Other and unspecified postprocedural disorders of eye and adnexa

H7_POSTOPEYENAS

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — H59.8, H59.9 Cause of death: ICD-10 — H59.8, H59.9 2 out of 7 registries used, show all original rules.	77
4. Check minimum number of events None	77
5. Include endpoints None	77
6. Filter based on genotype QC (FinnGen only)	71

Control definitions (FinnGen only)

Control exclude: H7_EYEPOSTOP

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2

NAME	H7_POSTOPEYENAS
CONTROL_EXCLUDE	H7_EYEPOSTOP
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H59[8-9]
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H59[8-9]
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Other and unspecified postprocedural disorders of eye and adnexa based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	541	282	257
Only index persons	456	238	218
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	71.21	72.30	70.00
Only index persons	69.97	70.56	69.33

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	71	41	30
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	72.04	72.68	71.17

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
77: Matched controls
770

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

H59.8

ICD-10 Finland

Other postprocedural disorders of eye and adnexa

+∞

44.0

H59.9

ICD-10 Finland

Postprocedural disorder of eye and adnexa, unspecified

777.2

43.8

Z96.1

ICD-10 Finland

Presence of intraocular lens

9.3

22.1

WX100

NOMESCO Finland

Conjunctival surface anesthesia

8.6

19.8

S01ED51

ATC

timolol, combinations; ophthalmic

8.7

15.6

WX140

NOMESCO Finland

Parabulbar anesthesy

17.0

15.5

CKD94

NOMESCO Finland

Combined vitrectomy and procedure on lens through pars plana

35.7

13.6

CKD60

NOMESCO Finland

Anterior vitrectomy

45.8

12.7

CHB10

NOMESCO Finland

Puncture of anterior chamber of eye with irrigation

36.6

12.2

CJE99

NOMESCO Finland

Other extracapsular cataract operation using phakoemulsification technique

+∞

11.8

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic

4.9

10.4

229

CJE20

NOMESCO Finland

Phakoemulsification with implantation of artificial lens in posterior chamber

5.0

9.9

258

CJW99

NOMESCO Finland

Other operation on lens

+∞

9.6

CK2S4

NOMESCO Finland

Plain photography of ocular fundus

8.9

9.3

H33.0

ICD-10 Finland

Retinal detachment with retinal break

13.0

8.8

H25.8

ICD-10 Finland

Other senile cataract

4.5

7.7

H27.0

ICD-10 Finland

Aphakia

88.2

7.6

CJF10

NOMESCO Finland

Secondary implantation of artificial lens in posterior chamber

+∞

7.4

CKD40

NOMESCO Finland

Endophotocoagulation of retina

22.6

7.3

CKD20

NOMESCO Finland

Removal of vitreous body substitute

44.1

6.9

CKD65

NOMESCO Finland

Pars plana or pars plicata vitrectomy

11.6

6.8

T85.2

ICD-10 Finland

Mechanical complication of intraocular lens

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3019225) pH of Specimen

5.13

8.92

3.4

5.4

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

4.22

7.58

4.4

5.0

30.69

33.07

0.46

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

6.03

5.04

1.3

2.0

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

4.70

3.90

1.2

2.0

—

(3013512) EKG study

211

2.45

3.61

4.9

4.8

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

295

2.39

3.39

4.8

6.1

1.23

1.21

mmol/l

1.71

267

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

337

2.38

3.23

4.8

6.6

1.23

1.21

mmol/l

1.40

275

(3022313) Gas panel - Capillary blood

3.63

2.48

2.7

3.5

—

(3013115) Eosinophils [#/volume] in Blood

315

2.03

2.35

4.9

6.0

0.16

0.18

e9/l

0.67

281

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

377

2.04

2.25

3.1

3.0

66.07

52.35

u/l

0.28

346

(3009343) pH of Capillary blood

2.87

2.09

2.5

3.4

—

7.45

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

286

1.93

2.09

2.0

90.69

96.54

pmol/l

0.25

132

(3001604) Monocytes [#/volume] in Blood

305

1.93

2.08

4.9

5.8

0.64

0.60

e9/l

0.59

269

(3006315) Basophils [#/volume] in Blood

306

1.92

2.05

5.0

5.9

0.04

e9/l

0.04

269

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

117

2.09

2.00

1.2

1.3

58.40

38.83

iu/ml

—

(40760892) CBC W Ordered Manual Differential panel - Blood

290

1.89

1.97

4.8

6.5

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

263

1.88

1.94

2.2

75.53

79.07

nmol/l

0.25

225

(40758558) Short blood count panel - Blood

173

0.40

1.90

5.4

7.0

—

(3019198) Lymphocytes [#/volume] in Blood

314

1.84

1.82

5.0

5.8

1.86

1.79

e9/l

0.20

284

(3013707) Erythrocyte sedimentation rate by Westergren method

478

2.00

1.79

5.7

4.5

12.64

13.18

mm/h

0.13

426

(3013826) Glucose [Moles/volume] in Serum or Plasma

397

1.84

1.71

3.5

4.8

6.78

6.71

mmol/l

0.07

367

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.58

1.69

1.2

2.0

—

(3044640) Blood type and Crossmatch panel - Blood

209

1.81

1.67

1.9

2.5

—

(36660697) Celiac disease serology panel - Serum

2.52

1.66

1.0

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

150

1.87

1.64

2.1

2.6

—

(40761511) CBC panel - Blood by Automated count

635

2.51

1.60

15.5

16.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

2.03

1.56

4.3

7.6

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

116

1.85

1.38

1.5

2.1

—

(1761868) Lipid panel - Serum or Plasma

207

0.50

1.37

4.8

3.6

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

305

1.65

1.32

2.3

2.7

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

580

1.97

1.24

5.0

4.8

2.10

1.98

mu/l

0.35

506

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

620

2.09

1.19

14.9

16.9

20.77

23.38

mg/l

0.34

504

(3013650) Neutrophils [#/volume] in Blood by Automated count

362

1.58

1.14

5.7

10.2

4.58

4.45

e9/l

0.12

324

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

586

1.88

1.11

13.2

16.4

73.22

75.97

ml/min/173m2

0.46

476

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.30

1.11

1.1

1.3

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.10

1.03

3.6

7.9

—

(40761535) Cells panel - Urine sediment

1.98

1.02

5.0

3.2

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.99

0.0

1.5

—

(3022621) pH of Urine by Test strip

1.96

0.91

3.3

2.6

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

597

1.74

0.89

5.4

5.2

5.94

6.03

mmol/l

0.27

527

(3019309) Folate [Moles/volume] in Red Blood Cells

158

1.55

0.87

1.5

1.8

899.23

1293.76

nmol/l

1.81

110

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.78

0.83

1.1

1.6

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

578

1.64

0.82

4.1

4.3

1.22

1.24

mmol/l

0.12

508

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.80

0.0

2.7

—

4.00

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

629

1.69

0.79

4.9

5.4

2.64

2.61

mmol/l

0.09

556

(3020891) Body temperature

0.00

0.79

0.0

4.1

—

(3021589) Normoblasts [#/volume] in Blood

287

0.67

0.78

5.3

11.7

0.00

e9/l

0.50

243

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.16

0.76

1.0

—

(36304419) Bacteria [Presence] in Urine

185

0.64

0.69

3.4

3.1

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.65

0.67

3.1

2.6

9.27

9.11

g/l

—

(3004588) Protein electrophoresis panel - Serum or Plasma

1.65

0.67

1.6

2.2

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

178

1.42

0.63

1.8

2.1

2.78

2.97

mg/l

0.19

153

(3020682) Albumin/Creatinine [Ratio] in Urine

216

1.39

0.61

4.7

3.6

19.39

9.82

mg/mmol

0.25

130

(3019060) Gas panel - Arterial blood

1.57

0.60

1.5

2.8

—

(3001019) Free T4 and TSH panel - Serum or Plasma

0.00

0.60

0.0

1.7

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

0.00

0.60

0.0

1.4

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.60

0.0

2.3

—

0.31

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.59

0.0

1.4

—

(3023368) Bacteria identified in Blood by Culture

180

1.40

0.59

2.2

5.0

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

306

0.73

0.58

4.2

4.1

35.41

34.78

g/l

0.19

283

(3012516) Albumin [Mass/volume] in Urine

199

1.38

0.58

4.8

2.9

66.60

68.18

mg/l

0.01

120

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

295

1.34

0.57

4.3

4.1

48.12

50.23

ng/l

0.04

218

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

604

1.49

0.55

4.6

4.8

4.58

4.53

mmol/l

0.13

542

(40768804) Tissue Pathology biopsy report

262

0.73

0.55

2.4

2.1

—

(3042936) Bacteria identified in Isolate by Culture

107

0.62

0.53

1.3

2.2

—

(3018095) Leukocytes [#/volume] in Urine

238

0.73

0.50

3.5

3.9

12.46

66.98

e6/l

2.62

174

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

480

1.33

0.50

3.5

3.8

15.48

14.99

pmol/l

0.67

416

(4200892) Spirometry reversibility

1.44

0.46

2.0

1.4

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

600

1.39

0.44

4.8

1.56

1.49

mmol/l

0.55

532

(3037467) Urinalysis macro (dipstick) panel - Urine

445

1.28

0.42

5.9

4.9

—

(1616796) Gas panel - Central venous blood

0.00

0.41

0.0

3.9

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.41

0.0

1.3

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.41

0.0

1.0

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

0.41

0.0

4.4

—

5.03

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.6

—

(3012501) Base excess in Blood by calculation

0.00

0.41

0.0

4.4

—

2.10

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

0.41

0.0

1.6

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

0.41

0.0

4.4

—

7.94

—

(3026008) Bacteria identified in Urine by Culture

221

0.76

0.41

3.3

3.7

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

0.40

0.0

3.2

—

15.90

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.39

0.0

2.4

—

125.15

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.39

0.0

2.7

—

54.84

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.42

0.39

3.0

2.7

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

650

1.39

0.39

17.7

19.5

80.65

81.26

umol/l

0.06

650

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

261

0.78

0.38

4.4

4.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.61

0.37

1.2

1.4

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

248

0.79

0.35

3.4

3.2

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

243

1.24

0.33

2.5

3.3

1359.43

1652.15

ng/l

0.19

194

(3009508) Creatinine [Moles/volume] in Urine

205

1.25

0.33

4.7

2.8

6.86

7.43

mmol/l

0.31

165

(3044889) 12 lead EKG panel

438

0.82

0.32

3.5

4.3

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

235

1.23

0.31

2.4

3.5

2.40

2.35

mmol/l

1.05

200

(3041096) Erythrocytes [Presence] in Urine by Automated

193

0.78

0.31

3.3

4.1

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.26

0.28

1.5

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.65

0.27

1.4

1.5

—

(3021960) Folate [Moles/volume] in Serum or Plasma

182

1.21

0.25

1.9

1.6

18.36

22.33

nmol/l

0.48

147

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

593

1.23

0.24

7.1

6.5

39.66

40.94

mmol/mol

0.66

536

(46235355) HIV 1 and 2 tests - Meaningful Use set

0.74

0.24

1.4

1.8

—

(3007164) IgA [Mass/volume] in Serum or Plasma

126

1.24

0.23

1.2

1.5

2.45

3.00

g/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.23

0.22

2.8

—

(3000330) Specific gravity of Urine by Test strip

1.23

0.22

5.0

4.8

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.5

—

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

2.7

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3045142) Bone marrow Pathology biopsy report

0.00

0.21

0.0

1.3

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.21

0.0

1.5

—

4.97

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

2.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.2

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.21

0.0

1.5

—

60.70

—

(40768795) Lymph node Pathology biopsy report

0.00

0.21

0.0

1.1

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.21

0.0

2.6

—

88.97

—

(21494434) Karyotype in Bone marrow

0.00

0.21

0.0

1.0

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.20

0.0

1.6

—

(4035726) Immunohistochemistry procedure

0.71

0.17

1.4

1.3

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.17

0.16

1.6

2.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.14

0.16

1.4

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.20

0.13

1.2

1.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

320

1.11

0.13

2.7

2.8

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.12

0.10

1.6

1.4

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.04

0.09

1.4

1.7

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.06

0.09

1.7

1.4

1.87

1.42

—

(3002256) Pathology report gross observation

1.11

0.08

1.0

1.2

—

(3000494) Fungus identified in Specimen by Culture

1.04

0.07

1.0

1.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

1.05

0.07

4.9

5.0

1.11

1.04

mmol/l

—

(3003694) ABO and Rh group [Type] in Blood

161

0.92

0.05

1.4

—

(3022217) INR in Platelet poor plasma by Coagulation assay

332

1.04

0.02

24.0

17.7

1.82

1.33

inr

—

101

(3011397) Hemoglobin [Presence] in Urine by Test strip

137

0.94

0.02

5.0

3.6

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

176

0.96

0.00

4.5

22.03

22.76

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

3.2

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

3.2

—

(21494815) CD4 cells/100 lymphocytes in Specimen

0.00

0.0

1.5

—

32.80

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

0.0

2.2

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

2.8

—

30.17

—

(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.7

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3017704) Immunofixation for Urine

0.00

0.0

1.0

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

255.33

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.3

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.7

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

2.2

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.1

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.4

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.8

—

(3023410) Appearance of Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.1

—

2.71

—

(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(3022145) Colonoscopy Study observation

1.02

-0.00

1.1

1.3

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.6

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.1

—

(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.01

-0.00

1.5

2.0

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

0.97

-0.00

2.8

2.0

0.21

0.22

g/l

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

2.8

—

60.00

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

1.6

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

1.71

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.3

—

(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells

0.00

-0.00

0.0

2.3

—

(3038177) Helicobacter pylori Ab [Presence] in Serum

0.00

-0.00

0.0

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

3.4

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.4

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

4.6

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

5.86

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

2.6

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.4

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

0.85

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

3.4

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(40768797) Stomach Pathology biopsy report

0.94

-0.00

1.2

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.1

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.2

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint H7_POSTOPEYENAS and mortality.

Females

Parameter	HR [95% CI]	p-value
H7_POSTOPEYENAS	1.186 [0.87, 1.61]	0.277
Birth year	0.998 [0.99, 1.01]	0.592

During the follow-up period (1.1.1998 — 31.12.2019), 77 out of 221 females with H7_POSTOPEYENAS died.

Males

Parameter	HR [95% CI]	p-value
H7_POSTOPEYENAS	1.221 [0.89, 1.68]	0.222
Birth year	0.987 [0.98, 1.0]	0.009

During the follow-up period (1.1.1998 — 31.12.2019), 87 out of 207 males with H7_POSTOPEYENAS died.

Mortality risk

Mortality risk for people of age

years, who have H7_POSTOPEYENAS.

N-year risk	Females	Males
1	0.158%	0.267%
5	0.729%	1.541%
10	1.938%	3.612%
15	3.787%	6.642%
20	6.666%	11.455%

Relationships between endpoints

↥

Index endpoint: H7_POSTOPEYENAS – Other and unspecified postprocedural disorders of eye and adnexa

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other and unspecified postprocedural disorders of eye and adnexa

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints