mol

1.18

471

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.99

1.86

1.3

2.7

3.65

3.35

g/l

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.99

1.86

1.3

2.7

7.34

7.06

g/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

2.99

1.86

1.3

2.7

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

181

1.94

1.80

3.1

3.2

0.64

0.76

ug/l

0.58

125

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.36

1.70

1.7

2.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

376

1.98

1.69

5.3

4.7

—

(36660697) Celiac disease serology panel - Serum

2.70

1.66

1.3

1.2

—

(3018418) pH of Serum or Plasma

169

1.88

1.62

3.2

4.5

7.40

7.39

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

524

2.39

1.57

5.5

5.4

6.18

6.24

mmol/l

0.11

463

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

3.09

1.38

1.4

1.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

250

1.73

1.37

3.9

4.7

21.22

21.97

0.14

130

(3019225) pH of Specimen

2.20

1.36

2.5

5.7

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

515

2.22

1.36

4.8

4.9

1.52

1.39

mmol/l

1.19

452

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

519

2.14

1.36

6.2

4.9

4.32

4.35

mmol/l

0.09

465

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

507

2.07

1.31

21.5

17.3

74.10

73.35

ml/min/173m2

0.10

420

(3019309) Folate [Moles/volume] in Red Blood Cells

136

1.79

1.29

1.8

1117.31

1199.74

nmol/l

0.11

103

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

255

1.68

1.24

2.3

2.8

—

(40761536) Microorganisms panel - Urine sediment

2.18

1.24

4.6

4.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.13

1.18

1.2

1.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

2.40

1.14

1.0

1.4

—

(3028026) IgM [Mass/volume] in Serum or Plasma

2.32

1.12

1.3

1.6

3.53

0.93

g/l

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.11

1.03

1.7

1.8

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

102

1.75

1.02

1.6

6.6

0.93

1.05

mmol/l

0.92

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

217

1.59

1.02

3.9

3.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

534

1.88

0.97

5.8

5.6

2.37

2.54

mmol/l

0.84

474

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

221

1.55

0.93

2.0

3.5

1048.35

1679.49

ng/l

0.78

182

(40761511) CBC panel - Blood by Automated count

546

1.95

0.89

18.6

18.1

—

(3013512) EKG study

195

1.54

0.88

3.5

4.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

261

1.52

0.88

2.2

2.6

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

499

1.74

0.87

5.4

4.4

1.07

1.29

mmol/l

2.57

433

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

331

1.52

0.86

6.1

5.3

2.04

2.08

ug/l

0.06

286

(3000494) Fungus identified in Specimen by Culture

1.77

0.81

1.3

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.00

0.72

1.0

1.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

105

1.55

0.67

1.7

1.9

—

(3003694) ABO and Rh group [Type] in Blood

123

1.51

0.66

1.3

—

(36304419) Bacteria [Presence] in Urine

161

1.44

0.62

4.6

3.2

—

(4035726) Immunohistochemistry procedure

1.58

0.61

1.3

1.4

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

190

1.41

0.60

2.3

2.2

162.96

222.13

u/l

0.38

178

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.78

0.59

1.5

1.4

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.63

0.59

2.1

2.4

5.50

13.02

umol/l

—

(40758558) Short blood count panel - Blood

136

1.44

0.57

8.1

6.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.51

0.55

3.6

3.2

0.76

1.53

e6/l

—

(3044889) 12 lead EKG panel

381

1.36

0.52

4.3

4.5

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

139

1.40

0.51

3.6

2.3

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.48

0.50

3.4

3.0

0.25

0.93

e6/l

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

1.55

0.49

3.0

2.0

69.57

219.10

ng/l

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.55

0.49

1.7

5.0

95.71

90.60

ng/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.51

0.49

5.9

3.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.41

0.0

1.6

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.00

0.41

0.0

1.4

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.3

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.41

0.0

1.3

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.47

0.37

1.0

1.6

1.75

1.97

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.40

0.35

1.3

1.4

—

(3026008) Bacteria identified in Urine by Culture

178

1.26

0.31

4.9

3.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

128

0.74

0.30

2.0

3.7

—

(1761868) Lipid panel - Serum or Plasma

160

1.26

0.30

2.7

3.7

—

(3023368) Bacteria identified in Blood by Culture

190

1.24

0.28

4.8

4.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.31

0.27

2.0

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.25

0.26

2.0

1.8

—

(3044640) Blood type and Crossmatch panel - Blood

194

1.20

0.22

2.1

2.4

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.21

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.2

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.0

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.21

0.0

1.6

—

224.75

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.3

—

(3012516) Albumin [Mass/volume] in Urine

195

1.19

0.21

2.6

3.2

4488.41

74.80

mg/l

—

133

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

110

1.23

0.19

1.7

2.5

2.13

2.19

g/l

0.12

(3003338) MCHC [Mass/volume]

403

0.87

0.17

27.6

23.4

330.05

331.71

g/l

0.52

403

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.76

0.16

5.5

10.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

162

1.15

0.13

3.4

4.0

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

229

0.88

0.13

3.2

4.3

—

(3022948) Iron [Moles/volume] in Serum or Plasma

124

1.16

0.12

1.8

2.5

12.86

11.05

umol/l

0.41

111

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

273

1.11

0.10

3.3

4.4

21.43

56.91

ng/l

1.99

221

(3035350) Ketones [Presence] in Urine by Test strip

284

1.10

0.09

3.0

4.1

0.00

estimate

-0.00

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.04

0.09

1.6

1.4

—

(40761535) Cells panel - Urine sediment

1.14

0.09

1.2

3.0

—

(3009508) Creatinine [Moles/volume] in Urine

196

1.10

0.08

2.7

3.1

5.84

7.67

mmol/l

1.29

155

(3007853) Bacteria identified in Skin by Aerobe culture

1.03

0.08

3.1

1.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

207

1.09

0.07

3.4

3.8

38.37

10.79

mg/mmol

—

134

(3018677) aPTT in Platelet poor plasma by Coagulation assay

109

0.90

0.04

1.5

1.8

33.30

29.31

—

104

(3029937) Albumin [Presence] in Urine by Test strip

171

1.07

0.03

3.2

4.0

0.00

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

282

1.05

0.02

4.0

5.5

0.00

estimate

—

(3015736) pH of Urine

217

1.02

0.00

2.2

3.9

—

6.00

—

(3009261) Glucose [Presence] in Urine by Test strip

287

1.02

0.00

3.0

4.1

0.00

estimate

-0.00

(46235355) HIV 1 and 2 tests - Meaningful Use set

0.85

0.00

1.6

1.5

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

4.0

—

3.56

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

5.4

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

1.7

—

9.55

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(40762485) Glomerular basement membrane Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture

0.00

-0.00

0.0

2.0

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3018387) Mycoplasma pneumoniae IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

0.97

-0.00

2.9

6.8

102.56

103.46

mmol/l

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

-0.00

0.0

2.7

—

(3023323) Follitropin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

24.80

—

(3011544) Albumin [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.0

—

17.32

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.3

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

-0.00

0.0

5.0

—

58.20

—

(3016724) Homocysteine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

16.18

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

3.2

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

3.6

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

5.4

—

308.14

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

-0.00

0.0

1.0

—

125.40

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3052649) Adenosine deaminase [Enzymatic activity/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

12.14

—

(3042936) Bacteria identified in Isolate by Culture

1.01

-0.00

2.7

1.8

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

2.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.7

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.6

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

5.4

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.7

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3051593) INR in Capillary blood by Coagulation assay

0.00

-0.00

0.0

13.8

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint L12_GROVER and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have L12_GROVER.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: L12_GROVER – Transient acantholytic dermatosis [Grover]

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Transient acantholytic dermatosis [Grover]

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints