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Esophageal diverticulum (pouch)

Endpoint Browser

Q17_ESOPHAGEAL_DIVERTICULUM_WIDE

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 — Q39.6
  • Hospital discharge: ICD-10 — Q39.6
  • Cause of death: ICD-10 — Q39.6

3 out of 7 registries used, show all original rules.

115

4. Check minimum number of events

None

115

5. Include endpoints

None

115

6. Filter based on genotype QC (FinnGen only)

113

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF13

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 113 54 59
Unadjusted period prevalence (%) 0.02 0.02 0.03
Median age at first event (years) 71.68 73.10 70.38

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
115
Matched controls
1150
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Q39.6
ICD-10 Finland
Diverticulum of oesophagus
+∞
166.0
115
*
K22.5
ICD-10 Finland
Diverticulum of oesophagus, acquired
209.5
41.9
41
*
R13
ICD-10 Finland
Dysphagia
10.3
29.8
42
61
JCA60
NOMESCO Finland
Transcervical excision of diverticulum of oesophagus
211.2
18.1
18
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
5.1
17.1
69
260
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
6.6
14.0
26
49
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
42.6
12.5
15
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
5.0
11.2
28
69
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
3.7
10.1
44
164
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
5.4
10.0
22
48
WX402
NOMESCO Finland
General anaesthesia
3.8
9.4
36
122
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
22.1
8.7
12
6
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
17.2
7.4
11
7
A02BC05
ATC
esomeprazole; systemic
2.8
7.1
62
335

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
128
4.77
13.90
1.7
1.3
—
—
—
0
0
21
57
4.28
7.30
5.5
17.1
—
—
—
0
0
75
501
2.43
4.86
20.5
15.5
1.38
1.35
inr
0.09
16
144
68
440
2.33
4.68
4.0
4.5
35.74
34.47
g/l
1.04
63
405
18
64
3.15
4.18
3.6
6.3
26.54
25.34
mmol/l
0.85
18
64
51
304
2.22
4.14
3.2
2.7
54.11
70.52
u/l
0.53
46
277
64
418
2.20
4.13
2.5
2.0
95.30
93.27
pmol/l
0.12
24
210
14
44
3.48
3.92
1.0
1.3
—
—
—
0
0
50
302
2.16
3.87
3.3
2.5
—
—
—
0
0
71
492
2.16
3.84
4.9
8.0
1.22
1.21
mmol/l
0.48
60
413
73
517
2.13
3.66
6.5
8.8
4.42
4.49
e9/l
0.08
59
445
56
360
2.08
3.63
4.1
3.8
78.04
72.50
e6/l
0.05
38
266
91
709
2.36
3.51
8.2
7.5
79.54
82.27
u/l
0.20
85
661
40
232
2.11
3.36
1.7
1.7
1.30
1.27
mmol/l
0.08
33
182
37
209
2.14
3.32
1.3
1.3
—
—
—
0
0
60
408
1.98
3.23
5.7
5.7
—
—
—
0
0
50
320
2.00
3.19
3.2
3.3
17.15
257.93
e6/l
0.64
36
248
75
553
2.02
3.18
5.4
6.2
6.35
6.95
mmol/l
2.99
68
527
11
33
3.57
2.90
4.6
4.0
—
—
—
0
0
80
615
1.99
2.87
4.6
4.6
—
—
—
0
0
45
287
1.93
2.84
2.9
3.1
0.40
0.49
e6/l
0.16
31
217
41
255
1.94
2.77
2.7
2.0
2.88
3.15
mg/l
0.27
33
218
101
854
2.50
2.73
24.4
18.2
26.11
26.20
mg/l
0.01
85
690
40
250
1.92
2.65
1.8
1.6
20.40
20.64
nmol/l
0.03
33
208
29
162
2.06
2.63
2.0
1.7
29.69
29.48
s
0.08
29
157
28
157
2.04
2.51
2.7
3.0
1.81
3.03
e6/l
0.36
14
86
104
900
2.63
2.51
12.6
11.3
23.50
24.03
u/l
0.15
96
862
61
444
1.80
2.45
5.4
5.7
0.19
0.19
e9/l
0.02
50
378
52
363
1.79
2.39
2.6
2.2
—
—
—
0
0
42
276
1.82
2.34
3.0
3.0
—
—
—
0
0
13
54
2.59
2.29
2.3
2.4
—
—
—
0
0
61
452
1.74
2.24
4.7
7.3
1.22
1.21
mmol/l
0.60
55
408
18
89
2.21
2.20
4.9
9.4
—
—
—
0
0
34
214
1.84
2.16
3.3
3.3
499.00
531.93
mosm/kgh2o
0.36
24
181
103
902
2.36
2.15
28.0
22.1
139.14
139.52
mmol/l
0.66
98
878
103
905
2.32
2.08
28.4
22.0
3.97
4.00
mmol/l
0.55
98
882
104
920
2.36
2.02
33.9
26.1
240.64
238.66
e9/l
0.11
98
899
104
921
2.35
2.00
33.9
26.0
91.61
91.71
fl
0.07
99
907
104
921
2.35
2.00
34.1
26.3
38.81
39.45
%
0.50
95
871
104
921
2.35
2.00
34.1
26.2
129.76
132.82
g/l
1.29
99
906
104
921
2.35
2.00
33.8
25.9
30.36
30.42
pg
0.11
99
907
104
921
2.35
2.00
33.8
26.1
4.33
4.40
e12/l
0.68
98
891
104
922
2.34
1.97
33.7
26.1
6.96
6.99
e9/l
0.05
99
894
21
116
1.99
1.95
1.1
1.3
—
—
—
0
0
81
665
1.74
1.93
5.2
4.4
13.61
14.79
mm/h
0.33
74
599
58
442
1.63
1.80
5.6
5.5
1.85
1.91
e9/l
0.14
48
381
57
433
1.63
1.79
5.6
5.4
0.66
0.61
e9/l
0.79
46
362
57
435
1.62
1.74
5.6
5.4
0.05
0.04
e9/l
0.69
46
362
46
333
1.64
1.74
2.4
3.4
2.35
2.35
mmol/l
0.01
40
296
94
817
1.82
1.70
6.1
6.9
39.31
41.85
mmol/mol
3.02
85
754
36
247
1.67
1.66
2.0
2.8
363.13
4881.36
umol/l
1.07
30
205
91
788
1.74
1.61
5.5
4.7
2.12
2.06
mu/l
0.13
81
689
6
21
2.96
1.52
3.3
3.4
—
—
—
0
0
56
439
1.54
1.45
3.7
4.3
0.00
0.00
estimate
—
8
92
22
138
1.73
1.39
1.4
1.5
2.92
3.02
g/l
0.05
14
73
98
879
1.78
1.37
21.8
16.9
—
—
—
0
0
76
643
1.54
1.34
4.3
3.8
14.87
15.12
pmol/l
0.36
67
562
53
416
1.51
1.34
10.5
10.9
0.00
0.00
e9/l
0.07
42
343
33
233
1.58
1.34
2.7
2.7
4.57
4.32
e6/l
0.08
26
208
30
207
1.61
1.34
2.3
4.1
—
—
—
0
0
34
242
1.57
1.33
4.9
6.6
—
—
—
0
0
14
78
1.91
1.28
1.2
1.4
—
—
—
0
0
10
49
2.14
1.26
1.2
1.2
—
—
—
0
0
20
127
1.70
1.21
1.3
1.3
65.81
47.02
iu/ml
—
7
48
95
856
1.63
1.16
5.7
5.6
2.46
2.54
mmol/l
0.44
82
762
11
58
1.99
1.16
2.0
2.2
10.76
9.62
g/l
0.53
11
47
5
20
2.57
1.16
1.0
1.1
—
—
—
0
0
18
113
1.70
1.14
1.6
1.6
—
—
—
0
0
7
33
2.19
1.07
1.4
1.8
—
—
—
0
0
11
60
1.92
1.07
3.1
3.6
0.06
0.12
e6/l
0.56
11
60
54
441
1.42
1.05
5.8
5.7
0.00
0.00
estimate
—
7
82
54
444
1.41
1.00
3.8
4.3
0.00
0.00
estimate
—
5
80
9
50
1.87
0.99
1.3
1.6
0.89
1.18
g/l
—
9
42
11
62
1.86
0.98
1.5
1.4
—
—
—
0
0
73
641
1.38
0.87
5.5
4.3
—
—
—
0
0
38
300
1.40
0.87
5.8
4.6
—
—
—
0
0
8
45
1.83
0.86
1.3
1.3
—
—
—
0
0
27
201
1.45
0.85
2.7
3.0
0.69
0.73
ug/l
0.16
19
148
8
46
1.79
0.84
3.5
5.9
—
—
—
0
0
39
312
1.38
0.82
4.4
4.5
—
—
—
0
0
92
844
1.45
0.82
5.4
5.2
6.09
6.17
mmol/l
0.33
79
754
10
59
1.76
0.78
3.0
3.3
0.20
0.46
%
—
5
23
6
34
1.81
0.77
1.3
7.0
—
—
—
0
0
5
25
2.04
0.73
1.2
1.1
—
—
—
0
0
40
327
1.34
0.73
2.9
3.6
—
—
—
0
0
5
26
1.96
0.71
2.4
1.6
—
—
—
0
0
5
26
1.96
0.71
1.4
1.3
—
—
—
0
0
10
61
1.70
0.71
3.5
3.7
0.00
0.39
%
—
5
23
18
128
1.48
0.71
1.2
1.3
231.86
10.77
u/ml
—
7
43
90
831
1.38
0.69
5.0
4.8
1.37
1.45
mmol/l
1.09
79
733
90
835
1.36
0.63
5.0
4.9
4.28
4.42
mmol/l
0.74
79
748
20
261
0.72
0.63
3.7
4.4
0.00
0.00
estimate
—
6
82
29
231
1.34
0.62
1.7
1.7
785.02
1238.92
nmol/l
2.71
21
180
43
365
1.28
0.59
5.9
5.5
2.75
2.19
ug/l
0.35
38
317
15
107
1.46
0.59
1.1
1.3
—
—
—
0
0
13
91
1.48
0.56
3.2
3.8
—
—
—
0
0
13
92
1.47
0.53
1.2
1.6
—
—
—
0
0
6
40
1.53
0.52
1.2
1.3
—
—
—
0
0
86
805
1.27
0.48
4.2
4.4
1.24
1.26
mmol/l
0.16
75
705
5
33
1.54
0.42
4.4
3.7
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
5.42
—
0
17
0
17
0.00
0.41
0.0
3.1
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
65.18
—
0
17
24
200
1.25
0.38
1.8
1.7
1.08
1.55
mg/l
0.67
18
166
28
239
1.23
0.36
4.4
4.1
—
—
—
0
0
10
73
1.41
0.36
1.1
1.4
—
—
—
0
0
6
46
1.32
0.33
1.8
3.2
—
—
—
0
0
7
52
1.37
0.32
1.6
3.0
0.46
0.72
%
—
7
52
7
54
1.32
0.31
1.6
3.0
0.91
1.23
%
—
7
54
9
73
1.25
0.26
1.1
2.0
—
—
—
0
0
11
87
1.29
0.25
1.7
1.8
405.36
393.00
nmol/l
0.10
11
80
10
79
1.29
0.23
1.1
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
465.60
—
0
5
0
12
0.00
0.21
0.0
7.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
425.50
—
0
6
11
90
1.25
0.20
1.6
2.6
59.58
68.97
e9/l
—
6
68
10
81
1.26
0.19
5.6
9.5
—
—
—
0
0
8
69
1.17
0.17
1.9
3.2
—
7.43
—
0
7
9
78
1.17
0.16
2.6
3.6
95.33
75.25
ng/l
—
9
66
44
414
1.10
0.15
5.7
4.5
1473.61
51.82
ng/l
0.48
31
338
12
136
0.87
0.11
1.9
2.2
—
—
—
0
0
5
47
1.07
0.09
2.0
3.7
24.80
24.50
mmol/l
—
5
47
6
73
0.81
0.08
1.0
1.5
—
—
—
0
0
13
118
1.11
0.07
1.5
1.8
—
—
—
0
0
28
289
0.96
0.03
2.5
3.3
2212.04
56.88
mg/l
0.47
19
200
24
232
1.04
0.02
1.7
1.9
388.17
447.14
pmol/l
0.54
18
188
30
307
0.97
0.01
2.9
3.9
2.52
8.42
mg/mmol
2.45
20
198
26
254
1.03
0.00
3.1
3.6
—
—
—
0
0
20
195
1.03
0.00
5.0
4.9
1.02
1.02
kg/l
—
6
25
29
286
1.02
0.00
2.5
3.2
7.00
7.24
mmol/l
0.12
22
232
0
5
0.00
0.00
0.0
1.0
—
210.62
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
10.34
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
55.40
—
0
5
0
9
0.00
0.00
0.0
3.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.2
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.3
—
3.52
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
0.81
—
0
6
5
53
0.94
-0.00
1.0
1.3
—
—
—
0
0
8
87
0.91
-0.00
3.4
3.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.2
—
70.33
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
11.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
7.99
—
0
7
9
91
0.99
-0.00
1.3
1.5
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_ESOPHAGEAL_DIVERTICULUM_WIDE – Esophageal diverticulum (pouch)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).