Other intracranial haemorrhages

I9_OTHINTRACRA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I62
  • Cause of death: ICD-10 I62

2 out of 7 registries used, show all original rules.

1124

4. Check minimum number of events

None

1124

5. Include endpoints

None

1124

6. Filter based on genotype QC (FinnGen only)

1124

Control definitions (FinnGen only)

Control exclude
I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I60-I69
Name in latin
Alia haemorrhagia intracranialis non traumatica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 10757 4015 6617
Only index persons 8357 3132 5225
Unadjusted period prevalence (%)
Whole population 0.16 0.12 0.18
Only index persons 0.17 0.12 0.20
Median age at first event (years)
Whole population 74.17 76.06 73.01
Only index persons 73.90 75.44 72.98

-FinnGen-

Key figures

All Female Male
Number of individuals 1124 356 768
Unadjusted period prevalence (%) 0.27 0.12 0.34
Median age at first event (years) 72.47 69.31 73.94

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1013
Matched controls
10130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
64.4
323.0
512
158
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
121.7
323.0
422
59
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
16384.0
323.0
770
*
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
+∞
237.0
218
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
139.8
193.4
202
18
AA1AD
NOMESCO Finland
CT of head and brain
8.0
190.0
572
1414
I62.1
ICD-10 Finland
Nontraumatic extradural haemorrhage
+∞
115.9
109
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
58.9
110.0
129
25
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
+∞
76.0
72
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
3.6
75.4
490
2096
X59
ICD-10 Finland
Exposure to unspecified factor
4.4
74.4
321
958
W19
ICD-10 Finland
Unspecified fall
5.6
66.9
218
475
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
332.5
62.1
62
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
19.2
60.2
93
53
K90
ICPC
Stroke/cerebrovascular accident
29.2
59.7
81
30
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
85.3
57.7
64
8
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
589.6
57.2
56
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
+∞
56.8
54
*
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
273.9
51.6
52
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
7.4
42.2
105
156
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.1
41.5
283
1140
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
40.9
39
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
+∞
40.9
39
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
413.0
40.4
40
*
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
413.0
40.4
40
*
N03AX14
ATC
levetiracetam; systemic
13.0
40.2
72
59
G91.2
ICD-10 Finland
Normal-pressure hydrocephalus
10.9
38.9
76
75
R51.80
ICD-10 Finland
Headache
3.7
35.2
168
512
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
+∞
33.5
32
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.8
31.4
230
948
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
25.1
29.4
41
17
AAF00
NOMESCO Finland
Ventriculostomy
58.5
29.3
34
6
G91.0
ICD-10 Finland
Communicating hydrocephalus
28.9
29.1
39
14
B01AA03
ATC
warfarin; systemic
2.3
29.0
356
1936
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.7
28.1
99
226
K91
ICPC
Cerebrovascular disease
23.1
28.0
40
18
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
277.9
26.8
27
*
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
99.4
26.8
29
*
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
+∞
26.1
25
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
7.3
25.5
62
89
AAD12
NOMESCO Finland
Drainage of subdural fluid
51.4
25.3
30
6
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
25.0
377
2214
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
245.4
23.7
24
*
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
10.2
22.7
45
46
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.5
22.7
114
358
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.9
22.4
97
269
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
22.4
221
1057
R42
ICD-10 Finland
Dizziness and giddiness
2.2
21.7
263
1387
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
117.5
21.6
23
*
XA800
NOMESCO Finland
Neuropsychological investigation
7.8
21.6
50
67
T90.5
ICD-10 Finland
Sequelae of intracranial injury
11.5
21.6
40
36
WX002
NOMESCO Finland
Sedation and analgesia
2.3
21.5
243
1240
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.4
21.3
107
336
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
20.9
20
*
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
9.7
20.7
42
45
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
9.1
20.0
42
48
R53
ICD-10 Finland
Malaise and fatigue
2.2
19.3
238
1255
N02BE01
ATC
paracetamol; systemic, rectal
2.1
19.0
832
6979
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
19.0
658
5072
N03AF02
ATC
oxcarbazepine; oral
6.3
18.7
50
83
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
14.5
18.6
31
22
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.8
18.4
80
223
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
7.8
18.3
42
56
N03AB02
ATC
phenytoin; systemic
10.9
18.0
34
32
R41.0
ICD-10 Finland
Disorientation, unspecified
4.3
17.8
67
164
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
12.7
17.7
31
25
N03AG01
ATC
valproic acid; systemic, rectal
4.3
17.7
67
165
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
29.3
17.5
23
8
R56.8
ICD-10 Finland
Other and unspecified convulsions
4.2
17.4
68
172
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
+∞
16.7
16
*
C07AB07
ATC
bisoprolol; oral
1.7
16.3
555
4152
N19
ICPC
Speech disorder
13.8
16.0
27
20
N18
ICPC
Paralysis/weakness
9.7
16.0
32
34
S06.0
ICD-10 Finland
Concussion
2.7
15.8
116
468
S06.3
ICD-10 Finland
Focal brain injury
8.5
15.8
34
41
AA1AA
NOMESCO Finland
Head X-ray examination
10.6
15.8
30
29
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
26.7
15.6
21
8
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
4.7
15.1
51
112
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.6
15.1
117
488
N05AH04
ATC
quetiapine; oral
2.3
15.0
146
685
R47.0
ICD-10 Finland
Dysphasia and aphasia
25.4
14.7
20
8
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
14.6
14
*
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
+∞
14.6
14
*
PA2AD
NOMESCO Finland
CT angiography of brain
43.1
14.1
17
*
R4120
NOMESCO Finland
Occupational therapy
3.6
14.0
63
182
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
13.9
202
1127
SPAT1216
SPAT
Assessment of functional ability
2.0
13.9
200
1111
N80
ICPC
Head injury other
6.7
13.6
34
52
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
+∞
13.6
13
*
S06.9
ICD-10 Finland
Intracranial injury, unspecified
16.4
13.5
21
13
WX110
NOMESCO Finland
Local anesthesy
1.6
13.3
567
4412
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
13.1
74
251
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
19.3
12.9
19
10
P20
ICPC
Memory disturbance
2.0
12.9
176
953
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
12.8
196
1110
H53.4
ICD-10 Finland
Visual field defects
7.3
12.8
30
42
SPAT1234
SPAT
Support of social functional capacity
2.8
12.6
81
300
R4150
NOMESCO Finland
Neuropsychological rehabilitation
70.7
12.6
14
*
SPAT1229
SPAT
Assessment of need for aid
2.4
12.6
110
488
G91.1
ICD-10 Finland
Obstructive hydrocephalus
20.3
12.5
18
9
N06AX11
ATC
mirtazapine; oral
1.7
12.3
279
1807
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.6
12.0
54
156
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
11.9
460
3448
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
47.2
11.9
14
*
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
9.1
11.8
24
27
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.3
11.7
35
68
I63.8
ICD-10 Finland
Other cerebral infarction
+∞
11.5
11
*
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
+∞
11.5
11
*
X58
ICD-10 Finland
Exposure to other specified factors
2.2
11.4
122
597
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
35.4
11.3
14
*
L28
ICPC
Limited function/disability (L)
1.9
11.1
191
1126
Y96.9
ICD-10 Finland
Unspecified type of accident
5.8
10.9
30
53
N05AX08
ATC
risperidone; systemic
2.3
10.6
100
461
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
+∞
10.4
10
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
10.4
99
458
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
10.4
188
1124
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
32.9
10.3
13
*
PA7BD
NOMESCO Finland
CT angiography of neck and brain
7.2
10.3
24
34
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.7
10.2
68
261
N05CF01
ATC
zopiclone; oral
1.6
10.1
339
2423
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
10.1
139
755
AA5PD
NOMESCO Finland
CT examination of brain pefusion
40.5
10.0
12
*
C09AA02
ATC
enalapril; systemic
1.7
9.9
240
1568
G40.10
ICD-10 Finland
Simple partial seizures
11.5
9.6
17
15
SPAT1053
SPAT
Memory test
1.7
9.5
215
1377
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
9.4
276
1900
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
+∞
9.4
9
*
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
+∞
9.4
9
*
I62
ICD-10 Finland
Other nontraumatic intracranial haemorrhage
+∞
9.4
9
*
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
9.4
9
*
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
+∞
9.4
9
*
R11
ICD-10 Finland
Nausea and vomiting
2.4
9.4
79
345
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
21.9
9.4
13
6
WX892
NOMESCO Finland
Monitored bed care
2.3
9.3
84
381
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.8
8.9
56
206
WX882
NOMESCO Finland
High dependency care
3.5
8.9
40
117
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
18.8
8.9
13
7
FFW96
NOMESCO Finland
Other operation on atria
24.2
8.9
12
5
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
3.2
8.9
45
145
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
8.9
203
1300
NA1AD
NOMESCO Finland
Cervical spine CT examination
3.0
8.7
47
159
N03AF01
ATC
carbamazepine; oral, rectal
2.7
8.6
58
224
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
8.6
309
2229
N05BA04
ATC
oxazepam; oral
1.6
8.5
221
1466
S01.0
ICD-10 Finland
Open wound of scalp
2.2
8.4
86
413
ABB40
NOMESCO Finland
Evacuation of spontaneous haematoma of spinal canal
90.7
8.4
9
*
AAD15
NOMESCO Finland
Evacuation of traumatic intracerebral haematoma
90.7
8.4
9
*
N29
ICPC
Neurological sympt/complt other
4.5
8.4
28
63
F05.9
ICD-10 Finland
Delirium, unspecified
3.7
8.4
35
97
A28
ICPC
Limited function/disability NOS
1.7
8.4
188
1198
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
+∞
8.3
8
*
AAF99
NOMESCO Finland
Other shunt operation on ventricle of brain or intracerebral cyst
33.6
8.1
10
*
G41.9
ICD-10 Finland
Status epilepticus, unspecified
9.0
8.0
16
18
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.1
8.0
85
414
SPAT1254
SPAT
Administration of medicine
1.7
8.0
163
1007
C10AA01
ATC
simvastatin; oral
1.5
7.9
472
3783
R50.9
ICD-10 Finland
Fever, unspecified
1.8
7.8
137
808
G81.9
ICD-10 Finland
Hemiplegia, unspecified
9.5
7.8
15
16
W00
ICD-10 Finland
Fall on same level involving ice and snow
2.1
7.7
91
463
B01AC07
ATC
dipyridamole; systemic
2.3
7.6
70
320
R55
ICD-10 Finland
Syncope and collapse
1.8
7.6
128
744
S06.4
ICD-10 Finland
Epidural haemorrhage
25.2
7.6
10
*
N99
ICPC
Neurological disease other
6.2
7.6
19
31
G72.8
ICD-10 Finland
Other specified myopathies
4.2
7.5
27
66
J01MA02
ATC
ciprofloxacin; systemic
1.5
7.5
394
3064
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
7.5
236
1640
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.3
7.4
35
108
F00.20*G30.8
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
3.3
7.4
35
108
Z98.2
ICD-10 Finland
Presence of cerebrospinal fluid drainage device
80.6
7.4
8
*
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.9
7.3
112
629
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
+∞
7.3
7
*
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
+∞
7.3
7
*
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
+∞
7.3
7
*
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
+∞
7.3
7
*
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
9.4
7.3
14
15
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.9
7.3
104
570
X57
ICD-10 Finland
Unspecified privation
3.7
7.1
29
80
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.5
7.1
53
219
XX3XW
NOMESCO Finland
NA
12.1
7.1
12
10
A04
ICPC
Weakness/tiredness general
1.8
7.1
124
732
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
10.1
7.0
13
13
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
7.0
7.0
16
23
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
6.4
6.9
17
27
W10
ICD-10 Finland
Fall on and from stairs and steps
2.6
6.9
49
197
N03AX18
ATC
lacosamide; systemic
13.9
6.9
11
8
B01AB05
ATC
enoxaparin; parenteral
1.5
6.9
285
2103
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
6.8
148
931
SPAT1360
SPAT
Extensive global examination
2.0
6.8
81
416
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.8
6.8
27
73
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.4
6.8
19
36
ZXA05
NOMESCO Finland
Left side
1.5
6.8
256
1850
Z43.0
ICD-10 Finland
Attention to tracheostomy
40.3
6.8
8
*
G41.0
ICD-10 Finland
Grand mal status epilepticus
40.3
6.8
8
*
F00.20
ICD-10 Finland
Dementia in Alzheimer's disease, atypical or mixed type without additional symptoms
5.0
6.7
20
41
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
22.7
6.7
9
*
G30.8
ICD-10 Finland
Other Alzheimer disease
3.0
6.6
36
124
PA6AD
NOMESCO Finland
CT of neck arteries
8.8
6.6
13
15
N28
ICPC
Limited function/disability (N)
4.4
6.6
22
51
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
6.5
146
927
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
6.5
68
333
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
6.4
188
1279
T24.3
ICD-10 Finland
Burn of third degree of hip and lower limb, except ankle and foot
70.2
6.4
7
*
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.2
6.3
64
307
A41.9
ICD-10 Finland
Sepsis, unspecified
2.5
6.3
48
201
J01DB01
ATC
cefalexin; oral
1.4
6.3
708
6271
N88
ICPC
Epilepsy
18.1
6.3
9
5
F03
ICD-10 Finland
Unspecified dementia
2.1
6.3
70
349
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
+∞
6.3
6
*
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
+∞
6.3
6
*
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
+∞
6.3
6
*
C03AA03
ATC
hydrochlorothiazide; oral
1.8
6.2
108
635
K78
ICPC
Atrial fibrillation/flutter
1.8
6.2
106
619
N05CD07
ATC
temazepam; oral
1.6
6.2
146
942
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
5.8
6.2
16
28
C03CA01
ATC
furosemide; systemic
1.4
6.1
381
3035
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.6
6.1
43
172
G40.89
ICD-10 Finland
Other epilepsy
12.6
6.1
10
8
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
12.6
6.1
10
8
T85.0
ICD-10 Finland
Mechanical complication of ventricular intracranial (communicating) shunt
12.6
6.1
10
8
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
6.1
65
321
SPAT1252
SPAT
Overall medication plan or its review
1.9
6.0
83
450
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
4.2
6.0
21
51
R1250
NOMESCO Finland
Evaluation of functional capability
3.6
6.0
25
71
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.0
126
785
N05AA02
ATC
levomepromazine; systemic
2.7
6.0
39
149

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
323
1254
3.21
62.61
2.3
1.9
30.4
30.2
s
0.17
314
1211
477
2473
2.61
52.05
2.9
2.0
281.7
289.1
u/l
0.04
461
2286
744
5220
2.26
35.70
7.6
4.8
6.9
6.9
mmol/l
0.09
719
4919
463
2742
2.17
33.60
3.3
2.6
—
—
—
0
0
602
3953
2.13
33.26
13.9
11.5
1.4
1.4
inr
0.04
173
1095
69
142
5.11
31.99
2.2
1.3
47.9
66.9
e6/l
0.14
55
113
69
142
5.11
31.99
2.3
1.4
31173.3
1071.7
e6/l
0.51
59
117
592
3906
2.09
31.79
5.0
4.3
—
—
—
0
0
281
1420
2.31
29.53
3.2
3.1
0.8
0.8
mmol/l
0.10
271
1312
459
2893
1.99
26.57
4.6
4.3
—
—
—
0
0
361
2088
2.07
26.56
3.2
2.5
—
—
—
0
0
54
111
5.06
25.05
2.2
1.2
—
—
—
0
0
535
3678
1.87
22.82
5.2
4.1
37.2
60.2
ng/l
1.32
455
2835
75
218
3.61
22.14
2.8
2.1
21.0
22.2
s
0.86
70
196
225
1156
2.18
22.07
8.5
6.8
1.2
1.3
mmol/l
0.09
174
877
35
54
6.66
21.83
2.1
1.1
—
—
—
0
0
337
2025
1.95
21.48
5.8
4.1
80.5
83.1
%
1.08
332
1972
221
1152
2.14
20.79
8.6
6.9
4.9
5.1
kpa
1.70
210
1093
220
1151
2.13
20.48
8.6
6.9
13.4
11.6
kpa
4.00
209
1092
618
4586
1.77
19.25
9.1
7.0
1.2
1.2
mmol/l
1.58
531
3856
250
1416
1.98
18.58
37.6
30.6
1.7
1.5
inr
0.91
44
196
416
2784
1.78
18.25
3.6
3.5
—
—
—
0
0
220
1226
1.99
16.99
8.6
6.7
105.4
104.3
mmol/l
2.63
212
1198
173
885
2.13
16.85
6.1
6.6
10.2
11.6
mmol/l
1.64
167
841
220
1230
1.98
16.82
5.4
5.5
1.0
1.0
mmol/l
0.81
209
1135
179
942
2.07
16.15
9.4
7.6
116.7
120.3
g/l
1.51
174
904
192
1045
2.01
15.77
9.0
7.1
96.7
95.1
%
6.26
187
1005
57
173
3.42
15.77
2.5
2.5
28.7
32.9
umol/l
0.91
51
139
552
4160
1.64
14.67
8.7
6.1
1.2
1.2
mmol/l
3.06
498
3722
590
4572
1.61
13.62
7.6
6.2
12.7
12.7
umol/l
0.01
549
4326
126
618
2.17
13.57
9.6
8.7
1.4
1.3
%
0.34
126
613
129
658
2.09
12.54
9.9
6.0
24.8
24.4
mmol/l
0.63
123
614
698
5714
1.58
12.14
6.1
4.8
1714.2
2179.8
e6/l
0.15
18
108
77
321
2.50
12.05
5.8
3.5
3.9
4.0
mmol/l
1.65
70
298
24
51
4.79
10.74
1.7
1.3
1.2
1.0
promille
0.14
19
35
299
2066
1.61
10.51
2.0
1.8
1178.5
1188.0
nmol/l
0.06
231
1524
143
807
1.88
10.37
5.1
3.1
4.8
4.4
kpa
0.80
138
782
267
1805
1.63
10.22
4.7
4.1
134.7
323.4
ng/l
2.67
227
1557
123
669
1.94
9.96
4.4
4.4
5.2
5.2
kpa
0.12
111
612
163
973
1.79
9.85
5.7
3.6
1.3
2.1
mmol/l
1.45
131
764
121
659
1.94
9.76
4.4
4.4
7.4
7.4
ph
0.18
17
77
24
56
4.36
9.61
2.2
1.2
—
—
—
0
0
162
979
1.77
9.37
5.8
3.6
5.7
5.8
kpa
0.96
156
946
127
713
1.88
9.34
6.7
3.9
—
—
—
0
0
165
1008
1.75
9.19
2.1
1.7
—
—
—
0
0
499
3948
1.47
9.09
5.6
4.7
33.5
34.6
g/l
4.15
465
3635
98
510
2.01
9.00
9.6
9.6
24.0
24.5
mmol/l
1.06
92
466
144
863
1.77
8.55
9.2
7.1
1.3
1.4
mmol/l
0.35
136
825
88
459
2.00
8.04
2.1
1.8
3.4
2.4
ug/l
0.25
69
407
15
27
5.62
8.03
4.0
23.4
—
—
—
0
0
199
1325
1.61
7.94
2.1
2.0
—
—
—
0
0
112
643
1.82
7.67
5.3
3.4
126.3
126.6
g/l
0.03
107
629
58
263
2.27
7.60
4.1
4.1
7.8
7.8
kpa
0.00
50
240
355
2730
1.44
7.06
3.1
2.5
60.5
57.3
u/l
0.51
329
2503
560
4685
1.39
6.78
10.8
8.6
4.4
4.3
e9/l
0.25
490
4046
463
3760
1.39
6.66
7.1
5.6
59.1
58.6
%
0.35
428
3478
132
832
1.66
6.51
9.6
7.9
—
—
—
0
0
58
281
2.12
6.50
3.3
3.1
24.8
25.1
mmol/l
0.15
46
234
348
2707
1.41
6.38
4.4
3.9
7.4
7.4
ph
0.77
63
503
269
1998
1.46
6.34
1.4
1.3
—
—
—
0
0
744
6563
1.40
6.33
9.6
7.5
84.7
81.2
u/l
0.92
697
6109
328
2528
1.42
6.33
2.2
2.2
3.5
3.1
mg/l
1.52
274
2128
498
4119
1.38
6.31
7.1
5.5
0.2
0.2
e9/l
0.29
439
3562
880
8009
1.45
6.17
26.7
17.0
26.9
28.2
mg/l
0.57
790
6497
231
1675
1.48
6.15
2.2
1.6
2.0
1.5
mg/l
0.81
187
1326
447
3669
1.36
5.80
7.1
5.6
0.7
0.6
%
0.34
414
3391
465
3842
1.36
5.78
7.5
5.8
25.2
25.9
%
0.64
427
3532
666
5817
1.36
5.73
5.5
4.5
—
—
—
0
0
88
514
1.77
5.72
12.3
9.4
—
—
—
0
0
478
3971
1.35
5.72
6.6
5.3
0.7
0.6
e9/l
1.31
422
3357
455
3758
1.35
5.63
7.1
5.6
2.9
2.9
%
0.10
418
3471
479
3988
1.35
5.62
6.7
5.3
0.0
0.0
e9/l
0.78
427
3384
379
3043
1.37
5.61
3.3
3.4
2.3
2.3
mmol/l
0.10
326
2586
181
1275
1.50
5.53
3.0
2.5
1.8
1.8
%
0.05
159
1118
255
1923
1.42
5.46
3.2
2.9
531.0
562.4
mosm/kgh2o
1.60
217
1634
353
2813
1.37
5.45
7.4
5.5
—
—
—
0
0
455
3773
1.35
5.43
7.4
5.9
9.4
9.1
%
1.23
419
3500
83
487
1.76
5.33
5.4
2.8
0.7
0.6
%
0.88
83
470
278
2137
1.40
5.32
1.7
1.8
418.6
6775183.9
pmol/l
0.80
224
1727
412
3374
1.35
5.31
3.0
2.8
186.6
159.9
ug/l
0.93
368
3034
73
414
1.82
5.25
6.7
4.5
—
—
—
0
0
143
969
1.55
5.23
3.3
2.7
66.5
67.5
e9/l
0.13
116
764
483
4060
1.33
5.19
7.0
5.5
1.7
1.9
e9/l
1.32
436
3518
395
3231
1.34
5.08
3.8
3.2
1841.1
1859.4
ng/l
0.04
354
2811
57
303
1.93
5.01
8.2
5.3
1.7
1.4
mmol/l
0.82
51
262
53
275
1.97
5.00
2.9
3.1
0.9
0.8
nmol/l
0.52
36
209
82
491
1.72
4.92
4.9
4.6
—
—
—
0
0
134
913
1.53
4.78
2.8
2.6
3.8
6.0
ug/l
3.18
117
789
353
2865
1.34
4.72
4.1
3.5
72.2
83.1
e6/l
0.13
301
2294
263
2044
1.37
4.65
3.2
2.6
3.7
4.2
e6/l
0.39
235
1798
42
207
2.07
4.58
2.9
2.7
—
—
—
0
0
192
1422
1.42
4.49
2.8
2.6
2.2
2.2
g/l
0.39
172
1309
27
111
2.47
4.49
1.3
1.3
—
—
—
0
0
16
50
3.23
4.34
2.8
2.1
—
—
—
0
0
235
1815
1.37
4.29
5.7
4.2
1.0
1.0
kg/l
1.17
42
281
387
3218
1.31
4.28
4.7
3.9
67.7
130.7
e6/l
1.38
313
2430
299
2406
1.33
4.16
1.8
1.6
19.6
19.8
nmol/l
0.05
257
2014
40
202
2.02
4.11
8.6
2.7
—
—
—
0
0
69
415
1.71
4.11
7.4
4.3
0.8
0.9
%
0.81
64
387
88
565
1.60
4.08
3.5
2.7
0.6
0.4
e6/l
0.46
88
554
18
64
2.84
3.97
15.9
2.5
11.9
10.8
%
0.40
18
64
67
404
1.70
3.96
5.6
5.2
24.3
25.0
mmol/l
1.20
62
377
69
421
1.68
3.91
7.4
4.3
1.5
1.6
%
0.26
64
394
23
94
2.48
3.90
1.1
1.1
—
—
—
0
0
113
782
1.49
3.77
3.5
3.6
—
—
—
0
0
301
2459
1.31
3.71
3.8
3.4
—
—
—
0
0
249
1989
1.32
3.60
7.5
6.3
—
—
—
0
0
902
8467
1.33
3.55
31.3
20.5
139.5
139.6
mmol/l
0.89
884
8210
201
1560
1.35
3.53
2.8
2.6
12.3
12.0
umol/l
0.22
182
1430
178
1357
1.37
3.50
2.9
2.6
22.1
21.9
%
0.03
152
1148
97
663
1.51
3.45
2.0
2.2
353.3
369.2
nmol/l
0.41
87
596
278
2267
1.30
3.45
5.2
4.2
0.0
0.0
estimate
0.50
76
733
902
8479
1.32
3.43
31.2
20.6
4.0
4.0
mmol/l
0.32
883
8217
452
3919
1.26
3.40
2.4
2.1
88.9
92.1
pmol/l
0.81
276
2098
34
175
1.97
3.36
1.6
1.3
66.1
65.0
mmol/l
0.05
29
145
234
1875
1.31
3.29
4.9
3.8
—
—
—
0
0
30
149
2.04
3.27
1.2
1.2
—
—
—
0
0
32
163
1.99
3.26
10.3
2.3
64.2
62.0
%
0.19
32
163
47
272
1.76
3.26
11.2
13.7
—
—
—
0
0
464
4050
1.25
3.26
5.0
3.9
0.0
0.0
estimate
0.00
79
777
130
952
1.41
3.25
3.6
2.6
8.1
10.1
umol/l
1.09
117
844
178
2264
0.75
3.20
3.3
3.2
—
—
—
0
0
25
119
2.13
3.06
1.2
1.3
—
—
—
0
0
17
68
2.52
3.05
1.8
1.1
8.2
2.9
u/ml
0.56
11
27
100
707
1.45
3.03
3.5
3.9
109.4
99.8
ng/l
0.46
83
610
465
4085
1.24
3.01
5.1
3.9
0.0
0.0
estimate
0.50
78
756
309
2600
1.26
2.94
3.8
3.4
0.6
0.5
e6/l
0.36
257
2035
458
4026
1.23
2.93
6.8
5.3
0.0
0.0
estimate
0.00
83
773
685
6298
1.22
2.76
32.7
22.5
330.9
331.6
g/l
0.97
677
6230
77
529
1.49
2.72
1.8
1.9
1.5
1.5
g/l
0.18
63
462
8
19
4.23
2.68
12.4
15.7
1112.6
1443.7
nmol/l
—
8
19
8
19
4.23
2.68
8.4
12.6
624.8
833.6
nmol/l
—
8
19
34
192
1.79
2.60
1.7
1.6
—
—
—
0
0
59
387
1.55
2.59
1.3
1.4
—
—
—
0
0
15
62
2.44
2.54
2.5
1.2
—
—
—
0
0
21
101
2.10
2.54
1.0
1.1
—
—
—
0
0
91
657
1.42
2.50
1.5
1.5
—
—
—
0
0
86
615
1.43
2.49
1.5
1.5
—
—
—
0
0
18
82
2.21
2.48
2.3
1.2
—
—
—
0
0
80
565
1.45
2.48
3.1
2.9
11.5
10.9
g/l
0.42
74
516
11
39
2.84
2.48
2.2
1.3
—
—
—
0
0
37
218
1.72
2.47
10.2
5.6
106.8
105.1
mmol/l
1.37
32
193
37
218
1.72
2.47
10.2
5.6
11.0
11.5
mmol/l
0.46
32
193
8
21
3.83
2.46
1.1
1.5
—
—
—
0
0
38
228
1.69
2.39
1.8
2.3
129.4
127.7
g/l
0.16
32
169
116
881
1.35
2.37
3.0
2.7
65.7
65.9
g/l
0.11
105
789
18
84
2.16
2.35
1.9
1.2
—
—
—
0
0
655
6052
1.20
2.31
4.6
4.1
16.5
14.5
mm/h
1.78
602
5466
14
59
2.39
2.30
4.6
2.8
—
—
—
0
0
98
729
1.38
2.28
3.0
2.5
—
—
—
0
0
13
53
2.47
2.28
4.2
1.5
—
—
—
0
0
863
8191
1.23
2.27
24.2
16.5
—
—
—
0
0
21
106
2.00
2.26
1.0
1.2
246.0
294.2
u/ml
0.40
13
59
185
1509
1.27
2.26
3.4
3.2
2.0
1.9
e6/l
0.06
116
897
36
221
1.65
2.11
3.3
4.8
2.4
2.6
mmol/l
0.16
26
153
10
37
2.72
2.10
2.2
1.4
65.4
62.5
umol/l
—
5
24
5
10
5.02
2.07
1.0
1.1
—
—
—
0
0
20
103
1.96
2.06
2.5
2.0
—
—
—
0
0
122
955
1.31
2.05
6.1
4.6
—
—
—
0
0
21
111
1.91
2.01
1.2
1.2
—
—
—
0
0
42
272
1.57
2.00
3.4
4.4
7.4
7.4
ph
0.07
35
217
65
462
1.43
1.99
2.0
1.9
1.0
1.7
g/l
2.46
58
421
80
590
1.38
1.99
4.0
3.1
—
—
—
0
0
16
77
2.09
1.97
2.4
1.2
—
—
—
0
0
17
84
2.04
1.96
2.4
1.2
—
—
—
0
0
13
58
2.26
1.91
2.2
2.9
—
—
—
0
0
35
221
1.60
1.87
2.3
2.6
16.3
15.6
%
0.69
22
116
8
28
2.87
1.86
2.0
1.6
—
—
—
0
0
37
237
1.58
1.86
3.0
3.8
—
—
—
0
0
6
17
3.54
1.84
1.0
1.0
—
—
—
0
0
6
17
3.54
1.84
1.2
1.2
—
—
—
0
0
37
238
1.57
1.83
1.7
1.4
269.4
262.8
ug/g
0.07
20
143
30
186
1.63
1.73
3.4
3.9
1.7
1.6
%
0.07
15
142
109
862
1.29
1.73
1.3
1.3
408.0
461.2
titre
0.19
25
185
906
8718
1.20
1.67
37.3
24.9
7.1
6.9
e9/l
2.05
881
8372
877
8417
1.19
1.65
13.9
10.9
25.1
24.7
u/l
0.26
838
8004
905
8714
1.20
1.62
37.3
24.9
229.7
235.7
e9/l
1.76
880
8407
905
8715
1.20
1.62
37.1
24.8
30.5
30.5
pg
0.10
888
8509
905
8715
1.20
1.62
37.2
24.8
92.0
91.8
fl
0.49
888
8510
5
14
3.58
1.61
3.0
5.1
—
—
—
0
0
905
8716
1.20
1.61
37.3
24.9
4.3
4.4
e12/l
7.33
880
8374
16
84
1.92
1.60
2.4
1.2
—
—
—
0
0
13
63
2.08
1.60
1.1
1.0
177.8
312.0
ng/l
—
5
38
13
63
2.08
1.60
1.1
1.0
411.8
634.6
ng/l
—
5
37
905
8718
1.20
1.60
37.6
25.1
129.4
133.0
g/l
8.93
889
8509
6
21
2.87
1.50
1.2
1.6
—
—
—
0
0
64
481
1.35
1.48
3.0
2.9
—
—
—
0
0
7
28
2.51
1.45
2.3
2.8
—
—
—
0
0
6
22
2.74
1.43
2.3
2.2
—
—
—
0
0
53
712
0.73
1.43
1.5
1.5
—
—
—
0
0
24
149
1.62
1.42
2.5
2.5
—
—
—
0
0
5
17
2.95
1.36
1.4
1.0
1646.4
1307.2
miu/ml
—
5
17
205
1786
1.18
1.34
3.1
3.1
2.5
2.5
mmol/l
0.27
183
1548
16
271
0.58
1.33
1.4
1.4
—
—
—
0
0
48
353
1.38
1.29
4.3
3.5
48.2
74.2
mg/l
0.77
40
289
47
345
1.38
1.28
4.2
3.5
2.5
2.1
ratio
—
5
32
16
92
1.75
1.25
1.1
1.2
—
—
—
0
0
20
123
1.64
1.24
4.2
5.0
—
—
—
0
0
6
25
2.41
1.24
1.0
1.6
—
—
—
0
0
8
36
2.23
1.24
1.6
1.8
—
—
—
0
0
265
2372
1.15
1.23
3.8
2.9
374.5
7820.4
umol/l
9.52
219
1999
5
19
2.64
1.21
1.2
1.4
—
—
—
0
0
21
132
1.60
1.21
3.2
2.2
—
—
—
0
0
20
125
1.61
1.18
3.8
3.9
62.0
55.0
%
—
8
86
748
7175
1.13
1.12
4.8
4.4
2.1
2.1
mu/l
0.10
667
6333
17
104
1.64
1.09
2.4
1.2
—
—
—
0
0
5
21
2.39
1.09
6.8
2.4
—
—
—
0
0
94
778
1.23
1.09
1.6
1.6
—
—
—
0
0
41
304
1.36
1.08
1.9
2.1
37.6
37.1
g/l
0.21
31
254
7
32
2.19
1.08
1.0
1.0
—
—
—
0
0
7
33
2.13
1.05
1.4
1.6
—
—
—
0
0
35
254
1.39
1.05
4.0
3.5
—
—
—
0
0
12
67
1.80
1.05
1.3
1.2
—
—
—
0
0
5
22
2.28
1.03
5.8
2.5
—
—
—
0
0
35
258
1.37
0.98
1.9
2.4
129.9
95.1
ug/min
0.24
22
152
46
354
1.31
0.97
4.4
3.6
34.1
78.2
mg/l
0.71
39
294
183
1628
1.15
0.94
5.2
4.6
—
—
—
0
0
8
144
0.55
0.93
1.8
1.9
—
—
—
0
0
9
52
1.74
0.92
1.6
1.5
—
73.4
—
0
5
381
3554
1.11
0.90
13.3
10.4
0.0
0.0
e9/l
0.49
318
2889
617
5899
1.10
0.88
4.7
4.4
—
—
—
0
0
101
863
1.19
0.87
2.9
2.1
0.2
0.2
g/l
0.16
94
800
12
192
0.62
0.86
1.2
1.1
—
—
—
0
0
8
44
1.82
0.86
1.5
1.8
8.3
9.6
mmol/l
—
8
39
14
88
1.60
0.84
1.3
1.2
—
—
—
0
0
6
31
1.94
0.84
4.2
1.7
800.5
1733.5
u/ml
—
6
31
775
7505
1.11
0.83
6.8
6.5
41.7
41.0
mmol/mol
1.10
704
6775
40
311
1.30
0.82
4.8
4.8
—
—
—
0
0
15
97
1.55
0.81
1.0
1.1
—
—
—
0
0
13
81
1.61
0.81
1.3
1.3
—
—
—
0
0
32
242
1.33
0.79
1.4
1.5
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
—
—
0
0
8
48
1.67
0.79
2.3
1.5
—
—
—
0
0
0
27
0.00
0.77
0.0
1.1
—
1.5
—
0
20
22
157
1.41
0.77
1.5
1.3
14248.4
111415.8
e6/l
1.46
15
95
0
28
0.00
0.76
0.0
1.1
—
1.5
—
0
20
5
24
2.09
0.74
1.2
1.0
194.6
163.4
iu/ml
—
5
24
237
2181
1.11
0.73
4.8
3.7
—
—
—
0
0
7
39
1.80
0.72
1.1
1.3
0.2
0.2
nmol/l
—
7
26
7
40
1.75
0.71
1.1
1.1
—
—
—
0
0
5
26
1.93
0.70
2.0
1.5
—
—
—
0
0
5
26
1.93
0.70
2.6
1.7
—
—
—
0
0
48
391
1.24
0.70
1.3
1.2
—
—
—
0
0
7
41
1.71
0.70
3.7
3.4
—
—
—
0
0
320
2998
1.09
0.68
4.1
4.0
13.6
8.8
mg/mmol
0.95
230
1952
89
772
1.17
0.68
4.4
3.8
1.2
1.2
mmol/l
0.67
78
664
7
43
1.63
0.67
1.6
1.2
—
—
—
0
0
7
43
1.63
0.67
1.4
1.4
2.3
3.9
mmol/l
—
7
38
20
145
1.39
0.66
4.2
2.8
—
—
—
0
0
31
243
1.28
0.63
1.7
1.6
—
—
—
0
0
54
641
0.83
0.62
1.6
1.5
—
—
—
0
0
296
2778
1.09
0.61
5.8
4.4
—
—
—
0
0
96
1085
0.87
0.61
1.2
1.2
15.0
13.8
u/ml
0.06
30
377
23
174
1.33
0.60
1.6
1.4
743.2
1731.3
e6/l
2.50
18
127
0
21
0.00
0.60
0.0
1.1
—
20.6
—
0
16
0
21
0.00
0.60
0.0
1.4
—
5.2
—
0
9
0
21
0.00
0.60
0.0
1.4
—
—
—
0
0
747
7274
1.08
0.59
4.1
4.1
1.3
1.3
mmol/l
0.52
669
6397
44
364
1.22
0.58
2.8
3.1
4.3
4.4
pmol/l
0.16
38
312
8
54
1.48
0.57
2.8
3.2
—
—
—
0
0
18
132
1.37
0.57
1.1
1.5
—
—
—
0
0
10
149
0.67
0.57
1.6
1.7
—
—
—
0
0
17
229
0.74
0.56
1.2
1.4
—
—
—
0
0
6
37
1.62
0.55
1.0
1.0
—
—
—
0
0
6
37
1.62
0.55
4.2
3.5
—
—
—
0
0
125
1130
1.12
0.55
1.4
1.4
—
—
—
0
0
8
122
0.65
0.55
1.6
1.9
223.5
229.3
pmol/l
—
8
113
21
160
1.32
0.53
1.2
1.5
—
—
—
0
0
9
61
1.48
0.53
1.3
1.1
—
—
—
0
0
15
108
1.39
0.53
2.7
2.7
—
—
—
0
0
59
511
1.16
0.50
2.9
3.2
3.5
4.1
e9/l
1.30
39
373
107
966
1.12
0.50
3.4
3.1
336.7
249.0
ng/l
0.58
101
888
596
5782
1.07
0.49
4.0
3.6
15.1
15.1
pmol/l
0.02
535
5093
7
46
1.52
0.48
1.0
1.1
190.9
139.0
nmol/l
—
7
46
7
47
1.49
0.47
1.0
1.3
213.4
480.9
u/l
—
7
42
192
2055
0.92
0.47
1.7
1.6
1.4
1.3
mmol/l
0.47
155
1672
13
94
1.39
0.46
1.5
1.2
0.7
0.6
nmol/l
0.20
13
87
297
2827
1.07
0.43
3.3
3.3
269.4
239.5
mg/l
0.05
212
1862
24
193
1.25
0.43
1.3
1.2
—
752.0
—
0
5
12
87
1.38
0.42
1.6
1.2
—
—
—
0
0
12
87
1.38
0.42
1.7
1.6
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
301
2871
1.07
0.41
3.4
3.2
7.2
7.4
mmol/l
0.29
250
2355
8
58
1.38
0.41
1.5
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
11
149
0.74
0.40
3.6
3.1
4.4
4.5
e9/l
0.05
11
149
8
61
1.31
0.39
3.0
2.4
—
—
—
0
0
59
664
0.88
0.39
5.1
4.3
0.3
0.6
%
0.30
19
198
450
4357
1.05
0.37
5.5
5.7
8.5
4.5
ug/l
0.39
400
3824
27
225
1.20
0.37
1.5
1.5
—
—
—
0
0
106
1149
0.91
0.36
1.2
1.3
66.3
39.6
iu/ml
0.56
34
349
42
366
1.15
0.36
4.3
3.2
337.3
4548.5
u/ml
0.86
36
308
55
617
0.89
0.36
1.3
1.5
—
—
—
0
0
5
76
0.66
0.35
1.4
1.1
—
—
—
0
0
59
528
1.12
0.35
4.3
3.9
—
—
—
0
0
10
73
1.37
0.34
1.4
1.2
—
—
—
0
0
18
145
1.25
0.34
1.3
1.4
—
—
—
0
0
18
145
1.25
0.34
1.4
1.5
—
—
—
0
0
136
1274
1.08
0.33
1.6
1.5
3.0
2.7
g/l
0.67
82
726
6
47
1.28
0.32
2.3
3.7
105.7
115.3
nmol/l
—
6
47
6
47
1.28
0.32
1.0
1.4
—
—
—
0
0
18
146
1.24
0.32
1.2
1.6
—
—
—
0
0
83
763
1.09
0.31
1.4
1.4
—
—
—
0
0
49
438
1.12
0.30
1.3
1.3
—
—
—
0
0
12
152
0.79
0.29
3.7
3.5
60.0
59.2
%
0.11
12
152
10
130
0.77
0.29
1.4
1.3
—
—
—
0
0
55
497
1.11
0.29
1.2
1.2
—
—
—
0
0
22
186
1.19
0.28
1.0
1.1
—
—
—
0
0
17
141
1.21
0.26
1.4
1.5
2.6
6.4
iu/l
—
7
41
118
1112
1.07
0.26
1.3
1.3
—
—
—
0
0
37
330
1.13
0.25
1.1
1.2
93.4
147.2
iu/ml
0.65
15
114
28
319
0.87
0.25
1.5
1.4
—
—
—
0
0
9
75
1.20
0.25
1.0
1.1
—
—
—
0
0
12
148
0.81
0.24
1.0
1.1
—
—
—
0
0
26
297
0.87
0.24
1.2
1.2
—
—
—
0
0
5
38
1.32
0.23
1.2
1.4
1.0
1.0
g/l
—
5
38
338
3291
1.04
0.22
2.4
2.3
—
—
—
0
0
5
41
1.22
0.22
1.8
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
787
7783
1.04
0.21
5.1
5.1
6.2
6.1
mmol/l
0.67
694
6871
18
154
1.17
0.21
2.1
2.7
—
—
—
0
0
45
491
0.91
0.21
3.0
2.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
25
282
0.88
0.20
1.0
1.1
—
207.1
—
0
7
0
14
0.00
0.20
0.0
1.0
—
10.0
—
0
5
69
737
0.93
0.20
4.7
4.1
—
—
—
0
0
14
164
0.85
0.18
1.1
1.5
1.6
0.8
nmol/l
—
8
136
24
214
1.12
0.17
1.3
1.6
21310.0
19266.6
e6/l
0.09
14
151
7
62
1.13
0.17
1.3
1.2
—
—
—
0
0
18
205
0.88
0.17
1.4
1.2
—
—
—
0
0
13
110
1.18
0.17
1.2
2.0
—
—
—
0
0
8
72
1.11
0.16
1.4
1.2
—
—
—
0
0
92
880
1.05
0.15
1.4
1.3
—
—
—
0
0
643
6361
1.03
0.15
30.4
20.5
14.2
13.9
%
3.96
635
6202
39
362
1.08
0.14
2.7
3.3
0.3
0.3
g/l
0.03
12
143
696
6900
1.02
0.12
27.9
18.2
38.1
38.7
%
0.67
393
4158
15
133
1.13
0.12
1.5
1.4
—
—
—
0
0
768
7629
1.02
0.11
4.6
4.6
4.2
4.4
mmol/l
8.61
695
6834
29
270
1.08
0.10
5.5
3.8
—
—
—
0
0
15
166
0.90
0.09
1.7
1.7
45.6
42.2
nmol/l
0.34
15
156
76
733
1.04
0.09
2.3
2.2
136.1
156.6
ug/g
0.29
56
564
5
61
0.82
0.08
4.4
1.8
—
—
—
0
0
73
754
0.97
0.08
4.9
4.2
1.4
0.8
%
0.80
28
252
10
88
1.14
0.08
1.1
1.7
—
—
—
0
0
10
88
1.14
0.08
1.7
1.2
—
—
nmol/l
—
0
0
789
7852
1.02
0.08
5.1
5.2
2.4
2.6
mmol/l
8.07
706
6991
7
84
0.83
0.07
1.7
1.5
—
—
—
0
0
7
84
0.83
0.07
1.3
1.3
—
—
—
0
0
12
132
0.91
0.06
1.4
1.4
7.1
6.3
mmol/l
0.47
12
124
108
1058
1.02
0.06
4.2
4.0
54.5
33.1
ug/l
0.25
95
896
99
969
1.02
0.06
1.4
1.4
—
—
—
0
0
23
218
1.06
0.05
3.1
3.5
28.2
30.5
mg/l
0.10
17
140
69
706
0.98
0.04
4.8
4.3
0.1
0.1
%
0.18
27
231
14
130
1.08
0.04
1.3
1.2
—
—
—
0
0
22
209
1.05
0.04
1.3
1.1
—
—
—
0
0
139
1408
0.99
0.04
1.2
1.2
0.8
1.2
u/ml
0.85
33
338
21
203
1.04
0.01
2.2
2.2
—
—
—
0
0
66
668
0.99
0.01
2.2
2.2
12.6
12.0
nmol/l
0.17
58
571
68
673
1.01
0.01
4.5
4.1
1.2
0.5
%
0.56
19
186
10
96
1.04
0.00
1.4
1.4
84.6
68.5
%
—
5
70
11
106
1.04
0.00
1.2
1.6
—
—
—
0
0
11
106
1.04
0.00
1.2
1.6
—
—
—
0
0
11
106
1.04
0.00
1.2
1.6
—
—
—
0
0
11
106
1.04
0.00
1.2
1.6
—
—
—
0
0
13
126
1.03
0.00
1.4
1.5
—
—
—
0
0
37
371
1.00
0.00
1.1
1.3
—
—
—
0
0
247
2471
1.00
0.00
3.4
3.4
1.2
0.8
ug/l
1.24
171
1775
12
117
1.03
0.00
3.1
2.3
3.2
381.5
u/ml
0.56
12
112
36
363
0.99
0.00
2.0
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
2.0
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
1.3
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
0.1
—
0
9
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
8
89
0.90
0.00
3.1
3.2
—
—
—
0
0
5
58
0.86
0.00
1.4
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
753
7530
1.00
0.00
4.6
4.6
1.3
1.4
mmol/l
6.36
672
6681
5
49
1.02
0.00
3.4
3.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
67
0.89
0.00
1.8
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
6.7
—
—
—
0
0
6
60
1.00
0.00
3.0
2.2
479.5
501.8
min
—
6
39
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
8.7
—
35.0
—
0
6

Mortality – FinRegistry

Association

Association between endpoint I9_OTHINTRACRA and mortality.

Females

Parameter HR [95% CI] p-value
I9_OTHINTRACRA 2.148 [1.85, 2.49] < 0.001
Birth year 0.996 [0.99, 1.0] 0.346

During the follow-up period (1.1.1998 — 31.12.2019), 1445 out of 2816 females with I9_OTHINTRACRA died.

Males

Parameter HR [95% CI] p-value
I9_OTHINTRACRA 2.024 [1.74, 2.35] < 0.001
Birth year 0.986 [0.98, 1.0] 0.003

During the follow-up period (1.1.1998 — 31.12.2019), 2569 out of 4843 males with I9_OTHINTRACRA died.

Mortality risk

Mortality risk for people of age

years, who have I9_OTHINTRACRA.

N-year risk Females Males
1 0.205% 0.342%
5 1.286% 2.021%
10 3.13% 5.194%
15 6.112% 10.143%
20 10.484% 17.079%

Relationships between endpoints

Index endpoint: I9_OTHINTRACRA – Other intracranial haemorrhages

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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