No definition available.
Benign neoplasm: Ill-defined sites within the digestive system
CD2_BENIGN_DIGESTIVE_NOS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
215 |
4. Check minimum number of eventsNone |
215 |
5. Include endpointsNone |
215 |
6. Filter based on genotype QC (FinnGen only) |
213 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D13
- Name in latin
- Neoplasma benignum systematis digestorii loco male specificato
Similar endpoints
↥List of similar endpoints to
Benign neoplasm: Ill-defined sites within the digestive system
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of other and ill-defined parts of digestive system
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1435 | 836 | 586 |
| Only index persons | 1139 | 692 | 447 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.02 |
| Only index persons | 0.02 | 0.03 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 61.79 | 60.50 | 63.56 |
| Only index persons | 60.47 | 58.95 | 62.82 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 213 | 137 | 76 |
| Unadjusted period prevalence (%) | 0.04 | 0.05 | 0.03 |
| Median age at first event (years) | 61.40 | 59.51 | 64.79 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 215
- Matched controls
- 2150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.9
ICD-10 Finland
Benign neoplasm: Ill-defined sites within the digestive system
+∞
238.2
182
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
7.6
22.0
34
52
21199
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Unspecified site
+∞
21.2
20
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
15.0
18.1
30
23
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.1
14.6
46
133
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.1
14.2
97
456
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
10.7
13.1
25
26
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
34.4
12.8
16
5
UJF32
NOMESCO Finland
Coloscopy
2.9
11.9
81
374
TPH07
NOMESCO Finland
Cathetrisation of artery
3.6
11.8
44
142
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
63.2
10.7
12
*
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
15.3
10.7
17
12
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
13.0
10.6
18
15
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.5
10.1
99
541
JN3AD
NOMESCO Finland
Abdominal CT examination
3.3
9.9
42
147
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.8
9.5
31
91
2119X
ICD-9 Finland
Benign neoplasm of other parts of digestive system, Other and unspecified site[NEOPLASMA BENIGNUM ALIUD ORG DIGEST AL DEF SEU NUD]
+∞
9.4
9
*
B01AB04
ATC
dalteparin; parenteral
4.8
9.3
22
50
N02AX02
ATC
tramadol; systemic, rectal
2.4
9.3
116
701
WX402
NOMESCO Finland
General anaesthesia
2.7
9.0
60
269
A02BC02
ATC
pantoprazole; systemic
2.8
9.0
170
1233
WX408
NOMESCO Finland
General anesthesy, balanced
2.5
8.7
74
373
ZXE00
NOMESCO Finland
One hour or less
2.4
8.7
102
595
