Exposure to excessive natural heat

VWXY20_EXPOS_EXCESSI_NATURAL_HEAT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — X30 Cause of death: ICD-10 — X30 2 out of 7 registries used, show all original rules.	80
4. Check minimum number of events None	80
5. Include endpoints None	80
6. Filter based on genotype QC (FinnGen only)	80

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 5
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: X30-X39

NAME	VWXY20_EXPOS_EXCESSI_NATURAL_HEAT
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	X30
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	X30
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Exposure to excessive natural heat based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	80	41	39
Unadjusted period prevalence (%)	0.02	0.01	0.02
Median age at first event (years)	63.54	66.53	60.40

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
80: Matched controls
800

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

X30

ICD-10 Finland

Exposure to excessive natural heat

+∞

112.2

T67.0

ICD-10 Finland

Heatstroke and sunstroke

153.0

12.8

T67.3

ICD-10 Finland

Heat exhaustion, anhydrotic

+∞

11.7

AA1AD

NOMESCO Finland

CT of head and brain

3.5

6.7

140

T67.5

ICD-10 Finland

Heat exhaustion, unspecified

75.6

6.5

N05AH02

ATC

clozapine; systemic

20.0

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3023368) Bacteria identified in Blood by Culture

176

4.56

10.39

5.5

4.7

—

(3026008) Bacteria identified in Urine by Culture

194

3.28

6.40

3.9

3.6

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

4.06

5.88

7.3

7.5

120.42

123.02

g/l

0.19

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

5.76

4.88

7.4

8.2

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

157

2.88

4.85

2.5

2.0

2.90

3.23

mg/l

0.31

132

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

3.34

4.81

2.0

1.7

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

3.18

4.29

2.0

1.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

105

2.84

4.02

2.0

1.9

—

(3037467) Urinalysis macro (dipstick) panel - Urine

442

2.79

3.70

5.5

4.5

—

(3023520) Reticulocytes [#/volume] in Blood

3.25

3.59

3.1

57.53

70.52

e9/l

—

(3047181) Lactate [Moles/volume] in Blood

6.21

3.43

8.4

8.2

1.20

1.05

mmol/l

—

(3042936) Bacteria identified in Isolate by Culture

2.71

3.40

3.0

1.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

277

2.31

3.31

2.5

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

7.99

3.11

1.0

1.9

—

(3052851) Hemolysis interference index of Serum or Plasma

4.69

3.10

2.7

2.9

—

(3000991) Gas panel - Venous blood

2.90

2.99

8.6

7.0

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.44

2.92

5.7

6.1

22.62

24.54

mmol/l

0.43

(3039000) Anion gap in Blood

6.38

2.75

9.5

8.2

10.33

10.50

mmol/l

—

(3018572) Chloride [Moles/volume] in Blood

6.38

2.75

9.7

8.2

103.50

104.40

mmol/l

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

313

2.11

2.67

9.0

6.2

1.19

1.21

mmol/l

1.27

252

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

5.00

2.66

1.0

1.1

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.54

2.62

1.9

1.7

—

(3001604) Monocytes [#/volume] in Blood

307

2.06

2.56

6.8

6.1

0.56

0.61

e9/l

1.16

265

(3006315) Basophils [#/volume] in Blood

307

2.06

2.56

6.8

6.2

0.04

e9/l

0.28

265

(3019198) Lymphocytes [#/volume] in Blood

312

2.01

2.40

6.9

6.2

1.86

1.81

e9/l

0.15

276

(3013115) Eosinophils [#/volume] in Blood

313

2.00

2.36

9.8

6.5

0.17

0.18

e9/l

0.22

272

(3007930) Methemoglobin/Hemoglobin.total in Blood

3.74

2.34

7.6

4.8

1.12

0.87

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

3.74

2.34

7.6

4.7

1.94

1.43

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

273

1.93

2.17

5.1

4.9

33.54

35.52

g/l

1.33

255

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

3.73

2.11

2.0

1.5

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

3.73

2.11

2.0

1.5

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

5.25

2.10

1.0

1.9

—

(3000494) Fungus identified in Specimen by Culture

2.27

2.09

1.1

1.3

—

(3019309) Folate [Moles/volume] in Red Blood Cells

131

2.06

1.7

852.65

1197.09

nmol/l

1.38

101

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

3.17

1.99

1.0

1.1

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

199

1.91

1.98

2.8

3.3

2666.50

1940.98

ng/l

0.18

160

(40760892) CBC W Ordered Manual Differential panel - Blood

289

1.86

1.96

7.9

7.2

—

(3012516) Albumin [Mass/volume] in Urine

158

1.96

1.94

3.0

3.4

73.88

85.05

mg/l

0.07

104

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

493

2.00

1.86

7.7

7.8

82.23

78.30

u/l

0.23

458

(3023103) Potassium [Moles/volume] in Serum or Plasma

641

2.58

1.81

29.4

17.5

4.01

3.99

mmol/l

0.23

623

(3018418) pH of Serum or Plasma

196

1.85

1.79

6.2

3.9

7.44

7.40

—

(3022217) INR in Platelet poor plasma by Coagulation assay

305

1.79

1.77

25.6

15.6

1.39

1.24

inr

0.43

(3024891) Influenza virus A+B Ag [Presence] in Specimen

3.09

1.76

1.4

1.2

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

139

1.92

1.73

1.9

2.1

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.66

1.65

3.1

2.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

245

1.76

1.64

2.6

2.0

91.32

89.17

pmol/l

0.07

119

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.45

1.63

1.0

1.6

—

(1761868) Lipid panel - Serum or Plasma

230

0.48

1.62

2.2

2.9

—

(3044640) Blood type and Crossmatch panel - Blood

193

1.79

1.61

2.0

2.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

159

1.83

1.60

2.0

1.9

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.16

1.54

1.2

1.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

170

1.78

1.52

3.0

4.1

6.87

12.37

mg/mmol

0.55

111

(3026782) Osmolality of Urine

145

1.82

1.51

3.2

3.7

531.31

531.91

mosm/kgh2o

0.01

127

(3019060) Gas panel - Arterial blood

2.34

1.47

7.2

4.4

—

(3002032) Base excess in Venous blood by calculation

2.09

1.43

6.8

4.3

1.24

2.01

mmol/l

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.06

1.38

1.4

1.5

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

3.06

1.38

2.6

2.5

4.12

3.61

g/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

266

1.64

1.33

3.6

4.3

21.10

47.52

ng/l

1.06

202

(3045414) Leukocytes [Presence] in Urine

2.62

1.33

3.0

1.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.96

1.31

2.4

1.6

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.89

1.30

1.0

1.1

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.99

1.28

1.2

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

224

1.63

1.23

4.6

3.6

39.41

31.88

e6/l

0.11

180

(3013650) Neutrophils [#/volume] in Blood by Automated count

377

1.60

1.21

27.4

9.5

4.38

4.31

e9/l

0.08

331

(3011397) Hemoglobin [Presence] in Urine by Test strip

146

1.70

1.20

3.7

3.3

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

248

1.56

1.10

4.3

3.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

124

1.70

1.09

2.5

1.6

—

(36304419) Bacteria [Presence] in Urine

194

1.59

1.08

4.9

3.2

—

(36660697) Celiac disease serology panel - Serum

2.03

1.06

1.1

—

(3003694) ABO and Rh group [Type] in Blood

170

1.59

1.01

1.3

1.5

—

(3041096) Erythrocytes [Presence] in Urine by Automated

201

0.58

0.98

4.9

3.6

—

(40761511) CBC panel - Blood by Automated count

670

2.02

0.98

24.7

13.8

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

2.23

0.94

1.0

1.1

—

(3027944) Amphetamines [Presence] in Urine

2.08

0.89

5.7

1.5

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

114

1.62

0.88

4.5

3.2

6.80

1.65

e6/l

—

(3000764) Benzodiazepines [Presence] in Urine

2.01

0.86

5.7

1.5

—

(3027008) Opiates [Presence] in Urine

2.01

0.86

5.7

1.5

—

(3028300) Cannabinoids [Presence] in Urine

1.94

0.83

5.7

1.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

108

1.60

0.81

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

134

1.55

0.81

1.4

1.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.68

0.81

1.3

1.7

—

(3030467) Casts [#/volume] in Urine by Automated count

206

1.47

0.80

4.9

3.4

0.76

0.43

e6/l

0.24

160

(3018095) Leukocytes [#/volume] in Urine

253

1.44

0.79

5.4

4.1

208.56

66.40

e6/l

0.34

192

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.72

0.77

1.6

1.9

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

218

1.44

0.75

2.0

3.7

2.28

2.37

mmol/l

3.41

189

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.73

0.70

1.4

2.3

—

(40758558) Short blood count panel - Blood

175

1.44

0.69

18.3

6.6

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.61

0.0

1.4

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.60

0.0

7.7

—

(4200892) Spirometry reversibility

1.53

0.59

1.4

1.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

578

1.42

0.58

5.3

4.7

1.77

1.93

mu/l

0.69

528

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

126

1.44

0.58

4.5

2.8

0.71

0.97

e6/l

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.67

0.57

1.0

—

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

1.61

0.50

6.3

4.4

119.29

79.94

ng/l

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

594

1.39

0.49

5.5

4.3

5.96

5.91

mmol/l

0.11

534

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

408

1.30

0.49

3.5

3.2

—

(3044889) 12 lead EKG panel

429

1.30

0.48

5.0

3.9

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.47

0.48

2.8

2.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

268

0.75

0.47

4.8

3.8

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

215

0.73

0.47

4.1

4.9

1.21

1.78

ug/l

0.62

189

(3016879) Cocaine [Presence] in Urine

1.65

0.44

6.2

1.5

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.41

0.0

4.6

—

22.04

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.41

0.0

1.7

—

(3017044) Thyrotropin receptor Ab [Units/volume] in Serum

0.00

0.41

0.0

2.2

—

3.83

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.50

0.41

1.4

2.2

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.39

0.40

3.8

2.3

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.46

0.40

1.2

1.3

—

(3000492) Spirometry study

1.39

0.40

2.0

1.5

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

1.50

0.37

1.8

3.5

0.04

0.13

e6/l

—

(3013512) EKG study

185

1.26

0.34

4.3

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

481

1.23

0.33

3.9

14.86

14.79

pmol/l

0.06

433

(3020630) Protein [Mass/volume] in Serum or Plasma

1.41

0.32

2.4

2.8

62.33

66.67

g/l

—

(40768804) Tissue Pathology biopsy report

225

1.23

0.31

2.3

2.0

—

(3019225) pH of Specimen

1.27

0.30

2.1

3.6

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

609

1.25

0.28

20.2

14.5

80.20

81.33

ml/min/173m2

0.11

501

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.30

0.27

6.4

7.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.26

0.26

2.0

1.5

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

632

1.25

0.26

4.8

4.5

2.62

2.71

mmol/l

0.45

571

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.37

0.24

1.4

1.5

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

15.73

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.21

0.0

2.3

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.2

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.3

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

9.06

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.21

0.0

2.5

—

107.15

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.21

0.0

2.5

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.21

0.0

2.5

—

4.05

—

(3022621) pH of Urine by Test strip

1.24

0.20

3.8

1.8

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.20

0.0

2.1

—

271.41

—

(40761536) Microorganisms panel - Urine sediment

0.74

0.17

9.0

3.4

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.20

0.17

1.8

2.0

26.88

29.75

u/l

—

(3002256) Pathology report gross observation

1.12

0.16

1.4

1.3

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.16

0.16

2.6

4.1

—

(3022145) Colonoscopy Study observation

1.08

0.08

1.1

1.4

—

(21494755) Public health laboratory ask at order entry panel

1.03

0.08

1.1

1.3

—

(3007164) IgA [Mass/volume] in Serum or Plasma

149

1.09

0.06

1.3

2.59

2.34

g/l

—

(3029937) Albumin [Presence] in Urine by Test strip

188

0.95

0.02

5.3

3.7

0.00

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

332

1.04

0.02

5.6

5.2

0.00

estimate

—

(3002385) Erythrocyte distribution width [Ratio]

552

0.99

0.00

44.6

18.4

14.92

14.43

0.30

546

(3009261) Glucose [Presence] in Urine by Test strip

339

1.01

0.00

4.7

3.7

0.00

estimate

—

(3021589) Normoblasts [#/volume] in Blood

305

1.03

0.00

17.4

10.3

0.00

e9/l

-0.00

249

(3035350) Ketones [Presence] in Urine by Test strip

335

0.97

0.00

4.5

3.7

0.00

estimate

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

0.0

4.6

—

75.00

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

0.0

4.8

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.4

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.1

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.0

3.1

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

4.8

—

3.39

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

3.7

—

14.24

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.0

4.0

—

113.43

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.0

2.6

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.6

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

2.6

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.3

—

(4146454) Self-monitoring of blood glucose

0.00

0.0

2.6

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

2.3

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(3047189) Immunofixation for 24 hour Urine

0.00

0.0

1.2

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3004451) EKG impression Narrative

0.00

0.0

1.4

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.0

1.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.9

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

4.1

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

2.1

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.0

1.4

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

0.0

1.6

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.2

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.02

-0.00

2.8

2.1

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

11.5

—

0.62

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

1.7

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.8

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

2.8

—

(40768797) Stomach Pathology biopsy report

0.99

-0.00

1.1

1.2

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.5

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.2

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

180.13

—

(3000034) Microalbumin [Mass/volume] in Urine

0.00

-0.00

0.0

4.3

—

32.18

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(4035726) Immunohistochemistry procedure

0.85

-0.00

1.0

1.3

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

-0.00

0.0

2.0

—

7.28

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: VWXY20_EXPOS_EXCESSI_NATURAL_HEAT – Exposure to excessive natural heat

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Exposure to excessive natural heat

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Exposure to excessive natural heat (VWXY20_EXPOS_EXCESSI_NATURAL_HEAT)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints