≡ Risteys
R13

Documentation Changelog GitHub Contact & Feedback

Benign neoplasm: Endocrine pancreas

DOID EFO Endpoint Browser PheWeb

CD2_BENIGN_ENDOCRINE_PANCREAS

pancreatic neuroendocrine tumor: Pancreatic endocrine tumor, also known as pancreatic neuroendocrine tumor (PNET), describes a group of endocrine tumors originating in the pancreas that are usually indolent and benign, but may have the potential to be malignant. They can be functional, exhibiting a hormonal hypersecretion syndrome, but can be non-functional presenting with non-specific symptoms and include insulinoma, glucagonoma, VIPoma, somatostatinoma (SSoma), PPoma and Zollinger-Ellison syndrome (ZES, or gastrinoma) and other ectopic hormone producing tumors (such as GRFoma) (see these terms).

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D13.7&
  • Hospital discharge: ICD-9 — 2117
  • Cause of death: ICD-10 — D13.7&
  • Cause of death: ICD-9 — 2117

2 out of 7 registries used, show all original rules.

220

4. Check minimum number of events

None

220

5. Include endpoints

None

220

6. Filter based on genotype QC (FinnGen only)

215

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D13
Name in latin
Neoplasma benignum partis endocrinae pancreatis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 826 449 372
Only index persons 764 421 343
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.02 0.01
Median age at first event (years)
Whole population 64.35 64.03 64.77
Only index persons 63.60 62.65 64.76

-FinnGen-

Key figures

All Female Male
Number of individuals 215 97 118
Unadjusted period prevalence (%) 0.05 0.03 0.05
Median age at first event (years) 64.07 61.02 66.57

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
220
Matched controls
2200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D13.7
ICD-10 Finland
Benign neoplasm: Endocrine pancreas
+∞
298.9
213
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
60.1
160.0
96
28
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
45.9
81.8
50
14
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
22.7
60.3
47
26
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
19.4
43.7
36
22
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
16.2
41.8
38
28
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.2
33.1
45
60
JN3BD
NOMESCO Finland
Extensive abdominal CT
6.4
31.6
64
132
JLC10
NOMESCO Finland
Distal pancreatectomy
306.5
27.4
27
*
D13.6
ICD-10 Finland
Benign neoplasm: Pancreas
66.4
25.7
29
5
C25.4
ICD-10 Finland
Malignant neoplasm: Endocrine pancreas
+∞
22.3
21
*
JN3AD
NOMESCO Finland
Abdominal CT examination
4.9
21.0
56
144
JN5ER
NOMESCO Finland
PET-CT of receptors in whole body
40.5
18.0
22
6
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
5.1
17.0
40
92
8240/3-C25.9
ICD-O-3
Neuroendocrine tumor, NOS, of pancreas, NOS
+∞
16.9
16
*
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
20.5
16.4
24
13
JLC00
NOMESCO Finland
Excision of lesion of pancreas
+∞
15.8
15
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.2
15.3
90
391
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.2
15.2
46
129
H01CB03
ATC
lanreotide; parenteral
86.0
14.8
16
*
D44.8
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Pluriglandular involvement
86.0
14.8
16
*
JLC11
NOMESCO Finland
Laparoscopic distal pancreatectomy
+∞
14.7
14
*
E16.10
ICD-10 Finland
Hyperinsulinism
+∞
14.7
14
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.0
14.7
109
538
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
21.8
14.1
20
10
JN1BD
NOMESCO Finland
Extensive CT examination of upper part of abdomen
57.2
14.0
16
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
36.6
13.7
17
5
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
22.9
13.6
19
9
K86.2
ICD-10 Finland
Cyst of pancreas
22.9
13.6
19
9
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
18.2
13.3
20
12
JN4CD
NOMESCO Finland
Very extensive body CT
6.1
13.2
24
43
JN4AD
NOMESCO Finland
Body CT examination
3.8
13.0
45
138
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
12.7
12.6
22
19
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
49.5
12.0
14
*
WX402
NOMESCO Finland
General anaesthesia
3.0
11.9
68
285
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.5
11.7
31
78
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.3
11.5
50
178
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
16.6
11.0
17
11
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
10.9
10.8
20
20
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.9
10.5
34
99
C25.2
ICD-10 Finland
Malignant neoplasm: Tail of pancreas
+∞
10.5
10
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.6
10.5
89
454
130
Kela drug reimbursment
Malignant tumour
3.5
10.5
41
136
JLC30
NOMESCO Finland
Pancreatoduodenectomy
24.8
10.4
14
6
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
16.0
9.7
15
10
ZXE10
NOMESCO Finland
More than one and less than three hours
2.5
9.6
103
581
E21.0
ICD-10 Finland
Primary hyperparathyroidism
13.2
9.5
16
13
E34.0
ICD-10 Finland
Carcinoid syndrome
104.3
9.5
10
*
8249/3-C25.9
ICD-O-3
Neuroendocrine tumor, grade 2 of pancreas, NOS
+∞
9.4
9
*
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
14.5
9.3
15
11
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
9.2
43
159
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
9.0
58
255
JN4BD
NOMESCO Finland
Extensive body CT
3.0
8.7
43
164
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.2
8.6
37
130
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
11.4
8.4
15
14
BBA50
NOMESCO Finland
Total parathyroidectomy
+∞
8.4
8
*
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
18.0
8.2
12
7
D37.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Digestive organ, unspecified
23.0
8.1
11
5
R93.3
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of digestive tract
46.7
7.8
9
*
H01CB02
ATC
octreotide; parenteral
46.7
7.8
9
*
E21.2
ICD-10 Finland
Other hyperparathyroidism
+∞
7.3
7
*
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
20.8
7.2
10
5
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.3
7.0
74
404
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
8.7
6.9
14
17
Z01.8
ICD-10 Finland
Other specified special examinations
2.3
6.5
63
330
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.1
6.5
123
835
JMA10
NOMESCO Finland
Transabdominal total splenectomy
14.9
6.5
10
7
2117X
ICD-9 Finland
Benign neoplasm of other parts of digestive system, Islets of Langerhans[NEOPLASMA BENIGNUM ALIUD INSULARUM LANGERHANS]
+∞
6.3
6
*
BBA70
NOMESCO Finland
Implantation or transplantation of parathyroid gland
+∞
6.3
6
*
V03AH01
ATC
diazoxide; systemic
+∞
6.3
6
*
ZXE20
NOMESCO Finland
More than three and less than five hours
2.4
6.3
48
227
D76
ICPC
Malignant neoplasm pancreas
27.5
6.3
8
*
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
8.1
6.2
13
17

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
89
218
6.18
37.20
3.0
4.8
2.86
27.32
ug/l
0.71
66
186
54
88
7.81
33.57
2.2
3.3
32.16
2076.41
u/ml
0.67
45
73
42
55
9.20
31.31
1.8
1.4
218.60
296.55
ug/g
1.19
33
33
134
621
3.96
22.38
3.7
2.6
65.06
63.02
u/l
0.08
129
576
159
841
4.21
21.55
6.9
4.8
34.69
35.32
g/l
0.76
154
798
162
881
4.18
20.77
7.8
5.8
1.22
1.21
mmol/l
0.26
154
808
63
183
4.42
20.23
2.8
2.5
260.02
32.49
u/l
0.55
55
153
166
963
3.95
18.29
10.7
6.8
1.21
1.21
mmol/l
0.18
131
820
123
605
3.34
17.42
4.8
4.0
7.41
7.40
ph
0.40
32
132
159
941
3.49
16.01
16.9
14.8
1.24
1.29
inr
0.40
62
296
50
146
4.14
15.66
4.5
3.7
89.56
79.68
ng/l
0.39
43
128
172
1142
3.32
12.83
7.7
4.8
7.09
6.81
mmol/l
0.90
166
1060
97
484
2.80
12.32
4.0
3.9
91.26
88.93
%
0.34
97
477
128
762
2.63
11.08
3.1
2.2
80.55
76.44
nmol/l
0.71
120
666
50
184
3.22
10.84
1.6
1.4
—
—
—
0
0
57
231
2.98
10.45
2.4
3.4
8.92
8.92
umol/l
0.00
49
203
60
259
2.81
9.74
6.5
6.8
106.32
103.86
mmol/l
4.77
60
259
101
575
2.40
9.12
3.2
3.1
1.42
0.49
e6/l
0.35
78
426
20
28
7.74
8.96
1.4
1.2
—
—
nmol/l
—
0
0
20
28
7.74
8.96
1.5
1.2
—
—
—
0
0
97
546
2.39
8.95
3.2
3.1
—
—
—
0
0
53
224
2.80
8.89
7.8
7.3
5.13
5.12
kpa
0.05
53
216
45
175
2.98
8.78
4.2
4.3
1.22
1.23
mmol/l
0.09
37
160
68
332
2.52
8.51
3.1
3.2
0.81
0.82
mmol/l
0.26
68
313
52
227
2.69
8.14
7.9
7.3
0.50
1.05
mmol/l
0.46
47
190
48
203
2.75
7.98
8.2
7.8
96.17
96.03
%
0.08
48
197
102
622
2.19
7.45
3.3
3.4
201.44
57.50
e6/l
0.46
77
472
14
15
9.88
7.40
1.9
1.5
—
—
—
0
0
100
612
2.16
7.17
3.8
4.0
9.92
7.81
mg/mmol
0.19
60
399
95
580
2.12
6.76
3.2
3.3
66.40
154.99
mg/l
0.38
59
387
98
608
2.10
6.66
3.3
3.2
6.89
7.66
mmol/l
1.14
84
498
54
263
2.40
6.64
1.6
1.3
—
—
—
0
0
108
708
2.03
6.20
3.9
3.9
54.90
76.79
e6/l
0.25
81
504
163
1242
2.21
6.20
4.9
4.5
—
368.13
—
0
24
39
170
2.57
6.04
4.8
4.0
—
—
—
0
0
99
634
2.02
6.03
4.4
3.4
2.39
2.35
mmol/l
1.14
93
560
24
80
3.24
6.01
4.5
4.6
—
—
—
0
0
112
752
2.00
5.94
2.4
2.2
—
—
—
0
0
79
471
2.06
5.82
8.1
7.1
—
—
—
0
0
17
46
3.92
5.76
4.9
3.3
2.80
2.24
mmol/l
0.40
11
28
131
948
1.94
5.40
4.3
3.8
0.00
0.00
estimate
0.50
40
213
122
864
1.92
5.34
15.3
10.5
0.00
0.00
e9/l
0.50
105
702
34
147
2.55
5.34
4.3
5.0
0.09
0.04
%
0.21
11
47
65
371
2.07
5.32
3.8
3.0
2.50
2.46
mmol/l
1.44
59
322
147
1113
1.97
5.21
10.0
9.2
4.50
4.22
e9/l
0.74
134
973
47
239
2.23
5.15
1.6
1.3
—
—
—
0
0
131
958
1.91
5.12
4.3
3.8
0.00
0.00
estimate
-0.00
38
189
91
592
1.92
5.09
2.8
2.4
—
—
—
0
0
82
517
1.93
5.03
1.7
1.6
1.53
1.34
mmol/l
0.87
69
420
129
945
1.88
4.95
5.8
5.2
0.00
0.00
estimate
-0.00
38
198
33
148
2.45
4.79
4.4
4.8
0.82
0.35
%
0.81
11
53
169
1361
2.04
4.79
5.2
4.1
—
—
—
0
0
124
906
1.84
4.71
7.0
6.4
—
—
—
0
0
155
1217
