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Melanoma in situ of trunk

CD2_INSITU_MELANOMA_TRUNK

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D03.5&
  • Cause of death: ICD-10 D03.5&

2 out of 7 registries used, show all original rules.

530

4. Check minimum number of events

None

530

5. Include endpoints

None

530

6. Filter based on genotype QC (FinnGen only)

509

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D03
Name in latin
Melanoma in situ trunci

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 509 201 308
Unadjusted period prevalence (%) 0.11 0.07 0.14
Median age at first event (years) 69.37 65.68 71.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
530
Matched controls
5300
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
82.2
307.7
405
201
D03.5
ICD-10 Finland
Melanoma in situ of trunk
+∞
307.7
530
*
D22.5
ICD-10 Finland
Melanocytic naevi of trunk
27.7
265.8
205
118
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
83.5
199.8
107
16
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
16.2
133.8
125
99
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
8.9
121.5
194
322
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
9.6
111.0
156
221
8720/2-C44.9
ICD-O-3
Melanoma in situ of skin, NOS
236.7
97.0
97
5
L57.0
ICD-10 Finland
Actinic keratosis
6.4
85.3
188
422
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
13.8
71.6
70
58
R23.8
ICD-10 Finland
Other and unspecified skin changes
5.0
70.6
220
655
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
9.8
67.1
84
100
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
11.4
65.2
72
72
8720/3-C44.5
ICD-O-3
Malignant melanoma, NOS, of skin of trunk
28.1
64.0
44
17
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.5
61.3
145
338
D22.7
ICD-10 Finland
Melanocytic naevi of lower limb, including hip
15.1
56.9
52
38
8720/3-C44.9
ICD-O-3
Malignant melanoma, NOS, of skin, NOS
19.4
53.9
43
24
TQW99
NOMESCO Finland
Other minor procedure on skin
6.4
48.7
90
165
QXE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in uspecified region
20.9
48.0
37
19
S18
ICPC
Laceration/cut
3.8
45.5
372
2020
C43.59
ICD-10 Finland
Malignant melanoma of the trunk other or unspecified histology
55.8
39.2
46
9
C43.50
ICD-10 Finland
Malignant melanoma of the torso without histology
68.3
38.7
44
7
S82
ICPC
Naevus/mole
4.1
38.6
131
396
XQ846
NOMESCO Finland
Digital dermatoscopy and registration of nevi
110.9
38.3
41
*
ZXC50
NOMESCO Finland
Cryotherapy
7.2
37.4
59
91
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
9.4
37.2
46
53
ZZR00
NOMESCO Finland
Flap of skin
9.1
37.0
47
56
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
4.5
36.0
101
264
C43
ICD-10 Finland
Malignant melanoma of skin
124.7
33.1
35
*
L82
ICD-10 Finland
Seborrhoeic keratosis
3.3
32.9
164
632
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
6.3
31.8
57
100
PJA12
NOMESCO Finland
Sentinel node biopsy
4.5
30.2
81
203
8720/2-C44.5
ICD-O-3
Melanoma in situ of skin of trunk
+∞
29.4
28
*
S77
ICPC
Malignant neoplasm of skin
10.9
29.2
32
31
C43.51
ICD-10 Finland
Malignant melanoma of the trunk originating in lentigo maligna
105.8
27.9
30
*
C43.5
ICD-10 Finland
Malignant neoplasm: Malignant melanoma of trunk
50.1
27.8
33
7
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
6.7
27.4
45
72
D22
ICD-10 Finland
Melanocytic naevi
6.0
26.7
49
88
C44.61
ICD-10 Finland
Basocellular carcinoma of the skin of the upper extremity including the shoulder
10.5
24.9
28
28
D06BB10
ATC
imiquimod; topical
4.6
24.2
61
145
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
8.5
22.8
30
37
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
7.5
21.8
32
45
D04.5
ICD-10 Finland
Carcinoma in situ: Skin of trunk
16.7
20.8
33
21
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
5.7
20.7
40
75
SPAT1153
SPAT
Removal of sutures
2.4
20.7
238
1353
XQ845
NOMESCO Finland
Dermatoscopy
7.3
20.6
31
45
D22.6
ICD-10 Finland
Melanocytic naevi of upper limb, including shoulder
15.4
19.6
32
22
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
3.5
19.1
70
218
TQW40, ,
SPAT
3.5
19.1
70
218
XQ848
NOMESCO Finland
Dermatological photography
5.2
18.6
39
79
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
5.9
17.5
32
57
C43.62
ICD-10 Finland
Malignant melanoma of upper extremity including shoulder: 'superficial spreading' type
25.1
17.5
24
10
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
7.1
17.1
26
38
8743/3-C44.9
ICD-O-3
Low cumulative sun damage melanoma of skin, NOS
62.0
15.9
18
*
8742/2-C44.9
ICD-O-3
Lentigo maligna of skin, NOS
32.8
14.9
19
6
S29
ICPC
Skin symptom/complaint other
2.3
14.5
133
669
D04.7
ICD-10 Finland
Carcinoma in situ: Skin of lower limb, including hip
17.6
14.4
22
13
D03.6
ICD-10 Finland
Melanoma in situ of upper limb, including shoulder
43.8
14.2
17
*
8743/3-C44.5
ICD-O-3
Low cumulative sun damage melanoma of skin of trunk
+∞
13.6
13
*
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
5.3
13.3
27
53
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
5.7
13.2
25
46
C43.72
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip: 'superficial spreading' type
29.2
13.0
17
6
ZXC20
NOMESCO Finland
Use of chemical agents
4.9
13.0
29
62
D03.7
ICD-10 Finland
Melanoma in situ of lower limb, including hip
51.3
12.9
15
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
5.5
12.9
25
47
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
10.9
12.4
23
22
Z2221
NOMESCO Finland
Medical doctor
2.0
11.8
165
969
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
5.4
11.6
23
44
D03.31
ICD-10 Finland
Melanoma in situ in another or unspecified part of the face
23.5
11.6
16
7
D04.6
ICD-10 Finland
Carcinoma in situ: Skin of upper limb, including shoulder
12.2
11.4
20
17
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
3.9
11.0
33
89
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
3.8
10.8
34
95
ZQZ00
NOMESCO Finland
Treatment of several skin areas
12.4
10.4
18
15
C43.69
ICD-10 Finland
Malignant melanoma of the upper extremity including shoulder other or unspecified histology
40.9
10.0
12
*
A98
ICPC
Health maint/preventive medicine
4.8
9.9
515
4652
C44.52
ICD-10 Finland
Spinocellular carcinoma of the skin on the torso
12.6
9.4
16
13
8742/2-C44.5
ICD-O-3
Lentigo maligna of skin of trunk
+∞
9.4
9
*
ZXE00
NOMESCO Finland
One hour or less
1.8
9.3
217
1483
C43.53
ICD-10 Finland
Malignant melanoma of the torso nodular
19.0
9.0
13
7
C44.22
ICD-10 Finland
Spinocellular carcinoma of the skin of the outer ear and the outer ear canal
24.5
8.9
12
5
S54
ICPC
Skin, Repair/fix-suture/cast/prosth device
3.7
8.7
27
75
C43.70
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip without histology
16.6
8.6
13
8
C43.31
ICD-10 Finland
Malignant melanoma of another or unspecified part of the face originating in lentigo maligna
28.0
8.5
11
*
QBE10, ,
SPAT
20.4
8.5
12
6
C43.71
ICD-10 Finland
Malignant melanoma of the lower extremity including the hip originating in lentigo maligna
+∞
8.4
8
*
L81.4
ICD-10 Finland
Other melanin hyperpigmentation
10.3
8.1
15
15
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
8.0
358
2889
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.7
7.8
44
175
ZXE10
NOMESCO Finland
More than one and less than three hours
1.7
7.7
203
1416
XKD00
NOMESCO Finland
Uroflowmetry
1.8
7.6
126
769
J01DB01
ATC
cefalexin; oral
1.9
7.5
427
3652
8742/3-C44.9
ICD-O-3
Lentigo maligna melanoma of skin, NOS
81.2
7.4
8
*
S21
ICPC
Skin texture symptom/complaint
2.0
7.3
88
484
TQW80
NOMESCO Finland
Local dermatologic skincare
3.8
7.3
22
60
N02BE01
ATC
paracetamol; systemic, rectal
2.2
7.2
477
4252
C43.99
ICD-10 Finland
Unspecified localization of malignant melanoma of the skin other or unspecified histology
30.5
7.2
9
*
8720/3-C44.6
ICD-O-3
Malignant melanoma, NOS, of skin of upper limb and shoulder
20.3
7.2
10
5
180
Kela drug reimbursment
Interferon alfa
14.0
6.9
11
8
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
14.0
6.9
11
8
C44.91
ICD-10 Finland
Unspecified localization of basocellular carcinoma of the skin
14.0
6.9
11
8
E0000UV, ,
ATC
1.6
6.9
212
1530
F16
ICPC
Eyelid symptom/complaint
3.0
6.7
30
105
R05
ICD-10 Finland
Cough
1.8
6.6
113
694
QBE20
NOMESCO Finland
Excision and repair of scar or web of skin of trunk
12.4
6.6
11
9
D04.2
ICD-10 Finland
Carcinoma in situ: Skin of ear and external auricular canal
10.2
6.6
12
12
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.3
6.5
51
237
Z31.5
ICD-10 Finland
Genetic counselling
3.1
6.4
26
86
QDE99
NOMESCO Finland
Other excision or repair of lesion of skin of lower limb
14.5
6.4
10
7
L72.1
ICD-10 Finland
Trichilemmal cyst
2.4
6.4
42
180
D03.9
ICD-10 Finland
Melanoma in situ, unspecified
18.3
6.3
9
5
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.4
6.2
22
67
R5110, ,
SPAT
2.4
6.2
42
183
C44.62
ICD-10 Finland
Spinocellular carcinoma of the skin of the upper extremity including the shoulder
12.7
6.1
10
8
QBE00
NOMESCO Finland
Excision of loose skin or fold of skin from trunk
12.7
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
280
592
8.91
143.55
2.1
1.3
—
—
—
0
0
427
1798
8.07
97.44
4.4
2.2
—
—
—
0
0
138
429
4.00
39.15
1.4
1.4
—
—
—
0
0
80
196
4.63
30.75
1.4
1.3
—
—
—
0
0
514
4610
4.81
10.56
14.1
11.3
25.35
25.46
u/l
0.06
488
4439
271
1947
1.80
9.99
12.7
10.3
0.00
0.00
e9/l
0.72
213
1609
493
4352
2.90
9.60
18.4
16.4
21.66
26.49
mg/l
2.97
405
3521
194
1277
1.82
9.44
3.6
3.2
0.76
0.78
ug/l
0.12
137
872
505
4565
3.25
8.43
22.1
19.7
3.95
4.00
mmol/l
4.94
490
4443
518
4758
4.92
8.39
28.1
24.3
241.32
239.82
e9/l
0.21
507
4630
518
4759
4.91
8.37
28.0
24.4
40.39
39.95
%
1.05
503
4417
518
4759
4.91
8.37
27.9
24.1
30.44
30.48
pg
0.20
511
4682
504
4554
3.18
8.36
21.7
19.6
139.82
139.65
mmol/l
0.84
490
4433
518
4760
4.90
8.34
28.0
24.2
91.69
91.61
fl
0.14
511
4684
518
4760
4.90
8.34
28.1
24.3
6.69
6.86
e9/l
1.14
505
4616
518
4760
4.90
8.34
28.1
24.3
4.47
4.46
e12/l
0.25
505
4616
518
4761
4.89
8.32
28.3
24.4
134.77
134.86
g/l
0.05
511
4681
419
3537
1.88
8.03
10.2
8.0
78.60
80.15
u/l
0.20
393
3320
455
3962
2.05
7.74
5.5
4.5
1.96
2.28
mu/l
0.50
403
3564
489
4400
2.44
7.31
5.9
5.3
2.62
2.62
mmol/l
0.02
428
3997
496
4497
2.60
7.18
16.4
15.6
—
—
—
0
0
163
1094
1.71
7.04
7.5
7.3
—
—
—
0
0
265
2016
1.63
7.02
8.0
5.8
0.66
0.64
%
0.33
238
1885
220
1606
1.63
6.83
4.8
3.7
2.34
2.35
mmol/l
0.15
188
1403
236
1758
1.62
6.72
2.2
2.2
80.24
77.53
nmol/l
0.82
211
1553
270
2080
1.61
6.67
7.8
5.8
2.86
2.90
%
0.09
243
1946
362
2999
1.65
6.61
4.6
4.6
4550.30
2700.14
e6/l
—
10
50
208
1507
1.63
6.60
2.7
2.5
—
—
—
0
0
291
2289
1.60
6.54
7.6
5.9
0.19
0.20
e9/l
0.15
239
2016
270
2088
1.60
6.51
8.0
6.2
9.06
8.81
%
0.63
245
1954
270
2092
1.59
6.43
7.7
6.1
—
—
—
0
0
270
2093
1.59
6.41
7.6
5.8
58.46
58.09
%
0.20
244
1969
478
4305
2.12
6.39
5.3
4.7
4.50
4.48
mmol/l
0.10
421
3944
388
3285
1.68
6.37
4.9
4.2
12.50
13.27
mm/h
0.41
345
3013
272
2119
1.58
6.27
7.9
6.0
26.56
26.44
%
0.07
247
1987
227
1696
1.59
6.26
4.9
3.9
86.00
72.73
e6/l
0.16
168
1229
205
1496
1.60
6.24
4.1
3.4
21.05
121.02
e6/l
1.55
161
1155
474
4264
2.06
6.23
5.3
4.7
1.44
1.43
mmol/l
0.21
418
3868
259
2012
1.56
5.94
2.3
2.1
92.22
94.29
pmol/l
0.32
146
1079
375
3178
1.62
5.82
4.5
3.7
15.05
14.94
pmol/l
0.37
323
2833
280
2221
1.55
5.80
7.5
5.7
0.60
0.61
e9/l
0.12
228
1916
280
2227
1.55
5.69
7.5
5.7
0.04
0.04
e9/l
0.23
228
1931
314
2566
1.55
5.60
11.4
9.5
3.87
4.26
e9/l
3.04
261
2266
460
4132
1.86
5.55
4.8
4.2
1.29
1.28
mmol/l
0.08
403
3730
283
2264
1.54
5.54
7.5
5.8
1.78
1.94
e9/l
1.18
234
2009
150
1041
1.61
5.50
3.1
2.7
3.48
4.51
e6/l
1.04
130
936
165
1174
1.59
5.44
4.5
4.1
85.61
86.26
%
0.12
160
1154
459
4128
1.84
5.41
6.8
6.4
39.86
40.76
mmol/mol
1.41
408
3809
272
2169
1.52
5.33
6.0
6.3
1.21
1.21
mmol/l
0.72
237
1967
363
3084
1.56
5.28
4.4
4.4
—
—
—
0
0
275
2202
1.52
5.26
6.2
5.4
7.48
2.86
ug/l
0.65
235
1942
473
4305
1.92
5.20
5.7
5.0
6.02
6.08
mmol/l
0.49
411
3889
420
3698
1.65
5.20
24.8
19.7
15.73
15.27
%
0.69
411
3649
303
2484
1.51
5.13
8.4
6.7
11.12
12.13
umol/l
1.25
281
2370
289
2360
1.49
4.89
6.3
7.2
1.21
1.21
mmol/l
0.24
231
2012
136
950
1.58
4.77
4.6
3.2
2.46
2.45
mmol/l
0.26
120
834
141
1000
1.56
4.62
3.5
3.1
601.94
559.50
mosm/kgh2o
1.59
115
853
183
1380
1.50
4.49
4.0
3.3
0.63
0.52
e6/l
0.17
141
1041
175
1311
1.50
4.42
4.0
3.2
—
—
—
0
0
289
2397
1.45
4.29
19.5
17.0
1.25
1.32
inr
0.73
94
679
168
1257
1.49
4.24
3.2
2.9
6718.73
7639.39
umol/l
0.07
144
1083
71
434
1.73
4.17
3.4
3.1
65.71
66.36
g/l
0.25
64
394
63
372
1.79
4.16
4.1
3.7
—
—
—
0
0
41
210
2.03
4.14
1.3
1.2
76.18
163.26
iu/ml
1.30
11
87
257
2095
1.44
4.13
6.2
5.0
35.52
35.02
g/l
0.84
239
1956
88
573
1.64
4.09
1.4
1.4
—
—
—
0
0
14
36
3.97
4.02
1.4
1.8
—
—
—
0
0
30
140
2.21
3.84
2.3
3.1
—
—
—
0
0
115
813
1.53
3.76
3.7
3.1
0.97
1.70
e6/l
1.36
71
454
161
1221
1.46
3.73
2.3
2.1
2.72
3.15
mg/l
1.08
128
1053
364
3204
1.43
3.60
4.3
4.3
—
—
—
0
0
181
1412
1.43
3.58
4.6
4.3
7.39
7.40
ph
1.45
41
269
152
1149
1.45
3.56
2.6
2.5
—
—
—
0
0
21
88
2.44
3.43
1.3
1.5
4.42
6.83
iu/l
—
5
26
178
1393
1.42
3.43
3.5
3.2
—
—
—
0
0
62
386
1.69
3.42
4.9
4.1
1.22
1.22
mmol/l
0.15
50
341
19
79
2.46
3.17
1.2
1.2
7.85
9.62
u/l
0.39
14
64
13
41
3.22
3.07
1.1
1.2
—
—
—
0
0
32
168
1.96
3.07
2.0
3.0
37.47
37.52
g/l
0.02
27
147
184
1473
1.38
3.04
2.2
2.1
173.86
265.71
u/l
0.90
169
1379
257
2170
1.36
3.04
2.9
2.7
—
—
—
0
0
16
65
2.51
2.81
1.2
1.4
—
—
—
0
0
184
1491
1.36
2.78
3.7
4.3
—
—
—
0
0
318
2796
1.34
2.78
5.0
5.0
6.58
6.83
mmol/l
1.55
303
2634
59
384
1.60
2.76
2.1
2.1
13.94
12.86
nmol/l
0.30
52
340
7
200
0.34
2.72
1.1
3.8
3.00
1.43
mmol/l
—
7
195
316
2782
1.34
2.70
3.0
3.3
40.12
54.70
u/l
5.39
283
2584
34
191
1.83
2.69
2.0
3.0
10.91
10.58
g/l
0.14
29
169
158
1257
1.37
2.67
1.6
1.6
21.41
20.04
nmol/l
0.55
123
1062
8
208
0.38
2.46
1.8
4.4
—
—
—
0
0
125
972
1.37
2.41
1.7
1.7
1125.44
1172.51
nmol/l
0.21
80
744
85
621
1.44
2.34
3.9
2.4
1.78
1.79
%
0.03
75
567
72
511
1.47
2.30
1.5
1.3
—
—
—
0
0
11
40
2.79
2.28
2.3
1.8
8.52
10.49
%
0.75
11
40
17
80
2.16
2.21
1.2
1.4
—
—
—
0
0
53
359
1.53
2.13
3.8
2.8
—
—
—
0
0
14
62
2.29
2.09
1.1
1.3
—
—
—
0
0
84
628
1.40
2.05
1.4
1.2
—
—
—
0
0
8
26
3.11
2.02
1.0
1.2
1.81
1.80
mmol/l
—
8
26
64
458
1.45
1.98
1.5
1.6
—
—
—
0
0
18
91
2.01
1.97
1.3
1.3
—
—
—
0
0
7
21
3.36
1.97
1.3
1.6
—
—
—
0
0
214
1842
1.27
1.95
3.0
2.8
133.48
158.58
ug/l
1.08
187
1685
42
276
1.57
1.94
8.4
10.1
24.28
24.54
mmol/l
0.28
42
269
146
1198
1.30
1.93
1.6
1.6
1.31
1.34
mmol/l
0.17
107
981
100
777
1.35
1.93
3.1
3.3
0.81
0.82
mmol/l
0.07
89
732
61
435
1.45
1.93
2.3
2.2
92.26
131.40
ug/g
0.80
43
347
140
1145
1.30
1.90
1.6
1.3
—
—
—
0
0
94
726
1.36
1.89
1.8
2.0
—
—
—
0
0
120
965
1.31
1.84
4.2
3.9
100.63
311.37
ng/l
1.87
98
813
75
564
1.38
1.78
4.4
4.5
4.16
32.78
ug/l
1.30
64
478
14
67
2.12
1.77
1.6
1.4
3123.00
1828.24
e6/l
—
8
42
58
417
1.44
1.77
1.5
1.6
—
—
—
0
0
12
54
2.25
1.75
2.1
2.5
—
—
—
0
0
13
61
2.16
1.73
1.6
1.4
125066.67
27953.26
e6/l
—
6
34
11
48
2.32
1.71
2.0
2.7
—
—
—
0
0
28
172
1.66
1.71
5.8
4.3
39.81
97.26
mg/l
0.89
21
138
28
172
1.66
1.71
5.8
4.3
27.00
36.49
mg/l
1.28
21
141
56
403
1.44
1.70
5.3
1.9
437.08
379.89
nmol/l
0.34
48
374
21
119
1.80
1.68
1.4
1.7
5481.27
12907.72
e6/l
1.30
11
93
38
253
1.54
1.68
1.2
1.5
—
—
—
0
0
74
956
0.74
1.65
3.6
4.4
1.02
1.02
kg/l
—
10
136
14
262
0.52
1.64
5.3
3.8
24.27
25.18
mmol/l
1.06
14
256
63
468
1.39
1.61
4.0
2.5
63.52
68.84
e9/l
0.48
42
373
169
1442
1.25
1.61
3.1
3.5
34.45
33.20
u/l
0.10
159
1376
72
552
1.35
1.53
1.7
1.7
—
—
—
0
0
22
354
0.61
1.52
2.7
4.5
—
—
—
0
0
7
27
2.61
1.52
1.1
1.4
—
—
—
0
0
11
51
2.18
1.51
1.6
1.4
—
—
—
0
0
14
74
1.92
1.40
3.9
2.8
4.19
4.88
e9/l
0.87
14
74
68
526
1.34
1.38
1.5
1.7
—
—
—
0
0
5
17
2.96
1.36
1.6
1.1
5.94
7.56
mmol/l
—
5
17
136
1154
1.24
1.34
3.3
3.5
—
—
—
0
0
20
121
1.68
1.32
6.9
4.7
—
—
—
0
0
62
477
1.34
1.31
4.0
4.6
—
—
—
0
0
14
76
1.86
1.31
4.3
3.2
60.00
60.34
%
0.05
14
76
14
77
1.84
1.26
3.9
1.7
32.93
32.74
pg
0.07
14
77
21
131
1.63
1.25
1.5
1.5
277.77
283.32
ug/g
0.05
13
80
12
63
1.93
1.23
1.0
1.1
—
—
—
0
0
6
26
2.32
1.19
1.0
1.1
—
—
—
0
0
122
1037
1.23
1.18
1.6
1.8
422.78
6745986.20
pmol/l
0.50
91
845
237
2147
1.19
1.17
3.4
3.9
0.00
0.00
estimate
-0.00
64
437
18
111
1.64
1.13
2.3
2.8
—
—
—
0
0
7
30
2.35
1.12
1.4
1.8
34.49
34.44
%
—
7
30
12
66
1.84
1.09
1.8
1.7
—
—
—
0
0
5
21
2.39
1.09
2.0
2.5
—
—
—
0
0
49
376
1.33
1.08
3.5
4.1
105.75
90.71
ng/l
0.44
39
334
11
60
1.85
1.03
1.5
1.5
—
—
—
0
0
31
423
0.72
1.01
2.7
3.4
—
—
—
0
0
93
782
1.23
1.01
2.0
1.4
2.17
2.74
g/l
2.40
58
461
19
124
1.55
0.98
2.1
1.7
—
—
—
0
0
9
51
1.78
0.95
1.3
1.2
—
—
—
0
0
8
146
0.54
0.94
3.9
12.6
—
—
—
0
0
6
27
2.24
0.93
2.2
2.2
—
—
—
0
0
6
28
2.16
0.91
1.7
1.5
0.94
0.96
g/l
—
6
28
233
2141
1.16
0.91
4.6
5.3
0.00
0.00
estimate
-0.00
61
403
22
152
1.47
0.89
1.0
1.1
—
—
—
0
0
8
42
1.92
0.89
1.4
1.1
—
—
—
0
0
8
44
1.83
0.86
1.1
1.3
—
—
—
0
0
235
2171
1.15
0.84
3.5
3.9
0.05
0.00
estimate
0.49
59
390
54
438
1.26
0.82
1.5
1.5
—
—
—
0
0
33
251
1.34
0.80
1.9
1.8
1.46
1.52
g/l
0.15
28
219
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
6
33
1.83
0.79
1.2
1.1
—
—
—
0
0
8
48
1.68
0.79
1.6
2.0
—
—
—
0
0
53
433
1.25
0.77
3.0
2.5
33.60
32.89
u/l
0.06
48
372
16
107
1.51
0.77
2.2
2.3
15.89
15.75
%
—
9
49
6
34
1.77
0.76
1.5
2.8
—
—
—
0
0
15
99
1.53
0.76
4.5
3.8
—
—
—
0
0
14
91
1.55
0.76
2.4
2.4
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
8.00
—
0
7
174
1586
1.14
0.74
3.3
3.2
1887.21
1513.22
ng/l
0.38
147
1382
133
1190
1.16
0.74
3.5
4.1
0.00
0.01
estimate
0.50
60
386
7
38
1.85
0.73
1.0
1.1
—
—
—
0
0
15
218
0.68
0.73
5.1
4.3
24.45
25.02
mmol/l
0.37
15
205
12
76
1.59
0.72
1.4
1.4
56.40
266.38
miu/ml
—
5
29
7
40
1.76
0.71
1.1
1.3
—
—
—
0
0
33
257
1.30
0.70
2.5
3.0
—
—
—
0
0
13
85
1.54
0.69
1.8
1.8
205.38
217.67
pmol/l
0.28
13
79
5
30
1.67
0.61
2.0
2.6
—
—
—
0
0
51
428
1.21
0.60
8.2
8.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.6
—
57.38
—
0
13
0
20
0.00
0.60
0.0
1.5
—
—
—
0
0
11
72
1.54
0.59
1.8
1.7
0.81
0.88
g/l
—
6
58
0
22
0.00
0.59
0.0
1.2
—
176.58
—
0
22
0
23
0.00
0.58
0.0
1.7
—
1.03
—
0
16
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
63
542
1.18
0.58
1.4
1.3
508.57
452.54
titre
0.11
14
118
43
357
1.22
0.57
4.0
4.3
0.15
0.12
%
0.09
13
128
30
239
1.27
0.56
2.6
2.5
—
—
—
0
0
10
148
0.67
0.56
3.8
4.9
—
—
—
0
0
12
82
1.47
0.54
1.2
1.2
—
—
—
0
0
164
1518
1.12
0.54
3.9
3.2
7.53
7.69
mmol/l
0.19
123
1247
29
234
1.25
0.50
3.3
4.0
24.21
24.19
mmol/l
0.01
29
229
40
335
1.21
0.50
4.1
4.3
0.00
0.14
%
—
10
106
10
67
1.50
0.50
1.4
1.4
—
—
—
0
0
18
136
1.33
0.49
1.4
1.2
—
—
—
0
0
160
1487
1.11
0.49
4.0
3.3
482.43
370.54
mg/l
0.10
105
985
35
290
1.22
0.49
6.8
9.9
—
—
—
0
0
23
182
1.28
0.47
1.4
1.9
—
—
—
0
0
7
48
1.46
0.47
1.7
1.0
—
—
—
0
0
7
49
1.43
0.46
1.7
1.2
—
—
—
0
0
8
121
0.66
0.46
1.8
1.9
11.56
13.28
mg/l
—
8
110
182
1709
1.10
0.46
3.0
3.7
5.79
5.81
ph
0.04
14
101
11
78
1.42
0.43
3.7
3.2
—
—
—
0
0
151
1412
1.10
0.41
3.1
3.2
—
—
—
0
0
5
33
1.52
0.41
1.2
1.3
—
—
—
0
0
93
848
1.12
0.41
1.3
1.2
1.62
1.66
u/ml
0.01
30
216
0
16
0.00
0.41
0.0
10.1
—
0.65
—
0
16
45
390
1.17
0.41
1.5
1.4
—
—
—
0
0
106
974
1.11
0.41
2.5
1.7
1.63
1.37
mg/l
0.29
75
761
76
685
1.13
0.41
1.3
1.3
28.81
45.04
iu/ml
0.62
24
222
81
734
1.12
0.40
2.7
2.6
2.32
2.28
g/l
0.23
76
679
0
18
0.00
0.40
0.0
1.1
—
332.60
—
0
10
13
97
1.35
0.40
1.3
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
21
257
0.81
0.38
4.1
3.9
—
—
—
0
0
8
112
0.71
0.37
1.0
1.1
—
—
—
0
0
14
107
1.32
0.37
3.9
4.1
42.29
26.93
mg/l
—
7
67
9
69
1.31
0.37
6.0
5.3
8.40
11.22
mg/l
—
9
63
5
37
1.35
0.37
3.6
3.8
6.79
44.03
mg/l
—
5
32
9
121
0.74
0.35
1.0
1.1
—
—
—
0
0
10
134
0.74
0.35
1.0
1.2
—
—
—
0
0
72
654
1.12
0.35
5.8
6.1
1.04
1.02
mmol/l
0.23
65
600
22
181
1.22
0.35
1.2
1.1
—
30.17
—
0
6
22
181
1.22
0.35
3.2
3.3
0.54
0.21
g/l
—
9
76
27
228
1.19
0.34
1.3
1.3
—
—
—
0
0
29
247
1.18
0.33
1.2
1.3
—
—
—
0
0
21
252
0.83
0.32
3.2
4.0
—
—
—
0
0
153
1449
1.08
0.32
4.8
4.4
—
—
—
0
0
34
296
1.16
0.31
2.9
2.7
4.05
7.36
e9/l
0.89
24
234
38
336
1.14
0.29
1.3
1.5
—
—
—
0
0
39
346
1.14
0.28
3.7
4.1
0.22
0.50
%
—
9
131
165
1574
1.07
0.28
5.3
3.9
9.44
9.45
mg/mmol
0.00
104
1014
56
613
0.90
0.27
7.1
7.4
0.38
1.17
mmol/l
1.00
45
485
43
386
1.12
0.27
4.0
4.2
0.65
1.02
%
0.53
13
157
14
114
1.23
0.25
1.9
2.3
—
—
—
0
0
12
96
1.26
0.24
1.8
1.6
—
—
—
0
0
10
79
1.27
0.22
2.1
2.9
—
—
—
0
0
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
76
712
1.08
0.22
2.8
2.6
22.37
22.37
%
0.00
70
602
16
188
0.85
0.21
1.6
1.4
—
—
—
0
0
5
42
1.19
0.21
1.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
5.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
28
249
1.13
0.21
2.1
2.7
0.63
0.66
%
0.24
28
249
5
43
1.16
0.21
1.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
48
1.25
0.20
1.2
1.3
—
—
—
0
0
31
343
0.90
0.19
3.6
3.7
5.20
5.13
kpa
0.16
31
330
10
81
1.24
0.19
2.0
1.4
—
—
—
0
0
7
60
1.17
0.18
2.6
2.8
—
—
—
0
0
198
1925
1.05
0.17
3.4
4.0
37.34
41.57
ng/l
0.20
146
1472
59
554
1.07
0.17
3.2
2.9
7.39
9.11
umol/l
0.33
53
498
5
69
0.72
0.17
1.0
1.1
—
45.53
—
0
15
97
1013
0.95
0.16
3.3
3.9
—
—
—
0
0
13
111
1.18
0.16
1.8
1.2
—
61.43
—
0
7
8
73
1.10
0.15
1.9
1.9
88.34
89.74
%
—
8
73
6
76
0.79
0.15
3.7
4.2
0.42
1.36
%
—
6
70
6
76
0.79
0.15
1.2
1.1
—
—
—
0
0
6
79
0.76
0.15
1.5
1.1
306.85
43.42
u/l
—
6
69
6
79
0.76
0.15
2.7
3.2
—
—
—
0
0
6
80
0.75
0.15
2.7
3.1
106.17
105.01
mmol/l
—
6
80
6
80
0.75
0.15
2.7
3.1
3.92
4.08
mmol/l
—
6
80
31
337
0.91
0.15
3.6
3.7
7.38
7.40
ph
—
6
33
10
84
1.19
0.14
7.5
1.9
—
—
—
0
0
12
103
1.17
0.14
2.3
1.9
131.75
127.13
g/l
0.23
12
74
13
113
1.15
0.13
5.4
4.7
3.43
2.14
mmol/l
—
6
75
10
85
1.18
0.12
1.4
1.3
—
—
—
0
0
46
484
0.95
0.10
1.5
2.5
8.37
7.48
ug/l
0.14
37
433
24
259
0.92
0.10
1.5
1.3
—
—
—
0
0
5
46
1.09
0.09
2.0
2.5
—
—
—
0
0
68
656
1.04
0.09
1.3
1.3
2.68
14.71
u/ml
3.02
22
240
6
55
1.09
0.09
1.2
1.1
—
—
—
0
0
15
136
1.11
0.08
1.7
1.6
—
—
—
0
0
5
60
0.83
0.08
2.4
4.3
—
—
—
0
0
10
88
1.14
0.08
1.1
1.2
—
—
—
0
0
7
64
1.09
0.08
1.1
1.1
1.65
1.53
g/l
—
7
58
148
1503
0.98
0.06
3.2
2.5
58.47
113.06
u/l
0.52
130
1397
82
801
1.03
0.06
2.9
2.6
12.39
12.74
umol/l
0.16
76
749
47
455
1.04
0.05
2.8
3.1
160.40
201.72
ng/l
0.50
42
413
10
107
0.93
0.02
4.9
3.4
84.93
382.60
u/ml
—
10
101
10
96
1.04
0.00
1.3
1.7
—
—
—
0
0
13
126
1.03
0.00
1.5
1.5
—
—
—
0
0
23
233
0.99
0.00
2.3
1.9
3.79
2.75
ug/l
0.16
18
206
11
108
1.02
0.00
1.3
1.3
—
—
—
0
0
22
222
0.99
0.00
1.8
1.3
—
—
—
0
0
28
278
1.01
0.00
1.2
1.2
—
—
—
0
0
31
312
0.99
0.00
2.6
3.0
—
—
—
0
0
20
201
0.99
0.00
1.6
1.5
—
—
—
0
0
0
9
0.00
0.00
0.0
5.8
—
—
—
0
0
5
54
0.93
0.00
1.4
1.3
—
0.54
—
0
5
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
5
54
0.93
0.00
1.4
1.3
0.66
0.53
nmol/l
—
5
47
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
3.3
3.2
2.63
6.62
nmol/l
—
6
61
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
0.92
—
0
6
6
69
0.87
-0.00
1.2
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
1.90
—
0
6
5
52
0.96
-0.00
1.4
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
36.13
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
17.97
—
0
7
9
95
0.95
-0.00
2.7
2.9
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: CD2_INSITU_MELANOMA_TRUNK – Melanoma in situ of trunk

GWS hits: 2

This endpoint is excluded from FinRegistry analyses (omitted endpoint).