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
8.1
65
318
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
8.3
8.0
17
22
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.9
8.0
18
39
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.8
7.7
24
68
JAH00
NOMESCO Finland
Laparotomy
6.2
7.4
19
33
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.3
7.3
30
102
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
31.2
7.2
9
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.1
7.2
20
52
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.4
6.9
54
259
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
11.5
6.9
12
11
JLC30
NOMESCO Finland
Pancreatoduodenectomy
18.7
6.3
9
5
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
+∞
6.3
6
*
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
27.6
6.3
8
*
A10AE04
ATC
insulin glargine; parenteral
2.9
6.2
31
118
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
62
205
3.84
16.40
3.7
3.4
6.42
7.53
umol/l
0.21
56
183
30
63
5.37
14.02
1.3
1.4
289.57
284.56
ug/g
0.04
21
32
37
94
4.55
13.83
2.5
3.1
562.44
1644.89
u/ml
0.30
29
78
59
217
3.37
13.01
4.4
4.3
13.93
9.26
ug/l
0.33
47
187
46
154
3.53
11.66
2.9
2.4
0.21
0.21
g/l
0.21
46
144
48
168
3.39
11.34
3.1
2.5
34.69
28.85
u/l
0.71
48
140
131
799
2.64
10.77
6.6
4.6
35.05
35.12
g/l
0.05
124
753
19
23
8.95
9.29
4.4
2.0
4.92
4.16
nmol/l
0.11
19
23
99
571
2.36
8.62
3.7
3.3
35.91
30.27
u/l
0.79
94
550
133
922
2.16
6.85
7.2
6.7
1.21
1.21
mmol/l
0.11
111
788
129
885
2.14
6.82
10.2
12.7
1.21
1.23
inr
0.10
43
255
18
47
4.09
6.40
1.2
1.3
—
—
—
0
0
54
280
2.24
5.70
2.6
2.1
12.83
12.80
umol/l
0.01
48
259
82
525
1.91
4.79
3.4
2.9
0.21
0.66
e6/l
1.94
57
388
46
239
2.18
4.78
2.8
2.2
19.84
22.17
%
0.55
38
209
35
162
2.39
4.76
4.1
6.3
1.24
1.36
mmol/l
0.31
35
156
140
1067
1.89
4.69
5.4
5.3
7.10
6.65
mmol/l
1.08
134
995
25
99
2.73
4.66
5.6
4.7
24.32
25.17
mmol/l
0.55
25
99
116
843
1.82
4.43
7.8
6.1
1.21
1.21
mmol/l
0.06
111
772
173
1431
2.07
4.36
13.0
7.5
84.36
78.81
u/l
0.71
168
1338
45
242
2.09
4.26
5.0
6.3
103.56
103.78
mmol/l
0.14
45
242
58
343
1.95
4.22
3.4
3.6
177.43
107.74
ng/l
0.23
46
279
11
22
5.21
4.06
1.4
1.4
—
—
—
0
0
132
1022
1.76
3.85
17.0
9.5
4.02
4.09
e9/l
0.14
111
907
94
664
1.74
3.79
3.4
3.0
—
—
—
0
0
101
736
1.70
3.58
3.5
2.5
132.39
119.45
ug/l
0.30
94
678
101
738
1.70
3.53
3.0
2.2
79.78
78.47
nmol/l
0.17
90
653
49
298
1.83
3.22
3.2
2.9
4.99
2.82
e6/l
0.25
19
158
27
136
2.13
3.01
1.5
1.6
—
—
—
0
0
110
859
1.57
2.73
3.0
2.6
—
—
—
0
0
36
209
1.87
2.72
1.7
1.9
—
—
—
0
0
96
729
1.57
2.68
2.2
1.9
98.51
96.64
pmol/l
0.13
48
353
10
31
3.33
2.55
1.8
1.4
226.40
310.19
mu/l
—
10
31
34
199
1.84
2.51
4.6
3.4
—
—
—
0
0
176
1553
1.73
2.50
31.4
17.4
15.16
15.15
%
0.01
171
1528
45
287
1.72
2.50
1.7
2.0
—
—
—
0
0
9
216
0.39
2.48
11.4
8.2
—
—
—
0
0
44
282
1.70
2.40
1.8
1.8
29.67
29.42
s
0.13
44
274
10
33
3.13
2.39
1.5
1.5
—
—
—
0
0
10
33
3.13
2.39
1.5
1.5
—
—
—
0
0
36
218
1.78
2.38
4.1
8.9
0.87
1.48
mmol/l
0.42
26
179
51
344
1.63
2.29
5.8
3.0
2.44
2.46
mmol/l
0.43
46
303
48
320
1.64
2.25
3.2
2.7
0.52
1.12
e6/l
1.55
17
178
34
206
1.77
2.25
1.7
1.8
—
—
—
0
0
73
542
1.53
2.17
3.8
3.7
4.11
10.28
mg/mmol
1.37
44
335
19
97
2.05
2.07
3.6
3.5
4.17
4.39
pmol/l
0.75
19
83
199
1856
1.97
1.88
25.2
17.2
139.30
139.77
mmol/l
1.69
194
1807
134
1146
1.45
1.86
4.5
3.2
63.14
50.74
u/l
0.63
125
1068
6
17
3.60
1.85
1.0
1.0
—
—
—
0
0
25
147
1.79
1.83
2.6
2.8
4.10
4.19
kpa
0.12
25
142
58
425
1.50
1.80
2.9
2.0
3.52
3.20
mg/l
0.28
53
367
15
74
2.10
1.80
1.1
2.2
—
—
—
0
0
199
1862
1.92
1.76
25.6
17.3
3.95
3.98
mmol/l
0.64
194
1812
192
1780
1.74
1.73
25.0
14.7
28.34
22.51
mg/l
1.44
165
1399
5
13
3.91
1.72
1.0
1.1
329.00
299.02
u/l
—
5
13
63
474
1.47
1.71
3.0
2.7
327.81
8049.05
umol/l
2.74
57
408
6
19
3.22
1.67
1.3
1.7
—
—
—
0
0
6
19
3.22
1.67
1.3
1.7
—
—
—
0
0
10
42
2.45
1.64
1.6
1.5
—
—
—
0
0
10
44
2.33
1.58
1.8
1.4
—
—
—
0
0
58
436
1.45
1.57
1.6
1.5
20.41
21.10
nmol/l
0.13
52
360
17
93
1.90
1.56
1.1
1.0
—
—
—
0
0
7
27
2.64
1.53
2.3
1.1
—
—
nmol/l
—
0
0
7
28
2.55
1.46
1.3
1.9
—
—
—
0
0
7
28
2.55
1.46
1.3
1.9
—
—
—
0
0
55
415
1.44
1.46
3.0
2.5
—
—
—
0
0
11
53
2.13
1.41
1.3
1.2
—
—
—
0
0
11
54
2.09
1.35
1.2
1.7
—
—
—
0
0
106
903
1.34
1.33
3.8
3.8
0.00
0.00
estimate
-0.00
26
189
9
44
2.09
1.28
1.2
1.7
—
—
—
0
0
9
44
2.09
1.28
1.3
1.6
—
—
—
0
0
5
20
2.53
1.15
1.4
1.2
—
—
—
0
0
105
915
1.29
1.05
5.0
5.1
0.00
0.00
estimate
-0.00
22
174
17
107
1.64
1.03
1.4
1.7
—
—
—
0
0
17
108
1.62
1.00
1.5
1.4
—
—
—
0
0
180
1692
1.39
1.00
24.7
13.9
77.60
78.41
ml/min/173m2
0.19
155
1387
5
23
2.20
0.98
1.2
1.3
—
—
—
0
0
105
924
1.27
0.94
3.8
3.8
0.00
0.00
estimate
-0.00
24
170
6
27
2.26
0.94
1.2
1.0
—
—
—
0
0
8
43
1.89
0.88
1.4
1.6
—
—
—
0
0
8
45
1.81
0.85
2.0
1.8
—
—
—
0
0
6
31
1.96
0.85
1.5
1.6
—
—
—
0
0
8
46
1.77
0.83
1.4
1.2
—
—
—
0
0
6
33
1.84
0.79
1.3
1.7
—
—
—
0
0
0
27
0.00
0.78
0.0
3.5
—
27.16
—
0
8
49
402
1.28
0.76
1.3
1.2
0.53
1.85
u/ml
1.62
12
118
197
1898
1.45
0.76
16.6
10.8
27.18
24.60
u/l
1.09
191
1831
5
24
2.11
0.75
1.4
1.7
—
—
—
0
0
7
38
1.87
0.74
1.1
1.3
2.43
164.07
e6/l
—
7
30
7
38
1.87
0.74
1.1
1.1
0.57
2.41
e6/l
—
7
29
7
38
1.87
0.74
1.6
1.3
—
—
—
0
0
7
40
1.77
0.72
1.6
1.1
—
—
—
0
0
5
27
1.87
0.69
1.6
1.3
—
—
—
0
0
5
28
1.80
0.66
2.6
3.8
44.40
60.71
%
—
5
28
5
28
1.80
0.66
1.6
1.7
—
—
—
0
0
48
405
1.24
0.60
2.1
1.6
1.24
1.37
mg/l
0.12
42
318
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
16
215
0.72
0.56
3.9
4.5
28.22
32.50
%
—
9
145
6
39
1.55
0.53
1.3
1.4
—
—
—
0
0
33
271
1.26
0.52
1.5
1.4
—
—
—
0
0
173
1658
1.22
0.52
5.2
4.8
1.93
1.94
mu/l
0.03
163
1505
58
511
1.18
0.48
1.9
1.7
1.43
1.33
mmol/l
0.42
52
428
176
1697
1.20
0.45
6.6
5.8
40.82
40.15
mmol/mol
0.42
166
1578
14
104
1.37
0.44
1.1
1.1
340.99
149.42
iu/ml
—
7
44
8
56
1.44
0.43
1.3
2.6
0.00
0.00
g/l
—
8
56
8
56
1.44
0.43
1.3
2.6
0.00
0.00
g/l
—
8
56
56
497
1.17
0.42
4.3
3.9
0.00
0.00
estimate
-0.00
23
168
8
57
1.42
0.42
1.3
2.6
0.00
0.00
g/l
—
8
57
78
711
1.15
0.42
3.9
3.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
66.75
—
0
12
200
1958
1.31
0.40
36.7
21.8
39.17
39.90
%
0.85
188
1837
200
1958
1.31
0.40
36.6
21.7
4.42
4.45
e12/l
0.27
195
1899
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
145
1389
1.13
0.35
4.3
4.0
14.59
14.81
pmol/l
0.48
133
1249
6
45
1.34
0.34
1.0
1.2
—
—
—
0
0
182
1774
1.17
0.31
4.6
4.7
5.98
5.98
mmol/l
0.00
169
1624
7
53
1.33
0.31
2.3
2.4
—
—
—
0
0
57
520
1.13
0.30
5.0
5.1
2.16
2.70
ug/l
0.33
51
459
33
290
1.16
0.29
1.5
1.4
—
—
—
0
0
8
63
1.28
0.28
1.1
1.2
—
—
—
0
0
34
302
1.15
0.26
1.2
1.3
17.24
12.19
u/ml
0.15
16
115
40
361
1.13
0.25
1.9
1.6
1200.50
1247.56
nmol/l
0.11
30
275
12
96
1.26
0.25
2.5
2.6
0.43
0.69
%
2.27
12
96
35
314
1.14
0.24
2.7
3.0
0.76
0.74
ug/l
0.03
24
212
166
1700
0.90
0.23
3.8
4.1
1.20
1.27
mmol/l
0.95
154
1552
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
173
1763
0.90
0.19
4.4
4.5
1.44
1.52
mmol/l
1.65
159
1616
106
1019
1.08
0.19
3.0
2.8
—
—
—
0
0
12
100
1.21
0.18
2.5
2.6
1.06
1.14
%
0.09
12
100
45
418
1.10
0.18
4.5
4.3
23.34
20.79
%
0.40
17
200
7
62
1.13
0.17
1.1
1.2
—
—
—
0
0
7
63
1.11
0.17
1.3
2.1
—
—
—
0
0
11
128
0.85
0.14
1.5
1.8
—
—
—
0
0
175
1775
0.92
0.13
4.4
4.6
4.50
4.65
mmol/l
1.32
161
1636
29
310
0.93
0.10
1.3
1.3
13.39
39.37
iu/ml
2.91
14
109
6
55
1.09
0.09
2.0
1.3
—
—
—
0
0
5
64
0.78
0.08
1.6
1.6
—
—
—
0
0
11
98
1.13
0.08
1.1
1.3
—
—
—
0
0
72
740
0.96
0.07
3.8
3.9
40.85
42.70
ng/l
0.03
48
538
11
120
0.91
0.05
1.5
1.6
—
—
—
0
0
40
406
0.98
0.00
2.1
1.7
398.77
448.59
pmol/l
0.77
30
333
57
574
0.99
0.00
2.8
3.2
1609.75
1146.76
ng/l
0.26
49
489
181
1813
0.99
0.00
5.1
5.2
2.64
2.71
mmol/l
0.53
165
1664
14
135
1.04
0.00
1.5
1.7
—
—
—
0
0
16
158
1.01
0.00
1.8
2.7
72.43
62.06
ml/min/173m2
—
7
66
0
5
0.00
0.00
0.0
1.0
—
11.91
—
0
5
0
5
0.00
0.00
0.0
1.0
—
1.21
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
-0.00
1.8
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
59
1.02
-0.00
1.3
1.9
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_DIGESTIVE_NOS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_DIGESTIVE_NOS | 1.908 [1.49, 2.44] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.146 |
During the follow-up period (1.1.1998 — 31.12.2019), 158 out of 500 females with CD2_BENIGN_DIGESTIVE_NOS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_DIGESTIVE_NOS | 1.995 [1.48, 2.68] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 139 out of 332 males with CD2_BENIGN_DIGESTIVE_NOS died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_DIGESTIVE_NOS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.224% | 0.335% |
| 5 | 1.08% | 2.077% |
| 10 | 2.401% | 5.039% |
| 15 | 4.887% | 9.237% |
| 20 | 8.89% | 15.301% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_DIGESTIVE_NOS – Benign neoplasm: Ill-defined sites within the digestive system
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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