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Atypical virus infections of central nervous system

EFO Endpoint Browser PheWeb

AB1_ATYPICAL_CNS_VIRUS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — A81
  • Hospital discharge: ICD-8 — 04[5-]
  • Cause of death: ICD-10 — A81
  • Cause of death: ICD-8 — 04[5-]

2 out of 7 registries used, show all original rules.

348

4. Check minimum number of events

None

348

5. Include endpoints

None

348

6. Filter based on genotype QC (FinnGen only)

337

Control definitions (FinnGen only)

Control exclude
AB1_VIRAL_CNS

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2894 1340 1530
Only index persons 2514 1171 1343
Unadjusted period prevalence (%)
Whole population 0.04 0.04 0.04
Only index persons 0.05 0.04 0.05
Median age at first event (years)
Whole population 23.36 28.47 18.42
Only index persons 20.77 26.75 15.55

-FinnGen-

Key figures

All Female Male
Number of individuals 337 199 138
Unadjusted period prevalence (%) 0.07 0.07 0.06
Median age at first event (years) 26.13 26.15 26.09

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
348
Matched controls
3480
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
04599
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Aseptic meningitis, unspecified
+∞
248.9
208
*
04597
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Suspecta
+∞
53.5
50
*
A81.0
ICD-10 Finland
Creutzfeldt-Jakob disease
+∞
30.7
29
*
A81.2
ICD-10 Finland
Progressive multifocal leukoencephalopathy
+∞
25.3
24
*
04500
ICD-8 Finland
Aseptic mentingitis due to enterovirus, Coxsackie virus
+∞
15.7
15
*
32099
ICD-8 Finland
Meningitis, With no organism specified as cause
33.6
10.4
13
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
8.1
88
475
A81.8
ICD-10 Finland
Other atypical virus infections of central nervous system
+∞
7.3
7
*
A81.9
ICD-10 Finland
Atypical virus infection of central nervous system, unspecified
+∞
7.3
7
*
N03AX12
ATC
[U] gabapentin; oral
2.1
7.0
72
378
J01MA12
ATC
levofloxacin; systemic
2.1
7.0
72
378
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.7
6.7
21
59
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
6.7
61
306
N03AG01
ATC
valproic acid; systemic, rectal
2.9
6.0
28
101

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
184
1254
1.99
9.05
6.2
5.4
1.21
1.22
mmol/l
0.55
160
1132
32
104
3.29
8.21
3.9
3.3
24.98
24.96
mmol/l
0.01
26
98
46
207
2.41
6.45
3.4
2.8
75.75
73.13
e9/l
0.17
34
163
19
53
3.73
6.12
1.5
1.2
—
—
—
0
0
32
126
2.70
5.89
3.7
3.1
—
—
—
0
0
185
1382
1.72
5.82
7.2
6.4
1.21
1.22
mmol/l
0.52
142
1168
56
288
2.13
5.72
3.0
2.6
1.85
1.79
%
0.15
47
267
207
2495
0.58
5.60
24.2
16.5
333.04
332.76
g/l
0.19
207
2485
14
24
6.03
5.59
1.6
1.1
—
—
—
0
0
182
1365
1.70
5.55
7.7
5.7
57.05
56.81
%
0.09
173
1291
184
1385
1.70
5.52
8.1
5.9
28.73
28.19
%
0.27
175
1311
152
1116
1.64
4.82
4.4
3.5
45.98
42.73
ng/l
0.07
108
756
207
1642
1.64
4.81
3.9
4.4
6.55
6.72
mmol/l
0.66
196
1545
171
1300
1.62
4.67
17.9
11.0
1.19
1.21
inr
0.14
43
400
171
1303
1.61
4.61
7.9
5.7
0.66
0.72
%
0.89
163
1220
94
615
1.72
4.58
2.2
2.0
3.30
3.28
mg/l
0.03
82
531
175
1348
1.60
4.46
7.7
5.8
2.77
2.89
%
0.30
166
1266
186
1462
1.58
4.29
7.1
5.8
1.99
1.89
e9/l
0.32
167
1318
49
269
1.96
4.18
7.0
4.1
—
—
—
0
0
174
1354
1.57
4.15
8.5
6.1
8.48
8.59
%
0.18
166
1277
121
865
1.61
4.14
3.2
2.2
—
—
—
0
0
219
1800
1.58
4.08
4.8
4.1
9.00
2244.00
e6/l
—
5
29
71
445
1.75
3.99
3.2
3.3
0.81
0.82
mmol/l
0.36
66
418
186
1479
1.55
3.97
7.6
6.1
0.19
0.19
e9/l
0.04
162
1323
173
1356
1.55
3.92
8.7
6.3
—
—
—
0
0
101
701
1.62
3.86
5.3
4.0
—
—
—
0
0
180
1431
1.53
3.78
7.4
5.8
0.56
0.57
e9/l
0.29
159
1261
180
1432
1.53
3.76
7.4
5.8
0.03
0.04
e9/l
2.45
159
1264
10
20
5.11
3.71
1.0
1.3
—
—
—
0
0
59
367
1.73
3.39
2.8
2.2
22.72
22.39
%
0.07
53
316
127
962
1.50
3.21
4.0
3.2
2.33
2.36
mmol/l
1.62
109
854
63
406
1.67
3.18
1.6
1.8
29.48
29.63
s
0.09
63
395
82
566
1.59
3.15
2.5
2.4
4.31
6.88
e6/l
0.97
71
513
201
1677
1.47
3.09
12.6
9.4
4.04
3.97
e9/l
0.13
176
1484
7
12
5.93
3.03
2.9
2.3
—
—
—
0
0
89
633
1.55
2.99
1.7
1.5
22.37
21.65
nmol/l
0.16
68
533
40
230
1.84
2.99
4.2
3.6
1.24
1.23
mmol/l
0.35
32
203
87
620
1.54
2.89
1.5
1.7
1.24
1.11
mg/l
0.08
59
477
112
848
1.47
2.78
4.3
3.8
—
—
—
0
0
137
1094
1.42
2.51
2.2
1.9
108.02
96.78
pmol/l
1.41
74
551
77
553
1.50
2.45
2.5
2.6
555.81
543.24
mosm/kgh2o
0.17
62
480
110
851
1.43
2.39
4.0
3.6
7.40
7.40
ph
0.30
26
162
46
296
1.64
2.35
4.5
7.7
0.92
1.36
mmol/l
0.22
38
246
9
28
3.27
2.32
2.0
1.1
—
—
—
0
0
100
764
1.43
2.32
2.8
2.5
3664.08
7257.05
umol/l
0.46
84
658
114
892
1.41
2.31
2.4
2.5
62.82
56.80
u/l
0.45
102
825
156
1297
1.37
2.17
3.1
2.4
—
—
—
0
0
14
61
2.35
2.17
1.9
5.1
—
—
—
0
0
41
262
1.64
2.16
2.8
1.9
356.44
374.83
nmol/l
0.26
36
247
147
1213
1.37
2.14
5.5
4.5
34.85
36.07
g/l
1.50
135
1141
12
50
2.45
2.05
1.2
2.2
—
—
—
0
0
17
320
0.51
2.04
1.7
1.4
—
—
—
0
0
32
195
1.71
2.01
3.9
2.5
4.00
5.85
e9/l
0.69
26
164
65
470
1.47
2.00
2.1
1.7
1120.69
1228.12
nmol/l
0.44
48
355
17
84
2.08
1.99
1.6
4.3
135.40
26.81
mg/l
—
10
65
17
84
2.08
1.99
1.6
4.3
35.35
41.17
mg/l
—
10
66
152
1272
1.35
1.99
11.1
9.4
0.00
0.00
e9/l
0.58
125
1053
10
39
2.61
1.95
1.2
1.9
—
—
—
0
0
250
2261
1.38
1.92
8.8
7.5
79.26
77.57
u/l
0.20
234
2111
46
312
1.55
1.91
1.8
1.6
—
—
—
0
0
44
296
1.56
1.89
1.6
1.6
—
—
—
0
0
35
225
1.62
1.82
2.4
2.3
5.84
7.86
ug/l
0.46
29
202
240
2174
1.33
1.71
4.7
4.0
13.27
11.40
mm/h
0.84
217
2003
176
1528
1.31
1.70
7.3
6.3
10.25
10.83
umol/l
0.50
164
1448
6
146
0.40
1.68
2.3
3.4
—
—
—
0
0
6
19
3.19
1.67
1.0
1.2
—
—
—
0
0
6
19
3.19
1.67
2.0
1.4
—
—
—
0
0
19
105
1.86
1.66
5.3
3.5
0.50
0.15
g/l
—
8
44
11
49
2.29
1.65
1.3
1.6
—
—
—
0
0
5
14
3.61
1.62
1.0
1.2
—
—
—
0
0
16
85
1.92
1.57
2.3
2.2
1955.84
373.55
ug/l
0.62
16
78
29
185
1.62
1.57
2.9
2.4
—
—
—
0
0
31
202
1.59
1.55
3.7
3.5
92.83
75.26
ng/l
0.40
24
180
5
15
3.37
1.53
2.6
3.5
17.60
16.41
mu/l
—
5
15
5
15
3.37
1.53
1.0
1.1
—
—
—
0
0
5
128
0.38
1.52
1.2
1.1
—
—
—
0
0
0
45
0.00
1.51
0.0
2.5
—
—
—
0
0
7
29
2.44
1.40
4.9
3.0
—
—
—
0
0
6
23
2.64
1.37
1.0
1.3
—
—
—
0
0
23
144
1.64
1.36
2.3
1.5
—
—
—
0
0
11
54
2.07
1.34
1.1
1.5
—
—
—
0
0
15
83
1.84
1.33
2.0
2.6
1.18
1.48
mg/l
1.25
15
77
34
235
1.50
1.33
3.8
3.3
—
—
—
0
0
23
145
1.63
1.33
2.4
2.4
—
—
—
0
0
19
114
1.71
1.31
1.2
1.3
—
—
—
0
0
317
3039
1.48
1.29
18.2
12.1
—
—
—
0
0
11
55
2.03
1.28
1.7
1.6
—
—
—
0
0
6
25
2.42
1.25
1.5
1.7
32.10
40.69
%
—
6
25
36
256
1.45
1.24
5.0
8.1
124.00
123.24
g/l
0.07
36
249
36
256
1.45
1.24
1.5
1.4
—
—
—
0
0
11
56
2.00
1.23
3.4
2.6
1.67
3.23
mmol/l
—
6
35
304
2898
1.39
1.23
18.8
12.8
23.77
21.73
mg/l
0.44
255
2263
8
37
2.19
1.22
2.9
3.7
327.25
371.35
umol/l
—
8
31
26
173
1.54
1.22
3.2
5.0
—
—
—
0
0
5
19
2.65
1.22
1.2
1.3
—
—
—
0
0
6
26
2.33
1.19
2.0
2.5
—
—
—
0
0
101
849
1.27
1.18
3.4
2.9
402.60
117.06
e6/l
0.34
82
648
5
20
2.52
1.15
1.2
1.4
—
—
—
0
0
238
2208
1.25
1.12
4.4
3.9
14.90
14.71
pmol/l
0.49
213
2001
90
751
1.27
1.12
3.4
2.7
—
—
—
0
0
53
412
1.34
1.11
1.3
1.2
—
—
—
0
0
5
21
2.40
1.09
26.2
16.9
1271.60
1628.90
nmol/l
—
5
21
5
21
2.40
1.09
15.8
11.4
751.40
971.95
nmol/l
—
5
21
90
754
1.26
1.08
3.8
3.7
0.00
0.02
estimate
0.69
35
258
7
33
2.14
1.06
1.1
1.0
—
—
—
0
0
71
579
1.28
1.06
1.6
1.7
502.72
445.52
pmol/l
0.56
50
488
9
48
1.90
1.01
8.4
3.1
4.53
4.74
e9/l
—
9
48
7
35
2.02
1.00
1.1
1.2
—
—
—
0
0
9
49
1.86
0.99
8.7
3.5
57.56
58.59
%
—
9
49
34
251
1.39
0.98
1.3
1.4
—
—
—
0
0
0
29
0.00
0.98
0.0
1.2
—
—
—
0
0
32
234
1.40
0.98
5.1
4.7
0.00
0.14
%
2.18
14
72
7
36
1.96
0.97
1.9
2.3
—
—
—
0
0
21
141
1.52
0.97
5.9
8.6
—
—
—
0
0
135
1195
1.21
0.96
2.5
2.2
78.45
76.45
nmol/l
0.32
117
1067
34
252
1.39
0.96
5.1
4.6
0.88
0.87
%
0.00
16
91
98
842
1.23
0.94
2.9
2.8
—
—
—
0
0
9
52
1.75
0.93
1.0
1.1
—
—
—
0
0
131
1160
1.21
0.93
2.0
2.0
—
—
—
0
0
6
28
2.16
0.92
1.5
2.8
—
—
—
0
0
114
998
1.21
0.91
3.8
3.4
63.76
88.79
e6/l
0.27
84
705
8
42
1.93
0.89
1.1
1.4
—
—
—
0
0
6
30
2.02
0.87
1.0
1.1
—
—
—
0
0
210
1950
1.19
0.87
4.5
4.1
—
—
—
0
0
27
197
1.40
0.85
1.3
1.6
—
—
—
0
0
8
45
1.80
0.85
1.1
1.4
—
—
—
0
0
11
65
1.71
0.83
1.3
1.6
—
—
—
0
0
27
198
1.39
0.83
1.2
1.4
—
34.09
—
0
12
8
46
1.76
0.83
1.0
1.0
—
—
—
0
0
6
32
1.89
0.82
1.7
1.8
—
—
—
0
0
6
33
1.83
0.79
1.7
1.8
92.32
90.76
%
—
6
33
0
26
0.00
0.78
0.0
1.5
—
280.59
—
0
17
21
149
1.44
0.77
1.1
1.1
—
132.20
—
0
5
5
24
2.10
0.75
1.4
1.1
185.60
415.58
nmol/l
—
5
19
30
229
1.34
0.74
4.6
4.6
0.33
0.50
%
0.33
15
73
9
55
1.65
0.74
1.7
2.3
—
—
—
0
0
9
55
1.65
0.74
3.8
2.3
—
—
—
0
0
7
38
1.86
0.74
1.0
1.2
—
—
—
0
0
42
337
1.28
0.73
1.2
1.2
—
—
—
0
0
14
92
1.54
0.73
1.4
1.6
—
—
—
0
0
5
25
2.01
0.73
1.0
1.3
—
—
—
0
0
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
311
3021
1.28
0.69
21.0
14.5
139.35
139.74
mmol/l
1.78
302
2952
101
899
1.17
0.66
3.2
3.1
7.94
7.58
mmol/l
0.26
80
763
71
614
1.20
0.64
3.8
3.7
1.02
1.02
kg/l
0.05
12
84
13
88
1.50
0.61
1.2
1.7
—
—
—
0
0
0
20
0.00
0.60
0.0
2.4
—
4.03
—
0
20
0
21
0.00
0.60
0.0
1.7
—
73.62
—
0
21
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
298
2891
1.21
0.60
5.1
4.5
5.95
5.95
mmol/l
0.02
258
2660
13
89
1.48
0.59
1.2
1.7
—
—
—
0
0
13
89
1.48
0.59
1.2
1.7
—
—
—
0
0
42
348
1.24
0.58
1.4
1.4
—
—
—
0
0
39
321
1.24
0.57
1.4
1.5
—
—
—
0
0
8
54
1.49
0.57
1.4
1.1
—
—
—
0
0
8
54
1.49
0.57
1.4
1.1
—
—
—
0
0
263
2529
1.16
0.57
19.3
15.6
30.99
14.99
%
0.52
256
2493
311
3034
1.24
0.56
21.0
14.6
3.98
3.97
mmol/l
0.39
302
2959
14
193
0.71
0.55
4.2
2.6
—
—
—
0
0
12
82
1.48
0.55
1.1
1.2
—
—
—
0
0
277
2677
1.17
0.54
5.3
4.6
1.99
2.33
mu/l
0.34
245
2446
86
768
1.16
0.54
3.5
2.8
0.27
0.50
e6/l
0.97
68
572
9
61
1.49
0.54
3.3
6.5
105.89
105.80
mmol/l
—
9
54
9
61
1.49
0.54
3.3
6.5
9.89
10.76
mmol/l
—
9
54
59
511
1.19
0.54
4.0
2.6
2.46
2.45
mmol/l
0.25
51
455
73
644
1.17
0.54
1.4
1.3
0.48
1.19
u/ml
2.25
18
181
6
39
1.55
0.53
1.2
1.1
—
—
—
0
0
212
2016
1.13
0.51
3.6
3.2
52.70
47.42
u/l
0.39
199
1896
90
810
1.15
0.51
3.1
3.1
—
—
—
0
0
28
226
1.26
0.50
5.4
4.8
0.00
0.16
%
0.66
11
63
21
163
1.31
0.49
1.4
1.2
—
—
—
0
0
7
47
1.50
0.48
1.0
1.1
—
—
—
0
0
45
388
1.18
0.44
2.1
1.7
—
—
—
0
0
27
221
1.24
0.44
2.1
2.6
—
18.92
—
0
13
40
342
1.19
0.43
1.9
2.2
854.00
117.24
ug/g
0.58
28
275
5
31
1.62
0.43
3.4
3.4
—
—
—
0
0
129
1204
1.11
0.41
3.1
2.6
154.46
117.13
ug/l
1.34
117
1110
0
15
0.00
0.41
0.0
1.5
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
7.42
—
0
15
0
15
0.00
0.41
0.0
1.4
—
22.26
—
0
15
25
205
1.24
0.40
7.4
8.0
—
—
—
0
0
122
1137
1.11
0.40
3.2
3.3
6.39
5.87
ph
—
9
102
21
169
1.26
0.39
5.4
8.0
26.38
24.87
mmol/l
1.49
21
160
5
35
1.43
0.39
1.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
9.42
—
0
19
47
412
1.16
0.39
1.2
1.4
937.14
542.92
titre
—
7
96
12
89
1.36
0.38
1.3
1.7
—
—
—
0
0
82
749
1.12
0.38
1.4
1.3
—
—
—
0
0
13
98
1.34
0.38
3.5
5.2
—
—
—
0
0
64
577
1.13
0.37
1.5
1.5
2.35
2.46
g/l
0.20
38
354
11
81
1.37
0.36
3.5
6.5
1.34
1.16
mmol/l
0.42
11
71
217
2092
1.10
0.35
4.2
3.7
—
—
—
0
0
6
46
1.31
0.33
1.3
1.6
—
—
—
0
0
11
83
1.34
0.32
1.3
1.7
—
—
—
0
0
7
98
0.71
0.31
9.9
6.9
—
—
—
0
0
38
335
1.15
0.30
5.3
6.6
104.63
103.76
mmol/l
0.61
38
335
12
93
1.30
0.30
1.3
1.2
—
—
—
0
0
149
1420
1.09
0.30
3.6
3.4
0.00
0.00
estimate
0.50
36
283
291
2857
1.11
0.28
4.5
4.0
1.43
1.31
mmol/l
0.61
257
2635
33
291
1.15
0.27
1.2
1.5
—
—
—
0
0
91
853
1.09
0.27
3.4
3.2
1017.68
282.13
mg/l
0.34
49
543
49
445
1.12
0.26
3.3
2.7
1.50
2.16
e6/l
0.57
30
235
5
74
0.67
0.26
2.4
1.9
235.20
249.38
pmol/l
—
5
69
77
825
0.91
0.26
1.8
1.7
1.32
1.43
mmol/l
0.63
54
702
17
202
0.83
0.25
1.5
1.5
—
—
—
0
0
78
730
1.09
0.24
8.4
6.8
—
—
—
0
0
5
38
1.32
0.23
1.0
1.3
—
—
—
0
0
33
295
1.13
0.23
5.1
4.4
15.64
20.47
ug/l
0.11
26
249
5
41
1.22
0.22
1.0
1.3
0.50
0.53
nmol/l
—
5
35
45
490
0.91
0.21
2.7
2.8
0.60
0.74
ug/l
0.81
27
281
5
42
1.19
0.21
3.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
44
403
1.11
0.21
2.3
1.8
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
95
902
1.07
0.21
4.2
3.8
7.24
8.33
mg/mmol
0.13
53
560
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
10
80
1.26
0.20
2.9
2.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
193.96
—
0
14
7
60
1.17
0.18
1.6
1.5
—
—
—
0
0
5
70
0.71
0.17
3.2
2.5
26.62
25.16
mmol/l
—
5
70
8
68
1.18
0.16
1.4
1.2
—
—
—
0
0
14
162
0.86
0.16
1.4
1.7
—
—
—
0
0
148
1437
1.05
0.16
3.7
3.5
0.00
0.01
estimate
0.50
32
253
8
73
1.10
0.16
1.4
1.2
—
—
—
0
0
324
3263
0.90
0.15
28.7
19.2
133.66
136.79
g/l
3.32
319
3215
299
2959
1.07
0.15
5.0
4.5
4.79
4.77
mmol/l
0.18
269
2761
324
3262
0.90
0.14
28.6
19.1
4.42
4.53
e12/l
3.29
318
3168
31
286
1.09
0.14
1.4
1.6
—
—
—
0
0
24
219
1.10
0.13
4.2
3.4
—
—
—
0
0
324
3261
0.91
0.13
28.5
19.0
30.49
30.34
pg
0.89
319
3217
324
3261
0.91
0.13
28.6
19.1
6.72
6.49
e9/l
0.94
319
3166
324
3260
0.91
0.12
28.4
19.1
39.78
40.63
%
1.81
310
3068
24
221
1.09
0.11
1.5
1.2
—
—
—
0
0
22
239
0.92
0.11
3.8
3.4
5.58
5.75
kpa
0.36
22
233
280
2773
1.05
0.11
5.9
5.6
39.13
39.70
mmol/mol
0.53
250
2594
10
115
0.87
0.11
1.1
1.0
—
—
—
0
0
24
222
1.09
0.10
1.7
1.4
—
—
—
0
0
145
1421
1.03
0.09
4.8
4.7
0.00
0.00
estimate
0.50
34
269
11
124
0.88
0.09
1.5
1.9
—
—
—
0
0
297
2949
1.05
0.08
5.0
4.5
1.45
1.48
mmol/l
0.62
264
2732
6
71
0.84
0.07
3.5
2.5
—
—
—
0
0
26
276
0.94
0.07
2.1
2.3
35.33
31.51
u/l
0.11
21
240
8
77
1.04
0.07
1.0
1.1
—
—
—
0
0
300
3016
0.96
0.06
5.2
5.0
2.82
2.84
mmol/l
0.16
268
2791
52
504
1.04
0.06
3.5
3.6
260.71
248.09
ng/l
0.02
38
386
32
334
0.95
0.05
1.3
1.3
—
—
—
0
0
20
190
1.06
0.04
1.3
1.3
—
—
—
0
0
65
641
1.02
0.02
3.6
3.4
—
—
—
0
0
316
3153
1.02
0.01
12.9
10.3
27.04
27.17
u/l
0.05
297
3052
315
3143
1.02
0.01
20.5
15.2
78.02
75.44
umol/l
0.76
315
3143
12
114
1.05
0.00
3.1
5.3
1.02
0.92
%
0.27
12
106
83
836
0.99
0.00
3.7
4.2
1.65
2.28
ug/l
0.71
69
745
53
528
1.00
0.00
1.4
1.3
69.76
38.90
iu/ml
0.38
16
173
50
501
1.00
0.00
1.3
1.3
15.93
12.47
u/ml
0.14
19
205
114
1144
0.99
0.00
3.0
2.9
—
—
—
0
0
12
115
1.05
0.00
2.8
5.2
1.96
1.61
%
0.62
12
106
14
145
0.96
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
9
95
0.95
-0.00
1.9
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
0.98
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
1.82
—
0
5
8
88
0.91
-0.00
1.4
2.2
32.77
38.84
g/l
—
8
81
5
55
0.91
-0.00
5.6
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.6
—
—
—
0
0
5
51
0.98
-0.00
1.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.9
—
1.18
—
0
8
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
90
1.00
-0.00
1.6
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.1
—
5.81
—
0
9
5
59
0.85
-0.00
3.4
2.4
7.30
7.96
kpa
—
5
59

Mortality – FinRegistry

↥

Association

Association between endpoint AB1_ATYPICAL_CNS_VIRUS and mortality.

Females

Parameter HR [95% CI] p-value
AB1_ATYPICAL_CNS_VIRUS 4.8 [2.84, 8.11] < 0.001
Birth year 0.991 [0.98, 1.0] 0.049

During the follow-up period (1.1.1998 — 31.12.2019), 147 out of 229 females with AB1_ATYPICAL_CNS_VIRUS died.

Males

Parameter HR [95% CI] p-value
AB1_ATYPICAL_CNS_VIRUS 8.359 [4.15, 16.85] < 0.001
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 127 out of 186 males with AB1_ATYPICAL_CNS_VIRUS died.

Mortality risk

Mortality risk for people of age

years, who have AB1_ATYPICAL_CNS_VIRUS.

N-year risk Females Males
1 0.359% 1.382%
5 2.327% 8.753%
10 5.99% 22.142%
15 11.43% 38.663%
20 19.64% 57.268%

Relationships between endpoints

↥

Index endpoint: AB1_ATYPICAL_CNS_VIRUS – Atypical virus infections of central nervous system

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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