Adrenogenital disorders

E4_ADRENOGEN

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E25
  • Hospital discharge: ICD-9 2552
  • Hospital discharge: ICD-8 2550[1-2]
  • Cause of death: ICD-10 E25
  • Cause of death: ICD-9 2552
  • Cause of death: ICD-8 2550[1-2]

2 out of 7 registries used, show all original rules.

165

4. Check minimum number of events

None

165

5. Include endpoints

None

165

6. Filter based on genotype QC (FinnGen only)

165

Control definitions (FinnGen only)

Control exclude
E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E20-E35
Name in latin
Perturbationes adrenogenitales

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1321 789 518
Only index persons 1074 671 403
Unadjusted period prevalence (%)
Whole population 0.02 0.02 0.01
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 53.68 48.68 61.35
Only index persons 49.85 44.47 58.80

-FinnGen-

Key figures

All Female Male
Number of individuals 165 101 64
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 50.92 45.35 59.71

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
148
Matched controls
1479
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E25.9
ICD-10 Finland
Adrenogenital disorder, unspecified
+∞
68.1
60
*
E25.00
ICD-10 Finland
Congenital salt-losing adrenal hyperplasia
+∞
42.8
39
*
E25.01
ICD-10 Finland
Congenital adrenal hyperplasia
+∞
41.6
38
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
26.9
25
*
H02AB09
ATC
hydrocortisone; systemic
44.6
21.6
26
7
E25.8
ICD-10 Finland
Other adrenogenital disorders
+∞
19.2
18
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
34.6
16.6
21
7
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
11.6
16.4
31
33
H02AA02
ATC
fludrocortisone; oral
36.0
15.2
19
6
A11CC03
ATC
alfacalcidol; systemic
24.2
15.2
21
10
E25.0
ICD-10 Finland
Congenital adrenogenital disorders associated with enzyme deficiency
+∞
13.8
13
*
E21.09
ICD-10 Finland
Other primary hyperparathyroidism
153.5
13.7
14
*
A12AA04
ATC
calcium carbonate; oral
44.4
13.4
16
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
11.6
11
*
25502
ICD-8 Finland
Diseases of adrenal glands, Virilismus adrenocorticalis
+∞
10.5
10
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
4.9
10.1
34
84
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
3.7
9.0
43
147
E27.4
ICD-10 Finland
Other and unspecified adrenocortical insufficiency
+∞
8.4
8
*
2552A
ICD-9 Finland
Disorders of adrenal glands, Adrenogenital disorders[SYNDROMA ADRENOGENITALE CONGENITUM]
+∞
8.4
8
*
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.3
8.1
47
184
Z49.1
ICD-10 Finland
Extracorporeal dialysis
47.5
7.8
9
*
TK800
NOMESCO Finland
Hemodialysis
19.6
7.7
11
6
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.1
7.6
20
37
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
7.5
53
238
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
16.8
7.3
11
7
321
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
7.3
7
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.2
7.3
43
170
V03AE01
ATC
polystyrene sulfonate; oral
31.7
7.2
9
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
7.0
33
110
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.2
7.0
39
148
N03AX16
ATC
pregabalin; oral
3.1
6.9
41
161
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
17.7
6.8
10
6
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
4.9
6.7
21
48
N18.8
ICD-10 Finland
Other chronic renal failure
10.8
6.7
12
12
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
10.8
6.7
12
12
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
6.5
6.5
16
27
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
6.5
29
93
R53
ICD-10 Finland
Malaise and fatigue
2.8
6.4
45
198
127
Kela drug reimbursment
Transplant complication
28.0
6.3
8
*
L04AA06
ATC
mycophenolic acid; systemic
28.0
6.3
8
*
E21.3
ICD-10 Finland
Hyperparathyroidism, unspecified
+∞
6.3
6
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3035637) Corticotropin [Mass/volume] in Plasma
24
11
25.36
32.78
3.3
1.5
—
—
—
0
0
(3023530) 17-Hydroxyprogesterone [Moles/volume] in Serum or Plasma
21
0
+∞
22.40
8.3
0.0
nmol/l
68.8
—
—
21
0
(3018418) pH of Serum or Plasma
85
359
3.82
16.29
9.3
3.9
ph
7.4
7.4
0.01
23
63
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
37
89
5.07
15.07
6.8
3.7
ng/l
162.0
76.3
1.86
28
77
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
107
591
3.31
12.30
15.9
6.2
mmol/l
1.2
1.2
0.62
86
497
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
103
566
3.18
11.76
12.7
5.0
mmol/l
1.2
1.2
0.34
97
501
(3009214) Lutropin [Units/volume] in Serum or Plasma
18
34
5.82
9.39
2.6
1.2
u/l
7.6
7.2
0.05
11
29
(3052851) Hemolysis interference index of Serum or Plasma
19
38
5.52
9.34
3.3
2.5
—
—
—
0
0
(3026782) Osmolality of Urine
53
261
2.52
6.63
4.1
2.8
mosm/kgh2o
506.1
547.8
0.80
45
224
(36304419) Bacteria [Presence] in Urine
64
350
2.35
6.32
4.6
2.8
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
21
67
3.45
5.70
1.9
1.7
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
74
451
2.16
5.46
5.4
3.2
—
—
—
0
0
(40760888) Immunoglobulin light chains.free panel - Serum
11
22
5.29
5.34
5.7
8.7
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
46
235
2.33
5.18
1.8
1.7
nmol/l
1056.2
1174.1
0.28
41
170
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
31
133
2.64
5.05
2.4
1.8
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
41
205
2.33
4.82
2.7
1.9
—
—
—
0
0
(3012544) pH of Venous blood
28
118
2.65
4.71
5.3
3.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
30
131
2.58
4.71
2.3
1.7
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
60
355
2.08
4.64
5.2
2.9
e6/l
0.3
0.5
0.71
48
255
(3002582) Erythrocytes [#/volume] in Urine
65
401
2.02
4.45
5.1
3.1
e6/l
37.1
224.2
0.58
51
298
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
10
22
4.77
4.36
2.7
2.5
u/ml
0.3
0.4
—
5
12
(3004588) Protein electrophoresis panel - Serum or Plasma
20
77
2.82
3.98
4.4
3.4
—
—
—
0
0
(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells
11
29
3.99
3.87
1.5
2.1
—
—
—
0
0
(3000991) Gas panel - Venous blood
23
97
2.59
3.85
11.6
6.1
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
66
427
1.91
3.83
8.3
5.4
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
70
465
1.88
3.73
15.6
8.8
inr
1.2
1.2
0.00
23
139
(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma
23
104
2.41
3.34
3.2
2.8
u/l
24.7
29.5
0.72
18
90
(3018095) Leukocytes [#/volume] in Urine
69
472
1.79
3.25
5.6
3.8
e6/l
78.9
79.3
0.00
52
315
(3021589) Normoblasts [#/volume] in Blood
79
569
1.75
3.07
16.8
9.4
e9/l
0.0
0.0
0.49
65
457
(3022096) Basophils/100 leukocytes in Blood
78
560
1.75
3.07
8.6
6.0
%
0.7
0.6
0.20
73
519
(3020682) Albumin/Creatinine [Ratio] in Urine
51
323
1.84
3.06
5.6
4.0
mg/mmol
25.3
11.5
0.87
38
207
(3023368) Bacteria identified in Blood by Culture
54
349
1.81
3.03
8.7
4.2
—
—
—
0
0
(3018010) Neutrophils/100 leukocytes in Blood
80
582
1.73
2.98
8.5
5.7
%
58.0
57.8
0.06
75
543
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
8
17
4.89
2.96
9.1
2.5
—
—
—
0
0
(3012516) Albumin [Mass/volume] in Urine
48
303
1.82
2.90
5.0
3.1
mg/l
1541.5
61.3
0.51
37
191
(3006504) Eosinophils/100 leukocytes in Blood
79
576
1.71
2.90
8.6
5.8
%
2.7
2.6
0.08
74
535
(3013826) Glucose [Moles/volume] in Serum or Plasma
94
721
1.71
2.84
7.7
4.2
mmol/l
7.2
6.5
1.54
89
663
(3022806) Fractional oxyhemoglobin in Capillary blood
8
18
4.61
2.83
3.5
1.6
%
88.3
89.3
—
8
18
(3019069) Monocytes/100 leukocytes in Blood
79
579
1.70
2.82
8.7
6.1
%
8.5
8.6
0.13
74
541
(3027945) Reticulocytes/100 erythrocytes in Blood
27
141
2.09
2.81
2.7
2.9
%
1.8
1.7
0.39
27
121
(3009508) Creatinine [Moles/volume] in Urine
53
348
1.77
2.80
5.1
3.0
mmol/l
6.9
7.5
0.40
48
291
(3002030) Lymphocytes/100 leukocytes in Blood
80
591
1.69
2.76
8.7
5.9
%
27.2
27.8
0.18
75
551
(3002256) Pathology report gross observation
26
135
2.10
2.74
1.2
1.2
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
10
32
3.26
2.69
1.2
1.5
—
—
—
0
0
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
67
476
1.69
2.65
2.6
2.0
pmol/l
90.9
94.7
0.30
38
239
(3018677) aPTT in Platelet poor plasma by Coagulation assay
31
176
1.94
2.57
2.0
2.0
s
29.6
29.6
0.01
31
170
(3017817) Protein [Mass] in Urine collected for unspecified duration
5
7
7.32
2.56
4.4
6.0
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
83
628
1.65
2.55
8.2
5.7
e9/l
0.6
0.6
0.13
70
545
(3006315) Basophils [#/volume] in Blood
83
629
1.64
2.53
8.2
5.7
e9/l
0.0
0.0
0.11
70
547
(3019198) Lymphocytes [#/volume] in Blood
84
643
1.62
2.43
9.1
5.7
e9/l
1.9
1.8
0.09
74
574
(3013115) Eosinophils [#/volume] in Blood
84
646
1.61
2.36
9.5
6.0
e9/l
0.2
0.2
0.32
73
573
(3026008) Bacteria identified in Urine by Culture
58
410
1.64
2.28
4.0
3.4
—
—
—
0
0
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
36
224
1.78
2.24
6.2
3.2
ng/l
36.8
107.1
1.05
29
172
(3013650) Neutrophils [#/volume] in Blood by Automated count
92
737
1.56
2.09
12.1
9.4
e9/l
4.2
4.1
0.05
79
645
(21494890) Protein electrophoresis panel - 24 hour Urine
5
10
5.12
2.08
5.2
4.8
—
—
—
0
0
(3021788) Differential panel - Synovial fluid
5
10
5.12
2.08
1.4
2.1
—
—
—
0
0
(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma
84
660
1.56
2.07
7.0
5.7
umol/l
9.8
10.2
0.25
84
619
(3049717) Cytology report of Urine Cyto stain
11
44
2.61
2.06
1.9
2.5
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
25
143
1.88
2.03
2.2
1.6
—
—
—
0
0
(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection
5
11
4.65
1.95
1.0
1.3
—
—
—
0
0
(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection
7
22
3.28
1.90
1.6
1.5
—
—
—
0
0
(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection
6
17
3.62
1.85
1.7
1.4
—
—
—
0
0
(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection
6
17
3.62
1.85
1.7
1.5
—
—
—
0
0
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
40
270
1.64
1.85
1.8
1.8
mg/l
0.8
1.4
0.89
32
209
(3050238) Crystals [Presence] in Synovial fluid by Light microscopy
7
23
3.13
1.82
1.4
1.5
—
—
—
0
0
(3030905) Polymorphonuclear cells [#/volume] in Blood
7
23
3.13
1.82
2.3
2.1
e9/l
4.0
4.5
—
7
23
(3032035) Polymorphonuclear cells/100 leukocytes in Blood
7
23
3.13
1.82
2.3
2.8
%
61.6
59.5
—
7
23
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
11
47
2.44
1.82
6.5
3.0
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
20
112
1.89
1.74
5.6
3.8
—
—
—
0
0
(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay
6
19
3.24
1.67
1.0
1.1
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
25
154
1.73
1.62
2.3
1.7
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
28
179
1.68
1.59
2.5
1.9
—
—
—
0
0
(40758558) Short blood count panel - Blood
45
326
1.52
1.54
7.0
6.9
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
5
15
3.40
1.53
1.6
1.7
pg
29.0
32.1
—
5
15
(3037756) Immunofixation for Serum or Plasma
7
27
2.66
1.53
1.4
1.8
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
31
207
1.61
1.49
4.5
2.7
e6/l
0.9
0.9
0.06
14
106
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
7
28
2.56
1.47
1.9
1.2
—
19.3
—
0
5
(3021879) Hepatitis B virus core Ab [Presence] in Serum
17
96
1.86
1.45
1.7
1.6
—
—
—
0
0
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
6
22
2.79
1.45
1.7
1.2
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
30
202
1.59
1.40
4.6
3.0
e6/l
5.1
3.4
0.28
13
103
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
14
75
1.95
1.39
2.1
1.2
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
102
879
1.42
1.36
7.0
4.6
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
21
130
1.71
1.34
5.5
3.4
—
—
—
0
0
(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection
0
40
0.00
1.34
0.0
1.4
—
—
—
0
0
(3044290) Cell count panel - Cerebral spinal fluid
6
24
2.55
1.31
1.0
1.3
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
106
923
1.42
1.31
5.4
3.9
mm/h
15.3
11.7
1.41
101
825
(3015377) Calcium [Moles/volume] in Serum or Plasma
57
446
1.42
1.31
6.5
3.4
mmol/l
2.3
2.4
0.67
52
386
(3009445) Proteinase 3 Ab [Units/volume] in Serum
10
48
2.15
1.30
1.7
1.2
—
—
—
0
0
(3014148) Varicella zoster virus Ab [Titer] in Serum
5
18
2.83
1.29
1.0
1.2
—
—
—
0
0
(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability
5
18
2.83
1.29
1.2
1.4
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
24
159
1.60
1.20
1.2
1.2
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
11
57
2.00
1.20
16.9
6.6
—
—
—
0
0
(40768443) Skin Pathology biopsy report
9
46
2.01
1.05
1.9
1.1
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
15
91
1.71
1.04
2.2
1.6
—
—
—
0
0
(3023024) Carbon dioxide [Partial pressure] in Capillary blood
15
91
1.71
1.04
8.9
4.0
kpa
5.1
5.1
0.12
15
82
(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay
5
22
2.31
1.04
1.8
1.2
—
—
—
0
0
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
48
379
1.38
1.02
3.8
2.2
u/l
56.0
56.0
0.00
43
350
(3019060) Gas panel - Arterial blood
13
76
1.77
1.02
5.8
3.7
—
—
—
0
0
(3022313) Gas panel - Capillary blood
11
61
1.86
1.01
10.5
4.6
—
—
—
0
0
(3005033) Fetal Nuchal fold Thickness US
0
30
0.00
0.98
0.0
1.5
—
—
—
0
0
(3047352) Trisomy 18 risk [Likelihood] in Fetus
0
30
0.00
0.98
0.0
1.5
—
—
—
0
0
(3043238) Trisomy 21 risk [Likelihood] in Fetus
0
32
0.00
0.96
0.0
1.6
—
—
—
0
0
(3044889) 12 lead EKG panel
95
839
1.31
0.93
4.7
3.8
—
—
—
0
0
(1616796) Gas panel - Central venous blood
6
28
2.18
0.92
11.3
2.8
—
—
—
0
0
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
6
30
2.04
0.88
2.0
1.3
—
—
—
0
0
(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection
6
31
1.97
0.85
2.2
1.6
—
—
—
0
0
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
6
31
1.97
0.85
1.3
1.1
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
12
73
1.69
0.84
1.0
1.0
—
—
—
0
0
(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection
6
33
1.85
0.80
2.2
1.6
—
—
—
0
0
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
25
0.00
0.79
0.0
1.1
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
27
203
1.39
0.77
1.4
1.3
iu/ml
31.9
38.7
—
6
59
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
125
1163
1.31
0.74
23.0
13.0
ml/min/173m2
76.3
82.6
1.47
108
934
(40760892) CBC W Ordered Manual Differential panel - Blood
34
268
1.34
0.73
7.1
5.1
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
15
101
1.53
0.73
12.1
5.1
mmol/l
1.1
1.3
0.50
15
96
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
11
168
0.63
0.72
1.6
2.3
—
—
—
0
0
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
25
191
1.36
0.66
1.2
1.3
u/ml
1.3
10.9
—
9
71
(3021601) Nitrite [Presence] in Urine by Test strip
72
635
1.24
0.65
6.3
5.2
estimate
0.0
0.0
0.00
21
120
(44816559) Phosphatidylethanol [Mass/volume] in Blood
5
30
1.69
0.62
1.4
1.2
—
—
—
0
0
(3003740) Influenza virus B Ag [Presence] in Specimen
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
(3002523) Influenza virus A Ag [Presence] in Specimen
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
105
970
1.23
0.58
5.0
3.9
pmol/l
14.9
14.8
0.28
100
857
(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection
6
37
1.64
0.56
3.0
2.0
—
—
—
0
0
(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)
12
82
1.50
0.56
1.9
2.4
ml/min/173m2
76.3
65.1
—
7
31
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
13
180
0.70
0.55
1.7
2.4
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
41
347
1.24
0.53
3.9
4.3
estimate
0.0
0.0
0.00
20
114
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
52
452
1.22
0.52
6.8
3.9
ng/l
37.3
48.6
0.42
41
309
(3000492) Spirometry study
14
103
1.39
0.47
1.4
1.4
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
19
148
1.32
0.46
1.4
1.4
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
70
635
1.18
0.44
4.5
3.9
estimate
0.0
0.0
0.00
22
120
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
5
31
1.63
0.43
1.4
1.3
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
8
56
1.45
0.43
3.0
2.4
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
11
79
1.42
0.42
1.3
1.9
—
—
—
0
0
(3014133) Dog dander IgE Ab [Units/volume] in Serum
0
15
0.00
0.41
0.0
1.0
—
1.6
—
0
6
(3009041) Cardiolipin IgG Ab [Units/volume] in Serum by Immunoassay
0
15
0.00
0.41
0.0
1.1
—
2.9
—
0
8
(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
(3016701) Glucose [Moles/volume] in Serum or Plasma --2 hours post dose glucose
0
16
0.00
0.41
0.0
1.3
—
7.3
—
0
9
(40768806) Pleura Pathology biopsy report
0
17
0.00
0.41
0.0
2.0
—
—
—
0
0
(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection
0
17
0.00
0.41
0.0
2.0
—
—
—
0
0
(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection
0
17
0.00
0.41
0.0
2.0
—
—
—
0
0
(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection
0
17
0.00
0.41
0.0
2.0
—
—
—
0
0
(3024891) Influenza virus A+B Ag [Presence] in Specimen
5
34
1.48
0.40
1.2
1.2
—
—
—
0
0
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
13
98
1.35
0.39
1.3
2.1
—
—
—
0
0
(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum
5
36
1.40
0.38
1.6
1.3
—
—
—
0
0
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
89
830
1.16
0.38
3.6
2.9
u/l
45.5
43.5
0.15
82
774
(3009261) Glucose [Presence] in Urine by Test strip
70
642
1.16
0.37
4.5
4.0
estimate
0.0
0.0
0.00
22
113
(3041096) Erythrocytes [Presence] in Urine by Automated
40
351
1.18
0.36
5.0
3.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
91
853
1.15
0.35
3.5
3.3
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
137
1324
1.20
0.35
24.6
12.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
15
118
1.30
0.35
1.1
1.1
—
—
—
0
0
(40761535) Cells panel - Urine sediment
13
101
1.31
0.33
4.5
3.8
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
34
298
1.18
0.32
2.8
4.0
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
7
52
1.36
0.31
3.4
2.1
—
—
—
0
0
(4010399)
12
93
1.31
0.31
1.4
1.4
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
37
414
0.86
0.29
3.1
2.8
—
—
—
0
0
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
35
311
1.16
0.28
1.5
1.2
u/ml
1.4
1.1
—
8
77
(3044640) Blood type and Crossmatch panel - Blood
44
398
1.14
0.28
3.1
2.1
—
—
—
0
0
(3019225) pH of Specimen
14
113
1.26
0.27
18.0
4.6
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
12
149
0.79
0.27
1.7
1.5
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
10
77
1.32
0.27
1.9
1.8
g/l
1.1
1.6
—
10
70
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
31
275
1.16
0.25
1.7
1.6
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
9
75
1.21
0.25
1.1
1.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
12
147
0.80
0.24
13.3
7.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
30
336
0.87
0.24
1.4
1.4
—
—
—
0
0
(3015235) Bicarbonate [Moles/volume] in Capillary blood
5
37
1.36
0.24
3.0
2.6
mmol/l
26.2
24.1
—
5
30
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
38
1.33
0.23
1.6
1.2
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
124
1203
1.12
0.22
5.1
4.2
mmol/l
4.4
4.6
1.67
118
1106
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
24
211
1.16
0.22
2.7
1.7
—
—
—
0
0
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
5
41
1.23
0.22
1.4
1.6
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
8
103
0.77
0.22
1.6
1.6
—
—
—
0
0
(4268621)
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
(3036428) Adenosine deaminase [Enzymatic activity/volume] in Pleural fluid
0
11
0.00
0.21
0.0
1.3
—
10.1
—
0
11
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose
0
11
0.00
0.21
0.0
1.7
—
6.9
—
0
5
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
11
0.00
0.21
0.0
2.3
—
—
—
0
0
(3000012) Reticulocyte production index
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
10
0.00
0.21
0.0
2.3
—
—
—
0
0
(3022756) Ceruloplasmin [Mass/volume] in Serum or Plasma
0
10
0.00
0.21
0.0
1.1
—
285.3
—
0
10
(4306422)
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(4024509)
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
1.0
—
1.5
—
0
5
(3044355) Beta 2 glycoprotein 1 IgG Ab [Units/volume] in Serum or Plasma by Immunoassay
0
13
0.00
0.21
0.0
1.2
—
1.2
—
0
5
(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
(3019897) Erythrocyte distribution width [Ratio] by Automated count
0
13
0.00
0.21
0.0
1.7
—
13.6
—
0
13
(3023430) Cat dander IgE Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.0
—
1.1
—
0
5
(40763082) Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Lactate to pyruvate reaction
0
14
0.00
0.20
0.0
1.4
—
203.9
—
0
14
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
(3003327) Ova and parasites identified in Stool by Light microscopy
6
50
1.21
0.20
1.0
1.6
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
6
50
1.21
0.20
2.0
1.8
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
31
281
1.13
0.19
1.6
1.5
g/l
2.4
2.5
0.12
18
158
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
130
1269
1.12
0.19
27.0
13.9
mg/l
24.5
24.0
0.06
111
1008
(3009542) Hematocrit [Volume Fraction] of Blood
118
1148
1.10
0.17
26.7
14.2
%
39.7
39.8
0.07
85
850
(3019150) Specific gravity of Urine by Refractometry
27
297
0.89
0.17
4.4
4.1
kg/l
1.0
1.0
—
6
39
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
126
1232
1.10
0.15
5.7
4.7
mmol/l
2.6
2.7
1.16
120
1118
(3013512) EKG study
39
364
1.09
0.15
5.0
3.9
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
52
492
1.08
0.15
4.9
4.0
—
—
—
0
0
(4035726)
12
105
1.15
0.11
1.8
1.4
—
—
—
0
0
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
122
1198
1.07
0.11
5.1
4.2
mmol/l
1.4
1.5
0.44
115
1090
(1002224) Polysomnography panel
5
43
1.17
0.10
1.0
1.1
—
—
—
0
0
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
5
45
1.11
0.10
1.0
1.2
—
—
—
0
0
(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay
5
47
1.07
0.09
1.4
1.1
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
5
47
1.07
0.09
3.6
1.5
mg/l
2.5
3.0
—
5
30
(1001926) Buprenorphine [Presence] in Urine by Screen method
5
47
1.07
0.09
3.2
1.6
—
—
—
0
0
(3008898) HLA-B27 [Presence]
6
54
1.12
0.09
1.0
1.1
—
—
—
0
0
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
31
293
1.07
0.08
3.3
2.1
—
—
—
0
0
(3016879) Cocaine [Presence] in Urine
6
58
1.04
0.08
6.3
1.5
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
14
154
0.90
0.08
1.4
1.8
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
5
60
0.83
0.08
9.4
3.7
—
—
—
0
0
(3022621) pH of Urine by Test strip
9
85
1.06
0.07
2.8
3.2
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
59
575
1.04
0.05
5.7
3.8
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
24
228
1.06
0.05
3.1
4.5
%
27.0
21.3
0.68
12
118
(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma
31
299
1.05
0.04
3.6
4.9
ug/l
1.8
2.4
0.60
26
259
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
21
200
1.06
0.04
1.8
1.4
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
50
490
1.03
0.03
2.0
1.9
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
116
1150
1.03
0.03
4.7
3.8
mmol/l
1.4
1.2
2.25
110
1046
(46235355) HIV 1 and 2 tests - Meaningful Use set
26
267
0.97
0.01
2.6
2.0
—
—
—
0
0
(3048689) Calprotectin [Mass/mass] in Stool
17
171
0.99
0.00
1.5
2.0
ug/g
93.0
102.7
0.09
12
134
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
119
1186
1.01
0.00
6.5
4.4
mmol/l
6.0
5.8
0.56
114
1068
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
12
123
0.97
0.00
1.4
1.8
—
—
—
0
0
(3022145) Colonoscopy Study observation
14
138
1.02
0.00
1.0
1.3
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
15
152
0.99
0.00
5.9
4.5
%
35.9
31.2
1.18
15
92
(3022689) Creatine [Moles/volume] in Urine
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3004446) Plasmodium sp identified in Blood by Light microscopy
0
5
0.00
0.00
0.0
3.0
—
—
—
0
0
(3028772) Osteocalcin [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3011544) Albumin [Mass/volume] in Pleural fluid
0
5
0.00
0.00
0.0
1.0
—
17.1
—
0
5
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
2.4
—
—
—
0
0
(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
4.2
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
75
0.93
0.00
1.0
1.2
—
—
—
0
0
(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay
0
9
0.00
0.00
0.0
1.2
—
100.4
—
0
9
(3006653) Thiamine [Moles/volume] in Blood
0
6
0.00
0.00
0.0
1.0
—
110.8
—
0
6
(3035933) Granulocytes/100 leukocytes in Blood
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002619) Bacteria identified in Specimen by Culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
2.3
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
(3011363) Streptococcus pneumoniae Ag [Presence] in Urine
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3022058) Hepatitis B virus DNA [Presence] in Serum or Plasma by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
85.7
—
0
6
(44806420)
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
6
0.00
0.00
0.0
1.5
—
38.5
—
0
6
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3044242) Glucose [Moles/volume] in Arterial blood
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(3016724) Homocysteine [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.0
—
20.8
—
0
6
(3004716) Salmonella sp identified in Stool by Organism specific culture
7
70
1.00
0.00
1.0
1.3
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
6
63
0.95
0.00
6.3
1.5
—
—
—
0
0
(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
6
63
0.95
0.00
6.3
1.4
—
—
—
0
0
(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
6
63
0.95
0.00
6.3
1.4
—
—
—
0
0
(42870308) Desmosome IgG Ab [Titer] in Serum by Immunofluorescence
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
58
0.86
0.00
2.6
2.2
—
—
—
0
0
(40765096) Chromosome analysis panel by Banding
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(40758292) HTLV I+II Ab panel - Serum
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3027231) Wheat IgE Ab [Units/volume] in Serum
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3035880) pH of Pleural fluid
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3007821) Glucose [Moles/volume] in Serum or Plasma --baseline
0
5
0.00
0.00
0.0
1.0
—
6.2
—
0
5
(3037692) Legionella sp identified in Specimen by Organism specific culture
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
(44816893) Food Allergen Mix 50 (Kiwi+Pineapple+Banana+Mango) IgE Ab [Units/volume] in Serum by Multidisk
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3042299) inFLIXimab [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
8.1
—
5.8
—
0
7
(3015183) Erythrocyte sedimentation rate
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
6
63
0.95
0.00
6.3
1.4
—
—
—
0
0
(3020650) Glucose [Presence] in Urine
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3020491) Glucose [Moles/volume] in Blood
0
6
0.00
0.00
0.0
1.2
—
6.1
—
0
6
(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3017569) Oxygen content in Arterial blood
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
0
9
0.00
0.00
0.0
2.4
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
3.0
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
7
0.00
0.00
0.0
2.9
—
—
—
0
0
(4211845)
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_ADRENOGEN and mortality.

Females

Parameter HR [95% CI] p-value
E4_ADRENOGEN 2.292 [1.79, 2.93] < 0.001
Birth year 0.995 [0.99, 1.0] 0.259

During the follow-up period (1.1.1998 — 31.12.2019), 185 out of 572 females with E4_ADRENOGEN died.

Males

Parameter HR [95% CI] p-value
E4_ADRENOGEN 2.783 [1.92, 4.04] < 0.001
Birth year 0.984 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 182 out of 401 males with E4_ADRENOGEN died.

Mortality risk

Mortality risk for people of age

years, who have E4_ADRENOGEN.

N-year risk Females Males
1 0.204% 0.453%
5 1.287% 2.978%
10 3.461% 7.181%
15 6.431% 13.75%
20 11.168% 22.495%

Relationships between endpoints

Index endpoint: E4_ADRENOGEN – Adrenogenital disorders

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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