This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
141 |
4. Check minimum number of events
Min. number of events
3
|
141 |
5. Include endpointsNone |
141 |
6. Filter based on genotype QC (FinnGen only) |
140 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- First used in FinnGen datafreeze
- DF2
Use of riluzole
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 140 | 63 | 77 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.04 |
| Median age at first event (years) | 65.39 | 65.69 | 65.15 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 141
- Matched controls
- 1410
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N07XX02
ATC
riluzole; oral
+∞
203.7
141
*
G12.2
ICD-10 Finland
Motor neuron disease
10809.8
182.1
135
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
99.8
115.1
62
11
J96.1
ICD-10 Finland
Chronic respiratory failure
58.3
79.7
47
12
N99
ICPC
Neurological disease other
197.2
51.8
51
*
Z51.5
ICD-10 Finland
Palliative care
14.0
47.6
54
60
JDB10
NOMESCO Finland
Percutaneous gastrostomy
116.0
45.2
47
6
R13
ICD-10 Finland
Dysphagia
11.2
34.9
44
55
R47.1
ICD-10 Finland
Dysarthria and anarthria
65.8
31.1
35
7
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
9.9
30.2
41
56
R4130
NOMESCO Finland
Speech therapy
26.9
25.5
35
17
N28
ICPC
Limited function/disability (N)
68.1
20.6
23
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
5.9
19.7
44
100
WX725
NOMESCO Finland
Noninvasive ventilation
8.3
18.5
27
39
R4190
NOMESCO Finland
Nutritional therapy
22.4
18.1
26
14
TJD20
NOMESCO Finland
Change of gastrostomy tube
96.0
15.9
17
*
A28
ICPC
Limited function/disability NOS
4.4
15.7
54
173
R4120
NOMESCO Finland
Occupational therapy
7.0
15.4
26
44
G12.9
ICD-10 Finland
Spinal muscular atrophy, unspecified
+∞
14.8
14
*
R1250
NOMESCO Finland
Evaluation of functional capability
15.7
11.3
18
13
R5599
NOMESCO Finland
Other rehabilitation service
14.5
11.0
18
14
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
9.7
10.5
21
25
XG466
NOMESCO Finland
Sleep oxymetry
9.5
10.0
20
24
SPAT1229
SPAT
Assessment of need for aid
4.8
9.6
24
58
L28
ICPC
Limited function/disability (L)
3.5
9.6
42
153
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
9.4
9.4
19
23
R1260
NOMESCO Finland
Evaluation of communicative skills
17.1
9.2
14
9
TAB00
NOMESCO Finland
Lumbar puncture
7.5
9.1
21
32
N02AA01
ATC
morphine; systemic, rectal
15.7
8.4
13
9
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.9
7.4
24
71
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
21.4
7.2
10
5
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
7.9
6.9
15
21
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
8.5
6.8
14
18
G72.9
ICD-10 Finland
Myopathy, unspecified
15.2
6.5
10
7
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
11.8
6.4
11
10
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
0.2
6.1
6
270
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
68
1105
0.26
14.37
2.9
4.7
1.47
1.44
mmol/l
0.20
55
1006
69
1110
0.26
14.19
2.9
4.7
4.80
4.60
mmol/l
0.62
56
1021
73
1135
0.26
13.97
3.1
5.3
2.77
2.72
mmol/l
0.16
58
1033
68
1076
0.29
11.99
2.6
4.2
1.14
1.30
mmol/l
1.67
55
977
15
5
33.26
11.91
1.0
1.0
—
—
—
0
0
16
10
17.84
10.63
1.0
1.0
—
—
—
0
0
70
1070
0.31
10.48
4.1
6.1
36.54
40.55
mmol/mol
8.55
64
995
16
12
14.85
9.95
1.0
1.1
—
—
—
0
0
16
13
13.70
9.63
1.0
1.1
—
—
—
0
0
18
24
8.43
8.47
1.0
1.3
144.46
294.50
e6/l
0.20
13
16
18
24
8.43
8.47
1.0
1.2
1.25
3.20
e6/l
0.97
12
15
80
1098
0.37
7.41
3.3
4.9
5.80
6.02
mmol/l
1.59
69
997
18
47
4.24
6.49
1.1
2.5
9.28
10.84
g/l
1.22
18
42
18
50
3.98
5.98
1.0
2.4
—
—
—
0
0
9
310
0.24
5.74
1.3
1.7
1.24
1.33
mmol/l
—
9
257
32
141
2.64
5.02
3.9
5.9
5.81
5.05
kpa
1.75
32
133
85
1086
0.45
4.77
12.6
14.4
95.84
78.13
ml/min/173m2
8.58
74
897
31
141
2.54
4.54
4.0
5.8
11.44
12.22
kpa
0.42
31
133
32
570
0.43
4.25
3.5
5.5
0.00
0.00
estimate
-0.00
11
112
101
1196
0.45
4.05
13.7
18.3
56.42
80.14
umol/l
19.96
101
1196
79
1011
0.50
3.82
3.4
4.6
1.83
1.95
mu/l
0.45
74
903
13
34
4.10
3.81
1.1
2.9
0.00
0.00
g/l
-0.00
13
34
34
571
0.47
3.69
2.7
3.9
0.00
0.01
estimate
0.50
11
117
35
574
0.48
3.49
2.7
4.0
0.00
0.00
estimate
-0.00
11
104
24
448
0.44
3.39
3.0
4.2
—
—
—
0
0
43
640
0.53
3.03
3.1
2.7
—
—
—
0
0
30
496
0.50
2.91
3.4
5.1
16.68
2.39
ug/l
0.45
24
443
24
405
0.51
2.38
4.0
4.6
16.99
21.33
%
—
8
206
5
149
0.31
2.32
1.2
1.4
—
—
—
0
0
8
28
2.97
1.89
1.1
1.3
—
—
—
0
0
19
318
0.53
1.77
3.2
3.9
0.00
0.00
estimate
-0.00
11
108
11
49
2.35
1.68
1.2
2.1
37.64
43.32
u/l
0.54
11
42
99
1114
0.63
1.67
12.2
15.9
32.14
23.27
mg/l
1.21
84
910
0
37
0.00
1.36
0.0
1.7
—
255.09
—
0
32
83
953
0.69
1.35
15.6
18.5
14.83
15.00
%
0.10
83
942
15
85
1.86
1.29
5.4
7.6
27.19
24.80
mmol/l
1.64
15
79
22
141
1.66
1.27
3.9
6.2
102.77
103.85
mmol/l
0.44
22
141
0
34
0.00
1.17
0.0
1.2
—
—
—
0
0
0
34
0.00
1.17
0.0
1.2
—
—
—
0
0
72
833
0.72
1.10
2.8
4.4
10.75
12.28
mm/h
0.47
67
756
41
518
0.71
1.06
1.9
2.6
—
—
—
0
0
34
440
0.70
1.00
3.0
3.2
—
—
—
0
0
0
30
0.00
0.98
0.0
1.2
—
—
—
0
0
10
168
0.56
0.94
1.3
2.3
21.10
23.55
%
—
10
142
29
382
0.70
0.94
1.6
2.7
55.12
54.75
u/l
0.02
24
359
19
272
0.65
0.94
1.1
2.0
2.27
3.26
mg/l
0.97
14
235
20
136
1.55
0.93
1.7
1.9
—
—
—
0
0
20
140
1.50
0.82
1.7
2.0
—
—
—
0
0
10
58
1.78
0.82
1.7
3.0
0.67
0.68
%
—
10
58
6
33
1.85
0.80
1.0
1.3
—
1.71
—
0
8
5
26
1.96
0.71
1.2
1.1
—
—
—
0
0
26
198
1.38
0.71
1.5
2.0
—
—
—
0
0
5
27
1.88
0.69
1.0
1.5
—
—
—
0
0
5
27
1.88
0.69
1.0
1.5
—
—
—
0
0
10
62
1.66
0.67
1.7
2.9
0.76
1.22
%
—
10
62
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
0
20
0.00
0.61
0.0
1.1
—
—
—
0
0
0
22
0.00
0.60
0.0
1.8
—
—
—
0
0
0
23
0.00
0.59
0.0
1.1
—
—
—
0
0
26
205
1.33
0.58
1.5
3.1
0.85
0.82
mmol/l
0.35
20
188
6
39
1.56
0.53
1.0
1.6
—
—
—
0
0
29
345
0.80
0.45
3.0
3.1
0.93
0.57
e6/l
0.29
20
257
52
581
0.83
0.44
8.6
14.5
1.24
1.26
inr
0.07
14
173
0
15
0.00
0.41
0.0
1.1
—
94.33
—
0
15
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
17
0.00
0.41
0.0
2.0
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
0
17
0.00
0.41
0.0
1.9
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
—
—
0
0
8
61
1.33
0.40
2.3
1.8
—
—
—
0
0
0
18
0.00
0.40
0.0
1.6
—
—
—
0
0
0
18
0.00
0.40
0.0
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
377.30
—
0
10
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
5
79
0.62
0.36
1.4
3.8
66.40
73.79
ng/l
—
5
70
8
110
0.71
0.30
1.4
1.3
—
—
—
0
0
28
248
1.16
0.24
1.8
1.8
1.49
1.50
mg/l
0.00
20
196
18
208
0.85
0.22
2.3
2.7
0.83
1.15
e6/l
—
10
121
0
11
0.00
0.21
0.0
5.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
203.07
—
0
10
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
183.07
—
0
12
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
13
0.00
0.21
0.0
4.4
—
90.38
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
15
128
1.19
0.19
5.5
3.7
—
—
—
0
0
23
257
0.87
0.18
1.9
2.4
—
—
—
0
0
5
43
1.17
0.10
1.2
1.9
—
—
—
0
0
5
46
1.09
0.09
1.2
2.3
—
—
—
0
0
8
73
1.10
0.07
1.1
1.4
—
—
—
0
0
18
194
0.92
0.07
2.3
2.9
1.22
2.93
e6/l
—
9
108
7
81
0.86
0.07
1.3
1.5
—
—
—
0
0
9
84
1.08
0.07
2.1
2.4
263.78
219.46
ng/l
—
9
69
15
138
1.10
0.06
1.1
5.8
202.20
230.61
u/l
2.09
15
129
68
664
1.05
0.06
4.9
10.4
4.20
4.09
e9/l
0.16
57
585
20
207
0.96
0.01
3.0
3.8
150.60
144.86
ng/l
0.02
20
169
56
567
0.98
0.01
4.1
6.4
1.22
1.21
mmol/l
0.77
48
485
17
174
0.97
0.00
1.5
2.0
31.76
29.62
s
0.47
17
168
25
252
0.99
0.00
1.1
1.8
459.55
454.77
pmol/l
0.04
20
210
45
446
1.01
0.00
1.8
2.0
84.27
95.37
pmol/l
0.94
20
222
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.1
—
221.71
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
14
140
1.00
-0.00
5.7
8.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.0
—
13.28
—
0
6
0
9
0.00
-0.00
0.0
4.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: MNMED_RILUZOLE – Use of riluzole
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).