No definition available.
Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
AB1_HIV_INFECT_PARASITES
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
93 |
4. Check minimum number of eventsNone |
93 |
5. Include endpointsNone |
93 |
6. Filter based on genotype QC (FinnGen only) |
80 |
Control definitions (FinnGen only)
- Control exclude
- AB1_HIV
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
based on the number of shared cases.
Similar with more cases:
- Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
- Human immunodeficiency virus [HIV] disease
- Certain infectious and parasitic diseases
- Certain infectious and parasitic diseases
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 721 | 224 | 457 |
| Only index persons | 565 | 193 | 372 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 43.20 | 40.28 | 45.11 |
| Only index persons | 43.37 | 39.02 | 45.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 80 | 19 | 61 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.03 |
| Median age at first event (years) | 47.04 | 51.28 | 45.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 93
- Matched controls
- 930
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
+∞
81.7
66
*
WW200
NOMESCO Finland
Immunization
219.6
67.8
64
9
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
+∞
67.0
56
*
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
31.6
62.0
50
33
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
+∞
54.7
47
*
B20.6
ICD-10 Finland
HIV disease resulting in Pneumocystis jirovecii pneumonia
+∞
35.7
32
*
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
12.9
24.8
28
30
B20.9
ICD-10 Finland
HIV disease resulting in unspecified infectious or parasitic disease
+∞
21.7
20
*
Z3231
NOMESCO Finland
Registered nurse
7.3
20.9
57
166
Z21
ICD-10 Finland
Asymptomatic human immunodeficiency virus [HIV] infection status
+∞
18.3
17
*
Z25.1
ICD-10 Finland
Need for immunization against influenza
20.7
17.5
26
17
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.2
15.7
67
273
B20.0
ICD-10 Finland
HIV disease resulting in mycobacterial infection
+∞
13.9
13
*
Z2221
NOMESCO Finland
Medical doctor
5.1
13.8
49
167
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
7.5
13.3
22
37
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.1
13.2
41
125
B20.3
ICD-10 Finland
HIV disease resulting in other viral infections
+∞
11.7
11
*
B20.1
ICD-10 Finland
HIV disease resulting in other bacterial infections
+∞
11.7
11
*
Z73.3
ICD-10 Finland
Stress, not elsewhere classified
32.5
11.1
14
5
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
29.8
10.1
13
5
B23.0
ICD-10 Finland
Acute HIV infection syndrome
+∞
9.5
9
*
J05AB11
ATC
valaciclovir; oral
4.9
8.8
23
59
QAJ99
NOMESCO Finland
Other aesthetic operations on skin of head or neck
+∞
8.5
8
*
B20.7
ICD-10 Finland
HIV disease resulting in multiple infections
+∞
8.5
8
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.7
8.1
22
58
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.6
7.9
22
59
R4110
NOMESCO Finland
Physiotherapy
3.4
7.5
40
169
JN4BD
NOMESCO Finland
Extensive body CT
5.0
7.4
18
43
B20.4
ICD-10 Finland
HIV disease resulting in candidiasis
+∞
7.4
7
*
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
4.2
6.8
21
61
XF400
NOMESCO Finland
ECG with 12 standard connections
3.7
6.7
26
89
WYA30, ,
SPAT
74.8
6.5
7
*
N06AB04
ATC
citalopram; systemic
3.5
6.4
28
103
B20.2
ICD-10 Finland
HIV disease resulting in cytomegaloviral disease
+∞
6.3
6
*
Z2446
NOMESCO Finland
Social worker
5.7
6.1
17
35
B18.2
ICD-10 Finland
Chronic viral hepatitis C
16.4
6.0
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
79
97
48.46
71.79
14.4
6.5
0.94
0.98
mmol/l
0.82
79
92
53
60
19.21
47.88
2.5
2.5
30.83
27.32
u/l
0.46
53
50
65
192
8.92
24.22
2.2
1.8
1.34
1.50
mmol/l
0.77
65
167
76
273
10.76
23.00
15.7
3.7
31.78
33.05
u/l
0.25
76
261
27
32
11.48
22.21
3.1
2.6
—
—
—
0
0
26
30
11.64
21.77
3.0
2.3
—
—
—
0
0
73
288
8.14
18.77
5.6
5.6
38.07
36.20
g/l
2.00
73
274
77
345
8.16
16.44
4.3
3.1
0.00
0.02
estimate
0.49
11
64
77
351
7.94
15.94
7.7
4.2
0.00
0.00
estimate
—
10
61
77
357
7.72
15.45
4.3
3.1
0.00
0.00
estimate
—
8
57
35
84
6.08
15.02
3.1
2.2
—
—
—
0
0
33
77
6.09
14.55
2.8
2.0
—
—
—
0
0
78
434
5.94
10.78
6.4
4.8
6.23
6.79
mmol/l
2.01
78
409
48
193
4.07
10.26
5.3
3.0
0.13
0.37
e6/l
1.15
34
148
13
5
29.84
10.12
1.1
1.0
—
—
—
0
0
8
0
+∞
8.45
5.1
0.0
—
—
—
0
0
31
104
3.97
8.33
4.8
2.7
0.20
0.97
e6/l
1.48
15
53
51
239
3.51
8.24
5.1
3.1
—
—
—
0
0
11
7
17.57
7.43
5.0
3.4
—
—
—
0
0
31
114
3.58
7.18
4.8
2.6
0.27
0.89
e6/l
1.37
15
63
10
7
15.79
6.56
4.3
3.1
—
—
—
0
0
11
10
12.27
6.49
2.6
1.3
—
—
—
0
0
12
15
9.00
6.05
1.2
1.4
—
—
—
0
0
14
23
6.96
5.96
4.1
2.6
—
—
—
0
0
15
28
6.17
5.84
1.2
1.4
131.20
319.36
miu/ml
—
5
16
19
57
3.93
5.81
3.3
2.6
71.78
63.33
ml/min/173m2
—
9
24
15
29
5.96
5.69
1.3
1.5
—
—
—
0
0
14
25
6.39
5.64
1.3
1.2
—
—
—
0
0
13
22
6.68
5.45
2.3
1.3
—
—
—
0
0
55
334
2.58
4.74
5.1
7.4
1.20
1.20
mmol/l
0.13
43
296
12
24
5.57
4.50
1.3
1.3
1.68
0.14
iu/ml
—
6
5
7
6
12.47
4.35
1.3
2.0
—
—
—
0
0
10
18
6.08
4.10
4.0
1.4
—
—
—
0
0
25
112
2.69
3.92
1.7
1.9
—
—
—
0
0
20
84
2.76
3.52
1.8
1.8
—
—
—
0
0
14
48
3.26
3.47
1.4
1.6
—
—
—
0
0
20
86
2.69
3.36
1.8
1.9
—
—
—
0
0
17
67
2.88
3.35
2.3
2.8
—
—
—
0
0
7
12
6.21
3.08
5.3
4.8
47.57
54.25
%
—
7
12
5
5
10.46
3.01
1.4
1.6
1557.40
504.80
u/ml
—
5
5
82
679
2.76
2.67
34.3
16.6
13.50
14.85
%
6.05
82
671
6
11
5.74
2.58
1.0
1.2
—
—
—
0
0
7
16
4.64
2.52
1.1
1.8
—
—
—
0
0
7
16
4.64
2.52
1.1
1.8
—
—
—
0
0
39
255
1.91
2.33
1.8
1.8
92.45
87.92
pmol/l
0.34
22
127
87
774
2.92
2.16
22.2
12.9
19.89
23.21
mg/l
0.62
78
601
7
20
3.70
2.10
1.0
1.1
—
—
—
0
0
6
17
3.70
1.87
1.2
1.2
—
—
—
0
0
26
160
1.87
1.81
2.2
2.3
—
—
—
0
0
84
745
2.32
1.76
25.7
11.6
84.00
86.81
ml/min/173m2
0.68
77
615
6
19
3.30
1.69
1.8
2.5
4.05
3.48
g/l
—
6
19
10
42
2.54
1.68
7.4
8.7
24.70
25.01
mmol/l
—
10
42
33
228
1.69
1.54
2.3
2.2
118.48
222.73
u/l
1.93
33
221
17
275
0.53
1.53
2.6
3.6
17.00
55.51
ng/l
—
8
178
22
141
1.73
1.33
4.0
3.2
11.57
267.07
ng/l
2.05
14
114
5
18
2.87
1.30
1.4
1.4
—
—
—
0
0
5
18
2.87
1.30
1.0
2.5
271.20
166.78
%
—
5
18
43
330
1.56
1.28
17.1
12.3
1.22
1.28
inr
—
10
93
5
20
2.58
1.16
1.2
1.8
—
—
—
0
0
12
67
1.91
1.10
2.0
1.4
—
—
—
0
0
5
22
2.34
1.04
1.0
1.8
97.00
86.45
%
—
5
22
42
333
1.48
1.02
2.7
2.6
—
—
—
0
0
6
28
2.22
0.93
1.3
1.6
2.06
1.44
mg/l
—
6
22
25
323
0.69
0.80
3.7
3.8
22.53
21.63
%
—
6
123
0
26
0.00
0.80
0.0
1.4
—
—
—
0
0
17
118
1.54
0.76
1.9
2.2
13.32
14.34
umol/l
0.20
17
110
5
24
2.14
0.76
1.2
2.5
—
—
—
0
0
11
68
1.70
0.75
1.5
2.5
325.55
387.17
nmol/l
0.55
11
59
5
26
1.97
0.72
1.0
1.2
—
—
—
0
0
21
273
0.70
0.68
5.7
3.1
—
—
—
0
0
25
199
1.35
0.56
4.5
4.1
9.90
9.30
mg/mmol
0.04
20
143
9
62
1.50
0.55
1.0
1.9
52.11
40.27
nmol/l
—
9
62
56
617
0.77
0.55
5.0
3.2
68.45
53.35
u/l
0.36
51
594
14
104
1.41
0.46
1.7
1.6
926.79
1169.23
nmol/l
0.47
14
80
5
33
1.54
0.42
1.0
3.0
—
—
—
0
0
5
35
1.45
0.40
1.0
1.4
—
—
—
0
0
20
238
0.80
0.34
2.8
2.6
0.52
0.70
ug/l
0.77
12
121
12
93
1.33
0.32
9.0
8.1
105.92
104.18
mmol/l
1.28
12
93
58
546
1.17
0.25
3.6
3.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
1.13
—
0
6
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
4.9
—
2373.22
—
0
10
0
13
0.00
0.21
0.0
1.7
—
—
—
0
0
17
151
1.15
0.14
1.2
1.3
—
1.15
—
0
45
5
45
1.12
0.10
13.2
11.4
1.06
1.84
%
—
5
45
13
134
0.97
0.00
1.5
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
199.34
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
0.00
0.0
3.2
—
97.80
—
0
5
0
5
0.00
0.00
0.0
3.2
—
232.20
—
0
5
0
5
0.00
0.00
0.0
1.4
—
121.00
—
0
5
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
3.21
—
0
7
0
8
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
14.45
—
0
8
0
6
0.00
-0.00
0.0
5.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
13.50
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
109.86
—
0
7
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.5
—
—
—
0
0
6
67
0.89
-0.00
2.7
4.0
1.65
74.07
ug/l
—
6
53
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint AB1_HIV_INFECT_PARASITES and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| AB1_HIV_INFECT_PARASITES | 4.062 [2.74, 6.01] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.052 |
During the follow-up period (1.1.1998 — 31.12.2019), 101 out of 367 males with AB1_HIV_INFECT_PARASITES died.
Mortality risk
Mortality risk for people of age
years, who have AB1_HIV_INFECT_PARASITES.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.694% |
| 5 | No data | 4.927% |
| 10 | No data | 12.343% |
| 15 | No data | 22.69% |
| 20 | No data | 36.882% |
Relationships between endpoints
↥Index endpoint: AB1_HIV_INFECT_PARASITES – Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data