Hereditary lymphedema

Q17_HEREDITARY_LYMPHEDEMA

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q82.0 Cause of death: ICD-10 — Q82.0 2 out of 7 registries used, show all original rules.	57
4. Check minimum number of events None	57
5. Include endpoints None	57
6. Filter based on genotype QC (FinnGen only)	55

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

NAME	Q17_HEREDITARY_LYMPHEDEMA
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q820
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q820
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Hereditary lymphedema based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	55	40	15
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	46.57	45.23	50.13

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
57: Matched controls
570

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q82.0

ICD-10 Finland

Hereditary lymphoedema

+∞

81.7

I89.0

ICD-10 Finland

Lymphoedema, not elsewhere classified

300.1

21.0

Z31.5

ICD-10 Finland

Genetic counselling

21.2

13.6

C03CA01

ATC

furosemide; systemic

5.7

9.7

PG1DE

NOMESCO Finland

Other extensive ultrasound examination of artery

16.4

8.9

C03EB01

ATC

furosemide and potassium-sparing agents; systemic

19.0

7.6

QD9S1

NOMESCO Finland

Photography of skin or subcutaneous tissue in lower extremities, unspecified

+∞

7.4

A46

ICD-10 Finland

Erysipelas

5.3

7.4

R4120

NOMESCO Finland

Occupational therapy

9.9

7.1

R60.0

ICD-10 Finland

Localized oedema

7.5

6.8

Q82.2

ICD-10 Finland

Mastocytosis

+∞

6.4

QDJ00

NOMESCO Finland

Liposuction in lower extremity

+∞

6.4

PJW20

NOMESCO Finland

Lymphovenous shunt

+∞

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3000991) Gas panel - Venous blood

4.79

3.63

3.8

6.1

—

(3023368) Bacteria identified in Blood by Culture

2.78

3.15

10.8

4.7

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

8.97

2.80

1.4

1.3

—

(3018418) pH of Serum or Plasma

106

2.55

2.71

6.7

4.0

7.41

—

(3000494) Fungus identified in Specimen by Culture

2.93

2.70

1.4

—

(3022145) Colonoscopy Study observation

3.01

2.66

1.2

1.3

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

107

2.52

2.65

2.0

1.74

0.69

mg/l

0.67

(3052851) Hemolysis interference index of Serum or Plasma

5.02

2.33

5.3

3.4

—

(3012110) Lysozyme [Mass/volume] in Serum or Plasma

5.96

2.26

2.6

1.3

5.04

10.34

mg/l

—

(40768797) Stomach Pathology biopsy report

2.61

2.09

1.4

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.79

2.07

3.5

1.4

—

(3002032) Base excess in Venous blood by calculation

3.04

2.04

4.7

3.5

0.31

1.72

mmol/l

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.66

1.91

2.2

3.0

206.64

250.55

u/l

1.43

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.47

1.89

3.2

2.68

3.64

e6/l

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

4.45

1.86

2.0

1.2

—

(3022948) Iron [Moles/volume] in Serum or Plasma

2.42

1.82

1.3

2.5

11.74

13.85

umol/l

0.52

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

3.81

1.65

3.0

1.2

1.23

1.17

g/l

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

3.81

1.65

3.0

1.2

0.27

0.24

g/l

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.35

1.63

1.6

2.5

2.49

2.38

g/l

0.22

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

121

2.01

1.58

1.5

1.6

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.81

1.57

4.6

4.4

1.13

1.30

mmol/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

149

1.91

1.49

5.0

2.8

—

(3014007) Fractional oxyhemoglobin in Arterial blood

3.32

1.47

3.2

7.3

95.68

95.09

—

(36304419) Bacteria [Presence] in Urine

116

1.96

1.45

5.3

2.6

—

(3030467) Casts [#/volume] in Urine by Automated count

117

1.94

1.41

5.6

2.9

0.30

0.37

e6/l

0.15

(3000330) Specific gravity of Urine by Test strip

2.79

1.40

2.3

3.7

—

(3018095) Leukocytes [#/volume] in Urine

152

1.86

1.38

5.4

3.5

61.99

44.69

e6/l

0.13

100

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

182

1.79

1.29

10.1

6.3

1.20

1.21

mmol/l

0.09

149

(40760892) CBC W Ordered Manual Differential panel - Blood

210

1.78

1.28

9.5

5.6

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.78

1.24

3.8

2.7

24.46

24.34

mmol/l

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

450

2.26

1.23

20.8

11.3

88.50

85.01

ml/min/173m2

0.47

360

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.04

1.20

3.2

3.1

0.40

0.64

e6/l

—

(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method

2.64

1.17

2.2

1.6

3.08

2.44

mg/l

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.64

1.17

4.8

7.5

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.95

1.14

2.6

3.2

16.40

64.54

ng/l

—

(3042936) Bacteria identified in Isolate by Culture

2.03

1.12

2.8

1.6

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.39

1.05

1.2

1.3

—

(1002224) Polysomnography panel

2.39

1.05

1.0

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

2.14

1.04

1.7

1.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.91

1.00

3.2

5.8

1.06

1.01

mmol/l

—

(3002385) Erythrocyte distribution width [Ratio]

423

1.85

0.96

30.5

14.4

14.26

14.53

0.17

413

(3002582) Erythrocytes [#/volume] in Urine

131

1.68

0.95

5.7

2.9

25.12

15.84

e6/l

0.47

(3004716) Salmonella sp identified in Stool by Organism specific culture

2.27

0.95

1.0

1.3

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.00

0.92

4.9

5.0

108.13

103.74

mmol/l

—

(3044640) Blood type and Crossmatch panel - Blood

141

1.64

0.91

3.0

2.2

—

(3021589) Normoblasts [#/volume] in Blood

208

1.57

0.85

19.3

8.8

0.00

e9/l

0.50

168

(3011397) Hemoglobin [Presence] in Urine by Test strip

103

1.62

0.74

2.8

3.3

—

(3022217) INR in Platelet poor plasma by Coagulation assay

199

1.46

0.64

22.7

13.7

1.32

1.13

inr

—

(3012095) Magnesium [Moles/volume] in Serum or Plasma

1.63

0.61

5.4

2.9

0.86

0.83

mmol/l

0.16

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

0.00

0.61

0.0

2.3

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.61

0.0

2.1

—

(40768793) Breast Pathology biopsy report

0.00

0.61

0.0

1.3

—

(3000570) Elastase.pancreatic [Mass/mass] in Stool

0.00

0.61

0.0

1.3

—

232.83

—

(3031040) Bacteria [#/volume] in Urine by Automated count

299

1.44

0.60

7.6

3.8

—

38.33

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

105

0.62

0.55

3.3

4.6

3.21

1.46

ug/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

166

1.42

0.54

2.2

1.9

94.55

97.10

pmol/l

0.08

(3026008) Bacteria identified in Urine by Culture

130

1.44

0.52

6.3

2.4

—

(3044889) 12 lead EKG panel

327

1.37

0.47

4.5

3.2

—

(3035350) Ketones [Presence] in Urine by Test strip

238

1.35

0.45

4.0

3.4

0.00

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

238

1.35

0.45

5.4

4.6

0.00

estimate

—

(21494755) Public health laboratory ask at order entry panel

1.53

0.45

1.4

1.3

—

(3002256) Pathology report gross observation

1.47

0.44

2.3

1.2

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.67

0.44

1.2

2.1

—

(4200892) Spirometry reversibility

1.62

0.43

1.2

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.62

0.43

4.6

3.3

4.08

4.52

pmol/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.42

0.42

3.3

2.1

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.42

0.0

1.4

—

(3009261) Glucose [Presence] in Urine by Test strip

241

1.32

0.41

4.0

3.4

0.00

estimate

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.40

0.0

1.4

—

(3013512) EKG study

133

0.70

0.39

7.3

3.6

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.34

0.39

1.4

1.5

—

(40758558) Short blood count panel - Blood

119

1.35

0.36

15.2

6.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.34

0.34

2.3

1.7

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.42

0.33

3.6

3.1

—

(1761868) Lipid panel - Serum or Plasma

188

1.28

0.32

3.0

2.8

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

190

1.26

0.29

4.3

3.3

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.32

0.28

2.3

1.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.32

0.27

1.8

1.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

115

1.29

0.27

1.6

1.2

2.16

0.72

u/ml

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.35

0.24

1.8

1.6

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.35

0.24

1.8

2.2

15.28

3.51

ug/l

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.24

0.22

1.8

1.5

—

(40761536) Microorganisms panel - Urine sediment

1.21

0.22

6.8

3.6

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.1

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

3.3

—

77.95

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.21

0.0

2.9

—

3.87

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

1.8

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.31

0.21

2.3

1.7

—

(36660697) Celiac disease serology panel - Serum

1.31

0.21

1.0

1.1

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

5.2

—

30.47

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.22

0.20

1.8

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.20

0.0

1.2

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.4

—

62.79

—

(3003694) ABO and Rh group [Type] in Blood

130

1.21

0.18

1.1

1.6

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.17

0.17

1.4

1.7

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

209

1.17

0.16

3.1

2.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

351

1.15

0.14

3.4

3.7

—

(40768804) Tissue Pathology biopsy report

197

0.87

0.12

3.1

1.9

—

(3041096) Erythrocytes [Presence] in Urine by Automated

144

1.15

0.12

4.2

3.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

115

1.17

0.12

1.8

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.07

0.10

6.4

7.7

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.82

0.09

1.4

1.8

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

487

1.22

0.07

27.5

13.3

3.93

3.95

mmol/l

0.10

471

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.08

0.01

1.3

1.4

—

(3021960) Folate [Moles/volume] in Serum or Plasma

104

1.07

0.01

1.8

1.5

18.10

20.31

nmol/l

0.29

(3037467) Urinalysis macro (dipstick) panel - Urine

329

1.01

0.00

6.5

3.9

—

(3012516) Albumin [Mass/volume] in Urine

114

0.96

0.00

3.4

2.9

88.62

86.81

mg/l

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.0

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

0.0

1.3

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

5.4

—

28.09

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.88

0.00

1.0

1.6

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.1

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.7

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

2.2

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

0.0

1.3

—

13.00

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.01

-0.00

2.1

1.9

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(3007368) IgG [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

42.36

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

303.80

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

11.59

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.02

-0.00

1.1

1.6

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.8

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

2.4

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

2.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.4

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(40761511) CBC panel - Blood by Automated count

513

1.16

-0.00

19.1

12.2

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

487

1.04

-0.00

27.8

13.1

139.18

139.82

mmol/l

1.61

472

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.2

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.2

—

(3023419) Bacteria identified in Sputum by Culture

0.00

-0.00

0.0

2.4

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3029937) Albumin [Presence] in Urine by Test strip

130

1.00

-0.00

5.3

3.6

0.20

0.00

estimate

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

1.68

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

67.60

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.0

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: Q17_HEREDITARY_LYMPHEDEMA – Hereditary lymphedema

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Hereditary lymphedema

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Hereditary lymphedema (Q17_HEREDITARY_LYMPHEDEMA)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints