Other changes in lacrimal passages

H7_LACRIPAS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H04.6 Hospital discharge: ICD-9 — 3756 Hospital discharge: ICD-8 — 36805 Cause of death: ICD-10 — H04.6 Cause of death: ICD-9 — 3756 Cause of death: ICD-8 — 36805 2 out of 7 registries used, show all original rules.	52
4. Check minimum number of events None	52
5. Include endpoints None	52
6. Filter based on genotype QC (FinnGen only)	47

Control definitions (FinnGen only)

Control exclude: H7_LIDLACRIMALORBIT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: H04
Name in latin: Aliae morbositates apparati lacrimalis

NAME	H7_LACRIPAS
CONTROL_EXCLUDE	H7_LIDLACRIMALORBIT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H046
HD_ICD_9	3756
HD_ICD_8	36805
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H046
COD_ICD_9	3756
COD_ICD_8	36805
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other changes in lacrimal passages based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	334	214	120
Only index persons	291	191	100
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	-	54.59	38.23
Only index persons	49.58	54.40	40.38

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	47	40	7
Unadjusted period prevalence (%)	0.01	0.01	0.00
Median age at first event (years)	52.80	55.53	37.20

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
52: Matched controls
520

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H04.6

ICD-10 Finland

Other changes in lacrimal passages

+∞

52.1

H04.5

ICD-10 Finland

Stenosis and insufficiency of lacrimal passages

225.0

16.5

XCC00

NOMESCO Finland

Investigative irrigation of lacrimal passages

+∞

9.7

3756X

ICD-9 Finland

Disorders of lachrymal system, Other changes of lachrymal passages

+∞

7.5

H04.10

ICD-10 Finland

Dry eye syndrome

11.1

7.1

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

3.92

4.42

2.4

1.4

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

2.95

3.19

6.5

3.7

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

5.05

2.93

1.9

1.3

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

5.21

2.70

3.1

1.9

2.64

3.31

g/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

259

2.74

2.65

11.8

9.8

4.46

4.05

e9/l

0.43

226

(3030467) Casts [#/volume] in Urine by Automated count

124

2.53

2.63

5.5

3.0

0.12

0.19

e6/l

0.23

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.88

2.57

3.1

1.8

3.03

3.83

g/l

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.88

2.57

3.1

1.8

7.27

8.04

g/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.88

2.57

3.1

1.8

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

142

2.46

2.54

3.8

2.7

26.00

28.86

u/l

0.59

134

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

4.58

2.45

2.0

1.2

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

2.64

2.39

2.8

8.64

41.33

ng/l

1.50

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

2.52

2.28

2.1

1.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.82

2.22

1.6

1.7

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.52

2.20

4.5

2.5

1.44

0.63

e6/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

151

2.26

2.13

6.5

2.9

—

(3013707) Erythrocyte sedimentation rate by Westergren method

336

2.61

2.07

5.0

4.0

12.56

12.11

mm/h

0.10

302

(40758558) Short blood count panel - Blood

119

2.28

2.07

11.2

6.2

—

(3021601) Nitrite [Presence] in Urine by Test strip

208

2.21

2.01

9.1

5.1

0.00

estimate

—

(3018095) Leukocytes [#/volume] in Urine

154

2.20

2.01

7.3

4.2

24.24

55.30

e6/l

0.62

109

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.09

2.00

3.5

1.8

10.05

10.37

g/l

—

(36304419) Bacteria [Presence] in Urine

122

2.21

1.93

5.9

2.8

—

(3002256) Pathology report gross observation

2.59

1.91

1.3

1.1

—

(3000492) Spirometry study

2.89

1.91

1.3

1.5

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.89

1.91

2.8

2.3

6.28

5.66

kpa

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

271

2.27

1.88

3.5

2.7

41.38

45.73

u/l

0.18

252

(3035350) Ketones [Presence] in Urine by Test strip

212

2.14

1.87

6.8

3.6

0.00

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

213

2.13

1.84

6.8

3.6

0.00

estimate

—

(3022217) INR in Platelet poor plasma by Coagulation assay

186

2.09

1.81

12.8

10.4

1.37

1.24

inr

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.62

1.80

1.5

2.1

24.47

24.28

mmol/l

—

(3000991) Gas panel - Venous blood

3.20

1.79

2.7

3.0

—

(40760892) CBC W Ordered Manual Differential panel - Blood

199

2.03

1.68

8.5

5.3

—

(3002385) Erythrocyte distribution width [Ratio]

397

2.91

1.65

24.8

15.8

15.58

14.79

0.32

389

(3004588) Protein electrophoresis panel - Serum or Plasma

2.95

1.64

3.3

2.0

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

3.57

1.56

3.0

1.9

38.90

38.01

g/l

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

3.57

1.56

2.8

1.9

0.00

g/l

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

2.12

1.55

1.3

26.90

31.44

iu/ml

—

(3007164) IgA [Mass/volume] in Serum or Plasma

2.04

1.42

1.7

1.4

1.35

2.82

g/l

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.81

1.41

2.2

1.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.09

1.38

5.1

2.5

0.86

2.60

e6/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.59

1.36

1.6

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

230

1.86

1.32

6.3

6.4

10.65

9.41

umol/l

0.45

214

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.03

1.29

2.0

1.9

—

(3019060) Gas panel - Arterial blood

2.58

1.28

3.5

4.0

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

397

2.37

1.26

6.4

5.0

40.00

39.13

mmol/mol

0.23

366

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.80

1.24

1.4

1.0

—

(3002582) Erythrocytes [#/volume] in Urine

140

1.84

1.24

6.3

3.2

16.64

20.56

e6/l

0.20

103

(3024354) Oxygen [Partial pressure] in Venous blood

2.47

1.22

3.3

2.3

4.43

4.28

kpa

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

132

1.84

1.21

3.6

2.1

87.20

137.79

u/l

0.81

123

(3045414) Leukocytes [Presence] in Urine

2.65

1.18

2.4

1.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

173

1.72

1.06

2.3

1.8

107.19

100.88

pmol/l

—

(36660697) Celiac disease serology panel - Serum

2.09

1.01

1.4

1.1

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.79

0.98

2.0

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

408

2.10

0.98

19.1

12.8

84.06

82.30

ml/min/173m2

0.21

323

(3026008) Bacteria identified in Urine by Culture

160

1.65

0.91

5.4

2.9

—

(3012516) Albumin [Mass/volume] in Urine

1.75

0.91

4.5

2.8

5248.00

45.01

mg/l

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.93

0.91

1.8

2.4

2.60

2.52

g/l

—

(3000494) Fungus identified in Specimen by Culture

1.93

0.91

1.4

1.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

311

1.66

0.83

7.2

4.3

—

(40768804) Tissue Pathology biopsy report

182

1.59

0.83

2.0

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.29

0.78

3.0

2.7

1.06

1.21

mmol/l

—

(3023368) Bacteria identified in Blood by Culture

103

1.64

0.76

9.3

3.9

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.86

0.75

1.3

1.4

—

(3042936) Bacteria identified in Isolate by Culture

1.79

0.75

2.3

2.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.67

0.75

1.8

1.9

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

205

1.54

0.74

5.7

5.5

1.21

1.23

mmol/l

0.98

171

(3001122) Ferritin [Mass/volume] in Serum or Plasma

196

1.53

0.73

3.6

2.6

195.81

74.60

ug/l

0.61

180

(3044889) 12 lead EKG panel

306

1.57

0.72

4.9

3.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

105

1.60

0.70

4.6

3.5

3.84

7.18

mg/mmol

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

1.59

0.63

1.2

1.3

1.24

11.31

u/ml

—

(4200892) Spirometry reversibility

1.74

0.63

1.4

1.3

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.56

0.53

4.7

3.7

102.17

102.65

mmol/l

—

(3026493) Urate [Moles/volume] in Serum or Plasma

112

1.48

0.52

2.7

2.5

303.27

3800.37

umol/l

0.50

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

160

1.41

0.49

7.8

3.7

13.22

58.44

ng/l

0.99

109

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

289

1.39

0.46

3.9

3.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.39

0.43

1.5

1.7

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.41

0.0

1.7

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.40

0.0

1.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.47

0.40

2.2

1.9

—

(40761536) Microorganisms panel - Urine sediment

1.43

0.39

7.4

3.5

—

(3022145) Colonoscopy Study observation

1.45

0.36

1.3

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.38

0.35

3.0

1.4

—

(3029937) Albumin [Presence] in Urine by Test strip

111

1.36

0.34

9.1

3.9

0.00

estimate

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

171

1.28

0.29

7.9

3.4

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.28

0.23

1.2

1.6

—

(3027801) Oxygen [Partial pressure] in Arterial blood

1.28

0.23

4.8

4.0

9.06

12.88

kpa

—

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

1.28

0.23

4.8

4.0

5.32

5.25

kpa

—

(3044640) Blood type and Crossmatch panel - Blood

127

1.25

0.23

4.0

1.8

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.21

0.0

2.9

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

4.50

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

3.5

—

26.61

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.21

0.0

1.5

—

(3037756) Immunofixation for Serum or Plasma

0.00

0.21

0.0

1.4

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

2.6

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.21

0.0

1.1

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

0.00

0.21

0.0

3.8

—

25.42

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

1.26

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.21

0.0

1.5

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.21

0.0

2.8

—

8.28

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.21

0.0

3.5

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

216

1.21

0.21

3.0

2.3

—

(3013512) EKG study

129

1.23

0.20

5.7

3.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.15

0.18

2.6

2.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.21

0.18

2.5

1.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.24

0.15

3.8

1.9

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.12

0.10

12.2

4.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.12

0.10

3.2

1.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.10

0.10

19.0

7.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.17

0.10

1.5

1.4

—

(1761868) Lipid panel - Serum or Plasma

154

0.88

0.09

2.6

2.9

—

(40768797) Stomach Pathology biopsy report

1.08

0.09

2.3

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.08

0.09

1.8

—

(3048689) Calprotectin [Mass/mass] in Stool

0.83

0.09

4.6

1.5

54.60

147.85

ug/g

—

(3041096) Erythrocytes [Presence] in Urine by Automated

133

1.07

0.02

5.4

3.2

—

(3003694) ABO and Rh group [Type] in Blood

137

0.93

0.02

1.3

1.5

—

(3021960) Folate [Moles/volume] in Serum or Plasma

108

1.02

0.00

2.0

1.5

12.46

24.02

nmol/l

3.60

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

1.7

—

26.04

—

(4281824) Cell count and differential, peritoneal fluid

0.00

0.0

1.0

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

2.6

—

(3000012) Reticulocyte production index

0.00

0.0

2.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

2.6

—

3.91

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

0.0

1.3

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

1.7

—

31.33

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.3

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

2.6

—

108.57

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

0.0

1.5

—

7.50

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(3023410) Appearance of Cerebral spinal fluid

0.00

0.0

1.3

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.3

—

(3016018) Differential panel - Cerebral spinal fluid

0.00

0.0

1.0

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

1.1

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

0.96

-0.00

2.9

1.6

1484.00

1156.42

nmol/l

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.6

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

2.0

—

6.18

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

14.08

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3005082) Progesterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

40.68

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

1.8

—

(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum

0.00

-0.00

0.0

1.4

—

17.42

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_LACRIPAS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H7_LACRIPAS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: H7_LACRIPAS – Other changes in lacrimal passages

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other changes in lacrimal passages

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints