Postprocedural disorders of eye and adnexa, not elsewhere classified

H7_EYEPOSTOP

eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H59
  • Cause of death: ICD-10 H59

2 out of 7 registries used, show all original rules.

92

4. Check minimum number of events

None

92

5. Include endpoints

92

6. Filter based on genotype QC (FinnGen only)

92

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H55-H59
Name in latin
Morbositates oculi et organorum accessoriorum post interventiones non alibi classificatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 873 487 378
Only index persons 737 418 319
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.02 0.01
Median age at first event (years)
Whole population 72.77 74.62 70.31
Only index persons 71.58 73.40 69.20

-FinnGen-

Key figures

All Female Male
Number of individuals 92 52 40
Unadjusted period prevalence (%) 0.02 0.02 0.02
Median age at first event (years) 71.47 73.67 68.62

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
75
Matched controls
748
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H59.9
ICD-10 Finland
Postprocedural disorder of eye and adnexa, unspecified
+∞
32.7
29
*
H59.8
ICD-10 Finland
Other postprocedural disorders of eye and adnexa
+∞
26.6
24
*
H59.0
ICD-10 Finland
Keratopathy (bullous aphakic) following cataract surgery
+∞
21.9
20
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
13.4
21.1
43
68
CKD60
NOMESCO Finland
Anterior vitrectomy
184.5
15.0
15
*
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
+∞
14.0
13
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
6.3
12.5
54
216
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
70.3
11.0
12
*
WX140
NOMESCO Finland
Parabulbar anesthesy
14.4
10.8
18
16
WX100
NOMESCO Finland
Conjunctival surface anesthesia
6.4
9.2
26
57
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
4.7
9.2
48
207
H33.0
ICD-10 Finland
Retinal detachment with retinal break
17.5
8.0
12
8
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
12.8
7.6
13
12
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
+∞
7.4
7
*
CJE99
NOMESCO Finland
Other extracapsular cataract operation using phakoemulsification technique
+∞
7.4
7
*
S01ED51
ATC
timolol, combinations; ophthalmic
6.4
6.9
18
35
CKD20
NOMESCO Finland
Removal of vitreous body substitute
76.0
6.5
7
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
59
350
2.91
5.69
5.3
5.5
mmol/l
1.2
1.2
1.07
49
319
(3019225) pH of Specimen
20
67
3.54
5.21
3.3
4.4
—
—
—
0
0
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
62
400
2.69
4.73
6.2
6.0
mmol/l
1.2
1.2
1.32
52
324
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
22
94
2.76
3.77
4.1
5.3
%
29.6
32.8
0.62
12
50
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
10
30
3.62
3.00
1.4
2.1
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
85
726
3.24
2.85
16.7
16.8
mg/l
30.5
23.9
0.72
76
599
(42870588) Differential panel, method unspecified - Blood
40
251
2.05
2.79
3.6
5.2
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
13
49
2.93
2.76
1.0
1.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
11
38
3.15
2.68
7.5
7.4
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
86
747
3.32
2.64
16.3
16.4
—
—
—
0
0
(3002030) Lymphocytes/100 leukocytes in Blood
49
341
1.93
2.47
4.8
5.7
%
24.2
25.9
0.46
44
309
(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma
58
431
1.94
2.37
2.6
3.0
u/l
51.5
54.3
0.06
48
400
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
49
348
1.87
2.26
3.2
4.2
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
50
359
1.86
2.22
5.0
5.2
e9/l
0.6
0.6
0.57
43
308
(3006315) Basophils [#/volume] in Blood
50
361
1.84
2.16
5.0
5.3
e9/l
0.0
0.0
0.01
43
310
(3013115) Eosinophils [#/volume] in Blood
51
373
1.82
2.09
5.1
5.4
e9/l
0.2
0.2
0.47
43
330
(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma
25
146
1.98
2.05
3.6
3.6
ng/l
17.0
113.8
1.18
20
123
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
28
171
1.92
2.02
1.7
2.1
—
—
—
0
0
(3019198) Lymphocytes [#/volume] in Blood
50
367
1.79
2.00
5.1
5.3
e9/l
1.7
1.8
0.05
44
329
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
9
33
2.91
1.99
1.3
2.2
—
—
—
0
0
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
23
133
1.97
1.93
1.5
2.0
—
—
—
0
0
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
78
667
2.11
1.81
5.0
4.7
mu/l
2.0
2.0
0.05
69
583
(3044640) Blood type and Crossmatch panel - Blood
35
239
1.75
1.74
1.7
2.3
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
69
570
1.84
1.74
4.5
4.3
mm/h
11.6
13.6
0.79
64
506
(3013512) EKG study
36
249
1.73
1.71
5.0
4.5
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
55
428
1.71
1.69
7.3
9.2
e9/l
4.7
4.4
0.33
48
375
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
7
25
2.94
1.68
1.0
1.0
—
—
—
0
0
(3003396) Base excess in Arterial blood by calculation
17
94
1.99
1.60
6.0
6.0
mmol/l
-1.8
1.5
—
8
74
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
45
339
1.64
1.51
2.2
2.0
pmol/l
85.4
94.5
0.56
21
150
(3023368) Bacteria identified in Blood by Culture
32
222
1.68
1.47
3.7
4.6
—
—
—
0
0
(3020564) Creatinine [Moles/volume] in Serum or Plasma
84
761
2.19
1.42
20.5
19.6
umol/l
80.3
81.3
0.13
84
761
(3012516) Albumin [Mass/volume] in Urine
33
233
1.65
1.41
3.9
3.0
mg/l
56.8
70.5
0.12
18
142
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
65
549
1.63
1.28
3.6
3.8
pmol/l
15.4
15.1
0.48
56
476
(3009542) Hematocrit [Volume Fraction] of Blood
71
613
1.69
1.28
17.9
18.0
%
38.7
39.8
0.35
36
382
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
8
38
2.21
1.22
2.1
3.3
g/l
1.4
1.3
—
8
33
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
15
88
1.84
1.20
1.4
1.8
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
77
684
1.77
1.19
16.5
16.5
ml/min/173m2
72.6
74.7
0.35
59
563
(1761868) Lipid panel - Serum or Plasma
15
231
0.58
1.10
3.7
3.7
—
—
—
0
0
(3019060) Gas panel - Arterial blood
11
60
1.95
1.08
2.8
2.8
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
11
60
1.95
1.08
2.2
1.6
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
9
46
2.06
1.07
1.2
1.8
—
—
—
0
0
(3020682) Albumin/Creatinine [Ratio] in Urine
33
248
1.52
1.05
4.4
4.0
mg/mmol
19.4
10.9
0.22
16
149
(3009508) Creatinine [Moles/volume] in Urine
32
239
1.52
1.05
3.8
2.9
mmol/l
6.7
7.1
0.25
25
186
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
78
704
1.71
1.02
5.2
5.2
mmol/l
6.1
6.1
0.08
68
627
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
40
315
1.48
1.01
2.4
2.3
nmol/l
74.9
78.0
0.23
35
267
(3022621) pH of Urine by Test strip
10
54
1.96
1.01
4.1
2.6
—
—
—
0
0
(21494755) Public health laboratory ask at order entry panel
0
32
0.00
0.97
0.0
1.5
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
44
356
1.45
0.96
3.8
3.9
ng/l
42.2
47.9
0.13
28
265
(3019832) Treponema pallidum Ab [Presence] in Serum
8
42
1.99
0.91
1.3
1.8
—
—
—
0
0
(3022313) Gas panel - Capillary blood
6
29
2.14
0.91
2.8
4.1
—
—
—
0
0
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
14
89
1.68
0.87
1.4
1.9
—
—
—
0
0
(3037467) Urinalysis macro (dipstick) panel - Urine
60
523
1.42
0.82
5.7
5.0
—
—
—
0
0
(3012544) pH of Venous blood
12
76
1.67
0.76
2.4
3.6
—
—
—
0
0
(3013139) Helicobacter pylori Ag [Presence] in Stool
7
38
1.91
0.75
1.0
1.3
—
—
—
0
0
(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation
7
43
1.68
0.68
2.7
3.8
mmol/l
1.2
2.0
—
7
32
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
35
286
1.36
0.67
2.5
3.4
ng/l
1653.9
1803.7
0.10
28
234
(3009445) Proteinase 3 Ab [Units/volume] in Serum
5
28
1.83
0.67
1.8
1.0
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
17
229
0.68
0.67
4.3
4.4
estimate
0.0
0.0
—
8
81
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
7
44
1.64
0.67
9.6
8.6
mmol/l
20.8
24.9
—
7
38
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
25
314
0.72
0.66
3.8
4.4
—
—
—
0
0
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
73
670
1.43
0.66
4.0
4.3
mmol/l
1.3
1.2
0.32
62
595
(3045414) Leukocytes [Presence] in Urine
5
29
1.76
0.65
4.8
1.8
—
—
—
0
0
(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection
5
29
1.76
0.65
1.0
1.4
—
—
—
0
0
(3032080) INR in Blood by Coagulation assay
40
336
1.34
0.64
9.5
10.3
inr
1.5
1.3
—
9
114
(3005719) IgG [Mass/volume] in Serum or Plasma
8
49
1.69
0.64
3.6
2.5
g/l
8.7
9.7
—
8
39
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
78
728
1.47
0.60
4.9
5.4
mmol/l
2.6
2.6
0.02
66
644
(3001019) Free T4 and TSH panel - Serum or Plasma
0
23
0.00
0.59
0.0
1.7
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
18
134
1.43
0.59
1.3
1.3
iu/ml
51.5
35.6
—
6
41
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
75
697
1.41
0.57
4.5
4.8
mmol/l
4.6
4.5
0.14
65
626
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
6
97
0.59
0.55
5.5
3.9
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
13
92
1.48
0.54
1.3
1.5
—
—
—
0
0
(40761535) Cells panel - Urine sediment
10
67
1.55
0.52
3.0
3.5
—
—
—
0
0
(3019309) Folate [Moles/volume] in Red Blood Cells
23
185
1.32
0.48
1.7
1.7
nmol/l
824.3
1273.6
3.26
18
131
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
8
56
1.47
0.44
2.0
1.3
—
—
—
0
0
(3049717) Cytology report of Urine Cyto stain
5
32
1.59
0.43
3.0
2.6
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
5
33
1.54
0.42
1.0
1.0
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
5
33
1.54
0.42
1.4
1.4
—
—
—
0
0
(3010156) C reactive protein [Mass/volume] in Serum or Plasma by High sensitivity method
0
15
0.00
0.41
0.0
1.5
—
3.7
—
0
10
(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
15
0.00
0.41
0.0
1.3
—
—
—
0
0
(3022806) Fractional oxyhemoglobin in Capillary blood
0
15
0.00
0.41
0.0
2.3
—
87.8
—
0
15
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
19
231
0.78
0.38
4.3
4.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
13
99
1.36
0.38
4.5
7.5
—
—
—
0
0
(4035726)
5
76
0.64
0.37
1.2
1.3
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
26
221
1.25
0.36
1.9
1.5
nmol/l
19.2
22.8
0.60
19
179
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
73
693
1.26
0.33
4.6
4.9
mmol/l
1.5
1.5
0.15
63
616
(36304419) Bacteria [Presence] in Urine
26
224
1.22
0.32
3.7
3.1
—
—
—
0
0
(3000494) Fungus identified in Specimen by Culture
12
93
1.33
0.32
1.0
1.4
—
—
—
0
0
(3030467) Casts [#/volume] in Urine by Automated count
27
235
1.21
0.30
3.8
3.2
e6/l
1.0
0.5
0.36
22
178
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
5
72
0.68
0.27
1.6
1.5
—
—
—
0
0
(3044889) 12 lead EKG panel
56
524
1.18
0.27
3.6
4.4
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
40
365
1.17
0.26
2.5
2.7
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
17
143
1.23
0.25
1.2
1.4
g/l
2.9
2.9
—
10
72
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
33
297
1.17
0.25
4.0
3.4
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
6
80
0.73
0.25
5.5
4.1
—
—
—
0
0
(3015377) Calcium [Moles/volume] in Serum or Plasma
32
290
1.16
0.22
2.0
3.3
mmol/l
2.4
2.3
2.41
22
247
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
5
42
1.20
0.22
2.6
2.4
—
—
—
0
0
(3004775) Volume in Urine collected for unspecified duration
0
11
0.00
0.21
0.0
1.8
—
434.6
—
0
5
(3012568) Campylobacter sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
(3025468) Yersinia sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
(3024522) Salmonella sp identified in Specimen by Organism specific culture
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
(40768795) Lymph node Pathology biopsy report
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
(3027544) Mycobacterium sp identified in Sputum by Organism specific culture
0
10
0.00
0.21
0.0
4.4
—
—
—
0
0
(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
9
113
0.77
0.21
1.3
1.2
—
—
—
0
0
(3005988) Vibrio sp identified in Specimen by Organism specific culture
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma
0
12
0.00
0.21
0.0
1.9
—
312.6
—
0
12
(40758558) Short blood count panel - Blood
17
193
0.85
0.18
8.6
6.9
—
—
—
0
0
(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma
7
62
1.14
0.18
1.9
1.5
%
1.7
1.4
—
7
51
(4010399)
5
65
0.76
0.17
2.2
1.4
—
—
—
0
0
(3018095) Leukocytes [#/volume] in Urine
31
286
1.13
0.16
4.8
4.3
e6/l
20.3
65.8
2.16
25
213
(3003458) Phosphate [Moles/volume] in Serum or Plasma
12
102
1.20
0.16
3.4
4.8
mmol/l
1.1
1.0
0.13
12
92
(3021589) Normoblasts [#/volume] in Blood
32
344
0.89
0.15
9.6
11.5
e9/l
0.0
0.0
0.52
23
288
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
71
688
1.14
0.15
7.1
6.8
mmol/mol
40.8
41.4
0.18
62
625
(46235355) HIV 1 and 2 tests - Meaningful Use set
7
86
0.80
0.15
1.4
1.9
—
—
—
0
0
(40768804) Tissue Pathology biopsy report
28
299
0.91
0.11
2.2
2.2
—
—
—
0
0
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
5
48
1.04
0.09
9.2
6.1
mmol/l
22.2
25.0
—
5
48
(3030981) Hyaline casts [#/volume] in Urine by Automated count
5
48
1.04
0.09
3.6
4.3
e6/l
0.0
0.1
—
5
48
(3004588) Protein electrophoresis panel - Serum or Plasma
6
53
1.14
0.09
1.7
2.0
—
—
—
0
0
(3035350) Ketones [Presence] in Urine by Test strip
37
387
0.93
0.09
3.8
4.2
estimate
0.0
0.0
—
8
86
(3000991) Gas panel - Venous blood
6
58
1.04
0.08
13.0
8.4
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
7
63
1.12
0.08
1.4
1.4
—
—
—
0
0
(3003694) ABO and Rh group [Type] in Blood
17
183
0.91
0.07
1.5
1.4
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
28
266
1.08
0.07
3.8
3.9
—
—
—
0
0
(3002256) Pathology report gross observation
9
87
1.04
0.07
1.1
1.2
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
17
161
1.07
0.03
3.1
3.8
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
38
390
0.96
0.03
4.8
5.6
estimate
0.0
0.0
—
8
82
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
15
148
1.02
0.00
3.5
2.9
ug/l
0.4
0.8
—
8
95
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
10
97
1.03
0.00
1.2
1.5
—
—
—
0
0
(3024561) Albumin [Mass/volume] in Serum or Plasma
36
363
0.99
0.00
4.4
4.2
g/l
33.1
34.7
0.69
31
340
(40760892) CBC W Ordered Manual Differential panel - Blood
16
155
1.04
0.00
5.0
4.3
—
—
—
0
0
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
20
201
0.99
0.00
4.8
4.4
%
21.7
22.5
—
8
99
(3042936) Bacteria identified in Isolate by Culture
12
119
1.01
0.00
1.3
2.2
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
39
394
0.98
0.00
3.7
4.2
estimate
0.0
0.0
—
8
78
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
5
52
0.96
0.00
13.0
7.8
%
1.8
1.5
—
5
52
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3009340) Metanephrine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3004451) EKG impression Narrative
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3004616) Nuclear Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
5
49
1.02
0.00
1.2
1.2
—
—
—
0
0
(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay
0
5
0.00
0.00
0.0
1.2
—
107.0
—
0
5
(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(40759836) Histone Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035947) Staphylolysin Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(4281824)
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3022145) Colonoscopy Study observation
8
84
0.95
0.00
1.1
1.3
—
—
—
0
0
(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000012) Reticulocyte production index
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
(3013566) Clostridioides difficile [Presence] in Stool by Organism specific culture
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3029075) Extractable nuclear Ab panel - Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3012447) Hantavirus puumala IgG Ab [Titer] in Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40758897) Direct antiglobulin test.IgG specific reagent [Presence] on Red Blood Cells
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051651) Icteric interference index of Serum or Plasma
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(37020445) Astrovirus RNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
(37021247) Adenovirus 40+41 DNA [Presence] in Stool by NAA with probe detection
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3044927) Protein electrophoresis panel - Urine
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(40758895) Direct antiglobulin test.complement C3d specific reagent [Presence] on Red Blood Cells
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3051611) Lipemic interference index of Serum or Plasma
0
6
0.00
0.00
0.0
3.3
—
—
—
0
0
(4268621)
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3000492) Spirometry study
6
59
1.02
0.00
2.0
1.6
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
(40768441) Liver Pathology biopsy report
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(44806420)
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3014702) Chromogranin A [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.7
—
7.5
—
0
6
(3011648) Oxygen content in Venous blood
0
5
0.00
0.00
0.0
2.6
—
11.2
—
0
5
(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
5
51
0.98
0.00
13.0
7.8
%
0.5
0.7
—
5
51
(3017704) Immunofixation for Urine
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
(42869457) Rotavirus RNA [Identifier] in Stool by NAA with probe detection
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
(37020957) Sapovirus genogroups I+II+IV+V RNA [Presence] in Stool by NAA with probe detection
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
(3038177) Helicobacter pylori Ab [Presence] in Serum
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
(3012202) Varicella zoster virus DNA [Presence] in Specimen by NAA with probe detection
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
(3023410) Appearance of Cerebral spinal fluid
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_EYEPOSTOP and mortality.

Females

Parameter HR [95% CI] p-value
H7_EYEPOSTOP 1.239 [0.99, 1.54] 0.057
Birth year 0.994 [0.99, 1.0] 0.174

During the follow-up period (1.1.1998 — 31.12.2019), 153 out of 404 females with H7_EYEPOSTOP died.

Males

Parameter HR [95% CI] p-value
H7_EYEPOSTOP 1.275 [0.95, 1.71] 0.102
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 132 out of 311 males with H7_EYEPOSTOP died.

Mortality risk

Mortality risk for people of age

years, who have H7_EYEPOSTOP.

N-year risk Females Males
1 0.117% 0.248%
5 0.685% 1.393%
10 1.707% 3.671%
15 3.339% 6.617%
20 5.871% 11.493%

Relationships between endpoints

Index endpoint: H7_EYEPOSTOP – Postprocedural disorders of eye and adnexa, not elsewhere classified

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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