Benign neoplasm: Respiratory system, unspecified

CD2_BENIGN_RESPIRATORY_NOS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D14.4& Hospital discharge: ICD-8 — 21299 Cause of death: ICD-10 — D14.4& Cause of death: ICD-8 — 21299 2 out of 7 registries used, show all original rules.	76
4. Check minimum number of events None	76
5. Include endpoints None	76
6. Filter based on genotype QC (FinnGen only)	76

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D14
Name in latin: Neoplasma benignum organi respiratorii non specificati

NAME	CD2_BENIGN_RESPIRATORY_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D144
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	21299
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D144
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	21299
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Respiratory system, unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Benign neoplasm: Respiratory system, unspecified

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	588	308	276
Only index persons	477	253	224
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	53.81	51.97	55.67
Only index persons	51.51	50.21	52.97

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	76	36	40
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	52.19	44.26	59.32

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
68: Matched controls
682

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D14.4

ICD-10 Finland

Benign neoplasm: Respiratory system, unspecified

+∞

75.8

21299

ICD-8 Finland

Benign neoplasm of respiratory system, Unspecified site

+∞

10.7

DQB10

NOMESCO Finland

Endoscopic excision of lesion of larynx

44.5

6.9

R91

ICD-10 Finland

Abnormal findings on diagnostic imaging of lung

6.3

6.4

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3021589) Normoblasts [#/volume] in Blood

255

2.58

3.96

10.6

11.9

0.0

e9/l

0.50

206

(40758558) Short blood count panel - Blood

145

2.62

3.77

4.5

5.8

—

(3001604) Monocytes [#/volume] in Blood

298

2.51

3.66

5.3

5.4

0.6

e9/l

0.17

258

(3006315) Basophils [#/volume] in Blood

300

2.49

3.58

5.3

5.4

0.0

e9/l

0.53

259

(3023368) Bacteria identified in Blood by Culture

162

2.28

2.85

6.7

4.6

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

346

2.17

2.62

8.1

10.2

3.9

4.4

e9/l

0.84

304

(3021788) Differential panel - Synovial fluid

7.54

2.59

1.0

1.3

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.78

2.58

6.0

3.0

24.3

24.1

mmol/l

—

(3022621) pH of Urine by Test strip

3.24

2.52

2.4

2.3

—

(42870588) Differential panel, method unspecified - Blood

188

2.10

2.43

7.2

5.2

—

(3012544) pH of Venous blood

2.65

2.27

4.8

3.5

—

(4010399)

2.82

2.21

1.4

—

(40768804) Tissue Pathology biopsy report

239

1.96

2.14

2.9

2.1

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

4.24

2.08

2.0

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.41

2.03

1.9

1.6

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.95

2.01

21.0

4.7

23.7

24.5

mmol/l

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

4.78

1.97

2.0

2.5

6.5

4.4

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

4.78

1.97

2.2

2.5

61.0

61.6

—

(3029937) Albumin [Presence] in Urine by Test strip

158

1.98

1.96

3.1

4.3

0.0

estimate

—

(3042936) Bacteria identified in Isolate by Culture

2.24

1.92

1.9

2.2

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

3.74

1.87

1.8

1.7

—

(3000991) Gas panel - Venous blood

2.51

1.80

20.8

4.7

—

(3021601) Nitrite [Presence] in Urine by Test strip

297

1.83

1.78

3.8

6.1

0.0

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

299

1.81

1.73

3.1

4.3

0.0

estimate

—

(3002582) Erythrocytes [#/volume] in Urine

192

1.83

1.66

3.1

3.0

12.6

399.4

e6/l

0.59

145

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.31

1.65

5.1

3.5

5.5

5.6

kpa

0.11

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.74

1.64

1.0

1.6

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.21

1.60

1.6

1.8

—

(3013290) Carbon dioxide [Partial pressure] in Blood

3.49

1.55

1.6

3.1

4.6

5.0

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

3.49

1.55

1.6

3.1

7.8

8.3

kpa

—

(3024354) Oxygen [Partial pressure] in Venous blood

2.35

1.47

2.8

3.2

4.9

4.6

kpa

—

(3019060) Gas panel - Arterial blood

2.41

1.46

1.6

3.9

—

(3035350) Ketones [Presence] in Urine by Test strip

301

1.69

1.43

3.1

4.2

0.0

estimate

—

(3037467) Urinalysis macro (dipstick) panel - Urine

401

1.72

1.40

4.0

4.7

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

2.29

1.39

4.8

4.1

113.0

74.9

ng/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.07

1.31

4.7

4.3

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

135

1.77

1.29

1.8

1.6

2.2

1.4

mg/l

0.23

106

(3045414) Leukocytes [Presence] in Urine

2.52

1.27

1.3

1.5

—

(3003396) Base excess in Arterial blood by calculation

2.04

1.26

16.4

6.0

2.5

0.9

mmol/l

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.00

1.21

1.7

1.9

—

(3028026) IgM [Mass/volume] in Serum or Plasma

2.17

1.19

1.3

1.7

1.2

1.1

g/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

218

1.62

1.17

3.4

3.0

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

564

1.85

1.13

18.6

14.3

80.6

81.1

ml/min/173m2

0.05

457

(40761511) CBC panel - Blood by Automated count

628

2.07

1.12

18.0

14.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.47

1.11

1.4

1.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.47

1.11

1.4

1.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.81

1.10

1.7

2.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

231

1.58

1.08

3.2

4.5

—

(3005719) IgG [Mass/volume] in Serum or Plasma

2.04

1.07

1.4

2.0

11.5

10.5

g/l

—

(3025941) Bacteria identified in Stool by Culture

2.16

1.06

2.1

1.6

—

(3018418) pH of Serum or Plasma

162

1.60

1.00

5.9

3.9

7.4

—

(3026008) Bacteria identified in Urine by Culture

180

1.58

1.00

3.2

—

(3010813) Leukocytes [#/volume] in Blood

660

2.15

0.98

29.3

21.4

6.9

6.7

e9/l

0.16

642

(3026361) Erythrocytes [#/volume] in Blood

660

2.15

0.98

29.2

21.2

4.6

4.5

e12/l

0.19

642

(36304419) Bacteria [Presence] in Urine

163

1.59

0.98

3.3

2.5

—

(3032080) INR in Blood by Coagulation assay

239

1.50

0.90

4.9

7.0

1.0

1.2

inr

2.07

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.08

0.89

1.3

1.7

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.01

0.86

1.5

1.1

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.78

0.83

1.8

1.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

169

1.52

0.83

2.8

4.2

—

(3018095) Leukocytes [#/volume] in Urine

224

1.48

0.82

3.8

3.7

44.1

67.7

e6/l

0.31

154

(3037121) Protein [Mass/volume] in Urine

0.00

0.80

0.0

3.1

—

0.1

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.83

0.78

2.2

1.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.83

0.78

1.3

1.9

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

593

1.66

0.77

21.7

14.9

28.4

23.4

mg/l

0.58

471

(40768797) Stomach Pathology biopsy report

1.64

0.75

1.2

—

(3003327) Ova and parasites identified in Stool by Light microscopy

2.07

0.74

2.0

1.5

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.07

0.74

3.2

6.2

—

(3007164) IgA [Mass/volume] in Serum or Plasma

120

1.54

0.72

1.4

1.5

1.9

2.8

g/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

103

1.57

0.72

2.5

1.9

—

(3013512) EKG study

184

1.44

0.70

3.1

4.5

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.77

0.65

2.8

1.9

—

(3030467) Casts [#/volume] in Urine by Automated count

178

1.42

0.63

3.3

2.7

0.2

0.4

e6/l

0.27

131

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.71

0.62

1.0

1.3

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.71

0.62

1.0

1.3

4.0

3.9

g/l

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.71

0.62

1.0

1.3

8.7

7.6

g/l

—

(3000492) Spirometry study

1.57

0.61

1.3

1.4

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

143

1.44

0.60

1.3

1.2

1.0

u/ml

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

108

1.48

0.59

1.6

1.3

37.0

43.5

iu/ml

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.67

0.57

2.2

4.2

0.2

e6/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

238

1.35

0.56

4.1

4.4

19.3

46.9

ng/l

1.31

168

(3019150) Specific gravity of Urine by Refractometry

127

1.44

0.56

3.6

3.9

1.0

kg/l

—

(3044889) 12 lead EKG panel

416

1.34

0.54

4.3

3.9

—

(3000330) Specific gravity of Urine by Test strip

1.58

0.54

1.7

6.0

—

(3022145) Colonoscopy Study observation

1.55

0.54

1.7

1.3

—

(1761868) Lipid panel - Serum or Plasma

238

0.73

0.50

2.2

3.1

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

634

1.48

0.48

23.0

16.8

91.0

77.4

umol/l

0.48

634

(40761536) Microorganisms panel - Urine sediment

1.44

0.46

4.3

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.49

0.44

7.5

7.0

—

(4035726)

1.42

0.43

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.37

0.42

2.3

2.1

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

3.5

—

107.0

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

3.5

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

3.5

—

4.0

—

(4094501)

0.00

0.41

0.0

1.2

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.41

0.0

1.4

—

(3016879) Cocaine [Presence] in Urine

0.00

0.41

0.0

1.4

—

(3027008) Opiates [Presence] in Urine

0.00

0.41

0.0

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.41

0.0

1.4

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.41

0.0

4.6

—

102.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

277

1.27

0.40

5.4

3.5

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.40

0.0

1.1

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.40

0.0

1.3

—

(40768793) Breast Pathology biopsy report

0.00

0.40

0.0

1.3

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.42

0.39

4.6

3.3

133.4

130.8

g/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.43

0.36

1.8

1.5

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.39

0.35

1.2

1.9

0.2

g/l

—

(3002256) Pathology report gross observation

1.38

0.32

1.3

1.2

—

(3000494) Fungus identified in Specimen by Culture

1.38

0.32

1.2

1.4

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

103

1.32

0.30

5.1

2.9

496.4

87.0

ng/l

—

(3015736) pH of Urine

236

1.22

0.30

2.9

4.0

—

(3044640) Blood type and Crossmatch panel - Blood

180

1.23

0.28

2.7

1.9

—

(3009542) Hematocrit [Volume Fraction] of Blood

540

1.22

0.26

22.4

14.3

39.8

40.2

0.11

389

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.32

0.25

9.7

3.6

1.3

1.0

mmol/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.27

0.23

2.2

3.0

0.2

3.3

e6/l

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

242

1.18

0.22

4.8

2.7

190.4

108.4

ug/l

0.58

219

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.4

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.3

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.1

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.21

0.0

1.1

—

110.9

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

4.3

—

86.8

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.1

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

2.2

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.26

0.20

1.4

1.5

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.7

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.20

0.0

1.3

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.0

—

2.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

557

1.17

0.18

4.4

4.7

1.8

2.0

mu/l

0.48

497

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.14

0.16

1.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

192

1.13

0.12

5.2

4.4

21.0

21.4

0.03

(3004588) Protein electrophoresis panel - Serum or Plasma

1.15

0.10

1.0

1.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.10

0.09

2.3

1.7

—

(40760892) CBC W Ordered Manual Differential panel - Blood

156

1.12

0.09

3.5

4.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.10

0.08

1.7

1.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.08

0.08

1.7

1.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

377

1.07

0.06

3.9

3.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

129

0.92

0.04

2.6

1.8

—

(3003694) ABO and Rh group [Type] in Blood

157

0.94

0.01

1.3

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.07

0.01

1.9

1.6

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.02

0.00

4.6

2.6

0.8

mmol/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

242

0.99

0.00

2.5

1.9

90.5

93.9

pmol/l

0.18

128

(3011397) Hemoglobin [Presence] in Urine by Test strip

137

1.03

0.00

3.6

3.9

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

0.0

1.4

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

0.0

2.0

—

34.3

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.4

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.1

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.3

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

90.8

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

4.4

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

1.8

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

0.0

1.5

—

187.5

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.0

1.2

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

6.3

—

142.7

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

14.0

—

(3020630) Protein [Mass/volume] in Serum or Plasma

0.94

0.00

1.2

1.9

72.0

67.3

g/l

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

14.2

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

10.1

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.92

0.00

1.6

1.4

—

(4268621)

0.00

0.0

1.9

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

0.0

4.2

—

20.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

1.3

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

226.8

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

0.0

1.4

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.2

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(4027681)

0.00

0.0

1.0

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

218.5

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

3.0

—

4.5

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3037556) Urate [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

0.0

1.7

—

6.3

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.4

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.0

1.0

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.3

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

0.0

4.4

—

51.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

(4306422)

0.00

0.0

1.1

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.0

1.4

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.0

2.4

—

13.7

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.0

1.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.2

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.5

—

(3012441) Differential panel - Pleural fluid

0.00

0.0

2.2

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RESPIRATORY_NOS and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_RESPIRATORY_NOS	1.947 [1.32, 2.87]	< 0.001
Birth year	0.987 [0.98, 1.0]	0.006

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 183 males with CD2_BENIGN_RESPIRATORY_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RESPIRATORY_NOS.

N-year risk	Females	Males
1	No data	0.295%
5	No data	2.14%
10	No data	5.616%
15	No data	10.662%
20	No data	17.775%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RESPIRATORY_NOS – Benign neoplasm: Respiratory system, unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Respiratory system, unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints