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This is a non-core endpoint: only basic statistics are computed.

Exposure to excessive natural heat

VWXY20_EXPOS_EXCESSI_NATURAL_HEAT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 X30
  • Cause of death: ICD-10 X30

2 out of 7 registries used, show all original rules.

77

4. Check minimum number of events

None

77

5. Include endpoints

None

77

6. Filter based on genotype QC (FinnGen only)

77

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
X30-X39

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 77 38 39
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 62.87 65.41 60.40

-FinnGen-

Age distribution of first events

010203040506070800246810121416AgeIndividuals

-FinnGen-

Year distribution of first events

197019751980198519901995200520102015202020230246810121416182022242628YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
68
Matched controls
682
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
X30
ICD-10 Finland
Exposure to excessive natural heat
+∞
94.8
67
*
T67.0
ICD-10 Finland
Heatstroke and sunstroke
+∞
14.0
13
*
T67.3
ICD-10 Finland
Heat exhaustion, anhydrotic
+∞
9.6
9
*
F20.9
ICD-10 Finland
Schizophrenia, unspecified
28.8
7.8
10
*
N05AH02
ATC
clozapine; systemic
34.0
7.3
9
*
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
8.2
6.1
13
19

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
44
171
4.67
10.32
5.6
4.7
—
—
—
0
0
13
26
5.81
6.48
7.4
8.2
—
—
—
0
0
19
54
4.34
6.36
7.3
7.9
120.42
121.83
g/l
0.10
19
54
37
185
2.92
5.04
3.9
3.5
—
—
—
0
0
32
150
2.94
4.87
2.4
2.0
2.90
3.19
mg/l
0.26
27
129
21
90
2.83
3.64
3.0
1.9
—
—
—
0
0
15
53
3.27
3.60
3.1
3.2
57.53
70.52
e9/l
—
9
42
8
14
6.23
3.44
8.4
8.2
1.20
1.05
mmol/l
—
8
14
59
426
2.65
3.30
5.0
4.4
—
—
—
0
0
8
19
4.57
2.76
2.8
3.0
—
—
—
0
0
6
10
6.40
2.75
9.5
8.2
10.33
10.50
mmol/l
—
6
10
6
10
6.40
2.75
9.7
8.2
103.50
104.40
mmol/l
—
6
10
11
39
3.12
2.60
6.0
6.1
22.41
24.54
mmol/l
0.45
11
39
14
58
2.73
2.54
9.1
7.1
—
—
—
0
0
5
8
6.59
2.41
1.0
1.9
—
—
—
0
0
8
23
3.76
2.34
7.6
4.7
1.94
1.43
%
—
8
23
8
23
3.76
2.34
7.6
4.8
1.13
0.87
%
—
8
23
17
81
2.41
2.34
1.1
1.3
—
—
—
0
0
43
297
2.01
2.33
7.0
6.1
0.04
0.04
e9/l
0.32
38
256
43
297
2.01
2.33
7.0
6.1
0.57
0.61
e9/l
0.91
38
256
43
299
1.99
2.26
9.3
6.3
1.18
1.21
mmol/l
2.16
35
238
32
201
2.01
2.24
7.4
5.5
—
—
—
0
0
43
301
1.97
2.20
7.0
6.1
1.88
1.80
e9/l
0.26
37
267
43
303
1.95
2.14
10.1
6.5
0.16
0.18
e9/l
0.28
38
264
14
65
2.41
2.03
6.4
4.4
—
—
—
0
0
25
150
1.99
1.95
3.1
3.5
73.88
83.58
mg/l
0.06
19
98
38
263
1.88
1.94
5.2
5.0
33.28
35.52
g/l
1.52
38
245
7
23
3.24
1.85
1.4
1.2
—
—
—
0
0
70
614
2.54
1.82
29.4
17.6
4.02
4.00
mmol/l
0.21
70
596
12
222
0.46
1.72
2.3
2.9
—
—
—
0
0
58
474
1.91
1.62
7.7
7.9
82.36
78.29
u/l
0.22
53
441
10
44
2.46
1.61
7.2
4.6
—
—
—
0
0
25
162
1.80
1.51
3.1
4.5
6.87
11.88
mg/mmol
0.48
19
105
28
189
1.76
1.48
6.4
4.0
7.44
7.41
ph
—
7
46
33
234
1.72
1.46
2.6
2.0
91.33
88.47
pmol/l
0.10
20
115
21
130
1.85
1.46
1.7
1.7
882.38
1206.04
nmol/l
1.20
16
100
7
29
2.55
1.43
3.1
2.2
—
—
—
0
0
14
76
2.03
1.41
2.4
1.6
—
—
—
0
0
23
151
1.75
1.32
1.9
1.9
—
—
—
0
0
21
135
1.76
1.29
3.3
3.4
509.50
547.52
mosm/kgh2o
0.54
14
118
12
64
2.04
1.26
1.2
1.4
—
—
—
0
0
12
66
1.97
1.17
7.2
4.3
1.31
1.98
mmol/l
—
7
53
45
363
1.58
1.12
28.4
9.6
4.50
4.30
e9/l
0.24
40
318
29
213
1.58
1.07
4.3
3.7
40.98
32.96
e6/l
0.11
24
172
26
187
1.59
1.04
2.1
2.3
—
—
—
0
0
13
77
1.83
1.03
1.3
1.7
—
—
—
0
0
70
642
1.99
0.99
24.6
13.7
—
—
—
0
0
33
256
1.51
0.93
3.4
4.2
21.41
48.87
ng/l
1.06
25
194
8
44
1.91
0.89
1.0
1.1
—
—
—
0
0
25
185
1.52
0.87
4.6
3.3
—
—
—
0
0
13
193
0.61
0.84
4.9
3.4
—
—
—
0
0
20
142
1.55
0.83
3.3
3.3
—
—
—
0
0
22
160
1.52
0.83
1.3
1.5
—
—
—
0
0
32
252
1.46
0.82
10.0
8.8
1.36
1.21
inr
—
9
87
5
23
2.25
0.77
3.0
1.7
—
—
—
0
0
18
128
1.53
0.74
1.3
1.6
—
—
—
0
0
5
27
1.91
0.70
6.6
1.4
—
—
—
0
0
30
241
1.40
0.67
5.1
4.2
225.57
68.49
e6/l
0.35
24
185
5
28
1.84
0.67
6.6
1.5
—
—
—
0
0
5
28
1.84
0.67
6.6
1.5
—
—
—
0
0
5
29
1.77
0.65
6.6
1.5
—
—
—
0
0
22
168
1.43
0.65
19.0
6.7
—
—
—
0
0
25
196
1.41
0.64
4.6
3.5
0.74
0.43
e6/l
0.22
19
154
8
51
1.63
0.63
1.4
1.2
—
—
—
0
0
0
21
0.00
0.61
0.0
6.7
—
—
—
0
0
61
559
1.44
0.58
37.2
15.3
40.19
40.34
%
0.06
43
412
60
549
1.42
0.57
5.2
4.6
1.74
1.91
mu/l
0.76
55
501
14
103
1.44
0.49
1.3
1.5
—
—
—
0
0
17
215
0.73
0.47
4.1
4.9
1.21
1.78
ug/l
0.62
17
189
7
49
1.47
0.47
2.4
2.9
62.33
66.38
g/l
—
7
43
61
566
1.37
0.47
5.3
4.3
5.99
5.92
mmol/l
0.15
55
511
0
15
0.00
0.41
0.0
2.3
—
3.83
—
0
6
46
416
1.26
0.40
4.8
3.9
—
—
—
0
0
7
53
1.35
0.32
1.7
1.9
—
—
—
0
0
8
63
1.30
0.29
2.0
1.5
—
—
—
0
0
49
456
1.21
0.28
3.9
3.8
14.94
14.80
pmol/l
0.12
41
410
8
66
1.24
0.28
1.4
1.3
—
—
—
0
0
5
39
1.30
0.23
2.0
3.6
0.05
0.14
e6/l
—
5
39
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
4.08
—
0
12
0
12
0.00
0.21
0.0
1.8
—
9.06
—
0
12
0
12
0.00
0.21
0.0
2.0
—
107.42
—
0
12
0
14
0.00
0.20
0.0
4.6
—
22.80
—
0
8
20
176
1.18
0.20
4.4
4.2
—
—
—
0
0
24
216
1.16
0.18
2.1
2.0
—
—
—
0
0
8
68
1.20
0.17
2.1
1.5
—
—
—
0
0
6
77
0.76
0.16
1.2
1.2
—
—
—
0
0
5
43
1.17
0.10
8.4
4.6
136.00
82.17
ng/l
—
5
38
5
45
1.12
0.10
3.8
1.9
—
—
—
0
0
5
48
1.04
0.09
2.8
2.1
—
—
—
0
0
6
54
1.12
0.09
2.2
3.4
—
—
—
0
0
5
64
0.77
0.08
9.0
3.3
—
—
—
0
0
7
63
1.12
0.08
1.1
1.4
—
—
—
0
0
17
182
0.92
0.06
5.5
3.6
0.00
0.00
estimate
—
7
67
15
139
1.10
0.06
1.1
1.3
2.71
2.35
g/l
—
6
91
31
322
0.94
0.05
4.4
3.6
0.00
0.00
estimate
—
7
70
32
327
0.96
0.01
4.4
3.6
0.00
0.00
estimate
—
7
66
25
248
1.01
0.00
4.7
3.6
—
—
—
0
0
30
295
1.03
0.00
17.7
10.1
0.00
0.00
e9/l
0.00
22
240
14
145
0.96
0.00
6.0
6.1
—
—
—
0
0
0
8
0.00
0.00
0.0
4.8
—
3.39
—
0
8
0
8
0.00
0.00
0.0
2.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
1.2
1.3
—
—
—
0
0
32
320
1.00
0.00
5.2
5.1
0.00
0.00
estimate
—
7
70
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
10.67
—
0
6
0
6
0.00
0.00
0.0
11.5
—
0.62
—
0
6
0
6
0.00
0.00
0.0
4.3
—
32.18
—
0
6
0
6
0.00
0.00
0.0
4.5
—
129.67
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_EXPOS_EXCESSI_NATURAL_HEAT – Exposure to excessive natural heat

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).