Atypical virus infections of central nervous system

AB1_ATYPICAL_CNS_VIRUS

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — A81 Hospital discharge: ICD-8 — 04[5-] Cause of death: ICD-10 — A81 Cause of death: ICD-8 — 04[5-] 2 out of 7 registries used, show all original rules.	344
4. Check minimum number of events None	344
5. Include endpoints None	344
6. Filter based on genotype QC (FinnGen only)	344

Control definitions (FinnGen only)

Control exclude: AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF5

NAME	AB1_ATYPICAL_CNS_VIRUS
CONTROL_EXCLUDE	AB1_VIRAL_CNS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	A81
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	04[5-]
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	A81
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	04[5-]
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Atypical virus infections of central nervous system based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	2894	1340	1530
Only index persons	2514	1171	1343
Unadjusted period prevalence (%)
Whole population	0.04	0.04	0.04
Only index persons	0.05	0.04	0.05
Median age at first event (years)
Whole population	23.36	28.47	18.42
Only index persons	20.77	26.75	15.55

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	344	203	141
Unadjusted period prevalence (%)	0.07	0.07	0.06
Median age at first event (years)	26.33	26.53	26.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
319: Matched controls
3188

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

04599

ICD-8 Finland

Aseptic mentingitis due to enterovirus, Aseptic meningitis, unspecified

+∞

238.6

198

04597

ICD-8 Finland

Aseptic mentingitis due to enterovirus, Suspecta

+∞

49.3

A81.0

ICD-10 Finland

Creutzfeldt-Jakob disease

+∞

25.3

A81.2

ICD-10 Finland

Progressive multifocal leukoencephalopathy

+∞

21.1

04500

ICD-8 Finland

Aseptic mentingitis due to enterovirus, Coxsackie virus

+∞

13.6

32099

ICD-8 Finland

Meningitis, With no organism specified as cause

62.1

10.7

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

2.7

7.3

215

A81.9

ICD-10 Finland

Atypical virus infection of central nervous system, unspecified

+∞

6.3

A81.8

ICD-10 Finland

Other atypical virus infections of central nervous system

+∞

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

181

1230

2.00

8.99

6.2

5.4

1.2

mmol/l

0.52

156

1105

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

103

3.32

8.34

3.9

3.3

25.0

24.9

mmol/l

0.02

(3016018) Differential panel - Cerebral spinal fluid

5.83

7.12

1.6

1.0

—

(3044290) Cell count panel - Cerebral spinal fluid

3.74

6.13

1.5

1.2

—

(3022313) Gas panel - Capillary blood

125

2.72

5.99

3.8

3.1

—

(42870588) Differential panel, method unspecified - Blood

133

905

1.77

5.87

7.7

5.7

—

(3023520) Reticulocytes [#/volume] in Blood

203

2.34

5.84

3.5

2.8

76.0

73.4

e9/l

0.17

160

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

182

1356

1.73

5.80

7.2

6.4

1.2

mmol/l

0.51

136

1143

(3003338) MCHC [Mass/volume]

205

2472

0.58

5.60

23.8

16.5

333.0

332.8

g/l

0.14

205

2462

(3002030) Lymphocytes/100 leukocytes in Blood

181

1362

1.69

5.43

8.1

6.0

28.7

28.3

0.20

170

1281

(3018010) Neutrophils/100 leukocytes in Blood

179

1343

1.69

5.43

7.7

5.8

57.1

56.8

0.10

169

1268

(3032080) INR in Blood by Coagulation assay

152

1092

1.70

5.42

10.7

7.6

1.2

inr

0.01

331

(3027945) Reticulocytes/100 erythrocytes in Blood

282

2.09

5.30

3.1

2.6

1.8

0.03

261

(3032492) JC virus DNA [#/volume] (viral load) in Cerebral spinal fluid by NAA with probe detection

+∞

5.22

1.4

0.0

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

155

2.40

5.09

4.0

3.0

1.3

1.9

mmol/l

0.39

110

(3013826) Glucose [Moles/volume] in Serum or Plasma

205

1621

1.65

4.88

4.0

4.4

6.6

6.7

mmol/l

0.59

194

1521

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

149

1095

1.64

4.69

4.4

3.5

46.9

43.0

ng/l

0.08

105

733

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

604

1.71

4.42

2.2

2.0

3.3

mg/l

0.05

520

(3022096) Basophils/100 leukocytes in Blood

168

1285

1.60

4.42

8.0

5.8

0.7

0.74

160

1204

(3006504) Eosinophils/100 leukocytes in Blood

172

1325

1.60

4.37

7.7

5.8

2.8

2.9

0.22

163

1238

(3019198) Lymphocytes [#/volume] in Blood

183

1437

1.58

4.25

7.1

5.9

2.0

1.9

e9/l

0.28

165

1290

(3019225) pH of Specimen

262

1.97

4.17

7.1

4.2

—

(3044640) Blood type and Crossmatch panel - Blood

119

850

1.61

4.09

3.2

2.2

—

(3031040) Bacteria [#/volume] in Urine by Automated count

216

1772

1.59

4.08

4.7

4.1

9.0

2244.0

e6/l

—

(3019069) Monocytes/100 leukocytes in Blood

171

1331

1.57

4.06

8.5

6.1

8.4

8.6

0.32

163

1256

(3012095) Magnesium [Moles/volume] in Serum or Plasma

436

1.76

4.02

3.2

3.3

0.8

mmol/l

0.35

408

(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection

10.17

4.02

1.3

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

647

1.65

3.93

2.8

2.2

—

(3013115) Eosinophils [#/volume] in Blood

183

1458

1.55

3.84

7.6

6.1

0.2

e9/l

0.02

160

1307

(3001604) Monocytes [#/volume] in Blood

177

1406

1.53

3.73

7.4

5.9

0.6

e9/l

0.22

157

1239

(3006315) Basophils [#/volume] in Blood

177

1411

1.52

3.64

7.4

5.9

0.0

e9/l

2.14

157

1247

(3023368) Bacteria identified in Blood by Culture

690

1.59

3.50

5.3

4.0

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

396

1.72

3.49

1.6

1.8

29.5

29.6

0.07

385

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

406

1.71

3.43

2.1

1.9

—

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

358

1.75

3.43

2.8

2.1

22.3

22.5

0.03

308

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

3.78

3.38

5.3

1.9

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

223

1.90

3.28

4.2

3.5

1.2

mmol/l

0.35

198

(3000093) Morphology [Interpretation] in Blood Narrative

4.83

3.26

1.0

1.3

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.55

3.18

1.3

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

367

1.70

3.14

5.1

4.4

29.3

31.8

1.23

241

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

3.31

3.08

1.1

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

7.61

3.06

1.2

1.1

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

7.61

3.06

1.2

1.1

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

7.61

3.06

1.2

1.1

—

(3014271) Vancomycin [Susceptibility]

5.93

3.03

2.9

2.3

—

(3000850) Epithelial cells [#/volume] in Urine

554

1.58

3.03

2.5

2.4

4.3

7.0

e6/l

0.95

488

(3015377) Calcium [Moles/volume] in Serum or Plasma

124

948

1.48

2.97

3.8

3.2

2.3

2.4

mmol/l

1.76

102

836

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

4.79

2.93

1.3

1.0

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

613

1.54

2.86

1.5

1.8

1.2

1.1

mg/l

0.08

472

(3013650) Neutrophils [#/volume] in Blood by Automated count

197

1654

1.45

2.85

12.4

9.5

4.0

e9/l

0.13

173

1465

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

3.12

2.83

1.1

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

132

2.05

2.78

5.0

9.2

23.9

24.9

mmol/l

0.51

123

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

2.31

2.76

1.8

2.6

—

(3021960) Folate [Moles/volume] in Serum or Plasma

618

1.52

2.75

1.7

1.5

22.7

21.6

nmol/l

0.26

520

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

6.08

2.71

1.8

1.1

—

(3013512) EKG study

109

827

1.47

2.67

4.3

3.8

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

7.23

2.55

1.2

1.1

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

7.23

2.55

1.2

1.1

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

5.53

2.55

1.0

1.1

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

5.53

2.55

1.2

1.1

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.38

2.52

2.0

1.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

2.35

2.45

1.1

—

(3026782) Osmolality of Urine

529

1.51

2.41

2.5

2.4

559.9

562.0

mosm/kgh2o

0.02

456

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

5.07

2.41

1.2

—

(3003396) Base excess in Arterial blood by calculation

294

1.65

2.41

4.5

7.7

0.9

1.4

mmol/l

0.25

239

(3018418) pH of Serum or Plasma

108

835

1.43

2.35

4.0

3.6

7.4

0.29

157

(3026493) Urate [Moles/volume] in Serum or Plasma

755

1.44

2.32

2.7

2.5

3747.1

7104.6

umol/l

0.41

644

(40760888) Immunoglobulin light chains.free panel - Serum

2.43

2.32

1.9

5.2

—

(3023410) Appearance of Cerebral spinal fluid

3.27

2.32

2.0

1.1

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

3.54

2.28

1.6

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

133

1073

1.39

2.26

2.2

1.9

109.8

97.1

pmol/l

1.60

538

(3034860) Kappa light chains.free [Mass/volume] in Serum

2.18

2.22

1.6

4.5

35.4

39.9

mg/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

2.18

2.22

1.6

4.5

135.4

25.9

mg/l

—

(3019309) Folate [Moles/volume] in Red Blood Cells

462

1.50

2.17

2.1

1.7

1120.7

1233.6

nmol/l

0.47

349

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

3.05

2.16

1.2

1.1

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

2.42

2.15

1.2

1.3

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

111

875

1.40

2.14

2.4

2.5

62.2

56.7

u/l

0.38

810

(3024561) Albumin [Mass/volume] in Serum or Plasma

145

1195

1.37

2.14

5.3

4.4

34.8

36.1

g/l

1.55

133

1124

(3011288) Drugs identified in Urine by Screen method

2.45

2.05

1.2

2.3

—

(21494755) Public health laboratory ask at order entry panel

320

0.51

2.04

1.7

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

153

1280

1.35

2.02

4.8

3.8

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

259

1.62

2.01

2.9

1.9

349.5

373.6

nmol/l

0.36

244

(3028707) Methadone [Presence] in Urine by Screen method

2.61

1.93

1.2

1.9

—

(3017732) Neutrophils [#/volume] in Blood

191

1.68

1.88

4.0

2.5

4.0

3.8

e9/l

0.14

156

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

223

1.63

1.88

2.4

2.3

5.8

7.9

ug/l

0.47

200

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

153

1.76

1.85

2.0

1.3

—

(3021589) Normoblasts [#/volume] in Blood

149

1254

1.33

1.85

11.1

9.4

0.0

e9/l

0.58

122

1040

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

3.57

1.84

1.0

1.1

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

246

2228

1.37

1.84

8.7

7.5

79.2

77.5

u/l

0.20

228

2080

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

4.21

1.83

1.0

1.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

178

1.69

1.79

2.9

2.4

—

(3022217) INR in Platelet poor plasma by Coagulation assay

317

1.52

1.79

31.1

17.0

—

1.2

—

(3037121) Protein [Mass/volume] in Urine

103

1.89

1.75

5.3

3.6

0.5

0.2

g/l

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

2.96

1.73

1.9

1.3

—

(3021788) Differential panel - Synovial fluid

2.33

1.72

1.3

1.6

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

295

1.52

1.71

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

476

1.42

1.70

1.8

1.4

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

1.97

1.67

2.3

2.2

1955.8

377.6

ug/l

0.62

(4027681)

3.19

1.67

1.3

1.2

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

3.19

1.67

1.0

1.2

—

(3013707) Erythrocyte sedimentation rate by Westergren method

236

2145

1.32

1.59

4.7

4.1

13.2

11.4

mm/h

0.81

213

1977

(3007853) Bacteria identified in Skin by Aerobe culture

309

1.49

1.58

1.8

1.6

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

2.07

1.56

2.0

1.9

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

276

1.51

1.56

3.8

3.2

—

(3000330) Specific gravity of Urine by Test strip

142

0.41

1.56

2.3

3.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

285

1.50

1.54

1.5

1.8

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.87

1.54

2.6

1.9

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

172

1504

1.29

1.53

7.2

6.3

10.2

10.8

umol/l

0.50

160

1425

(3008898) HLA-B27 [Presence]

126

0.39

1.53

1.2

1.1

—

(3016244) Insulin [Units/volume] in Serum or Plasma

3.37

1.53

2.6

3.5

17.6

16.4

mu/l

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

3.37

1.53

1.0

1.1

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

1.52

0.0

2.5

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.94

1.52

2.0

2.6

1.2

1.5

mg/l

1.17

(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma

195

1.59

1.52

3.8

3.3

94.4

73.6

ng/l

0.47

172

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

140

1.69

1.49

2.4

—

(40761536) Microorganisms panel - Urine sediment

229

1.54

1.48

3.8

3.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

288

1.48

1.47

1.6

1.8

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

149

1.66

1.45

1.8

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

3.15

1.44

1.6

1.4

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

2.11

1.40

1.1

1.5

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

2.44

1.40

1.1

1.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

2.44

1.40

1.1

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

2.44

1.40

4.9

3.0

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

2.44

1.40

2.1

2.0

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

2.64

1.37

1.0

1.3

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

2.97

1.36

1.6

1.5

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

2.97

1.36

1.6

1.4

—

(3012501) Base excess in Blood by calculation

2.07

1.34

3.4

2.7

1.7

3.4

mmol/l

—

(3037756) Immunofixation for Serum or Plasma

2.07

1.34

1.7

1.6

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

355

1.41

1.33

12.1

6.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

194

1.54

1.32

2.5

1.4

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

254

1.47

1.28

5.0

8.1

124.0

123.1

g/l

0.09

244

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

2.07

1.27

2.2

1.4

—

(3019060) Gas panel - Arterial blood

171

1.56

1.27

3.2

5.1

—

(3009466) Valproate [Moles/volume] in Serum or Plasma

2.25

1.25

2.9

3.7

327.3

376.0

umol/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

115

977

1.27

1.24

3.9

2.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

2.03

1.24

1.1

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

2.00

1.23

2.8

6.8

—

193.3

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

2.65

1.22

1.2

1.3

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

568

1.32

1.21

1.6

1.7

502.7

444.7

pmol/l

0.57

480

(3029937) Albumin [Presence] in Urine by Test strip

744

1.28

1.21

3.8

3.7

0.0

estimate

0.69

252

(40761511) CBC panel - Blood by Automated count

313

3006

1.46

1.20

18.3

12.0

—

(4306422)

2.13

1.19

1.3

1.2

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

2.33

1.19

2.0

2.5

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

300

2862

1.38

1.18

18.7

12.8

23.8

21.8

mg/l

0.40

251

2235

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

1.16

0.0

1.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

291

2765

1.34

1.16

16.5

12.0

80.8

82.2

ml/min/173m2

0.50

244

2261

(40768797) Stomach Pathology biopsy report

409

1.35

1.16

1.3

1.2

—

(40768441) Liver Pathology biopsy report

2.52

1.15

1.2

1.4

—

(3002582) Erythrocytes [#/volume] in Urine

833

1.26

1.15

3.3

2.9

412.5

119.3

e6/l

0.34

634

(3026008) Bacteria identified in Urine by Culture

806

1.27

1.14

2.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

144

1.56

1.11

2.4

1.5

—

(3044941) Cell count panel - Synovial fluid

1.97

1.09

1.1

1.4

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

2.40

1.09

15.8

11.4

751.4

972.0

nmol/l

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

2.40

1.09

26.2

16.9

1251.6

1628.9

nmol/l

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

240

0.61

1.08

1.8

2.7

61.5

65.3

ml/min/173m2

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.66

1.05

3.1

2.1

—

(36304419) Bacteria [Presence] in Urine

739

1.26

1.04

3.4

2.7

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

1.94

1.03

8.4

3.1

4.5

4.8

e9/l

—

(3021440) Promyelocytes/100 leukocytes in Blood

232

1.42

1.02

5.1

4.8

0.0

0.1

2.18

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

1.90

1.01

8.7

3.6

57.6

58.4

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

234

2180

1.23

1.01

4.4

3.9

14.8

14.7

pmol/l

0.34

209

1978

(3017181) Myelocytes/100 leukocytes in Blood

250

1.40

1.00

5.1

4.6

0.8

0.04

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

2.02

1.00

1.9

1.3

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

761

1.25

1.00

3.5

3.1

753.8

965.9

ng/l

0.53

638

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

2.19

0.98

1.0

1.7

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.98

0.0

1.2

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.98

0.0

1.2

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.98

0.0

1.2

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.97

0.0

1.2

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.97

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.97

0.0

1.2

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

141

1.52

0.97

5.9

8.6

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

1.82

0.97

1.1

1.3

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

1.82

0.97

1.1

1.3

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

133

1176

1.21

0.96

2.6

2.2

78.4

76.4

nmol/l

0.32

115

1051

(3018095) Leukocytes [#/volume] in Urine

113

983

1.22

0.96

3.7

3.4

64.4

89.7

e6/l

0.27

692

(3038177) Helicobacter pylori Ab [Presence] in Serum

1.91

0.94

1.0

1.2

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

2.24

0.94

2.2

2.1

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

1.74

0.93

1.4

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

1.75

0.93

1.0

1.1

—

(4035726)

254

1.38

0.93

1.5

1.4

—

(21494890) Protein electrophoresis panel - 24 hour Urine

2.16

0.92

1.5

2.8

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.93

0.89

1.0

1.1

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.81

0.88

1.2

1.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

207

1920

1.20

0.87

4.5

4.1

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

2.02

0.87

1.0

1.1

—

(40768443) Skin Pathology biopsy report

112

1.54

0.86

1.1

1.3

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

1.84

0.86

1.5

3.0

—

1275.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

194

1792

1.19

0.85

3.2

2.9

—

(3025130) Human papilloma virus identified in Specimen

1.95

0.85

1.7

1.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

250

1.35

0.84

1.3

1.4

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.72

0.83

1.3

1.6

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.76

0.83

1.1

1.4

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

1.76

0.83

1.0

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

1.60

0.82

1.6

1.5

—

0.1

—

(3020961) Endomysium IgA Ab [Titer] in Serum

147

1.46

0.82

1.1

—

132.2

—

(3023419) Bacteria identified in Sputum by Culture

1.89

0.82

2.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

1.89

0.82

1.2

1.3

—

(3022806) Fractional oxyhemoglobin in Capillary blood

1.89

0.82

1.7

1.8

92.3

90.8

—

(3002256) Pathology report gross observation

332

1.30

0.81

1.2

—

(40768795) Lymph node Pathology biopsy report

1.83

0.79

1.0

—

(40768804) Tissue Pathology biopsy report

128

1146

1.19

0.79

2.1

2.0

—

(3008295) Osmolality of Serum or Plasma

0.00

0.78

0.0

1.5

—

280.6

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.56

0.76

1.4

1.6

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

1.72

0.76

2.2

1.6

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

1.72

0.76

1.7

2.3

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

1.62

0.76

1.2

1.3

—

(1616796) Gas panel - Central venous blood

1.68

0.75

3.8

2.3

—

(3032773) Endomysium IgG Ab [Titer] in Serum

2.10

0.75

1.0

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

2.10

0.75

1.2

3.1

—

(3002179) Metamyelocytes/100 leukocytes in Blood

229

1.34

0.74

4.6

0.3

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.65

0.74

1.4

1.5

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

1.59

0.71

1.9

1.5

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

1.72

0.70

1.4

1.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

196

1.35

0.70

1.3

1.6

—

(3019150) Specific gravity of Urine by Refractometry

609

1.21

0.70

3.8

3.7

1.0

kg/l

0.03

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.61

0.69

2.5

1.6

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

1.86

0.68

1.2

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.53

0.67

1.6

1.3

—

2.3

—

(3009542) Hematocrit [Volume Fraction] of Blood

276

2653

1.20

0.67

17.8

13.6

39.3

40.7

1.52

178

1966

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

1.64

0.67

1.4

1.5

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

1.80

0.66

1.2

1.3

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

307

2984

1.27

0.66

20.9

14.5

139.4

139.7

mmol/l

1.71

298

2915

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

103

1.48

0.66

1.1

1.8

—

(3009508) Creatinine [Moles/volume] in Urine

880

1.18

0.66

3.2

3.1

8.0

7.6

mmol/l

0.29

743

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

1.68

0.61

1.4

1.5

—

(3000764) Benzodiazepines [Presence] in Urine

1.50

0.61

1.2

1.7

—

(3015183) Erythrocyte sedimentation rate

0.00

0.60

0.0

1.4

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

628

1.19

0.60

1.4

1.3

0.5

1.2

u/ml

2.23

175

(3027008) Opiates [Presence] in Urine

1.48

0.59

1.2

1.7

—

(3028300) Cannabinoids [Presence] in Urine

1.48

0.59

1.2

1.7

—

(3001467) Alkaline phosphatase.bone [Enzymatic activity/volume] in Serum or Plasma

0.00

0.58

0.0

1.2

—

52.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

294

2853

1.21

0.58

5.1

4.4

6.0

5.9

mmol/l

0.08

254

2628

(3045142) Bone marrow Pathology biopsy report

1.73

0.58

1.2

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

1.50

0.58

1.1

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

1.49

0.57

1.4

1.1

—

(3002523) Influenza virus A Ag [Presence] in Specimen

1.49

0.57

1.4

1.1

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

442

1.21

0.57

1.5

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

121

1105

1.15

0.56

3.7

3.5

—

(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum

0.55

0.56

2.0

1.3

—

3.3

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.46

0.56

1.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

680

1.17

0.56

5.9

4.9

—

(3018572) Chloride [Moles/volume] in Blood

1.51

0.54

3.3

6.6

105.9

105.8

mmol/l

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

1.51

0.54

1.3

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

1.51

0.54

1.1

1.3

—

(3039000) Anion gap in Blood

1.51

0.54

3.3

6.6

9.9

10.8

mmol/l

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

210

1992

1.14

0.54

3.6

3.2

53.1

47.3

u/l

0.44

197

1875

(3047007) Chlamydophila sp Ab [Presence] in Serum

1.59

0.54

1.2

1.1

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

656

0.84

0.54

3.4

3.8

23.7

21.0

0.54

266

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

273

2638

1.17

0.54

5.4

4.6

2.0

2.3

mu/l

0.33

240

2410

(3000494) Fungus identified in Specimen by Culture

343

1.22

0.53

1.4

—

(3025941) Bacteria identified in Stool by Culture

161

1.32

0.53

1.4

1.2

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

307

2997

1.23

0.53

20.9

14.5

4.0

mmol/l

0.39

298

2922

(3025159) Blasts/100 leukocytes in Blood

224

1.27

0.53

5.4

4.8

0.0

0.2

0.57

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

503

1.18

0.52

3.6

2.6

2.5

2.4

mmol/l

0.27

448

(3041096) Erythrocytes [Presence] in Urine by Automated

800

1.15

0.51

3.1

3.0

—

(3030467) Casts [#/volume] in Urine by Automated count

752

1.15

0.51

3.4

2.7

0.3

0.5

e6/l

0.95

552

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

198

1.28

0.51

1.2

1.4

—

34.8

—

(3022621) pH of Urine by Test strip

189

0.73

0.49

4.2

2.6

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

1.57

0.49

1.1

1.3

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

1.53

0.48

1.0

1.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

1.50

0.48

1.4

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

320

1.21

0.47

1.4

1.5

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

1.47

0.47

1.1

—

(3048689) Calprotectin [Mass/mass] in Stool

340

1.20

0.45

1.9

2.2

854.0

118.3

ug/g

0.58

272

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

1.41

0.45

1.1

—

(3000991) Gas panel - Venous blood

202

1.26

0.45

7.4

7.9

—

(3037522) Nuclear Ab [Titer] in Serum

407

1.18

0.44

1.2

1.4

937.1

548.0

titre

—

(3042631) Mycobacterium sp identified in Specimen

1.62

0.43

3.4

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.37

0.42

2.2

1.6

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

1.44

0.42

2.1

1.6

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

1.4

—

22.3

—

(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline

0.00

0.41

0.0

1.1

—

7.4

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.41

0.0

1.5

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

168

1.27

0.41

5.4

8.1

26.4

24.8

mmol/l

1.52

156

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.41

0.0

1.1

—

(3020013) Alkaline phosphatase.intestinal [Enzymatic activity/volume] in Serum or Plasma

0.00

0.41

0.0

1.3

—

13.1

—

(3000012) Reticulocyte production index

0.00

0.41

0.0

1.5

—

(3020891) Body temperature

1.35

0.40

3.5

5.3

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

1.43

0.39

1.0

1.3

—

(3026470) Cobalt [Mass/volume] in Blood

0.00

0.39

0.0

2.5

—

4.2

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.39

0.39

3.5

2.1

—

(3027944) Amphetamines [Presence] in Urine

1.36

0.38

1.3

1.7

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

1.39

0.38

1.4

—

(3000492) Spirometry study

282

1.19

0.37

1.2

1.5

—

(3047181) Lactate [Moles/volume] in Blood

1.37

0.36

3.5

6.4

1.3

1.2

mmol/l

0.42

(3045424) Erythrocytes [Presence] in Urine

1.34

0.34

1.3

1.6

—

(3044889) 12 lead EKG panel

214

2066

1.09

0.33

4.1

3.7

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

126

1188

1.10

0.33

3.1

2.5

148.1

116.3

ug/l

1.07

114

1096

(3016879) Cocaine [Presence] in Urine

1.34

0.32

1.3

1.7

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.32

0.32

1.3

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.32

0.32

1.3

1.2

—

(4034850)

0.71

0.31

9.9

6.9

—

(3035350) Ketones [Presence] in Urine by Test strip

147

1400

1.09

0.30

3.5

3.4

0.0

estimate

0.00

260

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

102

1.29

0.30

3.2

2.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

567

1.11

0.29

1.5

2.4

2.5

g/l

0.08

348

(3003694) ABO and Rh group [Type] in Blood

742

1.10

0.29

1.4

1.3

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

1.22

0.27

1.4

1.2

—

(3052851) Hemolysis interference index of Serum or Plasma

1.31

0.26

3.2

3.0

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.70

0.26

1.4

1.2

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.68

0.26

2.4

2.0

235.2

246.5

pmol/l

—

(3012516) Albumin [Mass/volume] in Urine

836

1.09

0.25

3.5

3.2

1017.7

286.4

mg/l

0.34

529

(46235355) HIV 1 and 2 tests - Meaningful Use set

389

1.12

0.25

2.2

1.7

—

(3042936) Bacteria identified in Isolate by Culture

399

1.12

0.24

2.3

1.8

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

201

0.84

0.24

1.5

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

287

2823

1.10

0.24

4.4

4.0

1.4

1.3

mmol/l

0.63

253

2606

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

482

0.90

0.23

2.8

0.6

0.7

ug/l

0.86

277

(4268621)

1.32

0.23

1.8

2.1

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

1.32

0.23

1.0

1.3

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

1.22

0.22

1.0

1.3

0.5

nmol/l

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.21

0.0

1.2

—

(1175556) inFLIXimab Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

3.7

—

38.6

—

(3032567) Hepatitis B virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.21

0.0

2.2

—

(44806420)

0.00

0.21

0.0

2.5

—

(3035544) Cardiolipin IgG Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.1

—

(40757494) Bilirubin.total [Moles/volume] in Blood

0.00

0.21

0.0

1.5

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

4.3

—

5.6

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

0.21

0.0

1.2

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

221

1.14

0.20

2.1

2.6

—

7.7

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

112

0.80

0.20

1.1

1.0

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.20

0.0

1.2

—

194.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.20

0.0

1.0

—

(3020682) Albumin/Creatinine [Ratio] in Urine

884

1.07

0.20

4.7

4.0

7.2

8.1

mg/mmol

0.10

550

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

290

1.11

0.19

5.3

4.4

15.6

20.8

ug/l

0.11

245

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

465

0.91

0.18

3.3

2.4

1.5

1.1

e6/l

0.25

253

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

237

0.88

0.18

2.6

1.9

—

(3000963) Hemoglobin [Mass/volume] in Blood

320

3226

0.88

0.18

28.5

19.1

133.7

136.8

g/l

3.22

315

3178

(3039443) Prostate specific Ag panel - Serum or Plasma

1.17

0.18

1.6

1.5

—

(3001019) Free T4 and TSH panel - Serum or Plasma

163

0.85

0.17

1.4

1.7

—

(3026361) Erythrocytes [#/volume] in Blood

320

3225

0.89

0.17

28.4

19.0

4.4

4.5

e12/l

3.23

314

3132

(3010813) Leukocytes [#/volume] in Blood

320

3225

0.89

0.17

28.4

19.1

6.7

6.5

e9/l

0.93

315

3131

(40758558) Short blood count panel - Blood

722

1.07

0.17

8.1

6.8

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

101

1.19

0.17

1.3

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

438

1.08

0.17

3.2

2.6

1.6

2.2

e6/l

0.53

229

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

808

0.94

0.16

1.8

1.7

1.3

1.4

mmol/l

0.70

689

(3035941) MCH [Entitic mass]

320

3224

0.89

0.16

28.3

18.9

30.5

30.3

0.75

315

3180

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.10

0.16

1.4

1.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

284

1.10

0.15

1.5

1.6

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

275

0.90

0.15

2.1

2.3

35.5

31.5

u/l

0.11

239

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

212

0.89

0.14

2.5

1.7

—

(3012544) pH of Venous blood

243

0.90

0.14

4.0

3.4

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.80

0.14

1.4

2.2

10.0

10.1

g/l

—

(3009261) Glucose [Presence] in Urine by Test strip

146

1422

1.05

0.13

3.7

3.4

0.0

estimate

0.50

249

(40761535) Cells panel - Urine sediment

219

1.10

0.13

4.2

3.4

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

295

2923

1.06

0.12

5.0

4.5

4.8

mmol/l

0.14

265

2727

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

279

1.08

0.11

1.7

1.8

—

(3002385) Erythrocyte distribution width [Ratio]

243

2399

1.04

0.11

19.9

15.9

13.6

13.7

0.45

235

2358

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

296

2980

0.95

0.08

5.2

5.0

2.8

mmol/l

0.29

264

2756

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

276

2739

1.04

0.07

5.9

5.6

39.2

39.7

mmol/mol

0.46

247

2562

(3021447) Carbon dioxide [Partial pressure] in Venous blood

235

0.93

0.07

3.8

3.3

5.6

5.8

kpa

0.36

229

(4094501)

1.05

0.07

1.0

1.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

147

1.09

0.07

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

143

1407

1.03

0.07

4.7

0.0

estimate

0.50

263

(3045414) Leukocytes [Presence] in Urine

122

0.90

0.07

1.5

1.9

—

(3049717) Cytology report of Urine Cyto stain

0.84

0.06

2.0

2.8

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

293

2913

1.04

0.06

4.9

4.5

1.5

mmol/l

0.58

260

2698

(3013139) Helicobacter pylori Ag [Presence] in Stool

188

1.07

0.05

1.3

—

(36660697) Celiac disease serology panel - Serum

218

1.06

0.05

1.5

1.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

140

0.93

0.04

1.0

—

(3022145) Colonoscopy Study observation

332

0.96

0.04

1.3

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

111

1.08

0.04

3.1

5.4

1.0

0.9

0.26

103

(4010399)

220

1.05

0.03

1.7

1.4

—

(3023081) Carboxyhemoglobin/Hemoglobin.total in Blood

112

1.07

0.03

2.8

5.3

2.0

1.6

0.60

103

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

499

0.98

0.02

1.3

15.9

12.5

u/ml

0.14

205

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

107

0.93

0.02

1.3

2.2

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

819

0.99

0.01

3.7

4.2

1.7

2.3

ug/l

0.69

731

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

526

0.99

0.00

1.4

1.3

69.8

39.5

iu/ml

0.37

170

(3011397) Hemoglobin [Presence] in Urine by Test strip

636

0.99

0.00

3.5

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

501

1.00

0.00

3.5

3.6

267.6

249.3

ng/l

0.04

384

(1761868) Lipid panel - Serum or Plasma

113

1129

1.00

0.00

3.0

2.9

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

105

0.95

0.00

1.4

—

(1002224) Polysomnography panel

144

0.97

0.00

1.1

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

312

3116

1.01

0.00

12.8

10.3

27.1

27.2

u/l

0.04

293

3017

(3020564) Creatinine [Moles/volume] in Serum or Plasma

311

3106

1.01

0.00

20.3

15.1

78.1

75.2

umol/l

0.89

311

3106

(3013293) Extractable nuclear Ab [Presence] in Serum

0.00

0.0

1.7

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.00

0.00

1.1

1.3

—

(3012741) Chlamydophila pneumoniae IgA Ab [Titer] in Serum

0.00

0.0

1.0

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

0.0

2.0

—

1.2

—

(40768793) Breast Pathology biopsy report

0.91

0.00

1.6

1.3

—

(3024928) Oxygen saturation in Venous blood

0.94

0.00

5.6

2.4

—

(3018993) Complement total hemolytic CH100 [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3022689) Creatine [Moles/volume] in Urine

0.00

0.0

1.6

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.93

0.00

1.4

2.2

32.8

38.7

g/l

—

(3009876) Amylase isoenzyme 3 panel - Serum or Plasma

0.00

0.0

1.2

—

(3044007) Cell count panel - Peritoneal fluid

0.00

0.0

1.2

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

0.0

1.0

—

(3001501) Glucose [Moles/volume] in Capillary blood by Glucometer

0.00

0.0

1.0

—

6.2

—

(37021073) Hepatitis C virus genotype in Serum or Plasma by Sequencing

0.00

0.0

1.2

—

(3002619) Bacteria identified in Specimen by Culture

0.00

0.0

1.2

—

(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.2

—

(3020073) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Specimen

0.00

0.0

1.7

—

(3006441) Cardiolipin IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

0.0

1.3

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.96

0.00

1.1

—

10.8

—

(4133840)

0.00

0.0

1.0

—

(40760007) HIV 1+2 Ab+HIV1 p24 Ag [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

(3014300) Beta 2 glycoprotein 1 IgM Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(42869593) Oxyhemoglobin/Hemoglobin.total [Pure mass fraction] in Capillary blood

0.00

0.0

4.4

—

(44817194) Complement alternate pathway AH50 actual/normal in Serum by Immunoassay

0.00

0.0

1.0

—

100.3

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.98

0.00

1.0

1.5

—

(40768446) Kidney Pathology biopsy report

0.00

0.0

1.4

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

0.91

0.00

1.8

1.9

—

(3035509) Tobramycin [Mass/volume] in Serum or Plasma

0.00

0.0

3.4

—

1.0

—

(40758292) HTLV I+II Ab panel - Serum

0.00

0.0

1.6

—

(3041870) Hepatitis C virus IgG Ab [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.2

—

(3051101) Glucose [Moles/volume] in Cord blood

0.00

0.0

3.6

—

(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood

0.00

0.0

2.2

—

1.3

—

(3000213) Normetanephrine [Moles/time] in 24 hour Urine

0.00

0.0

1.2

—

1.8

—

(3013803) Aspergillus fumigatus IgG Ab [Mass/volume] in Serum

0.00

0.0

1.0

—

(40757373) Influenza virus identified in Isolate

0.00

0.0

1.4

—

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_ATYPICAL_CNS_VIRUS and mortality.

Females

Parameter	HR [95% CI]	p-value
AB1_ATYPICAL_CNS_VIRUS	4.8 [2.84, 8.11]	< 0.001
Birth year	0.991 [0.98, 1.0]	0.049

During the follow-up period (1.1.1998 — 31.12.2019), 147 out of 229 females with AB1_ATYPICAL_CNS_VIRUS died.

Males

Parameter	HR [95% CI]	p-value
AB1_ATYPICAL_CNS_VIRUS	8.359 [4.15, 16.85]	< 0.001
Birth year	0.988 [0.98, 1.0]	0.011

During the follow-up period (1.1.1998 — 31.12.2019), 127 out of 186 males with AB1_ATYPICAL_CNS_VIRUS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ATYPICAL_CNS_VIRUS.

N-year risk	Females	Males
1	0.359%	1.382%
5	2.327%	8.753%
10	5.99%	22.142%
15	11.43%	38.663%
20	19.64%	57.268%

Relationships between endpoints

↥

Index endpoint: AB1_ATYPICAL_CNS_VIRUS – Atypical virus infections of central nervous system

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Atypical virus infections of central nervous system

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints