Benign neoplasm: Duodenum

CD2_BENIGN_DUODENUM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D13.2&
  • Hospital discharge: ICD-8 21121
  • Cause of death: ICD-10 D13.2&
  • Cause of death: ICD-8 21121

2 out of 7 registries used, show all original rules.

924

4. Check minimum number of events

None

924

5. Include endpoints

None

924

6. Filter based on genotype QC (FinnGen only)

902

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum duodeni

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4501 2253 2225
Only index persons 4114 2085 2029
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.06
Only index persons 0.08 0.08 0.08
Median age at first event (years)
Whole population 66.66 66.94 66.36
Only index persons 66.34 66.64 66.04

-FinnGen-

Key figures

All Female Male
Number of individuals 902 471 431
Unadjusted period prevalence (%) 0.18 0.17 0.20
Median age at first event (years) 66.98 66.70 67.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
924
Matched controls
9240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
4503599627370496.0
307.7
911
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
24.1
307.7
807
2059
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
42.8
232.7
142
39
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
19.7
180.8
147
88
D37.2
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Small intestine
57.5
139.6
79
15
UJF32
NOMESCO Finland
Coloscopy
4.2
102.9
480
1883
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
39.3
95.7
59
16
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
9.6
78.5
97
112
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
20.5
72.5
56
29
JDH05
NOMESCO Finland
Endoscopic polypectomy in duodenum
374.7
70.6
70
*
JLC30
NOMESCO Finland
Pancreatoduodenectomy
26.0
67.1
47
19
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
5.3
63.4
142
307
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
4.3
57.3
170
460
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
23.8
56.6
41
18
UJF92
NOMESCO Finland
Capsular endoscopy
9.6
56.1
68
76
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.6
52.5
138
339
UJF02
NOMESCO Finland
Peroral enteroscopy
22.0
50.8
38
18
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.8
50.7
181
557
JDA05
NOMESCO Finland
Endoscopic polypectomy in stomach or pylorus
67.4
49.8
57
9
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
7.4
48.1
72
104
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.0
47.4
151
428
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
5.2
44.5
98
207
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.5
43.3
176
586
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
9.2
42.6
53
61
A02BC02
ATC
pantoprazole; systemic
3.2
42.4
754
5387
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
9.4
41.9
51
57
D64.9
ICD-10 Finland
Anaemia, unspecified
3.3
41.5
189
674
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
41.5
414
2230
UJK02
NOMESCO Finland
ERCP
6.5
40.4
68
111
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.1
38.9
190
705
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
13.5
35.9
34
26
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.3
35.5
98
248
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
5.1
35.2
77
161
UJF30
NOMESCO Finland
Ileoscopy through colon
3.2
34.5
159
567
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
5.6
34.4
68
130
A02BC05
ATC
esomeprazole; systemic
2.3
34.2
471
2859
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.5
33.6
276
1333
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
4.4
32.9
88
217
WX002
NOMESCO Finland
Sedation and analgesia
2.5
31.4
267
1305
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
30.0
182
753
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.9
29.9
68
147
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
6.3
29.6
51
85
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.2
29.4
131
456
K22.1
ICD-10 Finland
Ulcer of oesophagus
6.4
28.6
48
78
JN3AD
NOMESCO Finland
Abdominal CT examination
2.8
28.5
160
634
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
27.8
222
1047
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
27.0
131
478
K92.1
ICD-10 Finland
Melaena
3.5
26.8
97
296
K30
ICD-10 Finland
Functional dyspepsia
2.8
26.5
148
584
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
26.3
533
3637
A02BC01
ATC
omeprazole; systemic
2.2
26.3
328
1864
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
26.0
272
1438
JFA05
NOMESCO Finland
Endoscopic polypectomy in small intestine
96.2
25.8
28
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.4
25.4
100
322
WX402
NOMESCO Finland
General anaesthesia
2.3
25.2
240
1217
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
9.1
24.3
30
34
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
6.4
23.8
40
65
K31.7
ICD-10 Finland
Polyp of stomach and duodenum
20.2
23.6
35
18
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
22.9
233
1209
TPH07
NOMESCO Finland
Cathetrisation of artery
2.5
22.1
161
721
JDH52
NOMESCO Finland
Endoscopic mucosal or submucosal resection in duodenum
225.1
21.7
22
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.1
21.5
46
94
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.6
21.2
143
617
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
21.1
217
1127
JDH50
NOMESCO Finland
Local excision of lesion of duodenal bulb
214.6
20.7
21
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.3
20.6
55
135
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
4.4
20.4
52
123
WX408
NOMESCO Finland
General anesthesy, balanced
2.0
20.3
286
1672
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.5
19.9
70
209
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
19.9
252
1415
JAH00
NOMESCO Finland
Laparotomy
4.2
19.7
53
131
A02BC03
ATC
lansoprazole; oral
2.0
19.6
328
2031
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
5.0
19.6
43
90
H02AB06
ATC
prednisolone; systemic
1.9
19.2
485
3426
UJD02
NOMESCO Finland
Gastroscopy
3.4
19.1
73
230
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
6.7
18.8
30
46
D50.8
ICD-10 Finland
Other iron deficiency anaemias
6.9
18.8
29
43
C17.0
ICD-10 Finland
Malignant neoplasm: Duodenum
193.8
18.6
19
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.5
18.3
127
554
Z2221
NOMESCO Finland
Medical doctor
2.0
18.3
285
1716
R4190
NOMESCO Finland
Nutritional therapy
3.9
18.1
54
144
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
4.0
18.1
52
135
JDA52
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in stomach or pylorus
53.6
18.0
21
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.1
17.9
218
1201
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.6
17.1
57
164
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
17.1
316
2004
R06.0
ICD-10 Finland
Dyspnoea
1.9
16.8
305
1920
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.8
16.8
92
357
B80
ICPC
Iron deficiency anaemia
4.7
16.7
39
86
C07AB07
ATC
bisoprolol; oral
1.8
16.7
533
3979
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
6.4
16.4
27
43
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
5.0
16.3
35
72
JN4AD
NOMESCO Finland
Body CT examination
2.3
16.0
131
615
WZC00
NOMESCO Finland
Treatment plan or consultation
1.8
15.8
353
2360
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
15.7
205
1152
ZX120
NOMESCO Finland
Intravenous
2.4
15.7
119
539
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.3
15.5
60
191
C03CA01
ATC
furosemide; systemic
1.8
15.4
351
2359
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.8
15.2
82
315
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
25.5
14.7
20
8
WX892
NOMESCO Finland
Monitored bed care
2.5
14.7
100
431
Z51.88
ICD-10 Finland
Other specified medical care
4.5
14.6
36
83
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
14.6
124
590
ZXE00
NOMESCO Finland
One hour or less
1.7
14.5
375
2599
R4110
NOMESCO Finland
Physiotherapy
1.8
14.5
293
1893
AA1AD
NOMESCO Finland
CT of head and brain
1.8
14.4
307
2013
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
11.6
14.3
26
23
SPAT1236
SPAT
Informing family of child’s disability
4.3
14.2
37
89
J01DB01
ATC
cefalexin; oral
2.0
14.0
761
6488
R03AC02
ATC
salbutamol; inhalant
1.7
14.0
507
3844
JN4BD
NOMESCO Finland
Extensive body CT
2.2
13.9
137
691
WX004
NOMESCO Finland
Patient-controlled sedation
30.5
13.9
18
6
Z3231
NOMESCO Finland
Registered nurse
1.8
13.8
281
1814
R13
ICD-10 Finland
Dysphagia
2.5
13.8
92
393
A06AD11
ATC
lactulose; oral
2.0
13.7
174
966
N02AX02
ATC
tramadol; systemic, rectal
1.7
13.4
436
3197
N02BE01
ATC
paracetamol; systemic, rectal
2.4
13.4
843
7498
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
18.6
13.4
20
11
ZXE20
NOMESCO Finland
More than three and less than five hours
2.0
13.4
159
861
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
6.4
13.3
22
35
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.5
13.3
89
381
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
40.7
13.2
16
*
K29.4
ICD-10 Finland
Chronic atrophic gastritis
4.1
13.0
36
91
JLW98
NOMESCO Finland
Other transluminal endoscopic operation on pancreas
28.8
13.0
17
6
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
6.2
13.0
22
36
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.1
13.0
27
54
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
4.5
12.9
31
70
Z3226
NOMESCO Finland
Physiotherapist
1.9
12.7
196
1157
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
3.5
12.7
45
135
Z71.9
ICD-10 Finland
Counselling, unspecified
2.6
12.7
79
326
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
12.6
169
953
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
12.6
374
2667
K29.8
ICD-10 Finland
Duodenitis
11.2
12.6
23
21
21121
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Duodeni
+∞
12.5
12
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
12.5
162
903
K63.8
ICD-10 Finland
Other specified diseases of intestine
20.4
12.5
18
9
N05CF01
ATC
zopiclone; oral
1.7
12.4
325
2238
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.2
12.3
50
164
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.9
12.1
56
198
K29.7
ICD-10 Finland
Gastritis, unspecified
3.1
12.0
50
166
R52.9
ICD-10 Finland
Pain, unspecified
2.2
12.0
106
511
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.5
11.9
79
336
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.3
11.8
91
415
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
11.7
174
1013
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
4.7
11.7
27
59
J46
ICD-10 Finland
Status asthmaticus
3.7
11.6
36
99
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
11.6
170
987
J01FF01
ATC
clindamycin; systemic
1.7
11.5
264
1749
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
13.8
11.5
19
14
R12
ICD-10 Finland
Heartburn
2.4
11.5
84
374
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
4.7
11.5
26
56
K83.0
ICD-10 Finland
Cholangitis
4.7
11.5
26
56
JDH28
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in duodenum
121.5
11.4
12
*
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
11.4
277
1861
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.1
11.4
117
598
R10.0
ICD-10 Finland
Acute abdomen
3.6
11.4
37
105
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.4
184
1100
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.1
11.3
115
586
A46
ICD-10 Finland
Erysipelas
1.9
11.3
155
880
B01AB05
ATC
enoxaparin; parenteral
1.6
11.3
330
2329
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.6
11.2
21
38
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
11.2
628
5193
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
11.1
128
683
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
4.0
11.1
31
79
Z12.1
ICD-10 Finland
Special screening examination for neoplasm of intestinal tract
5.8
11.0
20
35
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.0
11.0
49
170
Z01.7
ICD-10 Finland
Laboratory examination
1.9
11.0
149
842
K92.0
ICD-10 Finland
Haematemesis
3.7
10.9
34
94
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
12.1
10.9
19
16
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
10.8
154
885
P01AB01
ATC
metronidazole; oral, rectal
1.6
10.7
361
2631
A03FA02
ATC
cisapride; oral, rectal
2.2
10.7
90
426
K86.2
ICD-10 Finland
Cyst of pancreas
5.3
10.6
21
40
TJX22
NOMESCO Finland
Excision of local lesion in gastrointestinal endoscopy
111.2
10.4
11
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
10.4
260
1755
J45.8
ICD-10 Finland
Mixed asthma
3.3
10.4
38
117
K83.1
ICD-10 Finland
Obstruction of bile duct
4.5
10.3
25
57
A02BC04
ATC
rabeprazole; oral
2.2
10.3
94
460
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
4.0
10.2
29
75
R02
ICPC
Shortness of breath/dyspnoea
1.9
10.1
138
781
Z53.0
ICD-10 Finland
Procedure not carried out because of contraindication
40.5
10.0
12
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
3.6
10.0
33
95
K22.7
ICD-10 Finland
Barrett oesophagus
4.2
9.9
26
63
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.9
347
2538
3AC01, ,
NOMESCO Finland
7.7
9.9
22
29
SPAT1260
SPAT
Consultation of another employee
1.8
9.9
176
1079
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.6
9.9
58
233
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
4.8
9.8
22
47
L17
ICPC
Foot/toe symptom/complaint
1.6
9.8
277
1926
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.8
9.7
48
176
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
9.7
85
408
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.0
9.7
42
143
K59.0
ICD-10 Finland
Constipation
2.4
9.7
68
297
J45
ICD-10 Finland
Asthma
2.1
9.7
99
505
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
9.7
99
505
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
9.7
258
1765
JDA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in stomach or pylorus
55.6
9.7
11
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
9.6
147
861
R51.80
ICD-10 Finland
Headache
1.9
9.6
137
785
A02BA02
ATC
ranitidine; systemic
1.7
9.6
205
1324
N02AA05
ATC
oxycodone; systemic
1.7
9.6
196
1251
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
9.6
280
1960
ZXA00
NOMESCO Finland
Right side
1.6
9.6
274
1908
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.6
9.6
31
88
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.2
9.5
86
418
ZXD05
NOMESCO Finland
Urgent procedure
1.6
9.5
272
1892
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
9.5
110
587
A07AA02
ATC
nystatin; oral
2.3
9.5
71
319
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.2
9.3
85
415
R03BA01
ATC
beclometasone; inhalant
1.9
9.3
134
771
M54.5
ICD-10 Finland
Low back pain
1.6
9.2
319
2318
R11
ICD-10 Finland
Nausea and vomiting
2.1
9.2
88
437
K86.1
ICD-10 Finland
Other chronic pancreatitis
7.4
9.2
21
29
C03DA01
ATC
spironolactone; oral
1.9
9.2
136
787
A10AE04
ATC
insulin glargine; parenteral
2.0
9.2
102
537
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.5
9.1
57
236
Z98.8
ICD-10 Finland
Other specified postsurgical states
4.8
9.1
20
42
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
9.1
340
2515
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
9.1
48
183
B82
ICPC
Anaemia other/unspecified
3.0
9.1
40
138
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.4
9.1
62
268
R01BA51
ATC
phenylpropanolamine, combinations; oral
2.1
9.0
87
434
JDH25
NOMESCO Finland
Other endoscopic haemostatic procedure in duodenum
37.1
9.0
11
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.6
9.0
50
196
B01AA03
ATC
warfarin; systemic
1.7
8.9
206
1355
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
3.6
8.9
29
83
SPAT1285
SPAT
Provision of consultation response
2.4
8.8
62
272
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
8.8
175
1107
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
50.5
8.7
10
*
ZXE40
NOMESCO Finland
More than seven and less than nine hours
3.3
8.7
32
99
JAH01
NOMESCO Finland
Laparoscopy
2.8
8.7
44
164
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
4.0
8.6
24
61
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
2.6
8.6
49
194
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.6
8.6
50
200
R03BA05
ATC
fluticasone; inhalant
1.7
8.6
161
1000
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.6
407
3160
Z50.1
ICD-10 Finland
Other physical therapy
2.3
8.6
64
288
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.9
8.5
115
646
N03AX12
ATC
[U] gabapentin; oral
1.7
8.5
168
1058
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
8.5
244
1693
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
3.1
8.5
34
111
JFB00
NOMESCO Finland
Partial resection of small intestine
3.9
8.5
24
62
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
8.4
103
560
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
8.4
211
1415
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
8.4
76
370
R53
ICD-10 Finland
Malaise and fatigue
1.6
8.4
221
1501
R03DC03
ATC
montelukast; oral
1.8
8.4
144
872
UJH02
NOMESCO Finland
Anoscopy
2.6
8.4
49
197
R03BB04
ATC
tiotropium bromide; inhalant
1.9
8.3
115
651
8263/2-C17.0
ICD-O-3
Adenocarcinoma in situ in tubulovillous adenoma of duodenum
+∞
8.3
8
*
N03AX16
ATC
[U] pregabalin
1.6
8.3
225
1539
R63.4
ICD-10 Finland
Abnormal weight loss
2.6
8.3
49
198
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
14.6
8.2
13
9
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
8.2
412
3229
J01FA06
ATC
roxithromycin; oral
1.5
8.1
358
2727
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
3.8
8.1
24
64
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
8.1
192
1269
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
33.7
8.1
10
*
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
17.3
8.1
12
7
A10BA02
ATC
metformin; oral
1.5
8.1
290
2114
K55.8
ICD-10 Finland
Other vascular disorders of intestine
10.1
8.0
15
15
WX882
NOMESCO Finland
High dependency care
3.0
8.0
34
115
A10BH01
ATC
sitagliptin; oral
1.9
8.0
109
615
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
7.9
191
1267
B03BA03
ATC
hydroxocobalamin; parenteral
2.2
7.9
66
311
A11CC03
ATC
alfacalcidol; systemic
3.2
7.9
30
95
N06AB04
ATC
citalopram; systemic
1.6
7.9
188
1245
M79.6
ICD-10 Finland
Pain in limb
1.5
7.8
375
2900
D37.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Stomach
7.0
7.8
18
26
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.8
362
2783
E14.9
ICD-10 Finland
Unspecified diabetes mellitus, without complications
3.7
7.8
24
66
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
7.8
236
1655
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
7.8
246
1742
J01MA12
ATC
levofloxacin; systemic
1.6
7.7
186
1233
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
7.7
64
301
N06AX11
ATC
mirtazapine; oral
1.5
7.6
302
2243
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
18.5
7.6
11
6
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.3
7.6
54
238
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
6.2
7.6
19
31
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
8.9
7.6
15
17
D02
ICPC
Abdominal pain epigastric
2.2
7.5
61
284
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
10.1
7.5
14
14
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
10.1
7.5
14
14
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
7.5
239
1693
N30.0
ICD-10 Finland
Acute cystitis
1.7
7.5
143
892
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.2
7.5
29
93
WW500
NOMESCO Finland
Blood transfusion
2.5
7.5
47
196
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.5
7.5
18
41
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
7.4
114
667
JFA25
NOMESCO Finland
Endoscopic contact coagulation in small intestine
80.7
7.4
8
*
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.3
7.4
54
241
B01AB04
ATC
dalteparin; parenteral
2.3
7.4
54
241
OAB50, ,
SPAT
2.2
7.4
61
287
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
7.3
74
376
K56.7
ICD-10 Finland
Ileus, unspecified
3.7
7.3
23
64
8140/3-C17.0
ICD-O-3
Adenocarcinoma, NOS, of duodenum
+∞
7.3
7
*
R03DA04
ATC
theophylline; systemic, rectal
2.2
7.2
59
276
-, ,
ICD-10 Finland
3.1
7.2
29
95
A41.9
ICD-10 Finland
Sepsis, unspecified
2.6
7.2
41
163
JLB28
NOMESCO Finland
Endoscopic internal drainage of pancreatic duct
20.2
7.1
10
5
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
7.1
103
592
RD210, ,
NOMESCO Finland
4.1
7.1
19
47
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
4.1
7.1
19
47
H02AB07
ATC
prednisone; oral
1.7
7.1
130
802
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
10.1
7.0
13
13
XW000
NOMESCO Finland
Bone marrow biopsy
2.4
7.0
49
214
T90
ICPC
Diabetes non-insulin dependent
1.5
7.0
238
1705
R03AC13
ATC
formoterol; inhalant
2.2
7.0
57
267
K59.09
ICD-10 Finland
Constipation, unspecified
2.0
6.9
73
377
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.0
6.9
78
413
205
Kela drug reimbursment
Chronic hypertension
1.5
6.9
280
2085
XF404
NOMESCO Finland
Ambulatory ECG
1.8
6.8
95
539
M10.9
ICD-10 Finland
Gout, unspecified
2.0
6.8
74
387
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.1
6.8
27
88
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
5.7
6.8
18
32
I50.9
ICD-10 Finland
Heart failure, unspecified
1.7
6.8
146
940
TK800
NOMESCO Finland
Hemodialysis
3.2
6.8
26
83
M04AA01
ATC
allopurinol; systemic
1.7
6.7
136
860
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.2
6.7
57
271
N05BA04
ATC
oxazepam; oral
1.5
6.7
229
1641
A10AB05
ATC
insulin aspart; parenteral
2.0
6.7
73
382
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
6.7
155
1017
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
6.6
125
776
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.5
6.6
18
33
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
5.5
6.6
18
33
K55.2
ICD-10 Finland
Angiodysplasia of colon
7.9
6.6
14
18
D01
ICPC
Abdominal pain/cramps general
1.8
6.6
96
552
A03CA02
ATC
clidinium and psycholeptics; oral
2.1
6.6
61
300
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.9
6.6
30
106
R50.9
ICD-10 Finland
Fever, unspecified
1.7
6.6
134
850
J02AC01
ATC
fluconazole; systemic
1.5
6.5
301
2291
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.6
6.5
36
141
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
6.5
597
5156
K29.1
ICD-10 Finland
Other acute gastritis
3.7
6.5
20
55
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.2
6.5
16
26
C09CA01
ATC
losartan; oral
1.5
6.5
253
1864
R01AD58
ATC
fluticasone, combinations; nasal
1.6
6.4
167
1124
JKA20
NOMESCO Finland
Cholecystectomy
2.7
6.4
34
130
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.9
6.4
79
431
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
14.4
6.4
10
7
WX704
NOMESCO Finland
Intubation
2.0
6.4
72
381
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.7
6.4
32
119
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.4
6.4
41
173
K85.8
ICD-10 Finland
Other acute pancreatitis
6.6
6.3
15
23
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
6.3
71
375
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
8.2
6.3
13
16
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.7
6.3
107
644
K20
ICD-10 Finland
Oesophagitis
3.3
6.3
23
71
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
9.3
6.3
12
13
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.3
6.3
46
206
L04AX01
ATC
azathioprine; systemic
2.5
6.3
39
162
8936/1-C17.0
ICD-O-3
Gastrointestinal stromal tumor, NOS, of duodenum
+∞
6.3
6
*
C24.1
ICD-10 Finland
Malignant neoplasm: Ampulla of Vater
+∞
6.3
6
*
21139
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Coli NUD
+∞
6.3
6
*
JKC50
NOMESCO Finland
Excision of papilla of Vater and anastomosis of bile duct to duodenum or jejunum
+∞
6.3
6
*
JDA22
NOMESCO Finland
Endoscopic ligature of varices of stomach
26.9
6.2
8
*
JFA73
NOMESCO Finland
Excision of lesion of small intestine
26.9
6.2
8
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
6.2
125
789
M48.0
ICD-10 Finland
Spinal stenosis
1.6
6.2
136
878
E66.8
ICD-10 Finland
Other obesity
2.4
6.2
43
188
R96
ICPC
Asthma
1.8
6.2
91
526
R03AC03
ATC
terbutaline; inhalant
1.7
6.2
119
743
C10AC01
ATC
colestyramine; oral
2.8
6.2
30
110
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.6
6.2
159
1069
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
6.1
123
777
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
3.8
6.1
18
48
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.6
6.1
33
128
WZC30
NOMESCO Finland
Teaching
1.6
6.1
148
982
M03BX02
ATC
tizanidine; oral
1.4
6.0
508
4293
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.0
217
1570

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
464
1155
7.06
194.72
2.3
1.2
—
—
—
0
0
439
2121
3.04
59.40
3.3
2.2
3.73
3.12
mg/l
3.03
392
1807
686
4312
3.29
56.56
9.4
6.5
12.81
11.71
umol/l
0.50
667
4101
618
3668
3.07
56.34
8.3
4.8
34.37
35.07
g/l
2.22
591
3412
233
808
3.52
54.74
3.0
2.2
0.21
0.21
g/l
0.51
220
756
646
4098
2.92
48.94
22.9
17.0
1.27
1.29
inr
0.17
149
1145
249
966
3.16
48.07
3.4
4.3
8.37
25.01
ug/l
1.03
201
816
472
2581
2.69
47.54
4.7
2.5
61.49
92.39
u/l
0.49
455
2380
133
348
4.30
46.45
3.0
3.5
27.61
4094.22
u/ml
0.80
106
298
700
4850
2.83
40.87
7.5
5.0
6.86
6.77
mmol/l
0.57
669
4593
290
1322
2.74
40.82
3.6
2.5
11.07
12.78
umol/l
3.30
273
1237
201
756
3.12
40.27
3.9
2.5
57.83
40.13
u/l
0.52
187
640
226
919
2.93
39.34
4.7
2.8
9.23
8.55
umol/l
0.11
202
808
271
1219
2.73
38.90
3.7
2.5
2.36
2.31
g/l
0.54
252
1138
103
253
4.46
38.84
1.6
1.5
206.97
279.34
ug/g
3.07
76
155
521
3194
2.45
38.45
4.8
2.8
103.49
150.12
ug/l
5.32
481
2903
260
1159
2.73
37.87
3.7
2.5
19.47
22.51
%
2.36
221
991
215
907
2.79
34.51
1.5
1.3
—
—
—
0
0
234
1034
2.69
34.28
2.7
2.6
1.92
1.82
%
0.60
215
923
615
4201
2.39
33.56
9.5
7.0
1.20
1.21
mmol/l
3.22
550
3596
800
6201
3.16
33.25
12.3
7.9
88.41
79.49
u/l
2.05
781
5818
564
3725
2.32
33.12
4.3
2.6
—
—
—
0
0
434
2581
2.29
32.67
4.0
2.5
—
—
—
0
0
420
2468
2.29
32.49
4.9
3.3
32.46
34.22
u/l
0.46
403
2344
583
3945
2.29
31.73
7.4
5.8
1.74
1.92
e9/l
2.61
532
3486
574
3872
2.27
31.29
7.4
5.7
0.04
0.04
e9/l
0.56
514
3357
573
3865
2.27
31.20
7.4
5.7
0.60
0.60
e9/l
0.00
513
3347
587
4009
2.27
30.86
7.6
5.9
0.20
0.19
e9/l
0.67
532
3518
125
419
3.29
29.90
1.8
1.9
1.61
1.56
g/l
0.21
106
369
636
4521
2.31
29.90
10.4
9.2
4.49
4.16
e9/l
2.64
580
3967
542
3633
2.19
29.17
7.4
6.3
—
—
—
0
0
526
3518
2.15
28.04
2.6
2.1
90.42
94.87
pmol/l
1.47
312
1780
75
188
4.25
27.39
2.9
3.6
424.93
1959.65
u/ml
0.57
63
178
394
2404
2.11
26.22
5.9
4.4
—
—
—
0
0
178
787
2.56
25.37
2.6
2.7
71.98
70.60
e9/l
0.14
132
621
532
3659
2.07
25.29
7.4
5.8
59.26
57.84
%
2.06
498
3427
530
3659
2.05
24.71
7.7
6.2
8.72
8.83
%
0.29
498
3418
536
3721
2.05
24.54
7.6
6.1
25.43
26.83
%
2.32
503
3482
526
3638
2.04
24.20
7.4
5.9
2.97
2.85
%
0.48
493
3396
211
1035
2.35
23.83
8.2
7.6
5.09
5.11
kpa
0.12
202
992
211
1036
2.34
23.77
8.2
7.5
11.56
11.85
kpa
0.42
202
996
737
5813
2.32
23.55
5.5
4.3
15.96
13.43
mm/h
3.41
690
5333
236
1222
2.25
23.41
2.6
2.0
—
—
—
0
0
299
1703
2.12
23.29
1.8
1.8
1244.28
1192.75
nmol/l
0.40
237
1275
209
1033
2.32
23.13
8.2
7.6
1.22
1.17
mmol/l
0.07
177
814
545
3861
2.00
22.92
9.2
6.2
1.20
1.21
mmol/l
4.31
514
3509
344
2076
2.05
22.84
6.7
4.0
85.15
87.98
%
1.12
337
2028
176
818
2.42
22.33
1.8
2.2
151.58
142.73
ug/g
0.16
148
641
178
833
2.41
22.24
4.9
3.6
1.53
2.02
mmol/l
1.03
155
689
221
1139
2.24
22.02
7.0
5.7
1.05
1.03
mmol/l
0.42
203
1046
391
2495
1.98
21.97
6.0
4.1
7.41
7.40
ph
0.64
55
471
254
1385
2.15
21.97
3.9
3.3
0.80
0.82
mmol/l
0.68
235
1296
507
3535
1.96
21.96
7.4
5.9
0.68
0.66
%
0.28
475
3294
330
1999
2.01
21.39
8.0
6.9
—
—
—
0
0
342
2106
1.99
21.09
1.8
1.6
21.84
20.88
nmol/l
0.26
300
1760
324
1975
1.99
20.44
4.1
2.4
—
—
—
0
0
161
766
2.33
19.19
8.9
7.3
10.36
10.29
mmol/l
0.04
156
727
406
2716
1.88
19.05
3.6
3.1
1926.17
1382.30
ng/l
0.84
354
2340
129
560
2.52
18.81
9.2
9.7
93.84
93.94
%
0.08
129
555
154
740
2.30
17.86
8.7
8.7
—
—
—
0
0
134
609
2.40
17.64
7.2
4.6
—
—
—
0
0
274
1644
1.95
17.64
5.3
4.1
120.99
353.33
ng/l
2.81
231
1365
361
2373
1.86
17.52
4.2
3.3
0.84
0.50
e6/l
0.59
300
1831
477
3416
1.82
17.48
13.2
10.1
0.00
0.00
e9/l
0.45
408
2819
348
2274
1.85
17.12
4.3
3.2
—
—
—
0
0
421
2922
1.81
16.96
4.9
3.9
34.59
104.51
e6/l
2.17
329
2138
291
1801
1.90
16.95
3.2
2.6
4.60
4.92
e6/l
0.28
261
1628
250
1486
1.94
16.37
3.1
2.9
2.61
1.09
e6/l
0.58
158
883
180
952
2.11
16.35
2.2
1.7
—
—
—
0
0
414
2899
1.78
15.86
3.1
3.6
2.33
2.35
mmol/l
2.00
372
2530
123
565
2.36
15.74
9.2
9.5
0.61
0.69
%
1.49
123
559
448
3219
1.76
15.62
2.8
2.3
75.74
78.97
nmol/l
1.61
405
2834
374
2552
1.78
15.59
4.3
3.4
28.72
95.28
e6/l
1.76
314
1992
861
7639
2.86
15.56
30.1
16.0
26.62
25.50
mg/l
0.44
767
6144
130
616
2.29
15.48
2.4
2.6
10.25
10.66
g/l
0.41
122
561
437
3142
1.74
15.01
2.6
2.2
—
—
—
0
0
122
570
2.31
15.00
9.2
9.3
1.37
1.35
%
0.06
122
564
230
1372
1.90
14.70
1.6
1.5
2.71
2.54
g/l
0.43
141
821
272
1712
1.83
14.67
3.7
3.0
509.60
544.17
mosm/kgh2o
1.96
235
1474
429
3082
1.73
14.67
4.8
3.7
5.62
5.81
ph
0.33
13
178
149
763
2.14
14.62
3.7
3.1
224.37
223.74
ng/l
0.01
134
699
89
364
2.60
14.60
2.5
1.9
3.60
2.14
ug/l
0.49
77
323
180
990
2.02
14.58
1.4
1.3
401.82
464.62
titre
0.28
44
221
108
485
2.39
14.52
2.0
1.7
1.33
1.52
g/l
0.42
102
444
515
3901
1.72
14.45
4.8
3.9
0.00
0.00
estimate
0.75
81
796
673
5509
1.82
14.24
5.4
4.5
—
—
—
0
0
513
3895
1.71
14.15
6.7
5.2
0.00
0.00
estimate
-0.00
73
741
43
117
3.81
14.03
1.5
1.6
0.84
0.77
g/l
0.07
32
90
372
2592
1.73
14.03
2.4
2.2
278.92
231.77
u/l
0.24
354
2435
701
5824
1.84
13.95
4.8
3.9
15.10
15.00
pmol/l
0.48
642
5211
608
4847
1.74
13.94
5.0
3.2
74.86
54.02
u/l
2.93
568
4468
369
2572
1.72
13.85
3.2
3.3
930.57
308.92
mg/l
1.00
255
1647
515
3943
1.69
13.51
4.9
3.9
0.00
0.00
estimate
0.50
72
720
268
1718
1.79
13.42
1.9
1.6
1.24
1.28
mg/l
0.09
212
1340
144
762
2.05
12.88
2.8
2.9
65.55
66.32
g/l
0.57
133
694
85
362
2.48
12.80
8.9
4.6
—
—
—
0
0
149
802
2.02
12.71
3.2
2.6
5.26
7.10
ug/l
1.12
135
705
371
2635
1.68
12.70
3.7
3.3
—
—
—
0
0
681
5682
1.75
12.47
5.4
4.2
—
—
—
0
0
440
3292
1.64
12.14
5.2
3.9
48.31
51.01
ng/l
0.05
344
2479
80
340
2.48
12.10
6.7
3.7
1.56
1.42
mmol/l
0.31
80
332
133
705
2.04
11.79
1.8
1.5
—
—
—
0
0
101
482
2.23
11.74
1.2
1.3
—
—
—
0
0
376
2734
1.63
11.43
3.8
3.8
21.39
8.62
mg/mmol
2.35
250
1723
309
2153
1.65
11.04
3.5
2.8
2541.12
8473.21
umol/l
2.45
274
1851
136
745
1.97
10.96
1.8
1.5
—
—
—
0
0
275
1862
1.68
10.96
4.7
3.9
—
—
—
0
0
89
415
2.27
10.93
1.4
1.3
—
—
—
0
0
217
1379
1.75
10.90
3.6
3.1
2.93
2.20
e6/l
0.46
129
782
63
252
2.61
10.81
1.6
1.6
—
—
—
0
0
116
610
2.03
10.48
1.5
1.4
—
—
—
0
0
98
488
2.13
10.23
9.8
10.2
—
—
—
0
0
92
450
2.16
10.05
4.2
3.3
24.86
25.22
mmol/l
0.42
92
438
360
2653
1.58
10.00
3.1
3.2
7.33
7.30
mmol/l
0.04
299
2198
232
1535
1.68
9.96
1.3
1.2
2.88
1.75
u/ml
0.21
56
410
256
1739
1.65
9.92
5.7
4.3
1.01
1.02
kg/l
2.66
57
251
91
447
2.15
9.84
2.8
2.4
—
—
—
0
0
872
8044
2.49
9.83
35.1
19.0
139.25
139.65
mmol/l
4.34
860
7837
873
8065
2.49
9.67
35.1
19.1
3.98
3.99
mmol/l
0.69
859
7849
61
255
2.49
9.57
1.3
1.2
—
—
—
0
0
247
1685
1.64
9.34
3.1
3.2
2.46
2.46
mmol/l
0.02
218
1490
119
657
1.93
9.33
2.5
2.6
—
—
—
0
0
93
473
2.07
9.18
6.7
8.4
25.41
25.06
mmol/l
0.49
93
468
64
282
2.36
8.97
7.4
3.9
3.82
3.93
mmol/l
0.74
64
277
738
6494
1.68
8.96
34.5
19.0
15.53
15.30
%
0.52
732
6385
26
69
3.85
8.83
1.3
1.3
7.64
7.50
g/l
0.05
19
51
26
69
3.85
8.83
1.3
1.3
0.51
0.48
g/l
0.13
19
50
26
69
3.85
8.83
1.3
1.3
2.98
2.80
g/l
0.17
18
51
127
731
1.85
8.76
4.6
3.6
—
—
—
0
0
26
72
3.69
8.33
1.2
1.3
—
—
—
0
0
782
7055
1.71
7.85
6.0
4.8
1.92
2.16
mu/l
0.72
724
6356
65
309
2.19
7.64
3.1
3.9
123.97
73.08
mg/l
0.35
55
249
35
124
2.89
7.60
1.3
1.5
129.75
104.24
u/ml
1.46
12
17
65
310
2.18
7.58
3.1
3.9
37.19
43.48
mg/l
0.20
56
252
117
687
1.80
7.54
5.2
3.7
114.02
89.02
ng/l
1.71
97
602
253
1827
1.53
7.23
1.9
1.7
458.64
23295508.37
pmol/l
1.45
224
1481
53
237
2.31
7.22
2.8
4.0
—
—
—
0
0
136
845
1.71
7.21
1.9
1.6
—
—
—
0
0
84
450
1.95
7.19
1.5
1.4
—
—
—
0
0
121
730
1.76
7.11
2.5
2.1
321.12
372.27
nmol/l
2.08
108
673
188
1279
1.59
6.97
1.3
1.3
39.91
35.97
iu/ml
0.13
60
422
27
89
3.09
6.66
1.1
1.2
—
—
—
0
0
35
137
2.62
6.35
1.3
1.4
—
—
—
0
0
65
333
2.02
6.33
2.6
2.7
9.84
10.41
g/l
0.41
57
298
178
1222
1.57
6.31
1.3
1.3
37.45
11.98
u/ml
0.46
62
442
50
233
2.21
6.21
2.7
2.4
227.31
90.01
ug/min
0.67
38
135
57
280
2.10
6.21
2.1
2.0
22.25
21.72
s
0.33
52
254
30
111
2.76
6.07
1.1
1.1
—
—
—
0
0
863
8127
1.94
5.98
17.6
11.3
26.85
25.74
u/l
1.07
846
7810
16
30
5.41
5.86
1.7
1.2
8.99
16.15
g/l
2.74
11
20
791
7283
1.60
5.85
8.4
6.3
41.50
40.50
mmol/mol
2.03
737
6673
88
518
1.77
5.63
1.2
1.2
—
—
—
0
0
841
7886
1.74
5.52
29.6
15.2
—
—
—
0
0
37
161
2.35
5.41
1.1
1.2
—
—
—
0
0
46
222
2.13
5.27
1.1
1.1
—
—
—
0
0
15
30
5.06
5.27
3.7
2.6
—
—
—
0
0
147
1013
1.54
5.07
1.4
1.3
—
—
—
0
0
39
181
2.21
4.94
1.2
1.2
—
—
—
0
0
48
242
2.04
4.93
3.3
3.2
—
—
—
0
0
110
727
1.58
4.56
1.3
1.4
—
—
—
0
0
25
99
2.57
4.49
2.4
2.4
—
—
—
0
0
11
19
5.84
4.45
2.9
5.5
—
—
—
0
0
68
399
1.76
4.44
3.0
3.1
4.21
4.45
pmol/l
1.47
60
343
24
94
2.59
4.41
1.3
1.2
89.70
75.14
u/ml
—
5
5
16
50
3.24
4.35
1.1
1.3
1.23
1.15
promille
—
10
43
52
284
1.88
4.28
2.8
2.6
36.24
37.24
g/l
0.49
44
250
21
78
2.73
4.27
1.3
1.1
2.53
1.47
u/ml
0.28
13
41
28
121
2.36
4.21
2.2
2.8
—
—
—
0
0
14
41
3.45
4.19
2.4
2.5
798.57
1263.66
u/ml
0.61
14
41
27
115
2.39
4.19
2.0
1.2
—
—
—
0
0
27
116
2.37
4.12
1.1
1.2
295.65
315.96
u/ml
0.12
17
69
873
8375
1.77
3.89
45.5
23.7
38.54
39.78
%
5.76
806
7761
26
113
2.34
3.88
1.5
1.3
1903.95
1732.95
e6/l
0.11
19
80
11
23
4.83
3.88
1.0
1.0
—
—
—
0
0
24
101
2.41
3.84
1.3
1.3
139606.73
164035.67
e6/l
0.09
15
54
873
8379
1.76
3.83
45.4
23.6
249.17
244.52
e9/l
1.05
858
8143
873
8380
1.76
3.81
45.1
23.5
30.08
30.41
pg
4.89
866
8239
873
8380
1.76
3.81
45.2
23.5
91.07
91.49
fl
1.63
866
8240
873
8381
1.75
3.79
45.3
23.6
4.33
4.44
e12/l
7.70
853
8124
16
55
2.94
3.75
2.1
1.7
—
—
—
0
0
873
8384
1.75
3.75
45.7
23.7
128.71
134.27
g/l
17.63
865
8238
266
2153
1.33
3.66
5.4
4.2
0.00
0.01
estimate
0.69
69
710
308
2547
1.31
3.63
4.8
4.2
—
—
—
0
0
872
8380
1.72
3.62
45.4
23.6
7.04
6.76
e9/l
3.24
853
8122
48
275
1.79
3.44
9.4
6.2
1.51
1.34
mmol/l
0.44
42
246
26
120
2.20
3.41
1.0
1.1
—
—
—
0
0
242
1950
1.33
3.40
1.5
1.3
—
—
—
0
0
10
23
4.38
3.31
1.1
1.1
—
—
—
0
0
18
71
2.57
3.31
1.3
1.0
0.90
4.55
u/ml
—
9
26
11
28
3.96
3.29
3.4
2.6
—
—
—
0
0
31
156
2.02
3.28
1.8
1.6
—
—
—
0
0
800
7578
1.41
3.22
5.8
5.0
6.27
6.04
mmol/l
4.52
731
6810
41
230
1.82
3.17
5.2
5.3
—
—
—
0
0
97
682
1.47
3.06
1.6
1.5
—
—
—
0
0
18
74
2.46
3.06
1.7
1.4
12.80
30.91
%
—
10
46
15
58
2.61
2.88
1.1
1.2
—
—
—
0
0
130
976
1.39
2.87
1.9
1.4
—
—
—
0
0
23
450
0.50
2.85
1.3
1.4
—
—
—
0
0
21
96
2.22
2.85
1.3
1.4
—
—
—
0
0
67
444
1.55
2.81
4.6
4.0
—
—
—
0
0
248
2053
1.28
2.80
4.5
3.6
—
—
—
0
0
16
65
2.49
2.80
1.5
1.1
1.51
1.53
nmol/l
0.03
16
58
8
18
4.47
2.80
1.1
1.2
—
—
—
0
0
15
59
2.57
2.79
1.2
1.0
0.69
0.47
u/ml
—
9
27
106
772
1.42
2.79
1.6
1.5
—
—
—
0
0
16
66
2.45
2.72
1.6
1.3
—
—
—
0
0
15
60
2.52
2.71
2.3
2.3
—
—
—
0
0
65
434
1.54
2.65
2.8
2.8
0.12
0.22
e6/l
0.98
65
425
19
86
2.23
2.65
2.1
1.4
—
—
—
0
0
74
509
1.49
2.63
2.0
3.0
8.12
6.48
e9/l
0.15
53
401
97
707
1.42
2.56
4.5
4.2
1.28
0.95
%
0.23
36
258
15
62
2.44
2.55
1.5
1.1
—
—
—
0
0
24
122
1.99
2.52
1.0
1.0
—
—
—
0
0
16
69
2.34
2.49
1.3
1.1
0.35
0.79
u/ml
—
8
24
8
21
3.83
2.46
2.4
1.2
96.25
71.57
nmol/24h
—
8
21
34
196
1.76
2.46
1.3
1.2
1.93
2.93
u/ml
—
6
26
13
51
2.57
2.45
1.2
1.0
—
—
—
0
0
19
92
2.09
2.28
1.4
1.3
—
—
—
0
0
53
353
1.53
2.22
1.3
1.2
—
—
—
0
0
27
150
1.82
2.22
1.6
1.3
69.35
63.21
mmol/l
0.27
20
129
10
35
2.88
2.21
1.1
1.0
—
—
—
0
0
25
137
1.85
2.15
1.8
2.2
—
—
—
0
0
93
699
1.37
2.08
4.1
3.8
1.22
1.23
mmol/l
0.25
86
611
44
286
1.57
2.07
1.5
1.5
—
—
—
0
0
20
104
1.94
2.01
1.3
1.2
16.57
5.93
u/ml
—
7
46
10
38
2.65
2.01
1.3
1.0
—
—
—
0
0
7
21
3.35
1.96
1.1
1.3
—
—
—
0
0
10
39
2.58
1.94
7.4
5.3
—
—
—
0
0
27
157
1.74
1.94
2.9
2.8
—
—
—
0
0
5
11
4.56
1.94
1.4
1.4
52.40
35.36
umol/l
—
5
11
84
631
1.36
1.90
4.1
4.1
0.67
0.63
%
0.08
30
217
8
28
2.87
1.86
6.2
2.3
—
—
—
0
0
87
662
1.35
1.82
4.6
4.3
0.33
0.12
%
0.38
27
214
35
224
1.58
1.78
3.4
3.2
0.74
0.81
nmol/l
0.54
26
182
19
102
1.88
1.77
1.3
1.2
—
—
—
0
0
28
172
1.65
1.69
6.2
4.7
8.84
8.35
kpa
0.71
28
167
18
317
0.56
1.68
1.7
1.4
—
—
—
0
0
12
55
2.20
1.68
2.0
2.1
—
—
—
0
0
6
19
3.17
1.66
1.7
1.5
—
—
—
0
0
16
83
1.94
1.65
1.1
1.2
—
—
—
0
0
25
150
1.69
1.64
4.0
2.8
—
—
—
0
0
58
421
1.40
1.64
1.2
1.2
79.26
138.09
iu/ml
1.40
22
161
81
622
1.33
1.62
4.0
4.3
0.00
0.62
%
0.68
19
177
5
14
3.58
1.61
1.6
1.4
—
—
—
0
0
25
152
1.66
1.58
1.3
1.5
—
—
—
0
0
32
208
1.56
1.56
2.3
1.7
17857.96
17523.96
e6/l
0.02
26
150
18
100
1.82
1.54
1.7
1.6
58.00
62.85
%
—
10
67
12
58
2.08
1.49
1.2
1.2
—
—
—
0
0
32
211
1.54
1.47
1.7
1.7
—
—
—
0
0
26
163
1.61
1.47
4.8
4.1
—
—
—
0
0
27
171
1.60
1.47
6.2
4.7
4.97
5.01
kpa
0.08
27
166
23
140
1.66
1.46
1.8
1.5
—
—
—
0
0
17
95
1.80
1.43
1.3
1.2
—
—
nmol/l
—
0
0
26
165
1.59
1.41
3.2
2.0
69.57
61.24
%
0.99
26
165
11
53
2.09
1.39
1.0
1.2
—
—
—
0
0
20
119
1.70
1.38
1.9
2.2
30.75
32.60
pg
1.08
20
119
72
559
1.31
1.36
3.9
3.9
5.15
5.18
kpa
0.10
67
537
42
299
1.42
1.35
2.9
3.1
0.44
0.23
g/l
0.73
22
116
800
7768
1.22
1.29
6.2
5.3
2.43
2.68
mmol/l
7.57
720
7052
8
37
2.17
1.21
1.6
1.2
6.25
6.52
mmol/l
—
8
37
15
250
0.59
1.20
1.8
1.6
—
—
—
0
0
17
101
1.70
1.20
1.5
1.6
—
—
—
0
0
7
30
2.34
1.12
2.0
2.7
68000.00
38983.50
ug/l
—
7
30
221
2458
0.87
1.07
3.5
3.1
—
—
—
0
0
776
7544
1.18
1.06
5.3
4.7
1.38
1.46
mmol/l
5.84
694
6827
7
34
2.07
1.03
2.6
3.7
—
—
—
0
0
12
202
0.59
1.02
1.2
1.2
—
—
—
0
0
23
155
1.50
1.02
1.7
1.8
3.92
4.73
mmol/24h
0.60
17
133
751
7290
1.16
1.01
4.9
4.2
1.36
1.30
mmol/l
1.67
669
6536
7
35
2.01
1.00
1.6
1.3
112.29
165.90
mmol/24h
—
7
35
29
206
1.42
0.99
3.1
2.6
—
—
—
0
0
8
144
0.55
0.93
1.3
1.8
—
—
—
0
0
779
7600
1.16
0.89
5.4
4.7
4.30
4.58
mmol/l
11.96
702
6940
6
29
2.08
0.89
1.5
1.2
—
—
—
0
0
6
29
2.08
0.89
3.2
2.1
—
—
—
0
0
319
2959
1.12
0.89
5.0
5.3
2.05
2.94
ug/l
1.69
279
2629
8
44
1.83
0.86
1.8
1.3
—
—
—
0
0
51
408
1.26
0.84
3.9
4.0
—
—
—
0
0
14
89
1.58
0.81
1.2
1.2
—
—
—
0
0
16
106
1.52
0.79
1.1
1.1
—
20.62
—
0
5
0
26
0.00
0.78
0.0
1.5
—
—
—
0
0
68
569
1.21
0.76
2.1
2.2
14.89
13.00
nmol/l
0.25
53
498
10
59
1.70
0.76
1.3
1.1
—
—
—
0
0
13
83
1.57
0.75
1.6
1.2
—
—
—
0
0
5
24
2.09
0.74
1.4
1.2
—
—
—
0
0
9
55
1.64
0.73
2.2
3.2
—
—
—
0
0
5
25
2.01
0.72
1.0
1.0
3050.60
1560.08
miu/ml
—
5
25
9
56
1.61
0.72
2.7
1.6
39.11
36.95
%
—
9
56
10
60
1.67
0.72
1.5
1.1
30.09
34.62
mmol/l
—
10
55
22
160
1.38
0.70
1.6
1.6
—
—
—
0
0
9
59
1.53
0.68
2.0
1.9
—
—
—
0
0
13
86
1.52
0.66
1.1
1.3
—
—
—
0
0
13
87
1.50
0.63
2.3
3.0
—
—
—
0
0
8
50
1.61
0.61
3.0
1.6
0.89
1.02
g/l
—
8
50
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
11
72
1.53
0.59
1.4
1.5
14.05
10.85
%
2.93
11
72
18
134
1.35
0.53
2.6
1.4
281.56
285.76
mu/l
0.02
18
125
6
39
1.54
0.53
1.3
1.3
—
—
—
0
0
6
39
1.54
0.53
1.0
1.1
—
8.00
—
0
7
15
109
1.38
0.51
3.7
2.5
—
—
—
0
0
11
75
1.47
0.51
1.2
1.9
—
—
—
0
0
14
102
1.38
0.47
1.9
1.3
—
—
—
0
0
26
209
1.25
0.47
1.5
1.3
550.54
536.98
mg/l
0.08
26
196
7
48
1.46
0.47
1.9
1.5
80.43
83.04
umol/l
—
7
48
7
50
1.40
0.45
1.3
1.2
—
—
—
0
0
18
139
1.30
0.44
1.6
1.2
15.46
9.96
u/l
0.44
12
106
21
262
0.80
0.43
1.1
1.1
—
—
—
0
0
63
558
1.14
0.42
3.0
3.1
—
—
—
0
0
8
58
1.38
0.41
1.4
1.1
—
—
—
0
0
41
352
1.17
0.41
4.1
4.3
24.43
25.13
mmol/l
0.57
35
330
22
177
1.25
0.40
3.6
2.7
16.09
16.01
%
0.04
12
95
8
61
1.31
0.39
1.0
1.1
—
—
—
0
0
5
37
1.35
0.37
12.6
11.8
—
—
—
0
0
61
677
0.89
0.34
4.0
3.9
—
—
—
0
0
6
47
1.28
0.32
3.8
1.8
—
—
—
0
0
6
47
1.28
0.32
1.8
1.7
—
—
—
0
0
22
183
1.21
0.32
2.9
2.3
122.81
128.67
g/l
0.67
16
139
7
54
1.30
0.30
3.0
2.1
—
—
—
0
0
16
129
1.24
0.30
1.8
1.3
—
—
—
0
0
164
1728
0.94
0.30
3.1
3.2
0.62
0.77
ug/l
2.03
126
1191
19
157
1.21
0.29
1.4
1.3
—
—
—
0
0
5
71
0.70
0.26
1.0
1.1
—
—
—
0
0
42
380
1.11
0.23
1.3
1.3
—
—
—
0
0
223
2152
1.05
0.23
1.6
1.7
1.39
1.37
mmol/l
0.19
200
1779
20
172
1.17
0.22
1.5
1.6
5.84
5.58
iu/l
—
5
50
0
11
0.00
0.21
0.0
1.0
—
6.56
—
0
11
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
14
117
1.20
0.20
1.1
1.2
—
—
—
0
0
6
52
1.15
0.19
1.5
2.1
8.83
9.63
mmol/l
—
6
52
10
81
1.24
0.19
1.6
1.2
—
—
—
0
0
6
53
1.13
0.18
1.8
2.4
13.17
13.20
%
—
6
53
5
70
0.71
0.16
1.0
1.1
—
—
—
0
0
39
362
1.08
0.14
2.0
1.9
—
—
—
0
0
11
93
1.18
0.14
2.0
2.5
1.92
1.38
g/24h
—
6
43
10
84
1.19
0.14
1.9
1.4
—
—
—
0
0
17
153
1.11
0.11
3.9
2.8
—
—
—
0
0
5
45
1.11
0.10
1.2
1.3
131.94
151.88
pmol/l
—
5
45
5
46
1.09
0.09
1.2
1.5
—
—
—
0
0
7
66
1.06
0.08
1.7
2.1
2.47
3.29
ug/l
—
7
60
22
206
1.07
0.07
1.1
1.1
—
—
—
0
0
10
90
1.11
0.05
1.4
2.0
—
—
—
0
0
16
149
1.08
0.05
2.8
3.5
60.06
58.59
%
0.14
16
149
12
130
0.92
0.04
1.8
2.6
—
—
—
0
0
23
222
1.04
0.02
2.6
2.6
—
—
—
0
0
11
117
0.94
0.01
1.1
1.5
—
—
—
0
0
11
117
0.94
0.01
1.1
1.5
—
—
—
0
0
39
382
1.02
0.01
3.7
2.7
—
—
—
0
0
15
143
1.05
0.01
2.5
3.2
4.39
4.52
e9/l
0.06
15
143
11
116
0.95
0.00
1.1
1.5
—
—
—
0
0
11
116
0.95
0.00
1.1
1.5
—
—
—
0
0
10
98
1.02
0.00
3.9
4.1
—
—
—
0
0
27
268
1.01
0.00
12.4
11.7
—
—
—
0
0
19
189
1.01
0.00
1.2
1.3
—
—
—
0
0
11
109
1.01
0.00
1.1
1.5
—
—
—
0
0
87
867
1.00
0.00
4.6
4.5
—
—
—
0
0
10
95
1.05
0.00
1.5
1.2
—
—
—
0
0
5
51
0.98
0.00
3.2
2.5
—
—
—
0
0
0
7
0.00
0.00
0.0
5.7
—
0.40
—
0
7
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
6
66
0.91
-0.00
1.5
2.7
6.70
7.22
mmol/l
—
6
43
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
89
1.01
-0.00
1.0
1.5
—
—
—
0
0
5
54
0.93
-0.00
1.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
1.70
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_DUODENUM and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_DUODENUM 1.736 [1.49, 2.02] < 0.001
Birth year 0.994 [0.99, 1.0] 0.143

During the follow-up period (1.1.1998 — 31.12.2019), 518 out of 1933 females with CD2_BENIGN_DUODENUM died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_DUODENUM 2.001 [1.7, 2.36] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 669 out of 1893 males with CD2_BENIGN_DUODENUM died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_DUODENUM.

N-year risk Females Males
1 0.129% 0.405%
5 0.957% 2.134%
10 2.273% 5.405%
15 4.66% 10.356%
20 8.151% 16.828%

Relationships between endpoints

Index endpoint: CD2_BENIGN_DUODENUM – Benign neoplasm: Duodenum

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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