Other and unspecified spinal muscular atrophies

G6_SPINAMUSCOTH

spinal muscular atrophy: Spinal muscular atrophy is a disorder of spinal motor neurons characterized clinically by the development of muscle weakness and atrophy.

Suggest a new description

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G12.8, G12.9, G13* Hospital discharge: ICD-9 — 335 Hospital discharge: ICD-8 — 34829\|3489 Hospital discharge: excluded ICD-9 — 3350A\|3351A\|3352A Cause of death: ICD-10 — G12.8, G12.9, G13* Cause of death: ICD-9 — 335 Cause of death: ICD-8 — 34829\|3489 2 out of 7 registries used, show all original rules.	294
4. Check minimum number of events None	294
5. Include endpoints None	294
6. Filter based on genotype QC (FinnGen only)	294

Control definitions (FinnGen only)

Control exclude: G6_NEUATR

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	G6_SPINAMUSCOTH
CONTROL_EXCLUDE	G6_NEUATR
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G12[8-9]\|G13
HD_ICD_9	335
HD_ICD_8	34829\|3489
HD_ICD_10_EXCL
HD_ICD_9_EXCL	3350A\|3351A\|3352A
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G12[8-9]\|G13
COD_ICD_9	335
COD_ICD_8	34829\|3489
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other and unspecified spinal muscular atrophies based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	3434	1501	1850
Only index persons	1766	795	971
Unadjusted period prevalence (%)
Whole population	0.05	0.04	0.05
Only index persons	0.03	0.03	0.04
Median age at first event (years)
Whole population	60.57	61.22	59.94
Only index persons	56.32	57.03	55.75

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	294	112	182
Unadjusted period prevalence (%)	0.06	0.04	0.08
Median age at first event (years)	59.86	55.49	62.55

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
272: Matched controls
2720

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

G12.9

ICD-10 Finland

Spinal muscular atrophy, unspecified

+∞

143.9

125

G12.8

ICD-10 Finland

Other spinal muscular atrophies and related syndromes

+∞

94.4

G12.2

ICD-10 Finland

Motor neuron disease

+∞

65.3

34899

ICD-8 Finland

Motor neurone disease, Other and unspecified manifestations

+∞

26.5

G12.1

ICD-10 Finland

Other inherited spinal muscular atrophy

+∞

24.3

G62.9

ICD-10 Finland

Polyneuropathy, unspecified

13.2

23.1

N03AE01

ATC

clonazepam; systemic

8.4

22.2

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

6.2

18.9

105

G72.9

ICD-10 Finland

Myopathy, unspecified

35.7

18.3

TAB00

NOMESCO Finland

Lumbar puncture

9.9

17.8

N99

ICPC

Neurological disease other

17.0

14.2

N07XX02

ATC

riluzole; oral

+∞

12.6

3352A

ICD-9 Finland

Anterior horn cell disease, Motor neuron disease[SCLEROSIS LATERALIS AMYOTROPHICA]

+∞

11.5

NJ3CG

NOMESCO Finland

Extensive MRI examination of extremities with median high magnet

29.4

10.8

R1250

NOMESCO Finland

Evaluation of functional capability

12.0

10.2

N03AX12

ATC

gabapentin; oral

3.3

10.0

189

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

4.3

9.7

L28

ICPC

Limited function/disability (L)

2.9

9.6

261

NJ3BG

NOMESCO Finland

MRI examination of extremities with high intensity magnet

+∞

9.4

3351X

ICD-9 Finland

Anterior horn cell disease, Spinal muscular atrophy[ATROPHIA MUSCULORUM SPINALIS NUD]

+∞

9.4

34898

ICD-8 Finland

Motor neurone disease, Alii definiti

+∞

9.4

G13.0

ICD-10 Finland

Paraneoplastic neuromyopathy and neuropathy

+∞

9.4

N28

ICPC

Limited function/disability (N)

10.1

9.4

M03BX01

ATC

baclofen; systemic

9.9

8.4

J96.1

ICD-10 Finland

Chronic respiratory failure

7.2

8.2

R47.1

ICD-10 Finland

Dysarthria and anarthria

12.2

8.2

N29

ICPC

Neurological sympt/complt other

9.4

8.2

G60.0

ICD-10 Finland

Hereditary motor and sensory neuropathy

46.3

7.8

NXL00

NOMESCO Finland

Biopsy of muscle

25.8

7.6

Z50.1

ICD-10 Finland

Other physical therapy

4.6

7.6

G71.08

ICD-10 Finland

Other muscular dystrophy

82.2

7.5

M62.5

ICD-10 Finland

Muscle wasting and atrophy, not elsewhere classified

82.2

7.5

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

2.6

7.4

258

NGA20

NOMESCO Finland

Exploration of soft tissue knee or lower leg, open

+∞

7.3

SPAT1229

SPAT

Assessment of need for aid

3.2

7.1

128

Z03.3

ICD-10 Finland

Observation for suspected nervous system disorder

3.9

6.9

R26.8

ICD-10 Finland

Other and unspecified abnormalities of gait and mobility

7.5

6.8

R25.3

ICD-10 Finland

Fasciculation

41.1

6.8

R13

ICD-10 Finland

Dysphagia

3.5

6.4

G13.2*E03.9

ICD-10 Finland

Systemic atrophy primarily affecting central nervous system in myxoedema

+∞

6.3

G12.0

ICD-10 Finland

Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

147

3.17

9.64

2.4

—

4.6

—

(4027681)

8.30

8.92

1.4

1.1

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

9.38

8.13

1.3

1.0

1.9

1.8

mmol/l

—

(1616796) Gas panel - Central venous blood

4.49

8.07

4.1

4.2

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

5.62

6.83

1.2

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

5.64

6.34

1.2

1.0

—

(3044290) Cell count panel - Cerebral spinal fluid

4.13

6.26

1.6

1.2

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

4.99

6.03

1.2

1.0

—

(3012320) Pathologist interpretation of Cerebral spinal fluid tests

13.65

5.10

1.1

1.2

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

14.29

4.59

1.1

1.0

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

14.29

4.59

1.1

1.0

—

(40767503) Oxygen content in Capillary blood by calculation

3.17

3.86

2.9

2.2

17.9

15.7

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

5.76

3.68

1.3

1.0

—

(3009343) pH of Capillary blood

169

2.07

3.45

4.2

3.5

7.4

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.19

3.41

1.2

1.4

—

(3016018) Differential panel - Cerebral spinal fluid

5.12

3.39

1.3

1.1

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

192

2200

0.63

3.30

4.9

5.2

2.7

mmol/l

0.75

169

2009

(3004588) Protein electrophoresis panel - Serum or Plasma

175

2.00

3.15

2.3

2.6

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

7.63

3.07

1.3

1.0

—

(3021901) Oxygen saturation in Capillary blood

2.83

3.03

3.4

2.3

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

177

2047

0.66

2.95

7.5

6.2

40.1

40.7

mmol/mol

0.37

159

1894

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

5.49

2.88

3.3

2.0

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

6.78

2.88

1.3

1.2

—

(3010813) Leukocytes [#/volume] in Blood

221

2436

0.63

2.87

28.8

22.9

6.9

6.8

e9/l

0.32

215

2357

(3026361) Erythrocytes [#/volume] in Blood

221

2436

0.63

2.87

28.8

22.8

4.4

4.5

e12/l

0.26

216

2356

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

189

2152

0.66

2.85

4.5

4.6

4.5

mmol/l

0.95

169

1981

(3026782) Osmolality of Urine

480

1.60

2.82

4.9

2.9

571.7

559.9

mosm/kgh2o

0.16

408

(3037522) Nuclear Ab [Titer] in Serum

267

1.76

2.80

1.4

1.3

420.0

470.0

titre

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

8.45

2.76

1.4

1.0

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

8.45

2.76

1.4

1.0

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

8.45

2.76

1.4

1.0

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

188

2136

0.67

2.71

4.4

4.6

1.5

1.4

mmol/l

0.37

166

1950

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

6.10

2.71

1.3

1.1

—

(3044889) 12 lead EKG panel

129

1572

0.68

2.68

3.9

4.2

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

107

2.14

2.65

2.4

3.2

1.1

1.2

0.23

107

(3009508) Creatinine [Moles/volume] in Urine

730

0.61

2.64

3.3

3.2

6.8

7.6

mmol/l

0.77

610

(3022313) Gas panel - Capillary blood

123

2.04

2.54

3.9

3.7

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

609

0.59

2.52

1.6

1.7

1.3

mmol/l

0.35

511

(3028626) Oxygen [Partial pressure] in Capillary blood

2.36

2.46

3.2

3.1

8.6

8.2

kpa

0.39

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

818

0.64

2.44

4.1

4.6

24.6

21.7

0.81

409

(3000850) Epithelial cells [#/volume] in Urine

497

1.54

2.41

4.0

2.7

6.8

4.7

e6/l

0.41

436

(3024354) Oxygen [Partial pressure] in Venous blood

178

1.83

2.37

2.6

3.7

4.4

kpa

0.07

170

(3030467) Casts [#/volume] in Urine by Automated count

650

1.48

2.35

4.9

3.3

0.2

0.5

e6/l

1.65

488

(3012516) Albumin [Mass/volume] in Urine

699

0.63

2.31

3.5

3.2

1201.8

329.5

mg/l

0.33

459

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

191

2142

0.69

2.30

5.1

4.8

5.9

6.0

mmol/l

1.10

173

1948

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.62

2.30

1.2

1.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

183

2064

0.70

2.24

4.2

4.1

1.4

1.3

mmol/l

0.74

163

1871

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

107

842

1.43

2.18

5.3

3.4

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

391

1.53

2.07

3.7

3.0

1.0

e6/l

0.09

231

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

2.41

1.97

1.6

1.2

—

(3002032) Base excess in Venous blood by calculation

213

1.67

1.96

3.1

4.6

3.1

1.8

mmol/l

1.22

167

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

107

856

1.39

1.95

5.3

3.9

—

(3006653) Thiamine [Moles/volume] in Blood

4.60

1.95

1.0

1.6

141.4

127.7

nmol/l

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

3.80

1.94

1.0

1.2

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

214

1.67

1.93

3.1

4.6

6.0

5.7

kpa

0.91

207

(3012544) pH of Venous blood

224

1.64

1.87

3.1

4.6

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

4.22

1.83

1.0

3.3

29.4

30.0

umol/l

—

(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma

109

1.90

1.82

1.1

1.2

63.9

129.4

iu/ml

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

186

2062

0.73

1.75

18.7

14.6

86.6

77.8

ml/min/173m2

4.20

168

1711

(3026389) Candida sp identified in Specimen by Organism specific culture

2.96

1.73

1.3

—

(3023410) Appearance of Cerebral spinal fluid

2.84

1.66

2.0

1.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

128

1076

1.34

1.65

7.1

5.0

0.0

estimate

0.00

220

(1761482) Bacteria [#/volume] in Urine by Culture

2.05

1.62

4.2

5.1

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

106

869

1.34

1.61

2.4

2.2

81.1

77.4

nmol/l

0.67

770

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

161

1.67

1.59

1.6

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

3.04

1.59

1.0

1.1

—

(36304419) Bacteria [Presence] in Urine

620

1.37

1.58

4.4

3.3

—

(4034850)

1.97

1.57

10.3

11.1

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

513

1.40

1.55

1.8

511.5

22717065.9

pmol/l

0.79

427

(3020682) Albumin/Creatinine [Ratio] in Urine

735

0.71

1.55

5.1

3.9

2.9

8.2

mg/mmol

3.30

473

(3019230) Fractional oxyhemoglobin in Venous blood

2.46

1.55

1.4

2.6

58.8

58.9

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

1.53

0.0

1.3

—

(3026008) Bacteria identified in Urine by Culture

669

1.36

1.53

3.6

3.0

—

(3009261) Glucose [Presence] in Urine by Test strip

129

1095

1.32

1.53

5.1

3.8

0.0

estimate

0.00

206

(3035637) Corticotropin [Mass/volume] in Plasma

2.89

1.51

1.8

1.4

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

134

1150

1.30

1.44

8.3

7.1

1.2

mmol/l

0.15

106

962

(3011412) CD3 cells [#/volume] in Blood

2.76

1.44

3.7

1.7

1.4

0.8

e9/l

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

174

1.61

1.43

4.0

2.7

99.9

61.7

ml/min/173m2

0.39

(3035350) Ketones [Presence] in Urine by Test strip

126

1074

1.30

1.42

4.9

3.8

0.0

estimate

0.00

219

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

162

0.48

1.40

1.8

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.64

1.37

1.0

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

147

0.46

1.36

1.0

1.9

—

(40761511) CBC panel - Blood by Automated count

214

2296

0.75

1.35

19.4

14.5

—

(3017732) Neutrophils [#/volume] in Blood

153

1.62

1.33

5.5

2.7

3.7

3.8

e9/l

0.12

117

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

2.53

1.31

1.0

1.9

—

(3018095) Leukocytes [#/volume] in Urine

816

1.30

5.8

4.0

49.8

93.2

e6/l

0.83

595

(3019309) Folate [Moles/volume] in Red Blood Cells

465

1.36

1.29

1.8

1.7

1249.6

1202.1

nmol/l

0.14

349

(3047007) Chlamydophila sp Ab [Presence] in Serum

2.81

1.29

1.0

1.2

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

2.81

1.29

1.4

1.3

—

(21494755) Public health laboratory ask at order entry panel

160

0.49

1.28

1.1

1.3

—

(3045424) Erythrocytes [Presence] in Urine

2.32

1.28

3.0

1.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

107

1247

0.78

1.27

2.4

2.8

—

(3023368) Bacteria identified in Blood by Culture

685

1.29

1.17

4.5

4.4

—

(3049717) Cytology report of Urine Cyto stain

111

0.44

1.15

3.6

2.9

—

(3019150) Specific gravity of Urine by Refractometry

492

1.33

1.15

5.0

4.1

1.0

kg/l

0.03

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

2.36

1.13

1.0

1.1

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

2.36

1.13

2.0

1.8

10.6

16.9

ug/l

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

1.85

1.10

1.2

—

(3020891) Body temperature

1.72

1.10

5.7

4.4

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

2.40

1.09

4.0

3.6

28.8

63.3

u/ml

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

2.40

1.09

1.4

1.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

607

1.29

1.09

5.1

3.4

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

1024

0.79

1.09

5.3

28.0

2.9

ug/l

0.93

898

(3021788) Differential panel - Synovial fluid

2.22

1.09

1.4

1.3

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

588

0.74

1.06

3.1

0.9

0.8

ug/l

0.95

392

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

373

1.34

1.03

4.6

3.2

1.9

1.7

e6/l

0.08

215

(3002582) Erythrocytes [#/volume] in Urine

715

1.27

1.02

5.6

3.5

38.3

155.7

e6/l

0.70

557

(3000330) Specific gravity of Urine by Test strip

115

1.60

1.02

5.3

4.2

—

(3037756) Immunofixation for Serum or Plasma

1.88

0.98

2.2

1.5

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.97

0.97

1.3

1.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.82

0.97

1.2

1.3

—

(3009542) Hematocrit [Volume Fraction] of Blood

181

1953

0.81

0.97

18.0

16.9

38.0

39.6

0.87

105

1341

(3002256) Pathology report gross observation

291

0.66

0.97

1.4

1.3

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

1.79

0.95

1.1

—

14.4

—

(3017181) Myelocytes/100 leukocytes in Blood

203

1.42

0.91

4.8

4.6

1.8

0.8

0.54

(3021440) Promyelocytes/100 leukocytes in Blood

187

1.43

0.89

4.9

4.8

0.4

0.1

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

1.95

0.85

2.8

4.5

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

210

2219

0.81

0.84

20.5

15.7

26.1

24.5

mg/l

0.22

181

1787

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

340

1.31

0.84

1.3

1.0

13.9

u/ml

2.31

134

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.79

0.0

1.1

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.68

0.79

1.1

1.6

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.79

0.0

3.2

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

1.78

0.76

1.0

1.3

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

149

1362

1.19

0.76

5.3

5.1

6.6

6.8

mmol/l

0.93

137

1270

(3018418) pH of Serum or Plasma

690

1.22

0.76

4.7

4.0

7.4

0.27

133

(3017143) Hepatitis C virus Ab [Presence] in Serum

242

0.68

0.76

1.1

1.5

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

133

1206

1.19

0.74

5.2

6.6

11.9

11.8

umol/l

0.01

125

1139

(3007853) Bacteria identified in Skin by Aerobe culture

265

1.32

0.74

2.6

1.8

—

(3041354) Potassium [Moles/volume] in Venous blood

1.86

0.74

2.4

3.1

3.9

4.1

mmol/l

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

1.86

0.74

2.4

3.1

—

(3035285) Chloride [Moles/volume] in Venous blood

1.86

0.74

2.4

3.1

108.7

105.0

mmol/l

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

285

0.72

0.73

8.3

7.7

—

(3032080) INR in Blood by Coagulation assay

109

973

1.19

0.72

12.9

9.7

1.3

1.2

inr

0.03

276

(3021589) Normoblasts [#/volume] in Blood

108

965

1.19

0.71

10.5

10.3

0.0

e9/l

0.42

801

(3024928) Oxygen saturation in Venous blood

1.72

0.70

1.3

4.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

481

1.23

0.67

6.1

5.6

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.52

0.67

1.0

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

342

1.27

0.67

1.4

1.3

28.8

38.4

iu/ml

0.31

110

(3022806) Fractional oxyhemoglobin in Capillary blood

1.80

0.66

2.2

1.3

85.8

89.3

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.61

0.65

1.1

1.6

—

(3023520) Reticulocytes [#/volume] in Blood

235

1.31

0.64

1.9

2.6

73.0

67.6

e9/l

0.40

189

(3044941) Cell count panel - Synovial fluid

1.74

0.64

1.8

1.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

147

1.39

0.63

1.8

1.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.65

0.62

1.1

1.8

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.61

0.62

1.1

1.7

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

1.68

0.61

1.4

1.3

—

(3000991) Gas panel - Venous blood

192

1.33

0.61

5.4

8.3

—

(4035726)

201

1.32

0.61

1.3

1.5

—

(40760888) Immunoglobulin light chains.free panel - Serum

1.58

0.61

5.8

5.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

162

0.67

0.60

1.3

2.0

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

1.73

0.58

1.0

1.4

—

(3029937) Albumin [Presence] in Urine by Test strip

613

1.19

0.57

5.6

4.0

0.0

estimate

0.00

209

(3013139) Helicobacter pylori Ag [Presence] in Stool

122

0.65

0.56

1.3

1.2

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

1.63

0.56

7.0

2.3

4.2

5.0

e9/l

—

(3026493) Urate [Moles/volume] in Serum or Plasma

615

1.18

0.55

3.6

2.8

10618.7

8032.4

umol/l

0.13

518

(3025159) Blasts/100 leukocytes in Blood

178

1.32

0.55

4.3

4.9

0.0

0.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

259

0.76

0.54

1.3

1.5

—

(3004809) Band form neutrophils/100 leukocytes in Blood

1.55

0.53

6.3

2.9

0.8

1.3

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

1.55

0.53

8.5

2.9

62.8

58.7

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

302

0.78

0.53

1.3

1.7

—

(40768797) Stomach Pathology biopsy report

302

0.78

0.53

1.2

1.3

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

439

1.20

0.51

2.4

3.1

2.4

mmol/l

0.24

378

(40761535) Cells panel - Urine sediment

181

1.29

0.50

4.0

3.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

169

1596

1.14

0.49

4.2

3.7

15.1

14.8

pmol/l

0.91

159

1418

(3013512) EKG study

728

1.16

0.49

4.9

4.0

—

(3013115) Eosinophils [#/volume] in Blood

126

1168

1.14

0.49

6.9

5.9

0.2

e9/l

0.18

119

1041

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

1.53

0.48

1.4

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

1.53

0.48

1.4

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

1.53

0.48

1.1

1.4

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

246

1.24

0.48

5.4

3.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

112

1.36

0.45

1.3

1.8

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

295

0.80

0.45

4.8

4.7

30.8

31.6

0.13

199

(40758558) Short blood count panel - Blood

541

1.16

0.44

6.8

7.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

1.62

0.43

1.4

1.3

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

1.62

0.43

1.4

1.3

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

1.62

0.43

1.4

1.3

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

1.62

0.43

1.4

1.3

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

1.57

0.42

1.4

1.7

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

1.57

0.42

1.4

1.3

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

1.57

0.42

1.2

2.0

35.4

34.3

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.44

0.42

1.3

2.0

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

238

0.78

0.42

12.3

9.4

126.5

120.7

g/l

0.48

233

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

0.41

0.0

1.8

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

0.41

0.0

1.8

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.41

0.0

1.5

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

1.37

0.41

1.1

1.4

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.37

0.41

1.3

1.2

—

(3004451) EKG impression Narrative

0.00

0.41

0.0

1.3

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.41

0.0

3.6

—

(40768441) Liver Pathology biopsy report

0.00

0.41

0.0

1.3

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.41

0.0

1.2

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.41

0.0

1.2

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.41

0.0

1.2

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

106

1.34

0.40

2.0

2.4

3.7

g/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

106

1.34

0.40

2.0

2.4

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

106

1.34

0.40

2.0

2.4

7.7

7.4

g/l

—

(3042631) Mycobacterium sp identified in Specimen

1.44

0.39

1.0

2.7

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.36

0.38

2.3

1.6

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

1.40

0.38

2.6

3.3

82.8

35.4

u/ml

—

(3000494) Fungus identified in Specimen by Culture

267

0.81

0.38

1.5

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

1.44

0.35

1.2

1.6

—

(42870588) Differential panel, method unspecified - Blood

754

1.12

0.35

5.9

5.6

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

101

941

1.11

0.35

2.1

2.0

93.9

95.0

pmol/l

0.07

496

(40761536) Microorganisms panel - Urine sediment

191

1.22

0.34

4.4

3.6

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.68

0.33

1.2

3.3

—

(3022145) Colonoscopy Study observation

252

0.82

0.33

1.2

1.3

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.32

0.32

2.4

1.8

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.33

0.31

1.3

1.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

141

0.77

0.30

1.4

1.3

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

1.26

0.29

1.9

2.1

9.7

13.1

mg/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

102

959

1.10

0.29

4.0

3.9

92.9

44.9

ng/l

0.54

698

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

395

1.13

0.28

2.2

1.9

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

1.30

0.28

1.0

1.3

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

618

1.11

0.28

2.2

2.1

3.3

3.1

mg/l

0.24

535

(3007164) IgA [Mass/volume] in Serum or Plasma

425

1.13

0.27

1.4

2.6

g/l

0.10

253

(3003694) ABO and Rh group [Type] in Blood

548

0.89

0.27

1.4

—

(1002224) Polysomnography panel

0.69

0.26

1.0

1.1

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.68

0.26

6.0

2.5

0.4

0.3

u/ml

—

(3008898) HLA-B27 [Presence]

1.26

0.26

1.0

1.1

—

(3001604) Monocytes [#/volume] in Blood

118

1126

1.08

0.24

6.4

5.7

0.6

e9/l

0.49

110

988

(3011397) Hemoglobin [Presence] in Urine by Test strip

488

1.10

0.23

4.6

3.9

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

387

0.89

0.22

2.1

2.0

29.7

29.2

0.33

377

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

110

1050

1.08

0.22

8.0

6.2

1.2

mmol/l

0.50

102

939

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

107

1021

1.08

0.21

4.7

4.4

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3003129) Base excess in Capillary blood by calculation

0.00

0.21

0.0

1.1

—

3.8

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.21

0.0

1.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(44813793)

0.00

0.21

0.0

1.0

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.21

0.0

1.5

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3016436) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma

0.00

0.21

0.0

2.1

—

216.2

—

(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood

0.00

0.21

0.0

1.2

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.2

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.2

—

(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture

0.00

0.21

0.0

1.2

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

8.1

—

0.6

—

(3019198) Lymphocytes [#/volume] in Blood

120

1151

1.07

0.21

6.7

5.9

1.7

2.0

e9/l

1.08

111

1029

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

0.21

0.0

2.0

—

(3006315) Basophils [#/volume] in Blood

118

1132

1.07

0.20

6.5

5.7

0.0

e9/l

0.60

110

1000

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

1.26

0.20

1.2

1.3

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.26

0.20

1.2

1.4

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.20

0.0

1.3

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.20

0.0

1.4

—

1.1

—

(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum

0.00

0.20

0.0

1.2

—

11.2

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

1.23

0.20

1.3

1.2

10.0

8.4

u/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

154

0.84

0.19

1.2

1.4

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

454

0.91

0.18

3.1

3.8

69.5

268.9

ng/l

1.39

362

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.19

0.18

1.7

1.5

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.17

0.18

1.7

1.6

—

(1761868) Lipid panel - Serum or Plasma

749

0.93

0.17

3.5

3.1

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

751

1.07

0.17

2.8

3.4

2.3

mmol/l

0.24

655

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.75

0.17

1.0

1.8

—

(3044640) Blood type and Crossmatch panel - Blood

703

1.07

0.17

2.6

2.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

195

1989

0.94

0.16

5.1

4.5

1.8

2.0

mu/l

1.07

182

1784

(3021960) Folate [Moles/volume] in Serum or Plasma

588

1.07

0.15

1.7

1.6

17.9

20.4

nmol/l

0.86

495

(36660697) Celiac disease serology panel - Serum

170

1.13

0.14

1.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

201

0.89

0.14

1.7

1.6

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

483

1.07

0.13

1.8

1.9

1.5

mg/l

0.19

384

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

527

0.94

0.12

2.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

134

1308

1.04

0.12

9.2

9.5

4.4

4.1

e9/l

0.41

125

1155

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

250

1.09

0.11

1.4

—

(3022621) pH of Urine by Test strip

157

0.89

0.11

3.3

2.5

—

(3019225) pH of Specimen

229

0.91

0.11

5.0

3.9

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

1.11

0.10

1.8

1.5

—

(40768443) Skin Pathology biopsy report

1.15

0.09

1.6

1.2

—

(3022096) Basophils/100 leukocytes in Blood

106

1034

1.04

0.09

7.2

5.9

0.6

0.25

101

971

(3037467) Urinalysis macro (dipstick) panel - Urine

155

1524

1.04

0.09

5.5

4.1

—

(40768804) Tissue Pathology biopsy report

873

0.96

0.08

2.3

2.1

—

(3000492) Spirometry study

195

1.08

0.08

1.8

1.4

—

(3045414) Leukocytes [Presence] in Urine

1.14

0.08

2.8

1.9

—

(40768800) Prostate Pathology biopsy report

1.06

0.08

1.0

1.1

—

(3052851) Hemolysis interference index of Serum or Plasma

0.84

0.07

3.7

3.3

—

(3002179) Metamyelocytes/100 leukocytes in Blood

186

1.08

0.07

3.5

4.5

3.1

0.4

—

(3025941) Bacteria identified in Stool by Culture

118

1.11

0.07

1.4

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

275

1.06

0.07

2.0

1.8

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

453

1.04

0.07

1.2

0.8

1.0

u/ml

0.45

114

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

142

1441

0.97

0.06

3.2

52.5

51.3

u/l

0.04

129

1339

(3004716) Salmonella sp identified in Stool by Organism specific culture

104

0.86

0.06

1.6

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

296

1.05

0.06

1.2

1.4

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

131

0.91

0.05

13.8

12.5

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

110

1.09

0.05

9.8

9.3

1.5

1.6

0.18

105

(3001122) Ferritin [Mass/volume] in Serum or Plasma

935

0.98

0.04

3.1

2.7

299.4

145.6

ug/l

0.94

855

(3019060) Gas panel - Arterial blood

170

1.06

0.04

10.5

7.0

—

(3003396) Base excess in Arterial blood by calculation

280

1.04

0.03

9.0

8.6

3.1

1.2

mmol/l

1.58

221

(3042936) Bacteria identified in Isolate by Culture

350

0.97

0.03

2.4

2.1

—

(3006504) Eosinophils/100 leukocytes in Blood

105

1062

0.98

0.03

7.4

5.9

2.6

2.9

0.68

100

997

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

127

0.94

0.01

2.4

—

(4010399)

164

1.04

0.00

1.4

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

122

0.98

0.00

1.3

1.8

1.5

g/l

0.53

110

(3005322) IgE [Units/volume] in Serum or Plasma

119

1.01

0.00

1.1

1.2

821.1

172.5

u/ml

0.93

106

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

141

0.99

0.00

2.4

1.7

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

281

1.00

0.00

2.0

3.2

5.1

8.7

umol/l

2.31

251

(3013707) Erythrocyte sedimentation rate by Westergren method

168

1679

1.00

0.00

5.0

4.0

13.5

13.2

mm/h

0.09

153

1526

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

744

0.99

0.00

3.0

3.2

1841.5

1499.0

ng/l

0.23

634

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

276

1.02

0.00

2.1

2.0

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

0.0

12.2

—

(3001964) Herpes simplex virus Ag [Presence] in Specimen

0.00

0.0

1.4

—

(40760109) Toxoplasma gondii IgG Ab avidity [Ratio] in Serum by Immunoassay

0.00

0.0

1.0

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

0.0

1.3

—

(3022907) Direct antiglobulin test.polyspecific reagent [Presence] on Red Blood Cells

0.00

0.0

1.0

—

(4198724)

0.00

0.0

1.2

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.94

0.00

1.4

1.5

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

1.02

0.00

1.8

—

(3014891) Appearance of Pleural fluid

0.00

0.0

1.2

—

(3052592) Norovirus Ag [Presence] in Stool

0.00

0.0

1.0

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

0.0

5.0

—

(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay

0.00

0.0

1.2

—

(3009876) Amylase isoenzyme 3 panel - Serum or Plasma

0.00

0.0

1.2

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.0

1.0

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.0

1.0

—

98.8

—

(40763634) TCRG gene rearrangements [Presence] in Bone marrow by Molecular genetics method

0.00

0.0

1.0

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.95

0.00

1.3

1.5

—

(3034037) Hematocrit [Volume Fraction] of Mixed venous blood

0.00

0.0

12.0

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

0.0

1.1

—

(3035509) Tobramycin [Mass/volume] in Serum or Plasma

0.00

0.0

3.2

—

1.1

—

(44806420)

0.00

0.0

2.3

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.92

0.00

1.7

1.2

—

(3028371) Actinomyces sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3000285) Sodium [Moles/volume] in Blood

0.00

0.0

1.0

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood

0.00

0.0

1.3

—

(3020650) Glucose [Presence] in Urine

0.00

0.0

1.1

—

(3021162) Amylase [Enzymatic activity/volume] in Specimen

0.00

0.0

2.2

—

12496.2

—

(3030313) Adrenal Ab [Titer] in Serum

0.00

0.0

1.0

—

(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

0.0

1.5

—

(3017962) TCRG gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.2

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.1

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.91

0.00

1.7

1.2

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.7

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(3028772) Osteocalcin [Mass/volume] in Serum or Plasma

0.00

0.0

2.4

—

(4094501)

0.84

0.00

1.2

1.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.92

0.00

1.7

1.2

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.00

0.00

1.3

1.5

—

(3034426) Prothrombin time (PT)

0.00

0.0

1.0

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

0.0

1.0

—

(3019174) dRVVT (LA screen)

0.00

0.0

1.2

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

0.0

12.0

—

(44806071)

0.00

0.0

1.2

—

(3044009) aPTT.lupus sensitive (LA screen)

0.00

0.0

1.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_SPINAMUSCOTH and mortality.

Females

Parameter	HR [95% CI]	p-value
G6_SPINAMUSCOTH	5.729 [4.42, 7.42]	< 0.001
Birth year	0.993 [0.98, 1.0]	0.129

During the follow-up period (1.1.1998 — 31.12.2019), 309 out of 670 females with G6_SPINAMUSCOTH died.

Males

Parameter	HR [95% CI]	p-value
G6_SPINAMUSCOTH	3.826 [3.06, 4.79]	< 0.001
Birth year	0.986 [0.98, 1.0]	0.004

During the follow-up period (1.1.1998 — 31.12.2019), 340 out of 805 males with G6_SPINAMUSCOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_SPINAMUSCOTH.

N-year risk	Females	Males
1	0.497%	0.723%
5	3.225%	3.906%
10	6.97%	10.02%
15	14.373%	18.355%
20	23.91%	30.396%

Relationships between endpoints

↥

Index endpoint: G6_SPINAMUSCOTH – Other and unspecified spinal muscular atrophies

GWS hits: 9

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other and unspecified spinal muscular atrophies

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints