No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1238 |
4. Check minimum number of eventsNone |
1238 |
5. Include endpointsNone |
1238 |
6. Filter based on genotype QC (FinnGen only) |
1209 |
Control definitions (FinnGen only)
- Control exclude
- I9_CEREBVASC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I60-I69
- Name in latin
- Alia haemorrhagia intracranialis non traumatica
Similar endpoints
↥List of similar endpoints to
Other intracranial haemorrhages
based on the number of shared cases.
Similar with more cases:
- Cerebrovascular diseases
- Bleeding
- STROKE
- Neurological diseases, wide definition
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10757 | 4015 | 6617 |
| Only index persons | 8357 | 3132 | 5225 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.12 | 0.18 |
| Only index persons | 0.17 | 0.12 | 0.20 |
| Median age at first event (years) | |||
| Whole population | 74.17 | 76.06 | 73.01 |
| Only index persons | 73.90 | 75.44 | 72.98 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1209 | 375 | 834 |
| Unadjusted period prevalence (%) | 0.30 | 0.13 | 0.38 |
| Median age at first event (years) | 72.76 | 69.60 | 74.17 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1238
- Matched controls
- 12380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
150.4
307.7
252
21
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
4503599627370496.0
307.7
951
*
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
62.2
307.7
632
204
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
145.4
307.7
528
63
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
60.2
296.8
167
32
AA1AD
NOMESCO Finland
CT of head and brain
7.6
284.0
764
2166
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
+∞
275.6
254
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
20.9
141.3
109
57
I62.1
ICD-10 Finland
Nontraumatic extradural haemorrhage
+∞
140.3
132
*
K90
ICPC
Stroke/cerebrovascular accident
28.0
140.3
96
37
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
52.0
135.3
78
16
N03AX14
ATC
levetiracetam; systemic
12.2
106.7
110
98
W19
ICD-10 Finland
Unspecified fall
4.8
103.7
275
690
X59
ICD-10 Finland
Exposure to unspecified factor
4.0
101.8
388
1276
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
96.1
91
*
ZXD05
NOMESCO Finland
Urgent procedure
3.4
96.1
576
2524
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.2
88.1
610
2876
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
32.5
77.1
50
16
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
9.9
76.3
90
97
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
+∞
75.8
72
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
265.8
74.2
75
*
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
717.1
69.8
68
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
6.0
66.9
125
227
G91.0
ICD-10 Finland
Communicating hydrocephalus
30.4
66.4
44
15
K91
ICPC
Cerebrovascular disease
26.5
66.3
46
18
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
+∞
64.1
61
*
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
+∞
55.6
53
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
55.2
378
1688
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
50.4
48
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
260.3
49.4
50
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
177.1
49.2
51
*
R51.80
ICD-10 Finland
Headache
3.3
47.9
204
693
T90.5
ICD-10 Finland
Sequelae of intracranial injury
13.3
47.0
45
35
ZXD35
NOMESCO Finland
Usual procedure
5.7
46.4
89
165
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
+∞
43.0
41
*
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
11.7
42.4
44
39
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.8
42.3
137
388
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
14.6
40.9
37
26
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.6
40.0
277
1221
XA800
NOMESCO Finland
Neuropsychological investigation
7.0
39.8
62
93
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
4.4
39.2
102
245
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
106.0
37.9
41
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.4
37.8
148
474
B01AA03
ATC
warfarin; systemic
2.3
37.8
422
2300
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
5.8
37.5
70
126
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.8
37.1
122
348
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
7.6
37.1
53
72
N18
ICPC
Paralysis/weakness
9.9
37.0
43
45
R41.0
ICD-10 Finland
Disorientation, unspecified
4.5
36.4
92
216
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
7.4
35.4
52
73
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.3
34.8
140
456
AAD12
NOMESCO Finland
Drainage of subdural fluid
67.0
34.2
39
6
AA1AA
NOMESCO Finland
Head X-ray examination
10.0
34.0
39
40
R42
ICD-10 Finland
Dizziness and giddiness
2.2
31.0
346
1861
PA6AD
NOMESCO Finland
CT of neck arteries
6.5
31.0
51
81
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.9
30.7
70
151
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
+∞
30.3
29
*
AAF00
NOMESCO Finland
Ventriculostomy
33.5
30.1
39
12
N03AB02
ATC
phenytoin; systemic
8.5
30.1
39
47
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
29.8
287
1451
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
29.3
28
*
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
+∞
29.3
28
*
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
56.4
28.3
33
6
N03AF02
ATC
oxcarbazepine; oral
5.1
28.1
60
122
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.1
27.9
49
83
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
5.0
26.9
59
123
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.5
26.7
98
300
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.9
25.8
441
2741
R4120
NOMESCO Finland
Occupational therapy
3.7
25.7
85
243
S06.3
ICD-10 Finland
Focal brain injury
7.0
25.6
39
57
Y96.9
ICD-10 Finland
Unspecified type of accident
6.0
25.4
45
77
WX002
NOMESCO Finland
Sedation and analgesia
2.1
24.8
288
1555
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
92.0
24.7
27
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.6
24.2
84
248
PA2AD
NOMESCO Finland
CT angiography of brain
30.7
22.8
30
10
N80
ICPC
Head injury other
5.3
22.5
46
90
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
+∞
21.9
21
*
N02BE01
ATC
paracetamol; systemic, rectal
2.2
21.4
1064
9080
R53
ICD-10 Finland
Malaise and fatigue
2.0
21.1
309
1803
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
20.9
20
*
S06.0
ICD-10 Finland
Concussion
2.5
20.7
146
637
Z2445
NOMESCO Finland
Psychologist
5.4
19.8
39
74
N05AH04
ATC
quetiapine; oral
2.2
19.6
193
972
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
31.9
19.3
25
8
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.8
19.3
44
95
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
7.6
19.1
27
36
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
19.0
834
6667
N19
ICPC
Speech disorder
6.9
18.7
29
43
H53.4
ICD-10 Finland
Visual field defects
5.5
18.6
36
67
N03AG01
ATC
valproic acid; systemic, rectal
3.2
18.5
77
255
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
15.9
17.5
28
18
C07AB07
ATC
bisoprolol; oral
1.7
17.4
705
5450
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
16.7
740
5828
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
91.3
16.6
18
*
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
172.2
16.5
17
*
SPAT1216
SPAT
Assessment of functional ability
1.9
16.5
250
1463
N29
ICPC
Neurological sympt/complt other
4.6
16.2
38
84
L28
ICPC
Limited function/disability (L)
1.8
16.0
273
1657
SPAT1234
SPAT
Support of social functional capacity
2.6
15.8
98
402
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
15.7
235
1366
I63.8
ICD-10 Finland
Other cerebral infarction
+∞
15.7
15
*
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
+∞
15.7
15
*
PA7BD
NOMESCO Finland
CT angiography of neck and brain
5.7
15.6
29
52
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
162.0
15.5
16
*
Z3231
NOMESCO Finland
Registered nurse
1.7
15.4
344
2255
F05.9
ICD-10 Finland
Delirium, unspecified
3.8
15.3
46
123
G91.1
ICD-10 Finland
Obstructive hydrocephalus
23.7
15.1
21
9
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
15.0
233
1369
D68.3
ICD-10 Finland
Haemorrhagic disorder due to circulating anticoagulants
15.3
14.9
24
16
R47.0
ICD-10 Finland
Dysphasia and aphasia
12.6
14.9
26
21
N28
ICPC
Limited function/disability (N)
4.6
14.8
35
78
SPAT1215
SPAT
Assessment of need for medical rehabilitation
3.1
14.5
60
198
N06AX11
ATC
mirtazapine; oral
1.7
14.5
376
2559
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.3
14.4
54
168
SPAT1229
SPAT
Assessment of need for aid
2.2
14.2
128
619
X58
ICD-10 Finland
Exposure to other specified factors
2.0
13.8
151
787
SPAT1053
SPAT
Memory test
1.8
13.8
265
1659
WX882
NOMESCO Finland
High dependency care
3.4
13.7
49
148
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.0
13.6
148
770
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
34.4
13.5
17
5
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
141.5
13.5
14
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.5
13.4
84
346
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
18.5
13.4
20
11
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.9
13.2
61
215
N05AX08
ATC
risperidone; systemic
2.1
13.1
127
632
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
13.0
593
4589
P20
ICPC
Memory disturbance
1.8
13.0
241
1490
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
28.7
13.0
17
6
R55
ICD-10 Finland
Syncope and collapse
1.9
12.8
169
939
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.9
12.8
180
1022
FFW96
NOMESCO Finland
Other operation on atria
70.6
12.6
14
*
N05CF01
ATC
zopiclone; oral
1.6
12.3
413
2971
R4150
NOMESCO Finland
Neuropsychological rehabilitation
37.9
12.2
15
*
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
11.9
347
2410
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
11.9
219
1348
K78
ICPC
Atrial fibrillation/flutter
2.0
11.5
140
756
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
+∞
11.5
11
*
B01AC04
ATC
clopidogrel; oral
1.7
11.5
231
1458
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.5
11.5
39
114
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.2
11.4
30
73
SPAT1254
SPAT
Administration of medicine
1.8
11.3
205
1255
A28
ICPC
Limited function/disability NOS
1.7
11.3
271
1791
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
5.2
11.3
23
45
WX892
NOMESCO Finland
Monitored bed care
2.1
11.2
104
508
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
11.0
423
3123
R1250
NOMESCO Finland
Evaluation of functional capability
3.8
10.9
33
89
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
10.9
191
1159
ZXE00
NOMESCO Finland
One hour or less
1.5
10.8
435
3239
B01AB05
ATC
enoxaparin; parenteral
1.6
10.8
383
2774
G41.9
ICD-10 Finland
Status epilepticus, unspecified
9.7
10.8
21
22
ZXA05
NOMESCO Finland
Left side
1.6
10.7
322
2246
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.2
10.6
86
399
C03CA01
ATC
furosemide; systemic
1.5
10.5
508
3927
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.1
10.5
104
522
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
+∞
10.4
10
*
ABB40
NOMESCO Finland
Evacuation of spontaneous haematoma of spinal canal
+∞
10.4
10
*
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
+∞
10.4
10
*
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
7.8
10.4
23
30
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.4
10.4
73
318
J01DB01
ATC
cefalexin; oral
1.5
10.3
901
7842
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
23.6
10.2
14
6
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.2
491
3786
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
13.2
10.2
17
13
B01AC07
ATC
dipyridamole; systemic
2.3
10.2
80
366
TKC20
NOMESCO Finland
Catheterisation of bladder
2.0
10.0
113
594
R50.9
ICD-10 Finland
Fever, unspecified
1.7
10.0
186
1146
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
9.9
395
2924
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
4.5
9.6
23
52
N03AX18
ATC
lacosamide; systemic
11.5
9.6
17
15
F03
ICD-10 Finland
Unspecified dementia
2.1
9.4
85
411
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.3
9.4
24
57
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
9.4
9
*
I62
ICD-10 Finland
Other nontraumatic intracranial haemorrhage
+∞
9.4
9
*
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
+∞
9.4
9
*
I61.6
ICD-10 Finland
Intracerebral haemorrhage, multiple localized
+∞
9.4
9
*
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
+∞
9.4
9
*
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
+∞
9.4
9
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
9.4
350
2551
S06.9
ICD-10 Finland
Intracranial injury, unspecified
7.0
9.3
22
32
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
9.3
89
441
X57
ICD-10 Finland
Unspecified privation
3.4
9.2
33
100
N03AF01
ATC
carbamazepine; oral, rectal
2.3
9.1
69
311
C09AA02
ATC
enalapril; systemic
1.6
9.1
286
2007
SPAT1153
SPAT
Removal of sutures
1.5
9.1
394
2960
N99
ICPC
Neurological disease other
4.2
8.9
23
55
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
8.9
259
1784
SPAT1301
SPAT
No procedures
1.5
8.9
379
2833
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
8.8
162
993
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
10.8
8.8
16
15
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
8.7
72
336
C10AA01
ATC
simvastatin; oral
1.4
8.7
589
4801
SPAT1360
SPAT
Extensive global examination
2.0
8.7
92
473
AAD15
NOMESCO Finland
Evacuation of traumatic intracerebral haematoma
50.3
8.7
10
*
N05BA04
ATC
oxazepam; oral
1.5
8.6
280
1976
G40.10
ICD-10 Finland
Simple partial seizures
8.3
8.6
18
22
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
16.4
8.6
13
8
Y94.0
ICD-10 Finland
Accident at home
3.5
8.5
29
85
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
27.7
8.5
11
*
R11
ICD-10 Finland
Nausea and vomiting
2.0
8.5
98
520
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
8.5
95
499
S18
ICPC
Laceration/cut
1.4
8.4
532
4276
WX872
NOMESCO Finland
Intensive care
2.2
8.4
71
335
SPAT1252
SPAT
Overall medication plan or its review
1.9
8.4
104
565
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
8.3
185
1192
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
+∞
8.3
8
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.1
8.2
79
392
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.1
8.1
79
394
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
33.6
8.1
10
*
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
17.3
8.1
12
7
E86
ICD-10 Finland
Volume depletion
2.6
8.1
45
176
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.6
8.0
45
177
N30.0
ICD-10 Finland
Acute cystitis
1.7
7.9
152
942
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.9
283
2034
AA5PD
NOMESCO Finland
CT examination of brain pefusion
10.9
7.8
14
13
C08CA01
ATC
amlodipine; oral
1.4
7.8
488
3901
205
Kela drug reimbursment
Chronic hypertension
1.4
7.7
403
3117
R4110
NOMESCO Finland
Physiotherapy
1.5
7.7
290
2107
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
7.7
59
268
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
7.7
149
927
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
7.6
89
474
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.7
7.6
129
772
XX2BT
NOMESCO Finland
Other injection with X-ray guidance
18.5
7.6
11
6
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
18.5
7.6
11
6
S06.4
ICD-10 Finland
Epidural haemorrhage
25.2
7.6
10
*
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.2
7.6
29
92
K99
ICPC
Cardiovascular disease other
2.5
7.6
46
188
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
7.6
106
600
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
3.8
7.5
22
58
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
10.1
7.5
14
14
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.2
7.5
63
297
G81.9
ICD-10 Finland
Hemiplegia, unspecified
7.2
7.5
17
24
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
7.5
75
379
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
80.6
7.4
8
*
G72.8
ICD-10 Finland
Other specified myopathies
3.0
7.4
31
104
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
7.3
243
1718
SPAT1263
SPAT
Sampling
1.4
7.3
449
3567
PA5HT
NOMESCO Finland
Embolisation of extensive arterio-venous malformation of carotis externa area
+∞
7.3
7
*
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
+∞
7.3
7
*
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
+∞
7.3
7
*
TFP20
NOMESCO Finland
Cardiodefibrillation
1.8
7.1
109
635
A02BC02
ATC
pantoprazole; systemic
1.4
7.1
751
6518
N88
ICPC
Epilepsy
8.8
7.1
14
16
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.1
7.0
28
91
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.7
7.0
141
886
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
4.4
7.0
17
39
S01.0
ICD-10 Finland
Open wound of scalp
1.8
6.9
104
601
WYA20
NOMESCO Finland
Home visit
2.8
6.9
33
119
N01
ICPC
Headache
2.0
6.9
75
391
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
6.8
58
275
G44.2
ICD-10 Finland
Tension-type headache
1.8
6.8
106
620
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
6.8
323
2447
F10.24
ICD-10 Finland
Alcohol depence active use
4.3
6.8
17
40
R51
ICD-10 Finland
Headache
2.4
6.7
43
180
Z43.0
ICD-10 Finland
Attention to tracheostomy
16.8
6.7
10
6
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
6.7
343
2629
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
22.6
6.7
9
*
SPAT1167
SPAT
Insertion of urinary catheter
2.2
6.7
57
271
C10AA05
ATC
atorvastatin; oral
1.4
6.7
485
3948
R4130
NOMESCO Finland
Speech therapy
3.1
6.6
26
84
WX704
NOMESCO Finland
Intubation
1.9
6.6
81
440
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.1
6.6
59
286
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.6
6.5
35
135
S06.2
ICD-10 Finland
Diffuse brain injury
5.4
6.5
18
34
G30.8
ICD-10 Finland
Other Alzheimer disease
2.3
6.5
47
209
G04CA02
ATC
tamsulosin; oral
1.4
6.5
430
3446
WW500
NOMESCO Finland
Blood transfusion
2.1
6.4
57
275
R06AE07
ATC
cetirizine; oral
1.4
6.4
373
2922
F80.1
ICD-10 Finland
Expressive language disorder
7.4
6.4
14
19
XX3XW, ,
NOMESCO Finland
7.4
6.4
14
19
C09AA05
ATC
ramipril; oral
1.4
6.4
337
2596
F05.1
ICD-10 Finland
Delirium superimposed on dementia
4.1
6.4
17
42
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.8
6.4
91
519
ZXD00
NOMESCO Finland
Emergency procedure
2.4
6.3
41
173
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.7
6.3
113
687
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
1.9
6.3
75
403
G41.0
ICD-10 Finland
Grand mal status epilepticus
18.1
6.3
9
5
S00.0
ICD-10 Finland
Superficial injury of scalp
2.7
6.3
33
126
A04
ICPC
Weakness/tiredness general
1.6
6.3
165
1107
C08CA06
ATC
nimodipine; systemic
+∞
6.3
6
*
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
+∞
6.3
6
*
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
+∞
6.3
6
*
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
+∞
6.3
6
*
PA2PT
NOMESCO Finland
Permanent closure of brain artery
+∞
6.3
6
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
6.3
181
1240
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
6.2
91
522
S06.8
ICD-10 Finland
Other intracranial injuries
26.8
6.2
8
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
6.2
50
232
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
6.2
83
464
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.1
405
3235
N05BA06
ATC
lorazepam; systemic, sublingual
2.0
6.1
68
357
XCK00
NOMESCO Finland
Perimetry
1.9
6.1
76
415
N05CD07
ATC
temazepam; oral
1.6
6.1
167
1131
AAF15
NOMESCO Finland
Ventriculoatrial shunt
8.6
6.1
12
14
XA400
NOMESCO Finland
EEG
8.6
6.1
12
14
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
3.6
6.0
19
53
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
372
1393
3.39
77.55
2.5
2.0
30.49
30.17
s
0.33
362
1342
542
2734
2.75
64.04
2.9
2.0
264.90
287.29
u/l
0.13
526
2530
769
5098
2.34
44.75
25.7
19.7
1.40
1.40
inr
0.01
245
1464
836
5805
2.36
42.72
7.6
4.8
6.90
6.89
mmol/l
0.06
810
5477
78
152
5.41
38.43
2.2
1.4
27249.51
309.46
e6/l
0.53
68
123
78
152
5.41
38.43
2.2
1.3
41.97
64.60
e6/l
0.19
64
119
55
75
7.63
38.39
2.1
1.2
—
—
—
0
0
666
4377
2.13
36.68
3.5
2.7
—
—
—
0
0
312
1572
2.32
33.01
3.2
3.0
0.82
0.82
mmol/l
0.08
299
1454
409
2334
2.12
31.55
3.3
2.4
—
—
—
0
0
37
42
9.05
29.92
1.8
2.1
—
—
—
0
0
608
4076
1.97
29.38
5.0
4.1
70.39
68.03
ng/l
0.02
519
3164
257
1279
2.27
27.48
8.6
6.7
1.07
1.27
mmol/l
0.32
202
987
254
1276
2.25
26.46
8.7
6.7
4.95
5.09
kpa
1.87
243
1206
252
1275
2.23
25.74
8.8
6.7
13.31
11.63
kpa
4.23
241
1205
376
2227
1.99
25.19
5.7
4.0
80.95
83.52
%
1.15
371
2168
696
5088
1.84
23.85
9.3
7.0
1.20
1.21
mmol/l
1.84
604
4292
208
1043
2.20
21.43
9.6
7.4
117.31
120.28
g/l
1.28
203
1007
29
37
8.00
21.34
1.9
1.2
—
—
—
0
0
223
1162
2.12
20.79
9.2
6.9
96.74
95.12
%
7.26
218
1113
197
979
2.20
20.71
7.1
6.7
10.02
11.61
mmol/l
2.09
191
926
247
1352
2.03
20.12
5.4
5.5
1.01
1.04
mmol/l
0.81
234
1246
150
678
2.38
19.69
9.8
8.4
1.35
1.35
%
0.00
150
673
625
4611
1.72
19.04
8.7
6.1
1.20
1.21
mmol/l
3.48
572
4151
671
5103
1.69
17.79
8.0
6.2
12.54
12.66
umol/l
0.08
628
4838
791
6347
1.68
16.54
5.9
4.8
1624.05
2067.46
e6/l
0.15
19
116
66
225
3.04
15.08
3.3
2.3
3.76
3.59
g/l
0.33
61
211
146
729
2.14
14.97
10.4
6.1
24.76
24.39
mmol/l
0.55
140
690
291
1886
1.71
13.30
1.9
1.9
—
—
—
0
0
115
564
2.15
12.31
9.4
9.0
23.89
24.50
mmol/l
1.30
110
541
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
87
388
2.34
11.71
3.4
2.4
0.34
0.32
u/ml
0.31
46
208
329
2274
1.61
11.48
2.0
1.8
1184.85
1184.95
nmol/l
0.00
257
1678
166
958
1.85
11.16
8.9
6.7
1.35
1.40
mmol/l
0.36
160
933
562
4403
1.51
11.04
5.6
4.7
33.72
34.59
g/l
3.12
526
4052
494
3775
1.51
10.90
3.7
3.4
—
—
—
0
0
137
750
1.93
10.82
4.1
4.3
5.15
5.18
kpa
0.15
131
711
295
2015
1.61
10.71
4.6
4.1
141.26
350.92
ng/l
3.44
251
1750
411
3034
1.53
10.60
3.0
2.5
58.72
86.59
u/l
0.53
383
2787
179
1080
1.77
10.36
5.5
3.5
1.42
2.05
mmol/l
1.18
145
873
154
888
1.84
10.36
4.9
3.1
4.75
4.45
kpa
0.78
149
861
25
57
4.46
10.29
1.7
1.3
1.10
1.00
promille
0.10
20
39
178
1080
1.76
10.09
5.5
3.5
5.70
5.81
kpa
0.73
172
1046
203
1289
1.69
9.75
1.7
1.8
—
—
—
0
0
846
7327
1.49
9.35
10.1
7.6
84.48
81.15
u/l
0.96
795
6840
119
659
1.89
9.07
1.6
1.5
—
—
—
0
0
125
708
1.85
8.88
4.1
4.2
1.40
2.11
mmol/l
1.06
88
535
634
5232
1.43
8.79
10.8
8.7
4.40
4.34
e9/l
0.23
558
4529
132
763
1.82
8.79
1.7
1.6
—
—
—
0
0
326
2376
1.51
8.62
1.7
1.8
416.99
10805620.11
pmol/l
1.04
262
1925
524
4203
1.43
8.36
7.1
5.6
59.02
58.52
%
0.36
490
3916
16
17
9.52
8.28
1.1
1.1
90.80
87.67
%
—
5
12
989
8926
1.54
8.28
26.5
16.8
26.71
28.37
mg/l
0.93
889
7252
364
2743
1.46
8.07
3.5
3.1
33.76
34.92
u/l
0.23
345
2598
196
1292
1.61
8.06
1.8
1.8
—
—
—
0
0
370
2805
1.46
7.92
2.3
2.2
3.46
3.11
mg/l
1.30
313
2357
123
722
1.78
7.78
5.0
3.3
125.89
127.17
g/l
0.23
118
707
527
4285
1.40
7.55
7.5
5.8
25.30
26.00
%
0.70
490
3991
427
3349
1.42
7.52
3.4
3.4
2.34
2.35
mmol/l
0.12
373
2873
468
3751
1.40
7.21
3.0
2.8
186.98
162.05
ug/l
0.96
422
3377
94
522
1.87
7.13
2.1
1.8
3.18
2.54
ug/l
0.16
75
462
349
2662
1.43
7.11
1.8
1.6
18.93
19.78
nmol/l
0.40
303
2234
615
5180
1.37
6.90
4.1
3.1
71.90
56.82
u/l
1.43
565
4672
165
1086
1.60
6.79
3.3
2.6
66.13
67.87
e9/l
0.30
135
860
301
2251
1.45
6.78
3.2
2.6
3.57
4.13
e6/l
0.57
277
2037
195
1335
1.55
6.77
5.9
4.0
245.27
244.44
u/l
0.03
184
1251
444
3561
1.38
6.69
4.0
3.2
1815.44
1929.82
ng/l
0.27
402
3105
403
3192
1.39
6.51
4.0
3.4
66.39
88.76
e6/l
0.34
341
2548
204
1423
1.52
6.49
3.0
2.4
1.75
1.79
%
0.24
181
1246
96
556
1.79
6.37
4.9
2.8
1.48
1.18
%
1.53
96
551
155
1022
1.59
6.33
2.8
2.6
4.05
6.16
ug/l
3.34
136
883
441
3569
1.37
6.17
4.6
3.8
148.99
124.95
e6/l
0.11
355
2697
16
39
4.14
6.10
1.0
1.1
—
—
—
0
0
254
1880
1.44
5.97
2.9
1.6
2.20
1.51
mg/l
1.24
206
1483
22
70
3.18
5.76
1.6
1.2
2.88
1.57
u/ml
0.54
17
21
19
55
3.49
5.74
2.6
2.1
—
—
—
0
0
220
1596
1.46
5.74
2.8
2.5
2.19
2.25
g/l
0.73
200
1466
57
295
1.98
5.38
2.8
3.0
0.94
0.84
nmol/l
0.53
37
218
90
544
1.71
5.18
5.2
2.7
0.69
0.64
%
0.81
90
538
78
454
1.77
5.13
2.1
1.8
—
—
—
0
0
233
1743
1.41
5.11
2.9
2.5
12.28
12.10
umol/l
0.13
213
1601
43
205
2.14
5.06
1.4
1.6
—
—
—
0
0
1015
9453
1.41
5.05
31.3
20.3
139.43
139.60
mmol/l
1.18
997
9174
320
2531
1.36
5.00
5.2
4.2
0.00
0.00
estimate
0.50
92
816
1016
9471
1.41
4.97
31.0
20.4
4.01
4.02
mmol/l
0.13
997
9184
514
4357
1.31
4.96
2.4
2.1
88.18
92.10
pmol/l
1.23
316
2338
529
4511
1.30
4.85
5.0
3.9
0.03
0.00
estimate
0.45
103
936
206
1525
1.42
4.78
2.9
2.5
21.96
21.97
%
0.01
176
1288
110
716
1.59
4.76
1.9
1.7
—
—
—
0
0
262
2026
1.37
4.70
5.7
4.2
1.02
1.02
kg/l
0.72
45
325
21
74
2.87
4.67
1.7
1.1
6.67
2.66
u/ml
0.58
15
32
356
2889
1.33
4.64
3.8
3.3
0.53
0.47
e6/l
0.15
299
2279
81
494
1.68
4.54
2.2
1.9
—
—
—
0
0
522
4476
1.29
4.48
6.6
5.2
0.00
0.00
estimate
-0.00
100
867
528
4549
1.28
4.32
5.0
3.9
0.00
0.00
estimate
0.50
93
844
176
1292
1.42
4.27
9.8
8.5
—
—
—
0
0
31
139
2.26
4.27
9.4
7.3
6.76
7.38
mmol/l
0.70
26
114
432
3643
1.29
4.15
2.4
2.2
76.30
78.39
nmol/l
0.81
384
3145
416
3493
1.29
4.13
5.4
4.2
—
—
—
0
0
89
574
1.59
4.03
1.8
1.9
1.44
1.54
g/l
0.44
74
502
9
14
6.47
3.98
1.0
1.1
—
—
—
0
0
145
1045
1.44
3.90
3.5
2.6
7.73
10.60
umol/l
1.92
131
930
95
630
1.55
3.83
3.5
2.8
0.59
0.33
e6/l
0.48
95
619
112
770
1.50
3.83
3.1
3.1
54.77
58.42
ml/min/173m2
0.41
43
335
55
317
1.77
3.81
1.6
1.6
—
—
—
0
0
28
128
2.21
3.72
1.1
1.2
—
—
—
0
0
58
343
1.72
3.68
1.4
1.2
—
—
—
0
0
110
765
1.48
3.57
3.5
3.8
109.65
98.72
ng/l
0.52
90
658
107
740
1.49
3.57
2.0
2.2
355.94
368.72
nmol/l
0.34
96
668
6
6
10.04
3.50
1.0
1.3
—
—
—
0
0
42
230
1.86
3.45
1.4
1.7
—
—
—
0
0
71
453
1.60
3.40
5.3
4.9
24.35
25.05
mmol/l
1.21
66
419
9
18
5.03
3.37
1.0
1.1
—
—
—
0
0
9
18
5.03
3.37
1.0
1.1
—
—
—
0
0
9
18
5.03
3.37
1.1
1.1
—
—
—
0
0
50
293
1.74
3.31
1.7
1.8
—
—
—
0
0
101
704
1.47
3.26
2.0
1.6
1.83
1.53
%
1.79
87
584
9
19
4.76
3.24
1.1
1.2
—
—
—
0
0
9
19
4.76
3.24
1.1
1.2
—
—
—
0
0
74
484
1.56
3.21
7.6
4.4
1.53
1.59
%
0.31
69
451
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
44
2.98
3.14
1.0
1.1
—
—
—
0
0
738
6764
1.23
3.05
4.7
4.1
15.99
14.35
mm/h
1.57
681
6128
220
1764
1.30
3.03
3.1
3.0
1.57
1.09
e6/l
0.41
136
1076
210
1674
1.31
3.02
3.3
3.2
2.89
1.84
e6/l
0.80
128
992
17
69
2.48
2.96
1.7
1.3
—
—
—
0
0
25
121
2.09
2.94
1.0
1.3
251.20
307.36
u/ml
0.52
15
66
44
258
1.73
2.93
1.7
2.2
131.19
128.39
g/l
0.32
37
192
17
70
2.45
2.88
1.7
1.3
—
—
—
0
0
6
9
6.69
2.87
1.2
1.4
—
—
—
0
0
991
9405
1.27
2.84
14.4
10.9
25.53
24.86
u/l
0.44
950
8952
16
66
2.44
2.71
1.1
1.0
26.80
42.29
ng/l
—
5
38
16
66
2.44
2.71
1.1
1.0
411.80
611.39
ng/l
—
5
38
16
66
2.44
2.71
1.1
1.0
177.80
308.46
ng/l
—
5
39
6
10
6.02
2.70
1.2
1.3
—
—
—
0
0
42
250
1.70
2.68
2.3
2.6
16.79
15.71
%
1.24
27
133
1019
9722
1.27
2.67
37.4
24.9
229.15
235.83
e9/l
2.34
991
9384
1019
9723
1.27
2.66
38.0
25.0
38.71
39.38
%
2.45
924
8856
1019
9725
1.27
2.64
37.4
24.9
4.29
4.40
e12/l
8.22
991
9350
22
106
2.09
2.64
1.9
1.6
—
—
—
0
0
1019
9727
1.27
2.62
37.7
25.1
129.58
133.25
g/l
10.23
1002
9502
15
61
2.48
2.62
2.2
2.3
—
—
—
0
0
128
972
1.35
2.58
3.0
2.7
65.35
66.00
g/l
0.40
115
873
144
1114
1.33
2.57
3.7
3.8
—
—
—
0
0
11
36
3.07
2.56
1.0
1.2
—
—
—
0
0
6
11
5.48
2.54
1.7
1.0
—
—
—
0
0
237
1967
1.25
2.46
3.0
3.1
2.46
2.46
mmol/l
0.26
214
1711
8
21
3.83
2.46
12.4
18.3
1124.75
1376.71
nmol/l
—
8
21
8
21
3.83
2.46
8.4
12.8
624.75
796.62
nmol/l
—
8
21
22
110
2.02
2.41
3.3
2.7
—
—
—
0
0
11
38
2.91
2.41
2.1
1.4
59.17
61.12
umol/l
—
6
25
6
12
5.02
2.40
1.7
1.0
—
—
—
0
0
41
253
1.64
2.32
10.5
5.7
106.25
105.09
mmol/l
0.69
36
222
7
18
3.90
2.25
2.4
2.3
31105.86
41228.06
ug/l
—
7
18
13
54
2.42
2.20
1.8
1.3
—
—
—
0
0
13
54
2.42
2.20
1.8
1.3
—
—
—
0
0
10
36
2.79
2.14
1.3
2.6
—
—
—
0
0
10
36
2.79
2.14
1.3
2.6
—
—
—
0
0
13
55
2.38
2.12
1.8
2.2
—
—
—
0
0
11
43
2.57
2.08
11.9
6.4
67.91
74.68
%
0.32
11
34
5
10
5.02
2.07
1.2
1.3
—
—
—
0
0
5
10
5.02
2.07
1.0
1.1
—
—
—
0
0
56
384
1.48
2.05
4.0
3.6
2.48
2.07
ratio
—
6
34
122
956
1.31
2.02
2.8
2.1
0.20
0.20
g/l
0.04
115
889
57
395
1.46
1.99
4.1
3.6
47.46
72.61
mg/l
0.84
46
320
7
21
3.35
1.96
1.0
1.2
—
—
—
0
0
53
363
1.48
1.96
2.3
2.6
0.70
1.43
g/l
1.39
41
302
15
71
2.13
1.92
1.2
1.1
110.47
111.34
%
0.03
15
61
847
8030
1.17
1.87
4.8
4.4
2.04
2.09
mu/l
0.40
758
7116
8
28
2.87
1.86
1.4
1.1
—
—
—
0
0
34
214
1.61
1.84
4.1
3.9
1.24
1.51
%
0.25
25
185
27
160
1.70
1.83
1.4
1.2
—
—
—
0
0
876
8338
1.17
1.80
23.8
16.2
70.84
72.35
ml/min/173m2
1.28
761
6896
24
139
1.74
1.76
4.8
3.9
53.92
55.55
%
0.11
18
120
302
2654
1.18
1.75
3.8
2.9
374.13
7185.07
umol/l
9.84
255
2261
462
4204
1.16
1.72
2.6
2.4
—
—
—
0
0
7
25
2.81
1.65
2.0
1.1
—
—
—
0
0
41
278
1.49
1.63
1.6
1.5
279.38
265.20
ug/g
0.18
24
170
55
395
1.41
1.63
4.2
3.6
34.66
72.62
mg/l
0.66
45
324
44
304
1.46
1.60
1.8
2.4
0.00
0.05
g/l
1.35
37
277
12
57
2.12
1.55
1.3
1.2
—
—
—
0
0
5
15
3.34
1.52
1.2
1.2
—
—
—
0
0
369
3333
1.15
1.49
4.0
3.8
14.23
8.63
mg/mmol
1.23
263
2172
877
8398
1.15
1.48
6.9
6.5
41.72
40.97
mmol/mol
1.37
801
7599
17
94
1.82
1.47
1.3
1.3
—
—
—
0
0
54
396
1.38
1.45
1.7
2.5
3.10
3.02
g/l
0.18
43
345
14
73
1.93
1.44
1.3
1.1
—
—
—
0
0
5
16
3.13
1.44
1.0
1.2
—
—
—
0
0
5
17
2.95
1.36
1.0
1.1
—
—
—
0
0
45
326
1.39
1.31
1.8
2.3
37.34
37.16
g/l
0.07
33
275
40
284
1.42
1.31
2.3
2.3
128.69
122.44
ug/min
0.04
25
164
8
34
2.36
1.29
1.1
1.1
—
—
—
0
0
104
853
1.24
1.26
4.4
4.0
1.21
1.22
mmol/l
0.50
93
736
57
433
1.33
1.25
1.7
2.5
3.89
3.70
g/l
0.45
46
382
28
187
1.51
1.24
1.7
1.6
—
—
—
0
0
6
25
2.41
1.24
1.5
1.8
—
—
—
0
0
57
434
1.33
1.24
1.7
2.5
—
—
—
0
0
12
63
1.91
1.23
1.0
1.0
—
—
—
0
0
18
108
1.68
1.22
1.3
1.8
—
—
—
0
0
57
435
1.33
1.22
1.7
2.5
7.45
7.44
g/l
0.01
46
384
5
19
2.64
1.21
1.4
1.0
1646.40
1324.63
miu/ml
—
5
19
349
3185
1.13
1.19
3.4
3.2
7.26
7.46
mmol/l
0.39
292
2611
22
141
1.57
1.17
2.7
3.2
—
2769.38
—
0
16
17
102
1.68
1.16
1.3
1.8
—
—
—
0
0
16
95
1.69
1.14
1.3
1.3
—
—
—
0
0
678
6449
1.11
1.11
4.0
3.6
15.07
15.08
pmol/l
0.01
611
5695
342
3134
1.13
1.09
3.4
3.3
245.76
241.74
mg/l
0.01
246
2071
16
98
1.64
1.03
1.5
1.2
0.74
0.64
nmol/l
0.63
16
91
846
8164
1.11
1.02
4.2
4.1
1.29
1.26
mmol/l
0.63
761
7198
10
53
1.89
1.01
1.5
1.6
2757.09
58.60
u/l
—
5
12
21
139
1.52
1.00
1.1
1.1
—
—
—
0
0
7
35
2.01
1.00
1.3
1.5
—
—
—
0
0
11
61
1.81
0.98
2.5
1.5
107.45
92.43
umol/l
0.24
11
61
11
61
1.81
0.98
2.8
2.9
44.60
38.32
u/ml
0.10
11
61
10
54
1.86
0.96
1.6
1.4
—
—
—
0
0
10
54
1.86
0.96
1.6
1.4
—
—
—
0
0
28
199
1.42
0.96
1.4
1.2
3.28
7.00
u/ml
—
5
25
6
27
2.23
0.93
1.2
1.0
176.83
157.67
iu/ml
—
6
27
10
55
1.82
0.92
1.1
1.1
—
—
—
0
0
51
403
1.28
0.90
2.9
3.0
4.31
4.40
pmol/l
0.21
45
343
31
228
1.37
0.89
1.4
1.4
—
—
—
0
0
28
381
0.73
0.89
1.6
1.8
—
—
—
0
0
8
42
1.91
0.88
1.1
1.3
—
—
—
0
0
8
42
1.91
0.88
1.3
4.9
—
38.71
—
0
7
24
169
1.43
0.88
1.5
1.3
13889.13
106910.13
e6/l
1.48
16
100
523
4959
1.09
0.85
5.8
5.7
7.68
4.32
ug/l
0.39
468
4363
27
196
1.39
0.84
1.4
1.7
—
—
—
0
0
6
31
1.94
0.84
1.0
1.6
—
—
—
0
0
53
426
1.26
0.83
3.1
2.8
—
—
—
0
0
8
47
1.71
0.80
1.3
1.2
165.34
182.30
pmol/l
—
8
47
10
164
0.61
0.80
1.0
1.1
—
—
—
0
0
31
233
1.34
0.80
1.4
1.6
16195.71
18797.63
e6/l
0.16
21
165
895
8711
1.10
0.78
5.2
5.0
6.18
6.11
mmol/l
0.89
791
7706
13
83
1.57
0.75
1.6
1.1
44.31
50.90
u/l
0.39
13
73
121
1065
1.15
0.74
4.4
3.0
327.03
246.61
ng/l
0.60
113
975
50
406
1.24
0.74
1.7
2.5
10.93
10.60
g/l
0.18
38
354
19
133
1.44
0.74
1.5
1.4
—
—
—
0
0
7
38
1.85
0.73
1.0
1.0
—
—
—
0
0
39
308
1.27
0.73
1.0
1.0
—
—
—
0
0
33
256
1.30
0.70
1.3
1.6
—
—
—
0
0
25
186
1.35
0.70
1.5
1.4
767.21
1764.92
e6/l
2.70
19
133
21
152
1.39
0.69
1.1
1.5
—
—
—
0
0
19
135
1.41
0.69
1.5
1.4
—
—
—
0
0
19
135
1.41
0.69
1.5
1.4
—
—
—
0
0
19
135
1.41
0.69
1.5
1.4
—
—
—
0
0
36
284
1.28
0.68
1.9
2.4
0.00
0.00
g/l
-0.00
31
259
76
883
0.85
0.67
1.2
1.3
—
—
—
0
0
19
136
1.40
0.67
1.5
1.4
—
—
—
0
0
19
136
1.40
0.67
1.5
1.4
—
—
—
0
0
7
43
1.63
0.67
1.7
1.0
66.57
88.53
u/l
—
7
38
5
28
1.79
0.66
1.2
1.2
—
—
—
0
0
12
78
1.54
0.65
1.1
1.2
—
—
—
0
0
25
189
1.33
0.64
1.1
1.4
—
—
—
0
0
422
4009
1.08
0.63
5.1
4.9
22.83
21.74
%
0.77
235
2174
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.1
—
21.47
—
0
17
0
22
0.00
0.59
0.0
1.5
—
—
—
0
0
42
346
1.22
0.58
1.8
1.9
37.20
37.69
u/l
0.06
35
298
6
36
1.67
0.56
1.2
1.0
—
—
—
0
0
6
36
1.67
0.56
4.2
2.1
800.50
1732.25
u/ml
—
6
36
20
151
1.33
0.54
1.6
1.5
3.84
6.94
iu/l
—
9
42
168
1547
1.10
0.53
1.2
1.2
0.85
1.20
u/ml
0.96
42
366
109
1209
0.89
0.53
1.2
1.2
25.35
12.72
u/ml
0.63
37
415
6
97
0.62
0.52
1.2
1.1
—
—
—
0
0
14
101
1.39
0.49
1.2
1.4
15.93
13.90
u/l
0.41
14
93
85
758
1.13
0.48
2.5
2.2
11.63
12.29
nmol/l
0.21
76
649
7
47
1.49
0.47
1.1
1.4
0.16
0.21
nmol/l
—
7
31
14
102
1.38
0.47
1.4
1.4
67.43
69.61
%
—
7
72
7
50
1.40
0.45
1.4
1.1
—
—
—
0
0
871
8549
1.06
0.44
4.8
4.6
4.16
4.42
mmol/l
10.84
792
7673
22
274
0.80
0.43
1.6
1.6
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.5
—
—
—
0
0
5
34
1.47
0.40
3.6
2.0
18.00
15.77
nmol/l
—
5
29
5
34
1.47
0.40
1.0
1.1
—
—
—
0
0
894
8793
1.06
0.40
5.3
5.2
2.36
2.57
mmol/l
9.56
805
7855
28
232
1.21
0.40
1.5
1.3
—
—
—
0
0
28
232
1.21
0.40
1.5
1.3
—
—
—
0
0
29
242
1.20
0.39
1.5
1.5
0.16
22.40
iu/ml
—
9
54
760
7447
1.05
0.38
29.4
19.7
15.22
15.43
%
0.51
752
7298
9
66
1.37
0.38
3.7
3.6
—
—
—
0
0
25
301
0.83
0.38
1.6
1.7
—
—
—
0
0
9
68
1.33
0.37
1.1
1.1
—
—
—
0
0
21
171
1.23
0.36
1.1
1.4
—
—
—
0
0
42
367
1.15
0.35
1.1
1.2
89.52
148.72
iu/ml
0.80
16
125
118
1269
0.92
0.34
1.2
1.3
67.72
38.88
iu/ml
0.70
38
394
15
188
0.80
0.33
1.1
1.5
1.50
0.81
nmol/l
—
9
155
6
46
1.31
0.33
1.7
1.8
—
—
—
0
0
6
46
1.31
0.33
1.7
1.8
—
—
—
0
0
6
47
1.28
0.32
1.7
1.1
48.83
23.16
u/l
—
6
38
17
137
1.24
0.32
1.7
1.2
—
—
—
0
0
293
2816
1.05
0.32
3.5
3.3
1.27
0.80
ug/l
1.33
204
2032
7
52
1.35
0.31
1.0
1.3
213.43
584.32
u/l
—
7
47
856
8437
1.05
0.31
4.8
4.6
1.33
1.42
mmol/l
7.53
768
7509
45
401
1.13
0.29
4.4
3.2
328.54
4208.83
u/ml
0.86
37
334
23
195
1.18
0.28
1.0
1.1
—
6.93
—
0
14
27
234
1.16
0.26
1.3
1.3
—
—
—
0
0
12
95
1.27
0.26
1.4
1.9
—
—
—
0
0
6
83
0.72
0.24
1.0
1.0
—
1.37
—
0
28
14
115
1.22
0.23
1.1
1.5
—
—
—
0
0
14
115
1.22
0.23
1.1
1.5
—
—
—
0
0
13
106
1.23
0.23
1.4
1.6
—
—
—
0
0
13
106
1.23
0.23
1.4
1.6
—
—
—
0
0
13
106
1.23
0.23
1.4
1.6
—
—
—
0
0
5
39
1.28
0.23
1.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
4.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
0.75
—
0
12
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
6
48
1.25
0.20
1.7
1.8
—
—
—
0
0
6
48
1.25
0.20
1.0
1.2
—
—
—
0
0
6
48
1.25
0.20
1.0
1.2
—
—
—
0
0
6
53
1.13
0.18
1.7
1.1
171.67
94.56
u/l
—
6
45
13
109
1.19
0.18
1.2
1.0
—
—
—
0
0
30
271
1.11
0.18
1.3
1.6
—
—
—
0
0
10
121
0.83
0.18
3.2
3.3
—
—
—
0
0
27
299
0.90
0.17
1.3
1.2
—
—
—
0
0
10
82
1.22
0.17
1.0
1.6
—
—
—
0
0
7
63
1.11
0.17
2.4
3.8
—
—
—
0
0
20
177
1.13
0.16
1.3
1.6
—
—
—
0
0
20
177
1.13
0.16
1.3
1.6
—
—
—
0
0
8
70
1.14
0.16
1.4
1.2
—
—
—
0
0
24
216
1.11
0.15
1.4
1.6
—
—
—
0
0
15
170
0.88
0.13
4.3
3.0
4.45
4.51
e9/l
0.04
15
170
15
169
0.89
0.12
1.3
1.3
—
—
—
0
0
23
212
1.09
0.10
1.5
1.6
3.49
3.09
mg/l
0.13
17
168
5
44
1.14
0.10
1.2
1.4
0.98
0.91
g/l
—
5
44
16
176
0.91
0.09
4.2
3.3
60.00
58.95
%
0.18
16
176
5
48
1.04
0.09
1.2
1.5
—
—
—
0
0
6
54
1.11
0.09
2.3
3.8
105.67
110.20
nmol/l
—
6
54
5
62
0.81
0.08
1.2
1.5
—
—
—
0
0
5
62
0.81
0.08
1.2
1.5
—
—
—
0
0
7
66
1.06
0.08
1.1
1.2
—
—
—
0
0
8
76
1.05
0.07
1.3
1.9
—
—
—
0
0
12
108
1.11
0.07
1.9
2.2
—
—
—
0
0
8
78
1.03
0.07
1.1
1.4
—
—
—
0
0
60
620
0.97
0.07
1.4
1.4
—
—
—
0
0
25
236
1.06
0.06
1.2
1.1
—
—
—
0
0
225
2278
0.98
0.06
1.7
1.6
1.39
1.31
mmol/l
0.70
180
1850
25
237
1.06
0.05
1.2
1.1
—
—
—
0
0
26
247
1.05
0.05
3.0
3.4
28.89
32.15
mg/l
0.16
19
155
13
140
0.93
0.04
1.4
1.4
7.08
6.26
mmol/l
0.55
13
131
25
261
0.96
0.04
1.3
1.5
—
—
—
0
0
28
269
1.04
0.04
1.3
1.3
—
—
—
0
0
82
832
0.98
0.03
3.5
2.5
29.67
33.42
u/l
0.86
72
691
124
1227
1.01
0.02
5.2
4.7
33.65
32.79
%
0.30
82
774
16
154
1.04
0.00
1.2
1.4
—
—
—
0
0
13
132
0.98
0.00
2.2
1.9
209.92
226.56
pmol/l
0.15
13
122
17
168
1.01
0.00
1.1
1.1
—
—
—
0
0
118
1182
1.00
0.00
4.0
4.0
51.38
30.63
ug/l
0.26
101
1000
10
97
1.03
0.00
1.2
1.6
—
—
—
0
0
13
127
1.02
0.00
1.2
1.3
—
—
—
0
0
16
155
1.03
0.00
1.3
1.6
—
—
—
0
0
13
125
1.04
0.00
1.2
1.6
—
—
—
0
0
7
72
0.97
0.00
1.1
1.3
—
60.00
—
0
6
6
64
0.94
0.00
1.7
1.7
—
—
—
0
0
6
64
0.94
0.00
1.7
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
24.16
—
0
8
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
-0.00
2.0
1.5
2.40
9.44
u/l
—
5
45
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
78.00
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
0.03
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
9
93
0.97
-0.00
1.3
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_OTHINTRACRA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_OTHINTRACRA | 2.148 [1.85, 2.49] | < 0.001 |
| Birth year | 0.996 [0.99, 1.0] | 0.346 |
During the follow-up period (1.1.1998 — 31.12.2019), 1445 out of 2816 females with I9_OTHINTRACRA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_OTHINTRACRA | 2.024 [1.74, 2.35] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 2569 out of 4843 males with I9_OTHINTRACRA died.
Mortality risk
Mortality risk for people of age
years, who have I9_OTHINTRACRA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.205% | 0.342% |
| 5 | 1.286% | 2.021% |
| 10 | 3.13% | 5.194% |
| 15 | 6.112% | 10.143% |
| 20 | 10.484% | 17.079% |
Relationships between endpoints
↥Index endpoint: I9_OTHINTRACRA – Other intracranial haemorrhages
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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