This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Keratopathy (bullous aphakic) following cataract surgery
H7_KERATOPATHY
eye disease: A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma. [NCIt:C26767]
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
29 |
4. Check minimum number of eventsNone |
29 |
5. Include endpointsNone |
29 |
6. Filter based on genotype QC (FinnGen only) |
27 |
Control definitions (FinnGen only)
- Control exclude
- H7_EYEPOSTOP
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H59
- Name in latin
- Syndroma corporis vitrei post operationem propter cataractam
Similar endpoints
↥List of similar endpoints to
Keratopathy (bullous aphakic) following cataract surgery
based on the number of shared cases.
Similar with more cases:
- Postprocedural disorders of eye and adnexa, not elsewhere classified
- Other disorders of eye and adnexa
- Diseases of the eye and adnexa
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 334 | 207 | 121 |
| Only index persons | 281 | 180 | 101 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | |||
| Whole population | 75.32 | 77.72 | 71.16 |
| Only index persons | 74.34 | 77.04 | 69.54 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 27 | 17 | 10 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.00 |
| Median age at first event (years) | 72.40 | 74.96 | 68.05 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
No data available
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
20
131
2.69
1.73
15.3
15.3
1.40
1.39
inr
—
7
46
20
137
2.47
1.50
6.4
6.1
10.55
10.41
umol/l
0.04
20
128
21
155
2.28
1.28
5.6
5.6
7.45
6.90
mmol/l
0.50
21
141
24
193
2.41
1.03
8.2
7.4
80.29
75.92
u/l
0.23
24
178
19
139
2.06
0.97
11.1
8.9
4.70
4.76
e9/l
0.04
19
122
6
29
2.34
0.96
1.2
3.9
5.33
12.67
umol/l
—
6
24
17
123
1.92
0.86
2.2
2.1
94.53
94.16
pmol/l
0.01
11
55
5
26
2.11
0.74
3.6
1.5
—
—
—
0
0
22
185
1.78
0.65
4.2
5.6
9.95
16.02
mm/h
2.46
22
167
6
36
1.84
0.61
1.2
1.7
—
—
—
0
0
0
23
0.00
0.61
0.0
1.4
—
—
—
0
0
6
38
1.73
0.58
1.2
1.7
—
—
—
0
0
6
39
1.68
0.57
6.8
8.4
109.17
103.44
mmol/l
—
6
39
14
106
1.62
0.53
2.4
2.6
—
—
—
0
0
14
106
1.62
0.53
3.9
3.3
—
—
—
0
0
5
31
1.74
0.46
4.0
4.0
8.48
7.81
ug/l
—
5
25
9
69
1.44
0.43
2.0
2.4
3.07
3.39
mg/l
—
9
61
5
78
0.57
0.43
1.0
3.2
391.00
364.13
umol/l
—
5
60
0
15
0.00
0.42
0.0
1.9
—
—
—
0
0
15
120
1.52
0.42
3.3
4.2
25.63
25.24
ng/l
—
10
98
16
134
1.43
0.33
3.6
4.2
0.00
0.00
estimate
—
5
30
0
11
0.00
0.22
0.0
2.4
—
131.03
—
0
6
0
14
0.00
0.20
0.0
1.8
—
—
—
0
0
15
136
1.21
0.12
4.5
5.5
0.00
0.00
estimate
—
5
28
15
137
1.20
0.10
3.9
4.2
0.00
0.00
estimate
—
5
27
9
100
0.86
0.08
4.0
4.5
—
—
—
0
0
10
97
1.05
0.00
2.2
2.5
96.30
104.34
ug/l
—
10
84
11
111
0.99
0.00
1.7
2.2
—
—
—
0
0
5
57
0.85
0.00
1.4
2.2
4.40
1.12
mg/l
—
5
51
7
67
1.06
-0.00
2.0
1.7
856.43
1184.97
nmol/l
—
7
49
6
58
1.04
-0.00
1.2
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.97
-0.00
1.9
2.5
45.38
53.42
u/l
—
8
72
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_KERATOPATHY and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_KERATOPATHY | 1.236 [0.93, 1.64] | 0.141 |
| Birth year | 0.999 [0.99, 1.01] | 0.78 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 182 females with H7_KERATOPATHY died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have H7_KERATOPATHY.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.138% | No data |
| 5 | 0.719% | No data |
| 10 | 2.05% | No data |
| 15 | 3.683% | No data |
| 20 | 6.548% | No data |
Relationships between endpoints
↥Index endpoint: H7_KERATOPATHY – Keratopathy (bullous aphakic) following cataract surgery
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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