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Benign neoplasm: Bronchus and lung

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_BRONCHUS_LUNG

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D14.3&
  • Hospital discharge: ICD-9 — 2123
  • Hospital discharge: ICD-8 — 2123
  • Cause of death: ICD-10 — D14.3&
  • Cause of death: ICD-9 — 2123
  • Cause of death: ICD-8 — 2123

2 out of 7 registries used, show all original rules.

464

4. Check minimum number of events

None

464

5. Include endpoints

None

464

6. Filter based on genotype QC (FinnGen only)

464

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D14
Name in latin
Neoplasma benignum bronchi

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3012 1351 1630
Only index persons 2312 1123 1189
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.05
Only index persons 0.04 0.04 0.05
Median age at first event (years)
Whole population 57.62 56.60 58.38
Only index persons 56.62 55.59 57.59

-FinnGen-

Key figures

All Female Male
Number of individuals 464 200 264
Unadjusted period prevalence (%) 0.10 0.07 0.12
Median age at first event (years) 58.26 54.61 61.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
414
Matched controls
4141
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D14.3
ICD-10 Finland
Benign neoplasm: Bronchus and lung
+∞
323.0
315
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
20.6
140.5
237
252
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
38.0
120.1
155
64
2123A
ICD-9 Finland
Benign neoplasm of respiratory and intrathoracic organs, Bronchus and lung
+∞
74.2
69
*
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
84.1
69.0
76
11
UGC12
NOMESCO Finland
Flexible bronchoscopy
7.5
45.1
118
209
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
401.3
37.6
37
*
GDA20
NOMESCO Finland
Excision of lesion of lung
134.9
35.3
37
*
21230
ICD-8 Finland
Benign neoplasm of respiratory system, Bronchus and lung
+∞
33.8
32
*
5823
FHL
Lung avobiopsy and wedge resection
126.9
22.8
24
*
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
13.2
18.4
32
26
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
49.6
16.1
19
*
7931A
ICD-9 Finland
Nonspecific abnormal findings on radiological and other examination of body structure, Lung field
34.9
15.9
20
6
GD1AD
NOMESCO Finland
Thorax CT examination
6.5
15.3
40
67
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.9
15.2
51
115
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
15.1
53
126
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
13.8
215
1347
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
19.0
13.5
20
11
5822
FHL
Exploratory thoracotomy and small procedure (eg lung suture)
72.1
12.7
14
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
6.1
12.5
34
60
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
8.6
12.2
26
32
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
11.7
90
390
WX402
NOMESCO Finland
General anaesthesia
2.7
11.7
87
370
1240
FHL
Bronchoscopy
10.5
11.1
21
21
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.3
10.4
38
94
GDC00
NOMESCO Finland
Lobectomy of lung
17.2
9.9
15
9
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
16.0
9.1
14
9
2391A
ICD-9 Finland
Neoplasm of unspecified nature, Respiratory system
37.5
9.1
11
*
N02AX02
ATC
tramadol; systemic, rectal
1.9
9.0
197
1338
WX250
NOMESCO Finland
Intercostal blockade
51.0
8.7
10
*
8240/3-C34.9
ICD-O-3
Neuroendocrine tumor, NOS, of lung, NOS
91.8
8.4
9
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.5
8.3
67
296
51925
ICD-8 Finland
Other diseases of respiratory system, Infiltratio pulmonis NUD
14.8
8.2
13
9
5188X
ICD-9 Finland
Other diseases of lung
17.6
8.1
12
7
5826
FHL
Lobectomy or bilobectomy
34.0
8.1
10
*
GDA10
NOMESCO Finland
Biopsy of lung
22.5
8.0
11
5
B01AB05
ATC
enoxaparin; parenteral
1.9
8.0
139
858
R05
ICD-10 Finland
Cough
2.2
7.8
88
456
N02BE01
ATC
paracetamol; systemic, rectal
2.1
7.5
347
2962
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.7
7.5
50
197
GDB10
NOMESCO Finland
Wedge resection of lung
81.4
7.4
8
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
3.3
7.3
35
111
23130
ICD-8 Finland
Neoplasm of unspecified nature of respiratory organs, Bronchus and lung
+∞
7.3
7
*
XG410
NOMESCO Finland
Flow-volume spirometry
3.9
7.2
28
75
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.0
7.0
40
143
D38.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Mediastinum
14.6
6.4
10
7
GD1AT
NOMESCO Finland
Biopsy of the lung with ultrasound guidance
18.3
6.3
9
5
D14.4
ICD-10 Finland
Benign neoplasm: Respiratory system, unspecified
+∞
6.3
6
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
6.2
54
248
R03BB04
ATC
tiotropium bromide; inhalant
2.3
6.1
56
261
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
6.1
113
707

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
31
53
6.20
17.67
1.3
1.7
45.3
16.3
ug/l
0.41
31
53
249
1584
2.23
16.01
10.4
8.9
1.3
1.2
inr
0.23
78
460
30
55
5.76
15.92
2.4
3.0
—
—
—
0
0
61
202
3.33
15.11
10.9
8.6
—
—
—
0
0
101
462
2.52
13.75
8.6
7.0
1.7
1.2
mmol/l
0.59
87
368
92
421
2.48
12.43
9.0
7.1
96.4
95.2
%
1.70
92
408
186
1207
1.90
9.91
4.9
5.5
—
—
—
0
0
95
484
2.21
9.89
1.4
1.3
—
—
—
0
0
81
386
2.33
9.88
10.1
7.4
124.7
120.8
g/l
0.98
81
375
232
1625
1.86
9.65
4.9
4.8
35.5
35.4
g/l
0.10
214
1522
210
1463
1.80
8.58
2.4
2.2
—
—
—
0
0
250
1852
1.76
8.12
5.1
5.6
1.8
1.9
e9/l
1.02
209
1637
289
2235
1.78
8.05
6.5
4.7
6.8
6.8
mmol/l
0.04
277
2100
229
1661
1.75
7.96
5.3
5.6
0.6
0.7
%
0.13
217
1551
253
1889
1.75
7.92
5.2
5.7
0.2
0.2
e9/l
0.31
214
1662
244
1811
1.73
7.74
5.1
5.5
0.6
0.6
e9/l
0.91
199
1571
232
1699
1.73
7.71
6.9
5.9
1.2
1.2
mmol/l
2.06
219
1533
245
1822
1.73
7.70
5.1
5.5
0.0
0.0
e9/l
0.13
202
1588
276
2127
1.73
7.58
7.7
9.1
4.4
4.1
e9/l
0.98
227
1874
233
1728
1.70
7.24
4.5
4.0
—
—
—
0
0
231
1711
1.70
7.20
5.6
5.6
2.8
2.9
%
0.24
219
1595
232
1722
1.69
7.17
5.5
5.6
58.7
57.4
%
1.02
221
1616
27
86
3.27
7.10
8.1
6.3
11.0
11.3
mmol/l
0.15
27
80
27
86
3.27
7.10
8.1
6.3
105.4
105.1
mmol/l
0.16
27
80
235
1753
1.69
7.10
5.9
5.8
26.1
27.2
%
0.86
223
1638
63
310
2.19
7.05
9.8
8.1
—
—
—
0
0
231
1720
1.68
6.99
5.9
5.9
8.9
8.8
%
0.23
219
1615
18
46
4.03
6.50
2.8
3.0
3.9
7.0
nmol/l
0.39
18
46
169
1179
1.68
6.41
2.6
2.3
—
—
—
0
0
161
1116
1.68
6.22
3.7
4.2
7.4
7.4
ph
0.35
38
205
55
272
2.16
6.08
1.6
1.4
—
—
—
0
0
242
1869
1.62
6.02
8.8
6.8
1.2
1.2
mmol/l
1.95
206
1569
343
2893
1.71
5.98
9.0
7.8
80.6
78.7
u/l
0.44
329
2706
54
272
2.12
5.70
5.9
4.4
—
—
—
0
0
316
2629
1.63
5.60
4.4
4.0
—
—
—
0
0
62
331
2.01
5.60
1.6
1.5
—
—
—
0
0
62
336
1.98
5.37
1.4
1.4
—
—
—
0
0
211
1613
1.57
5.25
11.4
9.8
0.0
0.0
e9/l
0.67
160
1342
18
55
3.36
5.08
2.1
2.7
—
—
—
0
0
36
163
2.31
4.92
7.7
4.9
1.0
0.9
%
0.72
36
155
24
89
2.79
4.92
1.6
2.0
134.4
126.7
g/l
0.46
14
65
22
78
2.91
4.88
2.5
3.9
2.4
2.5
mmol/l
0.12
16
51
36
164
2.30
4.86
7.8
4.9
2.0
1.6
%
1.42
36
156
21
74
2.92
4.72
2.2
2.4
16.4
16.1
%
0.06
12
41
249
2009
1.52
4.65
7.2
6.4
10.6
11.3
umol/l
0.85
241
1908
27
110
2.54
4.63
3.8
3.2
—
—
—
0
0
72
432
1.79
4.56
4.5
4.3
51.9
32.2
ug/l
0.17
64
363
52
282
1.95
4.50
3.7
4.3
0.0
0.1
%
0.66
15
75
52
289
1.90
4.19
3.3
4.0
0.5
0.4
%
0.26
14
70
54
304
1.88
4.19
3.6
4.2
0.1
0.2
%
0.69
17
91
21
80
2.70
4.12
2.5
3.0
—
—
—
0
0
47
260
1.90
3.85
9.1
6.9
25.3
24.5
mmol/l
1.16
47
245
56
328
1.80
3.84
3.6
4.1
0.4
0.9
%
1.15
18
103
39
204
2.00
3.76
1.4
1.2
187.0
210.6
u/ml
0.14
34
187
68
426
1.70
3.70
2.6
3.0
6.9
8.3
umol/l
0.52
58
372
144
1081
1.48
3.60
4.3
4.4
—
—
—
0
0
13
41
3.23
3.52
1.9
1.4
306.5
298.3
pmol/l
—
8
34
19
79
2.47
3.18
3.4
2.4
—
—
—
0
0
17
67
2.60
3.16
2.5
2.7
4.3
4.4
e9/l
0.07
17
67
17
69
2.52
2.99
2.5
3.2
56.7
57.5
%
0.08
17
69
10
30
3.38
2.92
1.6
1.2
—
—
—
0
0
309
2726
1.40
2.91
4.7
4.1
12.3
12.7
mm/h
0.17
291
2487
167
1337
1.39
2.83
4.6
3.9
141.4
113.7
e6/l
0.16
124
973
105
774
1.46
2.82
1.7
1.7
1.3
1.2
mg/l
0.10
81
613
17
72
2.41
2.75
1.6
1.6
2.5
4.8
iu/l
—
5
21
148
1167
1.39
2.73
4.2
3.4
681.6
117.6
e6/l
0.45
118
910
131
1013
1.41
2.70
3.8
3.2
—
—
—
0
0
8
19
4.27
2.69
2.4
4.3
59.9
95.0
nmol/l
—
8
19
107
800
1.44
2.66
4.7
4.7
—
—
—
0
0
106
808
1.40
2.35
3.0
2.7
5.9
4.2
e6/l
0.92
94
719
134
1063
1.37
2.34
4.0
3.3
0.5
0.5
e6/l
0.00
99
804
185
1543
1.33
2.32
4.4
3.8
27.6
45.4
ng/l
1.97
140
1135
71
505
1.48
2.28
2.6
2.5
23.3
22.3
%
0.22
61
437
100
764
1.39
2.19
2.9
2.9
556.1
568.9
mosm/kgh2o
0.20
84
647
10
37
2.74
2.11
3.7
2.8
—
—
—
0
0
148
1210
1.33
2.09
3.1
3.0
1128.9
1507.5
ng/l
1.11
131
1033
94
719
1.39
2.04
4.2
3.9
229.5
307.9
ng/l
0.23
77
584
149
1224
1.32
2.03
3.1
2.5
56.7
57.7
u/l
0.15
141
1133
46
313
1.52
1.84
3.1
3.9
1.2
1.2
mmol/l
0.11
41
270
40
264
1.56
1.83
4.2
3.2
7.4
7.4
ph
—
10
32
16
80
2.04
1.82
4.6
2.5
—
—
—
0
0
6
18
3.36
1.75
1.2
2.2
—
—
—
0
0
385
3625
1.36
1.75
21.7
15.1
25.0
24.2
mg/l
0.18
343
2907
45
311
1.49
1.69
3.7
3.8
—
—
—
0
0
63
465
1.41
1.69
1.2
1.3
616.0
526.4
titre
0.19
20
107
6
19
3.19
1.66
1.3
1.3
—
—
—
0
0
7
25
2.83
1.65
4.4
4.2
—
—
—
0
0
19
323
0.57
1.62
3.1
3.4
—
—
—
0
0
74
566
1.37
1.61
2.6
2.0
—
—
—
0
0
80
620
1.35
1.61
4.6
3.3
0.8
0.8
mmol/l
1.14
71
576
7
27
2.62
1.52
4.4
4.1
—
—
—
0
0
7
27
2.62
1.52
3.6
2.9
—
—
—
0
0
89
708
1.32
1.50
3.0
3.2
2.5
2.5
mmol/l
0.28
80
625
112
922
1.28
1.47
5.9
6.8
—
—
—
0
0
18
102
1.80
1.47
2.6
2.0
9.4
12.9
mg/l
1.08
18
94
6
22
2.75
1.44
1.0
1.2
—
—
—
0
0
5
17
2.96
1.36
1.2
1.0
—
—
—
0
0
58
444
1.35
1.28
1.4
1.3
—
—
—
0
0
397
3801
1.31
1.23
23.8
17.6
139.4
139.7
mmol/l
1.75
392
3699
10
50
2.02
1.17
2.1
1.5
—
—
—
0
0
10
50
2.02
1.17
2.1
1.5
—
—
—
0
0
10
50
2.02
1.17
2.1
1.5
—
—
—
0
0
10
50
2.02
1.17
2.1
1.5
—
—
—
0
0
12
65
1.87
1.14
4.4
3.0
0.9
0.9
nmol/l
0.06
12
51
397
3812
1.29
1.12
24.0
17.7
4.0
4.0
mmol/l
0.82
391
3706
7
32
2.21
1.08
2.0
1.4
—
—
—
0
0
13
216
0.59
1.07
1.3
1.2
—
—
—
0
0
142
1243
1.21
1.06
3.8
3.7
2.4
2.3
mmol/l
0.54
129
1087
12
67
1.81
1.05
1.1
1.4
—
—
—
0
0
9
46
1.98
1.04
1.0
1.3
—
—
—
0
0
338
3203
1.20
1.00
21.7
15.9
39.5
39.7
%
0.12
240
2197
129
1125
1.20
1.00
2.4
2.1
305.7
281.7
u/l
0.07
123
1057
5
23
2.19
0.98
1.2
1.4
1.0
1.0
g/l
—
5
23
163
1457
1.18
0.95
3.2
2.7
127.3
137.7
ug/l
0.28
156
1341
56
450
1.28
0.91
1.9
1.6
—
—
—
0
0
285
2673
1.17
0.91
4.0
3.7
14.9
14.8
pmol/l
0.08
256
2377
7
127
0.54
0.89
4.3
11.9
—
—
—
0
0
8
42
1.92
0.89
1.3
1.2
—
—
—
0
0
57
466
1.25
0.82
2.0
1.4
—
—
—
0
0
6
33
1.83
0.79
1.0
1.4
—
—
—
0
0
8
48
1.68
0.79
6.9
5.2
381.3
347.3
umol/l
—
8
42
14
90
1.57
0.79
1.4
1.6
—
—
—
0
0
19
268
0.70
0.79
1.4
1.4
—
—
—
0
0
0
28
0.00
0.76
0.0
1.3
—
22550.8
—
0
19
398
3861
1.22
0.75
12.8
10.9
26.6
26.4
u/l
0.07
388
3722
397
3856
1.20
0.70
24.1
18.0
79.1
80.6
umol/l
0.34
397
3856
14
204
0.68
0.70
2.1
2.4
—
—
—
0
0
7
42
1.68
0.68
1.3
1.1
—
—
—
0
0
29
371
0.77
0.67
7.7
4.3
—
—
—
0
0
44
359
1.25
0.67
5.1
3.8
0.8
2.1
mmol/l
0.71
33
286
18
129
1.41
0.64
1.5
3.7
49.1
113.5
mg/l
0.67
13
103
18
129
1.41
0.64
1.4
3.7
37.2
33.2
mg/l
0.15
13
106
52
437
1.21
0.61
1.5
1.7
—
—
—
0
0
8
50
1.61
0.61
1.0
1.3
0.6
0.5
nmol/l
—
8
45
7
114
0.61
0.58
1.3
1.1
—
—
—
0
0
70
801
0.85
0.58
4.3
4.1
1.0
1.0
kg/l
—
10
119
11
161
0.68
0.58
1.5
1.6
—
—
—
0
0
81
714
1.16
0.57
1.9
1.7
1114.3
1172.7
nmol/l
0.28
62
542
6
37
1.63
0.55
1.2
1.1
—
—
—
0
0
6
38
1.59
0.54
1.2
1.1
—
—
—
0
0
10
66
1.53
0.53
1.4
3.2
—
—
—
0
0
100
902
1.14
0.52
2.3
2.1
3.0
3.2
mg/l
0.24
87
779
6
40
1.51
0.51
1.2
1.3
—
—
—
0
0
40
336
1.21
0.49
2.3
2.5
77.1
69.0
e9/l
0.47
26
274
15
110
1.38
0.49
1.3
1.5
316.9
293.3
ug/g
—
8
67
7
45
1.56
0.49
4.1
3.6
—
—
—
0
0
7
47
1.50
0.47
1.6
1.7
—
—
—
0
0
108
987
1.12
0.46
3.7
3.4
—
—
—
0
0
8
121
0.66
0.46
8.1
4.1
—
—
—
0
0
5
84
0.59
0.46
1.0
1.3
—
—
—
0
0
67
594
1.15
0.45
1.3
1.3
78.3
39.2
iu/ml
0.41
19
193
120
1105
1.12
0.45
4.1
3.0
—
—
—
0
0
360
3690
0.89
0.45
5.3
5.2
2.7
2.7
mmol/l
0.14
331
3369
7
50
1.41
0.45
1.3
1.2
—
—
—
0
0
384
3753
1.13
0.45
19.6
14.5
—
—
—
0
0
109
1002
1.11
0.42
1.6
1.7
1.5
1.4
mmol/l
0.47
82
826
14
184
0.75
0.42
1.6
1.4
—
—
—
0
0
338
3284
1.11
0.42
4.9
4.5
1.8
2.0
mu/l
1.00
310
2936
5
33
1.52
0.41
1.0
1.2
—
—
—
0
0
7
102
0.68
0.40
1.0
1.1
—
—
—
0
0
366
3576
1.11
0.39
5.0
4.8
6.0
6.0
mmol/l
0.07
333
3240
11
80
1.38
0.38
1.4
2.1
—
—
—
0
0
5
76
0.65
0.36
1.2
1.2
2.4
12.7
e6/l
—
5
61
5
76
0.65
0.36
1.2
1.3
7.6
1600.3
e6/l
—
5
63
6
43
1.40
0.35
1.0
1.3
—
—
—
0
0
12
156
0.76
0.35
6.6
4.5
—
—
—
0
0
21
172
1.23
0.35
3.4
2.9
—
—
—
0
0
107
996
1.10
0.34
4.3
4.0
0.0
0.0
estimate
0.00
45
332
6
45
1.34
0.34
1.0
1.3
—
—
nmol/l
—
0
0
29
247
1.19
0.33
3.8
2.9
—
—
—
0
0
11
83
1.33
0.32
1.1
1.2
—
—
—
0
0
7
54
1.30
0.30
1.0
1.3
—
—
—
0
0
7
55
1.28
0.30
1.0
1.0
—
—
—
0
0
187
1791
1.07
0.30
5.2
5.0
0.0
0.0
estimate
0.00
48
342
8
107
0.74
0.29
1.5
2.9
1.4
1.6
mg/l
—
8
97
67
729
0.91
0.29
1.4
1.2
0.6
1.5
u/ml
1.69
23
202
8
63
1.27
0.28
1.1
1.3
—
—
—
0
0
100
940
1.08
0.26
1.4
1.3
—
—
—
0
0
5
72
0.69
0.26
1.0
1.2
—
—
—
0
0
6
83
0.72
0.24
1.7
1.3
—
—
—
0
0
355
3608
0.93
0.24
4.6
4.7
4.5
4.6
mmol/l
0.46
329
3318
12
97
1.24
0.23
1.3
4.1
—
—
—
0
0
353
3585
0.94
0.22
4.6
4.6
1.4
1.4
mmol/l
0.37
324
3279
184
1779
1.06
0.21
3.9
3.7
0.0
0.0
estimate
0.00
47
344
0
11
0.00
0.21
0.0
1.1
—
2.4
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.5
—
—
—
0
0
8
105
0.76
0.21
1.3
1.2
—
—
—
0
0
121
1156
1.06
0.21
3.5
3.3
31.5
222.3
mg/l
1.29
81
755
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
2.5
—
—
—
0
0
22
193
1.15
0.20
1.2
1.2
41.8
147.6
iu/ml
—
6
72
15
127
1.19
0.20
1.7
1.7
—
—
—
0
0
43
395
1.10
0.19
2.3
2.3
115.5
137.6
ug/g
0.36
32
318
104
992
1.06
0.19
2.8
2.8
8655.2
7575.4
umol/l
0.07
95
858
121
1160
1.06
0.19
5.7
4.0
—
—
—
0
0
22
194
1.14
0.19
4.8
3.4
—
—
—
0
0
40
367
1.10
0.18
1.3
1.6
—
—
—
0
0
75
793
0.94
0.18
2.2
1.8
398.1
6061035.9
pmol/l
0.50
63
660
7
58
1.21
0.18
2.3
2.7
—
—
—
0
0
99
945
1.06
0.18
2.7
3.1
0.6
0.8
ug/l
2.03
68
630
258
2526
1.05
0.18
4.7
4.3
—
—
—
0
0
403
3991
1.07
0.18
29.9
22.2
250.2
244.1
e9/l
1.09
395
3882
124
1193
1.05
0.17
3.4
3.1
7.6
7.7
mmol/l
0.12
102
987
403
3992
1.07
0.17
29.9
22.3
7.2
6.7
e9/l
2.45
393
3871
403
3992
1.07
0.17
29.9
22.2
4.5
4.5
e12/l
0.43
395
3874
165
1600
1.05
0.17
4.5
5.0
2.1
3.3
ug/l
1.48
148
1426
8
68
1.18
0.16
1.1
1.3
—
—
—
0
0
8
69
1.16
0.16
1.1
1.2
—
—
—
0
0
8
69
1.16
0.16
1.1
1.2
—
—
—
0
0
8
70
1.15
0.16
1.1
1.3
—
—
—
0
0
348
3437
1.05
0.15
6.1
6.1
40.8
40.6
mmol/mol
0.19
321
3187
156
1515
1.04
0.15
1.9
2.0
97.5
92.9
pmol/l
0.55
84
798
186
1814
1.04
0.15
4.0
3.7
0.0
0.0
estimate
0.50
42
329
7
89
0.78
0.14
1.1
1.4
1.1
0.9
nmol/l
—
7
75
22
242
0.90
0.13
1.0
1.2
—
—
—
0
0
247
2430
1.04
0.12
5.6
4.4
26.3
3240.1
e6/l
—
6
42
18
162
1.12
0.12
3.2
3.8
25.4
25.2
mmol/l
0.08
18
150
344
3473
0.96
0.11
4.1
4.2
1.3
1.3
mmol/l
0.04
310
3158
81
838
0.96
0.10
3.9
3.7
—
—
—
0
0
30
282
1.07
0.09
1.3
2.3
—
—
—
0
0
17
185
0.92
0.08
1.7
1.3
—
—
—
0
0
36
342
1.06
0.08
1.2
1.6
—
—
—
0
0
5
65
0.77
0.08
1.0
1.5
—
—
—
0
0
14
127
1.11
0.08
2.6
3.2
0.3
0.2
g/l
—
9
48
19
204
0.93
0.07
4.2
3.5
—
—
—
0
0
12
132
0.91
0.06
1.5
2.0
37.3
37.5
g/l
0.04
12
113
36
376
0.95
0.06
1.4
1.5
—
—
—
0
0
51
493
1.04
0.06
1.3
1.2
—
—
—
0
0
56
577
0.97
0.06
1.3
1.3
17.6
15.1
u/ml
0.10
17
224
16
149
1.08
0.05
1.4
1.8
—
—
—
0
0
17
159
1.07
0.05
1.3
1.3
—
—
—
0
0
11
120
0.91
0.05
2.8
1.7
29.1
21.0
s
0.67
11
110
12
129
0.93
0.03
1.4
1.5
—
—
—
0
0
128
1266
1.02
0.03
3.0
3.0
—
—
—
0
0
21
201
1.05
0.03
1.2
1.5
—
—
—
0
0
15
143
1.05
0.01
2.2
1.9
1401.4
599.2
ug/l
0.28
15
135
123
1221
1.01
0.01
4.2
4.0
6.7
8.1
mg/mmol
0.21
84
783
20
206
0.97
0.00
1.2
1.3
—
—
—
0
0
24
246
0.97
0.00
5.0
3.1
123.8
128.1
g/l
0.38
24
241
14
137
1.02
0.00
1.0
1.1
—
—
—
0
0
90
902
1.00
0.00
1.7
1.6
18.6
20.5
nmol/l
0.72
81
757
35
349
1.00
0.00
2.4
2.6
6.4
8.3
ug/l
0.52
30
307
67
669
1.00
0.00
1.4
1.3
2.4
2.6
g/l
0.54
49
399
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
17.8
—
0
7
6
62
0.97
0.00
1.2
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.5
—
40.0
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
10
100
1.00
0.00
1.1
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
0.00
1.4
1.7
—
—
—
0
0
6
61
0.98
0.00
1.2
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
7.6
—
0
5
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
7.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_BRONCHUS_LUNG and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_BRONCHUS_LUNG 1.748 [1.41, 2.17] < 0.001
Birth year 0.993 [0.98, 1.0] 0.142

During the follow-up period (1.1.1998 — 31.12.2019), 137 out of 715 females with CD2_BENIGN_BRONCHUS_LUNG died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_BRONCHUS_LUNG 1.92 [1.6, 2.3] < 0.001
Birth year 0.992 [0.98, 1.0] 0.072

During the follow-up period (1.1.1998 — 31.12.2019), 241 out of 829 males with CD2_BENIGN_BRONCHUS_LUNG died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_BRONCHUS_LUNG.

N-year risk Females Males
1 0.114% 0.359%
5 0.91% 2.593%
10 2.427% 6.229%
15 4.365% 11.649%
20 8.005% 19.781%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_BRONCHUS_LUNG – Benign neoplasm: Bronchus and lung

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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