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Disorders of magnesium metabolism

DOID Endpoint Browser PheWeb

E4_MG_MET

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — E83.4
  • Hospital discharge: ICD-9 — 2752
  • Cause of death: ICD-10 — E83.4
  • Cause of death: ICD-9 — 2752

2 out of 7 registries used, show all original rules.

271

4. Check minimum number of events

None

271

5. Include endpoints

None

271

6. Filter based on genotype QC (FinnGen only)

268

Control definitions (FinnGen only)

Control exclude
E4_METABOLIA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E83
Name in latin
Perturbationes metabolismi magnesii

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1471 688 778
Only index persons 1406 660 746
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.02
Only index persons 0.03 0.02 0.03
Median age at first event (years)
Whole population 64.94 65.77 64.25
Only index persons 65.12 66.02 64.32

-FinnGen-

Key figures

All Female Male
Number of individuals 268 119 149
Unadjusted period prevalence (%) 0.06 0.04 0.07
Median age at first event (years) 67.16 63.81 69.83

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
271
Matched controls
2710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E83.4
ICD-10 Finland
Disorders of magnesium metabolism
+∞
307.7
271
*
E87.6
ICD-10 Finland
Hypokalaemia
217.8
99.9
98
7
E83.51
ICD-10 Finland
Hypocalcemia
1290.6
96.1
88
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
8.0
63.4
123
254
TPX10
NOMESCO Finland
Implantation of vascular injection port
18.0
62.2
54
37
WW500
NOMESCO Finland
Blood transfusion
12.6
47.9
51
49
N02AA05
ATC
oxycodone; systemic
6.1
47.1
118
302
130
Kela drug reimbursment
Malignant tumour
6.9
45.0
87
173
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
8.8
45.0
65
94
C03CA01
ATC
furosemide; systemic
5.5
43.7
140
439
N17.9
ICD-10 Finland
Acute renal failure, unspecified
15.5
43.5
40
30
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.9
42.3
103
254
D64.9
ICD-10 Finland
Anaemia, unspecified
7.0
41.5
77
146
JN3AD
NOMESCO Finland
Abdominal CT examination
6.8
41.4
79
154
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
62.8
41.1
47
9
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.7
39.8
51
63
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.3
37.9
78
163
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
8.0
37.3
57
87
AA1AD
NOMESCO Finland
CT of head and brain
4.9
37.2
129
422
JN4AD
NOMESCO Finland
Body CT examination
6.0
36.7
80
176
R11
ICD-10 Finland
Nausea and vomiting
7.3
36.6
62
106
TPH07
NOMESCO Finland
Cathetrisation of artery
6.2
36.5
76
160
R56.8
ICD-10 Finland
Other and unspecified convulsions
10.0
36.3
45
53
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.7
35.5
152
580
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.6
34.8
140
508
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
7.7
34.8
55
87
A03FA01
ATC
metoclopramide; systemic, rectal
4.7
34.5
121
395
E86
ICD-10 Finland
Volume depletion
124.7
31.4
33
*
H02AB02
ATC
dexamethasone; systemic
5.1
31.2
84
220
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
9.4
31.2
40
49
Z51.5
ICD-10 Finland
Palliative care
6.2
31.1
62
124
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
11.0
31.0
35
36
TPH04
NOMESCO Finland
Cathetrisation of vein
4.4
30.5
110
362
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
7.9
29.4
44
65
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
9.0
28.9
38
48
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
10.9
28.2
32
33
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
8.2
27.9
40
56
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
27.6
187
941
ZXD05
NOMESCO Finland
Urgent procedure
4.0
27.3
126
488
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.6
25.9
57
124
SPAT1262
SPAT
Handing over of treatment supplies
4.2
25.5
88
276
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.9
25.4
110
405
A04AA02
ATC
granisetron; systemic, transdermal
5.8
25.3
52
106
E83.39
ICD-10 Finland
Other disorder of phosphorus metabolism
+∞
24.3
23
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
7.1
23.9
39
63
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.6
22.8
28
32
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
9.6
22.8
28
32
B01AB10
ATC
tinzaparin; parenteral
4.5
22.1
65
179
WZC00
NOMESCO Finland
Treatment plan or consultation
3.4
22.0
142
662
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.3
21.4
66
188
JN4BD
NOMESCO Finland
Extensive body CT
4.2
20.3
66
195
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.2
20.3
47
106
E61.2
ICD-10 Finland
Magnesium deficiency
+∞
20.0
19
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.1
19.9
47
108
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.4
19.5
95
368
A11CC03
ATC
alfacalcidol; systemic
20.6
19.1
28
15
J01MA12
ATC
levofloxacin; systemic
3.5
18.8
87
326
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
4.9
18.6
45
105
B03BA03
ATC
hydroxocobalamin; parenteral
6.1
18.4
34
62
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
7.9
18.1
26
36
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.7
18.1
69
227
UJF32
NOMESCO Finland
Coloscopy
3.1
17.7
109
482
GD1AD
NOMESCO Finland
Thorax CT examination
5.3
17.7
39
84
XX3DW
NOMESCO Finland
Time consuming IT work
3.8
17.7
66
214
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.3
17.4
50
134
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.1
17.0
97
409
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
5.2
16.9
38
83
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
16.8
101
438
SPAT1255
SPAT
Intravenous administration of medicine
5.1
16.7
38
84
205
Kela drug reimbursment
Chronic hypertension
3.1
16.1
96
413
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
6.4
16.1
28
48
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.3
16.0
46
123
E87.5
ICD-10 Finland
Hyperkalaemia
64.0
16.0
18
*
WZC30
NOMESCO Finland
Teaching
3.2
15.7
77
295
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.0
15.6
51
150
JAH00
NOMESCO Finland
Laparotomy
7.5
15.5
23
33
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
3.0
15.4
97
429
M04AA01
ATC
allopurinol; systemic
3.4
14.7
62
216
EBA15
NOMESCO Finland
Extraction of multiple teeth
6.5
14.6
25
42
A28
ICPC
Limited function/disability NOS
3.4
14.5
62
218
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
6.1
14.4
26
46
N07BB01
ATC
disulfiram; oral
5.4
14.4
30
61
SPAT1254
SPAT
Administration of medicine
3.5
14.3
59
202
A41.9
ICD-10 Finland
Sepsis, unspecified
6.0
14.1
26
47
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
21.5
14.0
20
10
T36
ICD-10 Finland
Poisoning by systemic antibiotics
6.7
14.0
23
37
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.7
13.8
114
575
R79.0
ICD-10 Finland
Abnormal level of blood mineral
+∞
13.7
13
*
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.8
13.4
46
139
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.6
13.4
50
160
I10
ICD-10 Finland
Essential (primary) hypertension
2.8
13.4
195
1291
C03DA01
ATC
spironolactone; oral
3.6
13.4
49
155
F10.25
ICD-10 Finland
Alcohol dependence continuous use
16.1
13.3
21
14
M10.9
ICD-10 Finland
Gout, unspecified
4.3
13.3
37
96
WX408
NOMESCO Finland
General anesthesy, balanced
2.7
13.2
97
459
D07AA02
ATC
hydrocortisone; topical
3.3
12.9
56
198
C07AB07
ATC
bisoprolol; oral
2.6
12.8
158
958
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.6
12.8
47
149
N02AX02
ATC
tramadol; systemic, rectal
2.5
12.8
145
845
D70.82
ICD-10 Finland
Drug-induced neutropenia
14.1
12.7
21
16
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
25.8
12.6
17
7
JFB00
NOMESCO Finland
Partial resection of small intestine
12.5
12.6
22
19
E83.50
ICD-10 Finland
Hypercalcemia
136.0
12.5
13
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.5
12.5
25
49
N06AX11
ATC
mirtazapine; oral
2.6
12.5
110
568
A02BC02
ATC
pantoprazole; systemic
2.9
12.4
212
1495
C08CA01
ATC
amlodipine; oral
2.5
12.3
130
729
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
28.2
12.2
16
6
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
28.2
12.2
16
6
WX892
NOMESCO Finland
Monitored bed care
4.1
12.1
36
98
R50.9
ICD-10 Finland
Fever, unspecified
3.2
12.1
57
211
L01BC06
ATC
capecitabine; oral
4.6
11.9
30
72
ZX095
NOMESCO Finland
Combined chemoradiotherapy
17.4
11.8
18
11
H02AB06
ATC
prednisolone; systemic
2.5
11.8
154
946
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
5.6
11.8
23
44
I50.9
ICD-10 Finland
Heart failure, unspecified
3.3
11.6
48
164
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.4
11.6
46
153
V03AE01
ATC
polystyrene sulfonate; oral
26.3
11.3
15
6
K08.3
ICD-10 Finland
Retained dental root
4.1
11.2
33
89
T90
ICPC
Diabetes non-insulin dependent
2.6
11.1
86
414
A04AA01
ATC
ondansetron; systemic, rectal
3.5
11.0
42
136
N19
ICD-10 Finland
Unspecified kidney failure
9.1
10.8
22
26
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
3.7
10.7
36
107
ZXE00
NOMESCO Finland
One hour or less
2.4
10.7
124
715
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
15.0
10.6
17
12
B81
ICPC
Anaemia vit B12/folate deficiency
5.8
10.6
20
37
WX402
NOMESCO Finland
General anaesthesia
2.6
10.5
76
352
WF049
NOMESCO Finland
Radiotherapy of metastasis
4.9
10.5
24
53
B01AB05
ATC
enoxaparin; parenteral
2.4
10.5
110
606
A10AE04
ATC
insulin glargine; parenteral
3.7
10.4
35
104
NF1AA
NOMESCO Finland
Hip X-ray examination
3.6
10.3
37
115
WX872
NOMESCO Finland
Intensive care
4.4
10.2
27
67
SPAT1229
SPAT
Assessment of need for aid
3.9
10.1
31
86
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
15.4
10.1
16
11
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
15.4
10.1
16
11
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
2.9
10.1
56
226
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
10.0
131
789
A10BA02
ATC
metformin; oral
2.4
9.9
94
492
N30.0
ICD-10 Finland
Acute cystitis
3.0
9.9
50
191
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
21.0
9.9
14
7
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
4.2
9.8
27
69
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
8.3
9.8
21
27
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.5
9.7
35
109
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
9.6
9.7
19
21
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
5.4
9.5
19
37
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.9
9.5
52
208
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
5.0
9.5
21
45
A10BB12
ATC
glimepiride; oral
4.0
9.4
28
76
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
7.8
9.4
21
29
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
9.4
97
526
E0000UV, ,
ATC
2.2
9.3
124
747
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
8.8
9.2
19
23
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.8
9.2
29
82
R53
ICD-10 Finland
Malaise and fatigue
2.5
9.2
74
359
JDB10
NOMESCO Finland
Percutaneous gastrostomy
10.6
9.2
17
17
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.3
9.1
37
124
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
9.1
46
176
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.5
9.0
66
306
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
9.1
8.9
18
21
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
9.1
8.9
18
21
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.8
8.9
52
215
A04AA55
ATC
palonosetron, combinations; systemic
4.5
8.8
22
52
N03AX14
ATC
levetiracetam; systemic
8.1
8.8
19
25
F05.9
ICD-10 Finland
Delirium, unspecified
14.7
8.8
14
10
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
14.7
8.8
14
10
B03XA02
ATC
darbepoetin alfa; parenteral
8.7
8.7
18
22
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.9
8.7
44
168
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
3.4
8.7
33
106
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
9.5
8.7
17
19
F10.40
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without seizures
17.0
8.6
13
8
XCK10
NOMESCO Finland
Photography of fundus of eye
3.3
8.6
35
118
C02AC05
ATC
moxonidine; oral
4.7
8.5
20
45
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.5
8.5
31
97
R4190
NOMESCO Finland
Nutritional therapy
4.9
8.5
19
41
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
9.0
8.4
17
20
F10.20
ICD-10 Finland
Alcohol dependence currently independent
7.5
8.4
19
27
H02AB09
ATC
hydrocortisone; systemic
11.3
8.4
15
14
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
9.9
8.4
16
17
A06AD11
ATC
lactulose; oral
2.8
8.3
46
185
P15
ICPC
Chronic alcohol abuse
4.8
8.3
19
42
J01MA02
ATC
ciprofloxacin; systemic
2.1
8.2
121
748
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
8.6
8.2
17
21
S01.0
ICD-10 Finland
Open wound of scalp
3.3
8.2
32
105
A02BC05
ATC
esomeprazole; systemic
2.1
8.1
124
776
K70.1
ICD-10 Finland
Alcoholic hepatitis
34.5
8.1
10
*
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
7.6
8.1
18
25
K92.1
ICD-10 Finland
Melaena
3.8
8.1
25
70
SPAT1263
SPAT
Sampling
2.1
8.0
123
771
A46
ICD-10 Finland
Erysipelas
2.6
8.0
51
220
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
4.9
8.0
18
39
SPAT1301
SPAT
No procedures
2.2
7.9
98
565
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.3
7.9
32
107
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
11.3
7.9
14
13
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
6.7
7.9
19
30
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
4.2
7.8
21
53
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
6.5
7.7
19
31
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.0
7.7
22
58
D10
ICPC
Vomiting
4.3
7.7
20
49
E55.9
ICD-10 Finland
Vitamin D deficiency, unspecified
19.0
7.7
11
6
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
12.3
7.7
13
11
EBA10
NOMESCO Finland
Operative extraction of tooth
3.0
7.6
36
132
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
25.8
7.6
10
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.5
7.6
51
226
N05CF01
ATC
zopiclone; oral
2.1
7.5
96
558
E11
ICD-10 Finland
Type 2 diabetes mellitus
2.5
7.5
56
260
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.2
7.5
31
105
WX110
NOMESCO Finland
Infiltration anesthesia
2.2
7.5
198
1502
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.6
7.4
25
74
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.5
7.4
50
222
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
9.8
7.4
14
15
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
7.7
7.3
16
22
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.9
7.2
37
142
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.0
7.2
21
56
F10.09
ICD-10 Finland
Alcohol intoxication UNS
8.3
7.2
15
19
J01MA14
ATC
moxifloxacin; systemic
3.0
7.2
34
125
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
12.5
7.1
12
10
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.0
7.1
32
114
F10.24
ICD-10 Finland
Alcohol depence active use
10.4
7.1
13
13
TK800
NOMESCO Finland
Hemodialysis
7.3
7.1
16
23
A01
ICPC
Pain general/multiple sites
3.0
7.1
33
120
N02BE01
ATC
paracetamol; systemic, rectal
3.4
7.1
251
2134
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
4.6
7.1
17
39
ZX070
NOMESCO Finland
Intensity modified radiotherapy
6.1
7.0
18
31
N05AH04
ATC
quetiapine; oral
2.4
7.0
53
247
N05BA04
ATC
oxazepam; oral
2.2
7.0
76
413
C10AA01
ATC
simvastatin; oral
2.0
7.0
116
740
G72.8
ICD-10 Finland
Other specified myopathies
8.6
6.9
14
17
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.4
6.9
54
256
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.1
6.8
19
49
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.9
6.8
33
123
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.3
6.8
26
84
YHMAS, ,
NOMESCO Finland
41.1
6.8
8
*
JFF13
NOMESCO Finland
Terminal enterostomy
41.1
6.8
8
*
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
41.1
6.8
8
*
C07AB02
ATC
metoprolol; systemic
2.3
6.7
58
287
J01DB01
ATC
cefalexin; oral
2.4
6.7
229
1875
R03BB04
ATC
tiotropium bromide; inhalant
2.7
6.7
37
148
JN4KR
NOMESCO Finland
Whole body very extensive metabolic PET with CT
9.0
6.6
13
15
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
9.0
6.6
13
15
ZX120
NOMESCO Finland
Intravenous
2.7
6.6
37
149
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
10.4
6.6
12
12
R55
ICD-10 Finland
Syncope and collapse
2.8
6.5
35
138
C09AA02
ATC
enalapril; systemic
2.2
6.5
62
320
SPAT1247
SPAT
Outpatient detoxication and monitoring
71.5
6.5
7
*
JFF10
NOMESCO Finland
Loop enterostomy
71.5
6.5
7
*
PC5DE
NOMESCO Finland
Ultrasound of kidney circulation with Doppler technic
71.5
6.5
7
*
JJA20
NOMESCO Finland
Open biopsy of liver
71.5
6.5
7
*
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.2
6.4
68
365
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
6.4
59
300
I50.0
ICD-10 Finland
Congestive heart failure
3.3
6.4
25
82
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.1
6.4
27
93
UJF92
NOMESCO Finland
Capsular endoscopy
9.6
6.4
12
13
N18.8
ICD-10 Finland
Other chronic renal failure
9.6
6.4
12
13
A04
ICPC
Weakness/tiredness general
2.5
6.3
41
178
K70.0
ICD-10 Finland
Alcoholic fatty liver
18.5
6.3
9
5
R60.9
ICD-10 Finland
Oedema, unspecified
3.7
6.3
20
57
E87.8
ICD-10 Finland
Other disorders of electrolyte and fluid balance, not elsewhere classified
+∞
6.3
6
*
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
+∞
6.3
6
*
E46
ICD-10 Finland
Unspecified protein-energy malnutrition
+∞
6.3
6
*
F10.49
ICD-10 Finland
Withdrawal symptoms and delirium caused by alcohol without information about seizures
27.4
6.3
8
*
N05CD07
ATC
temazepam; oral
2.7
6.3
36
147
TKC20
NOMESCO Finland
Catheterisation of bladder
3.2
6.3
25
83
WX002
NOMESCO Finland
Sedation and analgesia
2.2
6.3
61
317
N03AX16
ATC
[U] pregabalin
2.1
6.2
66
354
R06.0
ICD-10 Finland
Dyspnoea
2.0
6.2
80
462
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
8.0
6.2
13
17
S06.0
ICD-10 Finland
Concussion
2.7
6.2
35
142
C09BA02
ATC
enalapril and diuretics; systemic
3.0
6.1
27
95
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
7.0
6.1
14
21
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
7.0
6.1
14
21
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.0
6.1
82
481
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.8
6.1
16
29
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.3
6.0
23
74

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
133
296
7.86
63.87
3.6
2.3
2.17
2.32
g/l
1.57
127
276
190
606
8.14
63.12
8.1
4.2
—
—
—
0
0
90
136
9.41
61.13
4.6
3.4
98.88
91.80
ng/l
0.18
81
117
128
288
7.53
60.35
3.5
2.4
20.49
23.95
%
1.45
110
249
136
328
7.32
59.72
3.6
2.3
10.19
13.87
umol/l
6.77
128
309
245
1065
14.55
57.58
23.8
6.5
1.16
1.21
mmol/l
12.09
185
908
232
980
10.50
55.06
18.0
5.7
1.16
1.21
mmol/l
12.62
224
889
98
184
7.78
54.44
3.1
2.1
387.63
353.54
nmol/l
0.66
92
169
164
518
6.49
52.75
3.5
2.0
3.02
3.24
mg/l
0.45
151
456
182
635
6.68
52.22
12.1
4.0
7.41
7.40
ph
0.93
76
134
107
229
7.07
52.13
2.8
2.5
0.19
0.21
g/l
1.68
99
213
197
759
6.84
49.87
6.6
3.8
2.26
2.35
mmol/l
7.98
177
673
47
40
14.01
47.59
2.7
2.9
13.67
15.87
%
1.18
21
19
231
1056
9.05
47.55
16.5
13.7
1.17
1.27
inr
1.77
101
309
45
36
14.79
47.25
3.9
3.4
—
—
—
0
0
238
1182
9.32
42.77
16.1
7.2
10.54
12.08
umol/l
1.71
233
1121
197
845
5.88
41.39
4.1
2.1
68.53
77.78
nmol/l
4.02
185
744
43
40
12.59
41.02
5.0
2.7
2.88
2.01
mmol/l
0.86
35
23
88
193
6.27
40.86
4.4
3.1
64.10
69.55
e9/l
0.68
64
158
81
172
6.29
38.74
9.9
3.5
3.00
2.24
mmol/l
0.60
72
141
100
269
5.31
36.56
10.5
6.9
102.38
104.19
mmol/l
1.99
100
269
97
255
5.37
36.42
4.1
3.0
1.98
1.79
%
0.85
86
241
57
92
7.58
35.45
1.5
2.6
1.53
1.54
g/l
0.02
51
76
69
138
6.37
34.86
5.7
3.3
7.42
7.41
ph
0.18
15
17
142
533
4.50
33.50
2.3
1.5
20.58
20.79
nmol/l
0.04
122
448
233
1292
6.73
32.26
21.0
9.6
4.73
3.93
e9/l
4.26
221
1144
205
1043
4.96
31.19
10.3
6.5
—
—
—
0
0
204
1041
4.88
30.73
8.7
6.2
9.30
8.74
%
1.20
198
977
199
1000
4.73
30.53
8.4
6.0
0.58
0.65
%
1.00
193
935
106
340
4.48
30.39
3.1
2.0
—
—
—
0
0
212
1122
5.09
30.19
8.3
5.8
1.75
1.88
e9/l
0.30
195
1012
209
1096
4.96
30.08
8.1
5.8
0.77
0.58
e9/l
1.57
193
958
209
1100
4.93
29.83
8.1
5.8
0.05
0.04
e9/l
0.53
192
961
205
1064
4.81
29.81
8.6
6.1
21.94
27.23
%
8.49
199
999
122
440
4.22
29.72
4.2
2.6
498.12
563.00
mosm/kgh2o
2.64
111
371
72
172
5.34
29.69
10.8
8.4
—
—
—
0
0
212
1131
5.02
29.62
8.3
5.9
0.18
0.19
e9/l
0.55
195
1005
146
604
4.07
29.14
4.2
2.8
—
—
—
0
0
38
48
9.04
28.87
1.7
1.4
192.56
246.60
ug/g
0.64
25
25
200
1034
4.57
28.86
8.5
5.9
2.36
2.87
%
2.49
194
969
112
394
4.14
27.98
2.3
1.6
1508.43
1278.33
nmol/l
1.20
84
307
84
240
4.62
27.72
10.4
8.0
1.79
1.24
mmol/l
0.44
71
195
180
883
4.09
27.52
4.6
2.5
353.83
144.63
ug/l
2.37
171
813
86
256
4.46
26.83
2.4
1.6
—
—
—
0
0
31
34
10.17
26.12
2.3
3.1
—
—
—
0
0
196
1044
4.17
25.99
8.3
5.9
61.23
57.22
%
3.85
190
981
167
826
3.66
24.17
6.8
3.3
34.19
32.79
ng/l
0.07
151
596
68
182
4.65
24.11
2.5
2.9
64.17
66.24
g/l
0.89
59
168
70
201
4.35
22.57
4.9
4.6
1.27
0.78
%
1.02
42
78
29
36
8.90
22.19
1.7
2.6
—
—
—
0
0
109
437
3.50
21.50
8.3
3.3
2.44
2.45
mmol/l
0.18
99
392
28
35
8.81
21.28
2.5
2.3
—
—
—
0
0
168
886
3.36
20.90
3.1
1.9
84.33
95.91
pmol/l
2.54
122
465
35
59
6.66
20.52
3.5
2.9
1.85
1.46
mg/l
1.17
35
53
54
138
4.64
20.08
9.6
8.9
93.37
94.20
%
0.49
54
138
65
194
4.09
19.70
5.2
3.8
—
—
—
0
0
113
485
3.28
19.65
4.0
2.5
5.40
4.16
e6/l
0.37
102
437
134
637
3.18
19.55
3.8
3.0
2451.64
1132.67
ng/l
3.22
125
538
62
180
4.17
19.50
4.8
4.7
1.08
0.33
%
2.97
36
67
137
661
3.17
19.46
3.8
3.0
0.79
0.40
e6/l
0.81
112
499
69
217
3.92
19.42
1.6
1.4
—
—
—
0
0
145
724
3.16
19.38
5.0
3.1
115.97
135.53
e6/l
0.07
121
561
75
252
3.73
19.16
7.7
5.1
40.65
49.44
ug/l
0.09
67
214
63
189
4.04
18.91
5.1
4.8
0.31
0.09
%
1.24
35
66
181
1037
3.24
18.82
4.1
2.6
—
—
—
0
0
60
179
4.02
18.10
5.0
4.8
0.00
0.04
%
0.80
31
55
131
644
3.00
17.56
4.1
3.1
449.05
240.05
mg/l
0.23
94
407
136
685
2.98
17.40
4.9
3.6
13.92
5.77
mg/mmol
1.58
95
409
76
273
3.48
17.38
1.5
1.3
—
—
—
0
0
45
111
4.66
17.38
14.7
11.3
—
—
—
0
0
134
670
2.98
17.37
4.1
2.9
6.83
8.03
mmol/l
2.38
108
553
130
640
2.98
17.33
3.7
2.9
—
—
—
0
0
54
154
4.13
17.29
1.4
2.6
—
—
—
0
0
102
439
3.12
17.28
2.0
1.7
486.92
439.31
pmol/l
0.60
86
364
71
245
3.57
17.27
3.0
3.0
14.60
9.09
umol/l
0.45
64
216
136
689
2.95
17.16
4.0
2.4
—
—
—
0
0
49
137
4.15
16.06
8.9
4.9
—
—
—
0
0
60
194
3.69
16.01
2.2
2.6
9.93
10.56
g/l
0.50
54
180
150
824
2.84
15.91
6.0
3.6
157.08
92.47
e6/l
0.54
124
599
35
79
4.94
14.97
5.6
3.8
0.19
0.24
g/l
0.31
23
35
41
106
4.38
14.85
7.9
3.3
—
—
—
0
0
221
1544
3.34
14.15
7.6
3.9
—
—
—
0
0
211
1450
3.06
13.63
6.3
3.1
107.85
49.36
u/l
5.56
204
1356
39
104
4.21
13.54
1.8
1.3
—
—
—
0
0
60
217
3.27
13.30
1.7
1.6
—
—
—
0
0
94
439
2.75
13.16
1.4
1.2
1.19
1.19
u/ml
0.00
23
115
106
533
2.62
12.74
4.6
2.3
—
—
—
0
0
164
1015
2.56
12.66
33.0
9.3
0.01
0.00
e9/l
0.31
149
840
72
303
2.87
12.18
1.5
1.2
—
—
—
0
0
23
43
5.75
12.04
3.5
3.2
67.04
56.63
%
2.13
23
43
89
423
2.64
11.86
1.8
1.4
2.73
2.78
g/l
0.09
64
260
22
40
5.90
11.85
3.0
2.6
5.29
4.26
e9/l
0.69
22
40
31
77
4.42
11.75
1.2
3.9
45.48
33.69
mg/l
1.03
24
65
31
77
4.42
11.75
1.2
3.9
51.12
120.60
mg/l
0.41
25
63
169
1084
2.49
11.74
5.3
3.4
0.00
0.00
estimate
-0.00
67
222
169
1089
2.47
11.54
6.9
4.4
0.00
0.00
estimate
-0.00
66
203
112
609
2.43
11.09
5.3
3.8
0.00
0.00
estimate
-0.00
57
199
70
304
2.76
11.07
1.9
1.8
—
—
—
0
0
62
253
2.88
11.01
1.6
1.6
—
—
—
0
0
26
59
4.77
10.99
1.2
1.3
—
—
—
0
0
49
175
3.20
10.98
2.1
2.6
6.92
9.11
ug/l
0.50
38
158
20
19
11.27
10.97
1.5
1.3
—
—
—
0
0
32
87
4.04
10.77
9.6
3.7
—
—
—
0
0
110
602
2.39
10.65
4.8
2.8
4115.84
7534.19
umol/l
0.36
97
523
107
587
2.36
10.22
5.6
3.0
—
—
—
0
0
68
303
2.66
10.15
1.3
1.4
248.89
478.38
titre
1.48
18
74
34
102
3.67
9.96
6.4
2.0
1.58
1.26
%
0.46
34
102
166
1106
2.29
9.87
5.5
3.3
0.00
0.01
estimate
0.50
63
204
33
99
3.66
9.66
6.5
2.0
0.68
0.67
%
0.04
33
99
217
1635
2.64
9.59
5.5
3.6
15.81
14.87
pmol/l
4.57
198
1469
118
701
2.21
9.09
6.4
3.4
—
—
—
0
0
86
449
2.34
9.03
1.7
1.7
1.70
1.35
mg/l
0.68
69
359
13
7
19.42
9.02
1.5
1.1
155.31
144.86
mmol/24h
—
13
7
25
65
4.14
8.91
1.2
4.0
—
—
—
0
0
19
40
5.03
8.73
2.7
2.7
—
—
—
0
0
20
30
7.11
8.54
1.8
2.9
33.05
31.83
pg
0.34
20
30
19
41
4.91
8.49
15.8
8.6
103.84
105.37
mmol/l
0.47
19
35
19
41
4.91
8.49
15.8
8.6
11.63
11.09
mmol/l
0.23
19
35
18
37
5.14
8.49
4.1
2.0
—
—
—
0
0
213
1629
2.44
8.46
6.1
3.8
—
—
—
0
0
60
278
2.49
8.13
2.1
1.5
—
—
—
0
0
7
0
+∞
7.32
1.7
0.0
—
—
—
0
0
261
2268
5.09
7.26
52.8
13.6
29.59
24.14
mg/l
2.08
247
1751
10
5
20.68
7.18
1.5
1.8
—
—
—
0
0
16
23
7.32
7.11
1.4
1.3
475.30
1479.76
e6/l
—
10
17
74
398
2.18
7.03
7.2
3.7
212.48
446.44
ng/l
0.65
64
313
49
228
2.40
6.51
2.8
2.1
193.21
103.84
ug/g
1.83
39
176
44
196
2.49
6.42
4.5
2.7
39.92
31.75
u/l
0.30
38
167
213
1707
2.16
6.36
6.4
4.0
22.36
12.20
mm/h
8.86
194
1558
14
21
6.97
6.12
1.5
1.3
7024.83
37303.00
e6/l
—
6
11
13
18
7.53
6.00
1.4
1.6
—
—
—
0
0
47
228
2.28
5.66
18.5
4.0
—
—
—
0
0
13
20
6.77
5.63
1.6
1.2
—
—
—
0
0
91
574
1.88
5.37
15.7
6.8
—
—
—
0
0
132
935
1.80
5.34
2.4
2.1
—
—
—
0
0
12
18
6.92
5.31
1.2
1.2
—
—
—
0
0
20
64
3.29
5.31
1.0
1.8
—
—
—
0
0
14
26
5.62
5.30
2.2
1.3
17.07
17.21
ug/l
0.01
14
26
5
0
+∞
5.22
1.6
0.0
1.97
—
mmol/l
—
5
0
66
378
1.99
5.16
4.3
2.9
4.56
1.26
e6/l
1.25
36
215
13
23
5.88
5.13
1.6
2.0
—
—
—
0
0
94
609
1.83
5.05
1.8
1.4
—
—
—
0
0
34
150
2.45
5.05
1.8
1.5
—
—
—
0
0
11
16
7.12
5.00
1.5
1.4
—
—
—
0
0
11
17
6.69
4.82
2.3
2.1
38.83
34.01
%
0.49
11
17
34
154
2.38
4.77
1.2
1.2
—
—
—
0
0
15
43
3.63
4.68
1.3
2.0
—
—
—
0
0
154
1884
0.58
4.60
66.0
17.3
330.51
332.95
g/l
2.24
154
1874
16
49
3.41
4.54
2.1
1.3
—
—
—
0
0
236
2051
2.17
4.50
6.8
4.2
2.08
1.94
mu/l
0.48
220
1852
10
16
6.44
4.33
1.1
1.4
—
—
—
0
0
11
21
5.41
4.19
1.3
1.2
—
—
nmol/l
—
0
0
32
151
2.27
4.10
2.1
2.3
4.04
5.74
e9/l
0.50
23
124
8
10
8.20
4.09
1.0
1.0
—
—
—
0
0
17
59
3.01
3.98
2.8
2.5
508.14
124.14
ug/min
—
7
36
13
32
4.21
3.96
1.1
1.1
—
—
—
0
0
14
38
3.83
3.85
2.2
3.4
—
—
—
0
0
11
24
4.73
3.78
1.1
1.0
—
—
—
0
0
14
39
3.73
3.76
1.9
1.8
—
—
—
0
0
15
50
3.12
3.75
1.7
1.4
—
—
—
0
0
13
34
3.96
3.74
1.6
1.4
—
—
—
0
0
8
12
6.83
3.70
1.6
7.4
—
—
—
0
0
8
12
6.83
3.70
1.5
7.8
—
—
—
0
0
7
9
7.95
3.58
1.0
1.0
—
—
—
0
0
11
26
4.36
3.54
3.6
2.5
8.01
3.01
nmol/l
1.36
11
26
12
32
3.87
3.43
3.6
2.8
—
—
—
0
0
38
206
1.98
3.43
3.7
3.2
—
—
—
0
0
10
23
4.47
3.34
1.0
1.0
—
—
—
0
0
222
1945
1.78
3.34
57.0
16.1
16.30
15.13
%
2.21
222
1916
12
33
3.76
3.33
1.1
1.1
—
—
—
0
0
11
28
4.05
3.32
1.6
1.5
—
—
—
0
0
8
16
5.12
3.07
1.9
1.3
—
—
—
0
0
7
12
5.96
3.04
3.9
3.7
87.29
61.58
nmol/l
—
7
12
5
5
10.15
2.99
1.2
1.0
80.00
57.20
nmol/24h
—
5
5
9
23
4.01
2.80
1.0
1.1
—
—
—
0
0
8
19
4.30
2.70
1.1
1.2
—
—
—
0
0
9
24
3.84
2.69
1.3
1.2
—
—
—
0
0
260
2439
2.63
2.68
62.5
16.1
92.78
79.30
umol/l
3.34
260
2439
12
43
2.87
2.68
1.2
1.7
58.33
67.68
%
0.66
12
43
24
122
2.06
2.60
9.5
2.6
0.07
0.16
e6/l
0.93
24
117
255
2383
2.19
2.47
50.6
12.6
—
—
—
0
0
6
12
5.09
2.41
1.0
1.1
129.00
132.17
nmol/l
—
6
12
12
47
2.63
2.30
1.0
1.1
—
—
—
0
0
6
13
4.69
2.28
1.7
1.6
9.83
8.69
mmol/l
—
6
13
23
124
1.93
2.14
1.7
1.6
—
—
—
0
0
30
177
1.78
2.13
1.4
1.5
—
—
—
0
0
14
62
2.33
2.11
1.6
1.2
—
—
—
0
0
8
25
3.26
2.11
2.1
2.4
—
—
—
0
0
8
25
3.26
2.11
1.0
1.2
—
—
—
0
0
48
323
1.59
2.10
1.3
1.3
—
—
—
0
0
11
46
2.45
1.87
1.5
2.1
—
—
—
0
0
11
47
2.40
1.80
1.4
1.6
—
—
—
0
0
12
54
2.28
1.76
5.9
3.8
—
—
—
0
0
6
18
3.38
1.75
1.3
1.3
—
—
—
0
0
5
13
3.90
1.72
1.0
1.1
—
—
—
0
0
262
2524
2.14
1.69
73.4
20.0
36.03
40.44
%
27.94
245
2365
6
19
3.20
1.67
4.2
2.0
—
—
—
0
0
7
25
2.85
1.66
1.1
1.7
—
—
—
0
0
10
42
2.43
1.63
11.1
2.6
1.52
1.71
mmol/l
—
10
42
5
14
3.62
1.62
1.2
1.1
279.40
343.93
nmol/l
—
5
14
9
38
2.41
1.47
12.2
2.7
7.19
7.29
mmol/l
—
9
38
5
16
3.16
1.44
1.4
2.2
2200.40
2365.25
u/ml
—
5
16
10
47
2.17
1.35
1.3
1.6
163.90
290.89
pmol/l
—
10
47
12
61
2.01
1.35
1.2
1.4
—
—
—
0
0
17
99
1.77
1.30
2.0
3.0
—
—
—
0
0
8
34
2.39
1.30
1.3
1.2
—
—
—
0
0
64
502
1.36
1.30
4.3
3.5
—
—
—
0
0
13
72
1.85
1.17
2.1
1.5
—
—
—
0
0
7
30
2.37
1.13
1.4
1.5
—
—
—
0
0
5
21
2.41
1.09
1.0
1.5
—
—
—
0
0
7
32
2.22
1.09
1.0
1.1
—
—
—
0
0
10
175
0.56
1.02
1.1
1.4
—
—
—
0
0
0
30
0.00
0.98
0.0
1.1
—
—
—
0
0
11
62
1.81
0.95
1.2
1.3
—
—
—
0
0
12
73
1.67
0.83
2.1
2.3
21.00
21.66
s
0.17
12
67
14
90
1.59
0.80
1.8
1.6
—
—
—
0
0
6
34
1.78
0.77
1.2
1.2
—
—
—
0
0
5
24
2.10
0.75
4.4
2.4
—
—
—
0
0
117
1053
1.20
0.73
4.5
5.2
1.89
2.60
ug/l
1.00
92
951
5
25
2.02
0.73
1.4
1.1
—
—
—
0
0
5
25
2.02
0.73
4.4
2.4
101.40
105.40
mmol/l
—
5
25
5
25
2.02
0.73
4.4
2.4
3.94
4.06
mmol/l
—
5
25
226
2164
1.27
0.72
8.8
5.3
41.72
39.27
mmol/mol
2.56
208
1999
5
30
1.68
0.61
2.6
1.2
—
—
—
0
0
27
210
1.32
0.61
2.3
2.3
12.27
13.85
nmol/l
0.48
22
194
5
90
0.55
0.56
1.2
1.1
—
—
—
0
0
6
37
1.64
0.56
2.5
1.4
—
—
—
0
0
15
109
1.40
0.52
6.5
2.8
—
—
—
0
0
32
379
0.82
0.43
1.3
1.3
24.63
39.18
iu/ml
—
8
117
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.7
—
—
—
0
0
231
2249
1.18
0.41
6.2
4.5
6.33
5.94
mmol/l
3.76
211
2050
0
18
0.00
0.40
0.0
1.7
—
—
—
0
0
15
116
1.31
0.38
1.1
1.2
148.59
185.78
u/ml
0.21
15
107
6
42
1.44
0.36
2.5
1.3
—
—
—
0
0
6
43
1.40
0.35
2.5
1.3
—
—
—
0
0
6
43
1.40
0.35
2.5
1.3
—
—
—
0
0
6
44
1.37
0.34
2.5
1.3
—
—
—
0
0
31
354
0.86
0.30
1.2
1.3
6.16
15.59
u/ml
—
10
136
11
139
0.78
0.27
1.1
1.2
—
—
—
0
0
227
2313
0.89
0.27
5.4
4.9
2.38
2.76
mmol/l
6.71
202
2114
10
77
1.31
0.26
26.5
10.3
—
—
—
0
0
0
10
0.00
0.21
0.0
7.1
—
0.74
—
0
10
0
10
0.00
0.21
0.0
5.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
20
226
0.88
0.18
1.4
1.5
—
—
—
0
0
5
68
0.73
0.17
3.4
3.4
—
—
—
0
0
24
216
1.12
0.16
1.7
1.6
—
—
—
0
0
6
77
0.77
0.16
1.3
1.2
—
—
—
0
0
51
482
1.07
0.13
6.4
3.7
1.02
1.02
kg/l
—
5
73
83
799
1.06
0.13
3.0
2.7
—
—
—
0
0
17
156
1.10
0.08
2.7
2.5
—
—
—
0
0
7
64
1.10
0.08
1.1
1.2
—
2.53
—
0
10
221
2191
1.05
0.07
4.7
3.9
1.52
1.26
mmol/l
5.16
192
2009
9
102
0.88
0.06
1.2
1.3
—
—
—
0
0
226
2276
0.96
0.06
5.0
4.4
4.30
4.64
mmol/l
4.11
202
2098
225
2264
0.96
0.05
5.0
4.3
1.41
1.46
mmol/l
0.81
199
2079
62
608
1.03
0.03
1.8
1.6
1.39
1.33
mmol/l
0.35
53
499
63
637
0.99
0.01
2.6
3.2
1.38
0.73
ug/l
0.45
40
457
11
111
0.99
0.00
2.5
2.4
—
—
—
0
0
15
145
1.04
0.00
1.1
1.3
—
—
—
0
0
5
58
0.86
0.00
2.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
0.98
—
0
5
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
55
0.91
-0.00
1.0
1.4
—
270.45
miu/ml
—
0
25
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
0.28
—
0
5
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
3.76
—
0
5
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint E4_MG_MET and mortality.

Females

Parameter HR [95% CI] p-value
E4_MG_MET 6.28 [3.89, 10.13] < 0.001
Birth year 0.996 [0.99, 1.0] 0.391

During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 478 females with E4_MG_MET died.

Males

Parameter HR [95% CI] p-value
E4_MG_MET 8.216 [5.17, 13.05] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 237 out of 529 males with E4_MG_MET died.

Mortality risk

Mortality risk for people of age

years, who have E4_MG_MET.

N-year risk Females Males
1 0.659% 1.418%
5 3.779% 8.106%
10 8.898% 19.789%
15 16.579% 34.075%
20 28.077% 50.984%

Relationships between endpoints

↥

Index endpoint: E4_MG_MET – Disorders of magnesium metabolism

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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