1.93
4.67
5.1
3.2
66.44
49.79
u/l
0.70
148
1129
169
1374
1.99
4.48
4.4
3.8
14.85
14.92
pmol/l
0.12
157
1223
55
313
2.01
4.47
2.7
3.0
1.04
2.11
e6/l
0.95
23
165
70
434
1.90
4.43
2.8
2.7
4.05
3.96
e6/l
0.04
70
396
33
154
2.34
4.39
4.5
4.9
0.09
0.17
%
0.31
11
53
74
471
1.86
4.30
1.3
1.4
—
—
—
0
0
84
558
1.82
4.25
5.2
4.3
—
—
—
0
0
8
10
8.25
4.09
3.0
1.6
—
—
—
0
0
50
284
1.98
4.06
3.0
2.5
21.70
22.69
%
0.16
43
248
206
1835
2.93
3.99
6.5
4.8
6.49
6.03
mmol/l
2.70
198
1676
33
162
2.22
3.91
6.2
8.3
—
—
—
0
0
127
968
1.74
3.89
5.9
5.6
0.64
0.59
e9/l
1.10
114
840
34
170
2.18
3.85
4.5
4.7
0.55
0.84
%
0.49
11
69
14
44
3.33
3.85
4.8
3.3
—
—
—
0
0
127
970
1.73
3.84
5.9
5.6
0.04
0.04
e9/l
0.64
114
842
42
230
2.02
3.76
1.4
1.6
—
—
—
0
0
200
1768
2.44
3.73
8.9
6.1
42.12
40.46
mmol/mol
1.36
194
1644
9
16
5.81
3.70
1.0
1.3
—
—
—
0
0
84
578
1.73
3.66
2.0
2.1
185.64
219.02
u/l
0.22
77
542
207
1862
2.89
3.66
24.3
15.3
32.55
23.49
mg/l
2.29
194
1488
73
484
1.76
3.62
1.5
1.5
21.79
21.61
nmol/l
0.04
66
404
127
983
1.69
3.55
6.0
5.7
1.88
1.88
e9/l
0.00
116
878
71
470
1.75
3.53
2.5
2.0
3.34
3.15
mg/l
0.20
66
407
128
995
1.68
3.50
6.0
5.8
0.20
0.19
e9/l
0.29
116
881
156
1296
1.70
3.16
4.9
4.2
—
—
—
0
0
12
35
3.57
3.16
2.3
2.1
—
—
—
0
0
23
106
2.31
3.16
12.0
9.2
—
—
—
0
0
105
793
1.62
3.09
4.4
3.9
39.52
45.62
ng/l
0.19
79
595
192
1700
2.02
3.07
5.3
4.6
1.91
1.94
mu/l
0.13
178
1525
33
179
1.99
3.03
2.8
2.8
60.67
71.72
e9/l
1.19
26
137
26
129
2.15
3.01
11.4
6.7
24.85
24.72
mmol/l
0.08
26
123
210
1931
2.93
3.00
31.3
17.7
139.67
139.65
mmol/l
0.04
210
1884
5
5
10.19
2.99
3.6
3.8
—
—
—
0
0
210
1932
2.91
2.98
31.2
17.9
3.96
3.99
mmol/l
0.86
210
1885
75
528
1.64
2.89
4.1
3.5
—
—
—
0
0
6
9
6.81
2.88
2.7
1.4
26.67
30.22
umol/l
—
6
9
38
221
1.87
2.85
1.5
1.3
—
—
—
0
0
27
139
2.07
2.85
8.4
4.3
—
—
—
0
0
10
28
3.69
2.82
3.1
3.9
—
—
—
0
0
74
522
1.63
2.82
2.5
3.0
388.58
8302.61
umol/l
2.59
59
447
47
294
1.76
2.79
2.3
1.9
—
—
—
0
0
5
6
8.49
2.76
2.0
1.5
167.00
63.67
nmol/24h
—
5
6
18
80
2.36
2.69
2.7
3.1
—
—
—
0
0
74
529
1.60
2.65
4.8
4.0
0.00
0.00
estimate
-0.00
34
192
211
1978
2.63
2.61
30.9
18.2
85.27
80.30
umol/l
0.79
211
1978
12
42
2.96
2.59
4.6
3.1
52.50
60.26
%
0.95
12
42
9
27
3.43
2.42
3.7
1.6
14.83
15.64
ug/l
—
9
27
77
568
1.55
2.37
3.6
3.2
—
—
—
0
0
99
772
1.51
2.35
3.3
2.7
162.47
138.89
ug/l
0.32
92
707
54
367
1.62
2.35
2.4
1.7
1281.71
1237.04
nmol/l
0.12
45
281
162
1404
1.58
2.33
4.8
4.2
13.29
12.49
mm/h
0.28
148
1280
101
792
1.51
2.33
2.2
1.9
91.01
95.66
pmol/l
0.51
58
416
8
23
3.57
2.29
1.1
1.2
—
—
—
0
0
11
41
2.77
2.24
3.6
2.6
3.52
4.81
e9/l
1.44
11
41
53
363
1.61
2.23
5.4
3.9
281.41
135.28
ng/l
0.51
44
293
59
416
1.57
2.19
1.6
1.8
2.26
1.41
mg/l
0.56
45
326
6
14
4.37
2.16
1.5
1.3
—
—
—
0
0
18
89
2.11
2.12
2.4
1.9
8.81
5.16
ug/l
0.24
18
83
60
430
1.54
2.07
2.1
1.7
449.57
447.11
pmol/l
0.03
47
350
61
439
1.54
2.07
4.0
3.7
—
—
—
0
0
11
44
2.58
2.04
4.9
2.5
—
—
—
0
0
208
1948
2.24
2.04
24.5
14.5
—
—
—
0
0
21
114
1.93
1.95
1.3
1.2
—
—
—
0
0
30
184
1.73
1.91
1.6
1.5
—
—
—
0
0
55
397
1.51
1.82
1.3
1.2
0.93
0.95
u/ml
0.02
13
111
14
68
2.13
1.74
1.9
5.0
40.40
148.20
mg/l
—
8
53
14
68
2.13
1.74
1.9
5.0
33.19
28.20
mg/l
—
8
53
10
41
2.51
1.66
1.3
2.0
—
—
—
0
0
49
355
1.49
1.59
1.4
1.5
2.48
2.72
g/l
0.40
30
215
18
100
1.87
1.58
1.1
1.2
—
—
—
0
0
12
59
2.09
1.46
1.3
1.1
—
—
—
0
0
7
28
2.55
1.46
1.1
1.1
—
—
—
0
0
75
598
1.39
1.45
4.7
4.1
—
—
—
0
0
6
22
2.77
1.44
1.0
1.1
—
—
—
0
0
35
244
1.52
1.37
1.3
1.3
480.00
556.36
titre
—
7
55
10
49
2.09
1.24
1.3
1.3
—
3.19
—
0
8
8
37
2.21
1.23
2.0
3.1
—
—
—
0
0
13
71
1.88
1.22
1.8
1.7
—
—
—
0
0
10
50
2.05
1.18
2.0
5.7
—
—
—
0
0
7
31
2.30
1.11
2.0
2.0
—
—
—
0
0
7
32
2.23
1.09
1.9
2.0
31.14
33.09
pg
—
7
32
22
146
1.56
1.08
1.5
2.7
—
—
—
0
0
16
101
1.63
0.96
2.6
2.6
—
—
—
0
0
12
70
1.76
0.94
1.9
2.6
40.39
38.11
g/l
1.09
12
65
25
179
1.45
0.89
1.4
1.4
—
—
—
0
0
10
57
1.79
0.85
1.6
1.5
—
—
—
0
0
0
27
0.00
0.78
0.0
1.1
—
—
—
0
0
19
133
1.47
0.76
1.2
1.3
—
—
—
0
0
5
25
2.02
0.73
1.0
1.0
—
—
—
0
0
211
2057
1.63
0.72
38.4
22.3
4.38
4.50
e12/l
2.69
211
1997
211
2057
1.63
0.72
38.3
22.3
6.94
6.69
e9/l
0.99
211
1999
211
2057
1.63
0.72
38.8
22.3
39.36
40.33
%
1.53
197
1949
211
2057
1.63
0.72
38.7
22.4
131.56
136.01
g/l
3.85
211
2026
211
2056
1.64
0.72
38.3
22.2
91.43
91.33
fl
0.11
211
2027
211
2056
1.64
0.72
38.3
22.2
30.26
30.42
pg
0.70
211
2026
211
2055
1.65
0.72
38.4
22.3
247.13
242.13
e9/l
0.46
211
2006
7
41
1.73
0.70
4.0
2.8
—
—
—
0
0
13
87
1.53
0.65
13.4
4.6
1.64
1.55
%
0.23
13
82
24
182
1.36
0.64
3.7
3.9
2.37
2.11
mmol/l
0.13
19
144
5
29
1.74
0.64
3.0
3.3
108.00
106.07
mmol/l
—
5
29
5
29
1.74
0.64
1.8
2.4
93.64
89.01
%
—
5
29
5
29
1.74
0.64
1.4
1.1
—
—
—
0
0
5
29
1.74
0.64
3.0
3.3
4.08
3.99
mmol/l
—
5
29
5
29
1.74
0.64
3.0
3.3
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
160.63
—
0
20
0
20
0.00
0.60
0.0
1.1
—
0.21
—
0
12
0
21
0.00
0.60
0.0
2.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
6
36
1.68
0.57
2.2
3.2
10.67
37.14
u/ml
—
6
36
19
142
1.37
0.56
1.4
1.4
—
—
—
0
0
14
100
1.43
0.53
4.6
4.3
—
—
—
0
0
28
227
1.27
0.49
1.3
1.4
—
—
—
0
0
7
45
1.57
0.49
2.4
2.2
—
—
—
0
0
21
166
1.29
0.45
4.0
3.7
—
—
—
0
0
7
51
1.38
0.44
1.1
1.5
—
—
—
0
0
88
807
1.15
0.43
6.1
5.2
2.25
2.68
ug/l
0.38
80
725
8
56
1.44
0.43
1.1
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
3.4
—
44.60
—
0
10
0
16
0.00
0.41
0.0
1.1
—
0.79
—
0
9
0
16
0.00
0.41
0.0
1.1
—
2.01
—
0
7
47
412
1.18
0.41
4.6
4.1
1.02
1.02
kg/l
—
9
46
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
31.08
—
0
13
189
1838
1.20
0.38
5.2
4.7
1.34
1.45
mmol/l
2.83
180
1679
190
1851
1.19
0.35
5.4
4.7
4.27
4.56
mmol/l
3.18
181
1702
53
480
1.14
0.31
3.8
3.2
0.85
0.78
ug/l
0.28
44
324
25
290
0.84
0.29
1.0
1.3
1.25
8.57
u/ml
1.90
14
111
10
76
1.33
0.28
4.5
2.0
379.60
337.54
ug/l
—
10
70
9
74
1.23
0.25
1.1
1.6
—
—
—
0
0
62
667
0.90
0.25
3.5
3.2
—
—
—
0
0
12
96
1.26
0.25
2.8
2.7
0.74
0.68
%
0.28
12
96
15
124
1.23
0.24
2.9
2.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
149.70
—
0
10
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
182
1784
1.12
0.21
4.7
4.2
1.43
1.27
mmol/l
1.75
170
1626
0
13
0.00
0.21
0.0
1.2
—
1.74
—
0
13
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
9
111
0.80
0.20
2.0
2.2
4.21
6.77
e9/l
—
9
87
192
1889
1.13
0.20
6.0
5.3
2.48
2.69
mmol/l
2.56
182
1732
7
59
1.19
0.18
7.1
5.6
—
—
—
0
0
7
59
1.19
0.18
1.0
1.2
—
—
—
0
0
11
131
0.83
0.17
1.1
1.4
—
—
—
0
0
10
82
1.23
0.17
1.5
1.3
—
—
—
0
0
8
71
1.13
0.16
1.0
1.1
—
—
—
0
0
10
119
0.83
0.16
1.7
1.6
—
—
—
0
0
13
149
0.86
0.14
1.4
1.4
—
—
—
0
0
19
172
1.11
0.12
11.3
4.4
—
—
—
0
0
11
126
0.87
0.11
1.2
1.4
—
—
—
0
0
12
107
1.13
0.08
1.2
1.2
88.86
157.03
u/ml
0.56
12
96
21
203
1.04
0.01
2.2
1.4
—
—
—
0
0
23
236
0.97
0.00
2.1
1.5
—
—
—
0
0
28
274
1.03
0.00
2.1
1.7
—
—
—
0
0
31
309
1.00
0.00
1.1
1.3
10.14
30.93
iu/ml
—
7
113
5
52
0.96
0.00
1.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
9
92
0.98
-0.00
10.1
3.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
-0.00
1.8
3.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
1.15
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1.00
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
95
0.95
-0.00
1.3
2.1
1.69
1.51
g/l
—
9
79
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_ENDOCRINE_PANCREAS and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_ENDOCRINE_PANCREAS 2.501 [1.71, 3.67] < 0.001
Birth year 0.991 [0.98, 1.0] 0.048

During the follow-up period (1.1.1998 — 31.12.2019), 88 out of 343 females with CD2_BENIGN_ENDOCRINE_PANCREAS died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_ENDOCRINE_PANCREAS 2.53 [1.48, 4.32] < 0.001
Birth year 0.985 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 73 out of 275 males with CD2_BENIGN_ENDOCRINE_PANCREAS died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_ENDOCRINE_PANCREAS.

N-year risk Females Males
1 0.26% 0.423%
5 1.356% 2.896%
10 3.129% 6.819%
15 6.062% 13.219%
20 10.476% 20.537%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_ENDOCRINE_PANCREAS – Benign neoplasm: Endocrine pancreas

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data