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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_BASEOFTONGUE_EXALLC for full statistics.

Malignant neoplasm of base of tongue

C3_BASEOFTONGUE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C01&
  • Cause of death: ICD-9 1410A
  • Cause of death: ICD-8 1410
  • Cancer registry: Topography ICD-O-3 C01
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

188

4. Check minimum number of events

None

188

5. Include endpoints

None

188

6. Filter based on genotype QC (FinnGen only)

188

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF9

Similar endpoints

List of similar endpoints to Malignant neoplasm of base of tongue based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

None

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 188 46 142
Unadjusted period prevalence (%) 0.05 0.02 0.06
Median age at first event (years) 62.40 63.92 61.90

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
180
Matched controls
1799
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C01
ICD-10 Finland
Malignant neoplasm of base of tongue
8974.8
196.5
152
*
8070/3-C01.9
ICD-O-3
Squamous cell carcinoma, NOS, of base of tongue, NOS
+∞
160.3
129
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
498.7
126.9
113
6
130
Kela drug reimbursment
Malignant tumour
65.1
111.3
136
81
JDB10
NOMESCO Finland
Percutaneous gastrostomy
289.8
102.5
96
7
UJC01
NOMESCO Finland
Scopy of lower throat
177.4
74.7
74
7
WF002
NOMESCO Finland
Radical radiotherapy
31.0
64.8
90
56
A03FA01
ATC
metoclopramide; systemic, rectal
15.2
56.5
115
187
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
45.4
53.2
65
22
N02AA05
ATC
oxycodone; systemic
14.6
51.6
102
148
EJA10
NOMESCO Finland
Biopsy of tongue or floor of mouth
49.2
50.1
60
18
C77.0
ICD-10 Finland
Secondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
112.0
40.9
43
5
R4190
NOMESCO Finland
Nutritional therapy
43.0
39.1
48
15
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
22.4
35.2
52
32
EJB20
NOMESCO Finland
Excision of lesion of base of tongue
+∞
34.5
32
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
143.8
34.0
35
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
68.2
33.8
38
7
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
76.9
33.5
37
6
GDA98
NOMESCO Finland
Other bronchoscopic incision, excision of lesion or repair of lung
86.2
32.2
35
5
EP1AE
NOMESCO Finland
Neck ultrasound examination
15.8
30.7
52
45
A04AA01
ATC
ondansetron; systemic, rectal
16.4
29.0
48
39
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
6.2
28.7
116
408
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
19.8
28.2
43
28
GBB00
NOMESCO Finland
Tracheostomy
44.4
27.3
33
9
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
16.3
26.7
44
35
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
157.8
26.4
27
*
ENA10
NOMESCO Finland
Biopsy of pharynx
+∞
25.6
24
*
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
44.6
24.8
30
8
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
24.5
23
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
19.9
24.5
37
23
ZX095
NOMESCO Finland
Combined chemoradiotherapy
100.8
24.4
26
*
H02AB02
ATC
dexamethasone; systemic
8.6
23.7
56
90
A07AA02
ATC
nystatin; oral
13.0
23.2
42
41
C02.11
ICD-10 Finland
Malignant neoplasm of border of tongue
249.0
22.1
22
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
4.8
22.0
117
500
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
9.9
21.9
46
60
ZX090
NOMESCO Finland
Other technic of radiotherapy
21.3
21.8
32
18
UDQ12
NOMESCO Finland
Flexible laryngoscopy
10.2
21.7
45
57
EBA15
NOMESCO Finland
Extraction of large number of teeth
11.9
21.2
40
42
SAA03
NOMESCO Finland
Extended examination of mouth
4.7
21.1
108
437
XX3DW
NOMESCO Finland
Time consuming IT work
7.4
20.5
53
96
JCW98
NOMESCO Finland
Other transluminal endoscopic procedure on oesophagus
223.6
20.0
20
*
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
52.4
19.7
23
5
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
31.9
19.3
25
9
A04AD12
ATC
aprepitant; systemic
31.9
19.3
25
9
A04AA02
ATC
granisetron; systemic, transdermal
9.1
19.2
42
58
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
43.6
19.1
23
6
D10.10
ICD-10 Finland
Benign tumor at the base of the tongue
+∞
18.0
17
*
QA1S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in head
198.8
17.8
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.2
17.7
91
351
WZC30
NOMESCO Finland
Teaching
5.6
17.7
58
141
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
29.0
17.4
23
9
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.2
17.3
37
49
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.5
16.0
44
85
EMB10
NOMESCO Finland
Tonsillectomy
12.1
15.9
29
28
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
5.5
15.8
51
120
D37.08
ICD-10 Finland
Tumor of uncertain or unknown nature in other part of lip, oral cavity and pharynx
174.5
15.7
16
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
7.9
15.3
36
55
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
35.1
15.1
19
6
A06AD11
ATC
lactulose; oral
5.0
14.8
53
139
K04.5
ICD-10 Finland
Chronic apical periodontitis
3.8
14.6
78
300
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
8.7
14.2
31
42
ZX070
NOMESCO Finland
Intensity modified radiotherapy
16.5
14.0
22
15
WX402
NOMESCO Finland
General anaesthesia
4.4
13.8
56
166
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
81.1
13.8
15
*
C02.9
ICD-10 Finland
Malignant neoplasm: Tongue, unspecified
150.9
13.6
14
*
PJD51
NOMESCO Finland
Block dissection of cervical lymph nodes
75.3
12.8
14
*
C02.4
ICD-10 Finland
Malignant neoplasm: Lingual tonsil
+∞
12.6
12
*
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
8.7
12.2
26
34
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
32.5
11.8
15
5
C02.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of tongue
127.8
11.6
12
*
R13
ICD-10 Finland
Dysphagia
6.1
11.5
32
62
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
5.6
10.2
30
62
D10.19
ICD-10 Finland
Benign tumor of the tongue UNS
58.2
9.8
11
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
8.9
9.6
20
25
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
8.0
9.5
21
29
TJD20
NOMESCO Finland
Change of gastrostomy tube
+∞
9.5
9
*
8085/3-C01.9
ICD-O-3
Squamous cell carcinoma, HPV positive of base of tongue, NOS
+∞
9.5
9
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
14.7
9.4
15
11
EBA10
NOMESCO Finland
Surgical removal of tooth
4.3
9.1
35
96
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
19.9
9.1
13
7
A04AA55
ATC
palonosetron, combinations; systemic
11.6
9.0
16
15
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
29.1
8.6
11
*
K05.31
ICD-10 Finland
Periodontitis pronounced
3.8
8.6
38
119
SCA04
NOMESCO Finland
Guidance on care of mouth and oral mucosa
94.3
8.5
9
*
K10.26
ICD-10 Finland
Periostitis of jaw (acute)(chronic)(suppurative)
+∞
8.4
8
*
C02.10
ICD-10 Finland
Malignant neoplasm of tip of tongue
+∞
8.4
8
*
WX002
NOMESCO Finland
Sedation and analgesia
2.9
8.3
58
252
ED1AA
NOMESCO Finland
Mandipular X-ray examination
35.1
8.2
10
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
6.0
8.2
22
41
WW500
NOMESCO Finland
Blood transfusion
6.9
8.0
19
30
UGC12
NOMESCO Finland
Flexible bronchoscopy
4.2
7.9
30
82
WF004
NOMESCO Finland
Palliative radiotherapy
12.6
7.7
13
11
Z51.5
ICD-10 Finland
Palliative care
5.8
7.7
21
40
R07.0
ICD-10 Finland
Pain in throat
5.9
7.5
20
37
Z2446
NOMESCO Finland
Social worker
5.9
7.5
20
37
WX707
NOMESCO Finland
Fiberoscopic intubation
83.4
7.5
8
*
K11.70
ICD-10 Finland
Hypoptyalism
83.4
7.5
8
*
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
5.3
7.5
22
46
GD6BD
NOMESCO Finland
Extensive CT of chest and neck
+∞
7.3
7
*
9680/3-C01.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of base of tongue, NOS
+∞
7.3
7
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
7.1
7.3
17
26
ECB20
NOMESCO Finland
Oral alveoplasty
31.4
7.2
9
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
9.4
7.2
14
16
WX110
NOMESCO Finland
Local anesthesy
2.5
7.1
131
937
R21
ICPC
Throat symptom/complaint
3.4
7.0
35
120
UDQ22
NOMESCO Finland
Microlaryngoscopy
11.6
6.9
12
11
T05
ICPC
Feeding problem of adult
41.7
6.8
8
*
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
12.9
6.7
11
9
K05.30
ICD-10 Finland
Periodontitis complex
3.0
6.6
40
156
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.7
6.6
28
85
UJC02
NOMESCO Finland
Rigid oesophagoscopy
15.0
6.5
10
7
Q18.0
ICD-10 Finland
Sinus, fistula and cyst of branchial cleft
72.3
6.5
7
*
QA7S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in jaw or lips
72.3
6.5
7
*
J02AC01
ATC
fluconazole; systemic
2.4
6.5
63
326
UJC20
NOMESCO Finland
Extensive endoscopy to identify diagnosed or suspected primary malignant neoplasm of head or neck
+∞
6.3
6
*
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
4.2
6.3
23
61
SBB10
NOMESCO Finland
Teeth copy
4.3
6.3
22
56

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_BASEOFTONGUE – Malignant neoplasm of base of tongue

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).