≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback

Benign neoplasm: Endocrine pancreas

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_ENDOCRINE_PANCREAS

pancreatic neuroendocrine tumor: Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma) (see these terms).

Suggest a new description

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D13.7&
  • Hospital discharge: ICD-9 — 2117
  • Cause of death: ICD-10 — D13.7&
  • Cause of death: ICD-9 — 2117

2 out of 7 registries used, show all original rules.

201

4. Check minimum number of events

None

201

5. Include endpoints

None

201

6. Filter based on genotype QC (FinnGen only)

201

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum partis endocrinae pancreatis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 826 449 372
Only index persons 764 421 343
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.02 0.01
Median age at first event (years)
Whole population 64.35 64.03 64.77
Only index persons 63.60 62.65 64.76

-FinnGen-

Key figures

All Female Male
Number of individuals 201 88 113
Unadjusted period prevalence (%) 0.04 0.03 0.05
Median age at first event (years) 63.92 60.64 66.46

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
178
Matched controls
1780
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
+∞
240.9
172
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
85.0
69.2
75
15
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
36.1
33.0
42
15
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
22.6
24.2
35
19
JN3BD
NOMESCO Finland
Extensive abdominal CT
7.3
21.5
57
108
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
87.2
21.2
23
*
JLC10
NOMESCO Finland
Distal pancreatectomy
118.3
20.0
21
*
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
10.4
16.6
33
38
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
+∞
15.9
15
*
A09AA02
ATC
multienzymes (lipase, protease etc.)
18.3
15.8
24
15
WX302
NOMESCO Finland
Thoracal epidural anesthesy
8.1
15.5
36
54
JLC00
NOMESCO Finland
Excision of lesion of pancreas
+∞
14.8
14
*
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
58.2
14.1
16
*
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
81.2
13.8
15
*
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
37.3
13.8
17
5
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
+∞
13.7
13
*
JN3AD
NOMESCO Finland
Abdominal CT examination
6.6
13.5
36
66
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
7.0
13.1
33
56
E16.10
ICD-10 Finland
Hyperinsulinism
+∞
12.6
12
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
19.8
12.3
18
10
K86.2
ICD-10 Finland
Cyst of pancreas
29.1
12.3
16
6
JLC11
NOMESCO Finland
Laparoscopic distal pancreatectomy
+∞
11.6
11
*
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
37.7
11.4
14
*
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
37.7
11.4
14
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.1
11.1
88
430
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
46.5
11.1
13
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
5.6
11.0
33
70
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
19.4
10.9
16
9
WX408
NOMESCO Finland
General anesthesy, balanced
3.0
9.7
71
323
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
+∞
9.5
9
*
JN4CD
NOMESCO Finland
Very extensive body CT
6.6
9.1
23
39
JN4AD
NOMESCO Finland
Body CT examination
4.6
8.6
30
75
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
8.6
8.6
18
23
JLC30
NOMESCO Finland
Pancreatoduodenectomy
29.1
8.6
11
*
JN4BD
NOMESCO Finland
Extensive body CT
3.7
8.2
37
118
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
83.4
7.5
8
*
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
83.4
7.5
8
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.1
7.2
41
156
JN1AD
NOMESCO Finland
CT examination of upper part of abdomen
41.7
6.8
8
*
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
41.7
6.8
8
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
12.9
6.7
11
9
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
6.7
98
623
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
6.6
67
352
E34.0
ICD-10 Finland
Carcinoid syndrome
72.3
6.5
7
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.6
6.4
28
87
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
11.6
6.4
11
10
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
18.8
6.3
9
5
V03AH01
ATC
diazoxide; systemic
+∞
6.3
6
*
JMA10
NOMESCO Finland
Transabdominal total splenectomy
27.8
6.3
8
*
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
27.8
6.3
8
*

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
80
199
6.02
32.77
3.1
4.8
2.9
27.2
ug/l
0.63
59
170
37
48
9.22
27.76
1.8
1.5
229.1
296.6
ug/g
0.89
28
29
46
80
7.16
26.77
2.3
3.2
34.5
526.2
u/ml
0.69
40
66
124
573
4.04
20.99
3.7
2.6
60.5
55.0
u/l
0.48
118
528
151
806
4.51
20.60
8.0
5.9
1.2
1.2
mmol/l
0.29
143
739
144
770
4.07
18.94
7.3
4.9
34.6
35.3
g/l
0.73
139
733
155
882
4.31
18.36
11.0
6.9
1.2
1.2
mmol/l
0.21
121
743
139
740
3.85
18.08
15.3
10.0
1.3
1.3
inr
0.06
53
233
113
546
3.44
16.74
4.8
4.0
7.4
7.4
ph
0.34
31
122
20
5
44.06
16.67
4.5
1.0
12.2
8.4
mu/l
—
20
5
54
164
4.13
16.20
2.7
2.5
304.7
33.5
u/l
0.55
46
136
48
134
4.39
16.10
4.6
3.9
89.0
81.2
ng/l
0.28
41
119
19
25
8.29
13.80
1.6
1.2
—
—
—
0
0
19
25
8.29
13.80
1.4
1.2
—
—
nmol/l
—
0
0
158
1040
3.43
12.27
8.0
4.9
7.0
6.9
mmol/l
0.29
152
968
48
170
3.40
11.19
1.6
1.4
—
—
—
0
0
87
441
2.72
10.62
4.0
3.9
91.9
88.2
%
0.59
87
435
12
14
9.05
9.44
2.2
1.6
—
—
—
0
0
43
161
3.13
9.04
4.4
4.2
1.2
1.2
mmol/l
0.09
36
149
64
306
2.60
8.49
3.1
3.3
0.8
0.8
mmol/l
0.54
64
287
92
526
2.38
8.24
3.2
3.1
1.5
0.5
e6/l
0.32
71
395
89
504
2.37
8.12
3.3
3.0
—
—
—
0
0
49
210
2.76
8.02
8.2
7.4
5.1
5.1
kpa
0.22
49
203
54
244
2.66
7.98
6.9
7.0
106.4
103.8
mmol/l
4.74
54
237
48
210
2.69
7.52
8.3
7.4
14.0
12.1
kpa
1.32
48
204
45
191
2.75
7.47
8.5
7.9
96.2
96.0
%
0.06
45
186
48
214
2.63
7.23
2.5
3.4
9.6
9.2
umol/l
0.04
41
188
94
572
2.21
6.97
3.4
3.3
215.0
60.0
e6/l
0.46
72
441
24
75
3.50
6.67
4.5
4.2
—
—
—
0
0
38
157
2.75
6.60
4.8
4.0
—
—
—
0
0
151
1128
2.36
6.53
4.9
4.5
—
379.9
—
0
23
92
567
2.15
6.49
4.2
4.2
8.6
8.1
mg/mmol
0.03
54
370
90
559
2.10
6.14
3.2
3.2
7.0
7.7
mmol/l
0.96
77
455
17
44
4.13
6.12
4.9
2.5
2.8
2.3
mmol/l
0.34
11
26
87
538
2.09
5.97
3.1
3.4
59.6
167.0
mg/l
0.44
51
356
102
680
2.02
5.60
2.4
2.2
—
—
—
0
0
17
48
3.78
5.45
5.3
2.6
7.4
7.4
ph
0.16
17
43
48
242
2.29
5.44
1.6
1.3
—
—
—
0
0
90
579
2.00
5.41
4.7
3.3
2.4
2.3
mmol/l
1.24
84
507
98
650
1.99
5.40
4.0
3.8
59.9
76.8
e6/l
0.17
74
472
86
549
1.99
5.25
2.9
2.4
—
—
—
0
0
119
851
1.98
5.21
4.4
3.8
0.0
0.0
estimate
0.00
38
184
119
864
1.92
4.84
4.4
3.9
0.0
0.0
estimate
0.00
36
177
31
136
2.51
4.74
4.5
5.1
0.0
0.0
%
—
8
40
75
471
1.94
4.70
1.7
1.7
1.5
1.3
mmol/l
0.57
62
382
42
214
2.22
4.60
1.4
1.7
—
—
—
0
0
117
854
1.89
4.59
5.9
5.2
0.0
0.0
estimate
0.00
36
185
154
1232
2.07
4.59
5.4
4.2
—
—
—
0
0
8
8
10.35
4.56
3.0
1.6
—
—
—
0
0
155
1246
2.07
4.51
4.4
3.7
15.0
14.9
pmol/l
0.07
143
1108
30
136
2.42
4.28
4.6
4.9
0.8
0.3
%
—
8
34
131
1007
1.86
4.20
10.2
9.3
4.5
4.2
e9/l
0.82
118
881
14
42
3.51
4.12
4.8
3.4
—
—
—
0
0
9
14
6.67
4.03
1.0
1.3
—
—
—
0
0
108
790
1.79
4.01
16.2
10.5
0.0
0.0
e9/l
0.50
93
646
47
265
2.01
3.93
3.0
2.5
21.8
22.7
%
0.13
40
232
67
426
1.86
3.93
8.3
7.1
—
—
—
0
0
30
142
2.31
3.89
4.8
5.0
0.1
0.2
%
—
9
47
56
338
1.91
3.85
4.1
2.9
2.5
2.5
mmol/l
1.67
50
292
188
1669
2.95
3.78
6.5
4.8
6.5
6.1
mmol/l
2.14
181
1522
100
726
1.75
3.72
4.4
4.0
39.7
47.4
ng/l
0.24
76
539
67
433
1.82
3.70
2.4
2.0
3.4
3.2
mg/l
0.26
62
374
84
581
1.77
3.70
5.6
5.6
—
—
—
0
0
46
263
1.97
3.69
2.3
1.9
—
—
—
0
0
76
512
1.78
3.65
5.5
4.4
—
—
—
0
0
40
222
2.00
3.48
1.6
1.2
—
—
—
0
0
78
537
1.74
3.44
2.0
2.1
177.6
216.0
u/l
0.25
72
504
66
433
1.78
3.44
1.3
1.4
—
—
—
0
0
10
27
3.85
3.40
3.1
4.0
—
—
—
0
0
31
158
2.14
3.37
4.7
4.8
0.8
0.9
%
—
8
53
30
151
2.16
3.37
6.5
8.8
—
—
—
0
0
182
1610
2.38
3.35
8.9
6.2
41.8
40.6
mmol/mol
0.86
176
1498
6
7
8.79
3.28
2.7
1.4
26.7
30.1
umol/l
—
6
7
176
1545
2.12
3.16
5.2
4.6
1.9
1.9
mu/l
0.09
162
1379
12
39
3.21
3.14
4.6
3.2
52.5
60.5
%
0.98
12
39
25
120
2.24
3.14
11.8
6.6
25.0
24.6
mmol/l
0.23
25
114
188
1696
2.68
3.14
25.0
15.6
33.1
23.5
mg/l
2.22
175
1356
61
403
1.74
3.06
5.0
5.4
—
—
—
0
0
143
1185
1.72
3.00
4.8
4.3
—
—
—
0
0
66
448
1.70
3.00
1.5
1.5
21.1
21.3
nmol/l
0.04
59
377
70
484
1.68
2.96
4.9
4.1
0.0
0.0
estimate
0.00
32
179
21
96
2.33
2.95
12.7
9.5
—
—
—
0
0
35
197
1.94
2.92
1.5
1.4
—
—
—
0
0
21
97
2.30
2.89
7.8
10.2
23.2
24.5
mmol/l
0.98
21
91
69
479
1.67
2.86
2.3
3.0
390.5
9106.6
umol/l
2.59
54
406
112
878
1.62
2.86
5.7
5.7
0.7
0.6
e9/l
1.25
101
761
112
881
1.61
2.80
5.7
5.7
0.0
0.0
e9/l
0.55
101
766
52
338
1.73
2.73
2.5
1.7
1315.2
1240.1
nmol/l
0.22
43
262
72
514
1.62
2.65
3.6
3.2
—
—
—
0
0
25
129
2.07
2.64
8.9
4.2
—
—
—
0
0
18
81
2.34
2.63
2.4
2.0
8.8
5.7
ug/l
0.20
18
75
59
401
1.67
2.63
2.1
1.7
454.8
442.3
pmol/l
0.15
46
324
11
38
3.00
2.62
3.6
2.7
3.5
4.9
e9/l
1.46
11
38
8
20
4.12
2.59
1.3
1.2
—
—
—
0
0
17
75
2.38
2.59
2.8
3.0
—
—
—
0
0
69
490
1.62
2.58
4.1
3.6
—
—
—
0
0
112
893
1.57
2.56
5.7
5.8
1.9
1.9
e9/l
0.09
102
795
113
903
1.57
2.55
5.7
5.9
0.2
0.2
e9/l
0.19
102
802
191
1763
2.68
2.52
32.3
18.2
4.0
4.0
mmol/l
0.62
191
1719
191
1764
2.66
2.50
32.4
18.0
139.6
139.7
mmol/l
0.10
191
1720
91
701
1.54
2.37
3.3
2.6
164.4
145.3
ug/l
0.23
85
644
29
167
1.86
2.26
1.6
1.5
—
—
—
0
0
192
1803
2.45
2.23
31.7
18.5
86.4
81.1
umol/l
0.78
192
1803
29
169
1.84
2.19
2.9
2.9
60.6
72.1
e9/l
1.15
24
131
148
1283
1.58
2.15
4.6
4.2
13.0
12.4
mm/h
0.18
135
1170
55
387
1.58
2.09
4.2
3.7
—
—
—
0
0
190
1773
2.31
2.02
25.9
14.7
—
—
—
0
0
14
64
2.28
1.99
5.2
3.5
3.8
3.9
mmol/l
0.24
14
56
53
374
1.57
1.99
1.6
1.8
2.4
1.5
mg/l
0.52
41
292
50
349
1.58
1.96
1.3
1.2
0.9
0.9
u/ml
0.03
12
91
8
27
3.04
1.96
4.0
1.6
15.2
15.6
ug/l
—
8
27
10
39
2.65
1.95
4.4
2.6
—
—
—
0
0
7
24
2.98
1.74
2.3
4.4
2.6
1.0
%
—
7
19
5
13
3.91
1.72
1.6
1.3
—
—
—
0
0
8
31
2.64
1.68
2.0
2.9
—
—
—
0
0
71
555
1.43
1.59
4.7
4.2
—
—
—
0
0
22
132
1.75
1.53
1.5
2.4
—
—
—
0
0
90
738
1.40
1.53
2.3
1.9
91.1
95.8
pmol/l
0.48
53
391
18
102
1.84
1.50
1.3
1.2
—
—
—
0
0
12
59
2.10
1.47
1.3
1.1
—
—
—
0
0
164
1501
1.50
1.43
22.9
16.0
39.2
40.0
%
0.40
96
1045
44
320
1.48
1.42
1.4
1.5
2.4
2.7
g/l
0.64
27
195
45
331
1.46
1.37
5.3
3.9
323.3
141.8
ng/l
0.57
38
271
12
61
2.03
1.36
2.0
4.3
32.2
29.2
mg/l
—
7
48
12
61
2.03
1.36
2.0
4.3
38.2
150.4
mg/l
—
7
48
9
45
2.05
1.25
2.1
5.0
—
—
—
0
0
6
26
2.35
1.19
1.2
1.2
—
—
—
0
0
7
31
2.30
1.11
1.9
2.0
31.1
33.1
pg
—
7
31
5
21
2.41
1.09
1.0
1.1
—
—
—
0
0
15
93
1.66
0.97
2.5
2.6
—
—
—
0
0
25
176
1.48
0.96
4.5
4.0
—
—
—
0
0
7
37
1.92
0.95
4.0
2.8
—
—
—
0
0
6
28
2.18
0.92
2.2
2.1
—
—
—
0
0
30
224
1.40
0.86
1.4
1.3
506.7
470.6
titre
—
6
47
11
65
1.73
0.84
1.9
1.7
—
—
—
0
0
14
89
1.62
0.83
1.1
1.2
—
—
—
0
0
8
47
1.73
0.81
1.1
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
2.2
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
23
168
1.42
0.75
3.8
4.1
2.2
2.1
mmol/l
0.04
18
129
5
26
1.95
0.71
3.0
3.4
4.1
4.0
mmol/l
—
5
26
5
26
1.95
0.71
3.0
3.4
—
—
—
0
0
5
26
1.95
0.71
3.0
3.4
108.0
106.2
mmol/l
—
5
26
5
27
1.87
0.69
1.8
2.3
93.6
89.0
%
—
5
27
18
129
1.43
0.66
1.2
1.4
—
—
—
0
0
22
165
1.37
0.64
1.5
1.4
—
—
—
0
0
192
1873
1.56
0.63
39.7
22.7
131.6
136.1
g/l
3.50
192
1845
192
1873
1.56
0.63
39.4
22.5
4.4
4.5
e12/l
2.36
192
1819
192
1873
1.56
0.63
39.4
22.6
6.9
6.7
e9/l
0.93
192
1821
192
1872
1.57
0.63
39.3
22.5
91.4
91.3
fl
0.07
192
1846
192
1872
1.57
0.63
39.3
22.4
30.3
30.4
pg
0.72
192
1845
192
1871
1.58
0.63
39.4
22.6
243.9
240.8
e9/l
0.27
192
1827
20
148
1.39
0.62
4.1
3.9
—
—
—
0
0
0
20
0.00
0.60
0.0
1.1
—
0.1
—
0
6
0
20
0.00
0.60
0.0
1.8
—
480.4
—
0
9
0
20
0.00
0.60
0.0
1.1
—
0.9
—
0
10
0
22
0.00
0.59
0.0
1.0
—
11.0
—
0
13
16
115
1.43
0.58
1.4
1.6
1.0
1.5
g/l
0.50
16
103
6
36
1.69
0.57
2.3
2.1
—
—
—
0
0
13
92
1.44
0.52
4.8
4.4
—
—
—
0
0
26
208
1.29
0.51
1.3
1.4
—
—
—
0
0
7
46
1.54
0.49
1.3
1.2
—
—
—
0
0
7
46
1.54
0.49
4.3
2.9
8.1
7.8
kpa
—
7
41
7
47
1.51
0.48
1.1
1.5
—
—
—
0
0
84
765
1.17
0.47
6.2
5.3
2.3
2.7
ug/l
0.40
76
685
16
122
1.34
0.44
1.1
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
0.9
—
0
8
0
16
0.00
0.41
0.0
1.1
—
2.0
—
0
7
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
65.4
—
0
6
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
—
—
0
0
42
367
1.18
0.39
4.9
4.2
1.0
1.0
kg/l
—
9
42
10
72
1.41
0.37
4.5
2.1
379.6
354.3
ug/l
—
10
66
22
265
0.81
0.37
1.0
1.3
1.4
9.0
u/ml
1.87
12
105
9
71
1.28
0.36
1.1
1.6
—
—
—
0
0
10
73
1.39
0.35
1.8
1.4
—
—
—
0
0
172
1673
1.19
0.34
5.3
4.7
1.4
1.4
mmol/l
1.91
164
1526
173
1684
1.20
0.34
5.5
4.8
4.3
4.5
mmol/l
2.77
165
1544
7
52
1.36
0.31
1.0
1.2
—
—
—
0
0
7
54
1.31
0.30
7.1
5.8
—
—
—
0
0
8
106
0.74
0.30
1.9
1.6
—
—
—
0
0
50
454
1.13
0.29
3.8
3.3
0.9
0.8
ug/l
0.27
41
309
19
160
1.21
0.26
11.3
4.6
—
—
—
0
0
166
1621
1.14
0.25
4.8
4.2
1.4
1.3
mmol/l
1.32
155
1475
8
104
0.76
0.21
2.1
2.2
4.4
3.8
e9/l
—
8
77
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
1.8
—
0
12
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
14
118
1.20
0.19
2.9
2.3
—
—
—
0
0
6
53
1.14
0.19
1.8
1.5
—
—
—
0
0
6
53
1.14
0.19
1.8
3.4
—
—
—
0
0
10
119
0.83
0.16
1.2
1.4
—
—
—
0
0
9
78
1.16
0.15
1.6
1.3
—
—
—
0
0
10
117
0.85
0.13
1.1
1.4
—
—
—
0
0
174
1719
1.09
0.12
6.1
5.3
2.5
2.7
mmol/l
2.20
165
1573
7
65
1.08
0.08
1.0
1.1
—
—
—
0
0
20
214
0.93
0.07
2.3
1.5
—
—
—
0
0
9
87
1.04
0.07
10.1
3.8
—
—
—
0
0
59
600
0.98
0.02
3.5
3.3
—
—
—
0
0
13
134
0.97
0.00
1.4
1.4
—
—
—
0
0
19
187
1.02
0.00
2.3
1.4
—
—
—
0
0
25
245
1.02
0.00
2.2
1.7
—
—
—
0
0
10
98
1.02
0.00
1.3
1.2
35.4
161.7
u/ml
—
10
88
28
282
0.99
0.00
1.1
1.3
10.1
33.4
iu/ml
—
7
99
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
8
89
0.89
0.00
1.4
2.0
1.7
1.5
g/l
—
8
73
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
50
1.00
0.00
1.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
1.2
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_ENDOCRINE_PANCREAS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_ENDOCRINE_PANCREAS 2.501 [1.71, 3.67] < 0.001
Birth year 0.991 [0.98, 1.0] 0.048

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 343 females with CD2_BENIGN_ENDOCRINE_PANCREAS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_ENDOCRINE_PANCREAS 2.53 [1.48, 4.32] < 0.001
Birth year 0.985 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 275 males with CD2_BENIGN_ENDOCRINE_PANCREAS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_ENDOCRINE_PANCREAS.

N-year risk Females Males
1 0.26% 0.423%
5 1.356% 2.896%
10 3.129% 6.819%
15 6.062% 13.219%
20 10.476% 20.537%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_ENDOCRINE_PANCREAS – Benign neoplasm: Endocrine pancreas

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data