Benign neoplasm: Respiratory system, unspecified

CD2_BENIGN_RESPIRATORY_NOS

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D14.4& Hospital discharge: ICD-8 — 21299 Cause of death: ICD-10 — D14.4& Cause of death: ICD-8 — 21299 2 out of 7 registries used, show all original rules.	79
4. Check minimum number of events None	79
5. Include endpoints None	79
6. Filter based on genotype QC (FinnGen only)	74

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D14
Name in latin: Neoplasma benignum organi respiratorii non specificati

NAME	CD2_BENIGN_RESPIRATORY_NOS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D144
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	21299
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D144
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	21299
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm: Respiratory system, unspecified based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	588	308	276
Only index persons	477	253	224
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	53.81	51.97	55.67
Only index persons	51.51	50.21	52.97

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	74	37	37
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	55.63	51.98	59.28

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
79: Matched controls
790

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D14.4

ICD-10 Finland

Benign neoplasm: Respiratory system, unspecified

+∞

89.3

21299

ICD-8 Finland

Benign neoplasm of respiratory system, Unspecified site

+∞

11.7

R91

ICD-10 Finland

Abnormal findings on diagnostic imaging of lung

6.5

10.5

B97.7

ICD-10 Finland

Papillomavirus as the cause of diseases classified to other chapters

113.0

9.6

DHB10

NOMESCO Finland

Excision of lesion of internal nose

+∞

8.5

DQB10

NOMESCO Finland

Endoscopic excision of lesion of larynx

88.0

7.6

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40758558) Short blood count panel - Blood

154

2.67

4.10

4.3

5.8

—

(3021589) Normoblasts [#/volume] in Blood

266

2.48

3.79

10.4

11.7

0.00

e9/l

0.50

213

(3001604) Monocytes [#/volume] in Blood

313

2.36

3.36

5.3

5.5

0.57

0.59

e9/l

0.14

271

(3006315) Basophils [#/volume] in Blood

314

2.35

3.32

5.3

5.4

0.05

0.04

e9/l

0.39

271

(40768804) Tissue Pathology biopsy report

249

2.12

2.70

2.8

2.1

—

(3021788) Differential panel - Synovial fluid

7.52

2.58

1.0

1.3

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.77

2.57

6.0

3.0

24.33

24.19

mmol/l

—

(3023368) Bacteria identified in Blood by Culture

168

2.15

2.55

6.7

4.5

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.90

2.49

17.2

3.8

1.40

1.46

mmol/l

0.10

(3013650) Neutrophils [#/volume] in Blood by Automated count

361

2.05

2.38

7.9

10.1

3.86

4.34

e9/l

0.77

317

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

3.75

2.34

23.3

6.3

25.01

23.94

mmol/l

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

650

3.18

2.16

22.7

15.8

3.99

mmol/l

0.06

634

(3019550) Sodium [Moles/volume] in Serum or Plasma

647

3.27

2.16

22.1

15.9

139.58

139.70

mmol/l

0.16

631

(4200892) Spirometry reversibility

2.74

2.11

1.4

—

(3012544) pH of Venous blood

2.53

2.11

4.8

3.6

—

(3022621) pH of Urine by Test strip

2.86

2.09

2.4

2.2

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.97

1.97

2.0

1.3

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.85

1.93

21.0

4.6

23.66

24.56

mmol/l

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

3.73

1.87

1.8

1.7

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

4.37

1.85

2.0

2.5

6.47

4.31

e9/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

4.37

1.85

2.2

2.5

61.00

60.75

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.25

1.77

1.9

1.6

—

(3000991) Gas panel - Venous blood

2.45

1.72

20.8

4.7

—

(3029937) Albumin [Presence] in Urine by Test strip

165

1.86

1.69

3.1

4.3

0.00

estimate

—

(40760892) CBC W Ordered Manual Differential panel - Blood

291

1.76

1.65

7.1

6.2

—

(3042936) Bacteria identified in Isolate by Culture

2.08

1.65

1.9

2.1

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.74

1.64

1.0

1.6

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.20

1.59

1.6

1.8

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.26

1.59

5.1

3.5

5.54

5.59

kpa

0.08

(3024354) Oxygen [Partial pressure] in Venous blood

2.34

1.47

2.8

3.2

4.93

4.64

kpa

—

(3021601) Nitrite [Presence] in Urine by Test strip

308

1.69

1.46

3.8

6.1

0.00

estimate

—

(3013290) Carbon dioxide [Partial pressure] in Blood

3.26

1.46

1.6

3.0

4.56

5.02

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

3.26

1.46

1.6

3.0

7.76

8.24

kpa

—

(3019060) Gas panel - Arterial blood

2.35

1.42

1.6

3.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

418

1.71

1.42

3.9

4.7

—

(3009261) Glucose [Presence] in Urine by Test strip

310

1.67

1.41

3.1

4.3

0.00

estimate

—

(3002582) Erythrocytes [#/volume] in Urine

200

1.71

1.40

3.1

12.58

383.95

e6/l

0.59

151

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.00

1.21

4.6

4.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.00

1.21

1.7

1.9

—

(3045414) Leukocytes [Presence] in Urine

2.41

1.21

1.3

1.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

591

1.88

1.18

17.9

14.1

80.93

81.49

ml/min/173m2

0.06

478

(3003396) Base excess in Arterial blood by calculation

1.96

1.16

16.4

6.0

2.24

0.87

mmol/l

—

(3028026) IgM [Mass/volume] in Serum or Plasma

2.11

1.16

1.3

1.7

1.16

1.15

g/l

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

139

1.70

1.16

1.8

1.6

2.25

1.39

mg/l

0.23

110

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.38

1.13

2.0

1.7

—

(40761511) CBC panel - Blood by Automated count

655

2.12

1.11

17.4

13.9

—

(3035350) Ketones [Presence] in Urine by Test strip

314

1.55

1.10

3.1

4.2

0.00

estimate

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

2.13

1.09

4.8

3.9

113.00

73.93

ng/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.78

1.06

1.7

2.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.36

1.05

1.4

1.1

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.36

1.05

1.4

1.1

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.99

1.05

1.4

2.0

11.48

10.44

g/l

—

(3018418) pH of Serum or Plasma

170

1.59

1.02

5.7

3.8

7.42

7.41

—

(3037121) Protein [Mass/volume] in Urine

0.00

1.00

0.0

3.0

—

0.13

—

(3000963) Hemoglobin [Mass/volume] in Blood

689

2.17

0.98

28.5

21.2

135.04

136.25

g/l

0.24

680

(3026361) Erythrocytes [#/volume] in Blood

689

2.17

0.98

28.2

21.1

4.55

4.52

e12/l

0.25

670

(3009542) Hematocrit [Volume Fraction] of Blood

689

2.17

0.98

28.2

20.9

40.70

40.30

0.27

655

(3010813) Leukocytes [#/volume] in Blood

689

2.17

0.98

28.3

21.3

6.83

6.73

e9/l

0.15

670

(3007461) Platelets [#/volume] in Blood

689

2.17

0.98

28.3

21.1

230.72

248.85

e9/l

1.92

675

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

226

1.53

0.97

3.4

3.1

—

(3025941) Bacteria identified in Stool by Culture

1.98

0.96

2.0

1.5

—

(3013512) EKG study

192

1.53

0.91

3.0

4.4

—

(3026008) Bacteria identified in Urine by Culture

193

1.52

0.89

3.2

3.3

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

240

1.48

0.87

3.2

4.5

—

(36304419) Bacteria [Presence] in Urine

169

1.51

0.82

3.3

2.6

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.74

0.81

1.8

1.5

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.88

0.81

1.5

1.1

—

(3013707) Erythrocyte sedimentation rate by Westergren method

471

1.46

0.79

4.3

4.0

13.80

11.70

mm/h

0.26

426

(46235355) HIV 1 and 2 tests - Meaningful Use set

109

1.59

0.78

2.7

1.9

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.83

0.78

2.2

1.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.92

0.76

2.1

1.8

—

(3000492) Spirometry study

1.62

0.73

1.2

1.4

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.98

0.72

3.2

6.2

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.91

0.69

2.0

1.4

—

(3041096) Erythrocytes [Presence] in Urine by Automated

175

1.44

0.69

2.8

4.2

—

(3044889) 12 lead EKG panel

427

1.39

0.67

4.2

3.8

—

(3019150) Specific gravity of Urine by Refractometry

131

1.48

0.67

3.5

3.9

1.02

kg/l

—

(3018095) Leukocytes [#/volume] in Urine

232

1.40

0.66

3.8

44.07

75.54

e6/l

0.44

159

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.77

0.65

2.8

1.9

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

150

1.45

0.64

1.3

1.2

1.05

1.02

u/ml

—

(40768797) Stomach Pathology biopsy report

1.55

0.63

1.2

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.71

0.62

1.0

1.3

—

(40768793) Breast Pathology biopsy report

0.00

0.61

0.0

1.3

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

621

1.52

0.60

21.1

14.8

29.07

23.01

mg/l

0.76

494

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.59

0.60

6.9

6.8

—

(1761868) Lipid panel - Serum or Plasma

244

0.71

0.59

2.2

3.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

127

1.43

0.55

1.4

1.94

2.82

g/l

—

(3000330) Specific gravity of Urine by Test strip

1.58

0.54

1.7

6.0

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.58

0.54

2.2

4.4

0.21

0.19

e6/l

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

467

1.33

0.52

3.5

4.1

14.86

14.87

pmol/l

0.01

416

(3030467) Casts [#/volume] in Urine by Automated count

184

1.35

0.51

3.3

2.8

0.25

0.35

e6/l

0.26

135

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

112

1.42

0.49

1.6

1.3

36.67

43.46

iu/ml

—

(4035726) Immunohistochemistry procedure

1.37

0.42

1.4

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.41

0.0

3.5

—

4.01

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.41

0.0

1.3

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.41

0.0

3.5

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.41

0.0

3.5

—

107.00

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.41

0.0

4.6

—

102.06

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.40

0.0

1.2

—

(3027008) Opiates [Presence] in Urine

0.00

0.40

0.0

1.4

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.40

0.0

1.4

—

(3016879) Cocaine [Presence] in Urine

0.00

0.40

0.0

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.40

0.0

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.41

0.40

2.1

2.2

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

248

1.27

0.40

4.1

4.3

19.41

45.46

ng/l

1.29

176

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.39

0.0

1.1

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.39

0.0

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.40

0.34

1.8

1.5

—

(3022145) Colonoscopy Study observation

1.38

0.34

1.7

1.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

292

1.22

0.33

2.7

2.2

—

(40761536) Microorganisms panel - Urine sediment

1.38

0.32

4.3

4.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.31

0.28

1.7

1.5

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

663

1.32

0.28

22.5

16.7

90.42

76.72

umol/l

0.50

663

(3002256) Pathology report gross observation

1.34

0.27

1.3

1.2

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

632

1.27

0.26

5.0

2.76

2.68

mmol/l

0.28

574

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

106

1.27

0.25

5.1

2.9

496.43

84.85

ng/l

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

1.37

0.24

4.6

3.2

133.40

131.14

g/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

582

1.21

0.23

4.3

4.8

1.83

2.00

mu/l

0.42

520

(3000494) Fungus identified in Specimen by Culture

1.30

0.23

1.2

1.4

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.30

0.23

9.7

3.7

1.27

1.02

mmol/l

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

1.23

0.22

5.0

2.6

5.00

4.79

kpa

—

(3022217) INR in Platelet poor plasma by Coagulation assay

291

1.17

0.22

8.2

13.3

1.16

1.21

inr

0.14

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

4.1

—

80.50

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.21

0.0

1.1

—

110.91

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.3

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.3

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.1

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.21

0.0

2.2

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.8

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

1.27

0.21

1.2

1.9

0.20

0.22

g/l

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.7

—

(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.0

—

2.20

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.22

0.17

2.1

1.6

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.22

0.17

1.6

1.8

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

102

1.21

0.16

2.2

2.9

0.20

3.16

e6/l

—

(3044640) Blood type and Crossmatch panel - Blood

190

1.14

0.14

2.7

1.9

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

388

1.12

0.14

4.0

3.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

137

0.85

0.13

2.6

1.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

192

1.13

0.12

5.2

4.4

21.03

21.36

0.03

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

597

0.89

0.11

5.8

6.0

39.46

40.53

mmol/mol

0.45

555

(3004588) Protein electrophoresis panel - Serum or Plasma

1.15

0.10

1.0

1.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

258

0.95

0.02

2.5

1.9

90.50

96.39

pmol/l

0.34

134

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.02

0.00

1.9

1.6

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

102

0.98

0.00

4.6

2.6

0.82

0.81

mmol/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

142

0.98

0.00

3.6

3.9

—

(3003694) ABO and Rh group [Type] in Blood

164

0.97

0.00

1.3

1.4

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.98

0.00

2.3

1.8

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.4

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.2

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

5.7

—

128.86

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.87

-0.00

1.6

1.3

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

196.29

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.01

-0.00

1.3

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

4.4

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

226.83

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

-0.00

0.0

1.0

—

90.75

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.2

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

-0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

2.0

—

34.29

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

4.2

—

20.02

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

13.74

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

1.4

—

(3013727) Leukocytes other/100 leukocytes in Blood

0.00

-0.00

0.0

4.4

—

51.00

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

1.4

—

7.18

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.3

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.2

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

10.13

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

215.29

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

14.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3020630) Protein [Mass/volume] in Serum or Plasma

0.94

-0.00

1.2

1.9

72.02

67.27

g/l

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

1.5

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.2

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

0.00

-0.00

0.0

1.4

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.0

—

4.48

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.3

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.7

—

6.33

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

14.2

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

1.2

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

2.2

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

1.9

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

1.7

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction

0.00

-0.00

0.0

1.5

—

187.50

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RESPIRATORY_NOS and mortality.

Females

No data

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_RESPIRATORY_NOS	1.947 [1.32, 2.87]	< 0.001
Birth year	0.987 [0.98, 1.0]	0.006

During the follow-up period (1.1.1998 — 31.12.2019), 58 out of 183 males with CD2_BENIGN_RESPIRATORY_NOS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RESPIRATORY_NOS.

N-year risk	Females	Males
1	No data	0.295%
5	No data	2.14%
10	No data	5.616%
15	No data	10.662%
20	No data	17.775%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RESPIRATORY_NOS – Benign neoplasm: Respiratory system, unspecified

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm: Respiratory system, unspecified

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints