Other bursitis of elbow

M13_BURSELBOWOTH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M70.3
  • Hospital discharge: ICD-9 7263X
  • Cause of death: ICD-10 M70.3
  • Cause of death: ICD-9 7263X

2 out of 7 registries used, show all original rules.

280

4. Check minimum number of events

None

280

5. Include endpoints

None

280

6. Filter based on genotype QC (FinnGen only)

280

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M70
Name in latin
Bursitis cubiti

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2048 444 1588
Only index persons 1871 413 1458
Unadjusted period prevalence (%)
Whole population 0.04 0.01 0.04
Only index persons 0.05 0.02 0.06
Median age at first event (years)
Whole population 56.06 59.81 54.95
Only index persons 55.44 58.91 54.45

-FinnGen-

Key figures

All Female Male
Number of individuals 280 78 202
Unadjusted period prevalence (%) 0.07 0.03 0.09
Median age at first event (years) 60.19 59.33 60.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
239
Matched controls
2391
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M70.3
ICD-10 Finland
Other bursitis of elbow
16384.0
323.0
233
*
M70.2
ICD-10 Finland
Olecranon bursitis
52.9
53.3
63
16
NCM20
NOMESCO Finland
Excision of synovial ganglion of elbow or forearm
444.7
39.2
38
*
L10
ICPC
Elbow symptom/complaint
16.8
25.5
41
29
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.3
17.6
134
659
J01FF01
ATC
clindamycin; systemic
3.5
16.0
95
381
N02AJ06
ATC
codeine and paracetamol; systemic
3.3
15.6
107
473
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.4
15.4
61
172
A46
ICD-10 Finland
Erysipelas
4.3
15.2
63
185
J01DB01
ATC
cefalexin; oral
4.1
14.5
211
1551
M79.6
ICD-10 Finland
Pain in limb
3.2
12.6
78
313
N02AX02
ATC
tramadol; systemic, rectal
2.8
12.1
112
578
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
24.3
11.7
16
7
M71.1
ICD-10 Finland
Other infective bursitis
+∞
11.5
11
*
N03AX16
ATC
pregabalin; oral
3.3
11.2
62
228
M25.5
ICD-10 Finland
Pain in joint
3.0
10.7
71
292
TPH04
NOMESCO Finland
Cathetrisation of vein
3.1
10.6
68
275
H02AB06
ATC
prednisolone; systemic
2.5
10.5
124
719
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
19.9
10.4
15
8
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.2
9.8
57
213
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
9.8
84
405
M71.0
ICD-10 Finland
Abscess of bursa
57.4
9.7
11
*
M10.9
ICD-10 Finland
Gout, unspecified
4.8
9.7
32
74
L04AA13
ATC
leflunomide; oral
15.9
9.6
15
10
N03AX12
ATC
gabapentin; oral
3.6
9.5
44
140
SPAT1255
SPAT
Intravenous administration of medicine
4.9
9.5
31
71
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
5.8
9.4
26
49
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
8.9
9.3
19
23
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
9.6
9.2
18
20
A02BC02
ATC
pantoprazole; systemic
2.4
9.2
159
1087
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
5.7
8.9
25
48
S18
ICPC
Laceration/cut
2.3
8.8
116
691
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.1
8.4
48
179
M71.9
ICD-10 Finland
Bursopathy, unspecified
34.6
8.1
10
*
M01AH01
ATC
celecoxib; oral (coxibs)
3.1
8.0
46
172
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.9
8.0
32
90
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.8
7.9
33
96
J01DA01
ATC
[U] cefalexin; systemic
2.2
7.6
150
1045
WX320
NOMESCO Finland
Spinalanesthesy
2.6
7.6
60
270
R03BB04
ATC
tiotropium bromide; inhalant
3.4
7.5
36
118
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
8.8
7.4
15
18
SPAT1263
SPAT
Sampling
2.2
7.4
102
604
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.8
7.2
23
52
Z3226
NOMESCO Finland
Physiotherapist
2.7
7.2
51
217
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.3
7.1
35
117
M67.4
ICD-10 Finland
Ganglion
7.9
7.0
15
20
M48.0
ICD-10 Finland
Spinal stenosis
3.2
6.9
36
125
N02AA05
ATC
oxycodone; systemic
3.0
6.9
42
159
M04AA01
ATC
allopurinol; systemic
2.8
6.8
45
181
M01AH05
ATC
etoricoxib; oral
2.0
6.7
129
870
L17
ICPC
Foot/toe symptom/complaint
2.4
6.7
60
288
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
3.7
6.7
28
82
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
5.3
6.7
19
38
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
9.1
6.6
13
15
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.1
6.4
24
64
M03BX02
ATC
tizanidine; oral
2.0
6.4
135
940
X58
ICD-10 Finland
Exposure to other specified factors
2.9
6.4
38
145
Z3231
NOMESCO Finland
Registered nurse
2.2
6.4
72
387
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.7
6.4
46
196
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
9.6
6.4
12
13
ZXD20
NOMESCO Finland
Day surgery
3.0
6.4
37
139
E0000UV
ATC
NA
2.1
6.3
88
519
M03BC01
ATC
orphenadrine (citrate); systemic
2.5
6.3
53
246
B37.03
ICD-10 Finland
Chronic atrophic candida infection in the mouth
+∞
6.3
6
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
+∞
6.3
6
*
M13.9
ICD-10 Finland
Arthritis, unspecified
4.1
6.2
23
61
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.5
6.2
28
88
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.8
6.2
40
161
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
9.0
6.1
12
14
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
9.0
6.1
12
14
X59
ICD-10 Finland
Exposure to unspecified factor
2.7
6.1
44
187
Z71.8
ICD-10 Finland
Other specified counselling
2.3
6.0
58
287

Mortality – FinRegistry

Association

Association between endpoint M13_BURSELBOWOTH and mortality.

Females

Parameter HR [95% CI] p-value
M13_BURSELBOWOTH 1.937 [1.38, 2.72] < 0.001
Birth year 0.994 [0.99, 1.0] 0.187

During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 341 females with M13_BURSELBOWOTH died.

Males

Parameter HR [95% CI] p-value
M13_BURSELBOWOTH 1.873 [1.51, 2.32] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 294 out of 1209 males with M13_BURSELBOWOTH died.

Mortality risk

Mortality risk for people of age

years, who have M13_BURSELBOWOTH.

N-year risk Females Males
1 0.152% 0.299%
5 1.068% 2.092%
10 2.569% 4.976%
15 5.234% 9.559%
20 9.504% 16.253%

Relationships between endpoints

Index endpoint: M13_BURSELBOWOTH – Other bursitis of elbow

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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