Other and unspecified degenerative diseases of nervous system

G6_DEGENOTH

Lewy body dementia: A progressive form of dementia characterized by the presence of protein deposits called Lewy bodies in the midbrain and cerebral cortex, and loss of cholinergic and dopaminergic neurons. The signs and symptoms overlap with Alzheimer and Parkinson disease.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G31.8, G31.9, G32*
  • Hospital discharge: ICD-9 331[8-9]
  • Hospital discharge: ICD-8 32303
  • Cause of death: ICD-10 G31.8, G31.9, G32*
  • Cause of death: ICD-9 331[8-9]
  • Cause of death: ICD-8 32303

2 out of 7 registries used, show all original rules.

971

4. Check minimum number of events

None

971

5. Include endpoints

None

971

6. Filter based on genotype QC (FinnGen only)

944

Control definitions (FinnGen only)

Control exclude
G6_NEURODEG

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10790 5168 5413
Only index persons 7351 3692 3659
Unadjusted period prevalence (%)
Whole population 0.15 0.15 0.15
Only index persons 0.14 0.14 0.14
Median age at first event (years)
Whole population 74.25 75.65 72.93
Only index persons 74.27 75.65 72.88

-FinnGen-

Key figures

All Female Male
Number of individuals 944 382 562
Unadjusted period prevalence (%) 0.21 0.14 0.26
Median age at first event (years) 73.77 74.47 73.29

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
971
Matched controls
9710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G31.9
ICD-10 Finland
Degenerative disease of nervous system, unspecified
2336.4
307.7
315
*
G31.8
ICD-10 Finland
Other specified degenerative diseases of nervous system
3836.9
307.7
597
*
N06DA03
ATC
rivastigmine; oral, transdermal
32.0
307.7
299
133
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
15.9
274.3
265
224
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
8.0
183.8
312
544
G30.8
ICD-10 Finland
Other Alzheimer disease
61.8
170.1
95
17
N05AH04
ATC
quetiapine; oral
6.7
164.4
343
732
307
Kela drug reimbursment
Tacrine, donepezil, rivastigmine, galantamine and other major and expensive drugs used to treat Alzheimer's disease
26.5
160.2
113
48
N05AX08
ATC
risperidone; systemic
8.4
154.1
231
346
N06DX01
ATC
memantine; oral
10.6
153.9
186
213
F03
ICD-10 Finland
Unspecified dementia
9.6
145.0
190
241
G30.9
ICD-10 Finland
Alzheimer disease, unspecified
60.9
121.5
68
12
G30.1
ICD-10 Finland
Alzheimer disease with late onset
14.2
119.9
114
90
TAB00
NOMESCO Finland
Lumbar puncture
10.4
113.4
134
147
N06DA02
ATC
donepezil; oral
9.2
108.9
142
177
G20
ICD-10 Finland
Parkinson disease
8.6
107.1
149
201
P20
ICPC
Memory disturbance
4.5
97.4
317
946
XA800
NOMESCO Finland
Neuropsychological investigation
10.2
90.3
107
117
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
8.0
89.7
130
183
N05AH03
ATC
olanzapine; systemic
7.8
73.8
108
153
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.8
64.2
163
391
A28
ICPC
Limited function/disability NOS
3.3
63.7
347
1411
N99
ICPC
Neurological disease other
16.1
63.6
55
36
P70
ICPC
Dementia
10.0
63.5
75
81
G31.0
ICD-10 Finland
Circumscribed brain atrophy
220.5
60.8
62
*
N87
ICPC
Parkinsonism
9.0
54.2
69
82
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.6
52.7
140
346
AA1AD
NOMESCO Finland
CT of head and brain
2.8
51.7
425
2123
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
13.1
51.5
50
40
R41.3
ICD-10 Finland
Other amnesia
6.8
50.7
83
132
R41.0
ICD-10 Finland
Disorientation, unspecified
6.1
50.1
91
161
F06.7
ICD-10 Finland
Mild cognitive disorder
6.4
49.3
86
146
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
46.7
329
1503
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.7
45.6
115
272
R53
ICD-10 Finland
Malaise and fatigue
2.8
45.3
330
1529
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
10.5
44.6
50
50
N03AG01
ATC
valproic acid; systemic, rectal
5.2
44.4
97
203
N05BA04
ATC
oxazepam; oral
2.7
43.2
332
1575
R44.1
ICD-10 Finland
Visual hallucinations
16.2
41.9
36
23
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.5
40.1
428
2355
F05.9
ICD-10 Finland
Delirium, unspecified
6.3
39.8
69
116
N28
ICPC
Limited function/disability (N)
8.9
39.4
50
59
N29
ICPC
Neurological sympt/complt other
8.0
39.0
54
71
N03AE01
ATC
clonazepam; systemic
4.2
33.7
96
248
G30.0
ICD-10 Finland
Alzheimer disease with early onset
+∞
31.4
30
*
SPAT1216
SPAT
Assessment of functional ability
2.5
31.2
250
1184
L28
ICPC
Limited function/disability (L)
2.4
31.0
275
1364
N05BA06
ATC
lorazepam; systemic, sublingual
3.9
30.1
96
269
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.0
29.8
91
247
N05AD01
ATC
haloperidol; systemic
5.0
29.4
65
137
F0280, G318,
ICD-10 Finland
+∞
28.3
27
*
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
10.0
27.8
32
33
N06AX11
ATC
mirtazapine; oral
2.2
27.7
362
2093
F05.1
ICD-10 Finland
Delirium superimposed on dementia
26.3
27.6
38
15
SPAT1053
SPAT
Memory test
2.4
27.6
234
1130
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
5.4
27.2
55
107
3319X
ICD-9 Finland
Other cerebral degenerations, Cerebral degeneration, unspecified
+∞
26.2
25
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
3.4
25.6
101
325
N05AX12
ATC
aripiprazole; systemic
7.4
24.7
36
50
F29
ICD-10 Finland
Unspecified nonorganic psychosis
6.0
24.6
44
76
N06AB10
ATC
escitalopram; oral
2.5
24.4
179
805
I95.1
ICD-10 Finland
Orthostatic hypotension
3.5
24.2
87
264
Z2445
NOMESCO Finland
Psychologist
5.4
24.1
48
92
F00.10*G30.1
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
7.0
23.9
37
55
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.7
23.1
141
580
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.9
23.0
119
448
R25.1
ICD-10 Finland
Tremor, unspecified
4.6
22.4
54
122
R27.0
ICD-10 Finland
Ataxia, unspecified
18.5
22.3
34
19
R1250
NOMESCO Finland
Evaluation of functional capability
5.8
22.3
41
73
F02.80
ICD-10 Finland
Dementia in another specified disease that is classified elsewhere without additional symptoms
+∞
22.0
21
*
A06AD11
ATC
lactulose; oral
2.2
21.9
238
1263
G31.2
ICD-10 Finland
Degeneration of nervous system due to alcohol
51.2
21.2
25
5
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
21.1
98
347
SPAT1245
SPAT
Provision of support and information to patient’s family members
3.4
21.0
80
252
N05AD03
ATC
melperone; systemic
6.1
20.1
35
59
F0289, G318,
ICD-10 Finland
+∞
19.9
19
*
F02.09*G31.0
ICD-10 Finland
Dementia in Pick's disease without information on additional symptoms
+∞
19.9
19
*
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
41.0
19.6
24
6
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
19.5
354
2242
N06AB04
ATC
citalopram; systemic
2.1
19.4
221
1188
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.0
19.0
56
148
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
5.0
18.6
40
82
N06AX26
ATC
vortioxetine; oral
3.5
18.5
66
199
M03BX01
ATC
baclofen; systemic
5.5
18.4
36
68
A04
ICPC
Weakness/tiredness general
2.2
18.3
177
890
H02AA02
ATC
fludrocortisone; oral
7.3
18.3
27
38
IGY02
NOMESCO Finland
Psychiatric monitoring contact
6.8
17.9
28
42
S06.0
ICD-10 Finland
Concussion
2.5
17.9
126
552
N19
ICPC
Speech disorder
5.8
17.8
33
59
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.4
17.8
45
106
F0029, G308,
ICD-10 Finland
+∞
17.8
17
*
G31.1
ICD-10 Finland
Senile degeneration of brain, not elsewhere classified
183.2
17.6
18
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.7
17.5
103
414
N06DA04
ATC
galantamine; oral
5.0
17.2
37
76
SPAT1234
SPAT
Support of social functional capacity
2.9
16.9
84
309
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
16.8
196
1057
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.2
16.8
67
217
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
3.1
16.4
71
241
G23.8
ICD-10 Finland
Other specified degenerative diseases of basal ganglia
40.8
16.4
20
5
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.0
16.3
46
118
N04BD01
ATC
selegiline; oral
5.0
16.2
35
72
SPAT1229
SPAT
Assessment of need for aid
2.5
16.0
112
489
F0282, G318,
ICD-10 Finland
+∞
15.7
15
*
F0019, G301,
ICD-10 Finland
+∞
15.7
15
*
G04BD12
ATC
mirabegron; oral
2.1
15.6
159
814
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
5.6
15.3
29
53
K59.09
ICD-10 Finland
Constipation, unspecified
2.5
15.0
96
401
F22.0
ICD-10 Finland
Delusional disorder
6.6
15.0
24
37
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
5.6
14.8
28
51
S01.0
ICD-10 Finland
Open wound of scalp
2.4
14.8
107
474
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
14.5
68
242
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
6.3
14.2
24
39
N03AX14
ATC
levetiracetam; systemic
4.1
14.2
39
98
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
5.2
14.2
29
57
R42
ICD-10 Finland
Dizziness and giddiness
1.8
14.1
260
1626
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
13.6
194
1117
3318X
ICD-9 Finland
Other cerebral degenerations, Other cerebral degeneration
+∞
13.6
13
*
N02AA05
ATC
oxycodone; systemic
1.8
13.5
235
1443
R4130
NOMESCO Finland
Speech therapy
4.0
13.3
38
98
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
13.1
84
352
S72.0
ICD-10 Finland
Fracture of neck of femur
2.6
13.0
75
298
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
3.8
12.9
39
105
D21
ICPC
Swallowing problem
4.5
12.9
31
70
N30.0
ICD-10 Finland
Acute cystitis
2.0
12.8
161
888
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
12.7
105
492
Z02.4
ICD-10 Finland
Examination for driving licence
0.5
12.7
129
2302
WYA20
NOMESCO Finland
Home visit
4.2
12.6
33
80
F02.8
ICD-10 Finland
Dementia in other specified diseases classified elsewhere
+∞
12.5
12
*
AA5DR
NOMESCO Finland
Brain metabolism PET with CT
131.6
12.5
13
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
5.7
12.5
23
41
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.9
12.3
57
202
R35
ICD-10 Finland
Polyuria
2.4
12.2
91
408
F06.0
ICD-10 Finland
Organic hallucinosis
18.3
12.1
18
10
G11.9
ICD-10 Finland
Hereditary ataxia, unspecified
18.3
12.1
18
10
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.9
11.7
166
951
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.7
11.7
62
236
F009, G309,
ICD-10 Finland
+∞
11.5
11
*
G32.0*E53.8
ICD-10 Finland
Subacute combined degeneration of the spinal cord in case of vitamin B12 deficiency
+∞
11.5
11
*
Z75.5
ICD-10 Finland
Holiday relief care
5.5
11.4
22
41
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
11.3
11.1
20
18
SPAT1231
SPAT
Assessment of adjustments needed in living environment
3.5
11.1
38
112
F00.00*G30.0
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, presenile onset without additional symptoms
43.8
10.9
13
*
N06AB06
ATC
sertraline; oral
2.3
10.9
86
395
R5110, ,
SPAT
2.4
10.9
80
357
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.5
10.8
37
109
IBZ07
NOMESCO Finland
Neurological assessment in psychiatry
28.4
10.7
14
5
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
10.2
10.5
20
20
F02.84
ICD-10 Finland
Dementia in another specified disease that is classified elsewhere as other mixed symptoms of mixed type
+∞
10.4
10
*
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
7.8
10.4
23
30
SPAT1254
SPAT
Administration of medicine
1.8
10.4
169
1009
N05BA01
ATC
diazepam; systemic, rectal
1.9
10.3
137
768
NFB20
NOMESCO Finland
Primary partial prosthetic replacement of hip joint using cement, other or unspecified
2.9
10.0
48
173
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
9.9
170
1031
N06AX16
ATC
venlafaxine; oral
2.1
9.8
103
530
N80
ICPC
Head injury other
3.9
9.8
29
77
N05BE01
ATC
buspirone; oral
3.5
9.7
33
97
N03AX09
ATC
lamotrigine; oral
3.4
9.7
34
102
N04AA02
ATC
biperiden; systemic
4.4
9.6
24
56
N04BC04
ATC
ropinirole; oral
5.1
9.6
20
40
R55
ICD-10 Finland
Syncope and collapse
1.9
9.5
134
764
N05AF03
ATC
chlorprothixene; systemic
4.2
9.5
25
61
F02.82
ICD-10 Finland
Dementia in other specified disease that is classified elsewhere other symptoms, mainly hallucinations
101.0
9.4
10
*
G71.3
ICD-10 Finland
Mitochondrial myopathy, not elsewhere classified
+∞
9.4
9
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.7
9.3
21
45
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.7
9.0
47
178
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
4.3
9.0
23
55
F02.89
ICD-10 Finland
Dementia in another specified disease that is classified elsewhere without information of additional symptoms
24.3
8.9
12
5
G30
ICD-10 Finland
Alzheimer disease
12.7
8.9
15
12
A29
ICPC
General symptom/complaint other
1.8
8.9
136
796
G72.8
ICD-10 Finland
Other specified myopathies
3.6
8.8
29
83
G93.4
ICD-10 Finland
Encephalopathy, unspecified
14.2
8.7
14
10
P29
ICPC
Psychological sympt/compl other
2.8
8.6
41
148
N04BC05
ATC
pramipexole; oral
2.0
8.5
89
457
N05AB03
ATC
perphenazine; systemic, rectal
3.1
8.5
35
116
G11.2
ICD-10 Finland
Late-onset cerebellar ataxia
27.8
8.5
11
*
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
3.7
8.5
26
71
R47.1
ICD-10 Finland
Dysarthria and anarthria
4.2
8.5
22
53
AXX01, ,
SPAT
2.8
8.5
41
149
W19
ICD-10 Finland
Unspecified fall
1.9
8.4
105
575
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
8.4
80
398
F028, G318,
ICD-10 Finland
+∞
8.3
8
*
XF606
NOMESCO Finland
Ortostatic test
7.2
8.3
19
27
SPAT1360
SPAT
Extensive global examination
2.2
8.3
70
332
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.8
8.1
123
716
R44.3
ICD-10 Finland
Hallucinations, unspecified
9.0
8.1
16
18
N05AA02
ATC
levomepromazine; systemic
2.7
8.0
42
160
F00
ICD-10 Finland
Dementia in Alzheimer disease
13.2
7.9
13
10
F06.9
ICD-10 Finland
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
13.2
7.9
13
10
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
15.2
7.7
12
8
N06AX21
ATC
duloxetine; oral
1.9
7.6
92
498
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
7.5
96
529
N05BA12
ATC
alprazolam; oral
1.9
7.5
92
501
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
3.6
7.5
24
68
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.2
7.4
28
88
G32
ICD-10 Finland
Other degenerative disorders of nervous system in diseases classified elsewhere
80.7
7.4
8
*
U04
ICPC
Incontinence urine
2.2
7.4
64
306
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
7.4
40
155
R26.0
ICD-10 Finland
Ataxic gait
11.0
7.3
13
12
G32.8
ICD-10 Finland
Other specified degenerative disorders of nervous system in diseases classified elsewhere
+∞
7.3
7
*
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.8
7.3
114
671
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.6
7.3
42
168
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.1
7.2
30
100
N04BD02
ATC
rasagiline; oral
5.9
7.2
19
33
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
15.9
7.2
11
7
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.6
7.2
23
65
N02BE01
ATC
paracetamol; systemic, rectal
1.6
7.2
802
7255
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.1
174
1157
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
7.0
52
234
L89
ICD-10 Finland
Decubitus ulcer and pressure area
3.1
7.0
29
97
S01.8
ICD-10 Finland
Open wound of other parts of head
3.7
6.9
21
57
N05AN01
ATC
lithium; oral
3.7
6.9
21
57
N05AH02
ATC
clozapine; systemic
5.9
6.9
18
31
F00.10
ICD-10 Finland
Primary degenerative dementia of the Alzheimer's type, senile onset without additional symptoms
13.9
6.9
11
8
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
5.7
6.8
18
32
F05.8
ICD-10 Finland
Other delirium
5.7
6.8
18
32
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
6.8
131
818
IGP01
NOMESCO Finland
Psychiatric family contact
16.8
6.8
10
6
ZY000
NOMESCO Finland
Hospital inpatient
6.5
6.7
16
25
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
6.6
163
1083
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
6.3
119
737
SPAT1167
SPAT
Insertion of urinary catheter
2.3
6.3
48
218
F0284, G318,
ICD-10 Finland
+∞
6.3
6
*
F0014, G301,
ICD-10 Finland
+∞
6.3
6
*
Z31.5
ICD-10 Finland
Genetic counselling
2.8
6.2
31
115
S00.0
ICD-10 Finland
Superficial injury of scalp
2.8
6.2
29
104
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
3.2
6.2
24
77
N05CF01
ATC
zopiclone; oral
1.4
6.2
320
2480
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
3.2
6.2
23
72
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
6.1
6.0
15
25
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.9
6.0
17
44
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.9
6.0
17
44

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
94
38
27.28
135.36
1.1
1.0
290.39
242.26
ng/l
0.59
79
19
94
38
27.28
135.36
1.1
1.0
714.64
732.95
ng/l
0.07
76
20
111
112
11.06
99.39
1.3
1.2
—
—
—
0
0
113
121
10.44
96.96
1.2
1.2
3.88
3.88
mmol/l
0.01
108
113
106
131
8.96
81.30
1.3
1.3
3.25
71.75
e6/l
0.92
77
107
105
131
8.87
79.90
1.3
1.3
250.10
963.84
e6/l
0.42
81
109
56
56
10.55
49.97
1.4
1.2
—
—
—
0
0
49
51
10.07
42.43
1.3
1.0
—
—
—
0
0
328
1723
2.36
32.72
1.9
1.8
1102.70
1179.62
nmol/l
0.73
257
1286
47
79
6.20
27.06
5.6
4.1
350.99
345.57
umol/l
0.08
38
69
519
3468
2.07
26.74
2.4
2.1
90.68
93.24
pmol/l
0.60
287
1773
400
2447
2.08
26.03
2.8
2.1
264.72
247.52
u/l
0.12
379
2292
339
2073
1.98
21.09
1.7
1.6
20.45
20.06
nmol/l
0.18
297
1720
498
3702
1.71
14.80
4.9
6.2
1.22
1.21
mmol/l
3.13
455
3351
535
4074
1.70
14.38
5.8
7.1
1.22
1.21
mmol/l
2.64
475
3463
379
2635
1.72
14.26
4.2
3.5
—
—
—
0
0
380
2682
1.68
13.29
2.5
3.6
2.35
2.35
mmol/l
0.26
314
2310
625
5069
1.65
12.25
7.0
5.0
42.11
1746.45
e6/l
—
9
88
352
2494
1.65
11.79
4.6
4.5
—
—
—
0
0
21
37
5.78
11.51
1.1
1.2
139.62
133.41
nmol/l
0.19
21
37
52
184
2.93
11.22
2.4
2.8
26.95
36.03
umol/l
2.35
45
161
393
2926
1.58
10.39
2.3
2.2
76.19
79.23
nmol/l
1.20
332
2533
457
3531
1.56
10.20
4.1
5.0
34.75
34.46
g/l
0.52
415
3271
330
2406
1.56
9.33
3.5
4.0
7.40
7.40
ph
0.25
41
448
20
27
7.54
8.96
1.8
1.5
—
—
—
0
0
614
5165
1.51
8.58
5.9
4.7
—
—
—
0
0
124
2015
0.56
8.40
3.1
3.3
—
—
—
0
0
255
1800
1.57
8.12
1.7
1.8
456.07
8014130.92
pmol/l
0.80
210
1460
229
1588
1.58
7.85
2.8
3.2
2.46
2.46
mmol/l
0.04
200
1370
52
224
2.40
7.67
1.2
1.4
—
—
—
0
0
234
1690
1.51
6.54
4.6
3.9
—
—
—
0
0
288
2180
1.46
6.34
2.1
2.2
2.71
3.14
mg/l
2.47
235
1821
596
5163
1.40
5.93
3.9
3.7
15.40
15.06
pmol/l
2.19
531
4554
12
17
7.13
5.45
1.1
1.2
—
—
—
0
0
16
36
4.50
5.07
1.1
1.1
—
—
—
0
0
200
1470
1.45
5.00
3.4
2.9
1.26
1.32
e6/l
0.06
105
882
538
4660
1.35
4.91
6.4
5.1
6.83
6.84
mmol/l
0.07
508
4396
179
1295
1.47
4.85
1.3
1.2
0.91
1.61
u/ml
1.22
40
319
189
1392
1.44
4.66
3.6
3.2
2.25
2.06
e6/l
0.13
94
809
486
4203
1.31
4.23
3.9
3.2
51.21
56.12
u/l
0.58
437
3826
119
817
1.52
4.16
4.0
4.6
—
—
—
0
0
278
2235
1.34
4.00
3.9
3.4
—
—
—
0
0
175
1309
1.41
3.93
2.8
3.2
0.81
0.81
mmol/l
0.32
159
1221
204
1571
1.38
3.86
5.4
4.5
1.02
1.02
kg/l
0.02
35
234
18
67
2.72
3.67
2.7
2.9
—
—
—
0
0
339
2833
1.30
3.65
4.3
3.8
5.87
5.87
ph
0.00
15
135
103
706
1.51
3.64
1.4
1.5
—
—
—
0
0
95
645
1.52
3.51
1.8
2.1
428.90
380.95
nmol/l
1.03
89
579
55
328
1.72
3.44
2.1
2.4
357.72
561.79
ug/l
0.44
49
311
237
2905
0.76
3.42
2.0
2.3
—
—
—
0
0
412
3556
1.28
3.39
4.7
4.1
0.06
0.00
estimate
0.48
54
736
9
19
4.77
3.24
1.1
1.1
—
—
—
0
0
639
5841
1.27
3.18
6.7
7.8
77.96
81.58
u/l
1.58
585
5445
469
4143
1.26
3.08
18.1
19.1
1.31
1.39
inr
0.76
102
1162
6
8
7.54
3.06
1.2
1.0
—
—
—
0
0
412
3595
1.25
2.99
4.8
4.1
0.00
0.00
estimate
-0.00
52
652
306
2582
1.27
2.95
4.0
3.5
68.08
89.18
e6/l
0.29
217
2044
11
291
0.37
2.92
1.3
1.4
—
—
—
0
0
68
1002
0.65
2.90
1.1
1.3
15.97
13.26
u/ml
0.09
19
363
693
6428
1.27
2.90
5.3
4.6
1.88
2.24
mu/l
1.17
621
5708
92
648
1.46
2.88
1.5
2.7
—
—
—
0
0
282
2363
1.27
2.86
4.0
3.4
0.38
0.55
e6/l
1.34
200
1848
107
779
1.42
2.81
1.4
3.0
65.91
65.86
g/l
0.02
95
704
207
1671
1.30
2.81
4.1
4.1
252.18
263.12
ng/l
0.03
188
1453
637
6830
0.80
2.61
4.3
4.7
4.39
4.42
mmol/l
0.25
560
6160
142
1099
1.34
2.59
1.6
2.4
1.86
1.79
%
0.33
125
965
105
778
1.39
2.51
2.1
2.2
0.20
0.20
g/l
0.07
93
721
632
6764
0.81
2.44
4.3
4.7
1.45
1.43
mmol/l
0.72
559
6042
401
3547
1.22
2.43
6.3
5.6
0.00
0.00
estimate
-0.00
53
673
283
2416
1.24
2.40
2.6
2.6
52.89
92.89
u/l
0.64
255
2227
169
2077
0.77
2.38
2.4
2.9
3111.99
8112.82
umol/l
0.99
134
1772
12
46
2.63
2.36
5.8
17.6
—
—
—
0
0
376
3324
1.21
2.25
5.3
5.7
0.59
0.63
%
0.92
338
3064
112
855
1.35
2.25
3.2
3.4
2.19
2.14
mmol/l
0.05
100
684
661
7021
0.82
2.24
5.0
5.4
2.53
2.55
mmol/l
0.28
580
6289
154
1900
0.77
2.23
1.4
1.6
1.17
1.33
mmol/l
2.79
137
1549
112
857
1.35
2.22
2.5
3.0
148.69
263.34
ng/l
5.38
102
792
368
3252
1.21
2.20
4.4
4.2
26.92
53.81
ng/l
2.09
291
2549
585
5405
1.21
2.17
4.1
4.1
12.70
14.63
mm/h
2.37
523
4921
57
817
0.68
2.15
1.4
1.3
—
—
—
0
0
331
2901
1.21
2.14
4.6
3.9
66.18
122.74
e6/l
1.21
228
2165
65
456
1.46
2.13
1.2
1.2
—
—
—
0
0
411
3683
1.20
2.10
5.4
5.6
1.66
1.86
e9/l
2.69
335
3208
101
768
1.35
2.09
3.4
7.1
1.47
1.43
mmol/l
0.18
95
750
114
884
1.33
2.07
3.0
3.5
—
7.39
—
0
8
79
579
1.40
2.05
3.5
4.1
7.43
7.39
ph
1.88
12
70
402
3604
1.20
2.02
5.3
5.5
0.61
0.62
e9/l
0.20
326
3049
5
147
0.34
2.01
1.2
1.3
—
—
—
0
0
403
3615
1.20
2.01
5.3
5.5
0.04
0.04
e9/l
0.51
329
3065
39
593
0.64
1.98
1.6
1.5
—
—
—
0
0
6
16
3.77
1.93
1.5
1.0
1348.50
1675.75
miu/ml
—
6
16
40
259
1.57
1.92
3.2
3.7
—
—
—
0
0
339
3004
1.20
1.92
2.5
2.8
139.32
157.36
ug/l
0.70
309
2691
79
587
1.38
1.90
3.5
4.1
5.16
5.15
kpa
0.06
74
560
11
238
0.46
1.89
1.4
1.2
—
—
—
0
0
414
3739
1.19
1.88
5.5
5.6
0.18
0.20
e9/l
0.99
342
3227
7
22
3.20
1.88
2.4
1.5
65.83
57.82
ug/l
—
7
22
40
261
1.56
1.87
1.1
1.1
—
103.88
titre
—
0
8
382
3430
1.19
1.85
5.4
6.1
8.87
8.96
%
0.25
343
3169
618
6558
0.84
1.82
3.8
4.2
1.19
1.27
mmol/l
2.97
542
5811
381
3426
1.18
1.81
5.4
5.8
60.14
58.58
%
1.83
342
3176
147
1202
1.26
1.81
1.5
1.4
2.69
2.64
g/l
0.11
73
676
50
347
1.46
1.77
1.6
2.7
9.47
10.79
g/l
1.27
42
308
65
474
1.40
1.77
2.5
2.6
—
—
—
0
0
379
3414
1.18
1.75
5.3
5.7
2.81
2.89
%
0.29
340
3151
16
82
1.97
1.70
1.3
1.4
271.00
276.39
mosm/kgh2o
—
10
57
26
416
0.61
1.68
2.3
1.8
4.17
2.40
ug/l
0.22
20
354
6
147
0.40
1.65
1.8
3.6
2.17
0.87
%
—
6
126
258
2262
1.19
1.61
2.8
3.2
29.77
35.57
u/l
2.66
239
2151
10
43
2.34
1.59
1.2
1.8
47.65
35.27
%
—
10
43
103
820
1.29
1.59
1.6
2.5
70.30
67.03
e9/l
0.36
78
641
384
3489
1.17
1.55
5.4
6.0
24.39
25.91
%
2.18
343
3226
166
1948
0.82
1.52
3.4
3.3
0.67
0.81
ug/l
1.54
125
1397
448
4128
1.16
1.49
4.4
6.4
11.50
12.61
umol/l
1.94
411
3920
659
6903
0.86
1.41
5.1
5.1
6.17
6.12
mmol/l
0.42
583
6126
84
1053
0.78
1.40
1.2
1.3
29.19
41.56
iu/ml
0.53
23
328
10
46
2.19
1.40
4.0
1.4
—
—
—
0
0
457
4236
1.15
1.37
7.2
8.8
4.64
4.29
e9/l
1.69
383
3649
41
291
1.43
1.34
1.7
2.6
37.29
36.89
g/l
0.16
33
253
68
530
1.30
1.26
2.3
2.7
10.28
10.96
g/l
0.63
59
478
78
620
1.28
1.25
3.9
5.1
—
—
—
0
0
11
203
0.54
1.25
2.2
1.6
11615.00
16527.07
e6/l
0.45
11
148
15
85
1.78
1.23
1.5
1.1
31.33
38.11
iu/ml
—
6
18
11
201
0.54
1.22
1.7
1.5
—
—
—
0
0
18
286
0.62
1.19
1.4
3.1
42.00
77.10
u/ml
0.59
18
278
86
697
1.26
1.19
4.5
3.5
—
—
—
0
0
293
3216
0.87
1.17
11.1
10.2
0.00
0.00
e9/l
1.16
220
2600
24
356
0.67
1.17
2.2
3.4
16.47
11590.44
u/ml
0.88
19
309
17
272
0.62
1.16
1.2
1.3
—
—
—
0
0
32
224
1.44
1.15
1.9
1.5
222.29
268.82
ug/g
0.58
17
133
0
35
0.00
1.15
0.0
1.7
—
0.95
—
0
35
49
640
0.75
1.14
3.4
4.2
0.93
0.91
%
0.03
15
252
43
571
0.74
1.13
3.6
4.1
0.92
0.59
%
0.41
13
214
241
2671
0.87
1.10
3.8
3.9
6.92
9.47
mg/mmol
0.67
146
1718
8
41
1.96
1.09
2.4
2.1
257.75
707.06
e6/l
—
8
36
26
177
1.48
1.08
1.3
1.2
—
—
—
0
0
110
931
1.20
1.04
1.9
1.8
—
—
—
0
0
79
958
0.81
1.03
3.3
4.0
34.94
27.58
ug/l
0.10
67
812
43
562
0.75
1.03
3.7
4.3
0.00
0.09
%
—
10
179
64
513
1.27
1.00
4.3
3.2
—
—
—
0
0
201
1796
1.15
0.99
3.3
3.2
559.54
545.79
mosm/kgh2o
0.41
165
1535
733
7089
1.14
0.98
21.7
17.6
27.22
27.75
mg/l
0.17
643
5805
87
724
1.22
0.98
1.9
2.4
30.19
37.14
u/l
0.74
70
611
7
36
1.95
0.97
2.9
1.3
—
—
—
0
0
9
50
1.81
0.96
2.2
1.3
—
—
—
0
0
122
1052
1.18
0.95
4.0
7.6
5.00
5.08
kpa
0.43
115
1002
0
32
0.00
0.95
0.0
1.0
—
—
—
0
0
9
51
1.77
0.94
1.0
1.0
—
—
—
0
0
122
1053
1.18
0.94
4.0
7.6
11.35
11.97
kpa
0.60
113
1005
47
598
0.78
0.94
3.5
4.2
0.15
0.10
%
0.21
13
211
6
27
2.23
0.93
1.0
1.4
—
—
—
0
0
116
999
1.18
0.92
1.4
1.2
—
—
—
0
0
89
749
1.21
0.91
4.0
8.0
—
—
—
0
0
229
2514
0.88
0.90
3.2
3.3
739.76
292.13
mg/l
0.43
137
1655
6
29
2.08
0.89
1.2
3.1
—
—
—
0
0
232
2543
0.88
0.89
3.2
3.2
6.72
7.18
mmol/l
0.99
190
2083
131
1144
1.17
0.89
4.0
5.4
1.02
1.04
mmol/l
0.33
122
1058
219
1987
1.13
0.87
3.9
4.1
83.31
83.77
%
0.09
208
1941
204
1843
1.14
0.86
6.3
6.7
—
—
—
0
0
11
64
1.73
0.86
2.2
1.3
—
—
—
0
0
27
196
1.39
0.85
4.3
3.9
—
—
—
0
0
6
31
1.94
0.84
3.2
1.8
—
—
—
0
0
70
581
1.22
0.83
5.1
7.3
25.16
24.29
mmol/l
1.35
65
552
121
1056
1.17
0.83
4.0
7.6
1.38
1.20
mmol/l
0.17
96
824
6
113
0.53
0.83
1.7
1.9
90.53
89.47
%
—
6
113
36
277
1.31
0.80
3.3
3.6
3.84
3.99
mmol/l
1.39
36
272
0
25
0.00
0.79
0.0
1.1
—
1.44
—
0
17
5
100
0.50
0.77
2.0
1.3
—
—
—
0
0
53
431
1.24
0.77
3.9
4.1
—
—
—
0
0
15
221
0.67
0.76
1.7
1.6
—
—
—
0
0
155
1389
1.14
0.75
1.9
2.5
11.74
11.99
umol/l
0.19
142
1292
649
6698
0.91
0.74
6.8
6.6
40.90
41.12
mmol/mol
0.23
578
6077
5
25
2.01
0.72
1.4
1.0
—
—
—
0
0
23
168
1.38
0.72
3.3
2.9
—
—
—
0
0
11
68
1.62
0.72
2.2
1.3
—
—
—
0
0
11
68
1.62
0.72
2.3
1.3
—
—
—
0
0
360
3392
1.10
0.71
5.0
6.1
—
—
—
0
0
9
57
1.58
0.71
1.0
1.1
—
285.71
—
0
7
28
212
1.33
0.71
5.0
3.2
7.72
7.85
kpa
0.20
28
207
14
93
1.51
0.69
4.6
3.4
—
—
—
0
0
56
465
1.22
0.69
1.3
1.7
1.63
1.57
g/l
0.17
44
401
9
59
1.53
0.68
1.3
1.2
—
—
—
0
0
231
2494
0.90
0.68
4.4
4.4
—
—
—
0
0
88
1009
0.86
0.67
1.2
1.4
—
—
—
0
0
59
700
0.83
0.67
1.3
1.4
—
—
—
0
0
5
93
0.54
0.67
2.0
3.7
58.40
55.30
%
—
5
79
5
94
0.53
0.67
1.2
1.2
—
—
—
0
0
5
28
1.79
0.66
1.6
1.0
—
—
—
0
0
7
44
1.60
0.65
1.4
4.2
—
23.04
—
0
13
6
102
0.59
0.62
1.8
4.2
—
—
—
0
0
199
1836
1.11
0.61
3.0
2.7
5.11
4.92
e6/l
0.08
172
1657
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
18.13
—
0
15
0
22
0.00
0.59
0.0
1.1
—
1.59
—
0
15
210
1946
1.10
0.59
5.6
4.4
0.00
0.00
estimate
0.50
48
631
44
528
0.83
0.58
1.7
1.4
—
—
—
0
0
0
23
0.00
0.58
0.0
1.7
—
1.48
—
0
23
53
624
0.84
0.57
5.4
4.3
—
—
—
0
0
182
1971
0.91
0.57
2.2
2.5
—
—
—
0
0
13
184
0.70
0.57
1.1
1.0
—
—
—
0
0
163
1772
0.90
0.56
1.2
1.3
—
—
—
0
0
11
159
0.69
0.54
1.1
1.2
38.39
50.85
u/l
0.16
11
136
17
227
0.74
0.54
10.4
11.3
—
—
—
0
0
43
359
1.21
0.53
4.1
4.3
—
—
—
0
0
753
7673
0.92
0.52
31.2
26.0
130.94
132.66
g/l
2.52
736
7515
12
83
1.45
0.52
1.8
1.8
—
—
—
0
0
753
7670
0.92
0.50
31.0
25.8
4.33
4.39
e12/l
3.07
729
7400
753
7669
0.92
0.50
31.0
25.8
6.91
6.91
e9/l
0.03
728
7396
753
7669
0.92
0.50
30.8
25.7
30.53
30.45
pg
0.64
737
7508
753
7669
0.92
0.50
30.9
25.7
91.82
91.76
fl
0.15
737
7509
753
7669
0.92
0.50
31.0
25.8
240.14
237.78
e9/l
0.42
731
7427
343
3593
0.93
0.50
2.4
2.8
—
—
—
0
0
10
144
0.69
0.49
1.3
1.4
—
—
—
0
0
10
68
1.48
0.47
2.4
1.3
—
—
—
0
0
10
68
1.48
0.47
2.3
1.3
—
—
—
0
0
13
176
0.74
0.46
1.1
1.1
—
—
—
0
0
13
94
1.39
0.46
1.1
1.1
—
—
—
0
0
7
49
1.43
0.46
1.3
1.1
—
—
—
0
0
276
2905
0.93
0.46
2.5
3.2
1173.45
1927.60
ng/l
5.53
236
2538
754
7669
0.92
0.45
30.9
26.0
38.48
39.25
%
1.91
662
7061
96
869
1.12
0.44
2.4
2.6
7.03
6.01
ug/l
0.29
69
751
5
32
1.57
0.42
5.0
3.0
—
—
—
0
0
14
184
0.76
0.42
1.4
1.2
—
656.00
—
0
5
0
16
0.00
0.41
0.0
6.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.9
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
4.90
—
0
10
137
1272
1.09
0.39
1.9
2.5
2.21
2.26
g/l
0.49
126
1175
26
313
0.83
0.39
2.7
2.0
—
—
—
0
0
57
642
0.88
0.39
1.6
1.5
—
—
—
0
0
11
148
0.74
0.39
1.0
1.1
—
—
—
0
0
31
261
1.19
0.38
3.5
3.1
0.77
0.86
nmol/l
0.67
24
201
104
955
1.10
0.38
4.0
8.0
94.25
95.43
%
0.74
99
917
19
236
0.80
0.38
6.9
4.4
7.41
7.42
ph
0.22
14
211
13
98
1.33
0.37
1.0
1.1
—
—
—
0
0
5
78
0.64
0.35
3.0
3.7
29.63
40.66
mg/l
—
5
68
73
661
1.11
0.35
3.4
3.6
94.97
95.30
ng/l
0.01
65
572
9
122
0.74
0.35
1.4
1.4
—
—
—
0
0
17
136
1.25
0.33
1.8
1.5
3.10
6.39
iu/l
—
9
39
734
7447
0.94
0.33
11.2
11.4
22.99
25.20
u/l
3.09
695
7124
42
477
0.88
0.33
4.8
4.3
—
—
—
0
0
248
2589
0.94
0.32
2.2
2.6
—
—
—
0
0
6
47
1.28
0.32
1.5
1.6
96.00
90.51
umol/l
—
6
47
52
465
1.12
0.32
2.4
3.1
3.63
5.27
e9/l
1.58
36
344
573
5611
1.05
0.32
29.1
23.4
331.93
331.37
g/l
0.78
558
5562
13
101
1.29
0.32
1.5
1.3
100.83
107.57
u/ml
—
6
14
7
53
1.32
0.31
2.1
2.1
—
—
—
0
0
7
55
1.27
0.30
6.6
3.5
—
—
—
0
0
8
109
0.73
0.29
1.6
1.6
—
—
—
0
0
8
110
0.73
0.29
1.9
1.3
—
—
—
0
0
94
875
1.08
0.28
1.5
1.4
—
—
—
0
0
63
688
0.91
0.28
1.9
2.1
332.10
150.13
ug/g
0.99
49
544
10
77
1.30
0.26
1.1
1.7
—
—
—
0
0
326
3358
0.96
0.26
5.1
5.7
2.87
4.99
ug/l
0.94
284
2969
5
75
0.66
0.26
1.2
1.1
—
—
—
0
0
9
73
1.24
0.25
1.1
1.2
—
—
nmol/l
—
0
0
9
75
1.20
0.25
1.1
1.2
—
—
—
0
0
25
217
1.16
0.24
1.2
1.2
—
—
—
0
0
10
126
0.79
0.24
5.4
2.8
—
—
—
0
0
10
78
1.28
0.24
1.0
1.2
—
251.08
—
0
27
36
322
1.12
0.24
1.1
1.1
236.42
159.13
iu/ml
0.38
16
114
128
1215
1.06
0.23
2.0
2.5
20.69
21.70
%
0.49
100
1042
10
125
0.80
0.23
1.7
1.6
—
—
—
0
0
5
41
1.22
0.22
1.2
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
280.30
—
0
6
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
19.58
—
0
10
0
12
0.00
0.21
0.0
1.0
—
10.80
—
0
5
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
0
12
0.00
0.21
0.0
2.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
13
0.00
0.21
0.0
8.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.6
—
—
—
0
0
34
376
0.90
0.20
1.1
1.3
—
—
—
0
0
13
155
0.84
0.20
1.5
1.6
—
—
—
0
0
9
112
0.80
0.20
1.8
1.4
—
—
—
0
0
6
50
1.20
0.19
1.0
1.2
—
—
—
0
0
57
611
0.93
0.18
1.5
1.4
—
—
—
0
0
19
217
0.87
0.18
1.2
1.6
—
—
—
0
0
84
887
0.94
0.18
2.3
2.8
7.01
10.07
umol/l
1.72
72
788
17
147
1.16
0.18
2.8
2.5
—
—
—
0
0
54
578
0.93
0.17
4.2
8.8
1.65
1.38
%
0.91
54
572
5
67
0.75
0.17
1.2
1.1
—
—
—
0
0
5
69
0.72
0.17
1.2
1.0
—
—
—
0
0
8
71
1.13
0.16
2.1
1.5
11.75
10.68
%
—
8
71
13
111
1.17
0.16
1.1
1.1
—
—
—
0
0
15
130
1.16
0.15
2.3
3.0
—
—
—
0
0
160
1550
1.04
0.15
1.4
1.7
1.59
1.42
mg/l
0.26
130
1223
64
676
0.94
0.15
3.2
3.9
1.24
1.22
mmol/l
1.44
53
588
54
572
0.94
0.14
4.2
9.0
0.70
0.67
%
0.16
54
566
588
5940
0.97
0.14
25.0
20.8
14.94
15.44
%
1.39
574
5818
21
189
1.11
0.14
1.7
2.5
—
—
—
0
0
20
222
0.90
0.13
2.3
2.4
218.59
82.11
ug/min
—
8
128
21
232
0.90
0.13
3.0
3.3
1.39
1.58
mmol/l
1.10
21
227
26
283
0.92
0.13
5.1
5.4
—
—
—
0
0
13
148
0.88
0.12
1.3
1.2
—
—
—
0
0
36
385
0.93
0.12
1.4
1.3
—
—
—
0
0
15
168
0.89
0.11
1.5
1.2
—
2.81
—
0
17
12
136
0.88
0.11
2.1
1.7
—
—
—
0
0
17
187
0.91
0.10
3.5
4.2
15.28
29.72
mg/l
2.80
11
120
13
145
0.90
0.09
1.6
2.0
—
—
—
0
0
5
48
1.04
0.09
1.0
1.2
—
—
—
0
0
12
134
0.89
0.08
1.0
1.5
—
—
—
0
0
6
56
1.07
0.08
1.7
2.8
—
—
—
0
0
520
5241
0.98
0.08
4.5
4.4
—
—
—
0
0
5
60
0.83
0.08
1.4
1.2
—
—
—
0
0
5
62
0.81
0.08
2.2
2.1
0.94
2.11
ug/l
—
5
51
5
63
0.79
0.08
2.2
2.1
2.86
3.22
ug/l
—
5
58
13
117
1.11
0.08
1.5
1.2
—
—
—
0
0
56
581
0.96
0.08
1.4
1.5
—
—
—
0
0
52
540
0.96
0.07
2.1
2.3
13.73
12.17
nmol/l
0.64
47
465
122
1246
0.98
0.07
1.8
2.1
—
—
—
0
0
9
85
1.06
0.07
3.6
3.1
3.46
5.31
nmol/l
—
9
85
9
85
1.06
0.07
1.2
1.2
—
—
—
0
0
22
206
1.07
0.07
3.7
2.5
—
—
—
0
0
15
140
1.07
0.04
2.3
2.8
—
—
—
0
0
186
1880
0.99
0.04
4.2
4.0
—
—
—
0
0
16
150
1.07
0.04
1.6
1.7
47.94
44.01
nmol/l
0.27
16
141
10
91
1.10
0.04
1.4
2.3
—
—
—
0
0
10
109
0.92
0.04
1.5
1.2
—
—
—
0
0
750
7484
1.01
0.03
25.7
21.1
139.65
139.56
mmol/l
0.35
730
7275
34
350
0.97
0.03
1.4
1.3
—
—
—
0
0
83
820
1.01
0.02
1.4
1.3
412.17
444.84
titre
0.13
23
190
58
572
1.01
0.01
2.9
3.2
130.41
125.40
g/l
1.00
58
557
722
7227
1.00
0.00
19.8
17.0
—
—
—
0
0
10
96
1.04
0.00
3.0
2.7
—
—
—
0
0
14
136
1.03
0.00
1.9
3.1
4.23
4.66
e9/l
0.36
14
136
42
424
0.99
0.00
2.2
2.9
—
—
—
0
0
22
222
0.99
0.00
1.1
4.2
—
—
—
0
0
42
418
1.01
0.00
1.3
1.3
—
—
—
0
0
750
7497
1.00
0.00
25.7
21.3
3.96
4.01
mmol/l
7.23
730
7281
49
489
1.00
0.00
4.6
11.0
—
—
—
0
0
10
97
1.03
0.00
1.0
1.1
—
—
—
0
0
14
143
0.98
0.00
1.9
3.3
58.93
60.36
%
0.17
14
143
11
111
0.99
0.00
1.3
1.1
359.20
317.71
u/ml
—
5
55
31
305
1.02
0.00
2.1
2.8
0.18
0.29
g/l
—
9
120
5
56
0.89
0.00
2.2
1.4
—
38.40
—
0
5
0
5
0.00
-0.00
0.0
15.6
—
130.40
—
0
5
5
50
1.00
-0.00
2.0
2.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
1.92
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.4
—
0.33
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
74
0.95
-0.00
1.1
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint G6_DEGENOTH and mortality.

Females

Parameter HR [95% CI] p-value
G6_DEGENOTH 3.447 [3.0, 3.96] < 0.001
Birth year 0.997 [0.99, 1.01] 0.576

During the follow-up period (1.1.1998 — 31.12.2019), 2005 out of 3191 females with G6_DEGENOTH died.

Males

Parameter HR [95% CI] p-value
G6_DEGENOTH 3.577 [3.04, 4.2] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 2129 out of 3230 males with G6_DEGENOTH died.

Mortality risk

Mortality risk for people of age

years, who have G6_DEGENOTH.

N-year risk Females Males
1 0.489% 0.688%
5 2.564% 3.686%
10 5.012% 9.047%
15 9.392% 16.18%
20 16.978% 26.346%

Relationships between endpoints

Index endpoint: G6_DEGENOTH – Other and unspecified degenerative diseases of nervous system

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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