Glycosuria

R18_GLYCOSURIA

renal glycosuria: An autosomal inherited disorder due to defective reabsorption of GLUCOSE by the PROXIMAL RENAL TUBULES. The urinary loss of glucose can reach beyond 50 g/day. It is attributed to the mutations in the SODIUM-GLUCOSE TRANSPORTER 2 encoded by the SLC5A2 gene.

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — R81 Cause of death: ICD-10 — R81 2 out of 7 registries used, show all original rules.	65
4. Check minimum number of events None	65
5. Include endpoints None	65
6. Filter based on genotype QC (FinnGen only)	65

Control definitions (FinnGen only)

Control exclude: R18_ABNORMAL_FINDI_EXAMI_URINE_WO_DIAGNOSIS

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: R8[0-2]
Name in latin: Glucosuria

NAME	R18_GLYCOSURIA
CONTROL_EXCLUDE	R18_ABNORMAL_FINDI_EXAMI_URINE_WO_DIAGNOSIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	R81
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	R81
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Glycosuria based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	65	45	20
Unadjusted period prevalence (%)	0.01	0.02	0.01
Median age at first event (years)	39.63	30.13	61.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
57: Matched controls
571

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

R81

ICD-10 Finland

Glycosuria

+∞

81.7

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

4.23

4.96

2.3

2.4

26.58

23.52

—

(3026008) Bacteria identified in Urine by Culture

141

2.73

3.69

3.8

2.3

—

(3012544) pH of Venous blood

3.65

3.41

4.4

9.5

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

3.55

3.28

4.5

9.3

6.10

5.92

kpa

0.21

(3004119) Hemoglobin [Mass/volume] in Venous blood

5.54

3.16

3.0

13.3

132.13

123.31

g/l

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

220

2.43

3.04

3.5

2.9

69.22

70.65

ug/l

0.04

206

(3024354) Oxygen [Partial pressure] in Venous blood

3.63

2.91

3.9

10.5

4.62

5.29

kpa

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

6.48

2.76

3.0

1.6

25.13

24.17

mmol/l

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

4.01

2.69

1.4

1.7

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

5.09

2.67

2.7

2.1

—

(3037467) Urinalysis macro (dipstick) panel - Urine

346

2.48

2.65

5.4

3.7

—

(3019198) Lymphocytes [#/volume] in Blood

246

2.17

2.38

7.1

6.5

1.84

1.97

e9/l

0.50

222

(3001604) Monocytes [#/volume] in Blood

237

2.16

2.37

7.1

6.6

0.57

0.55

e9/l

0.26

210

(3006315) Basophils [#/volume] in Blood

237

2.16

2.37

7.1

6.7

0.03

0.04

e9/l

0.23

209

(3000330) Specific gravity of Urine by Test strip

4.22

2.32

2.4

2.2

—

(3015736) pH of Urine

177

2.15

2.30

4.7

3.1

—

(3032080) INR in Blood by Coagulation assay

121

2.24

5.9

8.1

2.69

1.10

inr

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

129

2.21

2.24

2.4

2.6

53.48

61.51

u/l

0.54

120

(3018010) Neutrophils/100 leukocytes in Blood

232

2.10

2.23

7.7

6.2

59.97

55.78

1.56

219

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

172

2.10

2.16

4.9

3.2

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

474

2.64

2.13

23.9

12.0

3.89

3.92

mmol/l

0.23

456

(3020682) Albumin/Creatinine [Ratio] in Urine

108

2.23

2.12

4.5

3.5

1.02

15.76

mg/mmol

0.95

(3022096) Basophils/100 leukocytes in Blood

218

2.04

2.08

8.0

6.5

0.48

0.62

0.95

203

(3002030) Lymphocytes/100 leukocytes in Blood

237

2.03

2.05

8.0

6.3

26.19

30.17

1.90

225

(3019069) Monocytes/100 leukocytes in Blood

228

2.03

2.05

8.1

6.6

8.34

8.24

0.07

215

(3019550) Sodium [Moles/volume] in Serum or Plasma

475

2.62

1.98

23.8

11.9

139.53

139.63

mmol/l

0.15

459

(3022145) Colonoscopy Study observation

2.82

1.88

1.2

1.3

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

4.41

1.86

4.0

2.2

55.50

50.40

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

146

2.02

1.86

1.5

1.8

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

509

2.72

1.81

17.8

11.9

68.68

69.54

umol/l

0.11

509

(3021960) Folate [Moles/volume] in Serum or Plasma

2.12

1.72

1.7

1.5

17.69

20.60

nmol/l

0.40

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

3.37

1.70

1.2

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.44

1.68

1.9

1.6

—

(42870588) Differential panel, method unspecified - Blood

135

1.95

1.64

7.1

8.3

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.25

1.62

1.4

2.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.39

1.61

2.6

1.7

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

154

1.89

1.56

3.5

3.2

33.67

30.47

u/l

0.28

149

(3003396) Base excess in Arterial blood by calculation

2.44

1.55

9.0

6.4

4.80

1.66

mmol/l

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

3.04

1.54

12.0

6.9

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.04

1.54

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

227

1.81

1.50

5.2

3.3

0.00

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

227

1.81

1.50

7.2

4.5

0.00

estimate

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.68

1.50

5.1

11.4

25.00

24.65

mmol/l

—

(3003327) Ova and parasites identified in Stool by Light microscopy

3.29

1.46

1.6

1.8

—

(3023511) Choriogonadotropin [Units/volume] in Urine

2.65

1.33

1.2

—

(3009261) Glucose [Presence] in Urine by Test strip

234

1.72

1.31

5.6

3.3

0.00

estimate

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

513

2.21

1.29

11.8

8.5

25.40

24.98

u/l

0.06

494

(3041096) Erythrocytes [Presence] in Urine by Automated

137

1.79

1.26

3.1

2.6

—

(3005322) IgE [Units/volume] in Serum or Plasma

2.20

1.20

1.3

1.2

105.20

245.78

u/ml

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

148

1.74

1.19

2.6

1.8

92.05

90.84

pmol/l

0.05

(3012516) Albumin [Mass/volume] in Urine

106

1.82

1.18

3.2

3.0

15.14

122.26

mg/l

0.87

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

2.25

1.09

1.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.11

1.09

3.1

1.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.89

1.08

2.5

1.8

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

109

1.76

1.07

5.0

3.5

12.10

22.46

ng/l

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

500

1.87

0.93

19.8

11.2

21.28

21.29

mg/l

0.00

378

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.17

0.92

1.2

1.1

—

(1761868) Lipid panel - Serum or Plasma

161

1.55

0.83

3.0

2.5

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.90

0.81

3.0

2.7

—

(3023368) Bacteria identified in Blood by Culture

102

1.61

0.76

4.4

4.2

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.08

0.74

1.0

2.2

204.20

219.34

ng/l

—

(3009542) Hematocrit [Volume Fraction] of Blood

475

1.63

0.74

22.9

12.7

39.28

40.25

0.40

386

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

221

1.47

0.73

4.4

4.0

—

(3000991) Gas panel - Venous blood

1.79

0.72

14.1

7.3

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

1.75

0.71

3.0

3.9

34.14

35.48

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

423

1.52

0.70

4.5

3.6

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.92

0.70

1.2

—

(3000494) Fungus identified in Specimen by Culture

1.70

0.69

2.3

1.4

—

(3044889) 12 lead EKG panel

273

1.42

0.66

3.7

3.1

—

(3021589) Normoblasts [#/volume] in Blood

217

1.42

0.63

11.9

8.9

0.00

e9/l

0.71

171

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

161

1.45

0.62

5.5

2.7

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

125

1.49

0.62

2.1

2.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.61

0.0

1.4

—

(3013512) EKG study

1.50

0.51

4.1

3.3

—

(36660697) Celiac disease serology panel - Serum

1.58

0.50

1.9

1.2

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.48

0.48

3.7

4.7

1.67

1.69

—

(40768797) Stomach Pathology biopsy report

1.52

0.45

1.1

1.2

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.61

0.43

15.4

12.3

25.16

25.56

mmol/l

—

(40761511) CBC panel - Blood by Automated count

528

1.44

0.40

17.1

9.6

—

(3007461) Platelets [#/volume] in Blood

565

1.48

0.36

28.3

16.7

280.32

257.98

e9/l

1.64

554

(40768804) Tissue Pathology biopsy report

187

1.27

0.32

3.1

1.9

—

(3029937) Albumin [Presence] in Urine by Test strip

121

1.31

0.32

7.5

3.5

0.00

estimate

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.36

0.32

1.1

1.8

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.35

0.30

5.7

3.5

0.85

0.83

mmol/l

—

(3042936) Bacteria identified in Isolate by Culture

1.31

0.29

3.6

1.8

—

(40760892) CBC W Ordered Manual Differential panel - Blood

115

1.28

0.26

6.1

4.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.33

0.26

1.2

1.4

—

(3010813) Leukocytes [#/volume] in Blood

567

1.44

0.26

28.3

16.7

7.19

6.64

e9/l

1.36

554

(3024731) MCV [Entitic volume]

566

1.46

0.26

28.3

16.6

89.62

89.74

0.07

558

(3000963) Hemoglobin [Mass/volume] in Blood

566

1.46

0.26

29.3

16.7

132.32

134.69

g/l

0.69

558

(3035941) MCH [Entitic mass]

566

1.46

0.26

28.3

16.5

29.82

29.91

0.14

557

(3026361) Erythrocytes [#/volume] in Blood

566

1.46

0.26

28.3

16.6

4.44

4.53

e12/l

0.75

554

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

135

1.25

0.24

1.5

1.6

—

(4010399)

1.34

0.24

1.2

—

(3022621) pH of Urine by Test strip

1.27

0.23

4.2

2.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.24

0.22

1.0

1.2

—

(4034850)

0.00

0.21

0.0

25.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.21

0.0

1.1

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

0.21

0.0

1.5

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.21

0.0

1.3

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.2

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

2.2

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.20

0.0

1.1

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.19

0.18

2.9

1.5

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

120

1.21

0.18

2.2

2.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.74

0.18

1.4

1.5

—

(3003694) ABO and Rh group [Type] in Blood

161

0.83

0.17

1.5

1.6

—

(36304419) Bacteria [Presence] in Urine

132

1.18

0.15

4.5

2.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

441

1.15

0.14

16.2

9.5

92.27

90.80

ml/min/173m2

0.17

340

(46235355) HIV 1 and 2 tests - Meaningful Use set

162

1.15

0.13

1.6

1.9

—

(3007164) IgA [Mass/volume] in Serum or Plasma

124

1.16

0.12

2.0

1.5

1.67

2.49

g/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

106

1.16

0.10

2.2

2.0

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

1.12

0.08

3.6

4.3

—

24.54

—

(21494755) Public health laboratory ask at order entry panel

1.10

0.08

1.1

1.2

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.09

0.08

11.3

2.3

2.70

2.45

mmol/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.06

0.08

2.9

1.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.05

0.07

1.3

1.7

—

(3044640) Blood type and Crossmatch panel - Blood

139

1.10

0.06

2.2

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

100

1.12

0.05

8.3

3.6

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

120

1.10

0.05

1.8

1.4

—

(40758558) Short blood count panel - Blood

142

1.07

0.03

8.9

6.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

116

1.04

0.00

1.8

1.6

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.7

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.7

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

11.5

—

0.69

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

2.5

—

(3022411) Androstenedione [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

7.77

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.0

1.5

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.1

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

0.0

1.3

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

0.50

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.3

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.3

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.9

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.0

3.8

—

3.46

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.3

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

4.0

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

0.0

1.2

—

(4198724)

0.00

0.0

1.1

—

(4306422)

0.00

0.0

1.4

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

2.4

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.3

—

91.23

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

1.8

—

0.73

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.8

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

11.90

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.0

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.1

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.4

—

13.08

—

(3002256) Pathology report gross observation

0.90

0.00

1.0

1.2

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.0

3.8

—

55.13

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.0

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: R18_GLYCOSURIA – Glycosuria

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Glycosuria

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Glycosuria (R18_GLYCOSURIA)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints